{
    "uniprot_canonical_ac": "P0CI00-1",
    "uniprot_ac": "P0CI00",
    "uniprot_id": "Z705B_HUMAN",
    "mass": {
        "chemical_mass": 34732.0,
        "monoisotopic_mass": 34732.0
    },
    "refseq": {
        "ac": "NP_001180559",
        "name": "zinc finger protein 705B",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180559"
    },
    "gene_names": [
        {
            "name": "ZNF705B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P0CI00",
            "id": "P0CI00"
        },
        {
            "name": "ZNF705B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180559",
            "id": "NP_001180559"
        }
    ],
    "protein_names": [
        {
            "name": "Putative zinc finger protein 705B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P0CI00"
        },
        {
            "name": "Putative zinc finger protein 705D-like protein LOC100132396; putative zinc finger protein 705B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180559",
            "id": "NP_001180559"
        },
        {
            "name": "zinc finger protein 705B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180559",
            "id": "NP_001180559"
        }
    ],
    "function": [
        {
            "annotation": "May be involved in transcriptional regulation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0CI00",
                    "url": "https://www.uniprot.org/uniprot/P0CI00#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [
        {
            "tissue": {
                "name": "Adult mammalian kidney",
                "namespace": "UBERON",
                "id": "0000082",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000082"
            },
            "score": "18.51",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Stomach",
                "namespace": "UBERON",
                "id": "0000945",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000945"
            },
            "score": "16.41",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Esophagus",
                "namespace": "UBERON",
                "id": "0001043",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043"
            },
            "score": "17.43",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Rectum",
                "namespace": "UBERON",
                "id": "0001052",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001052"
            },
            "score": "16.94",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Urinary bladder",
                "namespace": "UBERON",
                "id": "0001255",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255"
            },
            "score": "16.34",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Thyroid gland",
                "namespace": "UBERON",
                "id": "0002046",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046"
            },
            "score": "14.44",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Liver",
                "namespace": "UBERON",
                "id": "0002107",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107"
            },
            "score": "16.88",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Prostate gland",
                "namespace": "UBERON",
                "id": "0002367",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367"
            },
            "score": "18.28",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        },
        {
            "tissue": {
                "name": "Thoracic mammary gland",
                "namespace": "UBERON",
                "id": "0005200",
                "url": "http://purl.obolibrary.org/obo/UBERON_0005200"
            },
            "score": "14.63",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000215356",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356"
                }
            ]
        }
    ],
    "expression_disease": [
        {
            "significant": "No",
            "trend": "up",
            "name": "Kidney cancer [DO disease name]",
            "url": "http://disease-ontology.org/term/DOID:263",
            "evidence": [
                {
                    "database": "BioXpress",
                    "id": "P0CI00",
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0CI00"
                }
            ],
            "disease": [
                {
                    "disease_id": "DOID:263",
                    "recommended_name": {
                        "id": "DOID:263",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:263",
                        "name": "kidney cancer",
                        "description": "A urinary system cancer that is located_in the kidney."
                    },
                    "synonyms": [
                        {
                            "id": "DOID:263",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:263",
                            "name": "malignant neoplasm of kidney except pelvis",
                            "description": ""
                        },
                        {
                            "id": "DOID:263",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:263",
                            "name": "malignant tumour of kidney",
                            "description": ""
                        },
                        {
                            "id": "DOID:263",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:263",
                            "name": "renal cancer",
                            "description": ""
                        }
                    ]
                }
            ]
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0CI00",
                    "url": "https://www.uniprot.org/uniprot/P0CI00"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "ZNF705B",
            "url": "https://www.uniprot.org/uniprot/P0CI00",
            "locus": {
                "chromosome": "8",
                "start_pos": 7952413,
                "end_pos": 7926337,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000215356",
                        "url": "https://www.ensembl.org/id/ENSG00000215356"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000215356",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000215356",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd07765",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ZNF705B",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=ZNF705B",
            "database": "GeneCards",
            "categories": [
                "Gene Annotation",
                "Organism-specific"
            ]
