{
    "uniprot_canonical_ac": "O96390-1",
    "uniprot_ac": "O96390",
    "uniprot_id": "RACF1_DICDI",
    "mass": {
        "chemical_mass": 21830.0,
        "monoisotopic_mass": 21830.0
    },
    "refseq": {
        "ac": "XP_646071",
        "name": "Rho GTPase",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646071"
    },
    "gene_names": [
        {
            "name": "racF1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/O96390",
            "id": "O96390"
        },
        {
            "name": "DDB_G0269176",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O96390",
            "id": "O96390"
        },
        {
            "name": "racF1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646071",
            "id": "XP_646071"
        }
    ],
    "protein_names": [
        {
            "name": "Rho-related protein racF1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "O96390"
        },
        {
            "name": "Rho GTPase",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646071",
            "id": "XP_646071"
        }
    ],
    "function": [
        {
            "annotation": "Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96390",
                    "url": "https://www.uniprot.org/uniprot/O96390#function"
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    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Dictyostelium discoideum",
            "taxid": 44689,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96390",
                    "url": "https://www.uniprot.org/uniprot/O96390"
                }
            ],
            "common_name": "Cellular slime molds"
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    ],
    "gene": [
        {
            "name": "racF1",
            "url": "https://www.uniprot.org/uniprot/O96390",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "cd00157",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00157",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "DDB_G0269176",
            "url": "http://dictybase.org/gene/DDB_G0269176",
            "database": "dictyBase",
            "categories": [
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        },
        {
            "id": "8617020",
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            "categories": [
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        },
        {
            "id": "O96390",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:O96390*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001806",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003578",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005225",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027417",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ddi:DDB_G0269176",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0269176",
            "database": "KEGG Pathway",
            "categories": [
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        },
        {
            "id": "EKPICME",
            "url": "https://omabrowser.org/oma/group/EKPICME/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24072",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24072:SF359",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072:SF359",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00071",
            "url": "http://pfam.xfam.org/family/PF00071",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_O96390",
            "url": "http://purl.obolibrary.org/obo/PR_O96390",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-DDI-6798695",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-6798695",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-9013404",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013404",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-9013407",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013407",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-9013408",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013408",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-9013418",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013418",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-9013422",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013422",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_646071",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646071",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "O96390",
            "url": "https://www.uniprot.org/uniprot/O96390",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "O96390-1",
            "url": "https://www.uniprot.org/uniprot/O96390-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MQNIKCVVVGDGAVGKTCMLISYTTNGFPSEYIPTVFDNYCANLMLEGKPYSLGLWDTAGQEDYDRLRPLSYPHTDVFLICFSIISQASFENVTTKWFKEVNHHAPGVPIILVGTKQDIRNDNDSIKKLKEKNIELVPYEKGLEKAKEINAIYLEASALTQRGIKDVFDQCIRSVIYPNKLIKKPKKKSCTIM",
        "length": 193,
        "header": "sp|O96390-1|RACF1_DICDI Isoform 1 of Rho-related protein racF1  OS=Dictyostelium discoideum OX=44689 GN=racF1 PE=1 SV=1 CANONICAL=O96390-1"
    },
    "isoforms": [
        {
            "isoform_ac": "O96390-1",
            "url": "",
            "sequence": {
                "sequence": "MQNIKCVVVGDGAVGKTCMLISYTTNGFPSEYIPTVFDNYCANLMLEGKPYSLGLWDTAGQEDYDRLRPLSYPHTDVFLICFSIISQASFENVTTKWFKEVNHHAPGVPIILVGTKQDIRNDNDSIKKLKEKNIELVPYEKGLEKAKEINAIYLEASALTQRGIKDVFDQCIRSVIYPNKLIKKPKKKSCTIM",
                "length": 193,
                "header": "sp|O96390-1|RACF1_DICDI Isoform 1 of Rho-related protein racF1  OS=Dictyostelium discoideum OX=44689 GN=racF1 PE=1 SV=1 CANONICAL=O96390-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "RacF1, a novel member of the Rho protein family in Dictyostelium discoideum, associates transiently with cell contact areas, macropinosomes and phagosomes.",
