{ "uniprot_canonical_ac": "O60231-1", "uniprot_ac": "O60231", "uniprot_id": "DHX16_HUMAN", "mass": { "chemical_mass": 119264.0, "monoisotopic_mass": 119264.0 }, "refseq": { "ac": "NP_001157711", "name": "pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform 2", "summary": "DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2018].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" }, "gene_names": [ { "name": "DHX16", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O60231", "id": "O60231" }, { "name": "DBP2; DDX16; NMOAS; PRO2014; Prp2; PRP8; PRPF2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711", "id": "NP_001157711" }, { "name": "DBP2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O60231", "id": "O60231" }, { "name": "DDX16", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O60231", "id": "O60231" }, { "name": "DHX16", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711", "id": "NP_001157711" }, { "name": "KIAA0577", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O60231", "id": "O60231" }, { "name": "PRP2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O60231", "id": "O60231" }, { "name": "hCG_26008", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O60231", "id": "O60231" } ], "protein_names": [ { "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O60231" }, { "name": "3.6.4.13", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O60231" }, { "name": "ATP-dependent RNA helicase #3; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; DEAH-box protein 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; pre-mRNA processing factor 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711", "id": "NP_001157711" }, { "name": "ATP-dependent RNA helicase #3", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O60231" }, { "name": "DEAH-box protein 16", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O60231" }, { "name": "pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711", "id": "NP_001157711" } ], "function": [ { "annotation": "DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2018].", "evidence": [ { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" } ] }, { "annotation": "Infantile onset encephalomyopathy, retinopathy, optic atrophy, and mitochondrial DNA depletion associated with a novel pathogenic DHX16 variant.", "evidence": [ { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" }, { "database": "PubMed", "id": "37574199", "url": "https://glygen.org/publication/PubMed/37574199" } ] }, { "annotation": "Missense mutation in DHX16 gene is associated with neurodevelopmental disorder.", "evidence": [ { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" }, { "database": "PubMed", "id": "31256877", "url": "https://glygen.org/publication/PubMed/31256877" } ] }, { "annotation": "Required for pre-mRNA splicing as component of the spliceosome (PubMed:20423332, PubMed:20841358, PubMed:25296192, PubMed:29360106). Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Plays also a role in innate antiviral response by acting as a pattern recognition receptor sensing splicing signals in viral RNA (PubMed:35263596). Mechanistically, TRIM6 promotes the interaction between unanchored 'Lys-48'-polyubiquitin chains and DHX16, leading to DHX16 interaction with RIGI and ssRNA to amplify RIGI-dependent innate antiviral immune responses (PubMed:35263596).", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231#function" }, { "database": "PubMed", "id": "35263596", "url": "https://glygen.org/publication/PubMed/35263596" }, { "database": "PubMed", "id": "25296192", "url": "https://glygen.org/publication/PubMed/25296192" }, { "database": "PubMed", "id": "20841358", "url": "https://glygen.org/publication/PubMed/20841358" }, { "database": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" }, { "database": "PubMed", "id": "29360106", "url": "https://glygen.org/publication/PubMed/29360106" }, { "database": "PubMed", "id": "33509932", "url": "https://glygen.org/publication/PubMed/33509932" } ] }, { "annotation": "The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.", "evidence": [ { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" }, { "database": "PubMed", "id": "35263596", "url": "https://glygen.org/publication/PubMed/35263596" } ] } ], "disease": [ { "disease_id": "MONDO:0032890", "recommended_name": { "id": "MONDO:0032890", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032890", "name": "neuromuscular disease and ocular or auditory anomalies with or without seizures", "description": "" }, "synonyms": [ { "id": "MONDO:0032890", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032890", "name": "NEUROMUSCULAR DISEASE AND OCULAR OR AUDITORY ANOMALIES WITH OR WITHOUT SEIZURES", "description": "" }, { "id": "MONDO:0032890", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032890", "name": "NMOAS", "description": "" }, { "id": "MIM:618733", "resource": "MIM", "url": "https://www.omim.org/entry/618733", "name": "Neuromuscular oculoauditory syndrome", "description": "Neuromuscular oculoauditory syndrome" } ], "evidence": [ { "id": "618733", "database": "MIM", "url": "https://www.omim.org/entry/618733" } ] } ], "snv": [], "mutagenesis": [ { "start_pos": 428, "end_pos": 428, "sequence_org": "K", "sequence_mut": "A", "comment": "Impairs pre-mRNA splicing activity.", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" } ] }, { "start_pos": 520, "end_pos": 520, "sequence_org": "D", "sequence_mut": "A", "comment": "Impairs pre-mRNA splicing activity.", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" } ] }, { "start_pos": 523, "end_pos": 523, "sequence_org": "H", "sequence_mut": "A", "comment": "No loss of pre-mRNA splicing activity.", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" } ] }, { "start_pos": 552, "end_pos": 552, "sequence_org": "S", "sequence_mut": "L", "comment": "Dominant-negative mutant. Impairs pre-mRNA splicing activity. Fails to interact with any of viral RNA forms.", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "PubMed", "id": "35263596", "url": "https://glygen.org/publication/PubMed/35263596" }, { "database": "PubMed", "id": "25296192", "url": "https://glygen.org/publication/PubMed/25296192" }, { "database": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" } ] }, { "start_pos": 724, "end_pos": 724, "sequence_org": "G", "sequence_mut": "N", "comment": "Dominant-negative mutant. Impairs pre-mRNA splicing activity. Fails to interact with any of viral RNA