{ "uniprot_canonical_ac": "O60729-1", "uniprot_ac": "O60729", "uniprot_id": "CC14B_HUMAN", "mass": { "chemical_mass": 56802.0, "monoisotopic_mass": 56802.0 }, "refseq": { "ac": "NP_001070649", "name": "dual specificity protein phosphatase CDC14B isoform 3", "summary": "The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" }, "gene_names": [ { "name": "CDC14B", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O60729", "id": "O60729" }, { "name": "CDC14B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649", "id": "NP_001070649" }, { "name": "Cdc14B1; Cdc14B2; CDC14B3; hCDC14B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649", "id": "NP_001070649" } ], "protein_names": [ { "name": "Dual specificity protein phosphatase CDC14B", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O60729" }, { "name": "3.1.3.16", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O60729" }, { "name": "3.1.3.48", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O60729" }, { "name": "CDC14 cell division cycle 14 homolog B", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O60729" }, { "name": "dual specificity protein phosphatase CDC14B isoform 3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649", "id": "NP_001070649" }, { "name": "dual specificity protein phosphatase CDC14B; CDC14 cell division cycle 14 homolog B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649", "id": "NP_001070649" } ], "function": [ { "annotation": "CDC14B is a favorable biomarker for recurrence and prognosis of GBM.", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" }, { "database": "PubMed", "id": "36898299", "url": "https://glygen.org/publication/PubMed/36898299" } ] }, { "annotation": "Downregulation of CDC14B in 5218 breast cancer patients: A novel prognosticator for triple-negative breast cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" }, { "database": "PubMed", "id": "33378938", "url": "https://glygen.org/publication/PubMed/33378938" } ] }, { "annotation": "Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729#function" }, { "database": "PubMed", "id": "18662541", "url": "https://glygen.org/publication/PubMed/18662541" }, { "database": "PubMed", "id": "9367992", "url": "https://glygen.org/publication/PubMed/9367992" }, { "database": "PubMed", "id": "17488717", "url": "https://glygen.org/publication/PubMed/17488717" } ] }, { "annotation": "Human cells lacking CDC14A and CDC14B show differences in ciliogenesis but not in mitotic progression. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" }, { "database": "PubMed", "id": "33328327", "url": "https://glygen.org/publication/PubMed/33328327" } ] }, { "annotation": "MiR-1247-5p Functions as a Tumor Suppressor in Human Astroglioma Cells by Targeting CDC14B.", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" }, { "database": "PubMed", "id": "32366555", "url": "https://glygen.org/publication/PubMed/32366555" } ] }, { "annotation": "The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans. Review article", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" }, { "database": "PubMed", "id": "37493185", "url": "https://glygen.org/publication/PubMed/37493185" } ] }, { "annotation": "The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "83.47", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "68.69", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "81.7", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "67.11", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "85.81", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "84.47", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "64.1", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "88.4", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "86.88", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "65.89", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "90.86", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "84.04", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "80.11", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000081377", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000081377" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "O60729", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60729" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL 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"name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, 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"http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, intestinal", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Urinary bladder cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "O60729", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60729" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ] } ] }, { "significant": "No", "trend": "down", "name": "Head and neck cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "O60729", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60729" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Lung cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1324", "evidence": [ { "database": "BioXpress", "id": "O60729", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60729" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": 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] }, { "id": "Q5JU07", "url": "https://www.uniprot.org/uniprot/Q5JU07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5JU07-1", "url": "https://www.uniprot.org/uniprot/Q5JU07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTVILQSSVQSCKTSEPNISGSAGITKRTTRSASRKSSVKSLSISRTKTVLR", "length": 498, "header": "sp|O60729-1|CC14B_HUMAN Isoform 1 of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "isoforms": [ { "isoform_ac": "A0A9L9PY50-1", "url": "", "sequence": { "sequence": "MSREGAGAALVAEVIKDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTCPLAVLTSALCSVVIWWIVCDYILPILLFCLDGFRTQ", "length": 448, "header": "tr|A0A9L9PY50-1|CC14B_HUMAN Computationally mapped isoform of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96566816, "end_pos": 96515681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000481149.2", "url": "https://www.ensembl.org/id/ENST00000481149.2" }, { "database": "Ensembl Peptide", "id": "ENSP00000516645.1", "url": "https://www.ensembl.org/id/ENSP00000516645.1" } ] } }, { "isoform_ac": "H0Y577-1", "url": "", "sequence": { "sequence": "XMLWSHEPGGRGGSFGSRGDQRKEHCNFSISDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGST", "length": 268, "header": "tr|H0Y577-1|H0Y577_HUMAN Computationally mapped isoform of Cell division cycle 14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=8 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96566830, "end_pos": 96534001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000452280.5", "url": "https://www.ensembl.org/id/ENST00000452280.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000396951.1", "url": "https://www.ensembl.org/id/ENSP00000396951.1" } ] } }, { "isoform_ac": "H7C3U8-1", "url": "", "sequence": { "sequence": "ERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTCPLAVLTSALCSVVIWWIVCDYILPILLFCLDGFRTQ", "length": 480, "header": "tr|H7C3U8-1|CC14B_HUMAN Computationally mapped isoform of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96619363, "end_pos": 96515681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000412285.6", "url": "https://www.ensembl.org/id/ENST00000412285.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000413940.2", "url": "https://www.ensembl.org/id/ENSP00000413940.2" } ] } }, { "isoform_ac": "O60729-1", "url": "", "sequence": { "sequence": "MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTVILQSSVQSCKTSEPNISGSAGITKRTTRSASRKSSVKSLSISRTKTVLR", "length": 498, "header": "sp|O60729-1|CC14B_HUMAN Isoform 1 of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96619378, "end_pos": 96503756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000375241.6", "url": "https://www.ensembl.org/id/ENST00000375241.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000364389.1", "url": "https://www.ensembl.org/id/ENSP00000364389.1" } ] } }, { "isoform_ac": "O60729-2", "url": "", "sequence": { "sequence": "MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTLSISRTKTVLR", "length": 459, "header": "sp|O60729-2|CC14B_HUMAN Isoform 2 of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96619378, "end_pos": 96503756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000375240.7", "url": "https://www.ensembl.org/id/ENST00000375240.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000364388.3", "url": "https://www.ensembl.org/id/ENSP00000364388.3" } ] } }, { "isoform_ac": "O60729-3", "url": "", "sequence": { "sequence": "MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTDGWLSQAVTFLDRLLIWLGIHKD", "length": 471, "header": "sp|O60729-3|CC14B_HUMAN Isoform 3 of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96619378, "end_pos": 96496290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000474602.5", "url": "https://www.ensembl.org/id/ENST00000474602.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000417897.1", "url": "https://www.ensembl.org/id/ENSP00000417897.1" } ] } }, { "isoform_ac": "O60729-4", "url": "", "sequence": { "sequence": "MKRKSERRSSWAAAPPCSRRCSSTSPGVKKIRSSTQQDPRRRDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTCPLAVLTSALCSVVIWWIVCDYILPILLFCLDGFRTQ", "length": 485, "header": "sp|O60729-4|CC14B_HUMAN Isoform 4 of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96619378, "end_pos": 96515681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000463569.5", "url": "https://www.ensembl.org/id/ENST00000463569.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000420572.1", "url": "https://www.ensembl.org/id/ENSP00000420572.1" } ] } }, { "isoform_ac": "O60729-5", "url": "", "sequence": { "sequence": "MSREGAGAALVAEVIKDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPEPYSDDDEINGVTQGDRLRALKSRRQSKTNAIPLTVILQSSVQSCKTSEPNISGSAGITKRTTRSASRKSSVKSLSISRTKTVLR", "length": 461, "header": "sp|O60729-5|CC14B_HUMAN Isoform 5 of Dual specificity protein phosphatase CDC14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96566816, "end_pos": 96503756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000375242.7", "url": "https://www.ensembl.org/id/ENST00000375242.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000364390.3", "url": "https://www.ensembl.org/id/ENSP00000364390.3" } ] } }, { "isoform_ac": "Q5JU07-1", "url": "", "sequence": { "sequence": "APRRGLEKEGVTLVAFEPAGKTNVRVVTFEKSQPARADRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHS", "length": 228, "header": "tr|Q5JU07-1|Q5JU07_HUMAN Computationally mapped isoform of Cell division cycle 14B OS=Homo sapiens OX=9606 GN=CDC14B PE=1 SV=1 CANONICAL=O60729-1" }, "locus": { "chromosome": "9", "start_pos": 96618606, "end_pos": 96534141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000415608.1", "url": "https://www.ensembl.org/id/ENST00000415608.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000400480.1", "url": "https://www.ensembl.org/id/ENSP00000400480.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "p21-activated protein kinase: a crucial component of morphological signaling?", "journal": "Trends in biochemical sciences", "date": "1999", "authors": "Daniels RH, Bokoch GM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "10470034", "url": "https://glygen.org/publication/PubMed/10470034" } ] }, { "title": "Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch.", "journal": "Cell", "date": "2000", "authors": "Lei M, Lu W, Meng W, Parrini MC, Eck MJ, Mayer BJ, Harrison SC", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "10975528", "url": "https://glygen.org/publication/PubMed/10975528" } ] }, { "title": "Borg proteins control septin organization and are negatively regulated by Cdc42.", "journal": "Nature cell biology", "date": "2001", "authors": "Joberty G, Perlungher RR, Sheffield PJ, Kinoshita M, Noda M, Haystead T, Macara IG", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "11584266", "url": "https://glygen.org/publication/PubMed/11584266" } ] }, { "title": "Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1.", "journal": "Molecular cell", "date": "2002", "authors": "Parrini MC, Lei M, Harrison SC, Mayer BJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "11804587", "url": "https://glygen.org/publication/PubMed/11804587" } ] }, { "title": "Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation.", "journal": "Nat. Cell Biol.", "date": "2002", "authors": "Mailand N, Lukas C, Kaiser BK, Jackson PK, Bartek J, Lukas J", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "reference": [ { "type": "PubMed", "id": "11901424", "url": "https://glygen.org/publication/PubMed/11901424" } ] }, { "title": "Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.", "journal": "Mol. Biol. Cell", "date": "2002", "authors": "Kaiser BK, Zimmerman ZA, Charbonneau H, Jackson PK", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "reference": [ { "type": "PubMed", "id": "12134069", "url": "https://glygen.org/publication/PubMed/12134069" } ] }, { "title": "Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.", "journal": "Neuron", "date": "2003", "authors": "Penzes P, Beeser A, Chernoff J, Schiller MR, Eipper BA, Mains RE, Huganir RL", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "12546821", "url": "https://glygen.org/publication/PubMed/12546821" } ] }, { "title": "Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.", "journal": "Molecular and cellular biology", "date": "2003", "authors": "Coulombe P, Rodier G, Pelletier S, Pellerin J, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "12808096", "url": "https://glygen.org/publication/PubMed/12808096" } ] }, { "title": "The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase.", "journal": "EMBO J.", "date": "2003", "authors": "Gray Christopher H, Good Valerie M, Tonks Nicholas K, Barford David", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "reference": [ { "type": "PubMed", "id": "12853468", "url": "https://glygen.org/publication/PubMed/12853468" } ] }, { "title": "Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Julien C, Coulombe P, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "12915405", "url": "https://glygen.org/publication/PubMed/12915405" } ] }, { "title": "N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Coulombe P, Rodier G, Bonneil E, Thibault P, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "15226418", "url": "https://glygen.org/publication/PubMed/15226418" } ] }, { "title": "Scaffolding by ERK3 regulates MK5 in development.", "journal": "The EMBO journal", "date": "2004", "authors": "Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "15538386", "url": "https://glygen.org/publication/PubMed/15538386" } ] }, { "title": "Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway.", "journal": "The EMBO journal", "date": "2004", "authors": "Seternes OM, Mikalsen T, Johansen B, Michaelsen E, Armstrong CG, Morrice NA, Turgeon B, Meloche S, Moens U, Keyse SM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "15577943", "url": "https://glygen.org/publication/PubMed/15577943" } ] }, { "title": "Identification of extracellular signal-regulated kinase 3 as a new interaction partner of cyclin D3.