{ "uniprot_canonical_ac": "O75385-1", "uniprot_ac": "O75385", "uniprot_id": "ULK1_HUMAN", "mass": { "chemical_mass": 112631.0, "monoisotopic_mass": 112631.0 }, "refseq": { "ac": "NP_003556", "name": "serine/threonine-protein kinase ULK1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556" }, "gene_names": [ { "name": "ULK1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O75385", "id": "O75385" }, { "name": "ATG1; ATG1A; hATG1; UNC51; Unc51.1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556", "id": "NP_003556" }, { "name": "KIAA0722", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O75385", "id": "O75385" }, { "name": "ULK1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556", "id": "NP_003556" } ], "protein_names": [ { "name": "Serine/threonine-protein kinase ULK1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O75385" }, { "name": "2.7.11.1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75385" }, { "name": "ATG1 autophagy related 1 homolog; autophagy-related protein 1 homolog", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556", "id": "NP_003556" }, { "name": "ATG1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75385" }, { "name": "Autophagy-related protein 1 homolog", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75385" }, { "name": "Unc-51-like kinase 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75385" }, { "name": "hATG1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O75385" }, { "name": "serine/threonine-protein kinase ULK1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556", "id": "NP_003556" } ], "function": [ { "annotation": "An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.", "evidence": [ { "database": "RefSeq", "id": "NP_003556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556" }, { "database": "PubMed", "id": "37846507", "url": "https://glygen.org/publication/PubMed/37846507" } ] }, { "annotation": "Serine/threonine-protein kinase involved in autophagy in response to starvation (PubMed:18936157, PubMed:21460634, PubMed:21795849, PubMed:23524951, PubMed:25040165, PubMed:31123703, PubMed:29487085). Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes (PubMed:18936157, PubMed:21460634, PubMed:21795849, PubMed:25040165). Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR (PubMed:21795849). Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity (PubMed:21460634). May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences (PubMed:18936157). Plays a role early in neuronal differentiation and is required for granule cell axon formation (PubMed:11146101). May also phosphorylate SESN2 and SQSTM1 to regulate autophagy (PubMed:25040165). Phosphorylates FLCN, promoting autophagy (PubMed:25126726). Phosphorylates AMBRA1 in response to autophagy induction, releasing AMBRA1 from the cytoskeletal docking site to induce autophagosome nucleation (PubMed:20921139). Phosphorylates ATG4B, leading to inhibit autophagy by decreasing both proteolytic activation and delipidation activities of ATG4B (PubMed:28821708).", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385#function" }, { "database": "PubMed", "id": "21795849", "url": "https://glygen.org/publication/PubMed/21795849" }, { "database": "PubMed", "id": "25040165", "url": "https://glygen.org/publication/PubMed/25040165" }, { "database": "PubMed", "id": "21460634", "url": "https://glygen.org/publication/PubMed/21460634" }, { "database": "PubMed", "id": "29487085", "url": "https://glygen.org/publication/PubMed/29487085" }, { "database": "PubMed", "id": "18936157", "url": "https://glygen.org/publication/PubMed/18936157" }, { "database": "PubMed", "id": "31123703", "url": "https://glygen.org/publication/PubMed/31123703" }, { "database": "PubMed", "id": "23524951", "url": "https://glygen.org/publication/PubMed/23524951" }, { "database": "PubMed", "id": "11146101", "url": "https://glygen.org/publication/PubMed/11146101" }, { "database": "PubMed", "id": "25126726", "url": "https://glygen.org/publication/PubMed/25126726" }, { "database": "PubMed", "id": "20921139", "url": "https://glygen.org/publication/PubMed/20921139" }, { "database": "PubMed", "id": "28821708", "url": "https://glygen.org/publication/PubMed/28821708" } ] }, { "annotation": "Starvation-induced autophagy, which requires mAtg9, may rely on an alteration of the steady-state trafficking of mAtg9, in a Atg1-dependent manner.", "evidence": [ { "database": "RefSeq", "id": "NP_003556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556" }, { "database": "PubMed", "id": "16940348", "url": "https://glygen.org/publication/PubMed/16940348" } ] }, { "annotation": "Transferrin promotes chondrogenic differentiation in condylar growth through inducing autophagy via ULK1-ATG16L1 axis.", "evidence": [ { "database": "RefSeq", "id": "NP_003556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556" }, { "database": "PubMed", "id": "37694282", "url": "https://glygen.org/publication/PubMed/37694282" } ] }, { "annotation": "ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation.", "evidence": [ { "database": "RefSeq", "id": "NP_003556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556" }, { "database": "PubMed", "id": "37774021", "url": "https://glygen.org/publication/PubMed/37774021" } ] }, { "annotation": "ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.", "evidence": [ { "database": "RefSeq", "id": "NP_003556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_003556" }, { "database": "PubMed", "id": "37267363", "url": "https://glygen.org/publication/PubMed/37267363" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs1368711867", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1368711867" }, { "id": "rs1368711867", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1368711867#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 409, "end_pos": 409, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SSS->NSS); o-glyco-site-loss (S->N).", "chr_id": "12", "chr_pos": "131913815", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S409", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "O75385", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O75385" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 279, "end_pos": 279, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "D", "sequence_mut": "N", "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-gain (DAS->NAS).", "chr_id": "12", "chr_pos": "131910280", "ref_nt": "G", "alt_nt": "A", "minor_allelic_frequency": "", "site_lbl": "D279", "disease": [ { "disease_id": "DOID:363", "recommended_name": { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine cancer", "description": "A female reproductive organ cancer that is located_in the uterus." }, "synonyms": [ { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "CA - cancer of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "Tumour of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterus neoplasm", "description": "" } ] } ], "keywords": [ "biomuta", "somatic", "cancer", "disease" ] }, { "evidence": [ { "id": "O75385", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O75385" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 305, "end_pos": 305, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "S", "sequence_mut": "N", "comment": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-gain (SSS->NSS).", "chr_id": "12", "chr_pos": "131910766", "ref_nt": "G", "alt_nt": "A", "minor_allelic_frequency": "", "site_lbl": "S305", "disease": [ { "disease_id": "DOID:363", "recommended_name": { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine cancer", "description": "A female reproductive organ cancer that is located_in the uterus." }, "synonyms": [ { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "CA - cancer of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "Tumour of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterus neoplasm", "description": "" } ] } ], "keywords": [ "biomuta", "somatic", "cancer", "disease" ] }, { "evidence": [ { "id": "rs1442377592", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1442377592" }, { "id": "rs1442377592", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1442377592#frequency_tab" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 409, "end_pos": 409, "sequence_org": "S", "sequence_mut": "G", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->G).", "chr_id": "12", "chr_pos": "131913814", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S409", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1380638645", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1380638645" }, { "id": "rs1380638645", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1380638645" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 518, "end_pos": 518, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SGT->NGT).", "chr_id": "12", "chr_pos": "131915365", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S518", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs752111469", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs752111469" }, { "id": "rs752111469", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs752111469" }, { "id": "rs752111469", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs752111469" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 54, "end_pos": 54, "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NLA->NLT).", "chr_id": "12", "chr_pos": "131895649", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A54", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs141683636", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs141683636" }, { "id": "rs141683636", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs141683636" }, { "id": "rs141683636", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs141683636#frequency_tab" }, { "id": "rs141683636", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs141683636" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 663, "end_pos": 663, "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (DLS->NLS).", "chr_id": "12", "chr_pos": "131916506", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D663", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs761255869", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs761255869" }, { "id": "rs761255869", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs761255869" }, { "id": "rs761255869", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs761255869" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 746, "end_pos": 746, "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (TSS->NSS).", "chr_id": "12", "chr_pos": "131917465", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T746", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1376185022", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1376185022" }, { "id": "rs1376185022", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1376185022#frequency_tab" }, { "id": "rs1376185022", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1376185022" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 755, "end_pos": 755, "sequence_org": "T", "sequence_mut": "A", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (T->A).", "chr_id": "12", "chr_pos": "131917491", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T755", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "O75385", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O75385" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 755, "end_pos": 755, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "T", "sequence_mut": "I", "comment": "Somatic mutation passed 1 out of 6 filters: o-glyco-site-loss (T->I).", "chr_id": "12", "chr_pos": "131917492", "ref_nt": "C", "alt_nt": "T", "minor_allelic_frequency": "", "site_lbl": "T755", "disease": [ { "disease_id": "DOID:1115", "recommended_name": { "id": "DOID:1115", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1115", "name": "sarcoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm." }, "synonyms": [ { "id": "DOID:1115", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1115", "name": "connective and soft tissue neoplasm", "description": "" }, { "id": "DOID:1115", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1115", "name": "tumor of soft tissue and skeleton", "description": "" } ] } ], "keywords": [ "biomuta", "somatic", "cancer", "disease" ] }, { "evidence": [ { "id": "rs1279130564", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1279130564" }, { "id": "rs1279130564", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1279130564" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 761, "end_pos": 761, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SGS->NGS).", "chr_id": "12", "chr_pos": "131917510", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S761", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1331233257", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1331233257" }, { "id": "rs1331233257", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1331233257" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 866, "end_pos": 866, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SAS->NAS).", "chr_id": "12", "chr_pos": "131919297", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S866", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs759654957", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs759654957" }, { "id": "rs759654957", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs759654957" }, { "id": "rs759654957", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs759654957" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 973, "end_pos": 973, "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SIT->NIT).", "chr_id": "12", "chr_pos": "131920093", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S973", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [ { "start_pos": 46, "end_pos": 46, "sequence_org": "K", "sequence_mut": "I", "comment": "Abolished serine/threonine-protein kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "PubMed", "id": "20921139", "url": "https://glygen.org/publication/PubMed/20921139" }, { "database": "PubMed", "id": "28821708", "url": "https://glygen.org/publication/PubMed/28821708" } ] } ], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "77.84", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000177169" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "70.6", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000177169" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "76.04", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000177169" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "79.27", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000177169" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "92.25", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000177169" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "74.71", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000177169" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "68.55", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000177169", "url": 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"MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the 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"description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "No", "trend": "up", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "O75385", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O75385" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", 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"https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O75385" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { "database": "BioXpress", "id": "O75385", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O75385" } ], "disease": [ { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", 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"MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA", 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"length": 1050, "header": "sp|O75385-1|ULK1_HUMAN Isoform 1 of Serine/threonine-protein kinase ULK1 OS=Homo sapiens OX=9606 GN=ULK1 PE=1 SV=2 CANONICAL=O75385-1" }, "locus": { "chromosome": "12", "start_pos": 131921358, "end_pos": 131895002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000321867.6", "url": "https://www.ensembl.org/id/ENST00000321867.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000324560.3", "url": "https://www.ensembl.org/id/ENSP00000324560.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 409, "start_aa": "Ser", "end_pos": 409, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser409", "evidence": [ { "id": "O75385", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75385" }, { "id": "30517873", 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"29321306", "url": "https://glygen.org/publication/PubMed/29321306" }, { "database": "PubMed", "id": "30024813", "url": "https://glygen.org/publication/PubMed/30024813" }, { "database": "PubMed", "id": "32693121", "url": "https://glygen.org/publication/PubMed/32693121" }, { "database": "PubMed", "id": "33898322", "url": "https://glygen.org/publication/PubMed/33898322" }, { "database": "PubMed", "id": "34604061", "url": "" }, { "database": "PubMed", "id": "25891078", "url": "https://glygen.org/publication/PubMed/25891078" } ], "site_lbl": "Ser317" }, { "start_pos": 403, "end_pos": 403, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" }, { "database": "iPTMnet", "id": "O75385", "url": 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"kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" }, { "database": "PubMed", "id": "33654220", "url": "https://glygen.org/publication/PubMed/33654220" } ], "site_lbl": "Ser411" }, { "start_pos": 415, "end_pos": 415, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" }, { "database": "PubMed", "id": "33654220", "url": "https://glygen.org/publication/PubMed/33654220" } ], "site_lbl": "Ser415" }, { "start_pos": 423, "end_pos": 423, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" }, { "database": 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"phospho.ELM", "id": "O75385", "url": "http://phospho.elm.eu.org/byAccession/O75385.html" } ], "site_lbl": "Thr456" }, { "start_pos": 459, "end_pos": 459, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser459" }, { "start_pos": 460, "end_pos": 460, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser460" }, { "start_pos": 465, "end_pos": 465, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", 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protrusions along microtubules: role of Rab7 and RILP.", "journal": "Molecular and cellular biology", "date": "2003", "authors": "Harrison RE, Bucci C, Vieira OV, Schroer TA, Grinstein S", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "12944476", "url": "https://glygen.org/publication/PubMed/12944476" } ] }, { "title": "RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway.", "journal": "Journal of cell science", "date": "2003", "authors": "Kajiho H, Saito K, Tsujita K, Kontani K, Araki Y, Kurosu H, Katada T", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "12972505", "url": "https://glygen.org/publication/PubMed/12972505" } ] }, { "title": "IG20, in contrast to DENN-SV, (MADD splice variants) 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"Rab13 regulates PKA signaling during tight junction assembly.", "journal": "The Journal of cell biology", "date": "2004", "authors": "Kohler K, Louvard D, Zahraoui A", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15096524", "url": "https://glygen.org/publication/PubMed/15096524" } ] }, { "title": "Rab7 is required for the normal progression of the autophagic pathway in mammalian cells.", "journal": "Journal of cell science", "date": "2004", "authors": "Gutierrez MG, Munafo DB, Beron W, Colombo MI", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15138286", "url": "https://glygen.org/publication/PubMed/15138286" } ] }, { "title": "The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway.", "journal": "Cell", "date": "1992", "authors": "Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, Hoflack B, Zerial M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "1516130", "url": "https://glygen.org/publication/PubMed/1516130" } ] }, { "title": "HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Tanida I, Sou YS, Ezaki J, Minematsu-Ikeguchi N, Ueno T, Kominami E", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "15187094", "url": "https://glygen.org/publication/PubMed/15187094" } ] }, { "title": "Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Kunita R, Otomo A, Mizumura H, Suzuki K, Showguchi-Miyata J, Yanagisawa Y, Hadano S, Ikeda JE", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15247254", "url": "https://glygen.org/publication/PubMed/15247254" } ] }, { "title": "De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.", "journal": "Nature", "date": "2004", "authors": "Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "15258597", "url": "https://glygen.org/publication/PubMed/15258597" } ] }, { "title": "ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics.", "journal": "FEBS letters", "date": "2004", "authors": "Hadano S, Otomo A, Suzuki-Utsunomiya K, Kunita R, Yanagisawa Y, Showguchi-Miyata J, Mizumura H, Ikeda JE", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15388334", "url": "https://glygen.org/publication/PubMed/15388334" } ] }, { "title": "Rab13 mediates the continuous endocytic recycling of occludin to the cell surface.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Morimoto S, Nishimura N, Terai T, Manabe S, Yamamoto Y, Shinahara W, Miyake H, Tashiro S, Shimada M, Sasaki T", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15528189", "url": "https://glygen.org/publication/PubMed/15528189" } ] }, { "title": "A role for the small GTPase Rab21 in the early endocytic pathway.", "journal": "Journal of cell science", "date": "2004", "authors": "Simpson JC, Griffiths G, Wessling-Resnick M, Fransen JA, Bennett H, Jones AT", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15561770", "url": "https://glygen.org/publication/PubMed/15561770" } ] }, { "title": "ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling.", "journal": "The EMBO journal", "date": "2005", "authors": "Reiss K, Maretzky T, Ludwig A, Tousseyn T, de Strooper B, Hartmann D, Saftig P", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "15692570", "url": "https://glygen.org/publication/PubMed/15692570" } ] }, { "title": "Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Reiley W, Zhang M, Wu X, Granger E, Sun SC", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "15870263", "url": "https://glygen.org/publication/PubMed/15870263" } ] }, { "title": "Characterization of the human GARP (Golgi associated retrograde protein) complex.", "journal": "Experimental cell research", "date": "2005", "authors": "Liewen H, Meinhold-Heerlein I, Oliveira V, Schwarzenbacher R, Luo G, Wadle A, Jung M, Pfreundschuh M, 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"https://glygen.org/publication/PubMed/16373702" } ] }, { "title": "A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint.", "journal": "The EMBO journal", "date": "2006", "authors": "Miserey-Lenkei S, Couedel-Courteille A, Del Nery E, Bardin S, Piel M, Racine V, Sibarita JB, Perez F, Bornens M, Goud B", "evidence": [ { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "16395330", "url": "https://glygen.org/publication/PubMed/16395330" } ] }, { "title": "Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Hunker CM, Galvis A, Kruk I, Giambini H, Veisaga ML, Barbieri MA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": 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"https://glygen.org/publication/PubMed/16525121" } ] }, { "title": "Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans.", "journal": "Molecular biology of the cell", "date": "2006", "authors": "Mahoney TR, Liu Q, Itoh T, Luo S, Hadwiger G, Vincent R, Wang ZW, Fukuda M, Nonet ML", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "16571673", "url": "https://glygen.org/publication/PubMed/16571673" } ] }, { "title": "Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.", "journal": "Molecular biology of the cell", "date": "2006", "authors": "Babbey CM, Ahktar N, Wang E, Chen CC, Grant BD, Dunn KW", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "16641372", "url": "https://glygen.org/publication/PubMed/16641372" } ] }, { "title": "MADD/DENN splice variant of the IG20 gene is necessary and sufficient for cancer cell survival.", "journal": "Oncogene", "date": "2006", "authors": "Mulherkar N, Ramaswamy M, Mordi DC, Prabhakar BS", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "16682944", "url": "https://glygen.org/publication/PubMed/16682944" } ] }, { "title": "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.", "journal": "The Journal of cell biology", "date": "2006", "authors": "Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "16754960", "url": "https://glygen.org/publication/PubMed/16754960" } ] }, { "title": "A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.", "journal": "Nature cell biology", "date": "2006", "authors": "Fluhrer R, Grammer G, Israel L, Condron MM, Haffner C, Friedmann E, Bohland C, Imhof A, Martoglio B, Teplow DB, Haass C", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "16829951", "url": "https://glygen.org/publication/PubMed/16829951" } ] }, { "title": "SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production.", "journal": "Nature cell biology", "date": "2006", "authors": "Friedmann E, Hauben E, Maylandt K, Schleeger S, Vreugde S, Lichtenthaler SF, Kuhn PH, Stauffer D, Rovelli G, Martoglio B", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": 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"https://glygen.org/publication/PubMed/17043139" } ] }, { "title": "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.", "journal": "Cell", "date": "2006", "authors": "Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "17081983", "url": "https://glygen.org/publication/PubMed/17081983" } ] }, { "title": "Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2007", "authors": "Schuck S, Gerl MJ, Ang A, Manninen A, Keller P, Mellman I, Simons K", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17132146", "url": "https://glygen.org/publication/PubMed/17132146" 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"https://glygen.org/publication/PubMed/17192257" } ] }, { "title": "Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells.", "journal": "Biochemical and biophysical research communications", "date": "2007", "authors": "Ishikura S, Bilan PJ, Klip A", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17208202", "url": "https://glygen.org/publication/PubMed/17208202" } ] }, { "title": "ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.", "journal": "Biochemical and biophysical research communications", "date": "2007", "authors": "Suzuki-Utsunomiya K, Hadano S, Otomo A, Kunita R, Mizumura H, Osuga H, Ikeda JE", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17239822", "url": "https://glygen.org/publication/PubMed/17239822" } ] }, { "title": "TRAPPI tethers COPII vesicles by binding the coat subunit Sec23.", "journal": "Nature", "date": "2007", "authors": "Cai H, Yu S, Menon S, Cai Y, Lazarova D, Fu C, Reinisch K, Hay JC, Ferro-Novick S", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17287728", "url": "https://glygen.org/publication/PubMed/17287728" } ] }, { "title": "MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Mulherkar N, Prasad KV, Prabhakar BS", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "17314102", "url": "https://glygen.org/publication/PubMed/17314102" } ] }, { "title": "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007", "authors": "Sugiyama N, Masuda T, Shinoda K, Nakamura A, Tomita M, Ishihama Y", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "17322306", "url": "https://glygen.org/publication/PubMed/17322306" } ] }, { "title": "Patterns of somatic mutation in human cancer genomes.", "journal": "Nature", "date": "2007", "authors": "Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "17344846", "url": "https://glygen.org/publication/PubMed/17344846" } ] }, { "title": "Rab18 inhibits secretory activity in neuroendocrine cells by interacting with secretory granules.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2007", "authors": "Vazquez-Martinez R, Cruz-Garcia D, Duran-Prado M, Peinado JR, Castano JP, Malagon MM", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17488286", "url": "https://glygen.org/publication/PubMed/17488286" } ] }, { "title": "Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways.", "journal": "The Journal of cell biology", "date": "2007", "authors": "Fuchs E, Haas AK, Spooner RA, Yoshimura S, Lord JM, Barr FA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", 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"17658474", "url": "https://glygen.org/publication/PubMed/17658474" } ] }, { "title": "Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis.", "journal": "Molecular biology of the cell", "date": "2007", "authors": "Lopes VS, Wasmeier C, Seabra MC, Futter CE", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17671165", "url": "https://glygen.org/publication/PubMed/17671165" } ] }, { "title": "Rab22B's role in trans-Golgi network membrane dynamics.", "journal": "Biochemical and biophysical research communications", "date": "2007", "authors": "Ng EL, Wang Y, Tang BL", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "17678623", "url": "https://glygen.org/publication/PubMed/17678623" } ] }, { "title": "Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP.", "journal": "Current biology : CB", "date": "2007", "authors": "Zhu G, Wu CJ, Zhao Y, Ashwell JD", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "17702576", "url": "https://glygen.org/publication/PubMed/17702576" } ] }, { "title": "TBC1D20 is a Rab1 GTPase-activating protein that mediates hepatitis C virus replication.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Sklan EH, Serrano RL, Einav S, Pfeffer SR, Lambright DG, Glenn JS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "17901050", "url": "https://glygen.org/publication/PubMed/17901050" } ] }, { "title": "Rab10 in insulin-stimulated GLUT4 translocation.", "journal": "The Biochemical journal", "date": "2008", "authors": "Sano H, Roach WG, Peck GR, Fukuda M, Lienhard GE", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18076383", "url": "https://glygen.org/publication/PubMed/18076383" } ] }, { "title": "The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.", "journal": "Molecular biology of the cell", "date": "2008", "authors": "Yamamura R, Nishimura N, Nakatsuji H, Arase S, Sasaki T", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18094055", "url": "https://glygen.org/publication/PubMed/18094055" } ] }, { 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"https://glygen.org/publication/PubMed/18466115" } ] }, { "title": "Varp interacts with Rab38 and functions as its potential effector.", "journal": "Biochemical and biophysical research communications", "date": "2008", "authors": "Wang F, Zhang H, Zhang X, Wang Y, Ren F, Zhang X, Zhai Y, Chang Z", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18477474", "url": "https://glygen.org/publication/PubMed/18477474" } ] }, { "title": "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Figueiredo AC, Wasmeier C, Tarafder AK, Ramalho JS, Baron RA, Seabra MC", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18559336", "url": "https://glygen.org/publication/PubMed/18559336" } ] }, { "title": "The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes.", "journal": "Cell", "date": "2008", "authors": "Cai Y, Chin HF, Lazarova D, Menon S, Fu C, Cai H, Sclafani A, Rodgers DW, De La Cruz EM, Ferro-Novick S, Reinisch KM", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18585354", "url": "https://glygen.org/publication/PubMed/18585354" } ] }, { "title": "Rab18 and Rab43 have key roles in ER-Golgi trafficking.", "journal": "Journal of cell science", "date": "2008", "authors": "Dejgaard SY, Murshid A, Erman A, Kizilay O, Verbich D, Lodge R, Dejgaard K, Ly-Hartig TB, Pepperkok R, Simpson JC, Presley JF", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18664496", "url": "https://glygen.org/publication/PubMed/18664496" } ] }, { "title": "A quantitative atlas of mitotic phosphorylation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "18669648", "url": "https://glygen.org/publication/PubMed/18669648" } ] }, { "title": "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.", "journal": "Molecular cell", "date": "2008", "authors": "Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "18691976", "url": "https://glygen.org/publication/PubMed/18691976" } ] }, { "title": "Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation.", "journal": "American journal of physiology. Cell physiology", "date": "2008", "authors": "Ishikura S, Klip A", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18701652", "url": "https://glygen.org/publication/PubMed/18701652" } ] }, { "title": "Successive and selective release of phosphorylated peptides captured by hydroxy acid-modified metal oxide chromatography.", "journal": "Journal of proteome research", "date": "2008", "authors": "Kyono Y, Sugiyama N, Imami K, Tomita M, Ishihama Y", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "18767875", "url": "https://glygen.org/publication/PubMed/18767875" } ] }, { "title": "Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells.", "journal": "The Journal of cell biology", "date": "2008", "authors": "Nokes RL, Fields IC, Collins RN, Folsch H", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18779367", "url": "https://glygen.org/publication/PubMed/18779367" } ] }, { "title": "Integrin trafficking regulated by Rab21 is necessary for cytokinesis.", "journal": "Developmental cell", "date": "2008", "authors": "Pellinen T, Tuomi S, Arjonen A, Wolf M, Edgren H, Meyer H, Grosse R, Kitzing T, Rantala JK, Kallioniemi O, Fassler R, Kallio M, Ivaska J", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "18804435", "url": "https://glygen.org/publication/PubMed/18804435" } ] }, { "title": "Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.", "journal": "Molecular and cellular biology", "date": "2009", "authors": "Chan EY, Longatti A, McKnight NC, Tooze SA", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "18936157", "url": "https://glygen.org/publication/PubMed/18936157" } ] }, { "title": "rab5 controls early endosome fusion in vitro.", "journal": "Cell", "date": "1991", "authors": "Gorvel JP, Chavrier P, Zerial M, Gruenberg J", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "1900457", "url": "https://glygen.org/publication/PubMed/1900457" } ] }, { "title": "Tracing the retrograde route in protein trafficking.", "journal": "Cell", "date": "2008", "authors": "Johannes L, Popoff V", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19109890", "url": "https://glygen.org/publication/PubMed/19109890" } ] }, { "title": "Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.", "journal": "Mol. Biol. Cell", "date": "2009", "authors": "Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "19211835", "url": "https://glygen.org/publication/PubMed/19211835" } ] }, { "title": "Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation.", "journal": "Structure (London, England : 1993)", "date": "2009", "authors": "Keller N, Mares J, Zerbe O, Grutter MG", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "19278658", "url": "https://glygen.org/publication/PubMed/19278658" } ] }, { "title": "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.", "journal": "Autophagy", "date": "2009", "authors": "Mercer CA, Kaliappan A, Dennis PB", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "19287211", "url": "https://glygen.org/publication/PubMed/19287211" } ] }, { "title": "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Kurada BR, Li LC, Mulherkar N, Subramanian M, Prasad KV, Prabhakar BS", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "19289468", "url": "https://glygen.org/publication/PubMed/19289468" } ] }, { "title": "The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.", "journal": "The EMBO journal", "date": "2009", "authors": "Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "19322194", "url": "https://glygen.org/publication/PubMed/19322194" } ] }, { "title": "Transport of mannose-6-phosphate receptors from the trans-Golgi network to endosomes requires Rab31.", "journal": "Experimental cell research", "date": "2009", "authors": "Rodriguez-Gabin AG, Yin X, Si Q, Larocca JN", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19345684", "url": "https://glygen.org/publication/PubMed/19345684" } ] }, { "title": "Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes.", "journal": "Molecular biology of the cell", "date": "2009", "authors": "Tamura K, Ohbayashi N, Maruta Y, Kanno E, Itoh T, Fukuda M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19403694", "url": "https://glygen.org/publication/PubMed/19403694" } ] }, { "title": "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.", "journal": "Analytical chemistry", "date": "2009", "authors": "Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "19413330", "url": "https://glygen.org/publication/PubMed/19413330" } ] }, { "title": "Mechanism of procaspase-8 activation by c-FLIPL.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Yu JW, Jeffrey PD, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "19416807", "url": "https://glygen.org/publication/PubMed/19416807" } ] }, { "title": "RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport.", "journal": "Cell", "date": "2009", "authors": "Espinosa EJ, Calero M, Sridevi K, Pfeffer SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19490898", "url": "https://glygen.org/publication/PubMed/19490898" } ] }, { "title": "AMPK in Health and Disease.", "journal": "Physiological reviews", "date": "2009", "authors": "Steinberg GR, Kemp BE", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "19584320", "url": "https://glygen.org/publication/PubMed/19584320" } ] }, { "title": "Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy.", "journal": "The EMBO journal", "date": "2009", "authors": "Vergne I, Roberts E, Elmaoued RA, Tosch V, Delgado MA, Proikas-Cezanne T, Laporte J, Deretic V", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "19590496", "url": "https://glygen.org/publication/PubMed/19590496" } ] }, { "title": "Atg101, a novel mammalian autophagy protein interacting with Atg13.", "journal": "Autophagy", "date": "2009", "authors": "Hosokawa N, Sasaki T, Iemura S, Natsume T, Hara T, Mizushima N", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "19597335", "url": "https://glygen.org/publication/PubMed/19597335" } ] }, { "title": "Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network.", "journal": "Molecular and cellular biology", "date": "2009", "authors": "Perez-Victoria FJ, Bonifacino JS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19620288", "url": "https://glygen.org/publication/PubMed/19620288" } ] }, { "title": "Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Pan C, Olsen JV, Daub H, Mann M", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "19651622", "url": "https://glygen.org/publication/PubMed/19651622" } ] }, { "title": "mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles.", "journal": "Molecular biology of the cell", "date": "2009", "authors": "Yamasaki A, Menon S, Yu S, Barrowman J, Meerloo T, Oorschot V, Klumperman J, Satoh A, Ferro-Novick S", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19656848", "url": "https://glygen.org/publication/PubMed/19656848" } ] }, { "title": "Phosphoproteomic analysis of human embryonic stem cells.", "journal": "Cell stem cell", "date": "2009", "authors": "Brill LM, Xiong W, Lee KB, Ficarro SB, Crain A, Xu Y, Terskikh A, Snyder EY, Ding S", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "19664994", "url": "https://glygen.org/publication/PubMed/19664994" } ] }, { "title": "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.", "journal": "Science signaling", "date": "2009", "authors": "Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "19690332", "url": "https://glygen.org/publication/PubMed/19690332" } ] }, { "title": "Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.", "journal": "Journal of cellular physiology", "date": "2009", "authors": "Ng EL, Ng JJ, Liang F, Tang BL", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19725050", "url": "https://glygen.org/publication/PubMed/19725050" } ] }, { "title": "Rab35 controls actin bundling by recruiting fascin as an effector protein.", "journal": "Science (New York, N.Y.)", "date": "2009", "authors": "Zhang J, Fonovic M, Suyama K, Bogyo M, Scott MP", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19729655", "url": "https://glygen.org/publication/PubMed/19729655" } ] }, { "title": "Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth.", "journal": "EMBO reports", "date": "2009", "authors": "Burgo A, Sotirakis E, Simmler MC, Verraes A, Chamot C, Simpson JC, Lanzetti L, Proux-Gillardeaux V, Galli T", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "19745841", "url": "https://glygen.org/publication/PubMed/19745841" } ] }, { "title": "3D tomography reveals connections between the phagophore and endoplasmic reticulum.", "journal": "Autophagy", "date": "2009", "authors": "Yla-Anttila P, Vihinen H, Jokitalo E, Eskelinen EL", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "19855179", "url": "https://glygen.org/publication/PubMed/19855179" } ] }, { "title": "A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation.", "journal": "Nature cell biology", "date": "2009", "authors": "Hayashi-Nishino M, Fujita N, Noda T, Yamaguchi A, Yoshimori T, Yamamoto A", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "19898463", "url": "https://glygen.org/publication/PubMed/19898463" } ] }, { "title": "Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Xu G, Tan X, Wang H, Sun W, Shi Y, Burlingame S, Gu X, Cao G, Zhang T, Qin J, Yang J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "19910467", "url": "https://glygen.org/publication/PubMed/19910467" } ] }, { "title": "Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Sakane A, Honda K, Sasaki T", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "20008558", "url": "https://glygen.org/publication/PubMed/20008558" } ] }, { "title": "Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2010", "authors": "Taguchi-Atarashi N, Hamasaki M, Matsunaga K, Omori H, Ktistakis NT, Yoshimori T, Noda T", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "20059746", "url": "https://glygen.org/publication/PubMed/20059746" } ] }, { "title": "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.", "journal": "Science signaling", "date": "2010", "authors": "Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ] }, { "title": "Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.", "journal": "Genes, chromosomes & cancer", "date": "2010", "authors": "Sato N, Koinuma J, Ito T, Tsuchiya E, Kondo S, Nakamura Y, Daigo Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "20095038", "url": "https://glygen.org/publication/PubMed/20095038" } ] }, { "title": "Armus is a Rac1 effector that inactivates Rab7 and regulates E-cadherin degradation.", "journal": "Current biology : CB", "date": "2010", "authors": "Frasa MA, Maximiano FC, Smolarczyk K, Francis RE, Betson ME, Lozano E, Goldenring J, Seabra MC, Rak A, Ahmadian MR, Braga VM", "evidence": [ { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "20116244", "url": "https://glygen.org/publication/PubMed/20116244" } ] }, { "title": "The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Marat AL, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "20154091", "url": "https://glygen.org/publication/PubMed/20154091" } ] }, { "title": "Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephaly.", "journal": "American journal of human genetics", "date": "2010", "authors": "Giannandrea M, Bianchi V, Mignogna ML, Sirri A, Carrabino S, D'Elia E, Vecellio M, Russo S, Cogliati F, Larizza L, Ropers HH, Tzschach A, Kalscheuer V, Oehl-Jaschkowitz B, Skinner C, Schwartz CE, Gecz J, Van Esch H, Raynaud M, Chelly J, de Brouwer AP, Toniolo D, D'Adamo P", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "20159109", "url": "https://glygen.org/publication/PubMed/20159109" } ] }, { "title": "The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes.", "journal": "Molecular cell", "date": "2010", "authors": "Allaire PD, Marat AL, Dall'Armi C, Di Paolo G, McPherson PS, Ritter B", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": 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"url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "20219915", "url": "https://glygen.org/publication/PubMed/20219915" } ] }, { "title": "TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Parvatiyar K, Barber GN, Harhaj EW", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "20304918", "url": "https://glygen.org/publication/PubMed/20304918" } ] }, { "title": "Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.", "journal": "Nature", "date": "2010", "authors": "Kinchen JM, Ravichandran KS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": 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dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.", "journal": "The Journal of cell biology", "date": "2010", "authors": "Di Bartolomeo S, Corazzari M, Nazio F, Oliverio S, Lisi G, Antonioli M, Pagliarini V, Matteoni S, Fuoco C, Giunta L, D'Amelio M, Nardacci R, Romagnoli A, Piacentini M, Cecconi F, Fimia GM", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "20921139", "url": "https://glygen.org/publication/PubMed/20921139" } ] }, { "title": "Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.", "journal": "The Journal of cell biology", "date": "2010", "authors": "Yoshimura S, Gerondopoulos A, Linford A, Rigden DJ, Barr FA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": 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cleavage and alters substrate specificity.", "journal": "The Biochemical journal", "date": "2011", "authors": "Pop C, Oberst A, Drag M, Van Raam BJ, Riedl SJ, Green DR, Salvesen GS", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "21235526", "url": "https://glygen.org/publication/PubMed/21235526" } ] }, { "title": "AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.", "journal": "Nature cell biology", "date": "2011", "authors": "Kim J, Kundu M, Viollet B, Guan KL", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "21258367", "url": "https://glygen.org/publication/PubMed/21258367" } ] }, { "title": "Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "21273506", "url": "https://glygen.org/publication/PubMed/21273506" } ] }, { "title": "DENN domain proteins: regulators of Rab GTPases.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Marat AL, Dokainish H, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ 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inhibition of TNF\u03b1-induced NF-\u03baB activation.", "journal": "PloS one", "date": "2011-03-07", "authors": "Nagabhushana Ananthamurthy, Bansal Megha, Swarup Ghanshyam", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "21408173", "url": "https://glygen.org/publication/PubMed/21408173" } ] }, { "title": "Entry at the trans-face of the Golgi.", "journal": "Cold Spring Harbor perspectives in biology", "date": "2011", "authors": "Pfeffer SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "21421921", "url": "https://glygen.org/publication/PubMed/21421921" } ] }, { "title": "A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis.", "journal": "PLoS biology", "date": "2011", "authors": "Taylor MJ, 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"database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "21586568", "url": "https://glygen.org/publication/PubMed/21586568" } ] }, { "title": "Membrane dynamics and fusion at late endosomes and vacuoles--Rab regulation, multisubunit tethering complexes and SNAREs.", "journal": "European journal of cell biology", "date": "2011", "authors": "Epp N, Rethmeier R, Kramer L, Ungermann C", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "21683469", "url": "https://glygen.org/publication/PubMed/21683469" } ] }, { "title": "Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis.", "journal": "Nature cell biology", "date": "2011", "authors": "Dambournet D, Machicoane M, Chesneau L, Sachse M, Rocancourt M, El Marjou A, Formstecher E, Salomon R, Goud B, Echard A", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "21706022", "url": "https://glygen.org/publication/PubMed/21706022" } ] }, { "title": "Small GTPase Rab12 regulates constitutive degradation of transferrin receptor.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2011", "authors": "Matsui T, Itoh T, Fukuda M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "21718402", "url": "https://glygen.org/publication/PubMed/21718402" } ] }, { "title": "Distinct yet overlapping roles of Rab GTPases on synaptic vesicles.", "journal": "Small GTPases", "date": "2011", "authors": "Pavlos NJ, Jahn R", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } 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"https://glygen.org/publication/PubMed/22072793" } ] }, { "title": "The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.", "journal": "Autophagy", "date": "2012", "authors": "Tanida I, Yamasaki M, Komatsu M, Ueno T", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "22170151", "url": "https://glygen.org/publication/PubMed/22170151" } ] }, { "title": "The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes.", "journal": "Molecular biology of the cell", "date": "2012", "authors": "Ohbayashi N, Yatsu A, Tamura K, Fukuda M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "22171327", "url": "https://glygen.org/publication/PubMed/22171327" } ] }, { "title": "De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF.", "journal": "Cell death and differentiation", "date": "2012", "authors": "Mahul-Mellier AL, Pazarentzos E, Datler C, Iwasawa R, AbuAli G, Lin B, Grimm S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "22179575", "url": "https://glygen.org/publication/PubMed/22179575" } ] }, { "title": "EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.", "journal": "Molecular biology of the cell", "date": "2012", "authors": "Hokanson DE, Bretscher AP", "evidence": [ { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "22219378", "url": "https://glygen.org/publication/PubMed/22219378" } ] 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between Golgi organization and membrane trafficking?", "journal": "Cellular and molecular life sciences : CMLS", "date": "2012", "authors": "Liu S, Storrie B", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "22581368", "url": "https://glygen.org/publication/PubMed/22581368" } ] }, { "title": "Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.", "journal": "Developmental cell", "date": "2012", "authors": "Linford A, Yoshimura S, Nunes Bastos R, Langemeyer L, Gerondopoulos A, Rigden DJ, Barr FA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "22595670", "url": "https://glygen.org/publication/PubMed/22595670" } ] }, { "title": "TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.", "journal": "J. Cell Biol.", "date": "2012", "authors": "Longatti A, Lamb CA, Razi M, Yoshimura S, Barr FA, Tooze SA", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "22613832", "url": "https://glygen.org/publication/PubMed/22613832" } ] }, { "title": "Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.", "journal": "Nature", "date": "2012", "authors": "Zeigerer A, Gilleron J, Bogorad RL, Marsico G, Nonaka H, Seifert S, Epstein-Barash H, Kuchimanchi S, Peng CG, Ruda VM, Del Conte-Zerial P, Hengstler JG, Kalaidzidis Y, Koteliansky V, Zerial M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "22622570", "url": 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"https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "22983554", "url": "https://glygen.org/publication/PubMed/22983554" } ] }, { "title": "TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Goueli BS, Powell MB, Finger EC, Pfeffer SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854214" } ], "reference": [ { "type": "PubMed", "id": "23019362", "url": "https://glygen.org/publication/PubMed/23019362" } ] }, { "title": "BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor.", "journal": "Current biology : CB", "date": "2012", "authors": "Gerondopoulos A, Langemeyer L, Liang JR, Linford A, Barr FA", "evidence": [ { "database": "Reactome", "id": 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"id": "23176493", "url": "https://glygen.org/publication/PubMed/23176493" } ] }, { "title": "Toward a comprehensive characterization of a human cancer cell phosphoproteome.", "journal": "Journal of proteome research", "date": "2013", "authors": "Zhou H, Di Palma S, Preisinger C, Peng M, Polat AN, Heck AJ, Mohammed S", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" } ] }, { "title": "Maturation of autophagosomes and endosomes: a key role for Rab7.", "journal": "Biochimica et biophysica acta", "date": "2013", "authors": "Hyttinen JM, Niittykoski M, Salminen A, Kaarniranta K", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "23220125", "url": "https://glygen.org/publication/PubMed/23220125" } ] }, { "title": "Molecular insights into vesicle tethering at the Golgi by the conserved oligomeric Golgi (COG) complex and the golgin TATA element modulatory factor (TMF).", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Miller VJ, Sharma P, Kudlyk TA, Frost L, Rofe AP, Watson IJ, Duden R, Lowe M, Lupashin VV, Ungar D", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "23239882", "url": "https://glygen.org/publication/PubMed/23239882" } ] }, { "title": "Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.", "journal": "Small GTPases", "date": "2013", "authors": "Bultema JJ, Di Pietro SM", "evidence": [ { "database": "Reactome", 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induces both apoptosis and autophagy in cultured head and neck squamous cell carcinoma cells.", "journal": "PloS one", "date": "2013", "authors": "Yang YL, Ji C, Bi ZG, Lu CC, Wang R, Gu B, Cheng L", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "23372762", "url": "https://glygen.org/publication/PubMed/23372762" } ] }, { "title": "The highly conserved COPII coat complex sorts cargo from the endoplasmic reticulum and targets it to the golgi.", "journal": "Cold Spring Harbor perspectives in biology", "date": "2013", "authors": "Lord C, Ferro-Novick S, Miller EA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "23378591", "url": "https://glygen.org/publication/PubMed/23378591" } ] }, { "title": "Mutation spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and genotype-phenotype correlations in warburg micro syndrome and Martsolf syndrome.", "journal": "Human mutation", "date": "2013", "authors": "Handley MT, Morris-Rosendahl DJ, Brown S, Macdonald F, Hardy C, Bem D, Carpanini SM, Borck G, Martorell L, Izzi C, Faravelli F, Accorsi P, Pinelli L, Basel-Vanagaite L, Peretz G, Abdel-Salam GM, Zaki MS, Jansen A, Mowat D, Glass I, Stewart H, Mancini G, Lederer D, Roscioli T, Giuliano F, Plomp AS, Rolfs A, Graham JM, Seemanova E, Poo P, Garcia-Cazorla A, Edery P, Jackson IJ, Maher ER, Aligianis IA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "23420520", "url": "https://glygen.org/publication/PubMed/23420520" } ] }, { "title": "A role for Rab14 in the endocytic trafficking of GLUT4 in 3T3-L1 adipocytes.", "journal": "Journal of cell science", "date": "2013", "authors": "Reed SE, Hodgson LR, Song S, May MT, Kelly 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activation by interfering with the interaction between TRAF2 and the IKK complex.", "journal": "Cell research", "date": "2014", "authors": "Yao F, Long LY, Deng YZ, Feng YY, Ying GY, Bao WD, Li G, Guan DX, Zhu YQ, Li JJ, Xie D", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "24323043", "url": "https://glygen.org/publication/PubMed/24323043" } ] }, { "title": "Engagement of the small GTPase Rab31 protein and its effector, early endosome antigen 1, is important for trafficking of the ligand-bound epidermal growth factor receptor from the early to the late endosome.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Chua CE, Tang BL", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "24644286", "url": 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Tooze SA", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "24954904", "url": "https://glygen.org/publication/PubMed/24954904" } ] }, { "title": "Bioinformatics analysis reveals disturbance mechanism of MAPK signaling pathway and cell cycle in Glioblastoma multiforme.", "journal": "Gene", "date": "2014", "authors": "Li W, Li K, Zhao L, Zou H", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "24967941", "url": "https://glygen.org/publication/PubMed/24967941" } ] }, { "title": "Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1.", "journal": "The FEBS journal", "date": "2014", "authors": "Ro SH, Semple IA, Park H, Park H, Park HW, Kim M, Kim JS, Lee JH", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "25040165", "url": "https://glygen.org/publication/PubMed/25040165" } ] }, { "title": "Post-transcriptional regulation of autophagy in C2C12 myotubes following starvation and nutrient restoration.", "journal": "The international journal of biochemistry & cell biology", "date": "2014", "authors": "Desgeorges MM, Freyssenet D, Chanon S, Castells J, Pugniere P, Bechet D, Peinnequin A, Devillard X, Defour A", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "25043686", "url": "https://glygen.org/publication/PubMed/25043686" } ] }, { "title": "Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.", "journal": "Science signaling", "date": "2014", "authors": "Nishikimi A, Ishihara S, Ozawa M, Etoh K, Fukuda M, Kinashi T, Katagiri K", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25074980", "url": "https://glygen.org/publication/PubMed/25074980" } ] }, { "title": "FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.", "journal": "Autophagy", "date": "2014", "authors": "Dunlop EA, Seifan S, Claessens T, Behrends C, Kamps MA, Rozycka E, Kemp AJ, Nookala RK, Blenis J, Coull BJ, Murray JT, van Steensel MA, Wilkinson S, Tee AR", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "25126726", "url": "https://glygen.org/publication/PubMed/25126726" } ] }, { "title": "TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.", "journal": "Dev. Cell", "date": "2014", "authors": "Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Munch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "25127057", "url": "https://glygen.org/publication/PubMed/25127057" } ] }, { "title": "Rab proteins and the compartmentalization of the endosomal system.", "journal": "Cold Spring Harbor perspectives in biology", "date": "2014", "authors": "Wandinger-Ness A, Zerial M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25341920", "url": "https://glygen.org/publication/PubMed/25341920" } ] }, { "title": "Membrane tethering.", "journal": "F1000prime reports", "date": "2014", "authors": "Chia PZ, Gleeson PA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25343031", "url": "https://glygen.org/publication/PubMed/25343031" } ] }, { "title": "AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.", "journal": "Nat. Cell Biol.", "date": "2015", "authors": "Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, Gretzmeier C, Dengjel J, Fimia GM, Piacentini M, Di Bartolomeo S, Velasco G, Cecconi F", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "25438055", "url": "https://glygen.org/publication/PubMed/25438055" } ] }, { "title": "The role of the small GTPase Rab31 in cancer.", "journal": "Journal of cellular and molecular medicine", "date": "2015", "authors": "Chua CE, Tang BL", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25472813", "url": "https://glygen.org/publication/PubMed/25472813" } ] }, { "title": "The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling.", "journal": "Oncotarget", "date": "2014", "authors": "Rajan N, Elliott RJ, Smith A, Sinclair N, Swift S, Lord CJ, Ashworth A", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "25565632", "url": "https://glygen.org/publication/PubMed/25565632" } ] }, { "title": "Membrane dynamics in autophagosome biogenesis.", "journal": "Journal of cell science", "date": "2015", "authors": "Carlsson SR, Simonsen A", "evidence": [ { "database": "Reactome", "id": "R-HSA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632852" } ], "reference": [ { "type": "PubMed", "id": "25568151", "url": "https://glygen.org/publication/PubMed/25568151" } ] }, { "title": "Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion.", "journal": "EMBO reports", "date": "2015", "authors": "Jean S, Cox S, Nassari S, Kiger AA", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25648148", "url": "https://glygen.org/publication/PubMed/25648148" } ] }, { "title": "DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.", "journal": "The Journal of cell biology", "date": "2015", "authors": "Ioannou MS, Bell ES, Girard M, Chaineau M, Hamlin JN, Daubaras M, Monast A, Park M, Hodgson L, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25713415", "url": "https://glygen.org/publication/PubMed/25713415" } ] }, { "title": "IRGM governs the core autophagy machinery to conduct antimicrobial defense.", "journal": "Molecular cell", "date": "2015", "authors": "Chauhan S, Mandell MA, Deretic V", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "25891078", "url": "https://glygen.org/publication/PubMed/25891078" } ] }, { "title": "Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy.", "journal": "EMBO reports", "date": "2015", "authors": "Xu J, Fotouhi M, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "25925668", "url": "https://glygen.org/publication/PubMed/25925668" } ] }, { "title": "Activation of autophagy in human skeletal muscle is dependent on exercise intensity and AMPK activation.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2015", "authors": "Schwalm C, Jamart C, Benoit N, Naslain D, Premont C, Prevet J, Van Thienen R, Deldicque L, Francaux M", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "25957282", "url": "https://glygen.org/publication/PubMed/25957282" } ] }, { "title": "Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors.", "journal": "The Journal of biological chemistry", "date": "2015", "authors": "Kulasekaran G, Nossova N, Marat AL, Lund I, Cremer C, Ioannou MS, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26055712", "url": "https://glygen.org/publication/PubMed/26055712" } ] }, { "title": "DENND3: a signaling/trafficking interface in autophagy.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2015", "authors": "Xu J, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26177209", "url": "https://glygen.org/publication/PubMed/26177209" } ] }, { "title": "The Critical Role of Rab31 in Cell Proliferation and Apoptosis in Cancer Progression.", "journal": "Molecular neurobiology", "date": "2016", "authors": "Pan Y, Zhang Y, Chen L, Liu Y, Feng Y, Yan J", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26245486", "url": "https://glygen.org/publication/PubMed/26245486" } ] }, { "title": "NF-kappaB-Independent Role of IKKalpha/IKKbeta in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling.", "journal": "Molecular cell", "date": "2015", "authors": "Dondelinger Y, Jouan-Lanhouet S, Divert T, Theatre E, Bertin J, Gough PJ, Giansanti P, Heck AJ, Dejardin E, Vandenabeele P, Bertrand MJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "26344099", "url": "https://glygen.org/publication/PubMed/26344099" } ] }, { "title": "TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.", "journal": "J. Cell Biol.", "date": "2015", "authors": "Kimura T, Jain A, Choi SW, Mandell MA, Schroder K, Johansen T, Deretic V", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "26347139", "url": "https://glygen.org/publication/PubMed/26347139" } ] }, { "title": "PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer.", "journal": "Oncogene", "date": "2016", "authors": "Fan SJ, Snell C, Turley H, Li JL, McCormick R, Perera SM, Heublein S, Kazi S, Azad A, Wilson C, Harris AL, Goberdhan DC", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26434594", "url": "https://glygen.org/publication/PubMed/26434594" } ] }, { "title": "A complex of Rab13 with MICAL-L2 and alpha-actinin-4 is essential for insulin-dependent GLUT4 exocytosis.", "journal": "Molecular biology of the cell", "date": "2016", "authors": "Sun Y, Jaldin-Fincati J, Liu Z, Bilan PJ, Klip A", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26538022", "url": "https://glygen.org/publication/PubMed/26538022" } ] }, { "title": "Triptolide induces protective autophagy through activation of the CaMKKbeta-AMPK signaling pathway in prostate cancer cells.", "journal": "Oncotarget", "date": "2016", "authors": "Zhao F, Huang W, Zhang Z, Mao L, Han Y, Yan J, Lei M", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "26734992", "url": "https://glygen.org/publication/PubMed/26734992" } ] }, { "title": "CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.", "journal": "Nature cell biology", "date": "2016", "authors": "Seo J, Lee EW, Sung H, Seong D, Dondelinger Y, Shin J, Jeong M, Lee HK, Kim JH, Han SY, Lee C, Seong JK, Vandenabeele P, Song J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "26900751", "url": "https://glygen.org/publication/PubMed/26900751" } ] }, { "title": "Small RAB GTPases Regulate Multiple Steps of Mitosis.", "journal": "Frontiers in cell and developmental biology", "date": "2016", "authors": "Miserey-Lenkei S, Colombo MI", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26925400", "url": "https://glygen.org/publication/PubMed/26925400" } ] }, { "title": "Rab14 limits the sorting of Glut4 from endosomes into insulin-sensitive regulated secretory compartments in adipocytes.", "journal": "The Biochemical journal", "date": "2016", "authors": "Brewer PD, Habtemichael EN, Romenskaia I, Coster AC, Mastick CC", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "26936971", "url": "https://glygen.org/publication/PubMed/26936971" } ] }, { "title": "CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.", "journal": "Cell reports", "date": "2016", "authors": "Hrdinka M, Fiil BK, Zucca M, Leske D, Bagola K, Yabal M, Elliott PR, Damgaard RB, Komander D, Jost PJ, Gyrd-Hansen M", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "26997266", "url": "https://glygen.org/publication/PubMed/26997266" } ] }, { "title": "Rab1 in cell signaling, cancer and other diseases.", "journal": "Oncogene", "date": "2016", "authors": "Yang XZ, Li XX, Zhang YJ, Rodriguez-Rodriguez L, Xiang MQ, Wang HY, Zheng XF", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "27041585", "url": "https://glygen.org/publication/PubMed/27041585" } ] }, { "title": "Regulation of Cancer Cell Behavior by the Small GTPase Rab13.", "journal": "The Journal of biological chemistry", "date": "2016", "authors": "Ioannou MS, McPherson PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "27044746", "url": "https://glygen.org/publication/PubMed/27044746" } ] }, { "title": "Multiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARP.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2016", "authors": "Fukuda M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "27103185", "url": "https://glygen.org/publication/PubMed/27103185" } ] }, { "title": "Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases.", "journal": "Cell structure and function", "date": "2016", "authors": "Ishida M, E Oguchi M, Fukuda M", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "27246931", "url": "https://glygen.org/publication/PubMed/27246931" } ] }, { "title": "SPATA2 links CYLD to the TNF-alpha receptor signaling complex and modulates the receptor signaling outcomes.", "journal": "The EMBO journal", "date": "2016", "authors": "Wagner SA, Satpathy S, Beli P, Choudhary C", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "27307491", "url": "https://glygen.org/publication/PubMed/27307491" } ] }, { "title": "Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2016", "authors": "Klinkert K, Echard A", "evidence": [ { "database": "Reactome", "id": "R-HSA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876198" } ], "reference": [ { "type": "PubMed", "id": "27329675", "url": "https://glygen.org/publication/PubMed/27329675" } ] }, { "title": "The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.", "journal": "EMBO J.", "date": "2016", "authors": "Webster Christopher P, Smith Emma F, Bauer Claudia S, Moller Annekathrin, Hautbergue Guillaume M, Ferraiuolo Laura, Myszczynska Monika A, Higginbottom Adrian, Walsh Matthew J, Whitworth Alexander J, Kaspar Brian K, Meyer Kathrin, Shaw Pamela J, Grierson Andrew J, De Vos Kurt J", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "27334615", "url": "https://glygen.org/publication/PubMed/27334615" } ] }, { "title": "SPATA2 promotes CYLD activity and regulates TNF-induced NF-kappaB signaling and cell death.", "journal": "EMBO reports", "date": "2016", "authors": "Schlicher L, Wissler M, Preiss F, Brauns-Schubert P, Jakob C, Dumit V, Borner C, Dengjel J, Maurer U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "27458237", "url": "https://glygen.org/publication/PubMed/27458237" } ] }, { "title": "SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.", "journal": "Cell reports", "date": "2016", "authors": "Kupka S, De Miguel D, Draber P, Martino L, Surinova S, Rittinger K, Walczak H", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "27545878", "url": "https://glygen.org/publication/PubMed/27545878" } ] }, { "title": "Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.", "journal": "Nature communications", "date": "2016-08-24", "authors": "Nakazawa Seshiru, Oikawa Daisuke, Ishii Ryohei, Ayaki Takashi, Takahashi Hirotaka, Takeda Hiroyuki, Ishitani Ryuichiro, Kamei Kiyoko, Takeyoshi Izumi, Kawakami Hideshi, Iwai Kazuhiro, Hatada Izuho, Sawasaki Tatsuya, Ito Hidefumi, Nureki Osamu, Tokunaga Fuminori", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "27552911", "url": "https://glygen.org/publication/PubMed/27552911" } ] }, { "title": "SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.", "journal": "Molecular cell", "date": "2016", "authors": "Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "27591049", "url": "https://glygen.org/publication/PubMed/27591049" } ] }, { "title": "mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1.", "journal": "Scientific reports", "date": "2016", "authors": "Manzoni C, Mamais A, Roosen DA, Dihanich S, Soutar MP, Plun-Favreau H, Bandopadhyay R, Hardy J, Tooze SA, Cookson MR, Lewis PA", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "27731364", "url": "https://glygen.org/publication/PubMed/27731364" } ] }, { "title": "A systems study reveals concurrent activation of AMPK and mTOR by amino acids.", "journal": "Nature communications", "date": "2016", "authors": "Dalle Pezze P, Ruf S, Sonntag AG, Langelaar-Makkinje M, Hall P, Heberle AM, Razquin Navas P, van Eunen K, Tolle RC, Schwarz JJ, Wiese H, Warscheid B, Deitersen J, Stork B, Fassler E, Schauble S, Hahn U, Horvatovich P, Shanley DP, Thedieck K", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "27869123", "url": "https://glygen.org/publication/PubMed/27869123" } ] }, { "title": "PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide.", "journal": "Oncotarget", "date": "2017", "authors": "Booth L, Roberts JL, Poklepovic A, Gordon S, Dent P", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "27903966", "url": "https://glygen.org/publication/PubMed/27903966" } ] }, { "title": "Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.", "journal": "Cell death and differentiation", "date": "2017", "authors": "Hwang JY, Gertner M, Pontarelli F, Court-Vazquez B, Bennett MV, Ofengeim D, Zukin RS", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "27935582", "url": "https://glygen.org/publication/PubMed/27935582" } ] }, { "title": "The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo.", "journal": "Oncotarget", "date": "2017", "authors": "Booth L, Roberts JL, Sander C, Lee J, Kirkwood JM, Poklepovic A, Dent P", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "28146421", "url": "https://glygen.org/publication/PubMed/28146421" } ] }, { "title": "Autophagy inhibits cell death induced by the anti-cancer drug morusin.", "journal": "American journal of cancer research", "date": "2017", "authors": "Cho SW, Na W, Choi M, Kang SJ, Lee SG, Choi CY", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "28401008", "url": "https://glygen.org/publication/PubMed/28401008" } ] }, { "title": "MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.", "journal": "Molecular cell", "date": "2017", "authors": "Jaco I, Annibaldi A, Lalaoui N, Wilson R, Tenev T, Laurien L, Kim C, Jamal K, Wicky John S, Liccardi G, Chau D, Murphy JM, Brumatti G, Feltham R, Pasparakis M, Silke J, Meier P", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "28506461", "url": "https://glygen.org/publication/PubMed/28506461" } ] }, { "title": "WIPI3 and WIPI4 beta-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bakula D, Muller AJ, Zuleger T, Takacs Z, Franz-Wachtel M, Thost AK, Brigger D, Tschan MP, Frickey T, Robenek H, Macek B, Proikas-Cezanne T", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "28561066", "url": "https://glygen.org/publication/PubMed/28561066" } ] }, { "title": "RIG-I and IL-6 are negative-feedback regulators of STING induced by double-stranded DNA.", "journal": "PloS one", "date": "2017", "authors": "Wu X, Yang J, Na T, Zhang K, Davidoff AM, Yuan BZ, Wang Y", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "28806404", "url": "https://glygen.org/publication/PubMed/28806404" } ] }, { "title": "A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B.", "journal": "Nature communications", "date": "2017", "authors": "Pengo N, Agrotis A, Prak K, Jones J, Ketteler R", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "28821708", "url": "https://glygen.org/publication/PubMed/28821708" } ] }, { "title": "Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation.", "journal": "Nature communications", "date": "2017", "authors": "Sanchez-Wandelmer J, Kriegenburg F, Rohringer S, Schuschnig M, Gomez-Sanchez R, Zens B, Abreu S, Hardenberg R, Hollenstein D, Gao J, Ungermann C, Martens S, Kraft C, Reggiori F", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "28821724", "url": "https://glygen.org/publication/PubMed/28821724" } ] }, { "title": "The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.", "journal": "Mol. Cell", "date": "2017", "authors": "Zhao YG, Chen Y, Miao G, Zhao H, Qu W, Li D, Wang Z, Liu N, Li L, Chen S, Liu P, Feng D, Zhang H", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "28890335", "url": "https://glygen.org/publication/PubMed/28890335" } ] }, { "title": "Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation.", "journal": "Genes & development", "date": "2017", "authors": "Ruan HB, Ma Y, Torres S, Zhang B, Feriod C, Heck RM, Qian K, Fu M, Li X, Nathanson MH, Bennett AM, Nie Y, Ehrlich BE, Yang X", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75385", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75385" } ], "reference": [ { "type": "PubMed", "id": "28903979", "url": "https://glygen.org/publication/PubMed/28903979" } ] }, { "title": "MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.", "journal": "Nature cell biology", "date": "2017", "authors": "Dondelinger Y, Delanghe T, Rojas-Rivera D, Priem D, Delvaeye T, Bruggeman I, Van Herreweghe F, Vandenabeele P, Bertrand MJM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "28920952", "url": "https://glygen.org/publication/PubMed/28920952" } ] }, { "title": "p38(MAPK)/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection.", "journal": "Nature cell biology", "date": "2017", "authors": "Menon MB, Gropengiesser J, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M, Ruckdeschel K", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "28920954", "url": "https://glygen.org/publication/PubMed/28920954" } ] }, { "title": "AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells.", "journal": "Oncotarget", "date": "2017-09-15", "authors": "Song Yarong, Zhang Peng, Sun Yadong, Li Xuechao, Chen Lifeng, Xiao Yajun, Xing Yifei", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "28978086", "url": "https://glygen.org/publication/PubMed/28978086" } ] }, { "title": "Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling.", "journal": "Oncotarget", "date": "2017-10-17", "authors": "Han Bing, Yu Yi-Qun, Yang Qi-Lian, Shen Chun-Ying, Wang Xiao-Juan", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "29156790", "url": "https://glygen.org/publication/PubMed/29156790" } ] }, { "title": "Increased autophagy signaling but not proteasome activity in human skeletal muscle after prolonged low-intensity exercise with negative energy balance.", "journal": "Physiological reports", "date": "2017", "authors": "Moberg M, Hendo G, Jakobsson M, Mattsson CM, Ekblom-Bak E, Flockhart M, Ponten M, Soderlund K, Ekblom B", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "29208687", "url": "https://glygen.org/publication/PubMed/29208687" } ] }, { "title": "Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway.", "journal": "BMC pulmonary medicine", "date": "2017", "authors": "Gui D, Cui Z, Zhang L, Yu C, Yao D, Xu M, Chen M, Wu P, Li G, Wang L, Huang X", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "29233105", "url": "https://glygen.org/publication/PubMed/29233105" } ] }, { "title": "Digitoxin Suppresses Human Cytomegalovirus Replication via Na(+), K(+)/ATPase alpha1 Subunit-Dependent AMP-Activated Protein Kinase and Autophagy Activation.", "journal": "Journal of virology", "date": "2018", "authors": "Mukhopadhyay R, Venkatadri R, Katsnelson J, Arav-Boger R", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "29321306", "url": "https://glygen.org/publication/PubMed/29321306" } ] }, { "title": "The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.", "journal": "EMBO reports", "date": "2018", "authors": "Kim JH, Seo D, Kim SJ, Choi DW, Park JS, Ha J, Choi J, Lee JH, Jung SM, Seo KW, Lee EW, Lee YS, Cheong H, Choi CY, Park SH", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "29487085", "url": "https://glygen.org/publication/PubMed/29487085" } ] }, { "title": "mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.", "journal": "Bioscience reports", "date": "2018", "authors": "Manzoni C, Mamais A, Dihanich S, Soutar MPM, Plun-Favreau H, Bandopadhyay R, Abeti R, Giunti P, Hardy J, R Cookson M, Tooze SA, Lewis PA", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "29563162", "url": "https://glygen.org/publication/PubMed/29563162" } ] }, { "title": "Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.", "journal": "Cell reports", "date": "2018", "authors": "Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, Thompson AJ, Nesvizhskii A, Schmidt A, Komander D, Wu H, Martin S, Meier P", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "29642005", "url": "https://glygen.org/publication/PubMed/29642005" } ] }, { "title": "The CHK1 inhibitor SRA737 synergizes with PARP1 inhibitors to kill carcinoma cells.", "journal": "Cancer biology & therapy", "date": "2018", "authors": "Booth L, Roberts J, Poklepovic A, Dent P", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "30024813", "url": "https://glygen.org/publication/PubMed/30024813" } ] }, { "title": "NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation.", "journal": "Oncogenesis", "date": "2018", "authors": "Shin JH, Park CW, Yoon G, Hong SM, Choi KY", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "30093610", "url": "https://glygen.org/publication/PubMed/30093610" } ] }, { "title": "TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.", "journal": "Cell", "date": "2018", "authors": "Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "30146158", "url": "https://glygen.org/publication/PubMed/30146158" } ] }, { "title": "Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy.", "journal": "Nature communications", "date": "2018", "authors": "Wang C, Wang H, Zhang D, Luo W, Liu R, Xu D, Diao L, Liao L, Liu Z", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "30154410", "url": "https://glygen.org/publication/PubMed/30154410" } ] }, { "title": "Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFalpha-induced apoptosis.", "journal": "The Journal of biological chemistry", "date": "2018", "authors": "Tang Y, Joo D, Liu G, Tu H, You J, Jin J, Zhao X, Hung MC, Lin X", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "30361438", "url": "https://glygen.org/publication/PubMed/30361438" } ] }, 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"30420664", "url": "https://glygen.org/publication/PubMed/30420664" } ] }, { "title": "ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation.", "journal": "Cell reports", "date": "2018", "authors": "Pyo KE, Kim CR, Lee M, Kim JS, Kim KI, Baek SH", "evidence": [ { "database": "O-GlcNAc Database", "id": "O75385", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75385" }, { "database": "O-GlcNAc Atlas", "id": "O75385", "url": "https://oglcnac.org/atlas/detail/O75385" } ], "reference": [ { "type": "PubMed", "id": "30517873", "url": "https://glygen.org/publication/PubMed/30517873" } ] }, { "title": "Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation.", "journal": "Nature communications", "date": "2019", "authors": "Dondelinger Y, Delanghe T, Priem D, Wynosky-Dolfi MA, Sorobetea D, Rojas-Rivera D, Giansanti P, Roelandt R, Gropengiesser J, Ruckdeschel K, Savvides SN, Heck AJR, Vandenabeele P, Brodsky IE, Bertrand MJM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "30988283", "url": "https://glygen.org/publication/PubMed/30988283" } ] }, { "title": "Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains.", "journal": "Science advances", "date": "2019", "authors": "Di Rienzo M, Antonioli M, Fusco C, Liu Y, Mari M, Orhon I, Refolo G, Germani F, Corazzari M, Romagnoli A, Ciccosanti F, Mandriani B, Pellico MT, De La Torre R, Ding H, Dentice M, Neri M, Ferlini A, Reggiori F, Kulesz-Martin M, Piacentini M, Merla G, Fimia GM", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "reference": [ { "type": "PubMed", "id": "31123703", "url": "https://glygen.org/publication/PubMed/31123703" } ] }, { "title": "The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD.", "journal": "The Journal of biological chemistry", "date": "2019", "authors": "Uematsu A, Kido K, Takahashi H, Takahashi C, Yanagihara Y, Saeki N, Yoshida S, Maekawa M, Honda M, Kai T, Shimizu K, Higashiyama S, Imai Y, Tokunaga F, Sawasaki T", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "31366726", "url": "https://glygen.org/publication/PubMed/31366726" } ] }, { "title": "TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ.", "journal": "Cell death & disease", "date": "2019", "authors": "Lu H, Xiao J, Ke C, Ni X, Xiu R, Tian Q, Pan H, Zou L, Wang F, Ma T, Ji X, Yuan P, Liu L, Zhang J, Jia W, Duan Q, Zhu F", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "31378785", "url": "https://glygen.org/publication/PubMed/31378785" } ] }, { "title": "Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.", "journal": "Nature", "date": "2019", "authors": "Newton K, Wickliffe KE, Dugger DL, Maltzman A, Roose-Girma M, Dohse M, Komuves L, Webster JD, Dixit VM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "31511692", "url": "https://glygen.org/publication/PubMed/31511692" } ] }, { "title": "An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.", "journal": "Molecular cell", "date": "2020-01-16", "authors": "Odle Richard I, Walker Simon A, Oxley David, Kidger Andrew M, Balmanno Kathryn, Gilley Rebecca, Okkenhaug Hanneke, Florey Oliver, Ktistakis Nicholas T, Cook Simon J", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "31733992", "url": "https://glygen.org/publication/PubMed/31733992" } ] }, { "title": "VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPK\u03b11.", "journal": "Cells", "date": "2020-03-11", "authors": "Spengler Katrin, Kryeziu Nderim, Gro\u00dfe Silke, Mosig Alexander S, Heller Regine", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "32168879", "url": "https://glygen.org/publication/PubMed/32168879" } ] }, { "title": "The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death.", "journal": "Cell reports", "date": "2020", "authors": "Wu W, Wang X, Berleth N, Deitersen J, Wallot-Hieke N, Bohler P, Schlutermann D, Stuhldreier F, Cox J, Schmitz K, Seggewiss S, Peter C, Kasof G, Stefanski A, Stuhler K, Tschapek A, Godecke A, Stork B", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5357905" } ], "reference": [ { "type": "PubMed", "id": "32320653", "url": "https://glygen.org/publication/PubMed/32320653" } ] }, { "title": "TGF-\u03b2-activated kinase 1 (TAK1) mediates cadmium-induced autophagy in osteoblasts via the AMPK / mTORC1 / ULK1 pathway.", "journal": "Toxicology", "date": "2020-09", "authors": "Ran Di, Ma Yonggang, Liu Wei, Luo Tongwang, Zheng Jiaming, Wang Dedong, Song Ruilong, Zhao Hongyan, Zou Hui, Gu Jianhong, Yuan Yan, Bian Jianchun, Liu Zongping", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "32693121", "url": "https://glygen.org/publication/PubMed/32693121" } ] }, { "title": "DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy.", "journal": "Cell death and differentiation", "date": "2021-03", "authors": "Li Guan-Man, Li Lei, Li Meng-Qing, Chen Xu, Su Qiao, Deng Zhi-Juan, Liu Hai-Bo, Li Bin, Zhang Wen-Hui, Jia Yong-Xu, Wang Wen-Jian, Ma Jie-Yi, Zhang Hai-Liang, Xie Dan, Zhu Xiao-Feng, He Yu-Long, Guan Xin-Yuan, Bi Jiong", "evidence": [ { "database": "iPTMnet", "id": "O75385", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O75385" } ], "reference": [ { "type": "PubMed", "id": "33037394", "url": "https://glygen.org/publication/PubMed/33037394" } ] }, { "title": "MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL.", "journal": "Communications biology", "date": "2021", "authors": "Nakabayashi O, Takahashi H, Moriwaki K, Komazawa-Sakon S, Ohtake F, Murai S, Tsuchiya Y, Koyahara Y, Saeki Y, Yoshida Y, Yamazaki S, Tokunaga F, Sawasaki T, Nakano H", "evidence": [ { "database": "Reactome", "id": "R-HSA-5357905", "url": 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"MEPGRGGLEVVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPNNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASAAVKKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQQLQKTLTSPADAAGFLQGSRDSGGSSKDSSCDTDDFVMVPAQFPGDLVADAACAKPPPDSLMCSGSSLAASAGPESRGRTPSPSPPCSSSLSPSGRAGAFSSSRCGASVPIPVPTQVQNYQRIEQNLQSPTQYQTARSSAIRRSGSTSPLGFARASPSPPSHAEHGAALARKLSLGGGRPYTPSPQVGTIPERPGWSGAPSPQAAEMRGGRSPRPGSSAPEHSPHTAGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGVAFGHPQASPPQPSHGLQSCRPLRGSPKLPDFLQRNPLPPILGSPTKAMPAFDFTKTPSSQNLLTFLARQGVVMTPPRNRTLPDLSEAGPFQGQPVGPGLRPTEDTKGPFGRSLSTGRLTDLLLKAAFGTQAPDSGSTDSLQEKPMEIAPSAGFGGNLHPGARAAGASSPSPVVFTVGSPPSGTTPPQGPRTTMFSVGSSSSLSSAGSSSARHLAPGAYSEATLEVPAPGHCCSFADPVTANLEGAVTFEAPDLPEETLMEQEHTEILHSLRFTLVFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKHVVRKLNELYKTSVVSCQGLSLRLQRFFLDKQRLLDRIQSVTAEKLIFSHAVQTVQSAALDEMFHRREDCVQRYHKALLLMEGLQQILTDQADVENIAKCKLCIERRLSALLSGICA", "length": 1055 }, "evidence": [ { "id": "O75385", "url": "https://omabrowser.org/oma/group/O75385/", "database": "OMA" } ], "common_name": "Pig" }, { "uniprot_canonical_ac": "O70405-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "Ulk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTTPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA", "length": 1051 }, "evidence": [ { "id": "45921790", "url": "http://www.informatics.jax.org/homology/45921790", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 26, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "regulation of macroautophagy", "id": "GO:0016241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016241", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "peptidyl-threonine phosphorylation", "id": "GO:0018107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018107", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "neuron projection regeneration", "id": "GO:0031102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031102", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "peptidyl-serine phosphorylation", "id": "GO:0018105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018105", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "late nucleophagy", "id": "GO:0044805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044805", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010803", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "negative regulation of collateral sprouting", "id": "GO:0048671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048671", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "regulation of protein lipidation", "id": "GO:1903059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903059", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "Atg1/ULK1 kinase complex", "id": "GO:1990316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990316", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "omegasome membrane", "id": "GO:1903349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903349", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1029, "end_pos": 1031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Autophosphorylated. Phosphorylated under nutrient-rich conditions; dephosphorylated during starvation or following treatment with rapamycin. Under nutrient sufficiency, phosphorylated by MTOR/mTOR, disrupting the interaction with AMPK and preventing activation of ULK1 (By similarity). In response to nutrient limitation, phosphorylated and activated by AMPK, leading to activate autophagy (PubMed:21205641, PubMed:25891078).", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "PubMed", "id": "21205641", "url": "https://glygen.org/publication/PubMed/21205641" }, { "database": "PubMed", "id": "25891078", "url": "https://glygen.org/publication/PubMed/25891078" } ] }, { "annotation": "Ubiquitinated via 'Lys-63'-linkage by a complex composed of AMBRA1 and TRAF6 following autophagy induction, promoting ULK1 stability and kinase activity. Deubiquitinated by USP20; leading to ULK1 stability and autophagy initiation (PubMed:29487085).", "evidence": [ { "database": "UniProtKB", "id": "O75385", "url": "https://www.uniprot.org/uniprot/O75385" }, { "database": "PubMed", "id": "29487085", "url": "https://glygen.org/publication/PubMed/29487085" }, { "database": "PubMed", "id": "23524951", "url": "https://glygen.org/publication/PubMed/23524951" } ] } ], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B2DD29-1", "D3ZML2-1", "O08875-1", "O35831-1", "D3ZHP7-1", "D4A280-1", "E9PTG8-1", "O35832-1", "O54748-1", "P57760-1", "Q62868-1", "D3ZBE5-1", "P59895-1", "O55099-1", "O88764-1", "P59241-1", "Q91XS8-1", "Q63644-1", "Q7TQP6-1", "Q9Z2P5-1", "P11345-1", "P11275-1", "F1LYY7-1", "Q9JIH7-1", "P14056-1", "P35426-1", 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"Q95SH0-1", "Q9VI84-1", "Q9VEN3-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B2DD29-1", "D3ZML2-1", "O08875-1", "O35831-1", "P57760-1", "D3ZHP7-1", "D4A280-1", "E9PTG8-1", "O35832-1", "O54748-1", "Q62868-1", "D3ZBE5-1", "P59895-1", "O55099-1", "O88764-1", "P59241-1", "Q91XS8-1", "Q63644-1", "Q7TQP6-1", "Q9Z2P5-1", "P11345-1", "P11275-1", "F1LYY7-1", "Q9JIH7-1", "Q5XIT0-1", "P14056-1", "P35426-1", "P51952-1", "P63086-1", "Q5U2X5-1", "Q63117-1", "F1M7Y5-1", "P08413-1", "P47196-1", "P47197-1", "P97874-1", "Q03114-1", "Q3MJK5-1", "Q09137-1", "Q4V8A3-1", "P54645-1", "Q63686-1", "P0C1X8-1", "P19139-1", "D4A7V9-1", "Q62915-1", "Q63184-1", "Q63484-1", "Q9Z1Z1-1", "O70444-1", "P0C0R5-1", "O08874-1", 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"Q80XP9-1", "Q4FZD7-1", "P83741-1", "Q3UH66-1", "Q80UE6-1", "O88351-1", "Q5U452-1", "Q9ES70-1", "Q9ES74-1", "P52480-1", "Q9JIX9-1", "A2AQX6-1", "J3QK59-1", "Q3UT86-1", "A0A087WRH8-1", "A0A140LI04-1", "Q8BWE1-1", "J3KMT3-1", "A0A087WSF2-1", "Q3UTA8-1", "A0A140LJ87-1", "P13185-1", "P13186-1", "P14680-1", "P15442-1", "P15790-1", "P18961-1", "P19454-1", "P21965-1", "P22204-1", "P22216-1", "P22517-1", "P23292-1", "P23293-1", "P23561-1", "P25333-1", "P25341-1", "P25389-1", "P27466-1", "P27636-1", "P29295-1", "P32490-1", "P32600-1", "P32944-1", "P35169-1", "P36003-1", "P38615-1", "P40494-1", "P41695-1", "P43565-1", "P53894-1", "P53974-1", "Q03497-1", "Q12263-1", "P00546-1", "P05986-1", "P06243-1", "P06244-1", "P06245-1", "P06782-1", "P06784-1", "P08018-1", "P08458-1", "P11792-1", "P12688-1", "P14681-1", "P16892-1", "P17157-1", "P22211-1", "P23291-1", "P24583-1", "P32485-1", "P32562-1", "P39009-1", "P40160-1", "P41808-1", "P43568-1", "P48562-1", "P53233-1", "P53739-1", "Q00772-1", "Q03407-1", 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"Q54MH0-1", "Q54MV2-1", "Q54P26-1", "Q54PK8-1", "Q54PX0-1", "Q54QD5-1", "Q54R95-1", "Q54RB2-1", "Q54RJ4-1", "Q54RR9-1", "Q54RV3-1", "Q54RZ7-1", "Q54SC4-1", "Q54SK3-1", "Q54TA3-1", "Q54TH6-1", "Q54TN4-1", "Q54U31-1", "Q54U65-1", "Q54UA9-1", "Q54UZ1-1", "Q54V35-1", "Q54V83-1", "Q54VC0-1", "Q54VU4-1", "Q54VV7-1", "Q54WC0-1", "Q54WD7-1", "Q54WE5-1", "Q54WW7-1", "Q54XJ4-1", "Q54XX5-1", "Q54XY6-1", "Q54XZ5-1", "Q54Y06-1", "Q54Y55-1", "Q54Y90-1", "Q54YZ5-1", "Q54ZN3-1", "Q552C1-1", "Q552E9-1", "Q552Z2-1", "Q553E9-1", "Q556J6-1", "Q559A2-1", "Q559T8-1", "Q55A09-1", "Q55A55-1", "Q55BA0-1", "Q55CA6-1", "Q55CE0-1", "Q55CW2-1", "Q55CW3-1", "Q55DJ9-1", "Q55DK2-1", "Q55DU7-1", "Q55EI8-1", "Q55F45-1", "Q55FV4-1", "Q55FV5-1", "Q55GC2-1", "Q55GE6-1", "Q55GS4-1", "Q55GU0-1", "Q6XHA7-1", "Q75JN1-1", "Q76P07-1", "Q869L4-1", "Q869T7-1", "Q869X3-1", "Q86A12-1", "Q86HG9-1", "Q86HW6-1", "Q86I06-1", "Q8MYF1-1", "Q8SSV3-1", "Q9NGW9-1", "P0CD62-1", "P34100-1", "P34102-1", "P34103-1", "Q1ZXC8-1", "Q1ZXH2-1", "Q1ZXI5-1", "Q1ZXR2-1", "Q23915-1", "Q54HS0-1", "O61122-1", "O61125-1", "P28178-1", "P34099-1", "P34101-1", "P34112-1", "P34117-1", "P42525-1", "P54644-1", "P54685-1", "Q02720-1", "Q1ZXD6-1", "Q54B33-1", "Q54B48-1", "Q54BC9-1", "Q54BF0-1", "Q54C18-1", "Q54C71-1", "Q54D75-1", "Q54DC8-1", "Q54DF2-1", "Q54DK3-1", "Q54EG9-1", "Q54EY4-1", "Q54GY6-1", "Q54H45-1", "Q54H46-1", "Q54HC6-1", "Q54I36-1", "Q54IE8-1", "Q54JC7-1", "Q54JG7-1", "Q54LR6-1", "Q54M77-1", "Q54MY9-1", "Q54P47-1", "Q54PK9-1", "Q54Q69-1", "Q54QB1-1", "Q54QI2-1", "Q54QQ1-1", "Q54QV3-1", "Q54R82-1", "Q54RB7-1", "Q54S77-1", "Q54T05-1", "Q54TA1-1", "Q54TM7-1", "Q54TW2-1", "Q54UC0-1", "Q54UL8-1", "Q54VD8-1", "Q54VI1-1", "Q54W07-1", "Q54WJ0-1", "Q54WS5-1", "Q54WX4-1", "Q54XL6-1", "Q54XQ2-1", "Q54Y26-1", "Q54YF2-1", "Q550K8-1", "Q550L8-1", "Q551H4-1", "Q552C6-1", "Q556Q3-1", "Q556S2-1", "Q556Y4-1", "Q557G1-1", "Q558U1-1", "Q55BN8-1", "Q55CL6-1", "Q55CY9-1", "Q55CZ1-1", "Q55D99-1", "Q55DD4-1", "Q55DJ8-1", "Q55E58-1", "Q55EC7-1", "Q55FS2-1", "Q55FT4-1", "Q55GJ2-1", "Q55GV3-1", "Q5VJL3-1", "Q6B9X6-1", "Q6XHA5-1", "Q6XHB2-1", "Q75JK0-1", "Q76NV1-1", "Q869N2-1", "Q86AE1-1", "Q86AT8-1", "Q86C65-1", "Q86CS2-1", "Q86HN7-1", "Q86IX1-1", "Q8MVR1-1", "Q8SSS9-1", "Q8SSY6-1", "Q8T2I8-1", "Q95YH0-1", "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83098-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "A0A0B4KHX7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "M9PI41-1", "Q9VM90-1", "A1ZBL9-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P49762-1", "P54367-1", "P83099-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "Q9NIV1-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "P54360-1", "Q9VT57-1", "Q9VI13-1", "A1ZBC4-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "Q7PLI7-1", "X2JAG8-1", "O61661-1", "A4VCL2-2", "A0A0B4KHT3-1", "A0A4D6K823-1", "Q9VP22-1", "Q9VZI2-1", "Q9W1B0-1", "Q9V3I5-1", "A1ZBH7-1", "Q9W002-1", "Q9VRJ6-1", "Q8T9L5-1", "Q94533-1", "Q9VUQ9-1", "Q9VXE3-1", "Q9VGF9-1", "Q9VBU2-1", "Q9VR42-1", "Q9VW24-1", "A0A0B4KHC3-1", "Q9VL34-1", "Q9VTL5-1", "Q95TN8-1", "Q9VCV0-1", "Q8MSQ4-1", "Q9VE06-1", "Q9VJ30-1", "Q9VXN5-1", "M9PGC5-1", "Q9VN23-1", "M9NGC6-1", "O61444-1", "O62602-1", "Q9VUV4-1", "Q9VMY8-1", "Q9VD82-1", "A0A6M3Q7C8-1", "Q9W3N8-1", "Q95SH0-1", "Q9VJC2-1", "Q9VI84-1", "Q9VEN3-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-HSA-1632857", "name": "ULK1 phosphorylates AMBRA1:BECN1 complex", "equation": "", "summary": "Upon autophagy induction, ULK1 phosphorylates AMBRA1, which leads to the release of the Beclin-1 complex from the dynein motor complex (Di Bartolomeo et al. 2010).", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q99570-1", "P54646-1", "Q13131-1", "O75385-1", "Q8NEB9-1" ], "evidence": [ { "id": "R-HSA-1632857", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1632857" } ] }, { "id": "R-HSA-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "equation": "", "summary": "In mammals, the ULK complex and the class III PI3 Kinase containing Beclin-1 complex jointly produce the phagophore membrane, the initial phase of autophagosome formation (Karanosis et al. 2013). It is not fully understood how ULK1 is modulated in response to environmental cues. Phosphorylation plays an essential role (Dunlop & Tee 2013), but it is not clear how phosphorylation of ULK1 (or ATG13) leads to regulation (Ravikumar et al. 2010). Nor is it clear what ULK1 kinase activity achieves, it is not required for formation of the core complex but may be important for the recruitment of other proteins or have a direct role in subsequent autophagosome formation. Exactly how the ULK1 complex transduces upstream signals to the downstream central autophagy pathway is unclear (Wong et al. 2013).

At least 30 phosphorylation sites have been identified on ULK1, although the majority of the responsible kinases and the functions of these phosphorylation events remain to be identified (Dorsey et al. 2009, Mack et al. 2012). During glucose starvation, several sites in human ULK1 (Ser-317 - Kim et al. 2011, S467, S556, T575, and S638 - Egan et al. 2011) are reported to be phosphorylated by AMPK and required for efficient autophagy (Kim et al. 2011, Egan et al. 2011). These five phosphorylations are annotated here.

ULK1 phosphorylation activates its kinase activity and leads to the inhibition of mTORC1, via phosphorylation of TSC2 and raptor (Kim et al. 2011). Two AMPK phosphorylation sites in ULK1 (S556 and T575) also appear to be 14-3-3 binding sites.", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P54646-1", "Q13131-1", "O75385-1" ], "evidence": [ { "id": "R-HSA-5665868", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5665868" } ] }, { "id": "R-HSA-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "equation": "", "summary": "ULK1 phosphorylation activates its kinase activity and leads to the inhibition of mTORC1, via phosphorylation of TSC2 and raptor (Kim et al. 2011). Thr-180 in the activation loop of the catalytic centre of ULK1 is required for ULK1 kinase activity. This is suggested to be an autophosphorylation site, though the existence of an upstream kinase was not ruled out (Bach et al. 2011). A homologous site in yeast Atg1 is similarly required for kinase activity and suggested to be autophosphorylated (Yeh et al. 2010). Ser-1047 at the extreme C-terminal end of mouse ULK1 was proposed to be the main Ulk1 autophosphorylation site (Dorsey et al. 2009); the equivalent residue in human ULK1 is Thr-1046. ULK1-mediated phosphorylations of ATG13, FIP200, and ULK1 itself triggers autophagy (Mizushima et al. 2011).", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P54646-1", "Q13131-1", "O75385-1" ], "evidence": [ { "id": "R-HSA-5672008", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5672008" } ] }, { "id": "R-HSA-5672010", "name": "Active MTORC1 phosphorylates ULK1", "equation": "", "summary": "Under nutrient-rich conditions, mTORC1 phosphorylates ULK1 on S758 (Kim et al. 2011, Egan et al. 2011). ULK1 phosphorylation correlates with autophagy inhibition and reduced ULK1 kinase activity (Jung et al. 2009, Ganley et al. 2009, Hosakawa et al. 2009). RB1CC1 (FIP200) is probably phosphorylated (Mizushima 2010). ULK1 phosphorylation on S758 disrupts interaction between ULK1 and AMPK, thereby preventing AMPK from phosphorylating ULK1 at activating sites (Jung et al. 2009, Kim et al. 2011, Egan et al. 2011). If phosphorylation of ULK1 complex components suppresses autophagy, activation might be expected to involve more than suppression of kinases such as mTORC1. The phosphatase inhibitor okadaic acid inhibits autophagy (Blankson et al. 1995) but the protein phosphatase(s) involved in ULK1 dephosphorylation are currently unknown (Wong et al. 2013).", "cellular_location": "lysosomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P42345-1", "O75385-1", "Q15382-1", "Q5VZM2-1", "Q9HB90-1", "Q9NQL2-1", "Q7L523-1" ], "evidence": [ { "id": "R-HSA-5672010", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5672010" } ] }, { "id": "R-HSA-5672011", "name": "p-AMPK:AMP binds the ULK complex", "equation": "", "summary": "The heterotrimeric AMPK kinase complex, when bound to AMP, binds strongly to the ULK1 kinase complex. Rapamycin increases the co-immunoprecipitation of AMPK and ULK1, suggesting that mTORC1 activity may regulate their association. mTORC1 phosphorylates ULK1 on S758 and this phosphorylation disrupts the interaction between ULK1 and AMPK (Kim et al. 2011, Egan et al. 2011), suggesting that under nutrient-rich conditions, active mTORC1 phosphorylates ULK1 to disrupt ULK1-AMPK interaction, which keeps ULK1 inactive.

When cellular energy is depleted, AMPK is activated and inhibits mTORC1 via phosphorylation of TSC2 and raptor, thereby, reducing S758 phosphorylation on ULK1. The S758 unphosphorylated ULK1 is able to associate with, and be activated by, AMPK (Egan et al. 2011). This coordinated phosphorylation of ULK1 by mTORC1 and AMPK may provide a mechanism by which cells can properly respond to a wide range of stimuli.

ULK1 was identified as the mammalian homologue of yeast Atg1 (Kuroyanagi et al. 1998, Chan et al. 2007). It functions in a complex with ATG13 (KIAA0652) and RB1CC1 (FIP200), this considered to be the core ULK complex, which associates with ATG101 (Hosokawa et al. 2009, Jung et al. 2009, Ganley et al. 2009, Mercer et al. 2009). ATG13 binds ULK1 (and ULK2), mediating the interaction with RB1CC1. All four components of this complex are essential for autophagy induction and predominantly localized to the cytosol, associating with the isolation membrane upon autophagy induction (Mizushima 2011). RB1CC1 in this complex can interact with many other proteins including Pyk2, FAK, TSC1, p53, ASK1, and TRAF2 (Gan & Guan 2008).", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P54646-1", "Q13131-1", "O75385-1" ], "evidence": [ { "id": "R-HSA-5672011", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5672011" } ] }, { "id": "R-HSA-5672817", "name": "Active MTORC1 binds the ULK1 complex", "equation": "", "summary": "Under nutrient-rich conditions, the mTORC1 complex associates with the ULK complex (Mizushima 2010). Binding is mediated by Raptor, a substrate recognition subunit of mTORC1, and the PS domain of ULK1 (Hosokawa et al. 2009).

Active mTORC1 phosphorylates ULK1 Ser-758, which disrupts the interaction between ULK1 and AMPK, thereby maintaining ULK1 in an inactive state (Jung et al. 2009, Kim et al. 2011, Egan et al. 2011).

When cellular energy is depleted, AMPK is activated. It inhibits mTORC1 kinase activity via phosphorylation of both TSC2 and raptor (Gwinn et al. 2008). Inhibition of mTORC1 reduces S758 phosphorylation on ULK1 (Shang et al. 2011). The S758-unphosphorylated ULK1 is able to associate with, and be activated by, AMPK.", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P42345-1", "O75385-1", "Q15382-1", "Q5VZM2-1", "Q9HB90-1", "Q9NQL2-1", "Q7L523-1" ], "evidence": [ { "id": "R-HSA-5672817", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5672817" } ] }, { "id": "R-HSA-5673768", "name": "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex", "equation": "", "summary": "When cellular energy is depleted, the active AMPK complex (bound to AMPK, AMPK alpha phosphorylated on Thr-172 or Thr-174) phosphorylates the mTORC1 component RPTOR (Raptor) on Ser-722 and Ser-792. These phosphorylations are required for inhibition of mTORC1 activity in response to energy stress (Gwinn et al. 2008), and are believed to promote the dissociation of mTORC1 from the ULK1 complex (Wong et al. 2013). This reduces mTORC1 phosphorylation of ULK1 Ser-758, which consequently is able to associate with, and be activated by, AMPK (Egan et al. 2011). This coordinated phosphorylation of ULK1 by mTORC1 and AMPK may provide a mechanism by which cells can properly respond to a wide range of stimuli.", "cellular_location": "cytosol, lysosomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P54646-1", "Q13131-1", "P42345-1", "O75385-1", "Q15382-1", "Q5VZM2-1", "Q9HB90-1", "Q9NQL2-1", "Q7L523-1" ], "evidence": [ { "id": "R-HSA-5673768", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5673768" } ] }, { "id": "R-HSA-5675790", "name": "MTORC1 dissociates from ULK complex", "equation": "", "summary": "When cellular energy is depleted mTORC1 dissociates from the ULK1 complex (Hosakawa et al. 2009, Lee et al. 2010, Wong et al. 2013). The phosphorylation of RPTOR (Raptor) by AMPK promotes the dissociation of mTORC1 from the ULK1 complex, which leads to a reduction in S758 phosphorylation on ULK1 (Shang et al. 2011). The S758-unphosphorylated ULK1 is able to associate with, and be activated by, AMPK (Egan et al. 2011).", "cellular_location": "cytosol, endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P42345-1", "O75385-1", "Q15382-1", "Q5VZM2-1", "Q9HB90-1", "Q9NQL2-1", "Q7L523-1" ], "evidence": [ { "id": "R-HSA-5675790", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5675790" } ] }, { "id": "R-HSA-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "equation": "", "summary": "ULK1 (and ULK2) can phosphorylate both ATG13 and RB1CC1 (Hosakawa et al. 2009, Jung et al. 2009). Similarly Drosophila Atg1, the orthologue of ULK1, phosphorylates Drosophila Atg13 (Chang & Neufeld 2009). This phosphorylation is believed to be activating, opposing the inactivating phosphorylation of ATG13 by mTORC1 (Kamada et al. 2000, Hosakawa et al. 2009,Chang & Neufeld 2009, Jung et al. 2009) under conditions of nutrient sufficiency.", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P54646-1", "Q13131-1", "O75385-1" ], "evidence": [ { "id": "R-HSA-5675868", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5675868" } ] }, { "id": "R-HSA-5679205", "name": "ULK1 phosphorylates Beclin-1", "equation": "", "summary": "Following amino-acid starvation or mTOR inhibition, activated ULK1 phosphorylates BECN1 (Beclin-1) on Ser-15, thereby enhancing the activity of PIK3C3 (Vps34) in the Beclin-1 complex. This phosphorylation is required for full autophagic induction in mammals (Russell et al. 2013).", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q99570-1", "P54646-1", "Q13131-1", "O75385-1", "Q8NEB9-1" ], "evidence": [ { "id": "R-HSA-5679205", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5679205" } ] }, { "id": "R-HSA-5679239", "name": "ULK complex translocates to the ER", "equation": "", "summary": "The ULK complex is recruited to the membrane site of phagophore nucleation, which is likely to be a pre-existing ER structure containing the multi-membrane spanning protein vacuole membrane protein 1 (VMP1) (Wirth et al. 2013, Koyama-Honda et al. 2013). This may be mediated by the C-terminal early autophagy targeting/tethering (EAT) domain of ULK1, which appears to be essential for recruitment to the site of phagophore nucleation (Chan et al. 2009, Ragusa et al. 2012). The N-terminus of the ATG13 component of the ULK complex may also contribute to membrane association as it can interact with acidic phospholipids and is required for the translocation of ATG13 to omegasomes (Karanasios et al. 2013).", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P54646-1", "Q13131-1", "O75385-1" ], "evidence": [ { "id": "R-HSA-5679239", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5679239" } ] }, { "id": "R-HSA-5683925", "name": "ULK1 is dephosphorylated", "equation": "", "summary": "Under starvation conditions ULK1 undergoes dephosphorylation, particularly at serine-639 and serine-758 (Shang et al. 2011). The S757 unphosphorylated ULK1 is able to associate with, and be activated by, AMPK (Egan et al. 2011). The protein phosphatase(s) involved in ULK1 dephosphorylation are currently unknown (Wong et al. 2013).", "cellular_location": "cytosol", "input_participant_list": [ "R-HSA-5672130" ], "output_participant_list": [ "R-HSA-5666059" ], "enzyme_list": [ "O75385-1" ], "evidence": [ { "id": "R-HSA-5683925", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5683925" } ] }, { "id": "R-HSA-8854759", "name": "TBC1D14 binds RAB11 and ULK1", "equation": "", "summary": "TBC (Tre2/Bub2/Cdc16) domain family, member 14 (TBC1D14) is a putative Rab GTPase activating protein (GAP) member that binds to activated Rab11 and regulates starvation-induced autophagy. TBC1D14 does not have the GAP activity and may function as Rab11 effector. TBC1D14 also colocalizes and interacts with the autophagy kinase ULK1. Overexpression of TBC1D14 causes tubulation of recycling endosomes (REs), accumulation of the ULK1 complex and Rab11 on REs, and inhibition of vesicular transport from the RE (Longatti et al. 2012).", "cellular_location": "recycling endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P62491-1", "O75385-1", "Q15907-1" ], "evidence": [ { "id": "R-HSA-8854759", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8854759" } ] }, { "id": "R-HSA-8876446", "name": "p-ULK1 phosphorylates DENND3", "equation": "", "summary": "ULK1 is a serine-threonine kinase with key roles in macroautophagy in response to starvation. Under high nutrient conditions, ULK1 is phosphorylated by mTORC1, inhibiting the autophagy pathway, while under nutrient-limited conditions, mTORC1 phosphorylation is replaced by AMPK-mediated phosphorylation, resulting in the activation of both ULK1 and the autophagy pathway (reviewed in Wong et al, 2013). How nutrient levels are sensed by mTORC1 and ULK1 is not fully established, but a number of recent papers have highlighted a role for RAB proteins and their regulators in autophagy (Matsui and Fukuda, 2013; Matsui et al, 2014; Xu et al, 2015; Fan et al, 2016; reviewed in Lamb et al, 2013; Xu and McPherson, 2015). Under starvation conditions, ULK1 phosphorylates DENND3, a RAB12 GEF, at serine residues 472 and 490, activating it and promoting the formation of GTP-bound RAB12 (Yoshimura et al, 2010; Xu et al, 2015). Active RAB12 promotes the constitutive recycling or degradation of a number of plasma membrane proteins including the amino acid transporter SLC36A4 (also known as PAT4). Degradation of SLC36A4 decreases the intracellular amino acid concentration, inactivating mTORC1 and promoting the macroautophagy pathway (Matsui et al, 2011; Matsui and Fukuda, 2013; Xu et al, 2015; Fan et al, 2016).", "cellular_location": "cytosol", "input_participant_list": [ "R-HSA-8876435" ], "output_participant_list": [ "R-HSA-8876434" ], "enzyme_list": [ "O75385-1" ], "evidence": [ { "id": "R-HSA-8876446", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8876446" } ] }, { "id": "R-HSA-8948136", "name": "ULK1 Translocates to the mitochondria", "equation": "", "summary": "ULK1 is critical for the induction of autophagy, translocating to fragmented mitochondria upon mitophagy induction by either hypoxia or mitochondrial uncouplers. At mitochondria, ULK1 interacts with FUNDC1.", "cellular_location": "mitochondrial outer membrane", "input_participant_list": [ "R-HSA-1632847" ], "output_participant_list": [ "R-HSA-8948145" ], "enzyme_list": [ "O75385-1" ], "evidence": [ { "id": "R-HSA-8948136", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8948136" } ] }, { "id": "R-HSA-8948146", "name": "FUNDC1 is phosphorylated by ULK1 at Ser17", "equation": "", "summary": "At mitochondria, ULK1 interacts with FUNDC1, phosphorylating it at serine 17, which enhances FUNDC1 binding to LC3. FUNDC1 regulates ULK1 recruitment to damaged mitochondria; FUNDC1 phosphorylation by ULK1 is crucial for mitophagy.", "cellular_location": "mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [ "R-HSA-8948140" ], "enzyme_list": [ "O75385-1" ], "evidence": [ { "id": "R-HSA-8948146", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8948146" } ] }, { "id": "R-HSA-9819106", "name": "ULK1 phosphorylates RIPK1 at S357", "equation": "", "summary": "Autophagy controls programmed cell death through different cross-talk signals (Bray K et al. 2012; Goodall ML et al. 2016; Lim J et al 2019; Wu W et al. 2020). For instance, serine/threonine kinase Unc-51-like kinase-1 (ULK1), an essential initiator of the autophagy response, regulates the tumor necrosis factor \u03b1 (TNF\u03b1)-induced signaling pathway (Wu W et al. 2020; reviewed in Zou L et al. 2022). TNF\u03b1 binds TNF receptor 1 (TNFR1) inducing the sequential formation of several signaling complexes, namely complex I and complex IIa/b (Micheau O and Tschopp J 2003; Walczak H 2011; Yuan J et al. 2019). These complexes support either cell survival (complex I) or cell death (complex II). Receptor-interacting serine/threonine protein kinase 1 (RIPK1) functions as a key regulator of the TNF:TNFR1 signaling pathway (reviewed in Ju E et al. 2022). The RIPK1 activity is tightly regulated by proteolysis, ubiquitination and phosphorylation (reviewed in Delanghe T et al. 2020; Ju E et al. 2022). RIPK1 was identified as a substrate of ULK1 (Wu W et al. 2020). ULK1 deficiency enhanced autophosphorylation of RIPK1 at S166 and association of RIPK1 with FADD in TNF-stimulated mouse fibroblast L929 and MEF cells (Wu W et al. 2020). Co-immunoprecipitation assay showed that ULK1 associated with RIPK1 upon co-expression of tagged proteins in human embryonic kidney 293 (HEK293) cells (Wu W et al. 2020). The interaction between endogenous ULK1 and RIPK1 was detected in TNF-stimulated L929 cells. The kinase activity of ULK1 was found to phosphorylate RIPK1 at S357 in HEK293 (Wu W et al. 2020). The ULK1-mediated phosphorylation of RIPK1 occurred preferentially in the cytosol preventing the formation of complex II (Wu W et al. 2020). These data suggest that ULK1 exerts a cytoprotective function by suppressing RIPK1-mediated cell death.

This Reactome event describes ULK1-mediated phosphorylation of RIPK1 at S357 within the cytosolic TRAF2:TRADD:RIPK1 complex.", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q12933-1", "O75385-1", "Q13546-1" ], "evidence": [ { "id": "R-HSA-9819106", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9819106" } ] } ], "reaction_participants": [ { "participant_id": "R-HSA-1632847", "participant_name": "ULK1 [cytosol]", "crossref": [ { "id": "O75385", "database": "UniProt", "url": "" }, { "id": "8SOI", "database": "PDB", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - Investigational", "url": "" }, { "id": "O75385", "database": "ZINC target", "url": "" }, { "id": "4WNO", "database": "PDB", "url": "" }, { "id": "NP_003556.1", "database": "RefSeq", "url": "" }, { "id": "ENSG00000177169", "database": "OpenTargets", "url": "" }, { "id": "2271", "database": "Guide to Pharmacology - Targets", "url": "" }, { "id": "HMDBP01330", "database": "HMDB Protein", "url": "" }, { "id": "8SRQ", "database": "PDB", "url": "" }, { "id": "6QAS", "database": "PDB", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - FDA approved", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - Predictions - Purchasable", "url": "" }, { "id": "8SRM", "database": "PDB", "url": "" }, { "id": "6HYO", "database": "PDB", "url": "" }, { "id": "ENST00000321867", "database": "Ensembl", "url": "" }, { "id": "O75385", "database": "Pharos - Targets", "url": "" }, { "id": "O75385", "database": "GeneCards", "url": "" }, { "id": "6MNH", "database": "PDB", "url": "" }, { "id": "4WNP", "database": "PDB", "url": "" }, { "id": "O75385", "database": "PRO", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - Biogenic", "url": "" }, { "id": "5CI7", "database": "PDB", "url": "" }, { "id": "8SQZ", "database": "PDB", "url": "" }, { "id": "ENSP00000324560", "database": "Ensembl", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - World Drugs", "url": "" }, { "id": "ENSG00000177169", "database": "Ensembl", "url": "" }, { "id": "ENSG00000177169-ULK1", "database": "HPA", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - Substances", "url": "" } ] }, { "participant_id": "R-HSA-5666059", "participant_name": "ULK1:ATG13:RB1CC1:ATG101 [cytosol]", "crossref": [ { "id": "CPX-373", "database": "ComplexPortal", "url": "" } ] }, { "participant_id": "R-HSA-5672130", "participant_name": "p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol]", "crossref": [ { "id": "CPX-373", "database": "ComplexPortal", "url": "" } ] }, { "participant_id": "R-HSA-8876434", "participant_name": "p-S472,S490-DENND3 [cytosol]", "crossref": [ { "id": "ENST00000424248", "database": "Ensembl", "url": "" }, { "id": "A2RUS2", "database": "PRO", "url": "" }, { "id": "NP_055772.2", "database": "RefSeq", "url": "" }, { "id": "A2RUS2", "database": "Pharos - Targets", "url": "" }, { "id": "ENSP00000262585", "database": "Ensembl", "url": "" }, { "id": "A2RUS2", "database": "UniProt", "url": "" }, { "id": "ENSP00000410594", "database": "Ensembl", "url": "" }, { "id": "ENSG00000105339", "database": "Ensembl", "url": "" }, { "id": "A2RUS2", "database": "GeneCards", "url": "" }, { "id": "ENSG00000105339", "database": "OpenTargets", "url": "" }, { "id": "ENST00000262585", "database": "Ensembl", "url": "" }, { "id": "ENSG00000105339-DENND3", "database": "HPA", "url": "" } ] }, { "participant_id": "R-HSA-8876435", "participant_name": "DENND3 [cytosol]", "crossref": [ { "id": "A2RUS2", "database": "UniProt", "url": "" }, { "id": "ENST00000262585", "database": "Ensembl", "url": "" }, { "id": "A2RUS2", "database": "Pharos - Targets", "url": "" }, { "id": "ENSG00000105339", "database": "Ensembl", "url": "" }, { "id": "ENST00000424248", "database": "Ensembl", "url": "" }, { "id": "ENSG00000105339", "database": "OpenTargets", "url": "" }, { "id": "ENSP00000262585", "database": "Ensembl", "url": "" }, { "id": "ENSP00000410594", "database": "Ensembl", "url": "" }, { "id": "A2RUS2", "database": "PRO", "url": "" }, { "id": "ENSG00000105339-DENND3", "database": "HPA", "url": "" }, { "id": "NP_055772.2", "database": "RefSeq", "url": "" }, { "id": "A2RUS2", "database": "GeneCards", "url": "" } ] }, { "participant_id": "R-HSA-8948140", "participant_name": "p-S17-FUNDC1 [mitochondrial outer membrane]", "crossref": [ { "id": "ENST00000378045", "database": "Ensembl", "url": "" }, { "id": "NP_776155.1", "database": "RefSeq", "url": "" }, { "id": "ENSG00000069509", "database": "Ensembl", "url": "" }, { "id": "Q8IVP5", "database": "PRO", "url": "" }, { "id": "ENSG00000069509-FUNDC1", "database": "HPA", "url": "" }, { "id": "Q8IVP5", "database": "GeneCards", "url": "" }, { "id": "Q8IVP5", "database": "UniProt", "url": "" }, { "id": "Q8IVP5", "database": "Pharos - Targets", "url": "" }, { "id": "5GMV", "database": "PDB", "url": "" }, { "id": "2N9X", "database": "PDB", "url": "" }, { "id": "ENSG00000069509", "database": "OpenTargets", "url": "" }, { "id": "ENSP00000367284", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-HSA-8948145", "participant_name": "ULK1 [mitochondrial outer membrane]", "crossref": [ { "id": "8SRM", "database": "PDB", "url": "" }, { "id": "NP_003556.1", "database": "RefSeq", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - Biogenic", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - World Drugs", "url": "" }, { "id": "8SRQ", "database": "PDB", "url": "" }, { "id": "8SOI", "database": "PDB", "url": "" }, { "id": "O75385", "database": "GeneCards", "url": "" }, { "id": "ENSG00000177169-ULK1", "database": "HPA", "url": "" }, { "id": "ENST00000321867", "database": "Ensembl", "url": "" }, { "id": "2271", "database": "Guide to Pharmacology - Targets", "url": "" }, { "id": "8SQZ", "database": "PDB", "url": "" }, { "id": "O75385", "database": "ZINC target", "url": "" }, { "id": "4WNP", "database": "PDB", "url": "" }, { "id": "ULK1_HUMAN", "database": "ZINC - FDA 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"activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A087WRH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WRH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A087WRH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WRH8" } ] } ] }, { "uniprot_ac": "A0A087WSA6", "gene_name": "Gm7358", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A087WSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A087WSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSA6" } ] } ] }, { "uniprot_ac": "A0A087WSF2", "gene_name": "Smok3c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A087WSF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A087WSF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSF2" } ] } ] }, { "uniprot_ac": "A0A0B4J2F2", "gene_name": "SIK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4J2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4J2F2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4J2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4J2F2" } ] } ] }, { "uniprot_ac": "A0A0B4KHC3", "gene_name": "PKD", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3" } ] } ] }, { "uniprot_ac": "A0A0B4KHT3", "gene_name": "Lrrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3" } ] } ] }, { "uniprot_ac": "A0A0B4KHX7", "gene_name": "Gcn2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHX7" } ] } ] }, { "uniprot_ac": "A0A0G2JUP3", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3" } ] } ] }, { "uniprot_ac": "A0A0G2JVL3", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JVL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JVL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3" } ] } ] }, { "uniprot_ac": "A0A0G2JWX7", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX7" } ] } ] }, { "uniprot_ac": "A0A0G2JXR8", "gene_name": "LOC100911229", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JXR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JXR8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JXR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JXR8" } ] } ] }, { "uniprot_ac": "A0A0G2JZW9", "gene_name": "ENSRNOG00000068522", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9" } ] } ] }, { "uniprot_ac": "A0A0G2K2T8", "gene_name": "RGD1565143", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2T8" } ] } ] }, { "uniprot_ac": "A0A0G2K344", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] } ] }, { "uniprot_ac": "A0A0G2K490", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K490" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K490" } ] } ] }, { "uniprot_ac": "A0A0G2K578", "gene_name": "AABR07068650.1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K578" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K578" } ] } ] }, { "uniprot_ac": "A0A0G2K5C7", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5C7" } ] } ] }, { "uniprot_ac": "A0A0G2K5L3", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K5L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K5L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3" } ] } ] }, { "uniprot_ac": "A0A0G2K6V9", "gene_name": "RGD1564409", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9" } ] } ] }, { "uniprot_ac": "A0A0G2KAH6", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2KAH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2KAH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6" } ] } ] }, { "uniprot_ac": "A0A0G2KB60", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2KB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2KB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KB60" } ] } ] }, { "uniprot_ac": "A0A0G2QC55", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2QC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2QC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55" } ] } ] }, { "uniprot_ac": "A0A140LI04", "gene_name": "Gm5890", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A140LI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LI04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A140LI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LI04" } ] } ] }, { "uniprot_ac": "A0A140LJ87", "gene_name": "Gm4565", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A140LJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LJ87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A140LJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LJ87" } ] } ] }, { "uniprot_ac": "A0A3B2WD63", "gene_name": "Gm7356", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A3B2WD63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3B2WD63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3B2WD63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3B2WD63" } ] } ] }, { "uniprot_ac": "A0A4D6K823", "gene_name": "nmo", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K823" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K823" } ] } ] }, { "uniprot_ac": "A0A6M3Q7C8", "gene_name": "SRPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A6M3Q7C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A6M3Q7C8" } ] } ] }, { "uniprot_ac": "A0A8I5Y7S3", "gene_name": "LOC120097771", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5Y7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7S3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5Y7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7S3" } ] } ] }, { "uniprot_ac": "A0A8I5Y8C3", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5Y8C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5Y8C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8C3" } ] } ] }, { "uniprot_ac": "A0A8I5ZKJ9", "gene_name": "ENSRNOG00000070867", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZKJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZKJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKJ9" } ] } ] }, { "uniprot_ac": "A0A8I5ZLV4", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLV4" } ] } ] }, { "uniprot_ac": "A0A8I5ZMP0", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP0" } ] } ] }, { "uniprot_ac": "A0A8I5ZN46", "gene_name": "LOC108353138", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN46" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN46" } ] } ] }, { "uniprot_ac": "A0A8I5ZNK2", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZNK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZNK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNK2" } ] } ] }, { "uniprot_ac": "A0A8I5ZP97", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8I5ZP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97" } ] } ] }, { "uniprot_ac": "A0A8I5ZR62", "gene_name": "RGD1565071", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] } ] }, { "uniprot_ac": "A0A8I5ZS27", "gene_name": "LOC102555239", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZS27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZS27" } ] } ] }, { "uniprot_ac": "A0A8I5ZSS7", "gene_name": "LOC102546375", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSS7" } ] } ] }, { "uniprot_ac": "A0A8I5ZT61", "gene_name": "LOC300308", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT61" } ] } ] }, { "uniprot_ac": "A0A8I5ZUS1", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUS1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8I5ZUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUS1" } ] } ] }, { "uniprot_ac": "A0A8I5ZUX6", "gene_name": "RGD1566007", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZUX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZUX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUX6" } ] } ] }, { "uniprot_ac": "A0A8I5ZV60", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV60" } ] } ] }, { "uniprot_ac": "A0A8I5ZYM4", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] } ] }, { "uniprot_ac": "A0A8I5ZZZ6", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZZZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZZZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ6" } ] } ] }, { "uniprot_ac": "A0A8I6A0F8", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A0F8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A0F8" } ] } ] }, { "uniprot_ac": "A0A8I6A165", "gene_name": "LOC120093114", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A165" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A165" } ] } ] }, { "uniprot_ac": "A0A8I6A1U5", "gene_name": "LOC120093094", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1U5" } ] } ] }, { "uniprot_ac": "A0A8I6A574", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A574" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A574" } ] } ] }, { "uniprot_ac": "A0A8I6A7D1", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A7D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A7D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7D1" } ] } ] }, { "uniprot_ac": "A0A8I6A7V5", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7V5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8I6A7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7V5" } ] } ] }, { "uniprot_ac": "A0A8I6A8U4", "gene_name": "ENSRNOG00000066428", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A8U4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A8U4" } ] } ] }, { "uniprot_ac": "A0A8I6A9X0", "gene_name": "LOC120100104", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A9X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A9X0" } ] } ] }, { "uniprot_ac": "A0A8I6AAX5", "gene_name": "LOC120099682", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AAX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AAX5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AAX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AAX5" } ] } ] }, { "uniprot_ac": "A0A8I6ACE8", "gene_name": "LOC100910657", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACE8" } ] } ] }, { "uniprot_ac": "A0A8I6ACR1", "gene_name": "ENSRNOG00000067256", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ACR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACR1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ACR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACR1" } ] } ] }, { "uniprot_ac": "A0A8I6AD01", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AD01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AD01" } ] } ] }, { "uniprot_ac": "A0A8I6AEL0", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AEL0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8I6AEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AEL0" } ] } ] }, { "uniprot_ac": "A0A8I6AHQ6", "gene_name": "Nek2l1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AHQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AHQ6" } ] } ] }, { "uniprot_ac": "A0A8I6AJD2", "gene_name": "LOC103690174", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AJD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AJD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJD2" } ] } ] }, { "uniprot_ac": "A0A8I6AJX5", "gene_name": "RGD1561440", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJX5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8I6AJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJX5" } ] } ] }, { "uniprot_ac": "A0A8I6ANX6", "gene_name": "Dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ANX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ANX6" } ] } ] }, { "uniprot_ac": "A0A8I6AQN6", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQN6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQN6" } ] } ] }, { "uniprot_ac": "A0A8I6ATH0", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ATH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ATH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATH0" } ] } ] }, { "uniprot_ac": "A0A8I6ATM1", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ATM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATM1" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8I6ATM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATM1" } ] } ] }, { "uniprot_ac": "A0A8I6AUJ4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AUJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AUJ4" } ] } ] }, { "uniprot_ac": "A0A8I6AWX7", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8I6AWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7" } ] } ] }, { "uniprot_ac": "A0A8I6G1H3", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G1H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G1H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3" } ] } ] }, { "uniprot_ac": "A0A8I6G5Z0", "gene_name": "AABR07072539.5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Z0" } ] } ] }, { "uniprot_ac": "A0A8I6G980", "gene_name": "LOC100911984", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G980" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G980" } ] } ] }, { "uniprot_ac": "A0A8I6GBQ0", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GBQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GBQ0" } ] } ] }, { "uniprot_ac": "A0A8I6GDY5", "gene_name": "RGD1564651", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GDY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GDY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GDY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GDY5" } ] } ] }, { "uniprot_ac": "A0A8I6GI15", "gene_name": "RGD1560718", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GI15" } ] } ] }, { "uniprot_ac": "A0A8I6GJV1", "gene_name": "ENSRNOG00000069390", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJV1" } ] } ] }, { "uniprot_ac": "A0A8I6GK16", "gene_name": "LOC102549716", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK16" } ] } ] }, { "uniprot_ac": "A0A8I6GK52", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK52" } ] } ] }, { "uniprot_ac": "A0A8I6GKS8", "gene_name": "LOC120093063", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKS8" } ] } ] }, { "uniprot_ac": "A0A8I6GM03", "gene_name": "LOC685793", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GM03" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GM03" } ] } ] }, { "uniprot_ac": "A0A8J8XEH6", "gene_name": "ENSRNOG00000067334", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8J8XEH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8J8XEH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8J8XEH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8J8XEH6" } ] } ] }, { "uniprot_ac": "A0AUV4", "gene_name": "Gm7168", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0AUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0AUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0AUV4" } ] } ] }, { "uniprot_ac": "A1A5Q6", "gene_name": "Smok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1A5Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1A5Q6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1A5Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1A5Q6" } ] } ] }, { "uniprot_ac": "A1Z7T0", "gene_name": "Pkn", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] } ] }, { "uniprot_ac": "A1Z9X0", "gene_name": "aPKC", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z9X0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z9X0" } ] } ] }, { "uniprot_ac": "A1ZBC4", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] } ] }, { "uniprot_ac": "A1ZBH7", "gene_name": "hppy", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBH7" } ] } ] }, { "uniprot_ac": "A1ZBL9", "gene_name": "par-1", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] } ] }, { "uniprot_ac": "A2AAJ9", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AAJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AAJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2AAJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AAJ9" } ] } ] }, { "uniprot_ac": "A2AQW0", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQW0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2AQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQW0" } ] } ] }, { "uniprot_ac": "A2AQX6", "gene_name": "Gm14151", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AQX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2AQX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQX6" } ] } ] }, { "uniprot_ac": "A2ASS6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2ASS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ASS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2ASS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ASS6" } ] } ] }, { "uniprot_ac": "A2CG49", "gene_name": "Kalrn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2CG49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2CG49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2CG49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2CG49" } ] } ] }, { "uniprot_ac": "A2KF29", "gene_name": "Smoktcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2KF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2KF29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2KF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2KF29" } ] } ] }, { "uniprot_ac": "A4L9P5", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A4L9P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4L9P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4L9P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4L9P5" } ] } ] }, { "uniprot_ac": "A4VCL2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4VCL2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4VCL2" } ] } ] }, { "uniprot_ac": "A6HK01", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A6HK01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HK01" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A6HK01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HK01" } ] } ] }, { "uniprot_ac": "A6KB61", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A6KB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KB61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A6KB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KB61" } ] } ] }, { "uniprot_ac": "B0G126", "gene_name": "pip5k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] } ] }, { "uniprot_ac": "B0LT89", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B0LT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0LT89" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0LT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0LT89" } ] } ] }, { "uniprot_ac": "B1WBT4", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B1WBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B1WBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBT4" } ] } ] }, { "uniprot_ac": "B1WBU5", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B1WBU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B1WBU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBU5" } ] } ] }, { "uniprot_ac": "B2DD29", "gene_name": "Brsk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] } ] }, { "uniprot_ac": "B2GUY1", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B2GUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUY1" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "B2GUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUY1" } ] } ] }, { "uniprot_ac": "B5DFG1", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B5DFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B5DFG1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B5DFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B5DFG1" } ] } ] }, { "uniprot_ac": "C0HKC8", "gene_name": "Smok3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "C0HKC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C0HKC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC8" } ] } ] }, { "uniprot_ac": "C0HKC9", "gene_name": "Smok3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "C0HKC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C0HKC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC9" } ] } ] }, { "uniprot_ac": "D3Z822", "gene_name": "Atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z822" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z822" } ] } ] }, { "uniprot_ac": "D3Z837", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z837" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z837" } ] } ] }, { "uniprot_ac": "D3Z8E0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8E0" } ] } ] }, { "uniprot_ac": "D3Z8I4", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8I4" } ] } ] }, { "uniprot_ac": "D3ZBE5", "gene_name": "Nek7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZBE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBE5" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "D3ZBE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBE5" } ] } ] }, { "uniprot_ac": "D3ZBS8", "gene_name": "LOC690235", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZBS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZBS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBS8" } ] } ] }, { "uniprot_ac": "D3ZCD7", "gene_name": "Tp53rkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZCD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZCD7" } ] } ] }, { "uniprot_ac": "D3ZD18", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD18" } ] } ] }, { "uniprot_ac": "D3ZDM6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZDM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDM6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "D3ZDM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDM6" } ] } ] }, { "uniprot_ac": "D3ZEK4", "gene_name": "Tssk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEK4" } ] } ] }, { "uniprot_ac": "D3ZFL3", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZFL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFL3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZFL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFL3" } ] } ] }, { "uniprot_ac": "D3ZG83", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG83" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG83" } ] } ] }, { "uniprot_ac": "D3ZGQ5", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZGQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZGQ5" } ] } ] }, { "uniprot_ac": "D3ZHL6", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHL6" } ] } ] }, { "uniprot_ac": "D3ZHP7", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHP7" } ] } ] }, { "uniprot_ac": "D3ZJ84", "gene_name": "Tssk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJ84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJ84" } ] } ] }, { "uniprot_ac": "D3ZL21", "gene_name": "Tp53rka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZL21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZL21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZL21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZL21" } ] } ] }, { "uniprot_ac": "D3ZMG0", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZMG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZMG0" } ] } ] }, { "uniprot_ac": "D3ZML2", "gene_name": "Brsk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] } ] }, { "uniprot_ac": "D3ZQN8", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZQN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZQN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQN8" } ] } ] }, { "uniprot_ac": "D3ZRJ7", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZRJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZRJ7" } ] } ] }, { "uniprot_ac": "D3ZSB7", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSB7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSB7" } ] } ] }, { "uniprot_ac": "D3ZSY9", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZSY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSY9" } ] } ] }, { "uniprot_ac": "D3ZSZ3", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSZ3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "D3ZSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSZ3" } ] } ] }, { "uniprot_ac": "D3ZTD1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZTD1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZTD1" } ] } ] }, { "uniprot_ac": "D3ZXB1", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZXB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZXB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZXB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZXB1" } ] } ] }, { "uniprot_ac": "D3ZY07", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZY07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZY07" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "D3ZY07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZY07" } ] } ] }, { "uniprot_ac": "D3ZZK7", "gene_name": "Myo3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZK7" } ] } ] }, { "uniprot_ac": "D4A229", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A229" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "D4A229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A229" } ] } ] }, { "uniprot_ac": "D4A280", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A280" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A280" } ] } ] }, { "uniprot_ac": "D4A355", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A355" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A355" } ] } ] }, { "uniprot_ac": "D4A3D9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3D9" } ] } ] }, { "uniprot_ac": "D4A3H8", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3H8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3H8" } ] } ] }, { "uniprot_ac": "D4A454", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A454" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D4A454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A454" } ] } ] }, { "uniprot_ac": "D4A6T6", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A6T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A6T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T6" } ] } ] }, { "uniprot_ac": "D4A6T9", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A6T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A6T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T9" } ] } ] }, { "uniprot_ac": "D4A7V9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7V9" } ] } ] }, { "uniprot_ac": "D4A949", "gene_name": "Smokl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A949" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A949" } ] } ] }, { "uniprot_ac": "D4A9H8", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A9H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A9H8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A9H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A9H8" } ] } ] }, { "uniprot_ac": "D4ACL8", "gene_name": "Atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4ACL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACL8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4ACL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACL8" } ] } ] }, { "uniprot_ac": "D4AD76", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AD76" } ] } ] }, { "uniprot_ac": "D4AE24", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AE24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AE24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE24" } ] } ] }, { "uniprot_ac": "D4AE59", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AE59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AE59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE59" } ] } ] }, { "uniprot_ac": "E9PSK5", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSK5" } ] } ] }, { "uniprot_ac": "E9PSL7", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSL7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSL7" } ] } ] }, { "uniprot_ac": "E9PSM2", "gene_name": "LOC301165", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSM2" } ] } ] }, { "uniprot_ac": "E9PTG8", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTG8" } ] } ] }, { "uniprot_ac": "E9Q3S4", "gene_name": "Map3k19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9Q3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9Q3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q3S4" } ] } ] }, { "uniprot_ac": "F1LNJ1", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LNJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LNJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ1" } ] } ] }, { "uniprot_ac": "F1LNN8", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNN8" } ] } ] }, { "uniprot_ac": "F1LP90", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP90" } ] } ] }, { "uniprot_ac": "F1LRA7", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LRA7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1LRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LRA7" } ] } ] }, { "uniprot_ac": "F1LTP9", "gene_name": "LOC120093110", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTP9" } ] } ] }, { "uniprot_ac": "F1LUY7", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LUY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUY7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1LUY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUY7" } ] } ] }, { "uniprot_ac": "F1LWF2", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWF2" } ] } ] }, { "uniprot_ac": "F1LWJ6", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWJ6" } ] } ] }, { "uniprot_ac": "F1LXF1", "gene_name": "Bcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LXF1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LXF1" } ] } ] }, { "uniprot_ac": "F1LYY7", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LYY7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1LYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LYY7" } ] } ] }, { "uniprot_ac": "F1M0Z1", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M0Z1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M0Z1" } ] } ] }, { "uniprot_ac": "F1M419", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M419" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M419" } ] } ] }, { "uniprot_ac": "F1M7G0", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7G0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M7G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7G0" } ] } ] }, { "uniprot_ac": "F1M7N7", "gene_name": "Rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7N7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M7N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7N7" } ] } ] }, { "uniprot_ac": "F1M7Y5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7Y5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1M7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7Y5" } ] } ] }, { "uniprot_ac": "F1M9D0", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9D0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1M9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9D0" } ] } ] }, { "uniprot_ac": "F7FMK8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F7FMK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7FMK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F7FMK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7FMK8" } ] } ] }, { "uniprot_ac": "G3V783", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] } ] }, { "uniprot_ac": "J3KMT3", "gene_name": "Gm6882", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "J3KMT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3KMT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "J3KMT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3KMT3" } ] } ] }, { "uniprot_ac": "J3QK59", "gene_name": "Gm6176", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "J3QK59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3QK59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "J3QK59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3QK59" } ] } ] }, { "uniprot_ac": "M0R777", "gene_name": "LOC102551633", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0R777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R777" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0R777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R777" } ] } ] }, { "uniprot_ac": "M0R7E7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0R7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R7E7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "M0R7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R7E7" } ] } ] }, { "uniprot_ac": "M0RBT0", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RBT0" } ] } ] }, { "uniprot_ac": "M0RD40", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD40" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD40" } ] } ] }, { "uniprot_ac": "M0RD88", "gene_name": "Smok2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD88" } ] } ] }, { "uniprot_ac": "M0RDM0", "gene_name": "LOC103689976", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RDM0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RDM0" } ] } ] }, { "uniprot_ac": "M9NGC6", "gene_name": "Srpk79D", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9NGC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9NGC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9NGC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9NGC6" } ] } ] }, { "uniprot_ac": "M9PGC5", "gene_name": "Wnk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PGC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PGC5" } ] } ] }, { "uniprot_ac": "M9PI41", "gene_name": "sti", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI41" } ] } ] }, { "uniprot_ac": "O00141", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00141" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00141" } ] } ] }, { "uniprot_ac": "O00311", "gene_name": "CDC7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00311", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00311" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00311", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00311" } ] } ] }, { "uniprot_ac": "O00444", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00444" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O00444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00444" } ] } ] }, { "uniprot_ac": "O00506", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00506" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00506" } ] } ] }, { "uniprot_ac": "O08605", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08605" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08605" } ] } ] }, { "uniprot_ac": "O08648", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08648" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O08648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08648" } ] } ] }, { "uniprot_ac": "O08678", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] } ] }, { "uniprot_ac": "O08679", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] } ] }, { "uniprot_ac": "O08815", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08815" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08815" } ] } ] }, { "uniprot_ac": "O08874", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08874" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "O08874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08874" } ] } ] }, { "uniprot_ac": "O08875", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08875" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08875" } ] } ] }, { "uniprot_ac": "O08901", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08901" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08901" } ] } ] }, { "uniprot_ac": "O08911", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08911" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O08911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08911" } ] } ] }, { "uniprot_ac": "O09110", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O09110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09110" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O09110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09110" } ] } ] }, { "uniprot_ac": "O14578", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14578" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14578" } ] } ] }, { "uniprot_ac": "O14730", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14730" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14730" } ] } ] }, { "uniprot_ac": "O14733", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14733" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O14733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14733" } ] } ] }, { "uniprot_ac": "O14757", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14757" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14757" } ] } ] }, { "uniprot_ac": "O14874", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] } ] }, { "uniprot_ac": "O14920", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] } ] }, { "uniprot_ac": "O14936", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14936" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14936" } ] } ] }, { "uniprot_ac": "O14965", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14965" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14965" } ] } ] }, { "uniprot_ac": "O14976", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14976" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14976" } ] } ] }, { "uniprot_ac": "O15021", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15021" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15021" } ] } ] }, { "uniprot_ac": "O15075", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15075", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15075" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15075", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15075" } ] } ] }, { "uniprot_ac": "O15264", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15264" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O15264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15264" } ] } ] }, { "uniprot_ac": "O15530", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15530" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15530" } ] } ] }, { "uniprot_ac": "O35099", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35099" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O35099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35099" } ] } ] }, { "uniprot_ac": "O35280", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35280" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O35280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35280" } ] } ] }, { "uniprot_ac": "O35491", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35491" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35491" } ] } ] }, { "uniprot_ac": "O35492", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35492" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35492" } ] } ] }, { "uniprot_ac": "O35493", "gene_name": "Clk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35493" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35493" } ] } ] }, { "uniprot_ac": "O35495", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35495" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35495" } ] } ] }, { "uniprot_ac": "O35831", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35831" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35831" } ] } ] }, { "uniprot_ac": "O35832", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35832" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35832" } ] } ] }, { "uniprot_ac": "O35942", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35942" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O35942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35942" } ] } ] }, { "uniprot_ac": "O43283", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43283" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O43283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43283" } ] } ] }, { "uniprot_ac": "O43293", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43293" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43293" } ] } ] }, { "uniprot_ac": "O43318", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43318" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O43318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43318" } ] } ] }, { "uniprot_ac": "O43353", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] } ] }, { "uniprot_ac": "O43683", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43683" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43683" } ] } ] }, { "uniprot_ac": "O43781", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43781" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O43781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43781" } ] } ] }, { "uniprot_ac": "O43930", "gene_name": "PRKY", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43930" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43930" } ] } ] }, { "uniprot_ac": "O54748", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54748" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54748" } ] } ] }, { "uniprot_ac": "O54781", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54781" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54781" } ] } ] }, { "uniprot_ac": "O54784", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54784" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54784" } ] } ] }, { "uniprot_ac": "O54785", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54785" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54785" } ] } ] }, { "uniprot_ac": "O54833", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54833" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54833" } ] } ] }, { "uniprot_ac": "O54863", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54863" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54863" } ] } ] }, { "uniprot_ac": "O54874", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54874" } ] } ] }, { "uniprot_ac": "O54949", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54949" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O54949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54949" } ] } ] }, { "uniprot_ac": "O54967", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] } ] }, { "uniprot_ac": "O54988", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54988", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54988" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54988", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54988" } ] } ] }, { "uniprot_ac": "O54992", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54992" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54992" } ] } ] }, { "uniprot_ac": "O55028", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] } ] }, { "uniprot_ac": "O55047", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55047" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55047" } ] } ] }, { "uniprot_ac": "O55098", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] } ] }, { "uniprot_ac": "O55099", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55099" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55099" } ] } ] }, { "uniprot_ac": "O55173", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55173" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55173" } ] } ] }, { "uniprot_ac": "O55222", "gene_name": "Ilk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55222" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55222" } ] } ] }, { "uniprot_ac": "O60229", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60229" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60229" } ] } ] }, { "uniprot_ac": "O60285", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60285" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60285" } ] } ] }, { "uniprot_ac": "O60307", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60307" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60307" } ] } ] }, { "uniprot_ac": "O60566", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60566" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60566" } ] } ] }, { "uniprot_ac": "O61122", "gene_name": "svkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61122" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61122" } ] } ] }, { "uniprot_ac": "O61125", "gene_name": "krsA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61125" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61125" } ] } ] }, { "uniprot_ac": "O61267", "gene_name": "lok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61443" } ] } ] }, { "uniprot_ac": "O61444", "gene_name": "Mkk4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61444" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O61444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61444" } ] } ] }, { "uniprot_ac": "O61661", "gene_name": "grp", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61661" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61661" } ] } ] }, { "uniprot_ac": "O62602", "gene_name": "lic", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O62602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62602" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O62602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62602" } ] } ] }, { "uniprot_ac": "O62618", "gene_name": "p38a", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62618" } ] } ] }, { "uniprot_ac": "O70126", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70126" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70126" } ] } ] }, { "uniprot_ac": "O70146", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70146" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O70146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70146" } ] } ] }, { "uniprot_ac": "O70150", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70150" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "O70150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70150" } ] } ] }, { "uniprot_ac": "O70405", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70405" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70405" } ] } ] }, { "uniprot_ac": "O70444", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70444" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70444" } ] } ] }, { "uniprot_ac": "O70551", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70551" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70551" } ] } ] }, { "uniprot_ac": "O70589", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70589" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70589" } ] } ] }, { "uniprot_ac": "O75116", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75116" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75116" } ] } ] }, { "uniprot_ac": "O75385", "gene_name": "ULK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75385" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75385" } ] } ] }, { "uniprot_ac": "O75460", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] } ] }, { "uniprot_ac": "O75582", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75582", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75582" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75582", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75582" } ] } ] }, { "uniprot_ac": "O75676", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75676" } ] } ] }, { "uniprot_ac": "O75716", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] } ] }, { "uniprot_ac": "O75914", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75914" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75914" } ] } ] }, { "uniprot_ac": "O75962", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75962" } ] } ] }, { "uniprot_ac": "O76039", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O76039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76039" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O76039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76039" } ] } ] }, { "uniprot_ac": "O76324", "gene_name": "dco", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76324" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76324" } ] } ] }, { "uniprot_ac": "O88351", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] } ] }, { "uniprot_ac": "O88445", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88445" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88445" } ] } ] }, { "uniprot_ac": "O88506", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88506" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88506" } ] } ] }, { "uniprot_ac": "O88643", "gene_name": "Pak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88643" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88643" } ] } ] }, { "uniprot_ac": "O88664", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88664" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88664" } ] } ] }, { "uniprot_ac": "O88697", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] } ] }, { "uniprot_ac": "O88764", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88764" } ] } ] }, { "uniprot_ac": "O88831", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88831" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "O88831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88831" } ] } ] }, { "uniprot_ac": "O88850", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88850" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88850" } ] } ] }, { "uniprot_ac": "O88866", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88866" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88866" } ] } ] }, { "uniprot_ac": "O88904", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88904", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88904" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88904", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88904" } ] } ] }, { "uniprot_ac": "O94768", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94768" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O94768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94768" } ] } ] }, { "uniprot_ac": "O94804", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94804" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O94804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94804" } ] } ] }, { "uniprot_ac": "O94806", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94806" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "O94806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94806" } ] } ] }, { "uniprot_ac": "O94921", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94921" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O94921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94921" } ] } ] }, { "uniprot_ac": "O95382", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95382" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O95382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95382" } ] } ] }, { "uniprot_ac": "O95747", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95747" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95747" } ] } ] }, { "uniprot_ac": "O95819", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95819" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95819" } ] } ] }, { "uniprot_ac": "O95835", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95835" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95835" } ] } ] }, { "uniprot_ac": "O96013", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O96013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96013" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O96013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96013" } ] } ] }, { "uniprot_ac": "O96017", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O96017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96017" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O96017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96017" } ] } ] }, { "uniprot_ac": "O97143", "gene_name": "SAK", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97143" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97143" } ] } ] }, { "uniprot_ac": "P00536", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00536" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00536" } ] } ] }, { "uniprot_ac": "P00539", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00539" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00539" } ] } ] }, { "uniprot_ac": "P00540", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00540" } ] } ] }, { "uniprot_ac": "P00546", "gene_name": "CDC28", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00546" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P00546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00546" } ] } ] }, { "uniprot_ac": "P04049", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04049" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04049" } ] } ] }, { "uniprot_ac": "P04627", "gene_name": "Araf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P04627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04627" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P04627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04627" } ] } ] }, { "uniprot_ac": "P05129", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05129" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05129" } ] } ] }, { "uniprot_ac": "P05130", "gene_name": "Pkc53E", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05130" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05130" } ] } ] }, { "uniprot_ac": "P05132", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05132" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05132" } ] } ] }, { "uniprot_ac": "P05696", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05696" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05696" } ] } ] }, { "uniprot_ac": "P05771", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05771" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05771" } ] } ] }, { "uniprot_ac": "P05986", "gene_name": "TPK3", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05986" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05986" } ] } ] }, { "uniprot_ac": "P06243", "gene_name": "CDC7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06243" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06243" } ] } ] }, { "uniprot_ac": "P06244", "gene_name": "TPK1", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06244" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P06244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06244" } ] } ] }, { "uniprot_ac": "P06245", "gene_name": "TPK2", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06245" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P06245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06245" } ] } ] }, { "uniprot_ac": "P06493", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] } ] }, { "uniprot_ac": "P06782", "gene_name": "SNF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06782" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06782" } ] } ] }, { "uniprot_ac": "P06784", "gene_name": "STE7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06784" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P06784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06784" } ] } ] }, { "uniprot_ac": "P06803", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06803" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06803" } ] } ] }, { "uniprot_ac": "P07934", "gene_name": "Phkg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] } ] }, { "uniprot_ac": "P08018", "gene_name": "PBS2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08018" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P08018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08018" } ] } ] }, { "uniprot_ac": "P08181", "gene_name": "CkIIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08181" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08181" } ] } ] }, { "uniprot_ac": "P08413", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08413" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P08413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08413" } ] } ] }, { "uniprot_ac": "P08414", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08414" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P08414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08414" } ] } ] }, { "uniprot_ac": "P08458", "gene_name": "SPS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08458" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08458" } ] } ] }, { "uniprot_ac": "P09215", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] } ] }, { "uniprot_ac": "P09216", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09216" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09216" } ] } ] }, { "uniprot_ac": "P09217", "gene_name": "Prkcz", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09217" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09217" } ] } ] }, { "uniprot_ac": "P0C0R5", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C0R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C0R5" } ] } ] }, { "uniprot_ac": "P0C1X8", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C1X8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C1X8" } ] } ] }, { "uniprot_ac": "P0C263", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C263" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C263" } ] } ] }, { "uniprot_ac": "P0C264", "gene_name": "SBK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C264" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C264" } ] } ] }, { "uniprot_ac": "P0C5K0", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K0" } ] } ] }, { "uniprot_ac": "P0C5K1", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K1" } ] } ] }, { "uniprot_ac": "P0C605", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C605" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P0C605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C605" } ] } ] }, { "uniprot_ac": "P0C865", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C865", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C865" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P0C865", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C865" } ] } ] }, { "uniprot_ac": "P0C8E4", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C8E4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P0C8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C8E4" } ] } ] }, { "uniprot_ac": "P0CD62", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0CD62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CD62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0CD62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CD62" } ] } ] }, { "uniprot_ac": "P10398", "gene_name": "ARAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P10398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10398" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10398" } ] } ] }, { "uniprot_ac": "P10676", "gene_name": "ninaC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10676" } ] } ] }, { "uniprot_ac": "P11274", "gene_name": "BCR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11274" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11274" } ] } ] }, { "uniprot_ac": "P11275", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11275" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11275" } ] } ] }, { "uniprot_ac": "P11309", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11309" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11309" } ] } ] }, { "uniprot_ac": "P11345", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11345" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11345" } ] } ] }, { "uniprot_ac": "P11346", "gene_name": "Raf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11346" } ] } ] }, { "uniprot_ac": "P11440", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] } ] }, { "uniprot_ac": "P11730", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11730" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11730" } ] } ] }, { "uniprot_ac": "P11792", "gene_name": "SCH9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11792" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11792" } ] } ] }, { "uniprot_ac": "P11798", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11798" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11798" } ] } ] }, { "uniprot_ac": "P11801", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11801" } ] } ] }, { "uniprot_ac": "P11802", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11802" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P11802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11802" } ] } ] }, { "uniprot_ac": "P11980", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] } ] }, { "uniprot_ac": "P12370", "gene_name": "Pka-C1", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12370" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12370" } ] } ] }, { "uniprot_ac": "P12688", "gene_name": "YPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P12688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12688" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P12688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12688" } ] } ] }, { "uniprot_ac": "P13185", "gene_name": "KIN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P13185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13185" } ] } ] }, { "uniprot_ac": "P13186", "gene_name": "KIN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13186" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P13186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13186" } ] } ] }, { "uniprot_ac": "P13234", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13234" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P13234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13234" } ] } ] }, { "uniprot_ac": "P13286", "gene_name": "Phkg1", "activity": [ { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] } ] }, { "uniprot_ac": "P13677", "gene_name": "inaC", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13677" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13677" } ] } ] }, { "uniprot_ac": "P13678", "gene_name": "Pkc98E", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13678" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13678" } ] } ] }, { "uniprot_ac": "P14056", "gene_name": "Araf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14056" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P14056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14056" } ] } ] }, { "uniprot_ac": "P14618", "gene_name": "PKM", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] } ] }, { "uniprot_ac": "P14680", "gene_name": "YAK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14680" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14680" } ] } ] }, { "uniprot_ac": "P14681", "gene_name": "KSS1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14681" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P14681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14681" } ] } ] }, { "uniprot_ac": "P15056", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15056" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15056" } ] } ] }, { "uniprot_ac": "P15442", "gene_name": "GCN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15442" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15442" } ] } ] }, { "uniprot_ac": "P15790", "gene_name": "CKA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15790" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15790" } ] } ] }, { "uniprot_ac": "P15791", "gene_name": "Camk2d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15791" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P15791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15791" } ] } ] }, { "uniprot_ac": "P16054", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16054" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P16054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16054" } ] } ] }, { "uniprot_ac": "P16892", "gene_name": "FUS3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16892" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P16892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16892" } ] } ] }, { "uniprot_ac": "P16911", "gene_name": "Pka-C2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] } ] }, { "uniprot_ac": "P16912", "gene_name": "Pka-C3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16912" } ] } ] }, { "uniprot_ac": "P17157", "gene_name": "PHO85", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17157" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P17157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17157" } ] } ] }, { "uniprot_ac": "P17252", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17252" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P17252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17252" } ] } ] }, { "uniprot_ac": "P17612", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17612" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P17612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17612" } ] } ] }, { "uniprot_ac": "P18265", "gene_name": "Gsk3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] } ] }, { "uniprot_ac": "P18266", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] } ] }, { "uniprot_ac": "P18431", "gene_name": "sgg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18431" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18431" } ] } ] }, { "uniprot_ac": "P18653", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18653", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18653" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18653", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18653" } ] } ] }, { "uniprot_ac": "P18654", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18654" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18654" } ] } ] }, { "uniprot_ac": "P18961", "gene_name": "YPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18961", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18961" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18961", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18961" } ] } ] }, { "uniprot_ac": "P19139", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19139" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19139" } ] } ] }, { "uniprot_ac": "P19454", "gene_name": "CKA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19454" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19454" } ] } ] }, { "uniprot_ac": "P19525", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] } ] }, { "uniprot_ac": "P19784", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19784" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19784" } ] } ] }, { "uniprot_ac": "P20444", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20444" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P20444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20444" } ] } ] }, { "uniprot_ac": "P20793", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20793" } ] } ] }, { "uniprot_ac": "P20794", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20794" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20794" } ] } ] }, { "uniprot_ac": "P21127", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21127" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P21127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21127" } ] } ] }, { "uniprot_ac": "P21675", "gene_name": "TAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] } ] }, { "uniprot_ac": "P21708", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21708" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P21708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21708" } ] } ] }, { "uniprot_ac": "P21965", "gene_name": "MCK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21965" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P21965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21965" } ] } ] }, { "uniprot_ac": "P22204", "gene_name": "DBF2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22204" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22204" } ] } ] }, { "uniprot_ac": "P22209", "gene_name": "KIN3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22209" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22209" } ] } ] }, { "uniprot_ac": "P22211", "gene_name": "NPR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22211", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22211" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22211", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22211" } ] } ] }, { "uniprot_ac": "P22216", "gene_name": "RAD53", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22216" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P22216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22216" } ] } ] }, { "uniprot_ac": "P22219", "gene_name": "VPS15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22219", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22219" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22219", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22219" } ] } ] }, { "uniprot_ac": "P22517", "gene_name": "CMK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22517" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P22517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22517" } ] } ] }, { "uniprot_ac": "P22518", "gene_name": "Clk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22518" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P22518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22518" } ] } ] }, { "uniprot_ac": "P22612", "gene_name": "PRKACG", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22612" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P22612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22612" } ] } ] }, { "uniprot_ac": "P22694", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22694" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P22694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22694" } ] } ] }, { "uniprot_ac": "P23291", "gene_name": "YCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23291", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23291" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23291", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23291" } ] } ] }, { "uniprot_ac": "P23292", "gene_name": "YCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23292" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23292" } ] } ] }, { "uniprot_ac": "P23293", "gene_name": "SGV1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] } ] }, { "uniprot_ac": "P23298", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23298" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P23298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23298" } ] } ] }, { "uniprot_ac": "P23443", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23443" } ] } ] }, { "uniprot_ac": "P23561", "gene_name": "STE11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23561" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P23561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23561" } ] } ] }, { "uniprot_ac": "P23572", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] } ] }, { "uniprot_ac": "P23573", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] } ] }, { "uniprot_ac": "P23647", "gene_name": "fu", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23647" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23647" } ] } ] }, { "uniprot_ac": "P24583", "gene_name": "PKC1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24583" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P24583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24583" } ] } ] }, { "uniprot_ac": "P24719", "gene_name": "MEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24719" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P24719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24719" } ] } ] }, { "uniprot_ac": "P24723", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24723" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P24723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24723" } ] } ] }, { "uniprot_ac": "P24788", "gene_name": "Cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24788" } ] } ] }, { "uniprot_ac": "P24941", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24941" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P24941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24941" } ] } ] }, { "uniprot_ac": "P25333", "gene_name": "SAT4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25333" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25333" } ] } ] }, { "uniprot_ac": "P25341", "gene_name": "KIN82", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25341", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25341" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25341", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25341" } ] } ] }, { "uniprot_ac": "P25389", "gene_name": "KCC4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25389" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25389" } ] } ] }, { "uniprot_ac": "P25390", "gene_name": "SSK22", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25390", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25390" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25390", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25390" } ] } ] }, { "uniprot_ac": "P26794", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P26794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26794" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P26794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26794" } ] } ] }, { "uniprot_ac": "P27361", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27361" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P27361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27361" } ] } ] }, { "uniprot_ac": "P27448", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27448" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P27448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27448" } ] } ] }, { "uniprot_ac": "P27466", "gene_name": "CMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27466" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P27466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27466" } ] } ] }, { "uniprot_ac": "P27636", "gene_name": "CDC15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27636" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P27636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27636" } ] } ] }, { "uniprot_ac": "P27704", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27704" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P27704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27704" } ] } ] }, { "uniprot_ac": "P27791", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27791" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P27791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27791" } ] } ] }, { "uniprot_ac": "P28028", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28028" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28028" } ] } ] }, { "uniprot_ac": "P28178", "gene_name": "pkgB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28178" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28178" } ] } ] }, { "uniprot_ac": "P28482", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28482" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P28482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28482" } ] } ] }, { "uniprot_ac": "P28652", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28652" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P28652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28652" } ] } ] }, { "uniprot_ac": "P28708", "gene_name": "PRR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28708" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28708" } ] } ] }, { "uniprot_ac": "P28867", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] }, { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] } ] }, { "uniprot_ac": "P29295", "gene_name": "HRR25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P29295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29295" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P29295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29295" } ] } ] }, { "uniprot_ac": "P30285", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P30285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30285" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P30285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30285" } ] } ] }, { "uniprot_ac": "P31152", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31152" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P31152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31152" } ] } ] }, { "uniprot_ac": "P31374", "gene_name": "PSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31374" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31374" } ] } ] }, { "uniprot_ac": "P31749", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31749" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31749" } ] } ] }, { "uniprot_ac": "P31750", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31750" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31750" } ] } ] }, { "uniprot_ac": "P31751", "gene_name": "AKT2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31751" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31751" } ] } ] }, { "uniprot_ac": "P31938", "gene_name": "Map2k1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31938" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P31938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31938" } ] } ] }, { "uniprot_ac": "P32328", "gene_name": "DBF20", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32328" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32328" } ] } ] }, { "uniprot_ac": "P32350", "gene_name": "KNS1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32350" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P32350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32350" } ] } ] }, { "uniprot_ac": "P32361", "gene_name": "IRE1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32361" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "P32361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32361" } ] } ] }, { "uniprot_ac": "P32485", "gene_name": "HOG1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32485" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P32485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32485" } ] } ] }, { "uniprot_ac": "P32490", "gene_name": "MKK1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32490" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P32490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32490" } ] } ] }, { "uniprot_ac": "P32491", "gene_name": "MKK2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32491" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P32491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32491" } ] } ] }, { "uniprot_ac": "P32562", "gene_name": "CDC5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32562" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P32562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32562" } ] } ] }, { "uniprot_ac": "P32581", "gene_name": "IME2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32581" } ] } ] }, { "uniprot_ac": "P32600", "gene_name": "TOR2", "activity": [ { "ec_number": "2.7.1.