forms.", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "PubMed", "id": "35263596", "url": "https://glygen.org/publication/PubMed/35263596" }, { "database": "PubMed", "id": "25296192", "url": "https://glygen.org/publication/PubMed/25296192" }, { "database": "PubMed", "id": "20841358", "url": "https://glygen.org/publication/PubMed/20841358" }, { "database": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" } ] } ], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "87.83", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "84.76", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "81.64", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "68.39", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "91.45", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "92.21", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "77.2", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "88.28", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "92.55", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "76.74", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "85.79", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "92.85", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "91.07", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000204560", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000204560" } ] } ], "expression_disease": [ { "significant": "No", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, intestinal", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Urinary bladder cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": 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"https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Head and neck cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Lung cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1324", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "Nonsmall cell lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "alveolar cell carcinoma", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung neoplasm", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Breast cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1612", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "A thoracic cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid neoplasm", "description": "" } ] } ] }, { "significant": "No", "trend": "up", "name": "Kidney cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:263", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant hepato-biliary neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant tumor of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "non-resectable primary hepatic malignant neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "primary liver cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "primary malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "resectable malignant neoplasm of the liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, not specified as primary or secondary", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Uterine cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:363", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:363", "recommended_name": { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine cancer", "description": "A female reproductive organ cancer that is located_in the uterus." }, "synonyms": [ { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "CA - cancer of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "Tumour of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterus neoplasm", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Esophageal cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:5041", "evidence": [ { "database": "BioXpress", "id": "O60231", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O60231" } ], "disease": [ { "disease_id": "DOID:5041", "recommended_name": { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "hsa:8449", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:8449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "603405", "url": "http://www.omim.org/entry/603405", "database": "MIM", "categories": [ "Other" ] }, { "id": "618733", "url": "http://www.omim.org/entry/618733", "database": "MIM", "categories": [ "Other" ] }, { "id": "NX_O60231", "url": "https://www.nextprot.org/entry/NX_O60231", "database": "neXtProt", "categories": [ "Protein", "Organism-specific" ] }, { "id": "O60231", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60231", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "HITLMNV", "url": "https://omabrowser.org/oma/group/HITLMNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5488182at2759", "url": "http://www.orthodb.org/?query=5488182at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "5Z56", "url": "https://www.rcsb.org/structure/5Z56", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5Z57", "url": "https://www.rcsb.org/structure/5Z57", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5Z58", "url": "https://www.rcsb.org/structure/5Z58", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6FF7", "url": "https://www.rcsb.org/structure/6FF7", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7DVQ", "url": "https://www.rcsb.org/structure/7DVQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7QTT", "url": "https://www.rcsb.org/structure/7QTT", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8CH6", "url": "https://www.rcsb.org/structure/8CH6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00270", "url": "http://pfam.xfam.org/family/PF00270", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00271", "url": "http://pfam.xfam.org/family/PF00271", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF04408", "url": "http://pfam.xfam.org/family/PF04408", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07717", "url": "http://pfam.xfam.org/family/PF07717", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF21010", "url": "http://pfam.xfam.org/family/PF21010", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "O60231", "url": "https://pharos.nih.gov/targets/O60231", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR_O60231", "url": "http://purl.obolibrary.org/obo/PR_O60231", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T8Y5", "url": "https://www.uniprot.org/uniprot/A0A140T8Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8Y5-1", "url": "https://www.uniprot.org/uniprot/A0A140T8Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T947", "url": "https://www.uniprot.org/uniprot/A0A140T947", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T947-1", "url": "https://www.uniprot.org/uniprot/A0A140T947-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T9T4", "url": "https://www.uniprot.org/uniprot/A0A140T9T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T9T4-1", "url": "https://www.uniprot.org/uniprot/A0A140T9T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AB15", "url": "https://www.uniprot.org/uniprot/A2AB15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AB15-1", "url": "https://www.uniprot.org/uniprot/A2AB15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O60231-1", "url": "https://www.uniprot.org/uniprot/O60231-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5SQH5", "url": "https://www.uniprot.org/uniprot/Q5SQH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5SQH5-1", "url": "https://www.uniprot.org/uniprot/Q5SQH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG", "length": 1041, "header": "sp|O60231-1|DHX16_HUMAN Isoform 1 of Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 CANONICAL=O60231-1" }, "isoforms": [ { "isoform_ac": "A0A140T8Y5-1", "url": "", "sequence": { "sequence": "MESQPAQECLMQMFLPIEPACFVEWLGTSPSQLGVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDGAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG", "length": 560, "header": "tr|A0A140T8Y5-1|A0A140T8Y5_HUMAN Computationally mapped isoform of RNA helicase OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=1 CANONICAL=O60231-1" }, "locus": { "chromosome": "HSCHR6_MHC_QBL_CTG1", "start_pos": 1916969, "end_pos": 1908327, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000383576.7", "url": "https://www.ensembl.org/id/ENST00000383576.