            "journal": "Mol. Biol. Cell",
            "date": "1999",
            "authors": "Rivero F, Albrecht R, Dislich H, Bracco E, Graciotti L, Bozzaro S, Noegel A A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96390",
                    "url": "https://www.uniprot.org/uniprot/O96390"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10198067",
                    "url": "https://glygen.org/publication/PubMed/10198067"
                }
            ]
        },
        {
            "title": "Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB.",
            "journal": "Mol. Biol. Cell",
            "date": "2005",
            "authors": "de la Roche Marc, Mahasneh Amjad, Lee Sheu-Fen, Rivero Francisco, C\u00f4t\u00e9 Graham P",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96390",
                    "url": "https://www.uniprot.org/uniprot/O96390"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15509655",
                    "url": "https://glygen.org/publication/PubMed/15509655"
                }
            ]
        },
        {
            "title": "The genome of the social amoeba Dictyostelium discoideum.",
            "journal": "Nature",
            "date": "2005",
            "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96390",
                    "url": "https://www.uniprot.org/uniprot/O96390"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15875012",
                    "url": "https://glygen.org/publication/PubMed/15875012"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "ddi:DDB_G0269176",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0269176",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DDI-6798695",
            "name": "Neutrophil degranulation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-6798695",
            "resource": "Reactome",
            "description": "Neutrophil degranulation"
        },
        {
            "id": "R-DDI-9013404",
            "name": "RAC2 GTPase cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013404",
            "resource": "Reactome",
            "description": "RAC2 GTPase cycle"
        },
        {
            "id": "R-DDI-9013407",
            "name": "RHOH GTPase cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013407",
            "resource": "Reactome",
            "description": "RHOH GTPase cycle"
        },
        {
            "id": "R-DDI-9013408",
            "name": "RHOG GTPase cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013408",
            "resource": "Reactome",
            "description": "RHOG GTPase cycle"
        },
        {
            "id": "R-DDI-9013418",
            "name": "RHOBTB2 GTPase cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013418",
            "resource": "Reactome",
            "description": "RHOBTB2 GTPase cycle"
        },
        {
            "id": "R-DDI-9013422",
            "name": "RHOBTB1 GTPase cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9013422",
            "resource": "Reactome",
            "description": "RHOBTB1 GTPase cycle"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 11,
                "go_terms": [
                    {
                        "name": "sexual reproduction",
                        "id": "GO:0019953",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019953",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "actin filament organization",
                        "id": "GO:0007015",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "signal transduction",
                        "id": "GO:0007165",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of actin cytoskeleton organization",
                        "id": "GO:0032956",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "small GTPase mediated signal transduction",
                        "id": "GO:0007264",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of cell shape",
                        "id": "GO:0008360",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitotic cytokinesis",
                        "id": "GO:0000281",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "engulfment of apoptotic cell",
                        "id": "GO:0043652",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "establishment or maintenance of cell polarity",
                        "id": "GO:0007163",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cortical cytoskeleton organization",
                        "id": "GO:0030865",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to imidacloprid",
                        "id": "GO:1902351",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902351",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 8,
                "go_terms": [
                    {
                        "name": "phagocytic cup",
                        "id": "GO:0001891",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell cortex",
                        "id": "GO:0005938",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasmic vesicle",
                        "id": "GO:0031410",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "macropinosome",
                        "id": "GO:0044354",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044354",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell projection",
                        "id": "GO:0042995",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "GTPase activity",
                        "id": "GO:0003924",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "GTP binding",
                        "id": "GO:0005525",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O96390",
                                "url": "https://www.uniprot.org/uniprot/O96390"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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