{ "uniprot_canonical_ac": "P09466-1", "uniprot_ac": "P09466", "uniprot_id": "PAEP_HUMAN", "mass": { "chemical_mass": 20624.0, "monoisotopic_mass": 20624.0 }, "refseq": { "ac": "NP_001018058", "name": "glycodelin isoform 2 precursor", "summary": "This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" }, "gene_names": [ { "name": "PAEP", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P09466", "id": "P09466" }, { "name": "GD; GdA; GdF; GdS; PAEG; PEP; PP14; ZIF-1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058", "id": "NP_001018058" }, { "name": "PAEP", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058", "id": "NP_001018058" } ], "protein_names": [ { "name": "Glycodelin", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P09466" }, { "name": "GD", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "PAEG", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "PEG", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "PP14 protein (placental protein 14); alpha uterine protein; glycodelin-S; glycodelin-F; progesterone-associated endometrial protein; glycodelin-A; progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial a; PEG; pregnancy-associated endometrial alpha-2 globulin; zona-binding inhibitory factor-1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058", "id": "NP_001018058" }, { "name": "PP14", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "Placental protein 14", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "Pregnancy-associated endometrial alpha-2 globulin", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "Progestagen-associated endometrial protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "Progesterone-associated endometrial protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "ZIF-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "Zona-binding inhibitory factor-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P09466" }, { "name": "glycodelin isoform 2 precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058", "id": "NP_001018058" } ], "function": [ { "annotation": "Altered glycosylation of glycodelin in endometrial carcinoma.", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" }, { "database": "PubMed", "id": "32205858", "url": "https://glygen.org/publication/PubMed/32205858" } ] }, { "annotation": "Glycodelin is internalized by peripheral monocytes.", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" }, { "database": "PubMed", "id": "32120159", "url": "https://glygen.org/publication/PubMed/32120159" } ] }, { "annotation": "Glycodelin regulates the numbers and function of peripheral natural killer cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" }, { "database": "PubMed", "id": "31730930", "url": "https://glygen.org/publication/PubMed/31730930" } ] }, { "annotation": "Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466#function" }, { "database": "PubMed", "id": "12672671", "url": "https://glygen.org/publication/PubMed/12672671" }, { "database": "PubMed", "id": "9918684", "url": "https://glygen.org/publication/PubMed/9918684" }, { "database": "PubMed", "id": "17192260", "url": "https://glygen.org/publication/PubMed/17192260" }, { "database": "PubMed", "id": "7531163", "url": "https://glygen.org/publication/PubMed/7531163" }, { "database": "PubMed", "id": "15883155", "url": "https://glygen.org/publication/PubMed/15883155" } ] }, { "annotation": "Pregnancy Zone Protein (PZP) is significantly upregulated in the decidua of recurrent and spontaneous miscarriage and negatively correlated to Glycodelin A (GdA).", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" }, { "database": "PubMed", "id": "33388716", "url": "https://glygen.org/publication/PubMed/33388716" } ] }, { "annotation": "This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015].", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs1327054749", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1327054749" }, { "id": "rs1327054749", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1327054749#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 110, "end_pos": 110, "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NEA->NET).", "chr_id": "9", "chr_pos": "135564261", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A110", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1318521629", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1318521629" }, { "id": "rs1318521629", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1318521629" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "start_pos": 83, "end_pos": 83, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NNS->NNN).", "chr_id": "9", "chr_pos": "135562831", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S83", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs200987726", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200987726" }, { "id": "rs200987726", "database": "1000Genomes", "url": "https://www.ensembl.org/homo_sapiens/Variation/Explore?v=rs200987726" }, { "id": "rs200987726", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200987726" }, { "id": "rs200987726", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs200987726" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "start_pos": 83, "end_pos": 83, "sequence_org": "S", "sequence_mut": "R", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NNS->NNR).", "chr_id": "9", "chr_pos": "135562832", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "0.0002", "site_lbl": "S83", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "36.79", "present": "ABSENT", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "41.27", "present": "ABSENT", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "51.6", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "98.46", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "17.43", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "25.74", "present": "ABSENT", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "47.76", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "30.64", "present": "ABSENT", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "23.25", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "47.6", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "32.41", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "42.63", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "35.4", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000122133", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122133" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the 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"https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": 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"https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", 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"description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, intestinal", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Urinary bladder cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder 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"https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary 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"MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Head and neck cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. 