{
    "uniprot_canonical_ac": "P04988-1",
    "uniprot_ac": "P04988",
    "uniprot_id": "CYSP1_DICDI",
    "mass": {
        "chemical_mass": 38510.0,
        "monoisotopic_mass": 38510.0
    },
    "refseq": {
        "ac": "XP_635417",
        "name": "cysteine proteinase 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635417"
    },
    "gene_names": [
        {
            "name": "cprA",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P04988",
            "id": "P04988"
        },
        {
            "name": "CP1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P04988",
            "id": "P04988"
        },
        {
            "name": "DDB_G0290957",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P04988",
            "id": "P04988"
        },
        {
            "name": "cprA",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635417",
            "id": "XP_635417"
        }
    ],
    "protein_names": [
        {
            "name": "Cysteine proteinase 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P04988"
        },
        {
            "name": "3.4.22.-",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P04988"
        },
        {
            "name": "cysteine proteinase 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635417",
            "id": "XP_635417"
        }
    ],
    "function": [
        {
            "annotation": "Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P04988",
                    "url": "https://www.uniprot.org/uniprot/P04988#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Dictyostelium discoideum",
            "taxid": 44689,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P04988",
                    "url": "https://www.uniprot.org/uniprot/P04988"
                }
            ],
            "common_name": "Cellular slime molds"
        }
    ],
    "gene": [
        {
            "name": "cprA",
            "url": "https://www.uniprot.org/uniprot/P04988",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "cd02248",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02248",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "DDB_G0290957",
            "url": "http://dictybase.org/gene/DDB_G0290957",
            "database": "dictyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "8627918",
            "url": "https://www.ncbi.nlm.nih.gov/gene/8627918",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "118",
            "url": "https://glyconnect.expasy.org/browser/proteins/118",
            "database": "GlyConnect",
            "categories": [
                "Glycoproteomics",
                "Glycan"
            ]
        },
        {
            "id": "IPR000169",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000668",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000668",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013128",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013128",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013201",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013201",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR025660",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR025660",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR025661",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR025661",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038765",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039417",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039417",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ddi:DDB_G0290957",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0290957",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "CDPEERN",
            "url": "https://omabrowser.org/oma/group/CDPEERN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12411",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12411",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12411:SF947",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12411:SF947",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00112",
            "url": "http://pfam.xfam.org/family/PF00112",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF08246",
            "url": "http://pfam.xfam.org/family/PF08246",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P04988",
            "url": "http://purl.obolibrary.org/obo/PR_P04988",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-DDI-114608",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-114608",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-2132295",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-2132295",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_635417",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635417",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P04988",
            "url": "https://www.uniprot.org/uniprot/P04988",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P04988-1",
            "url": "https://www.uniprot.org/uniprot/P04988-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MKVILLFVLAVFTVFVSSRGIPLEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEQACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII",
        "length": 343,
        "header": "sp|P04988-1|CYSP1_DICDI Isoform 1 of Cysteine proteinase 1  OS=Dictyostelium discoideum OX=44689 GN=cprA PE=2 SV=2 CANONICAL=P04988-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P04988-1",
            "url": "",
            "sequence": {
                "sequence": "MKVILLFVLAVFTVFVSSRGIPLEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEQACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII",
                "length": 343,
                "header": "sp|P04988-1|CYSP1_DICDI Isoform 1 of Cysteine proteinase 1  OS=Dictyostelium discoideum OX=44689 GN=cprA PE=2 SV=2 CANONICAL=P04988-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "G68544GH",
            "type": "O-linked",
            "subtype": "",
            "site_category": "reported_with_glycan",
            "site_seq": "",
            "relation": "attached",
            "comment": "",
            "evidence": [
                {
                    "id": "118",
                    "database": "GlyConnect",
                    "url": "https://glyconnect.expasy.org/browser/proteins/118"
                },
                {
                    "id": "6993483",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/6993483"
                },
                {
                    "id": "6438439",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/6438439"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme",
        "glycoprotein",
        "glycoprotein_reported_with_glycan"
    ],
    "publication": [
        {
            "title": "The genome of the social amoeba Dictyostelium discoideum.",
            "journal": "Nature",
            "date": "2005",
            "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P04988",
                    "url": "https://www.uniprot.org/uniprot/P04988"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15875012",
                    "url": "https://glygen.org/publication/PubMed/15875012"
                }
            ]
        },
        {
            "title": "A developmentally regulated cysteine proteinase in Dictyostelium discoideum.",
            "journal": "EMBO J.",
            "date": "1985",
            "authors": "Williams J G, North M J, Mahbubani H",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P04988",
                    "url": "https://www.uniprot.org/uniprot/P04988"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "2990918",
                    "url": "https://glygen.org/publication/PubMed/2990918"
                }
            ]
        },
        {
            "title": "O beta-(N-acetyl-alpha-glucosamine-1-phosphoryl)serine in proteinase I from Dictyostelium discoideum.",
            "journal": "Methods in enzymology",
            "date": "1984",
            "authors": "Gustafson G L, Gander J E",
            "evidence": [
                {
                    "database": "GlyConnect",
                    "id": "118",
                    "url": "https://glyconnect.expasy.org/browser/proteins/118"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "6438439",
                    "url": "https://glygen.org/publication/PubMed/6438439"
                }
            ]
        },
        {
            "title": "Occurrence of N-acetylglucosamine-1-phosphate in proteinase I from Dictyostelium discoideum.",
            "journal": "The Journal of biological chemistry",
            "date": "1980-08-10",
            "authors": "Gustafson G L, Milner L A",
            "evidence": [
                {
                    "database": "GlyConnect",
                    "id": "118",
                    "url": "https://glyconnect.expasy.org/browser/proteins/118"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "6993483",
                    "url": "https://glygen.org/publication/PubMed/6993483"
                }
            ]
        },
        {
            "title": "A lysosomal cysteine proteinase from Dictyostelium discoideum contains N-acetylglucosamine-1-phosphate bound to serine but not mannose-6-phosphate on N-linked oligosaccharides.",
            "journal": "J. Biol. Chem.",
            "date": "1996",
