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"" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "O95302", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O95302" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, intestinal", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ] } ] }, { "significant": "No", "trend": "down", "name": "Urinary bladder cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "O95302", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O95302" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": 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"name": "Colorectal cancer", "description": "Colorectal cancer" } ] } ] } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "common_name": "Human" } ], "gene": [ { "name": "FKBP9", "url": "https://www.uniprot.org/uniprot/O95302", "locus": { "chromosome": "7", "start_pos": 33006930, "end_pos": 32957404, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSG00000122642", "url": "https://www.ensembl.org/id/ENSG00000122642" } ] } } ], "crossref": [ { "id": "ENSG00000122642", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000122642", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "O95302", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O95302", "database": "BioMuta", "categories": [ "Variation" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FKBP9", "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=FKBP9", "database": "GeneCards", "categories": [ "Gene Annotation", "Organism-specific" ] }, { "id": "11328", "url": "https://www.ncbi.nlm.nih.gov/gene/11328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "1598", "url": "https://glyconnect.expasy.org/browser/proteins/1598", "database": "GlyConnect", "categories": [ "Glycoproteomics", "Glycan" ] }, { "id": "3725", "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3725", "database": "HGNC", "categories": [ "Organism-specific" ] }, { "id": "O95302", "url": "https://www.ebi.ac.uk/intact/interactors/id:O95302*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "hsa:11328", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:11328", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "616257", "url": "http://www.omim.org/entry/616257", "database": "MIM", "categories": [ "Other" ] }, { "id": "NX_O95302", "url": "https://www.nextprot.org/entry/NX_O95302", "database": "neXtProt", "categories": [ "Protein", "Organism-specific" ] }, { "id": "O95302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O95302", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "YYKPENC", "url": "https://omabrowser.org/oma/group/YYKPENC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "25281at2759", "url": "http://www.orthodb.org/?query=25281at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46046:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46046:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "http://pfam.xfam.org/family/PF00254", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "O95302", "url": "https://pharos.nih.gov/targets/O95302", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR:000050898", "url": "https://proconsortium.org/app/entry/PR:000050898", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR_O95302", "url": "http://purl.obolibrary.org/obo/PR_O95302", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001271270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001271270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "O95302", "url": "DISABLED", "database": "UniCarbKB", "categories": [ "Glycoproteomics" ] }, { "id": "C9J4P8", "url": "https://www.uniprot.org/uniprot/C9J4P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C9J4P8-1", "url": "https://www.uniprot.org/uniprot/C9J4P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O95302-1", "url": "https://www.uniprot.org/uniprot/O95302-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O95302-2", "url": "https://www.uniprot.org/uniprot/O95302-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O95302-3", "url": "https://www.uniprot.org/uniprot/O95302-3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL", "length": 570, "header": "sp|O95302-1|FKBP9_HUMAN Isoform 1 of Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens OX=9606 GN=FKBP9 PE=1 SV=2 CANONICAL=O95302-1" }, "isoforms": [ { "isoform_ac": "C9J4P8-1", "url": "", "sequence": { "sequence": "MAGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGV", "length": 225, "header": "tr|C9J4P8-1|FKBP9_HUMAN Computationally mapped isoform of Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens OX=9606 GN=FKBP9 PE=1 SV=8 CANONICAL=O95302-1" }, "locus": { "chromosome": "7", "start_pos": 33000259, "end_pos": 32979577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000418354.5", "url": "https://www.ensembl.org/id/ENST00000418354.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000391034.1", "url": "https://www.ensembl.org/id/ENSP00000391034.1" } ] } }, { "isoform_ac": "O95302-1", "url": "", "sequence": { "sequence": "MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL", "length": 570, "header": "sp|O95302-1|FKBP9_HUMAN Isoform 1 of Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens OX=9606 GN=FKBP9 PE=1 SV=2 CANONICAL=O95302-1" }, "locus": { "chromosome": "7", "start_pos": 33005348, "end_pos": 32957574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000242209.9", "url": "https://www.ensembl.org/id/ENST00000242209.9" }, { "database": "Ensembl Peptide", "id": "ENSP00000242209.4", "url": "https://www.ensembl.org/id/ENSP00000242209.4" } ] } }, { "isoform_ac": "O95302-2", "url": "", "sequence": { "sequence": "MAGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL", "length": 338, "header": "sp|O95302-2|FKBP9_HUMAN Isoform 2 of Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens OX=9606 GN=FKBP9 PE=1 SV=2 CANONICAL=O95302-1" }, "locus": { "chromosome": "7", "start_pos": 33005348, "end_pos": 32979577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000490776.3", "url": "https://www.ensembl.org/id/ENST00000490776.3" }, { "database": "Ensembl Peptide", "id": "ENSP00000441317.1", "url": "https://www.ensembl.org/id/ENSP00000441317.1" } ] } }, { "isoform_ac": "O95302-3", "url": "", "sequence": { "sequence": "MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSRYWDTAEDKADKSPCPQVRVGVNTSPSCRLKQKGVGIYWKDLQFLVRVQNHGLSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL", "length": 623, "header": "sp|O95302-3|FKBP9_HUMAN Isoform 3 of Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens OX=9606 GN=FKBP9 PE=1 SV=2 CANONICAL=O95302-1" }, "locus": { "chromosome": "7", "start_pos": 33005348, "end_pos": 32957574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000538336.5", "url": "https://www.ensembl.org/id/ENST00000538336.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000439250.1", "url": "https://www.ensembl.org/id/ENSP00000439250.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "O95302@N174", "database": "GPTwiki", "url": "https://edwardslab.bmcb.georgetown.edu/gptwiki/O95302@N174" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "O95302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95302#ptm_processing" }, { "id": "12754519", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12754519" } ] }, { "glytoucan_ac": "G01650EU", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "O95302", "database": "UniCarbKB", "url": "" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G23294PN", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G25079LO", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "O95302@N286", "database": "GPTwiki", "url": "https://edwardslab.bmcb.georgetown.edu/gptwiki/O95302@N286" } ] }, { "glytoucan_ac": "G48584BU", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G66621EA", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "O95302@N286", "database": "GPTwiki", "url": "https://edwardslab.bmcb.georgetown.edu/gptwiki/O95302@N286" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "O95302", "database": "UniCarbKB", "url": "" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" }, { "id": "O95302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95302#ptm_processing" }, { "id": "12754519", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12754519" }, { "id": "24190977", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24190977" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 302, "start_aa": "Asn", "end_pos": 302, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn302", "evidence": [ { "id": "O95302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95302#ptm_processing" } ] }, { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 397, "start_aa": "Asn", "end_pos": 397, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn397", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 397, "start_aa": "Asn", "end_pos": 397, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn397", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 397, "start_aa": "Asn", "end_pos": 397, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn397", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 397, "start_aa": "Asn", "end_pos": 397, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn397", "evidence": [ { "id": "1598", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/1598" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 397, "start_aa": "Asn", "end_pos": 397, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn397", "evidence": [ { "id": "O95302", "database": "UniCarbKB", "url": "" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" }, { "id": "O95302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95302#ptm_processing" }, { "id": "12754519", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12754519" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "O95302", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O95302" }, { "id": "34019948", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34019948" }, { "id": "34725712", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34725712" }, { "id": "33214551", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33214551" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_reported", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "Biochemical analysis of mouse FKBP60, a novel member of the FKBP family.", "journal": "Biochim. Biophys. Acta", "date": "1999", "authors": "Shadidy M, Caubit X, Olsen R, Seternes OM, Moens U, Krauss S", "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "reference": [ { "type": "PubMed", "id": "10524204", "url": "https://glygen.org/publication/PubMed/10524204" } ] }, { "title": "Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex.", "journal": "Genes & development", "date": "2002", "authors": "Guenther MG, Yu J, Kao GD, Yen TJ, Lazar MA", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "12502735", "url": "https://glygen.org/publication/PubMed/12502735" } ] }, { "title": "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.", "journal": "Nature biotechnology", "date": "2003", "authors": "Zhang H, Li XJ, Martin DB, Aebersold R", "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302#ptm_processing" }, { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "reference": [ { "type": "PubMed", "id": "12754519", "url": "https://glygen.org/publication/PubMed/12754519" } ] }, { "title": "The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1.", "journal": "The international journal of biochemistry & cell biology", "date": "2009", "authors": "Zebol JR, Hewitt NM, Moretti PA, Lynn HE, Lake JA, Li P, Vadas MA, Wattenberg BW, Pitson SM", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "18775504", "url": "https://glygen.org/publication/PubMed/18775504" } ] }, { "title": "Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies.", "journal": "Nature structural & molecular biology", "date": "2008", "authors": "Yam AY, Xia Y, Lin HT, Burlingame A, Gerstein M, Frydman J", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "19011634", "url": "https://glygen.org/publication/PubMed/19011634" } ] }, { "title": "Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2010", "authors": "Lu J, Chiang J, Iyer RR, Thompson E, Kaneski CR, Xu DS, Yang C, Chen M, Hodes RJ, Lonser RR, Brady RO, Zhuang Z", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "21098288", "url": "https://glygen.org/publication/PubMed/21098288" } ] }, { "title": "Chaperonin TRiC assists the refolding of sperm-specific glyceraldehyde-3-phosphate dehydrogenase.", "journal": "Archives of biochemistry and biophysics", "date": "2011", "authors": "Naletova IN, Popova KM, Eldarov MA, Kuravsky ML, Schmalhausen EV, Sevostyanova IA, Muronetz VI", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "21995946", "url": "https://glygen.org/publication/PubMed/21995946" } ] }, { "title": "Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.", "journal": "Cell", "date": "2012", "authors": "Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, Choi K, de Waal L, Sharifnia T, Brooks A, Greulich H, Banerji S, Zander T, Seidel D, Leenders F, Ansen S, Ludwig C, Engel-Riedel W, Stoelben E, Wolf J, Goparju