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"https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "Nonsmall cell lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "alveolar cell carcinoma", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung neoplasm", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Breast cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1612", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "A thoracic cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "No", "trend": "up", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid neoplasm", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Kidney cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:263", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant hepato-biliary neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant tumor of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "non-resectable primary hepatic malignant neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "primary liver cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "primary malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "resectable malignant neoplasm of the liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, not specified as primary or secondary", "description": "" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Uterine cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:363", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:363", "recommended_name": { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine cancer", "description": "A female reproductive organ cancer that is located_in the uterus." }, "synonyms": [ { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "CA - cancer of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "Tumour of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterus neoplasm", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Esophageal cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:5041", "evidence": [ { "database": "BioXpress", "id": "P09466", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P09466" } ], "disease": [ { "disease_id": "DOID:5041", "recommended_name": { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is 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"https://proconsortium.org/app/entry/PR:000054612", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054613", "url": "https://proconsortium.org/app/entry/PR:000054613", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054614", "url": "https://proconsortium.org/app/entry/PR:000054614", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054615", "url": "https://proconsortium.org/app/entry/PR:000054615", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054616", "url": "https://proconsortium.org/app/entry/PR:000054616", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054617", "url": "https://proconsortium.org/app/entry/PR:000054617", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054618", "url": "https://proconsortium.org/app/entry/PR:000054618", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054619", "url": "https://proconsortium.org/app/entry/PR:000054619", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054620", "url": "https://proconsortium.org/app/entry/PR:000054620", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054621", "url": "https://proconsortium.org/app/entry/PR:000054621", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054622", "url": "https://proconsortium.org/app/entry/PR:000054622", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054623", "url": "https://proconsortium.org/app/entry/PR:000054623", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054624", "url": "https://proconsortium.org/app/entry/PR:000054624", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054625", "url": "https://proconsortium.org/app/entry/PR:000054625", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054626", "url": "https://proconsortium.org/app/entry/PR:000054626", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054627", "url": "https://proconsortium.org/app/entry/PR:000054627", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054628", "url": "https://proconsortium.org/app/entry/PR:000054628", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054629", "url": "https://proconsortium.org/app/entry/PR:000054629", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054630", "url": "https://proconsortium.org/app/entry/PR:000054630", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054631", "url": "https://proconsortium.org/app/entry/PR:000054631", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054632", "url": "https://proconsortium.org/app/entry/PR:000054632", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054633", "url": "https://proconsortium.org/app/entry/PR:000054633", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054634", "url": "https://proconsortium.org/app/entry/PR:000054634", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054635", "url": "https://proconsortium.org/app/entry/PR:000054635", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054636", "url": "https://proconsortium.org/app/entry/PR:000054636", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054637", "url": "https://proconsortium.org/app/entry/PR:000054637", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054638", "url": "https://proconsortium.org/app/entry/PR:000054638", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054639", "url": "https://proconsortium.org/app/entry/PR:000054639", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000054640", "url": "https://proconsortium.org/app/entry/PR:000054640", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR_P09466", "url": "http://purl.obolibrary.org/obo/PR_P09466", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P09466", "url": "DISABLED", "database": "UniCarbKB", "categories": [ "Glycoproteomics" ] }, { "id": "A6XNE0", "url": "https://www.uniprot.org/uniprot/A6XNE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A6XNE0-1", "url": "https://www.uniprot.org/uniprot/A6XNE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z349", "url": "https://www.uniprot.org/uniprot/F2Z349", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z349-1", "url": "https://www.uniprot.org/uniprot/F2Z349-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y4U4", "url": "https://www.uniprot.org/uniprot/H0Y4U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y4U4-1", "url": "https://www.uniprot.org/uniprot/H0Y4U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y530", "url": "https://www.uniprot.org/uniprot/H0Y530", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y530-1", "url": "https://www.uniprot.org/uniprot/H0Y530-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y6A4", "url": "https://www.uniprot.org/uniprot/H0Y6A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y6A4-1", "url": "https://www.uniprot.org/uniprot/H0Y6A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P09466-1", "url": "https://www.uniprot.org/uniprot/P09466-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P09466-2", "url": "https://www.uniprot.org/uniprot/P09466-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P09466-3", "url": "https://www.uniprot.org/uniprot/P09466-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5T6T6", "url": "https://www.uniprot.org/uniprot/Q5T6T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5T6T6-1", "url": "https://www.uniprot.org/uniprot/Q5T6T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 180, "header": "sp|P09466-1|PAEP_HUMAN Isoform 1 of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=2 CANONICAL=P09466-1" }, "isoforms": [ { "isoform_ac": "A6XNE0-1", "url": "", "sequence": { "sequence": "MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINSRVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 143, "header": "tr|A6XNE0-1|PAEP_HUMAN Computationally mapped isoform of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=1 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565798, "end_pos": 135561802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000611414.4", "url": "https://www.ensembl.org/id/ENST00000611414.4" }, { "database": "Ensembl Peptide", "id": "ENSP00000484659.1", "url": "https://www.ensembl.org/id/ENSP00000484659.1" } ] } }, { "isoform_ac": "F2Z349-1", "url": "", "sequence": { "sequence": "MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLESWWRTMRSCRDSSGLSGPCPGTYGTCWT", "length": 169, "header": "tr|F2Z349-1|PAEP_HUMAN Computationally mapped isoform of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=1 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565499, "end_pos": 135561802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000371768.7", "url": "https://www.ensembl.org/id/ENST00000371768.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000431712.1", "url": "https://www.ensembl.org/id/ENSP00000431712.1" } ] } }, { "isoform_ac": "H0Y4U4-1", "url": "", "sequence": { "sequence": "XVPAMDIPQTKQDLELPKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINCKASGAPQLSWKPQGPRTDPASSTARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 131, "header": "tr|H0Y4U4-1|PAEP_HUMAN Computationally mapped isoform of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=1 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565800, "end_pos": 135561846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000433563.5", "url": "https://www.ensembl.org/id/ENST00000433563.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000394216.1", "url": "https://www.ensembl.org/id/ENSP00000394216.1" } ] } }, { "isoform_ac": "H0Y530-1", "url": "", "sequence": { "sequence": "XEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 33, "header": "tr|H0Y530-1|PAEP_HUMAN Computationally mapped isoform of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=1 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565800, "end_pos": 135565432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000457014.1", "url": "https://www.ensembl.org/id/ENST00000457014.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000396196.1", "url": "https://www.ensembl.org/id/ENSP00000396196.1" } ] } }, { "isoform_ac": "H0Y6A4-1", "url": "", "sequence": { "sequence": "XPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 126, "header": "tr|H0Y6A4-1|PAEP_HUMAN Computationally mapped isoform of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=1 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565800, "end_pos": 135562362, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000454923.5", "url": "https://www.ensembl.org/id/ENST00000454923.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000404033.1", "url": "https://www.ensembl.org/id/ENSP00000404033.1" } ] } }, { "isoform_ac": "P09466-1", "url": "", "sequence": { "sequence": "MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 180, "header": "sp|P09466-1|PAEP_HUMAN Isoform 1 of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=2 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565798, "end_pos": 135561802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000277508.9", "url": "https://www.ensembl.org/id/ENST00000277508.9" }, { "database": "Ensembl Peptide", "id": "ENSP00000277508.5", "url": "https://www.ensembl.org/id/ENSP00000277508.5" } ] } }, { "isoform_ac": "P09466-2", "url": "", "sequence": { "sequence": "MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 158, "header": "sp|P09466-2|PAEP_HUMAN Isoform 2 of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=2 CANONICAL=P09466-1" }, "locus": {} }, { "isoform_ac": "P09466-3", "url": "", "sequence": { "sequence": "MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 86, "header": "sp|P09466-3|PAEP_HUMAN Isoform 3 of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=2 CANONICAL=P09466-1" }, "locus": {} }, { "isoform_ac": "Q5T6T6-1", "url": "", "sequence": { "sequence": "LMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF", "length": 132, "header": "tr|Q5T6T6-1|PAEP_HUMAN Computationally mapped isoform of Glycodelin OS=Homo sapiens OX=9606 GN=PAEP PE=1 SV=1 CANONICAL=P09466-1" }, "locus": { "chromosome": "9", "start_pos": 135565798, "end_pos": 135562342, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000418284.5", "url": "https://www.ensembl.org/id/ENST00000418284.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000401933.1", "url": "https://www.ensembl.org/id/ENSP00000401933.