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000373070.3", "url": "https://www.ensembl.org/id/ENSP00000373070.3" } ] } }, { "isoform_ac": "A0A140T947-1", "url": "", "sequence": { "sequence": "MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARK", "length": 669, "header": "tr|A0A140T947-1|A0A140T947_HUMAN Computationally mapped isoform of RNA helicase OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=1 CANONICAL=O60231-1" }, "locus": { "chromosome": "HSCHR6_MHC_APD_CTG1", "start_pos": 2002347, "end_pos": 1988978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000450902.6", "url": "https://www.ensembl.org/id/ENST00000450902.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000391789.2", "url": "https://www.ensembl.org/id/ENSP00000391789.2" } ] } }, { "isoform_ac": "A0A140T9T4-1", "url": "", "sequence": { "sequence": "MESQPAQECLMQMFLPIEPACFVEWLGTSPSQLGVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARK", "length": 188, "header": "tr|A0A140T9T4-1|A0A140T9T4_HUMAN Computationally mapped isoform of RNA helicase OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=1 CANONICAL=O60231-1" }, "locus": { "chromosome": "HSCHR6_MHC_APD_CTG1", "start_pos": 1991362, "end_pos": 1988978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000456005.5", "url": "https://www.ensembl.org/id/ENST00000456005.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000412716.1", "url": "https://www.ensembl.org/id/ENSP00000412716.1" } ] } }, { "isoform_ac": "A2AB15-1", "url": "", "sequence": { "sequence": "MSEDPRGPKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQL", "length": 295, "header": "tr|A2AB15-1|A2AB15_HUMAN Computationally mapped isoform of Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=1 CANONICAL=O60231-1" }, "locus": { "chromosome": "HSCHR6_MHC_QBL_CTG1", "start_pos": 1928095, "end_pos": 1920244, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000448766.1", "url": "https://www.ensembl.org/id/ENST00000448766.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000403116.1", "url": "https://www.ensembl.org/id/ENSP00000403116.1" } ] } }, { "isoform_ac": "O60231-1", "url": "", "sequence": { "sequence": "MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG", "length": 1041, "header": "sp|O60231-1|DHX16_HUMAN Isoform 1 of Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 CANONICAL=O60231-1" }, "locus": { "chromosome": "6", "start_pos": 30672841, "end_pos": 30653245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000376442.8", "url": "https://www.ensembl.org/id/ENST00000376442.8" }, { "database": "Ensembl Peptide", "id": "ENSP00000365625.3", "url": "https://www.ensembl.org/id/ENSP00000365625.3" } ] } }, { "isoform_ac": "Q5SQH5-1", "url": "", "sequence": { "sequence": "MESQPAQECLMQMFLPIEPACFVEWLGTSPSQLGVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG", "length": 560, "header": "tr|Q5SQH5-1|Q5SQH5_HUMAN Computationally mapped isoform of RNA helicase OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=1 CANONICAL=O60231-1" }, "locus": { "chromosome": "HSCHR6_MHC_MANN_CTG1", "start_pos": 1972109, "end_pos": 1963469, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000414052.6", "url": "https://www.ensembl.org/id/ENST00000414052.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000406462.2", "url": "https://www.ensembl.org/id/ENSP00000406462.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "O60231", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60231" }, { "id": "23301498", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23301498" }, { "id": "34725712", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34725712" }, { "id": "34019948", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34019948" }, { "id": "28510447", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28510447" } ] } ], "phosphorylation": [ { "start_pos": 103, "end_pos": 103, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "PubMed", "id": "17081983", "url": "https://glygen.org/publication/PubMed/17081983" }, { "database": "PubMed", "id": "18669648", "url": "https://glygen.org/publication/PubMed/18669648" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" }, { "database": "PubMed", "id": "16964243", "url": "https://glygen.org/publication/PubMed/16964243" }, { "database": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" }, { "database": "PubMed", "id": "21406692", "url": "https://glygen.org/publication/PubMed/21406692" }, { "database": "PubMed", "id": "18318008", "url": "https://glygen.org/publication/PubMed/18318008" }, { "database": "PubMed", "id": "19690332", "url": "https://glygen.org/publication/PubMed/19690332" }, { "database": "iPTMnet", "id": "O60231", "url": 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"database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "19103666", "url": "https://glygen.org/publication/PubMed/19103666" } ] }, { "title": "TFIP11 interacts with mDEAH9, an RNA helicase involved in spliceosome disassembly.", "journal": "International journal of molecular sciences", "date": "2008", "authors": "Wen X, Tannukit S, Paine ML", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "19165350", "url": "https://glygen.org/publication/PubMed/19165350" } ] }, { "title": "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.", "journal": "Analytical chemistry", "date": "2009", "authors": "Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S", "evidence": [ { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "19413330", "url": "https://glygen.org/publication/PubMed/19413330" } ] }, { "title": "Phosphoproteomic analysis of distinct tumor cell lines in response to nocodazole treatment.", "journal": "Proteomics", "date": "2009", "authors": "Nagano K, Shinkawa T, Mutoh H, Kondoh O, Morimoto S, Inomata N, Ashihara M, Ishii N, Aoki Y, Haramura M", "evidence": [ { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "19415658", "url": "https://glygen.org/publication/PubMed/19415658" } ] }, { "title": "Exon, intron