C, Thompson K, Winckler W, Kwiatkowski D, Johnson BE, Janne PA, Miller VA, Pao W, Travis WD, Pass HI, Gabriel SB, Lander ES, Thomas RK, Garraway LA, Getz G, Meyerson M", "evidence": [ { "database": "dbSNP", "id": "rs758124189", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs758124189" } ], "reference": [ { "type": "PubMed", "id": "22980975", "url": "https://glygen.org/publication/PubMed/22980975" } ] }, { "title": "Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity.", "journal": "Molecular cell", "date": "2013", "authors": "Trinidad AG, Muller PA, Cuellar J, Klejnot M, Nobis M, Valpuesta JM, Vousden KH", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "23747015", "url": "https://glygen.org/publication/PubMed/23747015" } ] }, { "title": "N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes.", "journal": "Molecular & cellular proteomics : MCP", "date": "2014", "authors": "Deeb SJ, Cox J, Schmidt-Supprian M, Mann M", "evidence": [ { "database": "GlyGen", "id": "GLY_000143", "url": "https://data.glygen.org/GLY_000143" } ], "reference": [ { "type": "PubMed", "id": "24190977", "url": "https://glygen.org/publication/PubMed/24190977" } ] }, { "title": "Modulation of STAT3 folding and function by TRiC/CCT chaperonin.", "journal": "PLoS biology", "date": "2014", "authors": "Kasembeli M, Lau WC, Roh SH, Eckols TK, Frydman J, Chiu W, Tweardy DJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "24756126", "url": "https://glygen.org/publication/PubMed/24756126" } ] }, { "title": "The molecular chaperone TRiC/CCT binds to the Trp-Asp 40 (WD40) repeat protein WDR68 and promotes its folding, protein kinase DYRK1A binding, and nuclear accumulation.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Miyata Y, Shibata T, Aoshima M, Tsubata T, Nishida E", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "25342745", "url": "https://glygen.org/publication/PubMed/25342745" } ] }, { "title": "Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.", "journal": "Cell", "date": "2014", "authors": "Freund A, Zhong FL, Venteicher AS, Meng Z, Veenstra TD, Frydman J, Artandi SE", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "25467444", "url": "https://glygen.org/publication/PubMed/25467444" } ] }, { "title": "Reanalysis of Global Proteomic and Phosphoproteomic Data Identified a Large Number of Glycopeptides.", "journal": "Analytical chemistry", "date": "2018", "authors": "Hu Y, Shah P, Clark DJ, Ao M, Zhang H", "evidence": [ { "database": "UniCarbKB", "id": "O95302", "url": "" }, { "database": "GlyConnect", "id": "1598", "url": "https://glyconnect.expasy.org/browser/proteins/1598" } ], "reference": [ { "type": "PubMed", "id": "29741879", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "title": "Increasing of FKBP9 can predict poor prognosis in patients with prostate cancer.", "journal": "Pathology, research and practice", "date": "2020", "authors": "Jiang FN, Dai LJ, Yang SB, Wu YD, Liang YX, Yin XL, Zou CY, Zhong WD", "evidence": [ { "database": "RefSeq", "id": "NP_001271270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001271270" } ], "reference": [ { "type": "PubMed", "id": "31780055", "url": "https://glygen.org/publication/PubMed/31780055" } ] }, { "title": "FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.", "journal": "Journal of experimental & clinical cancer research : CR", "date": "2020", "authors": "Xu H, Liu P, Yan Y, Fang K, Liang D, Hou X, Zhang X, Wu S, Ma J, Wang R, Li T, Piao H, Meng S", "evidence": [ { "database": "RefSeq", "id": "NP_001271270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001271270" } ], "reference": [ { "type": "PubMed", "id": "32111229", "url": "https://glygen.org/publication/PubMed/32111229" } ] }, { "title": "Proteomic profiling and genome-wide mapping of O-GlcNAc chromatin-associated proteins reveal an O-GlcNAc-regulated genotoxic stress response.", "journal": "Nature communications", "date": "2020", "authors": "Liu Y, Chen Q, Zhang N, Zhang K, Dou T, Cao Y, Liu Y, Li K, Hao X, Xie X, Li W, Ren Y, Zhang J", "evidence": [ { "database": "O-GlcNAc Database", "id": "O95302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O95302" } ], "reference": [ { "type": "PubMed", "id": "33214551", "url": "https://glygen.org/publication/PubMed/33214551" } ] }, { "title": "O-GlcNAc modification regulates MTA1 transcriptional activity during breast cancer cell genotoxic adaptation.", "journal": "Biochimica et biophysica acta. General subjects", "date": "2021", "authors": "Xie X, Wu Q, Zhang K, Liu Y, Zhang N, Chen Q, Wang L, Li W, Zhang J, Liu Y", "evidence": [ { "database": "O-GlcNAc Database", "id": "O95302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O95302" } ], "reference": [ { "type": "PubMed", "id": "34019948", "url": "https://glygen.org/publication/PubMed/34019948" } ] }, { "title": "Truncation of the TPR domain of OGT alters substrate and glycosite selection.", "journal": "Analytical and bioanalytical chemistry", "date": "2021", "authors": "Ramirez DH, Yang B, D'Souza AK, Shen D, Woo CM", "evidence": [ { "database": "O-GlcNAc Database", "id": "O95302", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O95302" } ], "reference": [ { "type": "PubMed", "id": "34725712", "url": "https://glygen.org/publication/PubMed/34725712" } ] }, { "title": "Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Won KA, Schumacher RJ, Farr GW, Horwich AL, Reed SI", "evidence": [ { "database": "Reactome", "id": "R-HSA-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471" } ], "reference": [ { "type": "PubMed", "id": "9819444", "url": "https://glygen.org/publication/PubMed/9819444" } ] } ], "pathway": [ { "id": "hsa:11328", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:11328", "resource": "KEGG Pathway" }, { "id": "R-HSA-390471", "name": "Association of TriC/CCT with target proteins during biosynthesis", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390471", "resource": "Reactome", "description": "Association of TriC/CCT with target proteins during biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "Q66H94-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP9", "gene_name": "Fkbp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFGARGWRRWSLLLLLLWVTGQAAPVLGLAVSSELQIQRSFVPDECPRTVRSGDFVRYHYVGTFLDGQKFDSSYDRDSTFSVFVGKGQLIAGMDQALVGMCVNERRFVTIPPNLAYGSEGVSGVIPPNSVLHFDVLLVDIWNSEDQVQIQTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEEGDGKDIPGQASLVFDVALLDLHNPKDTISVENKVVPESCERRSQSGDFLRYHYNGTLLDGTLFDSSYSRNHTFDTYIGQGYVIPGMDEGLLGVCIGERRRIVVPPHLGYGEEGRGSIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGFGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVSGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFNAEMIVKNMFTNQDRNGDGKVTAEEFKLKDQETKHDEL", "length": 