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G06356OH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G13290KJ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G14696LD", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G23294PN", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G24835MQ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G25837HW", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G27165KO", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G31916IQ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G33671BL", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G33876UV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G44339YF", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G46455GO", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G49874UX", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G51705EB", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G56749GV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G66116BW", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "ASN-46 ; ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G70418MS", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G72291OX", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G72667IM", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G75269BP", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "ASN-46 ; ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G76012OT", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G76675AB", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G80858MF", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G81877PA", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G82463GQ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G84452RH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G86705PH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G87889NL", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "ASN-46 ; ASN-46", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G92654OJ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G93856AJ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine Complex", "start_pos": 46, "start_aa": "Asn", "end_pos": 46, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn46", "evidence": [ { "id": "P09466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09466#ptm_processing" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G02628JF", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G08110WX", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G13290KJ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G14696LD", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G22310AV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G25837HW", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G27165KO", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G33671BL", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G33876UV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G44339YF", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G46455GO", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G51705EB", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G56749GV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G59821FL", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G60923RB", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "26791533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26791533" } ] }, { "glytoucan_ac": "G66116BW", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G70418MS", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G72667IM", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G75269BP", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G76012OT", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G76675AB", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G80858MF", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G81198YO", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G81877PA", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" }, { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ] }, { "glytoucan_ac": "G82592ZH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G85228QD", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G87051GH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "26791533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26791533" } ] }, { "glytoucan_ac": "G87889NL", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: N-46, N-81", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G93856AJ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G95977AE", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "177", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/177" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine Complex", "start_pos": 81, "start_aa": "Asn", "end_pos": 81, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn81", "evidence": [ { "id": "P09466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09466#ptm_processing" }, { "id": "7592613", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "glytoucan_ac": "G60923RB", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 82, "start_aa": "Asn", "end_pos": 82, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn82", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "26791533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26791533" } ] }, { "glytoucan_ac": "G87051GH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 82, "start_aa": "Asn", "end_pos": 82, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn82", "evidence": [ { "id": "P09466", "database": "UniCarbKB", "url": "" }, { "id": "26791533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26791533" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_reported" ], "publication": [ { "title": "Purification and characterization of an immunomodulatory endometrial protein, glycodelin.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Vigne J L, Hornung D, Mueller M D, Taylor R N", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "11278680", "url": "https://glygen.org/publication/PubMed/11278680" } ] }, { "title": "Zona-binding inhibitory factor-1 from human follicular fluid is an isoform of glycodelin.", "journal": "Biology of reproduction", "date": "2003", "authors": "Chiu PC, Koistinen R, Koistinen H, Seppala M, Lee KF, Yeung WS", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "12672671", "url": "https://glygen.org/publication/PubMed/12672671" } ] }, { "title": "Glycodelin-S in human seminal plasma reduces cholesterol efflux and inhibits capacitation of spermatozoa.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Chiu PC, Chung MK, Tsang HY, Koistinen R, Koistinen H, Seppala M, Lee KF, Yeung WS", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "15883155", "url": "https://glygen.org/publication/PubMed/15883155" } ] }, { "title": "Cumulus oophorus-associated glycodelin-C displaces sperm-bound glycodelin-A and -F and stimulates spermatozoa-zona pellucida binding.