and splice site locations in the spliceosomal B complex.", "journal": "The EMBO journal", "date": "2009", "authors": "Wolf E, Kastner B, Deckert J, Merz C, Stark H, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "19536130", "url": "https://glygen.org/publication/PubMed/19536130" } ] }, { "title": "Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Pan C, Olsen JV, Daub H, Mann M", "evidence": [ { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "19651622", "url": "https://glygen.org/publication/PubMed/19651622" } ] }, { "title": "Phosphoproteomic analysis of human embryonic stem cells.", "journal": "Cell stem cell", "date": "2009", "authors": "Brill LM, Xiong W, Lee KB, Ficarro SB, Crain A, Xu Y, Terskikh A, Snyder EY, Ding S", "evidence": [ { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "19664994", "url": "https://glygen.org/publication/PubMed/19664994" } ] }, { "title": "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.", "journal": "Science signaling", "date": "2009", "authors": "Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "19690332", "url": "https://glygen.org/publication/PubMed/19690332" } ] }, { "title": "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.", "journal": "Science signaling", "date": "2010", "authors": "Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ] }, { "title": "Phosphoproteome analysis of human liver tissue by long-gradient nanoflow LC coupled with multiple stage MS analysis.", "journal": "Electrophoresis", "date": "2010", "authors": "Han G, Ye M, Liu H, Song C, Sun D, Wu Y, Jiang X, Chen R, Wang C, Wang L, Zou H", "evidence": [ { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "20166139", "url": "https://glygen.org/publication/PubMed/20166139" } ] }, { "title": "Contribution of DEAH-box protein DHX16 in human pre-mRNA splicing.", "journal": "The Biochemical journal", "date": "2010", "authors": "Gencheva M, Kato M, Newo AN, Lin RJ", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "20423332", "url": "https://glygen.org/publication/PubMed/20423332" } ] }, { "title": "Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Gencheva M, Lin TY, Wu X, Yang L, Richard C, Jones M, Lin SB, Lin RJ", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "reference": [ { "type": "PubMed", "id": "20841358", "url": "https://glygen.org/publication/PubMed/20841358" } ] }, { "title": "Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis.", "journal": "RNA (New York, N.Y.)", "date": "2010", "authors": "Bessonov S, Anokhina M, Krasauskas A, Golas MM, Sander B, Will CL, Urlaub H, Stark H, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "20980672", "url": "https://glygen.org/publication/PubMed/20980672" } ] }, { "title": "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.", "journal": "Science signaling", "date": "2011", "authors": "Rigbolt KT, Prokhorova TA, Akimov V, Henningsen J, Johansen PT, Kratchmarova I, Kassem M, Mann M, Olsen JV, Blagoev B", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "21406692", "url": "https://glygen.org/publication/PubMed/21406692" } ] }, { "title": "Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method.", "journal": "Molecular and cellular biology", "date": "2011", "authors": "Agafonov DE, Deckert J, Wolf E, Odenwalder P, Bessonov S, Will CL, Urlaub H, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "21536652", "url": "https://glygen.org/publication/PubMed/21536652" } ] }, { "title": "Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles.", "journal": "Genes & development", "date": "1990", "authors": "Hausner TP, Giglio LM, Weiner AM", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "2176635", "url": "https://glygen.org/publication/PubMed/2176635" } ] }, { "title": "Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs.", "journal": "Nucleic acids research", "date": "2012", "authors": "Makarov EM, Owen N, Bottrill A, Makarova OV", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "22110043", "url": "https://glygen.org/publication/PubMed/22110043" } ] }, { "title": "Dynamic protein-protein interaction wiring of the human spliceosome.", "journal": "Molecular cell", "date": "2012", "authors": "Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, Luhrmann R, Stelzl U", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "22365833", "url": "https://glygen.org/publication/PubMed/22365833" } ] }, { "title": "CWC22 connects pre-mRNA splicing and exon junction complex assembly.", "journal": "Cell reports", "date": "2012", "authors": "Steckelberg AL, Boehm V, Gromadzka AM, Gehring NH", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "22959432", "url": "https://glygen.org/publication/PubMed/22959432" } ] }, { "title": "Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly.", "journal": "Nature structural & molecular biology", "date": "2012", "authors": "Barbosa I, Haque N, Fiorini F, Barrandon C, Tomasetto C, Blanchette M, Le Hir H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "22961380", "url": "https://glygen.org/publication/PubMed/22961380" } ] }, { "title": "Toward a comprehensive characterization of a human cancer cell phosphoproteome.", "journal": "Journal of proteome research", "date": "2013", "authors": "Zhou H, Di Palma S, Preisinger C, Peng M, Polat AN, Heck AJ, Mohammed S", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "iPTMnet", "id": "O60231", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60231" } ], "reference": [ { "type": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" } ] }, { "title": "Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA.", "journal": "Nucleic acids research", "date": "2013", "authors": "Chi B, Wang Q, Wu G, Tan M, Wang L, Shi M, Chang X, Cheng H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "23222130", "url": "https://glygen.org/publication/PubMed/23222130" } ] }, { "title": "Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alexandrov A, Colognori D, Shu MD, Steitz JA", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "23236153", "url": "https://glygen.org/publication/PubMed/23236153" } ] }, { "title": "Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry.", "journal": "Journal of proteome research", "date": "2013", "authors": "Hahne H, Sobotzki N, Nyberg T, Helm D, Borodkin VS, van Aalten DM, Agnew B, Kuster B", "evidence": [ { "database": "O-GlcNAc Database", "id": "O60231", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60231" } ], "reference": [ { "type": "PubMed", "id": "23301498", "url": "https://glygen.org/publication/PubMed/23301498" } ] }, { "title": "Rearrangements within human spliceosomes captured after exon ligation.", "journal": "RNA (New York, N.Y.)", "date": "2013", "authors": "Ilagan JO, Chalkley RJ, Burlingame AL, Jurica MS", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "23345524", "url": "https://glygen.org/publication/PubMed/23345524" } ] }, { "title": "RNA catalyses nuclear pre-mRNA splicing.", "journal": "Nature", "date": "2013", "authors": "Fica SM, Tuttle N, Novak T, Li NS, Lu J, Koodathingal P, Dai Q, Staley JP, Piccirilli JA", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "24196718", "url": "https://glygen.org/publication/PubMed/24196718" } ] }, { "title": "Identification of a novel component C2ORF3 in the lariat-intron complex: lack of C2ORF3 interferes with pre-mRNA splicing via intron turnover pathway.