{
    "uniprot_canonical_ac": "O96099-1",
    "uniprot_ac": "O96099",
    "uniprot_id": "FAD5B_DICDI",
    "mass": {
        "chemical_mass": 54463.0,
        "monoisotopic_mass": 54463.0
    },
    "refseq": {
        "ac": "XP_640331",
        "name": "delta 5 fatty acid desaturase",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640331"
    },
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            "name": "Delta(5) fatty acid desaturase B",
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            "id": "O96099"
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            "id": "XP_640331"
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            "annotation": "Fatty acid desaturase that introduces a cis double bond at the 5-position in 18-carbon polyunsaturated fatty acids.",
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    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Dictyostelium discoideum",
            "taxid": 44689,
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            "common_name": "Cellular slime molds"
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            "url": "https://www.uniprot.org/uniprot/O96099",
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            "id": "cd03506",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03506",
            "database": "CDD",
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        },
        {
            "id": "DDB_G0282147",
            "url": "http://dictybase.org/gene/DDB_G0282147",
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        {
            "id": "8623432",
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            "categories": [
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        {
            "id": "IPR001199",
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            "database": "InterPro",
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        },
        {
            "id": "IPR005804",
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        {
            "id": "IPR012171",
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        {
            "id": "IPR036400",
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        },
        {
            "id": "QHRYWPL",
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            "database": "OMA",
            "categories": [
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        },
        {
            "id": "PTHR19353",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19353",
            "database": "PANTHER",
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        },
        {
            "id": "PTHR19353:SF80",
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            "database": "PANTHER",
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        },
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            "id": "PF00173",
            "url": "http://pfam.xfam.org/family/PF00173",
            "database": "Pfam",
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        },
        {
            "id": "PF00487",
            "url": "http://pfam.xfam.org/family/PF00487",
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            ]
        },
        {
            "id": "PR_O96099",
            "url": "http://purl.obolibrary.org/obo/PR_O96099",
            "database": "PRO",
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        },
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            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640331",
            "database": "RefSeq",
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        },
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            "id": "46260",
            "url": "https://www.rhea-db.org/rhea/46260",
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        },
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            "id": "46264",
            "url": "https://www.rhea-db.org/rhea/46264",
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            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "O96099",
            "url": "https://www.uniprot.org/uniprot/O96099",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "O96099-1",
            "url": "https://www.uniprot.org/uniprot/O96099-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MMETNNENKEKLKLYTWDEVSKHNQKNDLWIIVDGKVYNITKWVPLHPGGEDILLLSAGRDATNLFESYHPMTDKHYSLIKQYEIGYISSYEHPKYVEKSEFYSTLKQRVRKHFQTSSQDPKVSVGVFTRMVLIYLFLFVTYYLSQFSTDRFWLNCIFAVLYGVANSLFGLHTMHDACHTAITHNPMTWKILGATFDLFAGASFYAWCHQHVIGHHLYTNVRNADPDLGQGEIDFRVVTPYQARSWYHKYQHIYAPILYGVYALKYRIQDHEIFTKKSNGAIRYSPISTIDTAIFILGKLVFIISRFILPLIYNHSFSHLICFFLISELVLGWYLAISFQVSHVVEDLQFMATPEIFDGADHPLPTTFNQDWAILQVKTTQDYAQDSVLSTFFSGGLNLQVIHHCFPTIAQDYYPQIVPILKEVCKEYNVTYHYKPTFTEAIKSHINYLYKMGNDPDYVRKPVNKND",
        "length": 467,
        "header": "sp|O96099-1|FAD5B_DICDI Isoform 1 of Acyl-lipid (8-3)-desaturase B  OS=Dictyostelium discoideum OX=44689 GN=fadB PE=1 SV=1 CANONICAL=O96099-1"
    },
    "isoforms": [
        {
            "isoform_ac": "O96099-1",
            "url": "",
            "sequence": {
                "sequence": "MMETNNENKEKLKLYTWDEVSKHNQKNDLWIIVDGKVYNITKWVPLHPGGEDILLLSAGRDATNLFESYHPMTDKHYSLIKQYEIGYISSYEHPKYVEKSEFYSTLKQRVRKHFQTSSQDPKVSVGVFTRMVLIYLFLFVTYYLSQFSTDRFWLNCIFAVLYGVANSLFGLHTMHDACHTAITHNPMTWKILGATFDLFAGASFYAWCHQHVIGHHLYTNVRNADPDLGQGEIDFRVVTPYQARSWYHKYQHIYAPILYGVYALKYRIQDHEIFTKKSNGAIRYSPISTIDTAIFILGKLVFIISRFILPLIYNHSFSHLICFFLISELVLGWYLAISFQVSHVVEDLQFMATPEIFDGADHPLPTTFNQDWAILQVKTTQDYAQDSVLSTFFSGGLNLQVIHHCFPTIAQDYYPQIVPILKEVCKEYNVTYHYKPTFTEAIKSHINYLYKMGNDPDYVRKPVNKND",
                "length": 467,