        },
        {
            "id": "100132396",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100132396",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "32284",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=32284",
            "database": "HGNC",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "IPR001909",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013087",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036051",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036236",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "hsa:100132396",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:100132396",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "NX_P0CI00",
            "url": "https://www.nextprot.org/entry/NX_P0CI00",
            "database": "neXtProt",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "HEIRGEC",
            "url": "https://omabrowser.org/oma/group/HEIRGEC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24381",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24381:SF30",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF30",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00096",
            "url": "http://pfam.xfam.org/family/PF00096",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01352",
            "url": "http://pfam.xfam.org/family/PF01352",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "P0CI00",
            "url": "https://pharos.nih.gov/targets/P0CI00",
            "database": "PHAROS",
            "categories": [
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            ]
        },
        {
            "id": "NP_001180559",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180559",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P0CI00",
            "url": "https://www.uniprot.org/uniprot/P0CI00",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P0CI00-1",
            "url": "https://www.uniprot.org/uniprot/P0CI00-1",
            "database": "UniProtKB",
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                "Protein"
            ]
        }
    ],
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        "sequence": "MHSLEKVTFEDVAIDFTQEEWDMMDTSKRKLYRDVMLENISHLVSLGYQISKSYIILQLEQGKELWWEGRVFLQDQNPDRESALKKKHMISMHPIIRKDTSTSMTMENSLILEDPFEYNDSGEDCTHSSTITQCLLTHSGKKPCVSKQCGKSLRNLLSPKPRKQIHTKGKSYQCNLCEKAYTNCFYLRRHKMTHTGERPYACHLCGKAFTQCSHLRRHEKTHTGERPYKCHQCGKAFIQSFNLRRHERTHLGQKCYECDKSGKAFSQSSGFRGNKIIHIGEKPPACLLCGKAFSLSSDLR",
        "length": 300,
        "header": "sp|P0CI00-1|Z705B_HUMAN Isoform 1 of Putative zinc finger protein 705B  OS=Homo sapiens OX=9606 GN=ZNF705B PE=5 SV=1 CANONICAL=P0CI00-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P0CI00-1",
            "url": "",
            "sequence": {
                "sequence": "MHSLEKVTFEDVAIDFTQEEWDMMDTSKRKLYRDVMLENISHLVSLGYQISKSYIILQLEQGKELWWEGRVFLQDQNPDRESALKKKHMISMHPIIRKDTSTSMTMENSLILEDPFEYNDSGEDCTHSSTITQCLLTHSGKKPCVSKQCGKSLRNLLSPKPRKQIHTKGKSYQCNLCEKAYTNCFYLRRHKMTHTGERPYACHLCGKAFTQCSHLRRHEKTHTGERPYKCHQCGKAFIQSFNLRRHERTHLGQKCYECDKSGKAFSQSSGFRGNKIIHIGEKPPACLLCGKAFSLSSDLR",
                "length": 300,
                "header": "sp|P0CI00-1|Z705B_HUMAN Isoform 1 of Putative zinc finger protein 705B  OS=Homo sapiens OX=9606 GN=ZNF705B PE=5 SV=1 CANONICAL=P0CI00-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 7952388,
                "end_pos": 7947422,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000400120.3",
                        "url": "https://www.ensembl.org/id/ENST00000400120.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000382987.3",
                        "url": "https://www.ensembl.org/id/ENSP00000382987.3"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "hsa:100132396",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:100132396",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "negative regulation of transcription by RNA polymerase II",
                        "id": "GO:0000122",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122",
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                                "url": "https://www.uniprot.org/uniprot/P0CI00"
                            }
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                        "pmid": ""
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            },
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                "name": "Cellular Component",
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                        "name": "nucleus",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
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                                "id": "P0CI00",
                                "url": "https://www.uniprot.org/uniprot/P0CI00"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
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                        "name": "metal ion binding",
                        "id": "GO:0046872",
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                                "id": "P0CI00",
                                "url": "https://www.uniprot.org/uniprot/P0CI00"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding",
                        "id": "GO:0000977",
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                        "evidence": [
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                                "id": "P0CI00",
                                "url": "https://www.uniprot.org/uniprot/P0CI00"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific",
                        "id": "GO:0001227",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227",
                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "P0CI00",
                                "url": "https://www.uniprot.org/uniprot/P0CI00"
                            }
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                        "pmid": ""
                    }
                ]
            }
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            "end_pos": 121,
            "annotation": "n_glycosylation_sequon"
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        {
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
    "sequence_features": {
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        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
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                "end_pos": 121
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                "end_pos": 41
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