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "2014", "authors": "Yoshimoto R, Okawa K, Yoshida M, Ohno M, Kataoka N", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "24304693", "url": "https://glygen.org/publication/PubMed/24304693" } ] }, { "title": "Mass spectrometry-based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count.", "journal": "RNA (New York, N.Y.)", "date": "2014", "authors": "Schmidt C, Gronborg M, Deckert J, Bessonov S, Conrad T, Luhrmann R, Urlaub H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "24448447", "url": "https://glygen.org/publication/PubMed/24448447" } ] }, { "title": "A missense mutation in the splicing factor gene DHX38 is associated with early-onset retinitis pigmentosa with macular coloboma.", "journal": "Journal of medical genetics", "date": "2014", "authors": "Ajmal M, Khan MI, Neveling K, Khan YM, Azam M, Waheed NK, Hamel CP, Ben-Yosef T, De Baere E, Koenekoop RK, Collin RW, Qamar R, Cremers FP", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "24737827", "url": "https://glygen.org/publication/PubMed/24737827" } ] }, { "title": "Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28.", "journal": "Acta crystallographica. Section D, Biological crystallography", "date": "2014", "authors": "Mohlmann S, Mathew R, Neumann P, Schmitt A, Luhrmann R, Ficner R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "24914973", "url": "https://glygen.org/publication/PubMed/24914973" } ] }, { "title": "GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo.", "journal": "Bioscience reports", "date": "2014", "authors": "Zang S, Lin TY, Chen X, Gencheva M, Newo AN, Yang L, Rossi D, Hu J, Lin SB, Huang A, Lin RJ", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "reference": [ { "type": "PubMed", "id": "25296192", "url": "https://glygen.org/publication/PubMed/25296192" } ] }, { "title": "Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.", "journal": "eLife", "date": "2015", "authors": "Kondo Y, Oubridge C, van Roon AM, Nagai K", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "25555158", "url": "https://glygen.org/publication/PubMed/25555158" } ] }, { "title": "Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.", "journal": "Genes & development", "date": "1989", "authors": "Wu J, Manley JL", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "2558966", "url": "https://glygen.org/publication/PubMed/2558966" } ] }, { "title": "Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site.", "journal": "RNA (New York, N.Y.)", "date": "2015", "authors": "Boesler C, Rigo N, Agafonov DE, Kastner B, Urlaub H, Will CL, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "26385511", "url": "https://glygen.org/publication/PubMed/26385511" } ] }, { "title": "Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.", "journal": "Nucleic acids research", "date": "2015", "authors": "Crisci A, Raleff F, Bagdiul I, Raabe M, Urlaub H, Rain JC, Kramer A", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "26420826", "url": "https://glygen.org/publication/PubMed/26420826" } ] }, { "title": "Noncanonical registers and base pairs in human 5' splice-site selection.", "journal": "Nucleic acids research", "date": "2016", "authors": "Tan J, Ho JX, Zhong Z, Luo S, Chen G, Roca X", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "26969736", "url": "https://glygen.org/publication/PubMed/26969736" } ] }, { "title": "A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity.", "journal": "Nature communications", "date": "2016", "authors": "Boesler C, Rigo N, Anokhina MM, Tauchert MJ, Agafonov DE, Kastner B, Urlaub H, Ficner R, Will CL, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "27377154", "url": "https://glygen.org/publication/PubMed/27377154" } ] }, { "title": "Cryo-EM structure of the spliceosome immediately after branching.", "journal": "Nature", "date": "2016", "authors": "Galej WP, Wilkinson ME, Fica SM, Oubridge C, Newman AJ, Nagai K", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "27459055", "url": "https://glygen.org/publication/PubMed/27459055" } ] }, { "title": "Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways.", "journal": "Nucleic acids research", "date": "2017", "authors": "Chen L, Weinmeister R, Kralovicova J, Eperon LP, Vorechovsky I, Hudson AJ, Eperon IC", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "27683217", "url": "https://glygen.org/publication/PubMed/27683217" } ] }, { "title": "Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.", "journal": "Journal of cell science", "date": "2017", "authors": "Zanini IM, Soneson C, Lorenzi LE, Azzalin CM", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "28062851", "url": "https://glygen.org/publication/PubMed/28062851" } ] }, { "title": "Cryo-EM structure of a human spliceosome activated for step 2 of splicing.", "journal": "Nature", "date": "2017", "authors": "Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "28076346", "url": "https://glygen.org/publication/PubMed/28076346" } ] }, { "title": "An Atomic Structure of the Human Spliceosome.", "journal": "Cell", "date": "2017", "authors": "Zhang X, Yan C, Hang J, Finci LI, Lei J, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "28502770", "url": "https://glygen.org/publication/PubMed/28502770" } ] }, { "title": "Synthesis of a Highly Azide-Reactive and Thermosensitive Biofunctional Reagent for Efficient Enrichment and Large-Scale Identification of O-GlcNAc Proteins by Mass Spectrometry.", "journal": "Analytical chemistry", "date": "2017", "authors": "Zhang W, Liu T, Dong H, Bai H, Tian F, Shi Z, Chen M, Wang J, Qin W, Qian X", "evidence": [ { "database": "O-GlcNAc Database", "id": "O60231", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60231" } ], "reference": [ { "type": "PubMed", "id": "28510447", "url": "https://glygen.org/publication/PubMed/28510447" } ] }, { "title": "Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.", "journal": "Cell", "date": "2017", "authors": "Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will CL, Urlaub H, Kastner B, Luhrmann R, Stark H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "28781166", "url": "https://glygen.org/publication/PubMed/28781166" } ] }, { "title": "Structure of a human catalytic step I spliceosome.", "journal": "Science (New York, N.Y.)", "date": "2018", "authors": "Zhan X, Yan C, Zhang X, Lei J, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "29301961", "url": "https://glygen.org/publication/PubMed/29301961" } ] }, { "title": "Structure of the human activated spliceosome in three conformational states.", "journal": "Cell research", "date": "2018", "authors": "Zhang X, Yan C, Zhan X, Li L, Lei J, Shi Y", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "29360106", "url": "https://glygen.org/publication/PubMed/29360106" } ] }, { "title": "Structure and Conformational Dynamics of the Human Spliceosomal B(act) Complex.", "journal": "Cell", "date": "2018", "authors": "Haselbach D, Komarov I, Agafonov DE, Hartmuth K, Graf B, Dybkov O, Urlaub H, Kastner B, Luhrmann R, Stark H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "29361316", "url": "https://glygen.org/publication/PubMed/29361316" } ] }, { "title": "Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1988", "authors": "Lamond AI, Konarska MM, Grabowski PJ, Sharp PA", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "2963332", "url": "https://glygen.org/publication/PubMed/2963332" } ] }, { "title": "Structures of the human pre-catalytic spliceosome and its precursor spliceosome.", "journal": "Cell research", "date": "2018", "authors": "Zhan X, Yan C, Zhang X, Lei J, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "30315277", "url": "https://glygen.org/publication/PubMed/30315277" } ] }, { "title": "A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.", "journal": "Science (New York, N.Y.)", "date": "2019", "authors": "Fica SM, Oubridge C, Wilkinson ME, Newman AJ, Nagai K", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "30705154", "url": "https://glygen.org/publication/PubMed/30705154" } ] }, { "title": "Structures of the human spliceosomes before and after release of the ligated exon.", "journal": "Cell research", "date": "2019", "authors": "Zhang X, Zhan X, Yan C, Zhang W, Liu D, Lei J, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "30728453", "url": "https://glygen.org/publication/PubMed/30728453" } ] }, { "title": "Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes.", "journal": "Cold Spring Harbor perspectives in biology", "date": "2019", "authors": "Kastner B, Will CL, Stark H, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "30765414", "url": "https://glygen.org/publication/PubMed/30765414" } ] }, { "title": "Mechanism of 5' splice site transfer for human spliceosome activation.", "journal": "Science (New York, N.Y.)", "date": "2019", "authors": "Charenton C, Wilkinson ME, Nagai K", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "30975767", "url": "https://glygen.org/publication/PubMed/30975767" } ] }, { "title": "Paralog Studies Augment Gene Discovery: DDX and DHX Genes.", "journal": "American journal of human genetics", "date": "2019", "authors": "Paine I, Posey JE, Grochowski CM, Jhangiani SN, Rosenheck S, Kleyner R, Marmorale T, Yoon M, Wang K, Robison R, Cappuccio G, Pinelli M, Magli A, Coban Akdemir Z, Hui J, Yeung WL, Wong BKY, Ortega L, Bekheirnia MR, Bierhals T, Hempel M, Johannsen J, Santer R, Aktas D, Alikasifoglu M, Bozdogan S, Aydin H, Karaca E, Bayram Y, Ityel H, Dorschner M, White JJ, Wilichowski E, Wortmann SB, Casella EB, Kitajima JP, Kok F, Monteiro F, Muzny DM, Bamshad M, Gibbs RA, Sutton VR, Van Esch H, Brunetti-Pierri N, Hildebrandt F, Brautbar A, Van den Veyver IB, Glass I, Lessel D, Lyon GJ, Lupski JR", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" } ], "reference": [ { "type": "PubMed", "id": "31256877", "url": "https://glygen.org/publication/PubMed/31256877" } ] }, { "title": "Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release.", "journal": "The Biochemical journal", "date": "2019", "authors": "Felisberto-Rodrigues C, Thomas JC, McAndrew C, Le Bihan YV, Burke R, Workman P, van Montfort RLM", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "31409651", "url": "https://glygen.org/publication/PubMed/31409651" } ] }, { "title": "Structural basis for DEAH-helicase activation by G-patch proteins.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "Studer MK, Ivanovic L, Weber ME, Marti S, Jonas S", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "32179686", "url": "https://glygen.org/publication/PubMed/32179686" } ] }, { "title": "Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.", "journal": "Nucleic acids research", "date": "2020", "authors": "Busetto V, Barbosa I, Basquin J, Marquenet E, Hocq R, Hennion M, Paternina JA, Namane A, Conti E, Bensaude O, Le Hir H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "32329775", "url": "https://glygen.org/publication/PubMed/32329775" } ] }, { "title": "Molecular architecture of the human 17S U2 snRNP.", "journal": "Nature", "date": "2020", "authors": "Zhang Z, Will CL, Bertram K, Dybkov O, Hartmuth K, Agafonov DE, Hofele R, Urlaub H, Kastner B, Luhrmann R, Stark H", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "32494006", "url": "https://glygen.org/publication/PubMed/32494006" } ] }, { "title": "Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.", "journal": "Science (New York, N.Y.)", "date": "2020", "authors": "Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "33243851", "url": "https://glygen.org/publication/PubMed/33243851" } ] }, { "title": "Structure of a transcribing RNA polymerase II-U1 snRNP complex.", "journal": "Science (New York, N.Y.)", "date": "2021", "authors": "Zhang S, Aibara S, Vos SM, Agafonov DE, Luhrmann R, Cramer P", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "33446560", "url": "https://glygen.org/publication/PubMed/33446560" } ] }, { "title": "Structure of the activated human minor spliceosome.", "journal": "Science (New York, N.Y.)", "date": "2021-03-19", "authors": "Bai Rui, Wan Ruixue, Wang Lin, Xu Kui, Zhang Qiangfeng, Lei Jianlin, Shi Yigong", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "reference": [ { "type": "PubMed", "id": "33509932", "url": "https://glygen.org/publication/PubMed/33509932" } ] }, { "title": "O-GlcNAc modification regulates MTA1 transcriptional activity during breast cancer cell genotoxic adaptation.", "journal": "Biochimica et biophysica acta. General subjects", "date": "2021", "authors": "Xie X, Wu Q, Zhang K, Liu Y, Zhang N, Chen Q, Wang L, Li W, Zhang J, Liu Y", "evidence": [ { "database": "O-GlcNAc Database", "id": "O60231", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60231" } ], "reference": [ { "type": "PubMed", "id": "34019948", "url": "https://glygen.org/publication/PubMed/34019948" } ] }, { "title": "Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.", "journal": "Nature communications", "date": "2021", "authors": "Cretu C, Gee P, Liu X, Agrawal A, Nguyen TV, Ghosh AK, Cook A, Jurica M, Larsen NA, Pena V", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "34301950", "url": "https://glygen.org/publication/PubMed/34301950" } ] }, { "title": "Truncation of the TPR domain of OGT alters substrate and glycosite