            "authors": "Mehta D P, Ichikawa M, Salimath P V, Etchison J R, Haak R, Manzi A, Freeze H H",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P04988",
                    "url": "https://www.uniprot.org/uniprot/P04988"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "8631906",
                    "url": "https://glygen.org/publication/PubMed/8631906"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "ddi:DDB_G0290957",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0290957",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DDI-114608",
            "name": "Platelet degranulation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-114608",
            "resource": "Reactome",
            "description": "Platelet degranulation"
        },
        {
            "id": "R-DDI-2132295",
            "name": "MHC class II antigen presentation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-2132295",
            "resource": "Reactome",
            "description": "MHC class II antigen presentation"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "extracellular space",
                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P04988",
                                "url": "https://www.uniprot.org/uniprot/P04988"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lysosome",
                        "id": "GO:0005764",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P04988",
                                "url": "https://www.uniprot.org/uniprot/P04988"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "cysteine-type endopeptidase activity",
                        "id": "GO:0004197",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P04988",
                                "url": "https://www.uniprot.org/uniprot/P04988"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "proteolysis involved in protein catabolic process",
                        "id": "GO:0051603",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P04988",
                                "url": "https://www.uniprot.org/uniprot/P04988"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hyperosmotic response",
                        "id": "GO:0006972",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006972",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P04988",
                                "url": "https://www.uniprot.org/uniprot/P04988"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 237,
            "end_pos": 239,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 244,
            "end_pos": 246,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "R-DDI-2130706",
            "name": "MHC class II antigen processing",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "lysosomal lumen",
            "input_participant_list": [
                "R-ALL-2213225"
            ],
            "output_participant_list": [
                "R-ALL-2213226"
            ],
            "enzyme_list": [
                "Q54QD9-1",
                "Q94503-1",
                "O76856-1",
                "P04988-1",
                "P04989-1",
                "P54639-1",
                "P54640-1",
                "Q23894-1",
                "Q54ME1-1",
                "Q94504-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-2130706",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-2130706"
                }
            ]
        },
        {
            "id": "R-DDI-481009",
            "name": "Exocytosis of platelet dense granule content",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P04988-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-481009",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-481009"
                }
            ]
        }
    ],
    "reaction_participants": [
        {
            "participant_id": "R-ALL-2213225",
            "participant_name": "unfolded antigen [lysosomal lumen]",
            "crossref": [
                {
                    "id": "23367",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "23367",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "23367",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "23367",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "23367",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "23367",
                    "database": "ChEBI",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-ALL-2213226",
            "participant_name": "MHC class II epitopes [lysosomal lumen]",
            "crossref": [
                {
                    "id": "15841",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "15841",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "15841",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "15841",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "15841",
                    "database": "ChEBI",
                    "url": ""
                },
                {
                    "id": "15841",
                    "database": "ChEBI",
                    "url": ""
                }
            ]
        }
    ],
    "reaction_enzymes": [
        {
            "uniprot_ac": "O76856",
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                {
                    "ec_number": "3.4.23.5",
                    "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.",
                    "evidence": [
                        {
                            "id": "O76856",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O76856"
                        }
                    ]
                },
                {
                    "ec_number": "3.4.23.5",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O76856",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O76856"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P04988",
            "gene_name": "cprA",
            "activity": [
                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P04988",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04988"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P04989",
            "gene_name": "cprB",
            "activity": [
                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P04989",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P04989"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54639",
            "gene_name": "cprD",
            "activity": [
                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54639",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54639"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54640",
            "gene_name": "cprE",
            "activity": [
                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
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                            "id": "P54640",
                            "database": "UniProtKB",
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q23894",
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                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q23894",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23894"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54ME1",
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                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
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                            "id": "Q54ME1",
                            "database": "UniProtKB",
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                    ]
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            ]
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        {
            "uniprot_ac": "Q54QD9",
            "gene_name": "ctsB",
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                {
                    "ec_number": "3.4.22.1",
                    "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.",
                    "evidence": [
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                    ]
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                {
                    "ec_number": "3.4.22.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54QD9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54QD9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q94503",
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            "activity": [
                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q94503",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q94503"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q94504",
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                {
                    "ec_number": "3.4.22.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q94504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q94504"
                        }
                    ]
                }
            ]
        }
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    "biomarkers": [],
    "synthesized_glycans": [],
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    "sequence_features": {
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        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
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                "end_pos": 239
            },
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                "start_pos": 244,
                "end_pos": 246
            }
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}
