{ "uniprot_canonical_ac": "P0C7U3-1", "uniprot_ac": "P0C7U3", "uniprot_id": "ZH11B_HUMAN", "mass": { "chemical_mass": 41895.0, "monoisotopic_mass": 41895.0 }, "refseq": {}, "gene_names": [ { "name": "ZDHHC11B", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P0C7U3", "id": "P0C7U3" } ], "protein_names": [ { "name": "Probable palmitoyltransferase ZDHHC11B", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P0C7U3" }, { "name": "2.3.1.225", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0C7U3" }, { "name": "DHHC-11B", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0C7U3" }, { "name": "Zinc finger DHHC domain-containing protein 11B", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0C7U3" } ], "function": [ { "annotation": "Probable palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (By similarity). May play a role in cell proliferation (PubMed:28331227).", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3#function" }, { "database": "PubMed", "id": "28331227", "url": "https://glygen.org/publication/PubMed/28331227" }, { "database": "UniProtKB", "id": "Q9H8X9", "url": "https://www.uniprot.org/uniprot/Q9H8X9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "80.98", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "64.95", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "86.16", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "79.23", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "82.85", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "82.85", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "77.82", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "75.69", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "76.43", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000206077", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000206077" } ] } ], "expression_disease": [ { "significant": "No", "trend": "up", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "P0C7U3", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0C7U3" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "No", "trend": "up", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "P0C7U3", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0C7U3" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - 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in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "P0C7U3", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0C7U3" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid neoplasm", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Kidney cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:263", "evidence": [ { "database": "BioXpress", "id": "P0C7U3", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0C7U3" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { "database": "BioXpress", "id": "P0C7U3", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0C7U3" } ], "disease": [ { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant hepato-biliary neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant tumor of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": 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"MDTRSGSQCSVTPEAIRNNEELVLPPRISRVNGWSLPLHYFRVVTWAVFVGLSLATFRIFIPLLPHSWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPRVLRTDPRYEDVKNMNTWLLFLPLFPVQVQTLIVVIIRMLVLLLDLLGLVQLGQLLIFHIYLKAKKMTTFEYLINTRKEESSKHQAVRKDPYVQMDKGFLQQGAGALGSSAQGVKAKSSLLIYKCPCHFCTSVNQDGDSKAQEADDAPSTSTLGLQQETTEPMKTDSAESED", "length": 371, "header": "sp|P0C7U3-1|ZH11B_HUMAN Isoform 1 of Probable palmitoyltransferase ZDHHC11B OS=Homo sapiens OX=9606 GN=ZDHHC11B PE=3 SV=1 CANONICAL=P0C7U3-1" }, "isoforms": [ { "isoform_ac": "A0A494BZX9-1", "url": "", "sequence": { "sequence": "MDTRSGSQCSVTPEAIRNNEELVLPPRISRVNGWSLPLHYFRVVTWAVFVGLSLATFRIFIPLLPHSWKYIAYVSLPQWGSGDTVSGTGGFLVSPTSRMKPQTLAEQENQTLHFLQ", "length": 116, "header": "tr|A0A494BZX9-1|ZH11B_HUMAN Computationally mapped isoform of Probable palmitoyltransferase ZDHHC11B OS=Homo sapiens OX=9606 GN=ZDHHC11B PE=3 SV=1 CANONICAL=P0C7U3-1" }, "locus": { "chromosome": "5", "start_pos": 766919, "end_pos": 755067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000651714.1", "url": "https://www.ensembl.org/id/ENST00000651714.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000498273.1", "url": "https://www.ensembl.org/id/ENSP00000498273.1" } ] } }, { "isoform_ac": "A0A494C0T6-1", "url": "", "sequence": { "sequence": "MDTRSGSQCSVTPEAIRNNEELVLPPRI", "length": 28, "header": "tr|A0A494C0T6-1|ZH11B_HUMAN Computationally mapped isoform of Probable palmitoyltransferase ZDHHC11B OS=Homo sapiens OX=9606 GN=ZDHHC11B PE=3 SV=1 CANONICAL=P0C7U3-1" }, "locus": { "chromosome": "5", "start_pos": 766919, "end_pos": 766836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000651083.1", "url": "https://www.ensembl.org/id/ENST00000651083.