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Chiu PC, Chung MK, Koistinen R, Koistinen H, Seppala M, Ho PC, Ng EH, Lee KF, Yeung WS", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "17192260", "url": "https://glygen.org/publication/PubMed/17192260" } ] }, { "title": "Multiple forms of mRNA encoding human pregnancy-associated endometrial alpha 2-globulin, a beta-lactoglobulin homologue.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1991", "authors": "Garde J, Bell S C, Eperon I C", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "2006183", "url": "https://glygen.org/publication/PubMed/2006183" } ] }, { "title": "Human placental protein 14 gene: sequence and characterization of a short duplication.", "journal": "DNA Cell Biol.", "date": "1990", "authors": "Vaisse C, Atger M, Potier B, Milgrom E", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "2206398", "url": "https://glygen.org/publication/PubMed/2206398" } ] }, { "title": "The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans.", "journal": "Biochem. J.", "date": "2015", "authors": "Schiefner Andr\u00e9, Rodewald Fabian, Neumaier Irmgard, Skerra Arne", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "25422905", "url": "https://glygen.org/publication/PubMed/25422905" } ] }, { "title": "N-Glycoproteomics of Human Seminal Plasma Glycoproteins.", "journal": "Journal of proteome research", "date": "2016", "authors": "Saraswat M, Joenvaara S, Tomar AK, Singh S, Yadav S, Renkonen R", "evidence": [ { "database": "UniCarbKB", "id": "P09466", "url": "" } ], "reference": [ { "type": "PubMed", "id": "26791533", "url": "https://glygen.org/publication/PubMed/26791533" } ] }, { "title": "Glycodelin regulates the numbers and function of peripheral natural killer cells.", "journal": "Journal of reproductive immunology", "date": "2020", "authors": "Dixit A, Karande AA", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" } ], "reference": [ { "type": "PubMed", "id": "31730930", "url": "https://glygen.org/publication/PubMed/31730930" } ] }, { "title": "Complete amino acid sequence of human placental protein 14: a progesterone-regulated uterine protein homologous to beta-lactoglobulins.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1988", "authors": "Julkunen M, Sepp\u00e4l\u00e4 M, J\u00e4nne O A", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "3194393", "url": "https://glygen.org/publication/PubMed/3194393" } ] }, { "title": "Glycodelin is internalized by peripheral monocytes.", "journal": "Journal of reproductive immunology", "date": "2020", "authors": "Hansen YBL, Myrhoj V, Sorensen S", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" } ], "reference": [ { "type": "PubMed", "id": "32120159", "url": "https://glygen.org/publication/PubMed/32120159" } ] }, { "title": "Altered glycosylation of glycodelin in endometrial carcinoma.", "journal": "Laboratory investigation; a journal of technical methods and pathology", "date": "2020", "authors": "Hautala LC, Pang PC, Antonopoulos A, Pasanen A, Lee CL, Chiu PCN, Yeung WSB, Loukovaara M, Butzow R, Haslam SM, Dell A, Koistinen H", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" } ], "reference": [ { "type": "PubMed", "id": "32205858", "url": "https://glygen.org/publication/PubMed/32205858" } ] }, { "title": "Pregnancy Zone Protein (PZP) is significantly upregulated in the decidua of recurrent and spontaneous miscarriage and negatively correlated to Glycodelin A (GdA).", "journal": "Journal of reproductive immunology", "date": "2021", "authors": "Lob S, Vattai A, Kuhn C, Schmoeckel E, Mahner S, Wockel A, Kolben T, Keil C, Jeschke U, Vilsmaier T", "evidence": [ { "database": "RefSeq", "id": "NP_001018058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018058" } ], "reference": [ { "type": "PubMed", "id": "33388716", "url": "https://glygen.org/publication/PubMed/33388716" } ] }, { "title": "Amino acid sequence homology between human placental protein 14 and beta-lactoglobulins from various species.", "journal": "Endocrinology", "date": "1987", "authors": "Huhtala M L, Sepp\u00e4l\u00e4 M, N\u00e4rv\u00e4nen A, Palom\u00e4ki P, Julkunen M, Bohn H", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "3569148", "url": "https://glygen.org/publication/PubMed/3569148" } ] }, { "title": "Pregnancy-associated endometrial alpha 2-globulin, the major secretory protein of the luteal phase and first trimester pregnancy endometrium, is not glycosylated prolactin but related to beta-lactoglobulins.", "journal": "J. Clin. Endocrinol. Metab.", "date": "1987", "authors": "Bell SC, Keyte JW, Waites GT", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "3667877", "url": "https://glygen.org/publication/PubMed/3667877" } ] }, { "title": "Factors affecting fertilization: endometrial placental protein 14 reduces the capacity of human spermatozoa to bind to the human zona pellucida.", "journal": "Fertility and sterility", "date": "1995-02", "authors": "Oehninger S, Coddington C C, Hodgen G D, Seppala M", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "7531163", "url": "https://glygen.org/publication/PubMed/7531163" } ] }, { "title": "Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Dell A, Morris HR, Easton RL, Panico M, Patankar M, Oehniger S, Koistinen R, Koistinen H, Seppala M, Clark GF", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466#ptm_processing" }, { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" }, { "database": "UniCarbKB", "id": "P09466", "url": "" }, { "database": "GlyConnect", "id": "177", "url": "https://glyconnect.expasy.org/browser/proteins/177" } ], "reference": [ { "type": "PubMed", "id": "7592613", "url": "https://glygen.org/publication/PubMed/7592613" } ] }, { "title": "Gender-specific glycosylation of human glycodelin affects its contraceptive activity.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Morris HR, Dell A, Easton RL, Panico M, Koistinen H, Koistinen R, Oehninger S, Patankar MS, Seppala M, Clark GF", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "8943270", "url": "https://glygen.org/publication/PubMed/8943270" } ] }, { "title": "Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A.", "journal": "Mol. Hum. Reprod.", "date": "1996", "authors": "Koistinen H, Koistinen R, Dell A, Morris H R, Easton R L, Patankar M S, Oehninger S, Clark G F, Sepp\u00e4l\u00e4 M", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "9239694", "url": "https://glygen.org/publication/PubMed/9239694" } ] }, { "title": "Placental protein 14 functions as a direct T-cell inhibitor.", "journal": "Cellular immunology", "date": "1999-01-10", "authors": "Rachmilewitz J, Riely G J, Tykocinski M L", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "reference": [ { "type": "PubMed", "id": "9918684", "url": "https://glygen.org/publication/PubMed/9918684" } ] } ], "pathway": [ { "id": "hsa:5047", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:5047", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "pmid": "" }, { "name": "negative regulation of sperm capacitation", "id": "GO:1902491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902491", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "pmid": "" }, { "name": "regulation of binding of sperm to zona pellucida", "id": "GO:2000359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000359", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "pmid": "" }, { "name": "positive regulation of granulocyte macrophage colony-stimulating factor production", "id": "GO:0032725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032725", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "glycodelin N-glycosylated 1 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G13290KJ. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G13290KJ. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054604", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054604" } ] }, { "name": "glycodelin N-glycosylated 2 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G14696LD. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G14696LD. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054605", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054605" } ] }, { "name": "glycodelin N-glycosylated 3 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G25837HW. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G25837HW. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054606", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054606" } ] }, { "name": "glycodelin N-glycosylated 4 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G27165KO. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G27165KO. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054607", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054607" } ] }, { "name": "glycodelin N-glycosylated 5 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G33671BL. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G33671BL. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054608", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054608" } ] }, { "name": "glycodelin N-glycosylated 6 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G33876UV. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G33876UV. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054609", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054609" } ] }, { "name": "glycodelin N-glycosylated 7 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G44339YF. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G44339YF. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054610", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054610" } ] }, { "name": "glycodelin N-glycosylated 8 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G46455GO. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G46455GO. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054611", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054611" } ] }, { "name": "glycodelin N-glycosylated 9 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G56749GV. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G56749GV. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054612", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054612" } ] }, { "name": "glycodelin N-glycosylated 10 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G66116BW. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G66116BW. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054613", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054613" } ] }, { "name": "glycodelin N-glycosylated 11 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G75269BP. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G75269BP. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054614", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054614" } ] }, { "name": "glycodelin N-glycosylated 12 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G76012OT. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G76012OT. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054615", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054615" } ] }, { "name": "glycodelin N-glycosylated 13 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G76675AB. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G76675AB. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054616", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054616" } ] }, { "name": "glycodelin N-glycosylated 14 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G80858MF. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G80858MF. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054617", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054617" } ] }, { "name": "glycodelin N-glycosylated 15 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G81877PA. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G81877PA. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054618", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054618" } ] }, { "name": "glycodelin N-glycosylated 16 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G86705PH. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G86705PH. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054619", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054619" } ] }, { "name": "glycodelin N-glycosylated 17 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-46 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G87889NL. Example: UniProtKB:P09466-1, Asn-46, MOD:00160~GNO:G87889NL. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054620", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054620" } ] }, { "name": "glycodelin N-glycosylated 18 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G13290KJ. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G13290KJ. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054621", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054621" } ] }, { "name": "glycodelin N-glycosylated 19 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G14696LD. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G14696LD. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054622", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054622" } ] }, { "name": "glycodelin N-glycosylated 20 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G25837HW. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G25837HW. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054623", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054623" } ] }, { "name": "glycodelin N-glycosylated 21 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G27165KO. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G27165KO. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054624", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054624" } ] }, { "name": "glycodelin N-glycosylated 22 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G33671BL. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G33671BL. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054625", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054625" } ] }, { "name": "glycodelin N-glycosylated 23 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G33876UV. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G33876UV. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054626", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054626" } ] }, { "name": "glycodelin N-glycosylated 24 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G44339YF. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G44339YF. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054627", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054627" } ] }, { "name": "glycodelin N-glycosylated 25 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G46455GO. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G46455GO. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054628", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054628" } ] }, { "name": "glycodelin N-glycosylated 26 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G56749GV. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G56749GV. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054629", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054629" } ] }, { "name": "glycodelin N-glycosylated 27 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan composition is represented by GlyTouCan:G60923RB. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G60923RB. [PRO:DNx, PMID:26791533]", "evidence": [ { "id": "PR:000054630", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054630" } ] }, { "name": "glycodelin N-glycosylated 28 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G66116BW. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G66116BW. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054631", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054631" } ] }, { "name": "glycodelin N-glycosylated 29 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G75269BP. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G75269BP. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054632", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054632" } ] }, { "name": "glycodelin N-glycosylated 30 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G76012OT. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G76012OT. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054633", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054633" } ] }, { "name": "glycodelin N-glycosylated 31 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G76675AB. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G76675AB. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054634", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054634" } ] }, { "name": "glycodelin N-glycosylated 32 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G80858MF. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G80858MF. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054635", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054635" } ] }, { "name": "glycodelin N-glycosylated 33 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G81877PA. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G81877PA. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054636", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054636" } ] }, { "name": "glycodelin N-glycosylated 34 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan composition is represented by GlyTouCan:G87051GH. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G87051GH. [PRO:DNx, PMID:26791533]", "evidence": [ { "id": "PR:000054637", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054637" } ] }, { "name": "glycodelin N-glycosylated 35 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-81 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan structure is represented by GlyTouCan:G87889NL. Example: UniProtKB:P09466-1, Asn-81, MOD:00160~GNO:G87889NL. [PRO:DNx, PMID:7592613]", "evidence": [ { "id": "PR:000054638", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054638" } ] }, { "name": "glycodelin N-glycosylated 36 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-82 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan composition is represented by GlyTouCan:G60923RB. Example: UniProtKB:P09466-1, Asn-82, MOD:00160~GNO:G60923RB. [PRO:DNx, PMID:26791533]", "evidence": [ { "id": "PR:000054639", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054639" } ] }, { "name": "glycodelin N-glycosylated 37 (human)", "definition": "A glycodelin (human) that has been N-glycosylated at the residue equivalent to Asn-82 of the amino acid sequence represented by UniProtKB:P09466-1, in which the glycan composition is represented by GlyTouCan:G87051GH. Example: UniProtKB:P09466-1, Asn-82, MOD:00160~GNO:G87051GH. [PRO:DNx, PMID:26791533]", "evidence": [ { "id": "PR:000054640", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000054640" } ] } ], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Four distinct glycoforms A, C, F and S arise from different N-linked oligosaccharide chains at amino acid residues Asn-46 and Asn-81. Glycodelin-A and -F are taken up by the cumulus cells in which partial deglycosylation takes place to produce glycodelin-C.", "evidence": [ { "database": "UniProtKB", "id": "P09466", "url": "https://www.uniprot.org/uniprot/P09466" }, { "database": "PubMed", "id": "12672671", "url": "https://glygen.org/publication/PubMed/12672671" }, { "database": "PubMed", "id": "7592613", "url": "https://glygen.org/publication/PubMed/7592613" }, { "database": "PubMed", "id": "8943270", "url": "https://glygen.org/publication/PubMed/8943270" }, { "database": "PubMed", "id": "17192260", "url": "https://glygen.org/publication/PubMed/17192260" } ] } ], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [ 46, 81, 82 ], "o_linked_sites": [], "snv_sites": [ 83, 110 ], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 81, "end_pos": 83 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 65 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 41 }, { "field": "n_linked_glycan_sites", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 63 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 41 }, { "field": "n_linked_glycan_sites", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 20 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }