{ "uniprot_canonical_ac": "P08796-1", "uniprot_ac": "P08796", "uniprot_id": "CSA_DICDI", "mass": { "chemical_mass": 53655.0, "monoisotopic_mass": 53655.0 }, "refseq": { "ac": "XP_636399", "name": "cell adhesion molecule", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636399" }, "gene_names": [ { "name": "csaA", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P08796", "id": "P08796" }, { "name": "DDB_G0289073", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/P08796", "id": "P08796" }, { "name": "csaA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636399", "id": "XP_636399" } ], "protein_names": [ { "name": "Contact site A protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P08796" }, { "name": "CSA", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P08796" }, { "name": "Cell adhesion molecule gp80", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P08796" }, { "name": "Membrane-associated glycoprotein gp80", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P08796" }, { "name": "cell adhesion molecule", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636399", "id": "XP_636399" }, { "name": "contact site A protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636399", "id": "XP_636399" } ], "function": [ { "annotation": "This cell-surface glycoprotein mediates cell-cell binding via homophilic interaction.", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "common_name": "Cellular slime molds" } ], "gene": [ { "name": "csaA", "url": "https://www.uniprot.org/uniprot/P08796", "locus": {} } ], "crossref": [ { "id": "DDB_G0289073", "url": "http://dictybase.org/gene/DDB_G0289073", "database": "dictyBase", "categories": [ "Organism-specific" ] }, { "id": "8626958", "url": "https://www.ncbi.nlm.nih.gov/gene/8626958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ddi:DDB_G0289073", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0289073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNNGRIG", "url": "https://omabrowser.org/oma/group/PNNGRIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31341:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31341:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR_P08796", "url": "http://purl.obolibrary.org/obo/PR_P08796", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_636399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P08796-1", "url": "https://www.uniprot.org/uniprot/P08796-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFLLVLIILYNILNSAHSAPTITAVSNGKFGVPTYITITGTGFTGTPVVTIGGQTCDPVIVANTASLQCQFSAQLAPGNSNFDVIVKVGGVPSTGGNGLFKYTPPTLSTIFPNNGRIGMILVDGPSNISGYKLNVNDSINSAMLSVTADSVSPTIYFLVPNTIAGGLLNLELIQPFGFSTIVTSKSVFSPTITSITPLAFDLTPTNVTVTGKYFGTTASVTMGSHIYTGLTVQDDGTNCHVIFTTRSVYESSNTITAKASTGVDMIYLDNQGNQQPITFTYNPPTITSTKQVNDSVEISTTNTGTDFTQISLTMGTSSPTNLVITGTNEKIVITLPHALPEGEIQFNLKAGISNVVTSTLLVTPVINSVTQAPHNGGSITISGIFLNNAHVSIVVDQNTTDIVCAPDSNGESIICPVEAGSGTINLVVTNYKNFASDPTIKTEATTSTTYTIPDTPTPTDTATPSPTPTETATPSPTPKPTSTPEETEAPSSATTLISPLSLIVIFISFVLLI", "length": 514, "header": "sp|P08796-1|CSA_DICDI Isoform 1 of Contact site A protein OS=Dictyostelium discoideum OX=44689 GN=csaA PE=1 SV=3 CANONICAL=P08796-1" }, "isoforms": [ { "isoform_ac": "P08796-1", "url": "", "sequence": { "sequence": "MKFLLVLIILYNILNSAHSAPTITAVSNGKFGVPTYITITGTGFTGTPVVTIGGQTCDPVIVANTASLQCQFSAQLAPGNSNFDVIVKVGGVPSTGGNGLFKYTPPTLSTIFPNNGRIGMILVDGPSNISGYKLNVNDSINSAMLSVTADSVSPTIYFLVPNTIAGGLLNLELIQPFGFSTIVTSKSVFSPTITSITPLAFDLTPTNVTVTGKYFGTTASVTMGSHIYTGLTVQDDGTNCHVIFTTRSVYESSNTITAKASTGVDMIYLDNQGNQQPITFTYNPPTITSTKQVNDSVEISTTNTGTDFTQISLTMGTSSPTNLVITGTNEKIVITLPHALPEGEIQFNLKAGISNVVTSTLLVTPVINSVTQAPHNGGSITISGIFLNNAHVSIVVDQNTTDIVCAPDSNGESIICPVEAGSGTINLVVTNYKNFASDPTIKTEATTSTTYTIPDTPTPTDTATPSPTPTETATPSPTPKPTSTPEETEAPSSATTLISPLSLIVIFISFVLLI", "length": 514, "header": "sp|P08796-1|CSA_DICDI Isoform 1 of Contact site A protein OS=Dictyostelium discoideum OX=44689 GN=csaA PE=1 SV=3 CANONICAL=P08796-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 128, "start_aa": "Asn", "end_pos": 128, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn128", "evidence": [ { "id": "P08796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08796#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 137, "start_aa": "Asn", "end_pos": 137, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn137", "evidence": [ { "id": "P08796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08796#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 207, "start_aa": "Asn", "end_pos": 207, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn207", "evidence": [ { "id": "P08796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08796#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 294, "start_aa": "Asn", "end_pos": 294, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn294", "evidence": [ { "id": "P08796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08796#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 399, "start_aa": "Asn", "end_pos": 399, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn399", "evidence": [ { "id": "P08796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08796#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Identification of a unique cAMP-response element in the gene encoding the cell adhesion molecule gp80 in Dictyostelium discoideum.", "journal": "J. Biol. Chem.", "date": "1992", "authors": "Desbarats L, Lam T Y, Wong L M, Siu C H", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "1326559", "url": "https://glygen.org/publication/PubMed/1326559" } ] }, { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] }, { "title": "Complete sequence and transcript regulation of a cell adhesion protein from aggregating Dictyostelium cells.", "journal": "EMBO J.", "date": "1986", "authors": "Noegel A, Gerisch G, Stadler J, Westphal M", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "16453689", "url": "https://glygen.org/publication/PubMed/16453689" } ] }, { "title": "Cloning of cDNA for the contact site A glycoprotein of Dictyostelium discoideum.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1986", "authors": "Wong L M, Siu C H", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "16593709", "url": "https://glygen.org/publication/PubMed/16593709" } ] }, { "title": "Identification of an octapeptide involved in homophilic interaction of the cell adhesion molecule gp80 of Dictyostelium discoideum.", "journal": "Cell", "date": "1989", "authors": "Kamboj R K, Gariepy J, Siu C H", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "2582489", "url": "https://glygen.org/publication/PubMed/2582489" } ] }, { "title": "The contact site A glycoprotein of Dictyostelium discoideum carries a phospholipid anchor of a novel type.", "journal": "EMBO J.", "date": "1989", "authors": "Stadler J, Keenan T W, Bauer G, Gerisch G", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "2721485", "url": "https://glygen.org/publication/PubMed/2721485" } ] }, { "title": "Molecular mechanisms of cell-cell interaction in Dictyostelium discoideum.", "journal": "Biochem. Cell Biol.", "date": "1988", "authors": "Siu C H, Wong L M, Lam T Y, Kamboj R K, Choi A, Cho A", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "3063296", "url": "https://glygen.org/publication/PubMed/3063296" } ] }, { "title": "Mapping of a cell-binding domain in the cell adhesion molecule gp80 of Dictyostelium discoideum.", "journal": "J. Cell Biol.", "date": "1988", "authors": "Kamboj R K, Wong L M, Lam T Y, Siu C H", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "3182938", "url": "https://glygen.org/publication/PubMed/3182938" } ] }, { "title": "Improved purification and N-terminal amino acid sequence determination of the contact site A glycoprotein of Dictyostelium discoideum.", "journal": "Hoppe-Seyler's Z. Physiol. Chem.", "date": "1982", "authors": "Stadler J, Bordier C, Lottspeich F, Henschen A, Gerisch G", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "reference": [ { "type": "PubMed", "id": "7118072", "url": "https://glygen.org/publication/PubMed/7118072" } ] } ], "pathway": [ { "id": "ddi:DDB_G0289073", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0289073", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "response to curcumin", "id": "GO:1904643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904643", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "cell-cell adhesion via plasma-membrane adhesion molecules", "id": "GO:0098742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098742", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "response to UV-C", "id": "GO:0010225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010225", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules", "id": "GO:0016338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016338", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "sorocarp development", "id": "GO:0030587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030587", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "aggregation involved in sorocarp development", "id": "GO:0031152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031152", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" }, { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "P08796", "url": "https://www.uniprot.org/uniprot/P08796" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [ 128, 137, 207, 294, 399 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 399, "end_pos": 401 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 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