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000498706.1", "url": "https://www.ensembl.org/id/ENSP00000498706.1" } ] } }, { "isoform_ac": "A0A494C1T0-1", "url": "", "sequence": { "sequence": "MDTRSGSQCSVTPEAIRNNEELVLPPRISRVNGWSLPLHYFRV", "length": 43, "header": "tr|A0A494C1T0-1|ZH11B_HUMAN Computationally mapped isoform of Probable palmitoyltransferase ZDHHC11B OS=Homo sapiens OX=9606 GN=ZDHHC11B PE=3 SV=1 CANONICAL=P0C7U3-1" }, "locus": { "chromosome": "5", "start_pos": 766919, "end_pos": 766791, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000652055.1", "url": "https://www.ensembl.org/id/ENST00000652055.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000499203.1", "url": "https://www.ensembl.org/id/ENSP00000499203.1" } ] } }, { "isoform_ac": "A0A7P0TA36-1", "url": "", "sequence": { "sequence": "MDTRSGSQCSVTPEAIRNNEELVLPPRISRVNGWSLPLHYFRVVTWAVFVGLSLATFRIFIPLLPHSWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPRVLRTDPRYEAGRQSPACLRLQESAGEAAPTRHHLMYLLQQRQDPDQEDLGQRSPSGCRTRLPVSAPGMAAPALHTARVVRQGGLACPCSRTFRSQHGVTFFSRMSFASSTWKSLKLLLPLRSVTDASRASQPLLKHFLKASSTLARP", "length": 347, "header": "tr|A0A7P0TA36-1|ZH11B_HUMAN Computationally mapped isoform of Probable palmitoyltransferase ZDHHC11B OS=Homo sapiens OX=9606 GN=ZDHHC11B PE=3 SV=1 CANONICAL=P0C7U3-1" }, "locus": { "chromosome": "5", "start_pos": 766919, "end_pos": 749884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000522356.3", "url": "https://www.ensembl.org/id/ENST00000522356.3" }, { "database": "Ensembl Peptide", "id": "ENSP00000505988.1", "url": "https://www.ensembl.org/id/ENSP00000505988.1" } ] } }, { "isoform_ac": "P0C7U3-1", "url": "", "sequence": { "sequence": "MDTRSGSQCSVTPEAIRNNEELVLPPRISRVNGWSLPLHYFRVVTWAVFVGLSLATFRIFIPLLPHSWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPRVLRTDPRYEDVKNMNTWLLFLPLFPVQVQTLIVVIIRMLVLLLDLLGLVQLGQLLIFHIYLKAKKMTTFEYLINTRKEESSKHQAVRKDPYVQMDKGFLQQGAGALGSSAQGVKAKSSLLIYKCPCHFCTSVNQDGDSKAQEADDAPSTSTLGLQQETTEPMKTDSAESED", "length": 371, "header": "sp|P0C7U3-1|ZH11B_HUMAN Isoform 1 of Probable palmitoyltransferase ZDHHC11B OS=Homo sapiens OX=9606 GN=ZDHHC11B PE=3 SV=1 CANONICAL=P0C7U3-1" }, "locus": { "chromosome": "5", "start_pos": 766919, "end_pos": 716811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000508859.8", "url": "https://www.ensembl.org/id/ENST00000508859.8" }, { "database": "Ensembl Peptide", "id": "ENSP00000442373.2", "url": "https://www.ensembl.org/id/ENSP00000442373.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.", "journal": "Leukemia", "date": "2017", "authors": "Dzikiewicz-Krawczyk A, Kok K, Slezak-Prochazka I, Robertus JL, Bruining J, Tayari MM, Rutgers B, de Jong D, Koerts J, Seitz A, Li J, Tillema B, Guikema JE, Nolte IM, Diepstra A, Visser L, Kluiver J, van den Berg A", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "reference": [ { "type": "PubMed", "id": "28331227", "url": "https://glygen.org/publication/PubMed/28331227" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "pmid": "" }, { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "P0C7U3", "url": "https://www.uniprot.org/uniprot/P0C7U3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P09606-1", "Q2TGI8-1", "Q2TGJ1-1", "Q6DGF5-1", "Q2TGJ4-1", "Q2THW7-1", "Q76IC6-1", "Q2TGI5-1", "Q5FVR1-1", "E9PTT0-1", "Q32PY5-1", "Q2TGK3-1", "Q923G5-1", "Q9JKR5-1", "A0A8I6AR22-1", "Q2THW6-1", "A0A8I6G4A8-1", "Q2TGJ5-1", "A0A8I6ALH7-1", 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"A0A4D6K4L3-1", "A0A0B4LF16-1", "A1ZAR2-1", "Q9W251-1", "Q8IQN9-1", "Q7K3T4-1", "Q9VQK9-1", "Q9VBM5-1", "Q9VSV3-1", "Q9VBM4-1", "Q9VG80-1", "Q9I7L7-1", "Q9VBM8-1", "Q9VKN8-1", "Q9VB73-1", "Q0IGS7-1", "Q9VBM7-1", "Q9VPM2-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4LF16", "gene_name": "Dmel\\CG1407", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0A0B4LF16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4LF16" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A0B4LF16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4LF16" } ] } ] }, { "uniprot_ac": "A0A4D6K4L3", "gene_name": "Patsas", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0A4D6K4L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K4L3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A4D6K4L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K4L3" } ] } ] }, { "uniprot_ac": "A0A8I6ALH7", "gene_name": "Zdhhc11", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0A8I6ALH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ALH7" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8I6ALH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ALH7" } ] } ] }, { "uniprot_ac": "A0A8I6AR22", "gene_name": "Zdhhc20", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0A8I6AR22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AR22" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8I6AR22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AR22" } ] } ] }, { "uniprot_ac": "A0A8I6G292", "gene_name": "ENSRNOG00000067753", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0A8I6G292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G292" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8I6G292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G292" } ] } ] }, { "uniprot_ac": "A0A8I6G4A8", "gene_name": "Zdhhc16", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0A8I6G4A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G4A8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A8I6G4A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G4A8" } ] } ] }, { "uniprot_ac": "A0PK84", "gene_name": "Zdhhc22", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "A0PK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0PK84" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0PK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0PK84" } ] } ] }, { "uniprot_ac": "A1ZAR2", "gene_name": "Dmel\\CG17287", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", 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"https://www.uniprot.org/uniprot/A6J842" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A6J842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6J842" } ] } ] }, { "uniprot_ac": "E9PTT0", "gene_name": "Zdhhc17", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "E9PTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTT0" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "E9PTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTT0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E9PTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTT0" } ] } ] }, { "uniprot_ac": "E9PU37", "gene_name": "Zdhhc13", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "E9PU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PU37" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E9PU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PU37" } ] } ] }, { "uniprot_ac": "F7F2Z1", "gene_name": "Zdhhc1", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "F7F2Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7F2Z1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F7F2Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7F2Z1" } ] } ] }, { "uniprot_ac": "F7F533", "gene_name": "Zdhhc9", "activity": [ { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "F7F533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7F533" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F7F533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7F533" } ] } ] }, { "uniprot_ac": "P09606", "gene_name": "Glul", "activity": [ { "ec_number": "6.3.1.2", "activity": "ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate.", "evidence": [ { "id": "P09606", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09606" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P09606", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09606" } ] }, { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "P09606", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09606" } ] } ] }, { "uniprot_ac": "P0C7U3", "gene_name": "ZDHHC11B", "activity": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15104" } ] } ] }, { "uniprot_ac": "P15105", "gene_name": "Glul", "activity": [ { "ec_number": "6.3.1.2", "activity": "ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate.", "evidence": [ { "id": "P15105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15105" } ] }, { "ec_number": "2.3.1.225", "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].", "evidence": [ { "id": "P15105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15105" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P15105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15105" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "P15105", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15105" } ] } ] }, { "uniprot_ac": "P39010", "gene_name": "AKR1", "activity": [ { "ec_number": 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