                "header": "sp|O96099-1|FAD5B_DICDI Isoform 1 of Acyl-lipid (8-3)-desaturase B  OS=Dictyostelium discoideum OX=44689 GN=fadB PE=1 SV=1 CANONICAL=O96099-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "A second functional delta5 fatty acid desaturase in the cellular slime mould Dictyostelium discoideum.",
            "journal": "European journal of biochemistry",
            "date": "2000-03",
            "authors": "Saito T, Morio T, Ochiai H",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96099",
                    "url": "https://www.uniprot.org/uniprot/O96099"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10712614",
                    "url": "https://glygen.org/publication/PubMed/10712614"
                }
            ]
        },
        {
            "title": "Temperature adaptation in Dictyostelium: role of Delta5 fatty acid desaturase.",
            "journal": "Microbiology",
            "date": "2005",
            "authors": "Saito Tamao, Kato Atsushi, Ochiai Hiroshi, Morita Naoki",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O96099",
                    "url": "https://www.uniprot.org/uniprot/O96099"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15632431",
                    "url": "https://glygen.org/publication/PubMed/15632431"
                }
            ]
        },
        {
            "title": "The genome of the social amoeba Dictyostelium discoideum.",
            "journal": "Nature",
            "date": "2005",
            "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A",
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "O96099",
                    "url": "https://www.uniprot.org/uniprot/O96099"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15875012",
                    "url": "https://glygen.org/publication/PubMed/15875012"
                }
            ]
        },
        {
            "title": "Isolation and characterization of genes from the marine microalga Pavlova salina encoding three front-end desaturases involved in docosahexaenoic acid biosynthesis.",
            "journal": "Phytochemistry",
            "date": "2007",
            "authors": "Zhou Xue-Rong, Robert Stanley S, Petrie James R, Frampton Dion M F, Mansour Maged P, Blackburn Susan I, Nichols Peter D, Green Allan G, Singh Surinder P",
            "evidence": [
                {
                    "database": "UniProtKB",
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                    "url": "https://www.uniprot.org/uniprot/O96099"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17291553",
                    "url": "https://glygen.org/publication/PubMed/17291553"
                }
            ]
        }
    ],
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        {
            "id": "ddi:DDB_G0282147",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0282147",
            "resource": "KEGG Pathway"
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    ],
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                "name": "Cellular Component",
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                ]
            },
            {
                "name": "Biological Process",
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                        "name": "lipid metabolic process",
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                                "url": "https://www.uniprot.org/uniprot/O96099"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "unsaturated fatty acid biosynthetic process",
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                        "evidence": [
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                                "id": "O96099",
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                            }
                        ],
                        "pmid": ""
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                ]
            },
            {
                "name": "Molecular Function",
                "total": 4,
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                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
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                        ],
                        "pmid": ""
                    },
                    {
                        "name": "oxidoreductase activity",
                        "id": "GO:0016491",
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                                "id": "O96099",
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                        "pmid": ""
                    },
                    {
                        "name": "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water",
                        "id": "GO:0016717",
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                                "id": "O96099",
                                "url": "https://www.uniprot.org/uniprot/O96099"
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                    },
                    {
                        "name": "di-homo-gamma-linolenate delta5 desaturase activity",
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                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "O96099",
                                "url": "https://www.uniprot.org/uniprot/O96099"
                            }
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            "end_pos": 316,
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            "id": "46260",
            "name": "",
            "equation": "an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
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            "summary": "",
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