570 }, "evidence": [ { "id": "45925552", "url": "http://www.informatics.jax.org/homology/45925552", "database": "MGI" }, { "id": "O95302", "url": "https://omabrowser.org/oma/group/O95302/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z247-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP9", "gene_name": "Fkbp9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGARGWRRRSLLLLLLWVTGQAAPVLGLAVSSELQIQQSFVPDECPRTVHSGDFVRYHYVGTFLDGQKFDSSYDRDSTFNVFVGKGQLIAGMDQALVGMCVNERRLVTIPPNLAYGSEGVSGVIPPNSVLHFDVLLVDIWNSEDQVHIQTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITVPPFLAYGEEGDGKDIPGQASLVFDVALLDLHNPKDTISIENKVVPENCERRSQSGDFLRYHYNGTLLDGTLFDSSYSRNHTFDTYIGQGYVIPGMDEGLLGVCIGERRRIVVPPHLGYGEKGRGSIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVSGLPEGYMFIWNGEVSPNLFEEIDRDGNGEVLLEEFSEYIHAQVATGKGKLAPGFNAEMIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL", "length": 570 }, "evidence": [ { "id": "45925552", "url": "http://www.informatics.jax.org/homology/45925552", "database": "MGI" }, { "id": "O95302", "url": "https://omabrowser.org/oma/group/O95302/", "database": "OMA" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "O95302", "url": "https://www.uniprot.org/uniprot/O95302" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "peptidyl-prolyl cis-trans isomerase FKBP9 N-glycosylated 1 (human)", "definition": "A peptidyl-prolyl cis-trans isomerase FKBP9 (human) that has been N-glycosylated at the residue equivalent to Asn-286 of the amino acid sequence represented by UniProtKB:O95302-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:O95302-1, Asn-286, MOD:00160~GNO:G01650EU. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000050898", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050898" } ] } ], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8I6GKI8-1", "P24368-1", "Q9QVC8-1", "P97534-1", "Q3B7U9-1", "Q66H94-1", "Q62658-1", "Q812D3-1", "O55035-1", "Q6DGG0-1", "P10111-1", "P29117-1", "Q5U2V1-1", "A0A8I6GGK9-1", "A0A8I6AE14-1", "G3V7V5-1", "G3V6L9-1", "A0A8I6GH88-1", "A0A8I6A7U0-1", "D4AEG3-1", "A0A0G2K869-1", "M0RCZ9-1", "Q4KLI4-1", "A0A8I5ZMT9-1", "Q6AYQ9-1", "A0A8I5ZR77-1", "A0A8I5ZPZ9-1", "A0A8I6A7W4-1", "A0A8I6A3L4-1", "A0A8I6GJ67-1", "A0A8I6AK73-1", "A0A8I6GE67-1", "A0A8I6GB94-1", "A0A8I6AFJ6-1", "D3ZQF4-1", "A0A8I5ZVA3-1", "A0A8I6A629-1", "A0A8I6AP42-1", "A0A8I5Y1J2-1", "F7EYK0-1", "A0A8I6AIC0-1", "A0A8I6ADW5-1", "A6K0V4-1", "Q14318-1", "Q5VVH2-1", "O75344-1", "O00170-1", "Q96AY3-1", "O95302-1", "P0DN26-1", "P68106-1", "Q02790-1", "Q15257-1", "Q9NYL4-1", "Q9NWM8-1", "P62942-1", "Q13526-1", "P26885-1", "Q00688-1", "Q9Y680-2", "Q13451-1", "P0DN37-1", "A0A075B759-1", "Q9Y536-1", "F5H284-1", "P30414-1", "O43447-1", "Q9H2H8-1", "Q8WUA2-1", "Q9Y237-1", "A0A0B4J2A2-1", "Q08752-1", "P30405-1", "Q9Y3C6-1", "P23284-1", "P62937-1", "Q9UNP9-1", "P45877-1", "Q13427-1", "Q96BP3-1", "Q8IXY8-1", "A0A075B767-1", "Q5T1M5-1", "Q6UX04-1", "Q6P9Q6-1", "Q64378-1", "Q62446-1", "Q3ULQ2-1", "P30416-1", "Q9Z2I2-1", "O35465-1", "O54998-1", "Q9Z247-1", "P45878-1", "Q9D1M7-1", "Q61576-1", "P26883-1", "P59024-1", "Q9CXG3-1", "Q9CWW6-1", "P30415-1", "Q9QUR7-1", "Q9CR16-1", "P58389-1", "Q9D6L8-1", "P17742-1", "P24369-1", "Q8CEC6-1", "A2AR02-1", "P30412-1", "Q9D868-1", "Q9QZH3-1", "Q99KR7-1", "Q9D0W5-1", "Q3TKY6-1", "Q9D6D8-1", "P14832-1", "P20081-1", "P25719-1", "P40454-1", "Q12461-1", "P22696-1", "P47103-1", "P53691-1", "Q06205-1", "P32472-1", "P25334-1", "P23285-1", "P35176-1", "P38911-1", "P53728-1", "Q02770-1", "Q54E95-1", "Q54LG6-1", "Q54RW5-1", "Q54Z53-1", "Q554J3-1", "Q54CU3-1", "Q54G21-1", "Q54N80-1", "Q54NB6-1", "Q54SR7-1", "Q54WH6-1", "Q54Y27-1", "Q55CJ3-1", "Q86J17-1", "Q55EZ0-1", "B0G119-1", "Q54QI6-1", "Q54UR2-1", "Q9UA41-1", "Q54SM3-1", "Q9NI62-1", "Q9TW32-1", "P25007-1", "Q9V3G3-1", "P15425-1", "P54353-1", "P54397-1", "P48375-1", "Q9VL78-1", "A0A0B4K7C5-1", "Q4V5H1-1", "Q9VQQ0-1", "Q7K2I4-1", "Q8MKJ6-1", "Q9VNG7-1", "Q9VXN8-1", "Q9VGK3-1", "Q9VBU4-1", "Q9XYZ6-1", "Q9W227-1", "Q9W0Q2-1", "Q7K3D4-1", "Q8IRJ5-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-HSA-390470", "name": "Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone)", "equation": "", "summary": "A combination of proteomic and bioinformatics analyses of TRiC substrates has revealed that they have complex topologies that are slow folding and aggregation prone (Yam et al., 2008). These substrates are also enriched in proteins that belong to oligomeric assemblies suggesting that TRiC plays a role in promoting complex assembly (Yam et al., 2008). Two possible mechanisms describing the role of TriC have been suggested (Yam et al., 2008). The processes of TRiC-mediated folding and assembly could be directly coupled, or TRiC could fold monomeric subunits and hold them in an assembly-competent state until they associate with the appropriate partner subunits. The complete list of TriC subsrates is not yet known. Many of its substrates that are targeted during biosynthesis are conserved between mammals and yeast (Yam et al. 2008).", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q15477-1", "O95302-1", "O15379-1", "Q86WA8-1", "P51784-1", "Q9H0D6-1", "O14556-1", "P04062-1" ], "evidence": [ { "id": "R-HSA-390470", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-390470" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A075B759", "gene_name": "PPIAL4E", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A075B759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A075B759" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A075B759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A075B759" } ] } ] }, { "uniprot_ac": "A0A075B767", "gene_name": "PPIAL4H", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A075B767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A075B767" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A075B767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A075B767" } ] } ] }, { "uniprot_ac": "A0A0B4J2A2", "gene_name": "PPIAL4C", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A0B4J2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4J2A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A0B4J2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4J2A2" } ] } ] }, { "uniprot_ac": "A0A0B4K7C5", "gene_name": "Fkbp14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A0B4K7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4K7C5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