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.1.67", "activity": "", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] } ] }, { "uniprot_ac": "P32789", "gene_name": "ALK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32789", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32789" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32789", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32789" } ] } ] }, { "uniprot_ac": "P32801", "gene_name": "ELM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32801" } ] } ] }, { "uniprot_ac": "P32944", "gene_name": "SWE1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32944" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32944" } ] } ] }, { "uniprot_ac": "P33076", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] } ] }, { "uniprot_ac": "P33981", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P33981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33981" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P33981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33981" } ] } ] }, { "uniprot_ac": "P34099", "gene_name": "pkaC", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34099" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P34099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34099" } ] } ] }, { "uniprot_ac": "P34100", "gene_name": "pkaD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34100" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34100" } ] } ] }, { "uniprot_ac": "P34101", "gene_name": "fhkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34101" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34101" } ] } ] }, { "uniprot_ac": "P34102", "gene_name": "pkgC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34102" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34102" } ] } ] }, { "uniprot_ac": "P34103", "gene_name": "pkgD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34103" } ] } ] }, { "uniprot_ac": "P34112", "gene_name": "cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] } ] }, { "uniprot_ac": "P34117", "gene_name": "cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34117" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P34117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34117" } ] } ] }, { "uniprot_ac": "P34244", "gene_name": "HSL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34244" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34244" } ] } ] }, { "uniprot_ac": "P35169", "gene_name": "TOR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35169", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35169" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35169", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35169" } ] } ] }, { "uniprot_ac": "P35426", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35426", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35426" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P35426", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35426" } ] } ] }, { "uniprot_ac": "P35465", "gene_name": "Pak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35465" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35465" } ] } ] }, { "uniprot_ac": "P35761", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35761" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P35761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35761" } ] } ] }, { "uniprot_ac": "P36002", "gene_name": "PTK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36002" } ] } ] }, { "uniprot_ac": "P36003", "gene_name": "NNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36003" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36003" } ] } ] }, { "uniprot_ac": "P36004", "gene_name": "KKQ8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36004" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36004" } ] } ] }, { "uniprot_ac": "P36005", "gene_name": "KDX1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36005" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36005" } ] } ] }, { "uniprot_ac": "P36506", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36506" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P36506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36506" } ] } ] }, { "uniprot_ac": "P36507", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36507" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P36507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36507" } ] } ] }, { "uniprot_ac": "P38070", "gene_name": "YPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38070" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38070" } ] } ] }, { "uniprot_ac": "P38080", "gene_name": "AKL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38080" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38080" } ] } ] }, { "uniprot_ac": "P38110", "gene_name": "TEL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38110" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38110" } ] } ] }, { "uniprot_ac": "P38111", "gene_name": "MEC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38111" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38111" } ] } ] }, { "uniprot_ac": "P38147", "gene_name": "CHK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38147" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38147" } ] } ] }, { "uniprot_ac": "P38615", "gene_name": "RIM11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38615" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38615" } ] } ] }, { "uniprot_ac": "P38622", "gene_name": "RCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38622" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38622" } ] } ] }, { "uniprot_ac": "P38623", "gene_name": "RCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38623" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38623" } ] } ] }, { "uniprot_ac": "P38691", "gene_name": "KSP1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38691" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38691" } ] } ] }, { "uniprot_ac": "P38692", "gene_name": "KIC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38692" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38692" } ] } ] }, { "uniprot_ac": "P38970", "gene_name": "HAL5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38970" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38970" } ] } ] }, { "uniprot_ac": "P38990", "gene_name": "SAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38990" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38990" } ] } ] }, { "uniprot_ac": "P38991", "gene_name": "IPL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38991" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38991" } ] } ] }, { "uniprot_ac": "P39009", "gene_name": "DUN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39009" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P39009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39009" } ] } ] }, { "uniprot_ac": "P39073", "gene_name": "SSN3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] } ] }, { "uniprot_ac": "P39951", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] } ] }, { "uniprot_ac": "P39962", "gene_name": "YCK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P39962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39962" } ] } ] }, { "uniprot_ac": "P40160", "gene_name": "RIO2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40160" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P40160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40160" } ] } ] }, { "uniprot_ac": "P40417", "gene_name": "rl", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40417" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40417" } ] } ] }, { "uniprot_ac": "P40494", "gene_name": "PRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40494" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P40494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40494" } ] } ] }, { "uniprot_ac": "P41279", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] } ] }, { "uniprot_ac": "P41695", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41695" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P41695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41695" } ] } ] }, { "uniprot_ac": "P41743", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41743" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P41743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41743" } ] } ] }, { "uniprot_ac": "P41808", "gene_name": "SMK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41808" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P41808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41808" } ] } ] }, { "uniprot_ac": "P42336", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] } ] }, { "uniprot_ac": "P42337", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] } ] }, { "uniprot_ac": "P42338", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] } ] }, { "uniprot_ac": "P42345", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42345" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P42345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42345" } ] } ] }, { "uniprot_ac": "P42346", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P42346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42346" } ] } ] }, { "uniprot_ac": "P42525", "gene_name": "erkA", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42525" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P42525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42525" } ] } ] }, { "uniprot_ac": "P43565", "gene_name": "RIM15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43565" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43565" } ] } ] }, { "uniprot_ac": "P43568", "gene_name": "CAK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43568" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P43568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43568" } ] } ] }, { "uniprot_ac": "P43633", "gene_name": "ALK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43633" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43633" } ] } ] }, { "uniprot_ac": "P43637", "gene_name": "TOS3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43637" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43637" } ] } ] }, { "uniprot_ac": "P45983", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45983" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P45983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45983" } ] } ] }, { "uniprot_ac": "P45984", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45984" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P45984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45984" } ] } ] }, { "uniprot_ac": "P45985", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45985" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P45985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45985" } ] } ] }, { "uniprot_ac": "P46734", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P46734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46734" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P46734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46734" } ] } ] }, { "uniprot_ac": "P46892", "gene_name": "Cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P46892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46892" } ] } ] }, { "uniprot_ac": "P47042", "gene_name": "IKS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47042" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47042" } ] } ] }, { "uniprot_ac": "P47116", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47116" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47116" } ] } ] }, { "uniprot_ac": "P47196", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47196" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47196" } ] } ] }, { "uniprot_ac": "P47197", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47197" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47197" } ] } ] }, { "uniprot_ac": "P47809", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47809" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P47809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47809" } ] } ] }, { "uniprot_ac": "P47811", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47811" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P47811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47811" } ] } ] }, { "uniprot_ac": "P48562", "gene_name": "CLA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48562" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48562" } ] } ] }, { "uniprot_ac": "P48609", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48609" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48609" } ] } ] }, { "uniprot_ac": "P48729", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48729" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48729" } ] } ] }, { "uniprot_ac": "P48730", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] } ] }, { "uniprot_ac": "P48736", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] } ] }, { "uniprot_ac": "P49025", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49025" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49025" } ] } ] }, { "uniprot_ac": "P49071", "gene_name": "MAPk-Ak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49071" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49071" } ] } ] }, { "uniprot_ac": "P49137", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49137" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49137" } ] } ] }, { "uniprot_ac": "P49138", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49138" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49138" } ] } ] }, { "uniprot_ac": "P49185", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49185" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49185" } ] } ] }, { "uniprot_ac": "P49186", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49186" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49186" } ] } ] }, { "uniprot_ac": "P49187", "gene_name": "Mapk10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49187" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49187" } ] } ] }, { "uniprot_ac": "P49336", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] } ] }, { "uniprot_ac": "P49615", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49615" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49615" } ] } ] }, { "uniprot_ac": "P49657", "gene_name": "mnb", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49657" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49657" } ] } ] }, { "uniprot_ac": "P49674", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49674" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49674" } ] } ] }, { "uniprot_ac": "P49759", "gene_name": "CLK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49759" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49759" } ] } ] }, { "uniprot_ac": "P49760", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49760" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49760" } ] } ] }, { "uniprot_ac": "P49761", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49761" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49761" } ] } ] }, { "uniprot_ac": "P49762", "gene_name": "Doa", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] } ] }, { "uniprot_ac": "P49840", "gene_name": "GSK3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] } ] }, { "uniprot_ac": "P49841", "gene_name": "GSK3B", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] } ] }, { "uniprot_ac": "P50613", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] } ] }, { "uniprot_ac": "P50750", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] } ] }, { "uniprot_ac": "P50873", "gene_name": "MRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50873" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P50873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50873" } ] } ] }, { "uniprot_ac": "P51123", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51123" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51123" } ] } ] }, { "uniprot_ac": "P51617", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51617" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51617" } ] } ] }, { "uniprot_ac": "P51812", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51812", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51812" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51812", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51812" } ] } ] }, { "uniprot_ac": "P51817", "gene_name": "PRKX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51817" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51817" } ] } ] }, { "uniprot_ac": "P51952", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] } ] }, { "uniprot_ac": "P51954", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51954" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51954" } ] } ] }, { "uniprot_ac": "P51955", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51955" } ] } ] }, { "uniprot_ac": "P51956", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51956" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51956" } ] } ] }, { "uniprot_ac": "P51957", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51957" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51957" } ] } ] }, { "uniprot_ac": "P52304", "gene_name": "polo", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52304" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52304" } ] } ] }, { "uniprot_ac": "P52480", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] } ] }, { "uniprot_ac": "P52564", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52564" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P52564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52564" } ] } ] }, { "uniprot_ac": "P53104", "gene_name": "ATG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53104" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53104" } ] } ] }, { "uniprot_ac": "P53233", "gene_name": "FMP48", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53233" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53233" } ] } ] }, { "uniprot_ac": "P53323", "gene_name": "BUD32", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53323" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "P53323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53323" } ] } ] }, { "uniprot_ac": "P53349", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53349" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P53349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53349" } ] } ] }, { "uniprot_ac": "P53350", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53350" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P53350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53350" } ] } ] }, { "uniprot_ac": "P53351", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53351" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P53351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53351" } ] } ] }, { "uniprot_ac": "P53355", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53355" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53355" } ] } ] }, { "uniprot_ac": "P53599", "gene_name": "SSK2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53599" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P53599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53599" } ] } ] }, { "uniprot_ac": "P53667", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53667" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53667" } ] } ] }, { "uniprot_ac": "P53668", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53668", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53668" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53668", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53668" } ] } ] }, { "uniprot_ac": "P53669", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53669", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53669" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53669", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53669" } ] } ] }, { "uniprot_ac": "P53670", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53670" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53670" } ] } ] }, { "uniprot_ac": "P53671", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53671", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53671" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53671", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53671" } ] } ] }, { "uniprot_ac": "P53739", "gene_name": "FPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53739" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53739" } ] } ] }, { "uniprot_ac": "P53778", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53778" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P53778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53778" } ] } ] }, { "uniprot_ac": "P53779", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53779" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P53779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53779" } ] } ] }, { "uniprot_ac": "P53894", "gene_name": "CBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53894", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53894" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53894", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53894" } ] } ] }, { "uniprot_ac": "P53974", "gene_name": "ARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53974" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53974" } ] } ] }, { "uniprot_ac": "P54199", "gene_name": "MPS1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54199" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P54199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54199" } ] } ] }, { "uniprot_ac": "P54265", "gene_name": "Dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54265" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54265" } ] } ] }, { "uniprot_ac": "P54360", "gene_name": "fj", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54360" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54360" } ] } ] }, { "uniprot_ac": "P54367", "gene_name": "CkIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54367" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54367" } ] } ] }, { "uniprot_ac": "P54644", "gene_name": "pkbA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54644" } ] } ] }, { "uniprot_ac": "P54645", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] } ] }, { "uniprot_ac": "P54646", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] } ] }, { "uniprot_ac": "P54685", "gene_name": "cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] } ] }, { "uniprot_ac": "P57058", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57058" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57058" } ] } ] }, { "uniprot_ac": "P57059", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57059" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57059" } ] } ] }, { "uniprot_ac": "P57078", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57078" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57078" } ] } ] }, { "uniprot_ac": "P57760", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] } ] }, { "uniprot_ac": "P58750", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P58750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58750" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P58750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58750" } ] } ] }, { "uniprot_ac": "P58801", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] } ] }, { "uniprot_ac": "P59241", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P59241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P59241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59241" } ] } ] }, { "uniprot_ac": "P59895", "gene_name": "Nek6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P59895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59895" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "P59895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59895" } ] } ] }, { "uniprot_ac": "P62491", "gene_name": "RAB11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P62491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62491" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P62491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62491" } ] } ] }, { "uniprot_ac": "P63085", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63085" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P63085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63085" } ] } ] }, { "uniprot_ac": "P63086", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63086" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P63086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63086" } ] } ] }, { "uniprot_ac": "P63318", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63318" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P63318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63318" } ] } ] }, { "uniprot_ac": "P63319", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63319" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P63319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63319" } ] } ] }, { "uniprot_ac": "P67999", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P67999", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67999" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67999", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67999" } ] } ] }, { "uniprot_ac": "P68181", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68181" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68181" } ] } ] }, { "uniprot_ac": "P68182", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68182" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68182" } ] } ] }, { "uniprot_ac": "P68400", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68400" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68400" } ] } ] }, { "uniprot_ac": "P68403", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68403" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P68403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68403" } ] } ] }, { "uniprot_ac": "P68404", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68404", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68404" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P68404", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68404" } ] } ] }, { "uniprot_ac": "P70218", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70218" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70218" } ] } ] }, { "uniprot_ac": "P70236", "gene_name": "Map2k6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70236" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P70236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70236" } ] } ] }, { "uniprot_ac": "P70268", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70268" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P70268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70268" } ] } ] }, { "uniprot_ac": "P70335", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70335" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70335" } ] } ] }, { "uniprot_ac": "P70336", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70336" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70336" } ] } ] }, { "uniprot_ac": "P70618", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P70618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70618" } ] } ] }, { "uniprot_ac": "P78362", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78362" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78362" } ] } ] }, { "uniprot_ac": "P78368", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78368" } ] } ] }, { "uniprot_ac": "P78527", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78527" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78527" } ] } ] }, { "uniprot_ac": "P79621", "gene_name": "Ciita", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] } ] }, { "uniprot_ac": "P80192", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P80192", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80192" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P80192", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80192" } ] } ] }, { "uniprot_ac": "P83098", "gene_name": "Stlk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83098" } ] } ] }, { "uniprot_ac": "P83099", "gene_name": "Pkcdelta", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] } ] }, { "uniprot_ac": "P83100", "gene_name": "p38c", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83100" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83100" } ] } ] }, { "uniprot_ac": "P83102", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83102" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83102" } ] } ] }, { "uniprot_ac": "P83103", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83103" } ] } ] }, { "uniprot_ac": "P83104", "gene_name": "Takl1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83104" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83104" } ] } ] }, { "uniprot_ac": "P83510", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83510" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83510" } ] } ] }, { "uniprot_ac": "P83741", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83741" } ] } ] }, { "uniprot_ac": "P92208", "gene_name": "bsk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P92208" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P92208" } ] } ] }, { "uniprot_ac": "P97313", "gene_name": "Prkdc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97313" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97313" } ] } ] }, { "uniprot_ac": "P97343", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97343" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97343" } ] } ] }, { "uniprot_ac": "P97377", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97377", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97377" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P97377", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97377" } ] } ] }, { "uniprot_ac": "P97477", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97477", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97477" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97477", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97477" } ] } ] }, { "uniprot_ac": "P97633", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97633" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97633" } ] } ] }, { "uniprot_ac": "P97756", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] } ] }, { "uniprot_ac": "P97820", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97820", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97820" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97820", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97820" } ] } ] }, { "uniprot_ac": "P97874", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97874" } ] } ] }, { "uniprot_ac": "P97924", "gene_name": "Kalrn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97924" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97924" } ] } ] }, { "uniprot_ac": "Q00168", "gene_name": "CaMKII", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00168" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00168" } ] } ] }, { "uniprot_ac": "Q00526", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00526" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00526" } ] } ] }, { "uniprot_ac": "Q00532", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00532" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00532" } ] } ] }, { "uniprot_ac": "Q00534", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00534" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00534" } ] } ] }, { "uniprot_ac": "Q00535", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00535" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q00535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00535" } ] } ] }, { "uniprot_ac": "Q00536", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00536" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00536" } ] } ] }, { "uniprot_ac": "Q00537", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00537" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00537" } ] } ] }, { "uniprot_ac": "Q00772", "gene_name": "SLT2", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00772" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q00772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00772" } ] } ] }, { "uniprot_ac": "Q00972", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] } ] }, { "uniprot_ac": "Q01389", "gene_name": "BCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01389" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01389" } ] } ] }, { "uniprot_ac": "Q01919", "gene_name": "KIN4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01919" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01919" } ] } ] }, { "uniprot_ac": "Q01986", "gene_name": "Map2k1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01986" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q01986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01986" } ] } ] }, { "uniprot_ac": "Q02111", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02111" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02111" } ] } ] }, { "uniprot_ac": "Q02156", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02156" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02156" } ] } ] }, { "uniprot_ac": "Q02720", "gene_name": "casK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02720" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02720" } ] } ] }, { "uniprot_ac": "Q02750", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02750" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q02750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02750" } ] } ] }, { "uniprot_ac": "Q02779", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02779" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q02779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02779" } ] } ] }, { "uniprot_ac": "Q02956", "gene_name": "Prkcz", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02956" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02956" } ] } ] }, { "uniprot_ac": "Q03002", "gene_name": "FRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03002" } ] } ] }, { "uniprot_ac": "Q03042", "gene_name": "Pkg21D", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03042" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03042" } ] } ] }, { "uniprot_ac": "Q03043", "gene_name": "for", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03043" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03043" } ] } ] }, { "uniprot_ac": "Q03114", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03114", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03114" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03114", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03114" } ] } ] }, { "uniprot_ac": "Q03141", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03141" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03141" } ] } ] }, { "uniprot_ac": "Q03147", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] } ] }, { "uniprot_ac": "Q03306", "gene_name": "PKH3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03306" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03306" } ] } ] }, { "uniprot_ac": "Q03407", "gene_name": "PKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03407" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03407" } ] } ] }, { "uniprot_ac": "Q03497", "gene_name": "STE20", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03497" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03497" } ] } ] }, { "uniprot_ac": "Q03533", "gene_name": "TDA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03533" } ] } ] }, { "uniprot_ac": "Q03656", "gene_name": "SKY1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03656" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03656" } ] } ] }, { "uniprot_ac": "Q03785", "gene_name": "VHS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03785" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03785" } ] } ] }, { "uniprot_ac": "Q03963", "gene_name": "Eif2ak2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] } ] }, { "uniprot_ac": "Q04735", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04735" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q04735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04735" } ] } ] }, { "uniprot_ac": "Q04759", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04759" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q04759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04759" } ] } ] }, { "uniprot_ac": "Q04859", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04859", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04859" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04859", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04859" } ] } ] }, { "uniprot_ac": "Q04899", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04899", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04899" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q04899", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04899" } ] } ] }, { "uniprot_ac": "Q05512", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] } ] }, { "uniprot_ac": "Q05513", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05513" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q05513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05513" } ] } ] }, { "uniprot_ac": "Q05652", "gene_name": "pll", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] } ] }, { "uniprot_ac": "Q05655", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] }, { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] } ] }, { "uniprot_ac": "Q06098", "gene_name": "ISR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06098" } ] } ] }, { "uniprot_ac": "Q06226", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06226" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06226" } ] } ] }, { "uniprot_ac": "Q06486", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] } ] }, { "uniprot_ac": "Q07002", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07002" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q07002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07002" } ] } ] }, { "uniprot_ac": "Q07174", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07174" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q07174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07174" } ] } ] }, { "uniprot_ac": "Q07832", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07832" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q07832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07832" } ] } ] }, { "uniprot_ac": "Q07912", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] } ] }, { "uniprot_ac": "Q08217", "gene_name": "PSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q08217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08217" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08217" } ] } ] }, { "uniprot_ac": "Q08732", "gene_name": "HRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q08732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08732" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08732" } ] } ] }, { "uniprot_ac": "Q09013", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q09013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09013" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q09013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09013" } ] } ] }, { "uniprot_ac": "Q09137", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] } ] }, { "uniprot_ac": "Q0KHQ5", "gene_name": "Tao", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHQ5" } ] } ] }, { "uniprot_ac": "Q0KHT7", "gene_name": "Drak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHT7" } ] } ] }, { "uniprot_ac": "Q0KHV6", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHV6" } ] } ] }, { "uniprot_ac": "Q0KL02", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KL02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KL02" } ] } ] }, { "uniprot_ac": "Q12003", "gene_name": "ENV7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12003" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12003" } ] } ] }, { "uniprot_ac": "Q12100", "gene_name": "RTK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12100" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12100" } ] } ] }, { "uniprot_ac": "Q12152", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12152" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12152" } ] } ] }, { "uniprot_ac": "Q12196", "gene_name": "RIO1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] } ] }, { "uniprot_ac": "Q12222", "gene_name": "YGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12222" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12222" } ] } ] }, { "uniprot_ac": "Q12236", "gene_name": "PKH2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12236" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12236" } ] } ] }, { "uniprot_ac": "Q12263", "gene_name": "GIN4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12263" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12263" } ] } ] }, { "uniprot_ac": "Q12310", "gene_name": "PRR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12310" } ] } ] }, { "uniprot_ac": "Q12469", "gene_name": "SKM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12469" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12469" } ] } ] }, { "uniprot_ac": "Q12505", "gene_name": "SKS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12505" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12505" } ] } ] }, { "uniprot_ac": "Q12851", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12851" } ] } ] }, { "uniprot_ac": "Q12852", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12852" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q12852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12852" } ] } ] }, { "uniprot_ac": "Q12933", "gene_name": "TRAF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q12933", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12933" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q12933", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12933" } ] } ] }, { "uniprot_ac": "Q13043", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13043" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13043" } ] } ] }, { "uniprot_ac": "Q13131", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] } ] }, { "uniprot_ac": "Q13153", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13153" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13153" } ] } ] }, { "uniprot_ac": "Q13163", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13163" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q13163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13163" } ] } ] }, { "uniprot_ac": "Q13164", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13164" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q13164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13164" } ] } ] }, { "uniprot_ac": "Q13177", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13177" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13177" } ] } ] }, { "uniprot_ac": "Q13188", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13188" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13188" } ] } ] }, { "uniprot_ac": "Q13233", "gene_name": "MAP3K1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] }, { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] } ] }, { "uniprot_ac": "Q13237", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13237" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q13237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13237" } ] } ] }, { "uniprot_ac": "Q13315", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13315" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13315" } ] } ] }, { "uniprot_ac": "Q13418", "gene_name": "ILK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13418" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13418" } ] } ] }, { "uniprot_ac": "Q13464", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13464" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13464" } ] } ] }, { "uniprot_ac": "Q13523", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13523" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13523" } ] } ] }, { "uniprot_ac": "Q13535", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13535" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13535" } ] } ] }, { "uniprot_ac": "Q13546", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13546" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13546" } ] } ] }, { "uniprot_ac": "Q13554", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13554" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13554" } ] } ] }, { "uniprot_ac": "Q13555", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13555" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13555" } ] } ] }, { "uniprot_ac": "Q13557", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13557" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13557" } ] } ] }, { "uniprot_ac": "Q13627", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] } ] }, { "uniprot_ac": "Q13976", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13976" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q13976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13976" } ] } ] }, { "uniprot_ac": "Q14004", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] } ] }, { "uniprot_ac": "Q14012", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14012" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q14012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14012" } ] } ] }, { "uniprot_ac": "Q14296", "gene_name": "FASTK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.8", "activity": "ATP + L-threonyl-[Fas-activated protein] = ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein].", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.8", "activity": "", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] } ] }, { "uniprot_ac": "Q14680", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] } ] }, { "uniprot_ac": "Q14AX6", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] } ] }, { "uniprot_ac": "Q15131", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15131" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q15131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15131" } ] } ] }, { "uniprot_ac": "Q15139", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15139" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q15139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15139" } ] } ] }, { "uniprot_ac": "Q15208", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15208" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15208" } ] } ] }, { "uniprot_ac": "Q15349", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15349" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15349" } ] } ] }, { "uniprot_ac": "Q15382", "gene_name": "RHEB", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q15382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15382" } ] } ] }, { "uniprot_ac": "Q15418", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15418" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15418" } ] } ] }, { "uniprot_ac": "Q15569", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15569" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q15569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15569" } ] } ] }, { "uniprot_ac": "Q15759", "gene_name": "MAPK11", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15759" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q15759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15759" } ] } ] }, { "uniprot_ac": "Q15772", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15772" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15772" } ] } ] }, { "uniprot_ac": "Q15831", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15831" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15831" } ] } ] }, { "uniprot_ac": "Q15907", "gene_name": "RAB11B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "Q15907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15907" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q15907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15907" } ] } ] }, { "uniprot_ac": "Q16512", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16512" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q16512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16512" } ] } ] }, { "uniprot_ac": "Q16513", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16513" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q16513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16513" } ] } ] }, { "uniprot_ac": "Q16539", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16539" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16539" } ] } ] }, { "uniprot_ac": "Q16566", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16566" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q16566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16566" } ] } ] }, { "uniprot_ac": "Q16584", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16584" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q16584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16584" } ] } ] }, { "uniprot_ac": "Q16644", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q16644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16644" } ] } ] }, { "uniprot_ac": "Q16659", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] } ] }, { "uniprot_ac": "Q16816", "gene_name": "PHKG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] } ] }, { "uniprot_ac": "Q1EG27", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1EG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1EG27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1EG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1EG27" } ] } ] }, { "uniprot_ac": "Q1HKZ5", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1HKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HKZ5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q1HKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HKZ5" } ] } ] }, { "uniprot_ac": "Q1ZXC8", "gene_name": "pXi", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXC8" } ] } ] }, { "uniprot_ac": "Q1ZXD6", "gene_name": "roco5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXD6" } ] } ] }, { "uniprot_ac": "Q1ZXH2", "gene_name": "fhkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXH2" } ] } ] }, { "uniprot_ac": "Q1ZXI5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXI5" } ] } ] }, { "uniprot_ac": "Q1ZXR2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXR2" } ] } ] }, { "uniprot_ac": "Q23915", "gene_name": "kinX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q23915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23915" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q23915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23915" } ] } ] }, { "uniprot_ac": "Q23977", "gene_name": "hep", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23977" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23977" } ] } ] }, { "uniprot_ac": "Q24210", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24210" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24210" } ] } ] }, { "uniprot_ac": "Q24324", "gene_name": "Dsor1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24324" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24324" } ] } ] }, { "uniprot_ac": "Q2M2I8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q2M2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2M2I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2M2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2M2I8" } ] } ] }, { "uniprot_ac": "Q2NL51", "gene_name": "Gsk3a", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] } ] }, { "uniprot_ac": "Q38SD2", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q38SD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q38SD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q38SD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q38SD2" } ] } ] }, { "uniprot_ac": "Q3MJK5", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] } ] }, { "uniprot_ac": "Q3TYD6", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3TYD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TYD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3TYD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TYD6" } ] } ] }, { "uniprot_ac": "Q3TZA2", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3TZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TZA2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3TZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TZA2" } ] } ] }, { "uniprot_ac": "Q3U1V8", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U1V8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q3U1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U1V8" } ] } ] }, { "uniprot_ac": "Q3U214", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U214" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3U214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U214" } ] } ] }, { "uniprot_ac": "Q3U3Q1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U3Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3U3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U3Q1" } ] } ] }, { "uniprot_ac": "Q3UGM2", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UGM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UGM2" } ] } ] }, { "uniprot_ac": "Q3UH66", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UH66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UH66" } ] } ] }, { "uniprot_ac": "Q3UHC2", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHC2" } ] } ] }, { "uniprot_ac": "Q3UHJ0", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHJ0" } ] } ] }, { "uniprot_ac": "Q3ULB5", "gene_name": "Pak6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3ULB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3ULB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3ULB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3ULB5" } ] } ] }, { "uniprot_ac": "Q3UMM4", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMM4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3UMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMM4" } ] } ] }, { "uniprot_ac": "Q3UMW7", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMW7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMW7" } ] } ] }, { "uniprot_ac": "Q3UT86", "gene_name": "Gm5891", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UT86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UT86" } ] } ] }, { "uniprot_ac": "Q3UTA8", "gene_name": "Gm4567", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UTA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UTA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTA8" } ] } ] }, { "uniprot_ac": "Q3UTQ8", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UTQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3UTQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTQ8" } ] } ] }, { "uniprot_ac": "Q3UU96", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UU96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UU96" } ] } ] }, { "uniprot_ac": "Q3UVC0", "gene_name": "Ksr2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVC0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVC0" } ] } ] }, { "uniprot_ac": "Q3UVR3", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVR3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVR3" } ] } ] }, { "uniprot_ac": "Q3V016", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V016" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3V016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V016" } ] } ] }, { "uniprot_ac": "Q3V129", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V129" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3V129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V129" } ] } ] }, { "uniprot_ac": "Q3V3A1", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V3A1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3V3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V3A1" } ] } ] }, { "uniprot_ac": "Q4FZD7", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4FZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4FZD7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q4FZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4FZD7" } ] } ] }, { "uniprot_ac": "Q4G050", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4G050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G050" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4G050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G050" } ] } ] }, { "uniprot_ac": "Q4KLN3", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KLN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4KLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KLN3" } ] } ] }, { "uniprot_ac": "Q4KM34", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KM34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM34" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q4KM34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM34" } ] } ] }, { "uniprot_ac": "Q4KM47", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM47" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q4KM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM47" } ] } ] }, { "uniprot_ac": "Q4KSH6", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q4KSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH6" } ] } ] }, { "uniprot_ac": "Q4KSH7", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q4KSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH7" } ] } ] }, { "uniprot_ac": "Q4V793", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4V793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4V793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V793" } ] } ] }, { "uniprot_ac": "Q4V8A3", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4V8A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V8A3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4V8A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V8A3" } ] } ] }, { "uniprot_ac": "Q52WX2", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q52WX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q52WX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q52WX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q52WX2" } ] } ] }, { "uniprot_ac": "Q53UA7", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q53UA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q53UA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q53UA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q53UA7" } ] } ] }, { "uniprot_ac": "Q54B33", "gene_name": "pakE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54B33", "database": 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"evidence": [ { "id": "Q54BC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BC9" } ] } ] }, { "uniprot_ac": "Q54BF0", "gene_name": "fhkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54BF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54BF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BF0" } ] } ] }, { "uniprot_ac": "Q54C18", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54C18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54C18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C18" } ] } ] }, { 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"Q54P47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P47" } ] } ] }, { "uniprot_ac": "Q54PK8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK8" } ] } ] }, { "uniprot_ac": "Q54PK9", "gene_name": "pdkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK9" } ] } ] }, { "uniprot_ac": "Q54PX0", 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"2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QB1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q54QB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QB1" } ] } ] }, { "uniprot_ac": "Q54QD5", "gene_name": "nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QD5" } ] } ] }, { "uniprot_ac": "Q54QI2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QI2" } ] } ] }, { "uniprot_ac": "Q54QQ1", "gene_name": "phg2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QQ1" } ] } ] }, { "uniprot_ac": "Q54QV3", "gene_name": "yakA", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QV3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q54QV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QV3" } ] } ] }, { "uniprot_ac": "Q54R82", "gene_name": "mkkA", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54R82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R82" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q54R82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R82" } ] } ] }, { "uniprot_ac": "Q54R95", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54R95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54R95", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprot/Q55FJ6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q55FJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FJ6" } ] } ] }, { "uniprot_ac": "Q55FS2", "gene_name": "krsB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FS2" } ] } ] }, { "uniprot_ac": "Q55FT4", "gene_name": "tsuA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FT4" } ] } ] }, { "uniprot_ac": "Q55FV4", "gene_name": "fnkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV4" } ] } ] }, { "uniprot_ac": "Q55FV5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV5" } ] } ] }, { "uniprot_ac": "Q55GC2", "gene_name": "dst2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GC2" } ] } ] }, { "uniprot_ac": "Q55GE6", "gene_name": "roco7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GE6" } ] } ] }, { "uniprot_ac": "Q55GG4", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GG4" } ] } ] }, { "uniprot_ac": "Q55GJ2", "gene_name": "ireA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GJ2" } ] } ] }, { "uniprot_ac": "Q55GS4", "gene_name": "cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GS4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q55GS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GS4" } ] } ] }, { "uniprot_ac": "Q55GU0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GU0" } ] } ] }, { "uniprot_ac": "Q55GV3", "gene_name": "pakC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GV3" } ] } ] }, { "uniprot_ac": "Q56UN5", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] } ] }, { "uniprot_ac": "Q59H18", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q59H18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q59H18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q59H18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q59H18" } ] } ] }, { "uniprot_ac": "Q5EAK6", "gene_name": "tefu", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EAK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EAK6" } ] } ] }, { "uniprot_ac": "Q5EG47", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] } ] }, { "uniprot_ac": "Q5F2E8", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP 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"UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MAI5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5MAI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MAI5" } ] } ] }, { "uniprot_ac": "Q5MJS3", "gene_name": "Fam20c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MJS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5MJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MJS3" } ] } ] }, { "uniprot_ac": "Q5MPA9", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MPA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MPA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5MPA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MPA9" } ] } ] }, { "uniprot_ac": "Q5PQT0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5PQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5PQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT0" } ] } ] }, { "uniprot_ac": "Q5RJI5", "gene_name": "Brsk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] } ] }, { "uniprot_ac": "Q5RKH1", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5RKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKH1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5RKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKH1" } ] } ] }, { "uniprot_ac": "Q5S006", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + 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"https://www.uniprot.org/uniprot/Q5S007" } ] } ] }, { "uniprot_ac": "Q5SUV5", "gene_name": "Mylk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5SUV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SUV5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SUV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SUV5" } ] } ] }, { "uniprot_ac": "Q5SYL1", "gene_name": "Rskr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5SYL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SYL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SYL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SYL1" } ] } ] }, { "uniprot_ac": "Q5TCX8", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5TCX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCX8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q5TCX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCX8" } ] } ] }, { "uniprot_ac": "Q5TCY1", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5TCY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5TCY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCY1" } ] } ] }, { "uniprot_ac": "Q5U2N4", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U2N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U2N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2N4" } ] } ] }, { "uniprot_ac": "Q5U2X5", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] } ] }, { "uniprot_ac": "Q5U452", "gene_name": "Trp53rka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U452" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U452" } ] } ] }, { "uniprot_ac": "Q5U4C9", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U4C9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5U4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U4C9" } ] } ] }, { "uniprot_ac": "Q5VJL3", "gene_name": "gdt9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VJL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VJL3" } ] } ] }, { "uniprot_ac": "Q5VST9", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VST9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VST9" } ] } ] }, { "uniprot_ac": "Q5VT25", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VT25" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VT25" } ] } ] }, { "uniprot_ac": "Q5VZM2", "gene_name": "RRAGB", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5VZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VZM2" } ] } ] }, { "uniprot_ac": "Q5XIS9", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q5XIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS9" } ] } ] }, { "uniprot_ac": "Q5XIT0", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIT0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIT0" } ] } ] }, { "uniprot_ac": "Q5XJV6", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5XJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XJV6" } ] } ] }, { "uniprot_ac": "Q60592", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60592" } ] } ] }, { "uniprot_ac": "Q60670", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60670" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60670" } ] } ] }, { "uniprot_ac": "Q60700", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60700" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q60700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60700" } ] } ] }, { "uniprot_ac": "Q60737", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60737" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60737" } ] } ] }, { "uniprot_ac": "Q60806", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60806" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q60806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60806" } ] } ] }, { "uniprot_ac": "Q60823", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60823" } ] } ] }, { "uniprot_ac": "Q60855", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60855" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60855" } ] } ] }, { "uniprot_ac": "Q61036", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61036", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61036" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61036", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61036" } ] } ] }, { "uniprot_ac": "Q61083", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61083" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q61083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61083" } ] } ] }, { "uniprot_ac": "Q61084", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61084" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q61084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61084" } ] } ] }, { "uniprot_ac": "Q61097", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61097" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61097" } ] } ] }, { "uniprot_ac": "Q61136", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] } ] }, { "uniprot_ac": "Q61161", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61161" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61161" } ] } ] }, { "uniprot_ac": "Q61214", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] } ] }, { "uniprot_ac": "Q61241", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61241" } ] } ] }, { "uniprot_ac": "Q61410", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61410" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q61410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61410" } ] } ] }, { "uniprot_ac": "Q61532", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61532" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q61532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61532" } ] } ] }, { "uniprot_ac": "Q61831", "gene_name": "Mapk10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61831" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q61831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61831" } ] } ] }, { "uniprot_ac": "Q61846", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] } ] }, { "uniprot_ac": "Q62070", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62070" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62070" } ] } ] }, { "uniprot_ac": "Q62073", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62073" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q62073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62073" } ] } ] }, { "uniprot_ac": "Q62074", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62074" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q62074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62074" } ] } ] }, { "uniprot_ac": "Q62101", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62101" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q62101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62101" } ] } ] }, { "uniprot_ac": "Q62388", "gene_name": "Atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62388" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62388" } ] } ] }, { "uniprot_ac": "Q62406", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62406" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62406" } ] } ] }, { "uniprot_ac": "Q62407", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62407" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62407" } ] } ] }, { "uniprot_ac": "Q62673", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62673" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q62673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62673" } ] } ] }, { "uniprot_ac": "Q62726", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62726" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62726" } ] } ] }, { "uniprot_ac": "Q62761", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62761" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62761" } ] } ] }, { "uniprot_ac": "Q62762", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62762" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62762" } ] } ] }, { "uniprot_ac": "Q62763", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62763" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62763" } ] } ] }, { "uniprot_ac": "Q62829", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62829" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62829" } ] } ] }, { "uniprot_ac": "Q62862", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62862" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q62862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62862" } ] } ] }, { "uniprot_ac": "Q62868", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62868" } ] } ] }, { "uniprot_ac": "Q62915", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62915" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62915" } ] } ] }, { "uniprot_ac": "Q62925", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62925", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62925" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q62925", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62925" } ] } ] }, { "uniprot_ac": "Q63117", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63117" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63117" } ] } ] }, { "uniprot_ac": "Q63184", "gene_name": "Eif2ak2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] } ] }, { "uniprot_ac": "Q63185", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63185" } ] } ] }, { "uniprot_ac": "Q63285", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63285" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63285" } ] } ] }, { "uniprot_ac": "Q63433", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63433" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q63433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63433" } ] } ] }, { "uniprot_ac": "Q63450", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63450" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q63450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63450" } ] } ] }, { "uniprot_ac": "Q63454", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63454" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63454" } ] } ] }, { "uniprot_ac": "Q63470", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] } ] }, { "uniprot_ac": "Q63484", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63484" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63484" } ] } ] }, { "uniprot_ac": "Q63531", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63531" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63531" } ] } ] }, { "uniprot_ac": "Q63538", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63538" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63538" } ] } ] }, { "uniprot_ac": "Q63553", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63553" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63553" } ] } ] }, { "uniprot_ac": "Q63562", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63562" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q63562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63562" } ] } ] }, { "uniprot_ac": "Q63572", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63572" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63572" } ] } ] }, { "uniprot_ac": "Q63638", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63638" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63638" } ] } ] }, { "uniprot_ac": "Q63644", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63644" } ] } ] }, { "uniprot_ac": "Q63686", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63686" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q63686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63686" } ] } ] }, { "uniprot_ac": "Q63699", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63699" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q63699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63699" } ] } ] }, { "uniprot_ac": "Q63796", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63796" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q63796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63796" } ] } ] }, { "uniprot_ac": "Q63844", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63844" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63844" } ] } ] }, { "uniprot_ac": "Q63932", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63932" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q63932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63932" } ] } ] }, { "uniprot_ac": "Q63945", "gene_name": "Set", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63945" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q63945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63945" } ] } ] }, { "uniprot_ac": "Q641K5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q641K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641K5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q641K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641K5" } ] } ] }, { "uniprot_ac": "Q641Z4", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] } ] }, { "uniprot_ac": "Q64261", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64261" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q64261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64261" } ] } ] }, { "uniprot_ac": "Q64303", "gene_name": "Pak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64303" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q64303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64303" } ] } ] }, { "uniprot_ac": "Q64595", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64595" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q64595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64595" } ] } ] }, { "uniprot_ac": "Q64617", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64617" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q64617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64617" } ] } ] }, { "uniprot_ac": "Q64702", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] } ] }, { "uniprot_ac": "Q66H84", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66H84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q66H84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H84" } ] } ] }, { "uniprot_ac": "Q66HA1", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HA1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q66HA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HA1" } ] } ] }, { "uniprot_ac": "Q66HE5", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q66HE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE5" } ] } ] }, { "uniprot_ac": "Q66HE7", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q66HE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE7" } ] } ] }, { "uniprot_ac": "Q66L42", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66L42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66L42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q66L42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66L42" } ] } ] }, { "uniprot_ac": "Q69Z98", "gene_name": "Brsk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] } ] }, { "uniprot_ac": "Q69ZA1", "gene_name": "Cdk13", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] } ] }, { "uniprot_ac": "Q69ZM6", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69ZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q69ZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZM6" } ] } ] }, { "uniprot_ac": "Q6A1A2", "gene_name": "PDPK2P", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6A1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6A1A2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6A1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6A1A2" } ] } ] }, { "uniprot_ac": "Q6B9X6", "gene_name": "vwkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6B9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B9X6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6B9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B9X6" } ] } ] }, { "uniprot_ac": "Q6DT37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6DT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DT37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6DT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DT37" } ] } ] }, { "uniprot_ac": "Q6IQ55", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6IQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6IQ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6IQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6IQ55" } ] } ] }, { "uniprot_ac": "Q6P0Q8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P0Q8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P0Q8" } ] } ] }, { "uniprot_ac": "Q6P2M8", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P2M8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q6P2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P2M8" } ] } ] }, { "uniprot_ac": "Q6P3R8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P3R8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P3R8" } ] } ] }, { "uniprot_ac": "Q6P4S6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4S6" } ] } ] }, { "uniprot_ac": "Q6P5G0", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5G0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q6P5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5G0" } ] } ] }, { "uniprot_ac": "Q6P5Z2", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P5Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5Z2" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q6P5Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5Z2" } ] } ] }, { "uniprot_ac": "Q6P9R2", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9R2" } ] } ] }, { "uniprot_ac": "Q6PAJ1", "gene_name": "Bcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PAJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PAJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PAJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PAJ1" } ] } ] }, { "uniprot_ac": "Q6PCN3", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PCN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PCN3" } ] } ] }, { "uniprot_ac": "Q6PGN3", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PGN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PGN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PGN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PGN3" } ] } ] }, { "uniprot_ac": "Q6PHR2", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHR2" } ] } ] }, { "uniprot_ac": "Q6PHZ2", "gene_name": "Camk2d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHZ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q6PHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHZ2" } ] } ] }, { "uniprot_ac": "Q6SA08", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6SA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6SA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6SA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6SA08" } ] } ] }, { "uniprot_ac": "Q6V9V9", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9V9" } ] } ] }, { "uniprot_ac": "Q6V9Y2", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y2" } ] } ] }, { "uniprot_ac": "Q6V9Y3", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y3" } ] } ] }, { "uniprot_ac": "Q6VAB6", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6VAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6VAB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6VAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6VAB6" } ] } ] }, { "uniprot_ac": "Q6XHA5", "gene_name": "roco11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XHA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6XHA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA5" } ] } ] }, { "uniprot_ac": "Q6XHA7", "gene_name": "roco9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XHA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6XHA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA7" } ] } ] }, { "uniprot_ac": "Q6XHB2", "gene_name": "roco4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XHB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6XHB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHB2" } ] } ] }, { "uniprot_ac": "Q6XUX1", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX1" } ] } ] }, { "uniprot_ac": "Q6XUX2", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX2" } ] } ] }, { "uniprot_ac": "Q6XUX3", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX3" } ] } ] }, { "uniprot_ac": "Q6ZMQ8", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZMQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZMQ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZMQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZMQ8" } ] } ] }, { "uniprot_ac": "Q6ZN16", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZN16" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q6ZN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZN16" } ] } ] }, { "uniprot_ac": "Q6ZQ29", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZQ29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZQ29" } ] } ] }, { "uniprot_ac": "Q6ZWH5", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZWH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZWH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZWH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZWH5" } ] } ] }, { "uniprot_ac": "Q70PP2", "gene_name": "nonC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q70PP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q70PP2" } ] } ] }, { "uniprot_ac": "Q75JK0", "gene_name": "zakA", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q75JK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JK0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q75JK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JK0" } ] } ] }, { "uniprot_ac": "Q75JN1", "gene_name": "ifkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q75JN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q75JN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JN1" } ] } ] }, { "uniprot_ac": "Q76MJ5", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] } ] }, { "uniprot_ac": "Q76NV1", "gene_name": "dyrk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76NV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76NV1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q76NV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76NV1" } ] } ] }, { "uniprot_ac": "Q76P07", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76P07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76P07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q76P07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76P07" } ] } ] }, { "uniprot_ac": "Q7KRY6", "gene_name": "ball", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KRY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KRY6" } ] } ] }, { "uniprot_ac": "Q7KZI7", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] } ] }, { "uniprot_ac": "Q7L523", "gene_name": "RRAGA", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q7L523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L523" } ] } ] }, { "uniprot_ac": "Q7L7X3", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7L7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L7X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7L7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L7X3" } ] } ] }, { "uniprot_ac": "Q7PLI7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7PLI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7PLI7" } ] } ] }, { "uniprot_ac": "Q7TNJ7", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNJ7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q7TNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNJ7" } ] } ] }, { "uniprot_ac": "Q7TNL3", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL3" } ] } ] }, { "uniprot_ac": "Q7TNL4", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL4" } ] } ] }, { "uniprot_ac": "Q7TPK6", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TPK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TPK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPK6" } ] } ] }, { "uniprot_ac": "Q7TPS0", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPS0" } ] } ] }, { "uniprot_ac": "Q7TQP6", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TQP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TQP6" } ] } ] }, { "uniprot_ac": "Q7TSC3", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSC3" } ] } ] }, { "uniprot_ac": "Q7TSE6", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSE6" } ] } ] }, { "uniprot_ac": "Q7TSJ6", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSJ6" } ] } ] }, { "uniprot_ac": "Q7TT49", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT49" } ] } ] }, { "uniprot_ac": "Q7TT50", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TT50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT50" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