{ "uniprot_canonical_ac": "P0CD60-1", "uniprot_ac": "P0CD60", "uniprot_id": "FRMC_DICDI", "mass": { "chemical_mass": 166978.0, "monoisotopic_mass": 166978.0 }, "refseq": {}, "gene_names": [ { "name": "frmC", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P0CD60", "id": "P0CD60" }, { "name": "DDB_G0289313", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/P0CD60", "id": "P0CD60" } ], "protein_names": [ { "name": "FERM domain-containing protein C", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P0CD60" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "P0CD60", "url": "https://www.uniprot.org/uniprot/P0CD60" } ], "common_name": "Cellular slime molds" } ], "gene": [ { "name": "frmC", "url": "https://www.uniprot.org/uniprot/P0CD60", "locus": {} } ], "crossref": [ { "id": "cd01765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "DDB_G0289313", "url": "http://dictybase.org/gene/DDB_G0289313", "database": "dictyBase", "categories": [ "Organism-specific" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HTINIQY", "url": "https://omabrowser.org/oma/group/HTINIQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19981:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19981:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "http://pfam.xfam.org/family/PF00373", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF09379", "url": "http://pfam.xfam.org/family/PF09379", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P0CD60", "url": "http://purl.obolibrary.org/obo/PR_P0CD60", "database": "PRO", "categories": [ "Protein" ] }, { "id": "P0CD60", "url": "https://www.uniprot.org/uniprot/P0CD60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0CD60-1", "url": "https://www.uniprot.org/uniprot/P0CD60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGVEDDLSKLLEELSSGVVLNNIQEKLNQSSPKLQSFIDDETGSNAEDVRRVLDAATDTESNYGGGANSITNTPNFNSHRGHQHLQLHTELSLDALRPVSENSPLHKSATRPISTSIRLPRLSVCEDDSSSSSSSSDGDSNSSSDSSDNSSEQSDDDDVHLHLHLHRHHRKVKEDEGDSFESSSESSEQYGSPSTLRRQEALKLEKIMQIQEKKKLLKEKLKEQDELELKEKQELNEITVQKEIKLKDKSNSVQNDIVDSDNNNNNNNNNSITIEEQQQEKQQQQQQHHHHHSTPNKPPKSRSVSISTPDSNIVVAGGNVISKERKRSILASFEEGSPMRSSSRLPSSRGGSIKIKVSKVLEEEMQLQQEFEKQEQLRHSARLSQLIRDLNMSSNLQDQQDQQLRKNENSNNNEGDDNNENVSNDNSSDNENQNINGSILIKEEQQEKIEITTTITTVITPPPPAQEPQHQQQPKILTPEEVEEERIRVLRIERMKDQVFSQLDELEDPLYSNGSRQRNGGGGGASTSAEPSMMQIPLTRLEDTASSSSSPTLQATKTTTTTTTTTTTTTTATLPINNKNLNIQGRPRKDSISDHWDIGRKEQPRRSMTLNIQRVGEDFSVKKAEAKKVNPDLEKILVHISLVDQSHKVICITEDFTVKDVIDLFSEKLGLVQTEFFSLAEVTSDGYDRWLDPNRAVKEAGIKNLSKLTFKIKYFKQPKKLSDSKAVHLYYLQIQQSVVNGTYPCSEAMSYRLSALQFYITFGAFDKDKHIAGFLDHGSLSEFIPSNFFFELTDEVIQKRLFHLHSQIKCSSSIEAKLRYLDLANKIPTFGVTSFQVFDGIRESSIVRQKRHLCVAEDGILISRKDRAGYDFFSYKEIISYQVTTRGLKIQIPHSSITPNTSETMSFDTSSYDQSNNIIDLMMGYKYFIQHDEFIRGIGAPVEQVDLNISLLLPLFQPPKIRTKSDPLRSRLELFKLNYLGLCQNFHTKPISKLIDQIDYILDKEGSFRNRLAFEKVELPSLNLRGSDLSFIADALKDTLNLIIEEGESIVENLNILSLDLSNNPLLATDAFEPLKIIMTCNTIIHLNLKNIGLSNKGVMPLVTIIEKYPNIETLQIGKNRVNESGVRVILRAIKNFNVKIETLGFEETNLTDSGCLIIDKLLSNNKTIKNLNISKNLITEEGFHHIFEGIKRNSLSLQDLNISGNKINSKLMIKFIKWLASSETSIITLNIAKTGLESSFGAELQKFLVGNSCHIKSLDTSYNDLGTSGTKNVIKGIINNQTITELSLCANKISSSGCNDLCQSLELASATCSKLYLRHCGLGSSSLVRIANMLELNKTITTLDLSMNEFSKSSSSAIGTMLEKNETLQEFYLADSSLGAREVESILNGLKNNSTIKKIFLDTNPIGKKGISSLANMLNTNTGLEVITLRHTNLNGKDILELLKQLSTNIPIKIINLTENTLDKITPQIKNAINDQIKRLHTINIQY", "length": 1489, "header": "sp|P0CD60-1|FRMC_DICDI Isoform 1 of FERM domain-containing protein C OS=Dictyostelium discoideum OX=44689 GN=frmC PE=4 SV=1 CANONICAL=P0CD60-1" }, "isoforms": [ { "isoform_ac": "P0CD60-1", "url": "", "sequence": { "sequence": "MEGVEDDLSKLLEELSSGVVLNNIQEKLNQSSPKLQSFIDDETGSNAEDVRRVLDAATDTESNYGGGANSITNTPNFNSHRGHQHLQLHTELSLDALRPVSENSPLHKSATRPISTSIRLPRLSVCEDDSSSSSSSSDGDSNSSSDSSDNSSEQSDDDDVHLHLHLHRHHRKVKEDEGDSFESSSESSEQYGSPSTLRRQEALKLEKIMQIQEKKKLLKEKLKEQDELELKEKQELNEITVQKEIKLKDKSNSVQNDIVDSDNNNNNNNNNSITIEEQQQEKQQQQQQHHHHHSTPNKPPKSRSVSISTPDSNIVVAGGNVISKERKRSILASFEEGSPMRSSSRLPSSRGGSIKIKVSKVLEEEMQLQQEFEKQEQLRHSARLSQLIRDLNMSSNLQDQQDQQLRKNENSNNNEGDDNNENVSNDNSSDNENQNINGSILIKEEQQEKIEITTTITTVITPPPPAQEPQHQQQPKILTPEEVEEERIRVLRIERMKDQVFSQLDELEDPLYSNGSRQRNGGGGGASTSAEPSMMQIPLTRLEDTASSSSSPTLQATKTTTTTTTTTTTTTTATLPINNKNLNIQGRPRKDSISDHWDIGRKEQPRRSMTLNIQRVGEDFSVKKAEAKKVNPDLEKILVHISLVDQSHKVICITEDFTVKDVIDLFSEKLGLVQTEFFSLAEVTSDGYDRWLDPNRAVKEAGIKNLSKLTFKIKYFKQPKKLSDSKAVHLYYLQIQQSVVNGTYPCSEAMSYRLSALQFYITFGAFDKDKHIAGFLDHGSLSEFIPSNFFFELTDEVIQKRLFHLHSQIKCSSSIEAKLRYLDLANKIPTFGVTSFQVFDGIRESSIVRQKRHLCVAEDGILISRKDRAGYDFFSYKEIISYQVTTRGLKIQIPHSSITPNTSETMSFDTSSYDQSNNIIDLMMGYKYFIQHDEFIRGIGAPVEQVDLNISLLLPLFQPPKIRTKSDPLRSRLELFKLNYLGLCQNFHTKPISKLIDQIDYILDKEGSFRNRLAFEKVELPSLNLRGSDLSFIADALKDTLNLIIEEGESIVENLNILSLDLSNNPLLATDAFEPLKIIMTCNTIIHLNLKNIGLSNKGVMPLVTIIEKYPNIETLQIGKNRVNESGVRVILRAIKNFNVKIETLGFEETNLTDSGCLIIDKLLSNNKTIKNLNISKNLITEEGFHHIFEGIKRNSLSLQDLNISGNKINSKLMIKFIKWLASSETSIITLNIAKTGLESSFGAELQKFLVGNSCHIKSLDTSYNDLGTSGTKNVIKGIINNQTITELSLCANKISSSGCNDLCQSLELASATCSKLYLRHCGLGSSSLVRIANMLELNKTITTLDLSMNEFSKSSSSAIGTMLEKNETLQEFYLADSSLGAREVESILNGLKNNSTIKKIFLDTNPIGKKGISSLANMLNTNTGLEVITLRHTNLNGKDILELLKQLSTNIPIKIINLTENTLDKITPQIKNAINDQIKRLHTINIQY", "length": 1489, "header": "sp|P0CD60-1|FRMC_DICDI Isoform 1 of FERM domain-containing protein C OS=Dictyostelium discoideum OX=44689 GN=frmC PE=4 SV=1 CANONICAL=P0CD60-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A", "evidence": [ { "database": "UniProtKB", "id": "P0CD60", "url": "https://www.uniprot.org/uniprot/P0CD60" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "P0CD60", "url": "https://www.uniprot.org/uniprot/P0CD60" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P0CD60", "url": "https://www.uniprot.org/uniprot/P0CD60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "P0CD60", "url": "https://www.uniprot.org/uniprot/P0CD60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1151, "end_pos": 1153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1167, "end_pos": 1169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1174, "end_pos": 1176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1203, "end_pos": 1205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1282, "end_pos": 1284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1339, "end_pos": 1341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1367, "end_pos": 1369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1394, "end_pos": 1396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1395, "end_pos": 1397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1124, "end_pos": 1126 }, { "start_pos": 1151, "end_pos": 1153 }, { "start_pos": 1167, "end_pos": 1169 }, { "start_pos": 1174, "end_pos": 1176 }, { "start_pos": 1203, "end_pos": 1205 }, { "start_pos": 1282, "end_pos": 1284 }, { "start_pos": 1339, "end_pos": 1341 }, { "start_pos": 1367, "end_pos": 1369 }, { "start_pos": 1394, "end_pos": 1396 }, { "start_pos": 1395, "end_pos": 1397 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 1458, "end_pos": 1460 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 741, "end_pos": 743 }, { "start_pos": 901, "end_pos": 903 }, { "start_pos": 949, "end_pos": 951 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }