{ "uniprot_canonical_ac": "O75882-1", "uniprot_ac": "O75882", "uniprot_id": "ATRN_HUMAN", "mass": { "chemical_mass": 158537.0, "monoisotopic_mass": 158537.0 }, "refseq": { "ac": "NP_001193976", "name": "attractin isoform 4", "summary": "This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, "gene_names": [ { "name": "ATRN", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O75882", "id": "O75882" }, { "name": "ATRN", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976", "id": "NP_001193976" }, { "name": "DPPT-L; MGCA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976", "id": "NP_001193976" }, { "name": "KIAA0548", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O75882", "id": "O75882" }, { "name": "MGCA", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O75882", "id": "O75882" } ], "protein_names": [ { "name": "Attractin", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O75882" }, { "name": "DPPT-L", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75882" }, { "name": "Mahogany homolog", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75882" }, { "name": "attractin isoform 4", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976", "id": "NP_001193976" }, { "name": "attractin-2; mahogany protein; mahogany homolog", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976", "id": "NP_001193976" } ], "function": [ { "annotation": "ATRN encodes Attractin, which was previously shown to play a critical role in central myelination", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, { "database": "PubMed", "id": "28493104", "url": "https://glygen.org/publication/PubMed/28493104" } ] }, { "annotation": "Associated with spermatozoa", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, { "database": "PubMed", "id": "19535787", "url": "https://glygen.org/publication/PubMed/19535787" } ] }, { "annotation": "Data indicate that Attractin was involved in male reproduction in both human and BALB/c mice, but it exerted a different expression profile in different species.", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, { "database": "PubMed", "id": "25318887", "url": "https://glygen.org/publication/PubMed/25318887" } ] }, { "annotation": "Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882#function" }, { "database": "PubMed", "id": "9736737", "url": "https://glygen.org/publication/PubMed/9736737" } ] }, { "annotation": "Observational study of gene-disease association. (HuGE Navigator)", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, { "database": "PubMed", "id": "19384953", "url": "https://glygen.org/publication/PubMed/19384953" } ] }, { "annotation": "Provides the genomic basis for production of a soluble and membrane form of attractin by alternative splicing. In the process, by sequencing from positionally-determined BAC clones, confirms the localization of attractin to chromosome 20p13.", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, { "database": "PubMed", "id": "10811918", "url": "https://glygen.org/publication/PubMed/10811918" } ] }, { "annotation": "The levels of both dipeptidyl-peptidase 4 and attractin in circulating monocytes were significantly higher in obese subjects as compared with levels in lean controls or in subjects with type 2 diabetes.", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" }, { "database": "PubMed", "id": "20198559", "url": "https://glygen.org/publication/PubMed/20198559" } ] }, { "annotation": "This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016].", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs1376014557", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1376014557" }, { "id": "rs1376014557", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1376014557#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "start_pos": 1084, "end_pos": 1084, "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NLT->NLI); o-glyco-site-loss (T->I).", "chr_id": "20", "chr_pos": "3591235", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T1084", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "O75882", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O75882" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "start_pos": 733, "end_pos": 733, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "S", "sequence_mut": "R", "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NHS->NHR); o-glyco-site-loss (S->R).", "chr_id": "20", "chr_pos": "3575931", "ref_nt": "A", "alt_nt": "C", "minor_allelic_frequency": "", "site_lbl": "S733", "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": 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"id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor 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"minor_allelic_frequency": "", "site_lbl": "N1073", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs930894481", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs930894481" }, { "id": "rs930894481", "database": "ENSEMBL", "url": "https://www.ensembl.org/id/rs930894481" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "start_pos": 1073, "end_pos": 1073, "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NQS->SQS).", "chr_id": "20", "chr_pos": "3591202", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N1073", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "O75882", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O75882" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 1168, "end_pos": 1168, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "S", "sequence_mut": "N", "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-gain (SLS->NLS).", "chr_id": "20", "chr_pos": "3597939", "ref_nt": "G", "alt_nt": "A", "minor_allelic_frequency": "", "site_lbl": "S1168", "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": 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"http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "O75882", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O75882" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", 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Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "No", "trend": "down", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "O75882", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O75882" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", 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"https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O75882" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "No", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { 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"length": 1429, "header": "sp|O75882-1|ATRN_HUMAN Isoform 1 of Attractin OS=Homo sapiens OX=9606 GN=ATRN PE=1 SV=2 CANONICAL=O75882-1" }, "locus": { "chromosome": "20", "start_pos": 3646844, "end_pos": 3471108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000262919.10", "url": "https://www.ensembl.org/id/ENST00000262919.10" }, { "database": "Ensembl Peptide", "id": "ENSP00000262919.5", "url": "https://www.ensembl.org/id/ENSP00000262919.5" } ] } }, { "isoform_ac": "O75882-2", "url": "", "sequence": { "sequence": "MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPRLLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQVQTEQ", "length": 1272, "header": "sp|O75882-2|ATRN_HUMAN Isoform 2 of Attractin OS=Homo sapiens OX=9606 GN=ATRN PE=1 SV=2 CANONICAL=O75882-1" }, "locus": { "chromosome": "20", "start_pos": 3615842, "end_pos": 3471108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000446916.2", "url": "https://www.ensembl.org/id/ENST00000446916.2" }, { "database": "Ensembl Peptide", "id": "ENSP00000416587.2", "url": "https://www.ensembl.org/id/ENSP00000416587.2" } ] } }, { "isoform_ac": "O75882-3", "url": "", "sequence": { "sequence": "MVAAAAATEARLRRRTAATAALAGRSGGPHCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQVQTEQ", "length": 1198, "header": "sp|O75882-3|ATRN_HUMAN Isoform 3 of Attractin OS=Homo sapiens OX=9606 GN=ATRN PE=1 SV=2 CANONICAL=O75882-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G00912UN", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "O75882@N1043", "database": "GPTwiki", "url": "https://edwardslab.bmcb.georgetown.edu/gptwiki/O75882@N1043" } ] }, { "glytoucan_ac": "G20210JR", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G25451PN", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G40926MX", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "O75882", "database": "UniCarbKB", "url": "" }, { "id": "29671580", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "glytoucan_ac": "G47737VJ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "O75882@N1043", "database": "GPTwiki", "url": "https://edwardslab.bmcb.georgetown.edu/gptwiki/O75882@N1043" } ] }, { "glytoucan_ac": "G48414YA", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" }, { "id": "29391424", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29391424" }, { "id": "34725484", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34725484" } ] }, { "glytoucan_ac": "G49739MP", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "O75882", "database": "UniCarbKB", "url": "" }, { "id": "29671580", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "glytoucan_ac": "G59536GA", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29671580", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "glytoucan_ac": "G82830MN", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G83229XP", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G84452RH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G90093AU", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29671580", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 1043, "start_aa": "Asn", "end_pos": 1043, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1043", "evidence": [ { "id": "O75882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75882#ptm_processing" }, { "id": "16335952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/16335952" }, { "id": "23090970", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23090970" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" }, { "id": "24190977", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24190977" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 1054, "start_aa": "Asn", "end_pos": 1054, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1054", "evidence": [ { "id": "O75882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75882#ptm_processing" }, { "id": "23090970", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23090970" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" }, { "id": "24190977", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24190977" } ] }, { "glytoucan_ac": "G22310AV", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29671580", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "glytoucan_ac": "G25451PN", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G39619TI", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G48414YA", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G56784JY", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29391424", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29391424" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G83229XP", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G84452RH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "679", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/679" }, { "id": "29741879", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "glytoucan_ac": "G88374WZ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 1073, "start_aa": "Asn", "end_pos": 1073, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1073", "evidence": [ { "id": "O75882", "database": 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B., Ferreira J. A., Afonso L. P., Santos L. L., Pinto de Sousa J., Mandel U., Clausen H., Vakhrushev S. Y., Reis C. A.", "evidence": [ { "database": "UniCarbKB", "id": "O75882", "url": "" } ], "reference": [ { "type": "DOI", "id": "10.1074/mcp.M114.046862", "url": "https://glygen.org/publication/DOI/10.1074/mcp.M114.046862" } ] }, { "title": "Secreted and membrane attractin result from alternative splicing of the human ATRN gene.", "journal": "Proc. Natl. Acad. Sci. 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Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban", "date": "2014", "authors": "Cheng D, Ming Y, Li J, Chi Y, Li HG, Zou YJ, Xiong CL", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" } ], "reference": [ { "type": "PubMed", "id": "25318887", "url": "https://glygen.org/publication/PubMed/25318887" } ] }, { "title": "Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.", "journal": "Molecular & cellular proteomics : MCP", "date": "2015", "authors": "Campos D, Freitas D, Gomes J, Magalhaes A, Steentoft C, Gomes C, Vester-Christensen MB, Ferreira JA, Afonso LP, Santos LL, Pinto de Sousa J, Mandel U, Clausen H, Vakhrushev SY, Reis CA", "evidence": [ { "database": "UniCarbKB", "id": "O75882", "url": "" } ], "reference": [ { "type": "PubMed", "id": "25813380", "url": "https://glygen.org/publication/PubMed/25813380" } ] }, { "title": "A novel strategy for global mapping of O-GlcNAc proteins and peptides using selective enzymatic deglycosylation, HILIC enrichment and mass spectrometry identification.", "journal": "Talanta", "date": "2017", "authors": "Shen B, Zhang W, Shi Z, Tian F, Deng Y, Sun C, Wang G, Qin W, Qian X", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75882", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75882" } ], "reference": [ { "type": "PubMed", "id": "28411811", "url": "https://glygen.org/publication/PubMed/28411811" } ] }, { "title": "Hypomyelinating leukodystrophy associated with a deleterious mutation in the ATRN gene.", "journal": "Neurogenetics", "date": "2017", "authors": "Shahrour MA, Ashhab M, Edvardson S, Gur M, Abu-Libdeh B, Elpeleg O", "evidence": [ { "database": "RefSeq", "id": "NP_001193976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193976" } ], "reference": [ { "type": "PubMed", "id": "28493104", "url": "https://glygen.org/publication/PubMed/28493104" } ] }, { "title": "Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease.", "journal": "The Journal of pathology", "date": "2017", "authors": "Wang S, Yang F, Petyuk VA, Shukla AK, Monroe ME, Gritsenko MA, Rodland KD, Smith RD, Qian WJ, Gong CX, Liu T", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75882", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75882" } ], "reference": [ { "type": "PubMed", "id": "28657654", "url": "https://glygen.org/publication/PubMed/28657654" } ] }, { "title": "Large-scale intact glycopeptide identification by Mascot database search.", "journal": "Scientific reports", "date": "2018", "authors": "Bollineni RC, Koehler CJ, Gislefoss RE, Anonsen JH, Thiede B", "evidence": [ { "database": "GlyConnect", "id": "679", "url": "https://glyconnect.expasy.org/browser/proteins/679" } ], "reference": [ { "type": "PubMed", "id": "29391424", "url": "https://glygen.org/publication/PubMed/29391424" } ] }, { "title": "Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and alpha-1B-Glycoprotein.", "journal": "Analytical chemistry", "date": "2018", "authors": "Sun S, Hu Y, Jia L, Eshghi ST, Liu Y, Shah P, Zhang H", "evidence": [ { "database": "UniCarbKB", "id": "O75882", "url": "" }, { "database": "GlyConnect", "id": "679", "url": "https://glyconnect.expasy.org/browser/proteins/679" } ], "reference": [ { "type": "PubMed", "id": "29671580", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "title": "Reanalysis of Global Proteomic and Phosphoproteomic Data Identified a Large Number of Glycopeptides.", "journal": "Analytical chemistry", "date": "2018", "authors": "Hu Y, Shah P, Clark DJ, Ao M, Zhang H", "evidence": [ { "database": "GlyConnect", "id": "679", "url": "https://glyconnect.expasy.org/browser/proteins/679" } ], "reference": [ { "type": "PubMed", "id": "29741879", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "title": "Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes.", "journal": "Journal of proteome research", "date": "2020", "authors": "Zhu J, Lin YH, Dingess KA, Mank M, Stahl B, Heck AJR", "evidence": [ { "database": "GlyConnect", "id": "679", "url": "https://glyconnect.expasy.org/browser/proteins/679" } ], "reference": [ { "type": "PubMed", "id": "32125861", "url": "https://glygen.org/publication/PubMed/32125861" } ] }, { "title": "A Chemoenzymatic Method Based on Easily Accessible Enzymes for Profiling Protein O-GlcNAcylation.", "journal": "Analytical chemistry", "date": "2020", "authors": "Xu S, Sun F, Wu R", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75882", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75882" }, { "database": "O-GlcNAc Atlas", "id": "O75882", "url": "https://oglcnac.org/atlas/detail/O75882" } ], "reference": [ { "type": "PubMed", "id": "32574038", "url": "https://glygen.org/publication/PubMed/32574038" } ] }, { "title": "Tumor cells express pauci- and oligomannosidic N-glycans in glycoproteins recognized by the mannose receptor (CD206).", "journal": "Cellular and molecular life sciences : CMLS", "date": "2021", "authors": "Stavenhagen K, Laan LC, Gao C, Mehta AY, Heimburg-Molinaro J, Glickman JN, van Die I, Cummings RD", "evidence": [ { "database": "UniCarbKB", "id": "O75882", "url": "" } ], "reference": [ { "type": "PubMed", "id": "34089345", "url": "https://glygen.org/publication/PubMed/34089345" } ] }, { "title": "Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis.", "journal": "Nature methods", "date": "2021", "authors": "Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M", "evidence": [ { "database": "GlyConnect", "id": "679", "url": "https://glyconnect.expasy.org/browser/proteins/679" } ], "reference": [ { "type": "PubMed", "id": "34725484", "url": "https://glygen.org/publication/PubMed/34725484" } ] }, { "title": "Truncation of the TPR domain of OGT alters substrate and glycosite selection.", "journal": "Analytical and bioanalytical chemistry", "date": "2021", "authors": "Ramirez DH, Yang B, D'Souza AK, Shen D, Woo CM", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75882", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75882" } ], "reference": [ { "type": "PubMed", "id": "34725712", "url": "https://glygen.org/publication/PubMed/34725712" } ] }, { "title": "Endo-M Mediated Chemoenzymatic Approach Enables Reversible Glycopeptide Labeling for O-GlcNAcylation Analysis.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2022", "authors": "Chen Y, Tang F, Qin H, Yue X, Nie Y, Huang W, Ye M", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75882", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75882" } ], "reference": [ { "type": "PubMed", "id": "35289036", "url": "https://glygen.org/publication/PubMed/35289036" } ] }, { "title": "A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26).", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Duke-Cohan JS, Morimoto C, Rocker JA, Schlossman SF", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "reference": [ { "type": "PubMed", "id": "7539799", "url": "https://glygen.org/publication/PubMed/7539799" } ] }, { "title": "Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1998-09-15", "authors": "Duke-Cohan J S, Gu J, McLaughlin D F, Xu Y, Freeman G J, Schlossman S F", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "reference": [ { "type": "PubMed", "id": "9736737", "url": "https://glygen.org/publication/PubMed/9736737" } ] } ], "pathway": [ { "id": "hsa:8455", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:8455", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q99J86-1", "protein_name": "Attractin", "gene_name": "Atrn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAAAAAAEATEARLRGYTTATAAPAGWKERQHRPCAATGAWRPWPRAGLCLPRVLSRALSPPPLLPLLPLLFSLLLLPLPREAEAAAVAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPTGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNKIMRLRFNHFATECSWDHLYVYDGDSIYAPLIAAFSGLIVPERDGNETAPEVTVTSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKSSNSSSTVECECSENWKGESCDIPHCTDNCGFPHRGICNASDTRGCSCFPHWQGPGCSIPVPANQSFWTREEYSDLKLPRASHKAVVNGNIMWVVGGYMFNHSDYSMVLAYDLASREWLSLNHSVNSVVVRYGHSLALHKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKDQYAVVGHSAHIVTLSSGRVVMLVIFGHCPLYGYISVVQEYDLEKNTWSILQTQGALVQGGYGHSSVYDHRTKALYVHGGYKAFSANKYRLADDLYRYHVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPELHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDVLVFTSEQCDAHRSEAACVAAGPGIRCLWDTQSSRCTSWELATEEQAEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPVNHSCTEGQISIAKYDNCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLSCRNHNAFLASLTSQKKVEFVLKQLRLMQSSQSTSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSSSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSHASTGNVYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCEDLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGEECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWATSFPAGTQTGEEVPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1432 }, "evidence": [ { "id": "45918290", "url": "http://www.informatics.jax.org/homology/45918290", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VB20-1", "protein_name": "Distracted, isoform C", "gene_name": "dsd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCLAAEPPQKQPNRSSTSPTFNAKYRRKCLLLLTLLLFHGCFSGLHRAAAFNCTAHGGRCQNDGQCQEDGQCLCADGWQGPECQFCGGKVRMYHPMGTIHDGWGNYSVSVKCSWLIDARHPHWNRRHNTNPSRTANIRIHLREFATECGWDHLYIYDGDSVDSPLLAVFSGLMYRGNFSIRRVPQVIATSGTALVHFFSDDAYNMSGFNLTYKMNSCPSDSDEVECSGHGKCRDGDCICDPMYRGEACNIAACPNNCFESKNQGHCRLDQERCSCYEGFAGDDCSQISAHGAWSTVHPKHSPAPAGSASHGATIWRDTLHIVGGESYGRGKLMSTYDFNGNVWETVHPEDGSEVPDKRYGASTVMYGDKIFMYGGVVKGHGISNELWAFDVSARTWANISVRADPSCNATGGTTAMCGPLHVVGHTATLVPGYGDKNNYQYMVVIFGHSPNYGYLNTVQEFNFASREWRIVPTTGYVVKGGYGHSAAYDFLTEKVYVYGGIVSESESSQVLSSRLYAYEPATRVWSLLSAAPSARLLHTANFVNQGLMMVFGGNTHNDTSQSYGAKCYSQDLLVYDVYCDSWHYHPMPGHLQADLARFGHSSVVFEESLYIYGGFNGQLLNDMLRYQPGYCSYYTKQEKCTAARPGVKCIWDVQKMRCIAITQVQRSAIYGREQYDYVACPSKSRLTLTSELLHDVHRCQELASCQSCVSTAFGCTYCGNGVCSKERCRETTSMASVFFESSTQMAVSTASPPLNAKHLDSCPISEEYLVSSVCDQLHNCRACSANLACRWDSEHNRCKSYTSYGGLALNRTQDEVACSPSCASLTNCQNCTEDECIWCQNEQRCVDRNAYTASFPYGQCREWTTFTAKCRSAPIQSTALAVGSTTALSSAQCGYYNSCQMCLDDPACGWCDNGSNTGLGRCVVGGALAPYDDTECALKHWFFTSCPRCNCNGHSYCNDQQHCEQPCNNLTTGAHCEKCRTGYWGNPINGGKCQRCDCNGQGVYCHPDTGKCFCTTKGIVGDHCEKCDSQNHYHGDPLKGSCYYELTIDYQFTFNLSKKEDRHFTQINFRNSPGKPEIDADFTITCSVPAKMDISVKRAGSPDMLILVGVNCSTFRHRFPKTDYQFGHSPDDNSSLTTFYVFVHDFQPPIWIQIAFSQYPKLNLQQFFITFSSCFLLLLLMAAVLWKIKQKYDMFRRRQRLFVEMEQMASRPFSQVLVDIENRESIDLSLTLEGIGHLSKKRKKECPSPIALEPCSGNRAAVLSLLVRLPTGGLSQAPSGQSAGLAVASALVTLGNPRRPSIDQHPKEPKSKRKQSQHPDSCT", "length": 1323 }, "evidence": [ { "id": "O75882", "url": "https://omabrowser.org/oma/group/O75882/", "database": "OMA" } ], "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WU60-1", "protein_name": "Attractin", "gene_name": "Atrn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAVAAAAATEARLRGSTTATAAPAGRKGRQHRPCTATGAWRPGPRARLCLPRVLSRALPPPPLLPLLFSLLLLPLPREAEAAAVAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPTGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLIAAFSGLIVPERDGNETAPEVTVTSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKSSNSSSAVECECSENWKGESCDIPHCTDNCGFPHRGICNASDTRGCSCFPHWQGPGCSIPVPANQSFWTREEYSDLKLPRASHKAVVNGNIMWVVGGYMFNHSDYSMVLAYDLTSREWLPLNHSVNSVVVRYGHSLALHKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKDQYAVVGHSAHIVTLASGRVVMLVIFGHCPLYGYISVVQEYDLEKNTWSILHTQGALVQGGYGHSSVYDDRTKALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPELHHDVNRFGHSAVLYNSTMYVFGGFNSLLLSDVLVFTSEQCDAHRSEAACVAAGPGIRCLWDTQSSRCTSWELATEEQAEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPVNHSCTEGQISIAKYESCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGNGWHLVGNSCLKITTAKENYDNAKLSCRNHNAFLASLTSQKKVEFVLKQLRLMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSSSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQASAGNVYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCEDLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWATSFPAGTQTGEEVPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1428 }, "evidence": [ { "id": "45918290", "url": "http://www.informatics.jax.org/homology/45918290", "database": "MGI" }, { "id": "O75882", "url": "https://omabrowser.org/oma/group/O75882/", "database": "OMA" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "regulation of multicellular organism growth", "id": "GO:0040014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040014", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "pigmentation", "id": "GO:0043473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043473", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "cerebellum development", "id": "GO:0021549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021549", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "attractin N-glycosylated 1 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-1043 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G40926MX. Example: UniProtKB:O75882-1, Asn-1043, MOD:00160~GNO:G40926MX. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050845", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050845" } ] }, { "name": "attractin N-glycosylated 2 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-1043 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G49739MP. Example: UniProtKB:O75882-1, Asn-1043, MOD:00160~GNO:G49739MP. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050846", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050846" } ] }, { "name": "attractin N-glycosylated 3 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-1073 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:O75882-1, Asn-1073, MOD:00160~GNO:G88374WZ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050847", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050847" } ] }, { "name": "attractin N-glycosylated 4 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-1198 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O75882-1, Asn-1198, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050848", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050848" } ] }, { "name": "attractin N-glycosylated 5 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-1198 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G80475RE. Example: UniProtKB:O75882-1, Asn-1198, MOD:00160~GNO:G80475RE. [PRO:DNx, PMID:23345538]", "evidence": [ { "id": "PR:000050849", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050849" } ] }, { "name": "attractin N-glycosylated 6 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-264 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O75882-1, Asn-264, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050850", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050850" } ] }, { "name": "attractin N-glycosylated 7 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-264 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:O75882-1, Asn-264, MOD:00160~GNO:G06247RL. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050851", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050851" } ] }, { "name": "attractin N-glycosylated 8 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-325 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G28681TP. Example: UniProtKB:O75882-1, Asn-325, MOD:00160~GNO:G28681TP. [PRO:DNx, PMID:23345538]", "evidence": [ { "id": "PR:000050852", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050852" } ] }, { "name": "attractin N-glycosylated 9 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-325 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G57317CE. Example: UniProtKB:O75882-1, Asn-325, MOD:00160~GNO:G57317CE. [PRO:DNx, PMID:23345538]", "evidence": [ { "id": "PR:000050853", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050853" } ] }, { "name": "attractin N-glycosylated 10 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-623 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O75882-1, Asn-623, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050854", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050854" } ] }, { "name": "attractin N-glycosylated 11 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-731 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O75882-1, Asn-731, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050855", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050855" } ] }, { "name": "attractin N-glycosylated 12 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-731 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:O75882-1, Asn-731, MOD:00160~GNO:G06247RL. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050856", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050856" } ] }, { "name": "attractin N-glycosylated 13 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-731 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:O75882-1, Asn-731, MOD:00160~GNO:G08293MJ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050857", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050857" } ] }, { "name": "attractin N-glycosylated 14 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-731 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:O75882-1, Asn-731, MOD:00160~GNO:G59626AS. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050858", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050858" } ] }, { "name": "attractin N-glycosylated 15 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-731 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:O75882-1, Asn-731, MOD:00160~GNO:G88374WZ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050859", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050859" } ] }, { "name": "attractin N-glycosylated 16 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-863 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:O75882-1, Asn-863, MOD:00160~GNO:G10486CT. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050860", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050860" } ] }, { "name": "attractin N-glycosylated 17 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-863 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G50073PQ. Example: UniProtKB:O75882-1, Asn-863, MOD:00160~GNO:G50073PQ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050861", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050861" } ] }, { "name": "attractin N-glycosylated 18 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-863 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G83555HU. Example: UniProtKB:O75882-1, Asn-863, MOD:00160~GNO:G83555HU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050862", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050862" } ] }, { "name": "attractin N-glycosylated 19 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-914 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O75882-1, Asn-914, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050863", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050863" } ] }, { "name": "attractin N-glycosylated 20 (human)", "definition": "An attractin (human) that has been N-glycosylated at the residue equivalent to Asn-914 of the amino acid sequence represented by UniProtKB:O75882-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:O75882-1, Asn-914, MOD:00160~GNO:G59626AS. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000050864", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050864" } ] } ], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1054, "end_pos": 1056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1082, "end_pos": 1084, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1198, "end_pos": 1200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1206, "end_pos": 1208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1250, "end_pos": 1252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1259, "end_pos": 1261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 923, "end_pos": 925, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Heavily glycosylated.", "evidence": [ { "database": "UniProtKB", "id": "O75882", "url": "https://www.uniprot.org/uniprot/O75882" }, { "database": "PubMed", "id": "19159218", "url": "https://glygen.org/publication/PubMed/19159218" }, { "database": "PubMed", "id": "14760718", "url": "https://glygen.org/publication/PubMed/14760718" }, { "database": "PubMed", "id": "16335952", "url": "https://glygen.org/publication/PubMed/16335952" }, { "database": "PubMed", "id": "7539799", "url": "https://glygen.org/publication/PubMed/7539799" }, { "database": "PubMed", "id": "17261078", "url": "https://glygen.org/publication/PubMed/17261078" }, { "database": "PubMed", "id": "19139490", "url": "https://glygen.org/publication/PubMed/19139490" } ] } ], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 213, 237, 242, 253, 264, 300, 325, 362, 383, 416, 428, 575, 623, 731, 863, 914, 923, 986, 1043, 1054, 1073, 1082, 1198, 1206, 1250, 1259 ], "o_linked_sites": [ 146, 733, 735, 1084, 1085 ], "snv_sites": [ 173, 213, 244, 261, 286, 292, 300, 302, 338, 351, 353, 362, 364, 383, 385, 428, 575, 576, 625, 718, 731, 733, 748, 820, 865, 871, 914, 916, 925, 986, 1073, 1084, 1168, 1204, 1250, 1259, 1261, 1334 ], "glycation_sites": [], "phosphorylation_sites": [ 1185 ], "sequon_annotation_sites": [ { "start_pos": 1043, "end_pos": 1045 }, { "start_pos": 1054, "end_pos": 1056 }, { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 1082, "end_pos": 1084 }, { "start_pos": 1198, "end_pos": 1200 }, { "start_pos": 1206, "end_pos": 1208 }, { "start_pos": 1250, "end_pos": 1252 }, { "start_pos": 1259, "end_pos": 1261 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 731, "end_pos": 733 }, { "start_pos": 863, "end_pos": 865 }, { "start_pos": 914, "end_pos": 916 }, { "start_pos": 923, "end_pos": 925 }, { "start_pos": 986, "end_pos": 988 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 145 }, { "field": "total_sites", "count": 31 }, { "field": "n_linked_glycans", "count": 70 }, { "field": "n_linked_glycan_sites", "count": 41 }, { "field": "o_linked_glycans", "count": 2 }, { "field": "o_linked_glycan_sites", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 19 }, { "field": "total_sites", "count": 19 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 19 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 119 }, { "field": "total_sites", "count": 20 }, { "field": "n_linked_glycans", "count": 70 }, { "field": "n_linked_glycan_sites", "count": 15 }, { "field": "o_linked_glycans", "count": 2 }, { "field": "o_linked_glycan_sites", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 7 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 45 }, { "field": "total_sites", "count": 38 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 10 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 35 }, { "field": "total_sites", "count": 29 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }