{ "uniprot_canonical_ac": "O95298-1", "uniprot_ac": "O95298", "uniprot_id": "NDUC2_HUMAN", "mass": { "chemical_mass": 14188.0, "monoisotopic_mass": 14188.0 }, "refseq": { "ac": "NP_001190983", "name": "NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983" }, "gene_names": [ { "name": "NDUFC2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O95298", "id": "O95298" }, { "name": "B14.5b; CI-B14.5b; HLC-1; MC1DN36; NADHDH2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983", "id": "NP_001190983" }, { "name": "HLC1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O95298", "id": "O95298" }, { "name": "NDUFC2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983", "id": "NP_001190983" } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 subunit C2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O95298" }, { "name": "CI-B14.5b", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O95298" }, { "name": "Complex I-B14.5b", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O95298" }, { "name": "HLC-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O95298" }, { "name": "Human lung cancer oncogene 1 protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O95298" }, { "name": "NADH dehydrogenase [ubiquinone] 1 subunit C2 isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983", "id": "NP_001190983" }, { "name": "NADH-ubiquinone oxidoreductase subunit B14.5b", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O95298" }, { "name": "complex I subunit B14.5b; NADH dehydrogenase [ubiquinone] 1 subunit C2; complex I-B14.5b; human lung cancer oncogene 1 protein; NADH-ubiquinone oxidoreductase subunit B14.5b; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983", "id": "NP_001190983" } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. 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(HuGE Navigator)", "evidence": [ { "database": "RefSeq", "id": "NP_001190983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983" }, { "database": "PubMed", "id": "19064571", "url": "https://glygen.org/publication/PubMed/19064571" } ] }, { "annotation": "Observational study of gene-disease association. (HuGE Navigator) Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001190983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001190983" }, { "database": "PubMed", "id": "20877624", "url": "https://glygen.org/publication/PubMed/20877624" } ] }, { "annotation": "Polymorphic variants at NDUFC2, encoding a mitochondrial complex I subunit, associate with cardiac hypertrophy in human hypertension. 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