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Sun M, Wei Y, Yao L, Xie J, Chen X, Wang H, Jiang J, Gu J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "16360641", "url": "https://glygen.org/publication/PubMed/16360641" } ] }, { "title": "Here come the septins: novel polymers that coordinate intracellular functions and organization.", "journal": "Journal of cell science", "date": "2006", "authors": "Spiliotis ET, Nelson WJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "16371649", "url": "https://glygen.org/publication/PubMed/16371649" } ] }, { "title": "Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Aberg E, Perander M, Johansen B, Julien C, Meloche S, Keyse SM, Seternes OM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "16971392", "url": "https://glygen.org/publication/PubMed/16971392" } ] }, { "title": "Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "16973613", "url": "https://glygen.org/publication/PubMed/16973613" } ] }, { "title": "Atypical mitogen-activated protein kinases: structure, regulation and functions.", "journal": "Biochimica et biophysica acta", "date": "2007", "authors": "Coulombe P, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "17161475", "url": "https://glygen.org/publication/PubMed/17161475" } ] }, { "title": "PRAK is essential for ras-induced senescence and tumor suppression.", "journal": "Cell", "date": "2007", "authors": "Sun P, Yoshizuka N, New L, Moser BA, Li Y, Liao R, Xie C, Chen J, Deng Q, Yamout M, Dong MQ, Frangou CG, Yates JR 3rd, Wright PE, Han J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "17254968", "url": "https://glygen.org/publication/PubMed/17254968" } ] }, { "title": "Endothelial cell migration during angiogenesis.", "journal": "Circulation research", "date": "2007", "authors": "Lamalice L, Le Boeuf F, Huot J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "17395884", "url": "https://glygen.org/publication/PubMed/17395884" } ] }, { "title": "Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "North BJ, Verdin E", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "reference": [ { "type": "PubMed", "id": "17488717", "url": "https://glygen.org/publication/PubMed/17488717" } ] }, { "title": "14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization.", "journal": "Cellular signalling", "date": "2007", "authors": "Tak H, Jang E, Kim SB, Park J, Suk J, Yoon YS, Ahn JK, Lee JH, Joe CO", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "17728103", "url": "https://glygen.org/publication/PubMed/17728103" } ] }, { "title": "Modulation of F-actin rearrangement by the cyclic AMP/cAMP-dependent protein kinase (PKA) pathway is mediated by MAPK-activated protein kinase 5 and requires PKA-induced nuclear export of MK5.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Gerits N, Mikalsen T, Kostenko S, Shiryaev A, Johannessen M, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "17947239", "url": "https://glygen.org/publication/PubMed/17947239" } ] }, { "title": "Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines.", "journal": "Neuron", "date": "2007", "authors": "Xie Z, Srivastava DP, Photowala H, Kai L, Cahill ME, Woolfrey KM, Shum CY, Surmeier DJ, Penzes P", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18031682", "url": "https://glygen.org/publication/PubMed/18031682" } ] }, { "title": "Proto-oncogene ACTR/AIB1 promotes cancer cell invasion by up-regulating specific matrix metalloproteinase expression.", "journal": "Cancer letters", "date": "2008", "authors": "Li LB, Louie MC, Chen HW, Zou JX", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18162290", "url": "https://glygen.org/publication/PubMed/18162290" } ] }, { "title": "A functional link between the human cell cycle-regulatory phosphatase Cdc14A and the atypical mitogen-activated kinase Erk3.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2008", "authors": "Hansen CA, Bartek J, Jensen S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18235225", "url": "https://glygen.org/publication/PubMed/18235225" } ] }, { "title": "The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5.", "journal": "The Biochemical journal", "date": "2008", "authors": "Perander M, Aberg E, Johansen B, Dreyer B, Guldvik IJ, Outzen H, Keyse SM, Seternes OM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18248330", "url": "https://glygen.org/publication/PubMed/18248330" } ] }, { "title": "Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression.", "journal": "Cancer research", "date": "2008", "authors": "Yan J, Erdem H, Li R, Cai Y, Ayala G, Ittmann M, Yu-Lee LY, Tsai SY, Tsai MJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18593949", "url": "https://glygen.org/publication/PubMed/18593949" } ] }, { "title": "The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.", "journal": "Molecular and cellular biology", "date": "2008", "authors": "Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18644862", "url": "https://glygen.org/publication/PubMed/18644862" } ] }, { "title": "The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.", "journal": "Cell", "date": "2008", "authors": "Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "reference": [ { "type": "PubMed", "id": "18662541", "url": "https://glygen.org/publication/PubMed/18662541" } ] }, { "title": "Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.", "journal": "Journal of cellular physiology", "date": "2008", "authors": "Deleris P, Rousseau J, Coulombe P, Rodier G, Tanguay PL, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "18720373", "url": "https://glygen.org/publication/PubMed/18720373" } ] }, { "title": "PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5.", "journal": "Cellular signalling", "date": "2009", "authors": "Kostenko S, Johannessen M, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "19166925", "url": "https://glygen.org/publication/PubMed/19166925" } ] }, { "title": "Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Aberg E, Torgersen KM, Johansen B, Keyse SM, Perander M, Seternes OM", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "19473979", "url": "https://glygen.org/publication/PubMed/19473979" } ] }, { "title": "Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements.", "journal": "Acta biochimica Polonica", "date": "2009", "authors": "Szczepanowska J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "19513348", "url": "https://glygen.org/publication/PubMed/19513348" } ] }, { "title": "Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology.", "journal": "Cellular and molecular life sciences : CMLS", "date": "2009", "authors": "Kostenko S, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "19593530", "url": "https://glygen.org/publication/PubMed/19593530" } ] }, { "title": "C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis.", "journal": "The Biochemical journal", "date": "2010", "authors": "Tanguay PL, Rodier G, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "20236090", "url": "https://glygen.org/publication/PubMed/20236090" } ] }, { "title": "HSPB1, actin filament dynamics, and aging cells.", "journal": "Annals of the New York Academy of Sciences", "date": "2010", "authors": "Doshi BM, Hightower LE, Lee J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "20536836", "url": "https://glygen.org/publication/PubMed/20536836" } ] }, { "title": "A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.", "journal": "Nature immunology", "date": "2010", "authors": "Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "20543837", "url": "https://glygen.org/publication/PubMed/20543837" } ] }, { "title": "Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function.", "journal": "Cellular and molecular life sciences : CMLS", "date": "2011", "authors": "Kostenko S, Shiryaev A, Gerits N, Dumitriu G, Klenow H, Johannessen M, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "20734105", "url": "https://glygen.org/publication/PubMed/20734105" } ] }, { "title": "Cross-talk between protein kinase A and the MAPK-activated protein kinases RSK1 and MK5.", "journal": "Journal of receptor and signal transduction research", "date": "2011", "authors": "Kostenko S, Shiryaev A, Dumitriu G, Gerits N, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "20849292", "url": "https://glygen.org/publication/PubMed/20849292" } ] }, { "title": "Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Deleris P, Trost M, Topisirovic I, Tanguay PL, Borden KL, Thibault P, Meloche S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "21177870", "url": "https://glygen.org/publication/PubMed/21177870" } ] }, { "title": "Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "De la Mota-Peynado A, Chernoff J, Beeser A", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "21317288", "url": "https://glygen.org/publication/PubMed/21317288" } ] }, { "title": "More, more, more: downregulation of a MK5-FoxO3a-mir34b/c pathway further increases c-Myc levels in colorectal cancer.", "journal": "Molecular cell", "date": "2011", "authors": "Myant K, Sansom OJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "21329875", "url": "https://glygen.org/publication/PubMed/21329875" } ] }, { "title": "The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis.", "journal": "Molecular cell", "date": "2011", "authors": "Kress TR, Cannell IG, Brenkman AB, Samans B, Gaestel M, Roepman P, Burgering BM, Bushell M, Rosenwald A, Eilers M", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "21329882", "url": "https://glygen.org/publication/PubMed/21329882" } ] }, { "title": "Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases.", "journal": "Microbiology and molecular biology reviews : MMBR", "date": "2011", "authors": "Cargnello M, Roux PP", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "21372320", "url": "https://glygen.org/publication/PubMed/21372320" } ] }, { "title": "A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.", "journal": "Nature immunology", "date": "2012", "authors": "Ochiai K, Maienschein-Cline M, Mandal M, Triggs JR, Bertolino E, Sciammas R, Dinner AR, Clark MR, Singh H", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "22267219", "url": "https://glygen.org/publication/PubMed/22267219" } ] }, { "title": "IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling.", "journal": "Genes & development", "date": "2012", "authors": "Stohr N, Kohn M, Lederer M, Glass M, Reinke C, Singer RH, Huttelmaier S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "22279049", "url": "https://glygen.org/publication/PubMed/22279049" } ] }, { "title": "ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.", "journal": "The Journal of clinical investigation", "date": "2012", "authors": "Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "22505454", "url": "https://glygen.org/publication/PubMed/22505454" } ] }, { "title": "The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology.", "journal": "Molecular and cellular biology", "date": "2012", "authors": "Brand F, Schumacher S, Kant S, Menon MB, Simon R, Turgeon B, Britsch S, Meloche S, Gaestel M, Kotlyarov A", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "22508986", "url": "https://glygen.org/publication/PubMed/22508986" } ] }, { "title": "Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5.", "journal": "Journal of molecular signaling", "date": "2012", "authors": "Kostenko S, Dumitriu G, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "22800433", "url": "https://glygen.org/publication/PubMed/22800433" } ] }, { "title": "Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?", "journal": "Cellular and molecular life sciences : CMLS", "date": "2013", "authors": "Bell JL, Wachter K, Muhleck B, Pazaitis N, Kohn M, Lederer M, Huttelmaier S", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "23069990", "url": "https://glygen.org/publication/PubMed/23069990" } ] }, { "title": "MK5 activates Rag transcription via Foxo1 in developing B cells.", "journal": "The Journal of experimental medicine", "date": "2013", "authors": "Chow KT, Timblin GA, McWhirter SM, Schlissel MS", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "23878308", "url": "https://glygen.org/publication/PubMed/23878308" } ] }, { "title": "Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK).", "journal": "The international journal of biochemistry & cell biology", "date": "2014", "authors": "Kostenko S, Jensen KL, Moens U", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "24309468", "url": "https://glygen.org/publication/PubMed/24309468" } ] }, { "title": "ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression.", "journal": "Journal of cellular physiology", "date": "2014", "authors": "Wang W, Bian K, Vallabhaneni S, Zhang B, Wu RC, O'Malley BW, Long W", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "24585635", "url": "https://glygen.org/publication/PubMed/24585635" } ] }, { "title": "Heat shock protein 27 phosphorylation state is associated with cancer progression.", "journal": "Frontiers in genetics", "date": "2014", "authors": "Katsogiannou M, Andrieu C, Rocchi P", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "25339975", "url": "https://glygen.org/publication/PubMed/25339975" } ] 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prognosticator for triple-negative breast cancer.", "journal": "Mathematical biosciences and engineering : MBE", "date": "2020", "authors": "Li JD, Chen G, Wu M, Huang Y, Tang W", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" } ], "reference": [ { "type": "PubMed", "id": "33378938", "url": "https://glygen.org/publication/PubMed/33378938" } ] }, { "title": "CDC14B is a favorable biomarker for recurrence and prognosis of GBM.", "journal": "Clinical neurology and neurosurgery", "date": "2023-04", "authors": "Zhu Chao, Zhao Yang, Zheng Wei", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" } ], "reference": [ { "type": "PubMed", "id": "36898299", "url": "https://glygen.org/publication/PubMed/36898299" } ] }, { "title": "The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans.", "journal": "The EMBO journal", "date": "2023-08-15", "authors": "Partscht Patrick, Schiebel Elmar", "evidence": [ { "database": "RefSeq", "id": "NP_001070649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070649" } ], "reference": [ { "type": "PubMed", "id": "37493185", "url": "https://glygen.org/publication/PubMed/37493185" } ] }, { "title": "Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Manser E, Chong C, Zhao ZS, Leung T, Michael G, Hall C, Lim L", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "7559638", "url": "https://glygen.org/publication/PubMed/7559638" } ] }, { "title": "Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27.", "journal": "Molecular and cellular biology", "date": "1995", "authors": "Lavoie JN, Lambert H, Hickey E, Weber LA, Landry J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "7799959", "url": "https://glygen.org/publication/PubMed/7799959" } ] }, { "title": "A brain serine/threonine protein kinase activated by Cdc42 and Rac1.", "journal": "Nature", "date": "1994", "authors": "Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "8107774", "url": "https://glygen.org/publication/PubMed/8107774" } ] }, { "title": "A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast.", "journal": "The Journal of biological chemistry", "date": "1997-11-21", "authors": "Li