A0B4K7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4K7C5" } ] } ] }, { "uniprot_ac": "A0A0G2K869", "gene_name": "AABR07056556.1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A0G2K869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K869" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A0G2K869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K869" } ] } ] }, { "uniprot_ac": "A0A8I5Y1J2", "gene_name": "ENSRNOG00000067128", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I5Y1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y1J2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I5Y1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y1J2" } ] } ] }, { "uniprot_ac": "A0A8I5ZMT9", "gene_name": "Ppih", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I5ZMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMT9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I5ZMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMT9" } ] } ] }, { "uniprot_ac": "A0A8I5ZPZ9", "gene_name": "Ptpa", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I5ZPZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPZ9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I5ZPZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZPZ9" } ] } ] }, { "uniprot_ac": "A0A8I5ZR77", "gene_name": "ENSRNOG00000071104", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I5ZR77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR77" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I5ZR77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR77" } ] } ] }, { "uniprot_ac": "A0A8I5ZVA3", "gene_name": "ENSRNOG00000068459", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I5ZVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZVA3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I5ZVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZVA3" } ] } ] }, { "uniprot_ac": "A0A8I6A3L4", "gene_name": "ENSRNOG00000067890", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6A3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A3L4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6A3L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A3L4" } ] } ] }, { "uniprot_ac": "A0A8I6A629", "gene_name": "LOC100911252", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6A629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A629" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6A629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A629" } ] } ] }, { "uniprot_ac": "A0A8I6A7U0", "gene_name": "Fkbp15", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6A7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7U0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6A7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7U0" } ] } ] }, { "uniprot_ac": "A0A8I6A7W4", "gene_name": "ENSRNOG00000062802", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6A7W4", "database": "UniProtKB", "url": 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] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6AE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AE14" } ] } ] }, { "uniprot_ac": "A0A8I6AFJ6", "gene_name": "ENSRNOG00000068575", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6AFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AFJ6" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6AFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AFJ6" } ] } ] }, { "uniprot_ac": "A0A8I6AIC0", "gene_name": "ENSRNOG00000066761", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6AIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AIC0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6AIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AIC0" } ] } ] }, { "uniprot_ac": "A0A8I6AK73", "gene_name": "ENSRNOG00000065084", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6AK73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AK73" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6AK73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AK73" } ] } ] }, { "uniprot_ac": "A0A8I6AP42", "gene_name": "Ppia-ps13", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6AP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AP42" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6AP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AP42" } ] } ] }, { "uniprot_ac": "A0A8I6GB94", "gene_name": "Nktr", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6GB94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GB94" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6GB94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GB94" } ] } ] }, { "uniprot_ac": "A0A8I6GE67", "gene_name": "ENSRNOG00000063066", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6GE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GE67" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6GE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GE67" } ] } ] }, { "uniprot_ac": "A0A8I6GGK9", "gene_name": "Ppie", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6GGK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GGK9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6GGK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GGK9" } ] } ] }, { "uniprot_ac": "A0A8I6GH88", "gene_name": "Fkbp2", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6GH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GH88" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6GH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GH88" } ] } ] }, { "uniprot_ac": "A0A8I6GJ67", "gene_name": "Pin1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6GJ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJ67" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6GJ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJ67" } ] } ] }, { "uniprot_ac": "A0A8I6GKI8", "gene_name": "Pin4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8I6GKI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKI8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8I6GKI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKI8" } ] } ] }, { "uniprot_ac": "A2AR02", "gene_name": "Ppig", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A2AR02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AR02" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A2AR02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AR02" } ] } ] }, { "uniprot_ac": "A6K0V4", "gene_name": "Fkbp14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A6K0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K0V4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