TT50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT50" } ] } ] }, { "uniprot_ac": "Q7Z2Y5", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7Z2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7Z2Y5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7Z2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7Z2Y5" } ] } ] }, { "uniprot_ac": "Q80TR8", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80TR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TR8" } ] } ] }, { "uniprot_ac": "Q80UE6", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UE6" } ] } ] }, { "uniprot_ac": "Q80UV9", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] } ] }, { "uniprot_ac": "Q80UW5", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UW5" } ] } ] }, { "uniprot_ac": "Q80X41", "gene_name": "Vrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80X41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80X41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80X41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80X41" } ] } ] }, { "uniprot_ac": "Q80XI6", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80XI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XI6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q80XI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XI6" } ] } ] }, { "uniprot_ac": "Q80XP9", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80XP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80XP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XP9" } ] } ] }, { "uniprot_ac": "Q80Y86", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Y86" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q80Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Y86" } ] } ] }, { "uniprot_ac": "Q80YE4", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80YE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE4" } ] } ] }, { "uniprot_ac": "Q80YE7", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80YE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE7" } ] } ] }, { "uniprot_ac": "Q80YP0", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YP0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q80YP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YP0" } ] } ] }, { "uniprot_ac": "Q80ZW0", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80ZW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80ZW0" } ] } ] }, { "uniprot_ac": "Q810W7", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q810W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810W7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q810W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810W7" } ] } ] }, { "uniprot_ac": "Q811L6", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q811L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q811L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q811L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q811L6" } ] } ] }, { "uniprot_ac": "Q869L4", "gene_name": "fnkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869L4" } ] } ] }, { "uniprot_ac": "Q869N2", "gene_name": "pakB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869N2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869N2" } ] } ] }, { "uniprot_ac": "Q869T7", "gene_name": "pakF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869T7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869T7" } ] } ] }, { "uniprot_ac": "Q869X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869X3" } ] } ] }, { "uniprot_ac": "Q86A12", "gene_name": "sky1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86A12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86A12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86A12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86A12" } ] } ] }, { "uniprot_ac": "Q86AE1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86AE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86AE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AE1" } ] } ] }, { "uniprot_ac": "Q86AT8", "gene_name": "spkA-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86AT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86AT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AT8" } ] } ] }, { "uniprot_ac": "Q86C65", "gene_name": "tor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86C65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86C65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86C65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86C65" } ] } ] }, { "uniprot_ac": "Q86CS2", "gene_name": "atg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86CS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86CS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86CS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86CS2" } ] } ] }, { "uniprot_ac": "Q86HG9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HG9" } ] } ] }, { "uniprot_ac": "Q86HN7", "gene_name": "PLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HN7" } ] } ] }, { "uniprot_ac": "Q86HW6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HW6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HW6" } ] } ] }, { "uniprot_ac": "Q86I06", "gene_name": "nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86I06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86I06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86I06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86I06" } ] } ] }, { "uniprot_ac": "Q86IX1", "gene_name": "dst1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86IX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86IX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IX1" } ] } ] }, { "uniprot_ac": "Q86SG6", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86SG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86SG6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86SG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86SG6" } ] } ] }, { "uniprot_ac": "Q86TB3", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86TB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86TB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86TB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86TB3" } ] } ] }, { "uniprot_ac": "Q86UE8", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86UE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86UE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UE8" } ] } ] }, { "uniprot_ac": "Q86UX6", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86UX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86UX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UX6" } ] } ] }, { "uniprot_ac": "Q86V86", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86V86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86V86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V86" } ] } ] }, { "uniprot_ac": "Q86Y07", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86Y07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Y07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86Y07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Y07" } ] } ] }, { "uniprot_ac": "Q86YV6", "gene_name": "MYLK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86YV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86YV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86YV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86YV6" } ] } ] }, { "uniprot_ac": "Q86Z02", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86Z02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Z02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86Z02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Z02" } ] } ] }, { "uniprot_ac": "Q8BG48", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG48" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG48" } ] } ] }, { "uniprot_ac": "Q8BGW6", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BGW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGW6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BGW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGW6" } ] } ] }, { "uniprot_ac": "Q8BHI9", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BHI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BHI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHI9" } ] } ] }, { "uniprot_ac": "Q8BI55", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BI55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BI55" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q8BI55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BI55" } ] } ] }, { "uniprot_ac": "Q8BK63", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK63" } ] } ] }, { "uniprot_ac": "Q8BKX6", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BKX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BKX6" } ] } ] }, { "uniprot_ac": "Q8BLF2", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BLF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLF2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8BLF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLF2" } ] } ] }, { "uniprot_ac": "Q8BLK9", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BLK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLK9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BLK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLK9" } ] } ] }, { "uniprot_ac": "Q8BN21", "gene_name": "Vrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BN21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BN21" } ] } ] }, { "uniprot_ac": "Q8BPM2", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BPM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BPM2" } ] } ] }, { "uniprot_ac": "Q8BRK8", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] } ] }, { "uniprot_ac": "Q8BSK8", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + 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"https://www.uniprot.org/uniprot/Q8BTI9" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] } ] }, { "uniprot_ac": "Q8BTW9", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTW9" } ] } ] }, { "uniprot_ac": "Q8BVP5", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BVP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BVP5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BVP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BVP5" } ] } ] }, { "uniprot_ac": "Q8BW96", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BW96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BW96" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8BW96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BW96" } ] } ] }, { "uniprot_ac": "Q8BWD8", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWD8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8BWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWD8" } ] } ] }, { "uniprot_ac": "Q8BWE1", "gene_name": "1810024B03Rik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWE1" } ] } ] }, { "uniprot_ac": "Q8BWQ5", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWQ5", "database": "UniProtKB", "url": 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"Q8BYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYC6" } ] } ] }, { "uniprot_ac": "Q8BYR2", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYR2" } ] } ] }, { "uniprot_ac": "Q8BZ03", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ03" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ03" } ] } ] }, { "uniprot_ac": "Q8BZ25", "gene_name": "Ankk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ25" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ25" } ] } ] }, { "uniprot_ac": "Q8BZN4", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BZN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZN4" } ] } ] }, { "uniprot_ac": "Q8C015", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP 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H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C1R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C1R0" } ] } ] }, { "uniprot_ac": "Q8C4X2", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C4X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C4X2" } ] } ] }, { "uniprot_ac": "Q8CDB0", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CDB0", "database": "UniProtKB", "url": 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"Q8CIN4", "gene_name": "Pak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIN4" } ] } ] }, { "uniprot_ac": "Q8CIP4", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIP4" } ] } ] }, { "uniprot_ac": "Q8CIR4", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP 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"evidence": [ { "id": "Q8N165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N165" } ] } ] }, { "uniprot_ac": "Q8N2I9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N2I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N2I9" } ] } ] }, { "uniprot_ac": "Q8N4C8", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N4C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N4C8" } ] } ] }, { "uniprot_ac": "Q8N568", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N568" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N568" } ] } ] }, { "uniprot_ac": "Q8N5S9", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N5S9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8N5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N5S9" } ] } ] }, { "uniprot_ac": "Q8N752", "gene_name": "CSNK1A1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N752" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N752" } ] } ] }, { "uniprot_ac": "Q8NE63", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NE63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NE63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NE63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NE63" } ] } ] }, { "uniprot_ac": "Q8NEB9", "gene_name": "PIK3C3", "activity": [ { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "Q8NEB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEB9" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "Q8NEB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEB9" } ] } ] }, { "uniprot_ac": "Q8NEV1", "gene_name": "CSNK2A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV1" } ] } ] }, { "uniprot_ac": "Q8NEV4", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV4" } ] } ] }, { "uniprot_ac": "Q8NFD2", "gene_name": "ANKK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NFD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NFD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NFD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NFD2" } ] } ] }, { "uniprot_ac": "Q8NG66", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NG66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NG66" } ] } ] }, { "uniprot_ac": "Q8QZR7", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZR7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZR7" } ] } ] }, { "uniprot_ac": "Q8QZV4", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZV4" } ] } ] }, { "uniprot_ac": "Q8QZX0", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZX0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZX0" } ] } ] }, { "uniprot_ac": "Q8R2S1", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2S1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2S1" } ] } ] }, { "uniprot_ac": "Q8R3L8", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] } ] }, { "uniprot_ac": "Q8R4K2", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4K2" } ] } ] }, { "uniprot_ac": "Q8R4U9", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4U9" } ] } ] }, { "uniprot_ac": "Q8R4V0", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V0" } ] } ] }, { "uniprot_ac": "Q8SSS9", "gene_name": "qkgA-2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSS9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8SSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSS9" } ] } ] }, { "uniprot_ac": "Q8SSV3", "gene_name": "mkcD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8SSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSV3" } ] } ] }, { "uniprot_ac": "Q8SSY6", "gene_name": "", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q8SSY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSY6" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSY6" } ] } ] }, { "uniprot_ac": "Q8T0S6", "gene_name": "hpo", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T0S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T0S6" } ] } ] }, { "uniprot_ac": "Q8T2I8", "gene_name": "sepA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T2I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T2I8" } ] } ] }, { "uniprot_ac": "Q8T9L5", "gene_name": "Lkb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T9L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T9L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9L5" } ] } ] }, { "uniprot_ac": "Q8TAS1", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TAS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TAS1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TAS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TAS1" } ] } ] }, { "uniprot_ac": "Q8TD08", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD08" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q8TD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD08" } ] } ] }, { "uniprot_ac": "Q8TD19", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD19" } ] } ] }, { "uniprot_ac": "Q8TDC3", "gene_name": "BRSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] } ] }, { "uniprot_ac": "Q8TDR2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDR2" } ] } ] }, { "uniprot_ac": "Q8TDX7", "gene_name": "NEK7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDX7" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q8TDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDX7" } ] } ] }, { "uniprot_ac": "Q8TF76", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TF76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TF76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF76" } ] } ] }, { "uniprot_ac": "Q8VBY2", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VBY2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8VBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VBY2" } ] } ] }, { "uniprot_ac": "Q8VCT9", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VCT9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q8VCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VCT9" } ] } ] }, { "uniprot_ac": "Q8VD65", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD65" } ] } ] }, { "uniprot_ac": "Q8VDF3", "gene_name": "Dapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VDF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDF3" } ] } ] }, { "uniprot_ac": "Q8VDG6", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDG6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q8VDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDG6" } ] } ] }, { "uniprot_ac": "Q8VDU5", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDU5" } ] } ] }, { "uniprot_ac": "Q8VHF0", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VHF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VHF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHF0" } ] } ] }, { "uniprot_ac": "Q8VHJ5", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] } ] }, { "uniprot_ac": "Q8WU08", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WU08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WU08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WU08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WU08" } ] } ] }, { "uniprot_ac": "Q8WXR4", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WXR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WXR4" } ] } ] }, { "uniprot_ac": "Q8WZ42", "gene_name": "TTN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WZ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WZ42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WZ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WZ42" } ] } ] }, { "uniprot_ac": "Q91VB2", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91VB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VB2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q91VB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VB2" } ] } ] }, { "uniprot_ac": "Q91VJ4", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91VJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91VJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VJ4" } ] } ] }, { "uniprot_ac": "Q91XS8", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91XS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91XS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS8" } ] } ] }, { "uniprot_ac": "Q91Y86", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Y86" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q91Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Y86" } ] } ] }, { "uniprot_ac": "Q91YA2", "gene_name": "Pskh1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91YA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91YA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YA2" } ] } ] }, { "uniprot_ac": "Q91YS8", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91YS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YS8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q91YS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YS8" } ] } ] }, { "uniprot_ac": "Q91Z96", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91Z96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91Z96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z96" } ] } ] }, { "uniprot_ac": "Q91ZB0", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZB0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZB0" } ] } ] }, { "uniprot_ac": "Q91ZN7", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.4.99.18", "activity": "a dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = a dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-[protein].", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.4.99.18", "activity": "", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] } ] }, { "uniprot_ac": "Q91ZR4", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZR4" } ] } ] }, { "uniprot_ac": "Q922Q2", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] } ] }, { "uniprot_ac": "Q922R0", "gene_name": "Prkx", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q922R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922R0" } ] } ] }, { "uniprot_ac": "Q922Y0", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Y0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q922Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Y0" } ] } ] }, { "uniprot_ac": "Q923J1", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q923J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923J1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q923J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923J1" } ] } ] }, { "uniprot_ac": "Q923T9", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q923T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923T9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q923T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923T9" } ] } ] }, { "uniprot_ac": "Q924C5", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924C5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924C5" } ] } ] }, { "uniprot_ac": "Q924I2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924I2" } ] } ] }, { "uniprot_ac": "Q924U5", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924U5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q924U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924U5" } ] } ] }, { "uniprot_ac": "Q924X7", "gene_name": "Stk33", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924X7" } ] } ] }, { "uniprot_ac": "Q925B3", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925B3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q925B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925B3" } ] } ] }, { "uniprot_ac": "Q925D6", "gene_name": "Map2k6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925D6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q925D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925D6" } ] } ] }, { "uniprot_ac": "Q925K9", "gene_name": "Tssk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925K9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q925K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925K9" } ] } ] }, { "uniprot_ac": "Q92630", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92630" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q92630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92630" } ] } ] }, { "uniprot_ac": "Q92772", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92772" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q92772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92772" } ] } ] }, { "uniprot_ac": 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"id": "Q99683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99683" } ] } ] }, { "uniprot_ac": "Q99759", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99759" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q99759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99759" } ] } ] }, { "uniprot_ac": "Q99986", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99986" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99986" } ] } ] }, { 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"activity": "", "evidence": [ { "id": "Q99J95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J95" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q99J95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J95" } ] } ] }, { "uniprot_ac": "Q99JP0", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99JP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99JP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JP0" } ] } ] }, { "uniprot_ac": "Q99JT2", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99JT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99JT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JT2" } ] } ] }, { "uniprot_ac": "Q99KH8", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99KH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99KH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KH8" } ] } ] }, { "uniprot_ac": "Q99KY4", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KY4" } ] } ] }, { "uniprot_ac": "Q99MQ3", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99MQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99MQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MQ3" } ] } ] }, { "uniprot_ac": "Q99MW1", "gene_name": "Stk31", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99MW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99MW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MW1" } ] } ] }, { "uniprot_ac": "Q99N57", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99N57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N57" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99N57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N57" } ] } ] }, { "uniprot_ac": "Q99PW4", "gene_name": "Tp53rkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99PW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PW4" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q99PW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99PW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PW4" } ] } ] }, { "uniprot_ac": "Q9BQI3", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BQI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BQI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BQI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BQI3" } ] } ] }, { "uniprot_ac": "Q9BRS2", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] } ] }, { "uniprot_ac": "Q9BUB5", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BUB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BUB5" } ] } ] }, { "uniprot_ac": "Q9BVS4", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVS4" } ] } ] }, { "uniprot_ac": "Q9BWU1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BWU1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9BWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BWU1" } ] } ] }, { "uniprot_ac": "Q9BX84", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BX84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BX84" } ] } ] }, { "uniprot_ac": "Q9BXA6", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA6" } ] } ] }, { "uniprot_ac": "Q9BXA7", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA7" } ] } ] }, { "uniprot_ac": "Q9BXM7", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXM7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXM7" } ] } ] }, { "uniprot_ac": "Q9BXU1", "gene_name": "STK31", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXU1" } ] } ] }, { "uniprot_ac": "Q9BYP7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYP7" } ] } ] }, { "uniprot_ac": "Q9BYT3", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYT3" } ] } ] }, { "uniprot_ac": "Q9BZL6", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BZL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BZL6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9BZL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BZL6" } ] } ] }, { "uniprot_ac": "Q9C098", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9C098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9C098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9C098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9C098" } ] } ] }, { "uniprot_ac": "Q9CQS5", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9CQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9CQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQS5" } ] } ] }, { "uniprot_ac": "Q9CXB8", "gene_name": "Alpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9CXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CXB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9CXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CXB8" } ] } ] }, { "uniprot_ac": "Q9D2E1", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9D2E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D2E1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9D2E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D2E1" } ] } ] }, { "uniprot_ac": "Q9D411", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9D411", "database": "UniProtKB", "url": 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protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] } ] }, { "uniprot_ac": "Q9EQY0", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9EQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9EQY0" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q9EQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9EQY0" } ] } ] }, { "uniprot_ac": "Q9ERE3", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ERE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERE3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ERE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERE3" } ] } ] }, { "uniprot_ac": "Q9ERH7", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ERH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ERH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERH7" } ] } ] }, { "uniprot_ac": "Q9ERK0", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ERK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ERK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERK0" } ] } ] }, { "uniprot_ac": "Q9ES70", "gene_name": "Nek6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ES70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES70" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9ES70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES70" } ] } ] }, { "uniprot_ac": "Q9ES74", "gene_name": "Nek7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ES74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES74" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9ES74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES74" } ] } ] }, { "uniprot_ac": "Q9ESG9", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ESG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ESG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESG9" } ] } ] }, { "uniprot_ac": "Q9ESL4", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ESL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESL4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9ESL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESL4" } ] } ] }, { "uniprot_ac": "Q9H093", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H093" } ] } ] }, { "uniprot_ac": "Q9H0K1", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H0K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H0K1" } ] } ] }, { "uniprot_ac": "Q9H2G2", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2G2" } ] } ] }, { "uniprot_ac": "Q9H2K8", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2K8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2K8" } ] } ] }, { "uniprot_ac": "Q9H2X6", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2X6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2X6" } ] } ] }, { "uniprot_ac": "Q9H422", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H422" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H422" } ] } ] }, { "uniprot_ac": "Q9H4A3", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H4A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4A3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H4A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4A3" } ] } ] }, { "uniprot_ac": "Q9H4B4", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4B4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q9H4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4B4" } ] } ] }, { "uniprot_ac": "Q9HAZ1", "gene_name": "CLK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HAZ1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9HAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HAZ1" } ] } ] }, { "uniprot_ac": "Q9HB90", "gene_name": "RRAGC", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q9HB90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HB90" } ] } ] }, { "uniprot_ac": "Q9HBH9", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBH9" } ] } ] }, { "uniprot_ac": "Q9HBY8", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBY8" } ] } ] }, { "uniprot_ac": "Q9HC98", "gene_name": "NEK6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HC98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HC98" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9HC98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HC98" } ] } ] }, { "uniprot_ac": "Q9HCP0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HCP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HCP0" } ] } ] }, { "uniprot_ac": "Q9JHG7", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] } ] }, { "uniprot_ac": "Q9JHU3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHU3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHU3" } ] } ] }, { "uniprot_ac": "Q9JI10", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JI10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI10" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JI10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI10" } ] } ] }, { "uniprot_ac": "Q9JI11", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JI11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JI11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI11" } ] } ] }, { "uniprot_ac": "Q9JIH7", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JIH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JIH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIH7" } ] } ] }, { "uniprot_ac": "Q9JIX9", "gene_name": "Fastk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.8", "activity": "ATP + L-threonyl-[Fas-activated protein] = ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein].", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.8", "activity": "", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] } ] }, { "uniprot_ac": "Q9JJ78", "gene_name": "Pbk", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJ78" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q9JJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJ78" } ] } ] }, { "uniprot_ac": "Q9JJX8", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJX8" } ] } ] }, { "uniprot_ac": "Q9JKK8", "gene_name": "Atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKK8" } ] } ] }, { "uniprot_ac": "Q9JKV2", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JKV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JKV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKV2" } ] } ] }, { "uniprot_ac": "Q9JLM8", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLM8" } ] } ] }, { "uniprot_ac": "Q9JLN9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLN9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLN9" } ] } ] }, { "uniprot_ac": "Q9JLS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLS3" } ] } ] }, { "uniprot_ac": "Q9JM01", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM01" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9JM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM01" } ] } ] }, { "uniprot_ac": "Q9JM52", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM52" } ] } ] }, { "uniprot_ac": "Q9JMK2", "gene_name": "Csnk1e", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JMK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JMK2" } ] } ] }, { "uniprot_ac": "Q9NBK5", "gene_name": "trc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP 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} ] }, { "uniprot_ac": "Q9VJC2", "gene_name": "Dmel\\CG7094", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VJC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJC2" } ] } ] }, { "uniprot_ac": "Q9VK45", "gene_name": "mTor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VK45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VK45" } ] } ] }, { "uniprot_ac": "Q9VKN7", "gene_name": "aurB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VKN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VKN7" } ] } ] }, { "uniprot_ac": "Q9VL34", "gene_name": "Dmel\\CG4839", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VL34" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VL34" } ] } ] }, { "uniprot_ac": "Q9VM90", "gene_name": "meng", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VM90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VM90" } ] } ] }, { "uniprot_ac": "Q9VMY8", "gene_name": "aux", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VMY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VMY8" } ] } ] }, { "uniprot_ac": "Q9VN23", "gene_name": "CG10532", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VN23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VN23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VN23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VN23" } ] } ] }, { "uniprot_ac": "Q9VP22", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] } ] }, { "uniprot_ac": "Q9VPC0", "gene_name": "Pitslre", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VPC0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VPC0" } ] } ] }, { "uniprot_ac": "Q9VR42", "gene_name": "Dmel\\CG3008", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VR42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VR42" } ] } ] }, { "uniprot_ac": "Q9VRJ6", "gene_name": "Tcs5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VRJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VRJ6" } ] } ] }, { "uniprot_ac": "Q9VT57", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] } ] }, { "uniprot_ac": "Q9VTL5", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTL5" } ] } ] }, { "uniprot_ac": "Q9VUQ9", "gene_name": "dop", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUQ9" } ] } ] }, { "uniprot_ac": "Q9VUV4", "gene_name": "sff", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUV4" } ] } ] }, { "uniprot_ac": "Q9VW24", "gene_name": "wnd", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VW24" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VW24" } ] } ] }, { "uniprot_ac": "Q9VXE3", "gene_name": "Rok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE3" } ] } ] }, { "uniprot_ac": "Q9VXE5", "gene_name": "mbt", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE5" } ] } ] }, { "uniprot_ac": "Q9VXG8", "gene_name": "mei-41", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXG8" } ] } ] }, { "uniprot_ac": "Q9VXN5", "gene_name": "Dmel\\CG8565", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXN5" } ] } ] }, { "uniprot_ac": "Q9VZI2", "gene_name": "Ack", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] } ] }, { "uniprot_ac": "Q9W002", "gene_name": "msn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W002" } ] } ] }, { "uniprot_ac": "Q9W0V1", "gene_name": "Pdk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W0V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W0V1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W0V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W0V1" } ] } ] }, { "uniprot_ac": "Q9W1B0", "gene_name": "gek", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W1B0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W1B0" } ] } ] }, { "uniprot_ac": "Q9W354", "gene_name": "Erk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W354" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9W354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W354" } ] } ] }, { "uniprot_ac": "Q9W3N8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W3N8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W3N8" } ] } ] }, { "uniprot_ac": "Q9WTK7", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WTK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTK7" } ] } ] }, { "uniprot_ac": "Q9WTQ0", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9WTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ0" } ] } ] }, { "uniprot_ac": "Q9WTQ1", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9WTQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ1" } ] } ] }, { "uniprot_ac": "Q9WTR2", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTR2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTR2" } ] } ] }, { "uniprot_ac": "Q9WTU6", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTU6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WTU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTU6" } ] } ] }, { "uniprot_ac": "Q9WTY9", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTY9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTY9" } ] } ] }, { "uniprot_ac": "Q9WUA6", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUA6" } ] } ] }, { "uniprot_ac": "Q9WUI1", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUI1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUI1" } ] } ] }, { "uniprot_ac": "Q9WUL6", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUL6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9WUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUL6" } ] } ] }, { "uniprot_ac": "Q9WUN2", "gene_name": "Tbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUN2" } ] } ] }, { "uniprot_ac": "Q9WUT3", "gene_name": "Rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUT3" } ] } ] }, { "uniprot_ac": "Q9WV60", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] } ] }, { "uniprot_ac": "Q9WVC6", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVC6" } ] } ] }, { "uniprot_ac": "Q9WVS4", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9WVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS4" } ] } ] }, { "uniprot_ac": "Q9WVS7", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q9WVS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS7" } ] } ] }, { "uniprot_ac": "Q9WVS8", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS8" } ] } ] }, { "uniprot_ac": "Q9Y243", "gene_name": "AKT3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y243" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y243" } ] } ] }, { "uniprot_ac": "Q9Y2H1", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H1" } ] } ] }, { "uniprot_ac": "Q9Y2H9", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H9" } ] } ] }, { "uniprot_ac": "Q9Y2I7", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] } ] }, { "uniprot_ac": "Q9Y2K2", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2K2" } ] } ] }, { "uniprot_ac": "Q9Y2U5", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2U5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9Y2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2U5" } ] } ] }, { "uniprot_ac": "Q9Y3S1", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y3S1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y3S1" } ] } ] }, { "uniprot_ac": "Q9Y463", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y463" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9Y463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y463" } ] } ] }, { "uniprot_ac": "Q9Y4B6", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y4B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4B6" } ] } ] }, { "uniprot_ac": "Q9Y4K4", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y4K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y4K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K4" } ] } ] }, { "uniprot_ac": "Q9Y572", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y572" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y572" } ] } ] }, { "uniprot_ac": "Q9Y5S2", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y5S2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y5S2" } ] } ] }, { "uniprot_ac": "Q9Y6E0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y6E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6E0" } ] } ] }, { "uniprot_ac": "Q9Y6M4", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6M4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y6M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6M4" } ] } ] }, { "uniprot_ac": "Q9Y6R4", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6R4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9Y6R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6R4" } ] } ] }, { "uniprot_ac": "Q9Y6S9", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6S9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6S9" } ] } ] }, { "uniprot_ac": "Q9Z0G2", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z0G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z0G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0G2" } ] } ] }, { "uniprot_ac": "Q9Z0H0", "gene_name": "Cdc7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z0H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z0H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0H0" } ] } ] }, { "uniprot_ac": "Q9Z0R0", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0R0" } ] } ] }, { "uniprot_ac": "Q9Z188", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP 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"Q9Z2A0", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A0" } ] } ] }, { "uniprot_ac": "Q9Z2A6", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9Z2A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A6" } ] } ] }, { "uniprot_ac": "Q9Z2B5", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B5" } ] } ] }, { "uniprot_ac": "Q9Z2B9", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B9" } ] } ] }, { "uniprot_ac": "Q9Z2E3", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2E3" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q9Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2E3" } ] } ] }, { "uniprot_ac": "Q9Z2P5", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2P5" } ] } ] }, { "uniprot_ac": "Q9Z2R9", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 37 }, { "field": "total_sites", "count": 31 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 13 }, { "field": "total_sites", "count": 11 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": 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