L, Ernsting B R, Wishart M J, Lohse D L, Dixon J E", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "reference": [ { "type": "PubMed", "id": "9367992", "url": "https://glygen.org/publication/PubMed/9367992" } ] }, { "title": "Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Zhang B, Chernoff J, Zheng Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "9535855", "url": "https://glygen.org/publication/PubMed/9535855" } ] }, { "title": "PRAK, a novel protein kinase regulated by the p38 MAP kinase.", "journal": "The EMBO journal", "date": "1998", "authors": "New L, Jiang Y, Zhao M, Liu K, Zhu W, Flood LJ, Kato Y, Parry GC, Han J", "evidence": [ { "database": "Reactome", "id": "R-HSA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5687128" } ], "reference": [ { "type": "PubMed", "id": "9628874", "url": "https://glygen.org/publication/PubMed/9628874" } ] }, { "title": "Cyclin D3: requirement for G1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation.", 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"go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "membrane-bounded organelle", "id": "GO:0043227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043227", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "intracellular non-membrane-bounded organelle", "id": "GO:0043232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043232", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O60729", "url": "https://www.uniprot.org/uniprot/O60729" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": 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"D3ZNK9-1", "D4ADT2-1", "D4A3W6-1", "D3ZBG7-1", "P20646-1", "A0A8I6G7Q4-1", "A6HQ12-1", "A0A8I6AJQ7-1", "A0A8I6B5G4-1", "A0A8I5Y1B8-1", "Q9UMZ3-1", "P18031-1", "Q99502-1", "O75061-1", "Q9UNH5-1", "A4D256-1", "O60729-1", "Q16667-1", "P51452-1", "Q9BV47-1", "Q99504-1", "O95677-1", "Q9H596-1", "O00167-1", "Q6B8I1-1", "Q9NRW4-1", "Q16828-1", "Q4G0W2-1", "Q99956-1", "Q8NEJ0-1", "O95147-1", "P28562-1", "Q9BVJ7-1", "Q9H1R2-1", "Q9UII6-1", "Q16690-1", "Q13115-1", "Q9UNI6-1", "Q9BY84-1", "Q9Y6W6-1", "Q05923-1", "B3EWF7-1", "Q68J44-1", "Q16829-1", "Q8WTR2-1", "Q13202-1", "P30307-1", "P30304-1", "Q86V88-1", "P30305-1", "Q9NYA4-1", "Q13615-1", "Q15678-1", "Q9Y2R2-1", "Q15256-1", "Q16827-1", "Q06124-2", "Q15262-1", "Q4JDL3-1", "P54829-1", "O14522-3", "P28827-1", "P35236-1", "Q99952-1", "P29350-1", "Q12913-1", "P23467-1", "P08575-3", "P18433-5", "Q9HD43-1", "P23470-1", "Q92932-1", "A6NDG6-1", "Q8WUK0-1", "P43378-1", "P23468-1", "Q16825-1", "Q9H3S7-1", "P29074-1", "P17706-1", "P26045-1", "P10586-1", 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"O55082-1", "P18052-1", "Q6PB44-1", "Q64512-1", "P06800-4", "P0C5E4-1", "P35235-2", "P80560-1", "Q05909-1", "Q06180-1", "Q61152-1", "Q5SW75-1", "Q64455-1", "Q66GT5-1", "Q76I79-1", "Q99M80-1", "P70289-1", "O08586-1", "Q7TNL7-1", "Q1HL35-1", "Q8CE08-1", "Q8CGB6-1", "P25044-1", "Q00684-1", "P29461-1", "P23748-1", "P38148-1", "P50946-1", "P38590-1", "P40048-1", "P40347-1", "P40479-1", "Q02256-1", "P40081-1", "Q12454-1", "Q54T76-1", "Q1ZXG8-1", "Q54DU9-1", "Q54R42-1", "Q55BI8-1", "Q55CS8-1", "Q55E39-1", "Q55GW2-1", "Q86IL4-1", "P34137-1", "P34138-1", "P54637-1", "Q54QM6-1", "Q54Y32-1", "Q556Y8-1", "Q55CS7-1", "Q8T9S7-1", "P82890-1", "P35832-1", "P29349-1", "P35992-5", "Q6NN85-1", "Q86BN8-1", "Q7KMQ6-1", "P82891-1", "A1ZAB3-1", "P16621-1", "O61722-1", "Q9W0G1-1", "Q03019-1", "P20483-1", "X2JEB8-1", "Q9VVW5-1", "Q05201-1", "P16620-1", "Q9VWF4-1", "Q9W4F5-1", "Q9W0R3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "20629", "name": "", "equation": "H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q4KLK9-1", "P62142-1", "Q3SWT6-1", "Q5I0E6-1", "Q5FWT7-1", "Q3B7T6-1", "B4F7B7-1", "Q5FVI9-1", "P63329-1", "P20651-1", "Q66H71-1", "Q80Z30-1", "Q91XQ2-1", "B2RZ50-1", "P63088-1", "Q64346-1", "P0C595-1", "Q6AXW7-1", "Q62767-1", "Q63340-1", "O54838-1", "Q64623-1", "Q9JIM4-1", "P63331-1", "O54857-1", "Q9Z1Z6-1", "F1LNI5-1", "Q562B5-1", "Q641Y6-1", "P20650-1", "P35815-1", "P62138-1", "Q5BJ92-1", "Q5M821-1", "Q5XIS1-1", "Q9WTR8-1", "Q9WVR7-1", "Q64620-1", "P53042-1", "P62716-1", "P0C089-1", "A0A8I6AF61-1", "A0A0G2K9N1-1", "D4A520-1", "A0A0G2K0J7-1", "D3ZNK9-1", "D3ZP99-1", "D4A3W6-1", "E2CWF0-1", "D3ZN69-1", "Q2YDV1-1", "M0R5X1-1", "D3ZBG7-1", "B1WC24-1", "Q8VD52-1", "M0R4W4-1", "A6HQ12-1", "A0A8I5ZU99-1", "A6K136-1", "Q8NI37-1", "P36873-1", "Q9Y5B0-1", "P62140-1", "Q9UNH5-1", "A4D256-1", "O60729-1", "Q16667-1", "P51452-1", "O95476-1", "O14595-1", "O15194-1", "Q9BV47-1", "P62136-1", "Q9BVJ7-1", "Q9H1R2-1", "Q9BY84-1", "Q9NRW4-1", "Q16828-1", "Q9H596-1", "Q13202-1", "Q4G0W2-1", "Q99956-1", "Q8NEJ0-1", "Q6B8I1-1", "B3EWF7-1", "P28562-1", "Q16690-1", "Q13115-1", "Q9GZU7-1", "Q9UNI6-1", "Q9Y6W6-1", "Q68J44-1", "Q16829-1", "Q8WTR2-1", "Q9BRF8-1", "O95147-1", "Q9UII6-1", "Q9H0C8-1", "Q99502-1", "Q9ULR3-1", "P60510-1", "P49593-1", "O15297-1", "Q5SGD2-1", "O15355-1", "Q8WY54-2", "Q8N819-1", "Q5JR12-1", "O75688-1", "O14830-1", "O14829-1", "P16298-1", "Q8IXW5-1", "O60346-1", "Q6ZVD8-1", "P67775-1", "P48454-1", "P53041-1", "O00743-1", "Q96MI6-5", "Q8WUK0-1", "P35813-1", "P62714-1", "Q96HS1-1", "Q08209-1", "P60484-1", "Q8N3J5-1", "Q8TE77-1", "Q76I76-1", "Q8WVY7-1", "Q9NP77-1", "Q8WYL5-1", "Q96GD0-1", "A0A1W2PQ27-1", "A0A1W2PR75-1", "A0A1W2PQC6-1", "A0A1W2PQD8-1", "A0A1W2PQJ5-1", "A0A1W2PQ64-1", "Q92562-1", "P63087-1", "Q9D7X3-1", "Q6PFY9-1", "Q3TP92-1", "P58465-1", "P58466-1", "Q7TSG2-1", "Q8BFS6-1", "Q6GQT0-1", "Q810P3-1", "Q8R4V2-1", "Q99N11-1", "Q9JLY7-1", "Q9WUA5-1", "O09112-1", "Q8BTR5-1", "Q9DBB1-1", "Q9D700-1", "Q8BX07-1", "Q9QYJ7-1", "Q8VE01-1", "Q91Z46-1", "P28563-1", "Q8K4T5-1", "Q6NT99-1", "Q8BK84-1", "Q8BFV3-1", "P97767-1", "Q9D0T2-1", "Q9D9D8-1", "Q9ESS0-1", "Q8R0F6-1", "Q149T7-1", "Q3UYC0-1", "P62141-1", "O35385-1", "Q8BX10-1", "Q6NVE9-1", "Q8BU27-3", "Q80TL0-1", "Q8BGL1-1", "Q8BHN0-1", "Q8CGA0-1", "Q9QZ67-1", "O35655-1", "P97470-1", "Q8BXA7-1", "Q8CHE4-1", "P49443-1", "Q61074-1", "Q5SW75-1", "P62715-1", "P63328-1", "Q8K330-1", "Q9CY97-1", "P62137-1", "P36993-1", "P48453-1", "P48455-1", "Q60676-1", "Q66GT5-1", "Q76I79-1", "Q9CQR6-1", "Q8VC34-1", "P63330-1", "O08586-1", "Q8BXN7-1", "Q8BGR9-1", "P60487-1", "Q91WF7-1", "P14747-1", "P20604-1", "P23594-1", "P23595-1", "P25646-1", "P26570-1", "P32598-1", "P33329-1", "P38757-1", "P38797-1", "P23287-1", "P53043-1", "P32345-1", "P32838-1", "P32945-1", "P38148-1", "P39966-1", "P40084-1", "P53538-1", "P34221-1", "P35182-1", "P38089-1", "Q03254-1", "Q12378-1", "Q54GL8-1", "Q54IJ8-1", "Q54M72-1", "Q54M73-1", "Q54QE5-1", "Q558Z3-1", "Q54R42-1", "Q55E39-1", "Q54T01-1", "Q54T76-1", "Q54WS9-1", "Q556S4-1", "Q55BI8-1", "Q55CS8-1", "Q8ST13-1", "Q9U9A3-1", "Q75JA4-1", "O15757-1", "O15743-1", "Q54RD6-1", "Q54Y32-1", "Q556Y8-1", "Q55CS7-1", "Q7YSW8-1", "Q9XYL0-1", "Q9XZE5-1", "Q9Y0B7-1", "Q8T9S7-1", "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q86BN8-1", "Q9VJ07-1", "P12982-1", "P48462-1", "M9PFN0-1", "O46084-1", "Q9VRG7-1", "P23696-1", "Q27889-1", "Q9VXF1-1", "X2JEB8-1", "A8QI94-1", "P48456-1", "Q9VWE4-1", "Q9VVW5-1", "Q9VWF4-1", "Q7KVM5-1", "Q9XZ16-1", "Q9VQL9-1", "Q9W0E2-1", "Q9W3R1-1", "Q5LJN2-1", "Q9W2A5-1", "Q9W147-1", "Q7KMQ6-1", "Q961C5-1", "Q9W173-1", "M9PI51-1", "Q9VZS0-1", "Q7JY68-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P62142-1", "Q3SWT6-1", "Q4KLK9-1", "Q5I0E6-1", "P20651-1", "Q5FWT7-1", "A0A0G2JYA4-1", "Q3B7T6-1", "B4F7B7-1", "Q5FVI9-1", "P63329-1", "Q66H71-1", "Q80Z30-1", "Q91XQ2-1", "B2RZ50-1", "P63088-1", "Q64346-1", "P0C595-1", "Q6AXW7-1", "Q62767-1", "Q63340-1", "O54838-1", "Q64623-1", "Q9JIM4-1", "P63331-1", "O54857-1", "Q9Z1Z6-1", "Q9WVR7-1", "F1LNI5-1", "P20650-1", "P35815-1", "P62138-1", "Q562B5-1", "Q5BJ92-1", "Q5M821-1", "Q5XIS1-1", "Q641Y6-1", "Q9WTR8-1", "Q64620-1", "P53042-1", "P62716-1", "P0C089-1", "A0A8I6AF61-1", "A0A0G2K9N1-1", "Q2YDV1-1", "E2CWF0-1", "D4A520-1", "D3ZN69-1", "A0A0G2K0J7-1", "D3ZNK9-1", "D4A3W6-1", "F1M4Q5-1", "M0R5X1-1", "A0A8I6B0P9-1", "D3ZBG7-1", "B1WC24-1", "M0R4W4-1", "A6HQ12-1", "A0A8I5ZU99-1", "Q8NI37-1", "P36873-1", "P60510-1", "Q16667-1", "Q9Y5B0-1", "P48454-1", "Q08209-1", "P53041-1", "P62140-1", "P62714-1", "Q9UNH5-1", "A4D256-1", "O60729-1", "P51452-1", "O95476-1", "O14595-1", "O15194-1", "O14829-1", "Q9BV47-1", "P62136-1", "O95147-1", "Q9BVJ7-1", "Q9H1R2-1", "Q9BY84-1", "Q9NRW4-1", "Q16828-1", "Q9H596-1", "Q13202-1", "Q4G0W2-1", "Q99956-1", "Q8NEJ0-1", "Q6B8I1-1", "B3EWF7-1", "P28562-1", "Q16690-1", "Q13115-1", "Q9GZU7-1", "Q9UNI6-1", "Q9Y6W6-1", "Q05923-1", "Q68J44-1", "Q16829-1", "Q8WTR2-1", "Q9BRF8-1", "Q9UII6-1", "Q9H0C8-1", "Q99502-1", "Q9ULR3-1", "P49593-1", "O15297-1", "Q5SGD2-1", "O15355-1", "Q8IXW5-1", "Q8WY54-2", "Q8N819-1", "Q5JR12-1", "O75688-1", "O14830-1", "O60346-1", "Q6ZVD8-1", "P67775-1", "P16298-1", "O00743-1", "Q96MI6-5", "Q8WUK0-1", "P35813-1", "Q96HS1-1", "P60484-1", "Q8TE77-1", "Q76I76-1", "Q8WYL5-1", "Q8WVY7-1", "Q9NP77-1", "A0A1W2PQ27-1", "A0A1W2PR75-1", "A0A1W2PQC6-1", "A0A1W2PQD8-1", "A0A1W2PQJ5-1", "A0A1W2PQ64-1", "P63087-1", "P48453-1", "Q9D7X3-1", "O35655-1", "Q9CQR6-1", "Q6PFY9-1", "Q3TP92-1", "P58465-1", "P58466-1", "Q7TSG2-1", "Q8BFS6-1", "Q6GQT0-1", "Q810P3-1", "Q8R4V2-1", "Q99N11-1", "Q9JLY7-1", "Q9WUA5-1", "O09112-1", "Q8BTR5-1", "Q9DBB1-1", "Q9D700-1", "Q8BX07-1", "Q9QYJ7-1", "Q8VE01-1", "Q91Z46-1", "P28563-1", "Q8K4T5-1", "Q6NT99-1", "Q8BK84-1", "Q8BFV3-1", "Q05922-1", "P97767-1", "Q9D0T2-1", "Q9D9D8-1", "Q9ESS0-1", "Q8R0F6-1", "Q149T7-1", "Q3UYC0-1", "P62141-1", "O35385-1", "Q8BX10-1", "Q6NVE9-1", "Q8BU27-3", "Q80TL0-1", "Q8BGL1-1", "Q8BHN0-1", "Q8CGA0-1", "Q9QZ67-1", "Q76I79-1", "P97470-1", "Q8BXA7-1", "Q8CHE4-1", "P49443-1", "Q61074-1", "Q5SW75-1", "P62715-1", "P63328-1", "Q8VC34-1", "Q8K330-1", "Q9CY97-1", "P62137-1", "P36993-1", "P48455-1", "Q60676-1", "Q66GT5-1", "P63330-1", "O08586-1", "Q7TNL7-1", "Q8BGR9-1", "Q1HL35-1", "P14747-1", "P20604-1", "P23594-1", "P23595-1", "P25646-1", "P26570-1", "P32598-1", "P33329-1", "P38757-1", "P38797-1", "P23287-1", "P53043-1", "P32345-1", "P32838-1", "P32945-1", "P38148-1", "P39966-1", "P40084-1", "P53538-1", "P34221-1", "P35182-1", "P38089-1", "Q03254-1", "Q12378-1", "Q54GL8-1", "Q54IJ8-1", "Q54M72-1", "Q54M73-1", "Q54QE5-1", "Q558Z3-1", "Q54R42-1", "Q54T01-1", "Q54T76-1", "Q54WS9-1", "Q556S4-1", "Q55BI8-1", "Q55CS8-1", "Q55E39-1", "Q8ST13-1", "Q9U9A3-1", "Q75JA4-1", "O15743-1", "O15757-1", "Q54RD6-1", "Q54Y32-1", "Q556Y8-1", "Q55CS7-1", "Q7YSW8-1", "Q9XYL0-1", "Q9XZE5-1", "Q9Y0B7-1", "Q8T9S7-1", "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q9VJ07-1", "P12982-1", "P48462-1", "Q86BN8-1", "O46084-1", "Q9VRG7-1", "P23696-1", "Q27889-1", "Q9VXF1-1", "X2JEB8-1", "A8QI94-1", "Q9VVW5-1", "P48456-1", "Q9VWE4-1", "Q9VWF4-1", "Q7KVM5-1", "Q9XZ16-1", "Q95TV5-1", "Q9VQL9-1", "Q9W0E2-1", "Q9W3R1-1", "Q5LJN2-1", "Q9W2A5-1", "Q9W147-1", "Q7KMQ6-1", "Q961C5-1", "Q9W173-1", "M9PI51-1", "Q9VZS0-1", "Q7JY68-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] }, { "id": "R-HSA-5692749", "name": "CDC14A,B bind MAPK6", "equation": "", "summary": "The phosphatases CDC14A and CDC14B bind directly to MAPK6 as assessed by yeast two hybrid and by co-immunoprecipitation (Tanguay et al, 2010; Hansen et al, 2008). CDC14 phosphatases are able to reverse the CDK1-dependent phosphorylation of MAPK6 in vitro, and overexpression of WT but not catalytically inactive forms of CDC14A or B in vivo leads to dephosphorylation of T698 (Hansen et al, 2008; Tanguay et al, 2010). These results suggest that CDC14 phosphatases reverse the CDK1-dependent phosphorylation of MAPK6 during mitosis. These reactions are depicted as occuring in the nucleoplasm, but the site of action has not been determined, and CDC14 and MAPK6 colocalize throughout the cell (Hansen et al, 2008).", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O60729-1", "Q9UNH5-1", "Q16659-1" ], "evidence": [ { "id": "R-HSA-5692749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5692749" } ] }, { "id": "R-HSA-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "equation": "", "summary": "CDC14A and B bind to MAPK6 and antagonize the CDK1-dependent phosphorylation of the C-terminal extension during mitosis (Tanguay et al, 2010; Hansen et al, 2008).", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O60729-1", "Q9UNH5-1", "Q16659-1" ], "evidence": [ { "id": "R-HSA-5692754", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5692754" } ] }, { "id": "R-HSA-5692764", "name": "MAPK6 binds CCND3", "equation": "", "summary": "MAPK6 interacts with Cyclin D3 (CCND3) through its C-terminal extension, and this interaction is stabilized by overexpression of CDC14 phosphatase (Sun et al, 2006; Hansen et al, 2008). Although the physiological relevance of the interaction between MAPK6 and CCND3 is not known, both proteins regulate cell cycle entry and MAPK6 is stabilized during differentiation and upon inhibition of proliferation (Coulombe et al, 2003; Bartkova et al, 1998; Julien et al, 2003).", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O60729-1", "Q9UNH5-1", "Q16659-1" ], "evidence": [ { "id": "R-HSA-5692764", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5692764" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0G2JYA4", "gene_name": "LOC100362453", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2JYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JYA4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2JYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JYA4" } ] } ] }, { "uniprot_ac": "A0A0G2JZ01", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2JZ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ01" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2JZ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZ01" } ] } ] }, { "uniprot_ac": "A0A0G2K0J7", "gene_name": "Ctdp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K0J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K0J7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2K0J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K0J7" } ] } ] }, { "uniprot_ac": "A0A0G2K1T5", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K1T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K1T5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K1T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K1T5" } ] } ] }, { "uniprot_ac": "A0A0G2K2N0", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2N0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2N0" } ] } ] }, { "uniprot_ac": "A0A0G2K3H0", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K3H0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K3H0" } ] } ] }, { "uniprot_ac": "A0A0G2K8V0", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K8V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K8V0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K8V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K8V0" } ] } ] }, { "uniprot_ac": "A0A0G2K9N1", "gene_name": "Dusp13b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] } ] }, { "uniprot_ac": "A0A1W2PQ27", "gene_name": "SSU72L1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZU99" } ] } ] }, { "uniprot_ac": "A0A8I5ZV35", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I5ZV35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV35" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I5ZV35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV35" } ] } ] }, { "uniprot_ac": "A0A8I5ZW41", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I5ZW41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW41" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I5ZW41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW41" } ] } ] }, { "uniprot_ac": "A0A8I6A1V1", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6A1V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1V1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6A1V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1V1" } ] } ] }, { "uniprot_ac": "A0A8I6AF61", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] } ] }, { "uniprot_ac": "A0A8I6AJQ7", "gene_name": "ENSRNOG00000069024", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJQ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6AJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJQ7" } ] } ] }, { "uniprot_ac": "A0A8I6B0P9", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6B0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B0P9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8I6B0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B0P9" } ] } ] }, { "uniprot_ac": "A0A8I6B402", "gene_name": "Eya4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6B402", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B402" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6B402", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B402" } ] } ] }, { "uniprot_ac": "A0A8I6B5G4", "gene_name": "RGD1566035", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6B5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B5G4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6B5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B5G4" } ] } ] }, { "uniprot_ac": "A0A8I6G7Q4", "gene_name": "AABR07036974.1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6G7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G7Q4" } ] } ] }, { "uniprot_ac": "A0A8I6GK94", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6GK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK94" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6GK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK94" } ] } ] }, { "uniprot_ac": "A1L1L3", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A1L1L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1L1L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A1L1L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1L1L3" } ] } ] }, { "uniprot_ac": "A1ZAB3", "gene_name": "Ptp52F", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A1ZAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZAB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A1ZAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZAB3" } ] } ] }, { "uniprot_ac": "A2A8L5", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2A8L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2A8L5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2A8L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2A8L5" } ] } ] }, { "uniprot_ac": "A2ALK8", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2ALK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ALK8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2ALK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ALK8" } ] } ] }, { "uniprot_ac": "A4D256", "gene_name": "CDC14C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] } ] }, { "uniprot_ac": "A6HQ12", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] } ] }, { "uniprot_ac": "A6K136", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6K136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K136" } ] }, { "ec_number": "3.1.3.52", "activity": "H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A6K136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K136" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6K136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K136" } ] } ] }, { "uniprot_ac": "A6NDG6", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "A6NDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6NDG6" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6NDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6NDG6" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A6NDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6NDG6" } ] } ] }, { "uniprot_ac": "A8DYY5", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8DYY5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8DYY5" } ] } ] }, { "uniprot_ac": "A8QI94", "gene_name": "Pp1-Y1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A8QI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8QI94" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A8QI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8QI94" } ] } ] }, { "uniprot_ac": "B0V2N1", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B0V2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0V2N1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B0V2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0V2N1" } ] } ] }, { "uniprot_ac": "B1AUH1", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B1AUH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1AUH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B1AUH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1AUH1" } ] } ] }, { "uniprot_ac": "B1WC24", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B1WC24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WC24" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B1WC24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WC24" } ] } ] }, { "uniprot_ac": "B2GV87", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2GV87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GV87" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2GV87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GV87" } ] } ] }, { "uniprot_ac": "B2RU80", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2RU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RU80" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2RU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RU80" } ] } ] }, { "uniprot_ac": "B2RZ50", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] } ] }, { "uniprot_ac": "B3EWF7", "gene_name": "EPM2A", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] } ] }, { "uniprot_ac": "B4F7B7", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] } ] }, { "uniprot_ac": "B9EKR1", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B9EKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B9EKR1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B9EKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B9EKR1" } ] } ] }, { "uniprot_ac": "D3ZBG7", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBG7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBG7" } ] } ] }, { "uniprot_ac": "D3ZDK7", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "D3ZDK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDK7" } ] } ] }, { "uniprot_ac": "D3ZN69", "gene_name": "Ppef2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZN69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZN69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZN69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZN69" } ] } ] }, { "uniprot_ac": "D3ZNK9", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZNK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZNK9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZNK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZNK9" } ] } ] }, { "uniprot_ac": "D3ZP99", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP99" } ] } ] }, { "uniprot_ac": "D3ZVI5", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZVI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVI5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "D3ZVI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVI5" } ] } ] }, { "uniprot_ac": "D4A3W6", "gene_name": "Dusp16", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D4A3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3W6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D4A3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3W6" } ] } ] }, { "uniprot_ac": "D4A520", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D4A520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A520" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D4A520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A520" } ] } ] }, { "uniprot_ac": "D4ADT2", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "D4ADT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "D4ADT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT2" } ] } ] }, { "uniprot_ac": "E2CWF0", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E2CWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E2CWF0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E2CWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E2CWF0" } ] } ] }, { "uniprot_ac": "E9Q0N2", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E9Q0N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q0N2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E9Q0N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q0N2" } ] } ] }, { "uniprot_ac": "E9Q612", "gene_name": "Ptpro", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E9Q612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q612" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E9Q612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q612" } ] } ] }, { "uniprot_ac": "F1LNI5", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1LNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNI5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1LNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNI5" } ] } ] }, { "uniprot_ac": "F1LP13", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1LP13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP13" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1LP13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP13" } ] } ] }, { "uniprot_ac": "F1LQQ5", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1LQQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LQQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1LQQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LQQ5" } ] } ] }, { "uniprot_ac": "F1M4Q5", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1M4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M4Q5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1M4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M4Q5" } ] } ] }, { "uniprot_ac": "G3V6B9", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3V6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6B9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3V6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6B9" } ] } ] }, { "uniprot_ac": "G3V7Q4", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3V7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V7Q4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3V7Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V7Q4" } ] } ] }, { "uniprot_ac": "G3V9S3", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3V9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V9S3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3V9S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V9S3" } ] } ] }, { "uniprot_ac": "M0R4W4", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M0R4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R4W4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M0R4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R4W4" } ] } ] }, { "uniprot_ac": "M0R5X1", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M0R5X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R5X1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M0R5X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R5X1" } ] } ] }, { "uniprot_ac": "M9PFN0", "gene_name": "hzg", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PFN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PFN0" } ] } ] }, { "uniprot_ac": "M9PI51", "gene_name": "Dmel\\CG10089", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI51" } ] } ] }, { "uniprot_ac": "O00167", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O00167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00167" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O00167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00167" } ] } ] }, { "uniprot_ac": "O00743", "gene_name": "PPP6C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O00743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00743" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O00743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00743" } ] } ] }, { "uniprot_ac": "O08575", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08575" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08575" } ] } ] }, { "uniprot_ac": "O08586", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] } ] }, { "uniprot_ac": "O08617", "gene_name": "Ptprr", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08617" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08617" } ] } ] }, { "uniprot_ac": "O09112", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] } ] }, { "uniprot_ac": "O14522", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O14522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14522" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O14522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14522" } ] } ] }, { "uniprot_ac": "O14595", "gene_name": "CTDSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O14595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O14595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14595" } ] } ] }, { "uniprot_ac": "O14829", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O14829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O14829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14829" } ] } ] }, { "uniprot_ac": "O14830", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O14830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O14830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14830" } ] } ] }, { "uniprot_ac": "O15194", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15194", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15194" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15194", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15194" } ] } ] }, { "uniprot_ac": "O15297", "gene_name": "PPM1D", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15297", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15297" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15297", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15297" } ] } ] }, { "uniprot_ac": "O15355", "gene_name": "PPM1G", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15355" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15355" } ] } ] }, { "uniprot_ac": "O15743", "gene_name": "spnA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15743" } ] } ] }, { "uniprot_ac": "O15757", "gene_name": "pppB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15757" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15757" } ] } ] }, { "uniprot_ac": "O35239", "gene_name": "Ptpn9", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O35239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35239" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O35239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35239" } ] } ] }, { "uniprot_ac": "O35385", "gene_name": "Ppef2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O35385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35385" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O35385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35385" } ] } ] }, { "uniprot_ac": "O35655", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O35655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35655" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O35655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35655" } ] } ] }, { "uniprot_ac": "O46084", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O46084" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O46084" } ] } ] }, { "uniprot_ac": "O54838", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] } ] }, { "uniprot_ac": "O54857", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] } ] }, { "uniprot_ac": "O55082", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O55082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55082" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O55082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55082" } ] } ] }, { "uniprot_ac": "O60346", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O60346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60346" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O60346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60346" } ] } ] }, { "uniprot_ac": "O60729", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] } ] }, { "uniprot_ac": "O61722", "gene_name": "PRL-1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61722" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61722" } ] } ] }, { "uniprot_ac": "O70274", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O70274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70274" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O70274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70274" } ] } ] }, { "uniprot_ac": "O75061", "gene_name": "DNAJC6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O75061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75061" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O75061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75061" } ] } ] }, { "uniprot_ac": "O75365", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O75365", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75365" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O75365", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75365" } ] } ] }, { "uniprot_ac": "O75688", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O75688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75688" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O75688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75688" } ] } ] }, { "uniprot_ac": "O76932", "gene_name": "Pp4-19C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76932" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76932" } ] } ] }, { "uniprot_ac": "O88488", "gene_name": "Ptprq", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O88488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88488" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O88488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88488" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O88488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88488" } ] } ] }, { "uniprot_ac": "O88902", "gene_name": "Ptpn23", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O88902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88902" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O88902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88902" } ] } ] }, { "uniprot_ac": "O95147", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] } ] }, { "uniprot_ac": "O95476", "gene_name": "CTDNEP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O95476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95476" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O95476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95476" } ] } ] }, { "uniprot_ac": "O95677", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O95677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95677" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O95677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95677" } ] } ] }, { "uniprot_ac": "P04157", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P04157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04157" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P04157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04157" } ] } ] }, { "uniprot_ac": "P06800", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P06800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06800" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P06800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06800" } ] } ] }, { "uniprot_ac": "P08575", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08575" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P08575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08575" } ] } ] }, { "uniprot_ac": "P0C089", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] } ] }, { "uniprot_ac": "P0C595", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] } ] }, { "uniprot_ac": "P0C5E4", "gene_name": "Ptprq", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P0C5E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5E4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C5E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5E4" } ] } ] }, { "uniprot_ac": "P10586", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P10586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10586" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P10586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10586" } ] } ] }, { "uniprot_ac": "P11612", "gene_name": "PpY-55A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11612" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11612" } ] } ] }, { "uniprot_ac": "P12982", "gene_name": "Pp1-87B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12982" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12982" } ] } ] }, { "uniprot_ac": "P14747", "gene_name": "CMP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P14747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14747" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P14747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14747" } ] } ] }, { "uniprot_ac": "P15309", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P15309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15309" } ] } ] }, { "uniprot_ac": "P16298", "gene_name": "PPP3CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P16298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16298" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P16298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16298" } ] } ] }, { "uniprot_ac": "P16620", "gene_name": "Ptp69D", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P16620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16620" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P16620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16620" } ] } ] }, { "uniprot_ac": "P16621", "gene_name": "Lar", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P16621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16621" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P16621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16621" } ] } ] }, { "uniprot_ac": "P17706", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P17706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17706" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P17706", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17706" } ] } ] }, { "uniprot_ac": "P18031", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P18031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18031" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P18031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18031" } ] } ] }, { "uniprot_ac": "P18052", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P18052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18052" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P18052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18052" } ] } ] }, { "uniprot_ac": "P18433", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P18433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18433" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P18433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18433" } ] } ] }, { "uniprot_ac": "P20417", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20417" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P20417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20417" } ] } ] }, { "uniprot_ac": "P20483", "gene_name": "stg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20483" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P20483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20483" } ] } ] }, { "uniprot_ac": "P20604", "gene_name": "SIT4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P20604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20604" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P20604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20604" } ] } ] }, { "uniprot_ac": "P20646", "gene_name": "Acp3", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] }, { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20646" } ] } ] }, { "uniprot_ac": "P20650", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P20650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20650" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P20650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20650" } ] } ] }, { "uniprot_ac": "P20651", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P20651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20651" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P20651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20651" } ] } ] }, { "uniprot_ac": "P23287", "gene_name": "CNA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23287" } ] } ] }, { "uniprot_ac": "P23467", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23467" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23467" } ] } ] }, { "uniprot_ac": "P23468", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23468" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23468" } ] } ] }, { "uniprot_ac": "P23469", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23469" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23469" } ] } ] }, { "uniprot_ac": "P23470", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23470" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23470" } ] } ] }, { "uniprot_ac": "P23471", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23471", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23471" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23471", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23471" } ] } ] }, { "uniprot_ac": "P23594", "gene_name": "PPH21", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23594" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23594" } ] } ] }, { "uniprot_ac": "P23595", "gene_name": "PPH22", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23595" } ] } ] }, { "uniprot_ac": "P23696", "gene_name": "mts", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23696" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23696" } ] } ] }, { "uniprot_ac": "P23748", "gene_name": "MIH1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P23748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23748" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P23748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23748" } ] } ] }, { "uniprot_ac": "P24666", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P24666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24666" } ] } ] }, { "uniprot_ac": "P25044", "gene_name": "PTP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P25044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25044" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P25044", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25044" } ] } ] }, { "uniprot_ac": "P25646", "gene_name": "PTC6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] }, { "ec_number": "3.1.3.43", "activity": "H2O + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] } ] }, { "uniprot_ac": "P26045", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P26045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26045" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P26045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26045" } ] } ] }, { "uniprot_ac": "P26570", "gene_name": "PPZ1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P26570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26570" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P26570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26570" } ] } ] }, { "uniprot_ac": "P28562", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] } ] }, { "uniprot_ac": "P28563", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] } ] }, { "uniprot_ac": "P28827", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28827" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28827" } ] } ] }, { "uniprot_ac": "P28828", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28828", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28828" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28828", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28828" } ] } ] }, { "uniprot_ac": "P29074", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29074" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29074" } ] } ] }, { "uniprot_ac": "P29349", "gene_name": "csw", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29349" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29349" } ] } ] }, { "uniprot_ac": "P29350", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29350" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29350" } ] } ] }, { "uniprot_ac": "P29351", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29351" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29351" } ] } ] }, { "uniprot_ac": "P29352", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29352" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29352" } ] } ] }, { "uniprot_ac": "P29461", "gene_name": "PTP2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29461" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29461" } ] } ] }, { "uniprot_ac": "P30304", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30304" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30304" } ] } ] }, { "uniprot_ac": "P30305", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30305" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30305" } ] } ] }, { "uniprot_ac": "P30306", "gene_name": "Cdc25b", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30306" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30306" } ] } ] }, { "uniprot_ac": "P30307", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P30307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30307" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P30307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30307" } ] } ] }, { "uniprot_ac": "P32345", "gene_name": "PPH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32345" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32345" } ] } ] }, { "uniprot_ac": "P32598", "gene_name": "GLC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32598" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32598" } ] } ] }, { "uniprot_ac": "P32838", "gene_name": "PPG1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32838" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32838" } ] } ] }, { "uniprot_ac": "P32945", "gene_name": "PPQ1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32945" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32945" } ] } ] }, { "uniprot_ac": "P33329", "gene_name": "PPZ2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P33329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33329" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P33329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33329" } ] } ] }, { "uniprot_ac": "P34137", "gene_name": "ptpA1-2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P34137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34137" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P34137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34137" } ] } ] }, { "uniprot_ac": "P34138", "gene_name": "ptpB", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P34138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34138" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P34138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34138" } ] } ] }, { "uniprot_ac": "P34221", "gene_name": "PTC3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P34221", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34221" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P34221", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34221" } ] } ] }, { "uniprot_ac": "P35182", "gene_name": "PTC1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P35182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35182" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P35182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35182" } ] } ] }, { "uniprot_ac": "P35233", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35233" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35233" } ] } ] }, { "uniprot_ac": "P35234", "gene_name": "Ptpn5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35234" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35234" } ] } ] }, { "uniprot_ac": "P35235", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35235" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35235", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35235" } ] } ] }, { "uniprot_ac": "P35236", "gene_name": "PTPN7", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35236" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35236" } ] } ] }, { "uniprot_ac": "P35813", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P35813", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35813" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P35813", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35813" } ] } ] }, { "uniprot_ac": "P35815", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P35815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35815" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P35815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35815" } ] } ] }, { "uniprot_ac": "P35821", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35821" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35821" } ] } ] }, { "uniprot_ac": "P35822", "gene_name": "Ptprk", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35822" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35822" } ] } ] }, { "uniprot_ac": "P35831", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35831" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35831" } ] } ] }, { "uniprot_ac": "P35832", "gene_name": "Ptp99A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35832" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35832" } ] } ] }, { "uniprot_ac": "P35992", "gene_name": "Ptp10D", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35992" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35992" } ] } ] }, { "uniprot_ac": "P36873", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P36873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36873" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P36873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36873" } ] } ] }, { "uniprot_ac": "P36993", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P36993", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36993" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P36993", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36993" } ] } ] }, { "uniprot_ac": "P38089", "gene_name": "PTC4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38089" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38089" } ] } ] }, { "uniprot_ac": "P38148", "gene_name": "PPS1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] } ] }, { "uniprot_ac": "P38590", "gene_name": "MSG5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P38590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38590" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P38590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38590" } ] } ] }, { "uniprot_ac": "P38757", "gene_name": "NEM1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38757" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38757" } ] } ] }, { "uniprot_ac": "P38797", "gene_name": "PTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38797" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38797" } ] } ] }, { "uniprot_ac": "P39966", "gene_name": "PTC2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P39966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39966" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P39966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39966" } ] } ] }, { "uniprot_ac": "P40048", "gene_name": "PTP3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40048" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40048" } ] } ] }, { "uniprot_ac": "P40081", "gene_name": "", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40081" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40081" } ] } ] }, { "uniprot_ac": "P40084", "gene_name": "RTR1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P40084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40084" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P40084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40084" } ] } ] }, { "uniprot_ac": "P40347", "gene_name": "LTP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P40347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40347" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40347" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40347" } ] } ] }, { "uniprot_ac": "P40421", "gene_name": "rdgC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40421" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40421" } ] } ] }, { "uniprot_ac": "P40479", "gene_name": "SDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P40479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40479" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P40479", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40479" } ] } ] }, { "uniprot_ac": "P41498", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "P41498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41498" } ] } ] }, { "uniprot_ac": "P41499", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P41499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41499" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P41499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41499" } ] } ] }, { "uniprot_ac": "P43378", "gene_name": "PTPN9", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P43378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43378" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P43378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43378" } ] } ] }, { "uniprot_ac": "P48453", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48453" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48453" } ] } ] }, { "uniprot_ac": "P48454", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48454" } ] } ] }, { "uniprot_ac": "P48455", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48455" } ] } ] }, { "uniprot_ac": "P48456", "gene_name": "CanA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48456" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48456" } ] } ] }, { "uniprot_ac": "P48461", "gene_name": "Pp1alpha-96A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48461" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48461" } ] } ] }, { "uniprot_ac": "P48462", "gene_name": "flw", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48462" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48462" } ] } ] }, { "uniprot_ac": "P48964", "gene_name": "Cdc25a", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48964" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48964" } ] } ] }, { "uniprot_ac": "P48965", "gene_name": "Cdc25a", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48965" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48965" } ] } ] }, { "uniprot_ac": "P48966", "gene_name": "Cdc25b", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48966" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48966" } ] } ] }, { "uniprot_ac": "P48967", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P48967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48967" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P48967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48967" } ] } ] }, { "uniprot_ac": "P49443", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P49443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49443" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P49443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49443" } ] } ] }, { "uniprot_ac": "P49445", "gene_name": "Ptpn7", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P49445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49445" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P49445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49445" } ] } ] }, { "uniprot_ac": "P49446", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P49446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49446" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P49446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49446" } ] } ] }, { "uniprot_ac": "P49593", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P49593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49593" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P49593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49593" } ] } ] }, { "uniprot_ac": "P50946", "gene_name": "OCA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P50946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50946" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P50946", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50946" } ] } ] }, { "uniprot_ac": "P51452", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] } ] }, { "uniprot_ac": "P53041", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53041" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53041" } ] } ] }, { "uniprot_ac": "P53042", "gene_name": "Ppp5c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53042" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53042" } ] } ] }, { "uniprot_ac": "P53043", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53043" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53043" } ] } ] }, { "uniprot_ac": "P53538", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53538" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53538" } ] } ] }, { "uniprot_ac": "P54637", "gene_name": "ptpC", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P54637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54637" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P54637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54637" } ] } ] }, { "uniprot_ac": "P54829", "gene_name": "PTPN5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P54829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54829" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P54829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54829" } ] } ] }, { "uniprot_ac": "P54830", "gene_name": "Ptpn5", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P54830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54830" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P54830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54830" } ] } ] }, { "uniprot_ac": "P56180", "gene_name": "TPTE", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P56180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P56180" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P56180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P56180" } ] } ] }, { "uniprot_ac": "P58465", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P58465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58465" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P58465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58465" } ] } ] }, { "uniprot_ac": "P58466", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P58466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58466" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P58466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58466" } ] } ] }, { "uniprot_ac": "P60484", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] } ] }, { "uniprot_ac": "P60487", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine.", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] } ] }, { "uniprot_ac": "P60510", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60510" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60510" } ] } ] }, { "uniprot_ac": "P62136", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62136" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62136" } ] } ] }, { "uniprot_ac": "P62137", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62137" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62137" } ] } ] }, { "uniprot_ac": "P62138", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62138" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62138" } ] } ] }, { "uniprot_ac": "P62140", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] }, { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] } ] }, { "uniprot_ac": "P62141", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] } ] }, { "uniprot_ac": "P62142", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] }, { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] } ] }, { "uniprot_ac": "P62714", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62714", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62714" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62714", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62714" } ] } ] }, { "uniprot_ac": "P62715", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62715" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62715" } ] } ] }, { "uniprot_ac": "P62716", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62716" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62716" } ] } ] }, { "uniprot_ac": "P63087", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63087", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63087" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63087", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63087" } ] } ] }, { "uniprot_ac": "P63088", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63088" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63088" } ] } ] }, { "uniprot_ac": "P63328", "gene_name": "Ppp3ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63328" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63328" } ] } ] }, { "uniprot_ac": "P63329", "gene_name": "Ppp3ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63329" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63329" } ] } ] }, { "uniprot_ac": "P63330", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63330" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63330" } ] } ] }, { "uniprot_ac": "P63331", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63331" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63331" } ] } ] }, { "uniprot_ac": "P67775", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67775" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P67775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67775" } ] } ] }, { "uniprot_ac": "P70289", "gene_name": "Ptprv", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P70289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70289" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P70289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70289" } ] } ] }, { "uniprot_ac": "P80560", "gene_name": "Ptprn2", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P80560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80560" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P80560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80560" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P80560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80560" } ] } ] }, { "uniprot_ac": "P81718", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P81718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P81718" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P81718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P81718" } ] } ] }, { "uniprot_ac": "P82890", "gene_name": "primo-1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82890" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82890" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82890" } ] } ] }, { "uniprot_ac": "P82891", "gene_name": "primo-2", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82891" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82891" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82891" } ] } ] }, { "uniprot_ac": "P97470", "gene_name": "Ppp4c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P97470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97470" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P97470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97470" } ] } ] }, { "uniprot_ac": "P97480", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P97480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97480" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P97480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97480" } ] } ] }, { "uniprot_ac": "P97767", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] } ] }, { "uniprot_ac": "Q00684", "gene_name": "CDC14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q00684", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00684" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q00684", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00684" } ] } ] }, { "uniprot_ac": "Q02256", "gene_name": "YVH1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q02256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q02256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02256" } ] } ] }, { "uniprot_ac": "Q03019", "gene_name": "twe", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q03019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03019" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q03019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03019" } ] } ] }, { "uniprot_ac": "Q03254", "gene_name": "FCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q03254", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03254" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q03254", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03254" } ] } ] }, { "uniprot_ac": "Q03348", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q03348", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03348" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q03348", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03348" } ] } ] }, { "uniprot_ac": "Q05201", "gene_name": "eya", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05201" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05201" } ] } ] }, { "uniprot_ac": "Q05209", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05209" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05209" } ] } ] }, { "uniprot_ac": "Q05547", "gene_name": "Pp1-13C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05547" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05547" } ] } ] }, { "uniprot_ac": "Q05909", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05909" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05909" } ] } ] }, { "uniprot_ac": "Q05922", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05922" } ] } ] }, { "uniprot_ac": "Q05923", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05923" } ] } ] }, { "uniprot_ac": "Q06124", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q06124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06124" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q06124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06124" } ] } ] }, { "uniprot_ac": "Q06180", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q06180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06180" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q06180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06180" } ] } ] }, { "uniprot_ac": "Q08209", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q08209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08209" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q08209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08209" } ] } ] }, { "uniprot_ac": "Q12378", "gene_name": "RTR2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q12378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12378" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q12378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12378" } ] } ] }, { "uniprot_ac": "Q12454", "gene_name": "OCA6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q12454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12454" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q12454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12454" } ] } ] }, { "uniprot_ac": "Q12913", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q12913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12913" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q12913", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12913" } ] } ] }, { "uniprot_ac": "Q12923", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q12923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12923" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q12923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12923" } ] } ] }, { "uniprot_ac": "Q12974", "gene_name": "PTP4A2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q12974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12974" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q12974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12974" } ] } ] }, { "uniprot_ac": "Q13115", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q13115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13115" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13115" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13115" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q13115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13115" } ] } ] }, { "uniprot_ac": "Q13202", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q13202", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13202" } ] } ] }, { "uniprot_ac": "Q13332", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13332" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13332" } ] } ] }, { "uniprot_ac": "Q13615", "gene_name": "MTMR3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.64", "activity": "", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "Q13615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13615" } ] } ] }, { "uniprot_ac": "Q149T7", "gene_name": "Ppm1j", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q149T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q149T7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q149T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q149T7" } ] } ] }, { "uniprot_ac": "Q15256", "gene_name": "PTPRR", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q15256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q15256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15256" } ] } ] }, { "uniprot_ac": "Q15262", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q15262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15262" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q15262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15262" } ] } ] }, { "uniprot_ac": "Q15678", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q15678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15678" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q15678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15678" } ] } ] }, { "uniprot_ac": "Q16659", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] } ] }, { "uniprot_ac": "Q16667", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q16667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16667" } ] } ] }, { "uniprot_ac": "Q16690", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q16690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16690" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q16690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16690" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q16690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16690" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q16690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16690" } ] } ] }, { "uniprot_ac": "Q16825", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q16825", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16825" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q16825", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16825" } ] } ] }, { "uniprot_ac": "Q16827", "gene_name": "PTPRO", "activity": [ { "ec_number": "3.1.3.48", 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O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q1ZXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q1ZXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXG8" } ] } ] }, { "uniprot_ac": "Q27884", "gene_name": "PpV", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q27884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q27884" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q27884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q27884" } ] } ] }, { "uniprot_ac": "Q27889", "gene_name": "Pp2B-14D", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q27889", 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"https://www.uniprot.org/uniprot/Q5BJ92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5BJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5BJ92" } ] } ] }, { "uniprot_ac": "Q5FVI9", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5FVI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FVI9" } ] } ] }, { "uniprot_ac": "Q5FWT7", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5FWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FWT7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5FWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5FWT7" } ] } ] }, { "uniprot_ac": "Q5I0E6", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5I0E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5I0E6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5I0E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5I0E6" } ] } ] }, { "uniprot_ac": "Q5JR12", "gene_name": "PPM1J", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5JR12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5JR12" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5JR12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5JR12" } ] } ] }, { "uniprot_ac": "Q5LJN2", "gene_name": "Pp1-Y2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5LJN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5LJN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5LJN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5LJN2" } ] } ] }, { "uniprot_ac": "Q5M821", "gene_name": "Ppm1h", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5M821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5M821" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5M821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5M821" } ] } ] }, { "uniprot_ac": "Q5PQT2", "gene_name": "Mtmr3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.64", "activity": "", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "Q5PQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT2" } ] } ] }, { "uniprot_ac": "Q5SGD2", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5SGD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SGD2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5SGD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SGD2" } ] } ] }, { "uniprot_ac": "Q5SW75", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5SW75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SW75" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5SW75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SW75" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5SW75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SW75" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5SW75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SW75" } ] } ] }, { "uniprot_ac": "Q5XIS1", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5XIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5XIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5XIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5XIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS1" } ] } ] }, { "uniprot_ac": "Q60676", "gene_name": "Ppp5c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q60676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60676" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