A6K0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K0V4" } ] } ] }, { "uniprot_ac": "B0G119", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "B0G119", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G119" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "B0G119", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G119" } ] } ] }, { "uniprot_ac": "D3ZQF4", "gene_name": "Fkbp6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "D3ZQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQF4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "D3ZQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQF4" } ] } ] }, { "uniprot_ac": "D4AEG3", "gene_name": "Ppil4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "D4AEG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AEG3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "D4AEG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AEG3" } ] } ] }, { "uniprot_ac": "F5H284", "gene_name": "PPIAL4D", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F5H284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F5H284" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F5H284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F5H284" } ] } ] }, { "uniprot_ac": "F7EYK0", "gene_name": "Fkbp5", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F7EYK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7EYK0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F7EYK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7EYK0" } ] } ] }, { "uniprot_ac": "G3V6L9", "gene_name": "Fkbp3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "G3V6L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6L9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "G3V6L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6L9" } ] } ] }, { "uniprot_ac": "G3V7V5", "gene_name": "Fkbp11", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "G3V7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V7V5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "G3V7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V7V5" } ] } ] }, { "uniprot_ac": "M0RCZ9", "gene_name": "Ppial4g", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "M0RCZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RCZ9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "M0RCZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RCZ9" } ] } ] }, { "uniprot_ac": "O00170", "gene_name": "AIP", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O00170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00170" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O00170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00170" } ] } ] }, { "uniprot_ac": "O14556", "gene_name": "GAPDHS", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "O14556", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14556" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "O14556", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14556" } ] } ] }, { "uniprot_ac": "O15379", "gene_name": "HDAC3", "activity": [ { "ec_number": "3.5.1.98", "activity": "H2O + N(6)-acetyl-L-lysyl-[histone] = acetate + L-lysyl-[histone].", "evidence": [ { "id": "O15379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15379" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "O15379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15379" } ] }, { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "O15379", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15379" } ] } ] }, { "uniprot_ac": "O35465", "gene_name": "Fkbp8", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35465" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35465" } ] } ] }, { "uniprot_ac": "O43447", "gene_name": "PPIH", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O43447", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43447" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O43447", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43447" } ] } ] }, { "uniprot_ac": "O54998", "gene_name": "Fkbp7", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O54998", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54998" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O54998", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54998" } ] } ] }, { "uniprot_ac": "O55035", "gene_name": "Ppig", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O55035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55035" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O55035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55035" } ] } ] }, { "uniprot_ac": "O75344", "gene_name": "FKBP6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O75344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75344" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O75344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75344" } ] } ] }, { "uniprot_ac": "O95302", "gene_name": "FKBP9", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O95302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95302" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O95302", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95302" } ] } ] }, { "uniprot_ac": "P04062", "gene_name": "GBA1", "activity": [ { "ec_number": "3.2.1.45", "activity": "a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose.", "evidence": [ { "id": "P04062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04062" } ] }, { "ec_number": "3.2.1.45", "activity": "", "evidence": [ { "id": "P04062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04062" } ] }, { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "P04062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04062" } ] }, { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "P04062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04062" } ] }, { "ec_number": "3.2.1.46", "activity": "a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose.", "evidence": [ { "id": "P04062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04062" } ] } ] }, { "uniprot_ac": "P0DN26", "gene_name": "PPIAL4F", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P0DN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DN26" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P0DN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DN26" } ] } ] }, { "uniprot_ac": "P0DN37", "gene_name": "PPIAL4G", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P0DN37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DN37" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P0DN37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DN37" } ] } ] }, { "uniprot_ac": "P10111", "gene_name": "Ppia", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P10111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10111" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P10111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10111" } ] } ] }, { "uniprot_ac": "P14832", "gene_name": "CPR1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P14832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14832" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P14832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14832" } ] } ] }, { "uniprot_ac": "P15425", "gene_name": "ninaA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P15425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15425" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P15425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15425" } ] } ] }, { "uniprot_ac": "P17742", "gene_name": "Ppia", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P17742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17742" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P17742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17742" } ] } ] }, { "uniprot_ac": "P20081", "gene_name": "FPR1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P20081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20081" } ] } ] }, { "uniprot_ac": "P22696", "gene_name": "ESS1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P22696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22696" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P22696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22696" } ] } ] }, { "uniprot_ac": "P23284", "gene_name": "PPIB", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P23284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23284" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P23284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23284" } ] } ] }, { "uniprot_ac": "P23285", "gene_name": "CPR2", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P23285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23285" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P23285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23285" } ] } ] }, { "uniprot_ac": "P24368", "gene_name": "Ppib", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P24368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24368" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P24368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24368" } ] } ] }, { "uniprot_ac": "P24369", "gene_name": "Ppib", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P24369", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24369" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P24369", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24369" } ] } ] }, { "uniprot_ac": "P25007", "gene_name": "Cyp1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P25007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25007" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P25007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25007" } ] } ] }, { "uniprot_ac": "P25334", "gene_name": "CPR4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P25334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25334" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P25334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25334" } ] } ] }, { "uniprot_ac": "P25719", "gene_name": "CPR3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P25719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25719" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P25719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25719" } ] } ] }, { "uniprot_ac": "P26883", "gene_name": "Fkbp1a", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P26883", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26883" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P26883", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26883" } ] } ] }, { "uniprot_ac": "P26885", "gene_name": "FKBP2", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P26885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26885" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P26885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26885" } ] } ] }, { "uniprot_ac": "P29117", "gene_name": "Ppif", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P29117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29117" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P29117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29117" } ] } ] }, { "uniprot_ac": "P30405", "gene_name": "PPIF", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P30405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30405" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P30405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30405" } ] } ] }, { "uniprot_ac": "P30412", "gene_name": "Ppic", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P30412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30412" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P30412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30412" } ] } ] }, { "uniprot_ac": "P30414", "gene_name": "NKTR", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P30414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30414" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P30414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30414" } ] } ] }, { "uniprot_ac": "P30415", "gene_name": "Nktr", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P30415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30415" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P30415", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30415" } ] } ] }, { "uniprot_ac": "P30416", "gene_name": "Fkbp4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P30416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30416" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P30416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30416" } ] } ] }, { "uniprot_ac": "P32472", "gene_name": "FPR2", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P32472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32472" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P32472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32472" } ] } ] }, { "uniprot_ac": "P35176", "gene_name": "CPR5", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P35176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35176" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P35176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35176" } ] } ] }, { "uniprot_ac": "P38911", "gene_name": "FPR3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P38911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38911" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P38911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38911" } ] } ] }, { "uniprot_ac": "P40454", "gene_name": "RRD1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P40454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40454" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P40454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40454" } ] } ] }, { "uniprot_ac": "P45877", "gene_name": "PPIC", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P45877", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45877" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P45877", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45877" } ] } ] }, { "uniprot_ac": "P45878", "gene_name": "Fkbp2", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P45878", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45878" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P45878", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45878" } ] } ] }, { "uniprot_ac": "P47103", "gene_name": "CPR7", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P47103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47103" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P47103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47103" } ] } ] }, { "uniprot_ac": "P48375", "gene_name": "Fkbp12", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P48375", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48375" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P48375", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48375" } ] } ] }, { "uniprot_ac": "P51784", "gene_name": "USP11", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "P51784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51784" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "P51784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51784" } ] } ] }, { "uniprot_ac": "P53691", "gene_name": "CPR6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P53691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53691" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P53691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53691" } ] } ] }, { "uniprot_ac": "P53728", "gene_name": "CPR8", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P53728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53728" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P53728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53728" } ] } ] }, { "uniprot_ac": "P54353", "gene_name": "dod", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P54353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54353" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P54353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54353" } ] } ] }, { "uniprot_ac": "P54397", "gene_name": "Fkbp39", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P54397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54397" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P54397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54397" } ] } ] }, { "uniprot_ac": "P58389", "gene_name": "Ptpa", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P58389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58389" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P58389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58389" } ] } ] }, { "uniprot_ac": "P59024", "gene_name": "Fkbp14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P59024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59024" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P59024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59024" } ] } ] }, { "uniprot_ac": "P62937", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P62937", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62937" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P62937", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62937" } ] } ] }, { "uniprot_ac": "P62942", "gene_name": "FKBP1A", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P62942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62942" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P62942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62942" } ] } ] }, { "uniprot_ac": "P68106", "gene_name": "FKBP1B", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P68106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68106" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P68106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68106" } ] } ] }, { "uniprot_ac": "P97534", "gene_name": "Fkbp1b", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P97534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97534" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P97534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97534" } ] } ] }, { "uniprot_ac": "Q00688", "gene_name": "FKBP3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q00688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00688" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q00688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00688" } ] } ] }, { "uniprot_ac": "Q02770", "gene_name": "CWC27", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q02770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02770" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q02770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02770" } ] } ] }, { "uniprot_ac": "Q02790", "gene_name": "FKBP4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q02790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02790" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q02790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02790" } ] } ] }, { "uniprot_ac": "Q06205", "gene_name": "FPR4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q06205", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06205" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q06205", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06205" } ] } ] }, { "uniprot_ac": "Q08752", "gene_name": "PPID", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q08752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08752" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q08752", "database": "UniProtKB", "url": 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