q60676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60676" } ] } ] }, { "uniprot_ac": "Q61074", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q61074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61074" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q61074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61074" } ] } ] }, { "uniprot_ac": "Q61152", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q61152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q61152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61152" } ] } ] }, { "uniprot_ac": "Q62130", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62130" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62130" } ] } ] }, { "uniprot_ac": "Q62132", "gene_name": "Ptprr", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62132" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62132" } ] } ] }, { "uniprot_ac": "Q62136", "gene_name": "Ptpn21", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62136" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62136" } ] } ] }, { "uniprot_ac": "Q62656", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62656" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62656" } ] } ] }, { "uniprot_ac": "Q62728", "gene_name": "Ptpn21", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62728" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62728" } ] } ] }, { "uniprot_ac": "Q62767", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] } ] }, { "uniprot_ac": "Q62797", "gene_name": "Ptpro", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62797" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62797" } ] } ] }, { "uniprot_ac": "Q63340", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q63340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63340" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q63340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63340" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q63340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63340" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q63340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63340" } ] } ] }, { "uniprot_ac": "Q63475", "gene_name": "Ptprn2", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q63475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63475" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q63475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63475" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q63475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63475" } ] } ] }, { "uniprot_ac": "Q63739", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q63739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63739" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q63739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63739" } ] } ] }, { "uniprot_ac": "Q63HR2", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q63HR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63HR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q63HR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63HR2" } ] } ] }, { "uniprot_ac": "Q641Y6", "gene_name": "Ppm1j", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q641Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Y6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q641Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Y6" } ] } ] }, { "uniprot_ac": "Q641Z2", "gene_name": "Ptpn9", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q641Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q641Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z2" } ] } ] }, { "uniprot_ac": "Q64346", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] } ] }, { "uniprot_ac": "Q64455", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64455", "database": 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"https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] } ] }, { "uniprot_ac": "Q7KVM5", "gene_name": "PpN58A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KVM5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7KVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KVM5" } ] } ] }, { "uniprot_ac": "Q7TNL7", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] } ] }, { "uniprot_ac": "Q7TSG2", "gene_name": "Ctdp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSG2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7TSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSG2" } ] } ] }, { "uniprot_ac": "Q7YSW8", "gene_name": "canA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7YSW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7YSW8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7YSW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7YSW8" } ] } ] }, { "uniprot_ac": "Q80TL0", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q80TL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TL0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q80TL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TL0" } ] } ] }, { "uniprot_ac": "Q80TZ3", "gene_name": "Dnajc6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + 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"https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] } ] }, { "uniprot_ac": "Q86BN8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] } ] }, { "uniprot_ac": "Q86IL4", "gene_name": "", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86IL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IL4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q86IL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IL4" } ] } ] }, { "uniprot_ac": "Q86V88", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q86V88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V88" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86V88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q86V88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V88" } ] } ] }, { "uniprot_ac": "Q8BFS6", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFS6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BFS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFS6" } ] } ] }, { "uniprot_ac": "Q8BFV3", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] } ] }, { "uniprot_ac": "Q8BGG7", "gene_name": "Ubash3b", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGG7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BGG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGG7" } ] } ] }, { "uniprot_ac": "Q8BGL1", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BGL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BGL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGL1" } ] } ] }, { "uniprot_ac": "Q8BGR9", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGR9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGR9" } ] } ] }, { "uniprot_ac": "Q8BHN0", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BHN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BHN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHN0" } ] } ] }, { "uniprot_ac": "Q8BK84", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": 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"id": "Q8BUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BUM3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BUM3" } ] } ] }, { "uniprot_ac": "Q8BX07", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX07" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX07" } ] } ] }, { "uniprot_ac": "Q8BX10", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BX10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX10" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BX10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX10" } ] } ] }, { "uniprot_ac": "Q8BXA7", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXA7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXA7" } ] } ] }, { "uniprot_ac": "Q8BXN7", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXN7" } ] }, { "ec_number": "3.1.3.52", "activity": "H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "Q8BXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXN7" } ] } ] }, { "uniprot_ac": "Q8CE08", "gene_name": "Acp3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "Q8CE08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE08" } ] } ] }, { "uniprot_ac": "Q8CGA0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8CGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGA0" } ] } ] }, { "uniprot_ac": "Q8CGB6", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CGB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGB6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8CGB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGB6" } ] } ] }, { "uniprot_ac": "Q8CHE4", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHE4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8CHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHE4" } ] } ] }, { "uniprot_ac": "Q8CHP8", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "Q8CHP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHP8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CHP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHP8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "Q8CHP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHP8" } ] } ] }, { "uniprot_ac": "Q8IXW5", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8IXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IXW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8IXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IXW5" } ] } ] }, { "uniprot_ac": "Q8K296", "gene_name": "Mtmr3", "activity": [ { "ec_number": "3.1.3.64", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate.", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.64", "activity": "", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] }, { "ec_number": "3.1.3.95", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate.", "evidence": [ { "id": "Q8K296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K296" } ] } ] }, { "uniprot_ac": "Q8K330", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] } ] }, { "uniprot_ac": "Q8K4T5", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] } ] }, { "uniprot_ac": "Q8N3J5", "gene_name": "PPM1K", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8N3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N3J5" } ] }, { "ec_number": "3.1.3.52", "activity": "H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "Q8N3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N3J5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8N3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N3J5" } ] } ] }, { "uniprot_ac": "Q8N819", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8N819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N819" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8N819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N819" } ] } ] }, { "uniprot_ac": "Q8NEJ0", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] } ] }, { "uniprot_ac": "Q8NI37", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NI37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NI37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8NI37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NI37" } ] } ] }, { "uniprot_ac": "Q8R0F6", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R0F6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8R0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R0F6" } ] } ] }, { "uniprot_ac": "Q8R4V2", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] } ] }, { "uniprot_ac": "Q8ST13", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8ST13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8ST13" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8ST13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8ST13" } ] } ] }, { "uniprot_ac": "Q8T9S7", "gene_name": "pteN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] } ] }, { "uniprot_ac": "Q8TE77", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] } ] }, { "uniprot_ac": "Q8TF42", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8TF42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF42" } ] } ] }, { "uniprot_ac": "Q8VC34", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VC34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VC34" } ] } ] }, { "uniprot_ac": "Q8VD52", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine.", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] } ] }, { "uniprot_ac": "Q8VE01", "gene_name": "Dusp18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] } ] }, { "uniprot_ac": "Q8WTR2", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] } ] }, { "uniprot_ac": "Q8WUK0", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] } ] }, { "uniprot_ac": "Q8WVY7", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WVY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WVY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WVY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WVY7" } ] } ] }, { "uniprot_ac": "Q8WY54", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WY54" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WY54" } ] } ] }, { "uniprot_ac": "Q8WYL5", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] } ] }, { "uniprot_ac": "Q91WF7", "gene_name": "Fig4", "activity": [ { 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L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] } ] }, { "uniprot_ac": "Q91XS1", "gene_name": "Mtmr4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q91XS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q91XS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS1" } ] } ] }, { "uniprot_ac": "Q91Z46", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": 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"alph", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q961C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q961C5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q961C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q961C5" } ] } ] }, { "uniprot_ac": "Q96GD0", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine.", "evidence": [ { "id": "Q96GD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD0" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q96GD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD0" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "Q96GD0", "database": 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"activity": "", "evidence": [ { "id": "Q96MI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96MI6" } ] } ] }, { "uniprot_ac": "Q99502", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] } ] }, { "uniprot_ac": "Q99504", "gene_name": 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L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] } ] }, { "uniprot_ac": "Q99M80", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q99M80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99M80" } ] }, { "ec_number": "3.1.3.48", 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"https://www.uniprot.org/uniprot/Q9D9D8" } ] } ] }, { "uniprot_ac": "Q9DBB1", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] } ] }, { "uniprot_ac": "Q9ESS0", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + 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