selection.", "journal": "Analytical and bioanalytical chemistry", "date": "2021", "authors": "Ramirez DH, Yang B, D'Souza AK, Shen D, Woo CM", "evidence": [ { "database": "O-GlcNAc Database", "id": "O60231", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60231" } ], "reference": [ { "type": "PubMed", "id": "34725712", "url": "https://glygen.org/publication/PubMed/34725712" } ] }, { "title": "Structural basis of branch site recognition by the human spliceosome.", "journal": "Science (New York, N.Y.)", "date": "2022", "authors": "Tholen J, Razew M, Weis F, Galej WP", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "34822310", "url": "https://glygen.org/publication/PubMed/34822310" } ] }, { "title": "The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.", "journal": "Cell reports", "date": "2022", "authors": "Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, Garcia-Sastre A, Shi PY, Freiberg AN, Rajsbaum R", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" }, { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" } ], "reference": [ { "type": "PubMed", "id": "35263596", "url": "https://glygen.org/publication/PubMed/35263596" } ] }, { "title": "Retinitis pigmentosa-linked mutation in DHX38 modulates its splicing activity.", "journal": "PloS one", "date": "2022", "authors": "Obuca M, Cvackova Z, Kubovciak J, Kolar M, Stanek D", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "35385551", "url": "https://glygen.org/publication/PubMed/35385551" } ] }, { "title": "A compensatory base change in U1 snRNA suppresses a 5' splice site mutation.", "journal": "Cell", "date": "1986", "authors": "Zhuang Y, Weiner AM", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "3757028", "url": "https://glygen.org/publication/PubMed/3757028" } ] }, { "title": "Infantile onset encephalomyopathy, retinopathy, optic atrophy, and mitochondrial DNA depletion associated with a novel pathogenic DHX16 variant.", "journal": "Clinical genetics", "date": "2023-08-13", "authors": "Hautakangas Milla-Riikka, Widgren Paula, Korpelainen Paavo, Kangas Salla M, Komulainen Tuomas, Vieira P\u00e4ivi, Rahikkala Elisa, Pylk\u00e4s Katri, Tuominen Hannu, Kokkonen Hannaleena, Miinalainen Ilkka, Nadaf Javad, Majewski Jacek, Hinttala Reetta, Uusimaa Johanna", "evidence": [ { "database": "RefSeq", "id": "NP_001157711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157711" } ], "reference": [ { "type": "PubMed", "id": "37574199", "url": "https://glygen.org/publication/PubMed/37574199" } ] }, { "title": "Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A.", "journal": "Genes & development", "date": "1996", "authors": "Gozani O, Feld R, Reed R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "8566756", "url": "https://glygen.org/publication/PubMed/8566756" } ] }, { "title": "A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.", "journal": "Genes & development", "date": "1996", "authors": "Ohno M, Shimura Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "8608946", "url": "https://glygen.org/publication/PubMed/8608946" } ] }, { "title": "Association of U2 snRNP with the spliceosomal complex E.", "journal": "Nucleic acids research", "date": "1997", "authors": "Hong W, Bennett M, Xiao Y, Feld Kramer R, Wang C, Reed R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9016565", "url": "https://glygen.org/publication/PubMed/9016565" } ] }, { "title": "U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction.", "journal": "Genes & development", "date": "1997", "authors": "Fleckner J, Zhang M, Valcarcel J, Green MR", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9242493", "url": "https://glygen.org/publication/PubMed/9242493" } ] }, { "title": "A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition.", "journal": "Genes & development", "date": "1998", "authors": "Berglund JA, Abovich N, Rosbash M", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9512519", "url": "https://glygen.org/publication/PubMed/9512519" } ] }, { "title": "Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing.", "journal": "The EMBO journal", "date": "1998", "authors": "Zhou Z, Reed R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9524131", "url": "https://glygen.org/publication/PubMed/9524131" } ] }, { "title": "The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1998", "authors": "Laggerbauer B, Achsel T, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9539711", "url": "https://glygen.org/publication/PubMed/9539711" } ] }, { "title": "Cloning and characterization of a human DEAH-box RNA helicase, a functional homolog of fission yeast Cdc28/Prp8.", "journal": "Nucleic Acids Res.", "date": "1998", "authors": "Imamura O, Saiki K, Tani T, Ohshima Y, Sugawara M, Furuichi Y", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "reference": [ { "type": "PubMed", "id": "9547260", "url": "https://glygen.org/publication/PubMed/9547260" } ] }, { "title": "A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Gozani O, Potashkin J, Reed R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9671485", "url": "https://glygen.org/publication/PubMed/9671485" } ] }, { "title": "The mammalian homologue of Prp16p is overexpressed in a cell line tolerant to Leflunomide, a new immunoregulatory drug effective against rheumatoid arthritis.", "journal": "RNA (New York, N.Y.)", "date": "1998", "authors": "Ortlepp D, Laggerbauer B, Mullner S, Achsel T, Kirschbaum B, Luhrmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9701291", "url": "https://glygen.org/publication/PubMed/9701291" } ] }, { "title": "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.", "journal": "Nature genetics", "date": "1998", "authors": "Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M", "evidence": [ { "database": "Reactome", "id": "R-HSA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163" } ], "reference": [ { "type": "PubMed", "id": "9731529", "url": "https://glygen.org/publication/PubMed/9731529" } ] } ], "pathway": [ { "id": "hsa:8449", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:8449", "resource": "KEGG Pathway" }, { "id": "R-HSA-72163", "name": "mRNA Splicing - Major Pathway", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3X8X0-1", "protein_name": "RNA helicase", "gene_name": "Dhx16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPAGLERWVQEELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDTDTLDLGGPARDFALKLWSKVPRKAVVEKPARAAEREARALLEKNRSYKLLEDSESGEEAVGSNGSSLQKKRKRRKHLRKKHQEDEEDEEEEVSESGKRKAGGSKSPTEEKPASEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEVLFGDVELSRHERRELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARTVDIVEEESGAPGEEQRRWEEAQLGAASLKFGARDAAAQEAKYQLVLEEDETIEFVRAAQLQGDEEPSGPPLSAQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLTSCQGDYVRVRKAITSGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKVGKTREELG", "length": 1044 }, "evidence": [ { "id": "45924344", "url": "http://www.informatics.jax.org/homology/45924344", "database": "MGI" }, { "id": "O60231", "url": "https://omabrowser.org/oma/group/O60231/", "database": "OMA" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20095-1", "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2", "gene_name": "PRP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSITSETGKRRVKRTYEVTRQNDNAVRIEPSSLGEEEDKEAKDKNSALQLKRSRYDPNKVFSNTNQGPEKNNLKGEQLGSQKKSSKYDEKITSNNELTTKKGLLGDSENETKYASSNSKFNVEVTHKIKNAKEIDKINRQRMWEEQQLRNAMAGQSDHPDDITLEGSDKYDYVFDTDAMIDYTNEEDDLLPEEKLQYEARLAQALETEEKRILTIQEARKLLPVHQYKDELLQEIKKNQVLIIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARVADEMNVVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLATDILIGLLKDILPQRPTLKLLISSATMNAKKFSEFFDNCPIFNVPGRRYPVDIHYTLQPEANYIHAAITTIFQIHTTQSLPGDILVFLTGQEEIERTKTKLEEIMSKLGSRTKQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVGPGKCFRIFTKWSYLHELELMPKPEITRTNLSNTVLLLLSLGVTDLIKFPLMDKPSIPTLRKSLENLYILGALNSKGTITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIVSMLHETPSLFIGQKRDAAASVLSEVESDHILYLEIFNQWRNSKFSRSWCQDHKIQFKTMLRVRNIRNQLFRCSEKVGLVEKNDQARMKIGNIAGYINARITRCFISGFPMNIVQLGPTGYQTMGRSSGGLNVSVHPTSILFVNHKEKAQRPSKYVLYQQLMLTSKEFIRDCLVIPKEEWLIDMVPQIFKDLIDDKTNRGRR", "length": 876 }, "evidence": [ { "id": "O60231", "url": "https://omabrowser.org/oma/group/O60231/", "database": "OMA" } ], "common_name": "Yeast" }, { "uniprot_canonical_ac": "Q6MG13-1", "protein_name": "RNA helicase", "gene_name": "Dhx16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATPAGLERWVQEELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDTETLDLGGPARDFALKLWSKVPRKAVVEKPARAAEREARALLEKNRSYKLLEDSESGEEAVARDGSSLQKKRKRRKHLRKKQQEEEEEEEEASESGKRKTGGSKSPTEEKPASEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEVLFGDVELSRHERRELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARATDIVEEESGAPGEEQRRWEEARLDAASLKFGARDAAAQEPQYQLVLEEDETIEFVRAAQLQGDEEPSSGPPLSAQAQQKESIQAVRRSLPVFPFREELLTAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLTSCQGDYVRVRKAITSGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKVGKTREELG", "length": 1044 }, "evidence": [ { "id": "45924344", "url": "http://www.informatics.jax.org/homology/45924344", "database": "MGI" }, { "id": "O60231", "url": "https://omabrowser.org/oma/group/O60231/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q767K6-1", "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "gene_name": "DHX16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDTDTLDLSGPARDFALKLWNKVPRKAVAEKPARAAEREARALLEKNRSYRLLEDSEESSEEAVGRAGSSLQKKRKKRKHLRKKRQEEEEEEEEEEVPEKGKKTTGGNKPQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERRELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPEETRGQPTRAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPAAPPAPTQAQQKESIQAVRRSLPVFPFREELLAAVANHQILIIEGETGSGKTTQIPQYLFEEGYTQKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEEQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKTGKTREELG", "length": 1045 }, "evidence": [ { "id": "O60231", "url": "https://omabrowser.org/oma/group/O60231/", "database": "OMA" } ], "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9VIZ3-1", "protein_name": "RNA helicase", "gene_name": "l(2)37Cb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGKNRKRTASSSSSGEEPDSEEESRLKDLQERDEFASRLKKRDDDRTRNVVDSTGGRRAIEEATKRLKLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLLNIAKEHEKARELERIQRYNMPQDLKKGERSEYVEVDEFEKQPNSEQKKWEAEQLASARFHFGAKDAKAEEEYELLLDDQIDFIQALTLDGSREKSSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELEDSTNKKMPKVAGRAEMAQ", "length": 894 }, "evidence": [ { "id": "O60231", "url": "https://omabrowser.org/oma/group/O60231/", "database": "OMA" } ], "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "O60231", "url": "https://www.uniprot.org/uniprot/O60231" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + H(+) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3ZD32-1", "A0A8I5ZKX7-1", "D4A7Q5-1", "D4A523-1", "Q3MHU3-1", "Q6AYJ1-1", "F1M298-1", "Q5RJZ1-1", "P60123-1", "Q793F9-1", "F1LPQ2-1", "G3V681-1", "D4ACP5-1", "F1LNJ2-1", "D4A2Z8-1", "Q6P3V8-1", "Q5RKI1-1", "A0A0G2K0E0-1", "G3V9M1-1", "P70486-1", "Q66HG7-1", "Q99PT0-1", "D3ZG52-1", "Q4G005-1", "Q5BJS0-1", "Q64060-1", "Q9JIX5-1", "P06761-1", "Q5U216-1", "Q62780-1", "Q641Y8-1", "Q5XI69-1", "Q63413-1", "Q1HG60-1", "D3ZA12-1", "D3Z9Z9-1", "Q68G38-1", "Q6GX84-1", "Q9QUL6-1", "Q3B8Q2-1", "Q5EBA1-1", "P46462-1", "D3ZVK1-1", "Q9QY16-1", "A0A8I5ZZZ0-1", "A0A0G2K0H9-1", "Q62724-1", "Q3B8Q1-1", "G3V8T5-1", "Q9EQN5-1", "F1M9L4-1", "F1M5F3-1", "D3ZFP4-1", "D3ZP96-1", "D3ZHW0-1", "F1MA70-1", "D3ZX56-1", "Q5XIR6-1", "D3ZBY5-1", "Q8CG07-1", "B2GUX3-1", "P08289-1", "A0A8I6AFW4-1", "Q9WTT2-1", "Q5XI46-1", "A0A0G2KA92-1", "A0A8I5ZKV9-1", "E9PU01-1", "D4AAG9-1", "A0A0G2K283-1", "A0A096MJV7-1", "A0A0G2JTM6-1", "A0A8I5ZKH1-1", "D3ZSV6-1", "D3ZUC2-1", "D3ZD46-1", "A0A8I6GIY0-1", "G3V6W5-1", "D3ZD97-1", "A0A8I6ABZ7-1", "D3ZAP7-1", "D3ZQW1-1", "F1LTH9-1", "D3ZEG9-1", "D4A321-1", "Q6MG13-1", "P62738-1", "P63259-1", "P68035-1", "P68136-1", "P60711-1", "P63269-1", "P56536-1", "P54777-1", "P63018-1", "P82995-1", "D4A6Q6-1", "D4ADT5-1", "A0A8I6GIN4-1", "A6KSS8-1", "D4A2B7-1", "A0A8I6AK63-1", "A0A0G2K4S4-1", "A0A8I6GF11-1", "D3ZH42-1", "F1LWY1-1", "F1LTR3-1", "D4A1R0-1", "P97687-1", "Q5H9U9-1", "Q9Y265-1", "Q8IY21-1", "Q8NHQ9-1", "Q13206-1", "P33992-1", "P33991-1", "P46100-1", "Q4VNC0-1", "Q9Y4B4-1", "Q4VNC1-1", "Q8N3C0-1", "P54132-1", "O60306-1", "Q8TDI0-1", "Q3L8U1-1", "Q9P2D1-1", "Q9HCK8-1", "O14646-1", "O14647-1", "A8MPP1-1", "Q12873-1", "Q14839-1", "Q9Y230-1", "Q8TD26-1", "P49736-1", "O00148-1", "Q9UJV9-1", "P19447-1", "Q96GQ7-1", "Q9H8H2-1", "Q9BQ39-1", "Q9NXZ2-1", "Q9NY93-1", "Q9UMR2-1", "Q9NUU7-1", "Q13838-1", "P51530-1", "Q7Z478-1", "P17844-1", "Q7L7V1-1", "Q8IX18-1", "Q9H5Z1-1", "Q9H6R0-1", "Q9Y6V7-1", "Q9H0S4-1", "Q14147-1", "Q6P158-1", "Q92771-1", 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"P63260-1", "P62737-1", "P68134-1", "P54279-1", "P28738-1", "E9Q555-1", "P68033-1", "Q5BL07-1", "Q9EPU0-1", "A0A7N9VSG0-1", "Q6NZR5-1", "Q8CIW5-1", "Q6NZL1-1", "P55772-1", "Q8CGS6-1", "Q0VGT4-1", "P61222-1", "E9QAM5-1", "P15424-1", "P15938-1", "P16474-1", "P16521-1", "P20095-1", "P20447-1", "P20448-1", "P20449-1", "P21372-1", "P22516-1", "P23394-1", "P24004-1", "P24279-1", "P24384-1", "P24783-1", "P25808-1", "P29496-1", "P32863-1", "P33760-1", "P35187-1", "P35207-1", "P38132-1", "P38859-1", "P39517-1", "Q03532-1", "Q03940-1", "Q12464-1", "P06634-1", "P06839-1", "P07271-1", "P0CS90-1", "P10081-1", "P11484-1", "P12954-1", "P24784-1", "P25694-1", "P29469-1", "P32597-1", "P32644-1", "P53131-1", "P60010-1", "Q04437-1", "Q05931-1", "Q06218-1", "P30665-1", "P30771-1", "P31380-1", "P32580-1", "P32639-1", "P32794-1", "P32807-1", "P32892-1", "P0CX15-1", "P0CX21-1", "P34243-1", "O13559-1", "P0CX14-1", "P0CX20-1", "P36120-1", "P53978-1", "Q00578-1", "P38712-1", "P38766-1", "P40024-1", "P40150-1", "P40562-1", "P45818-1", "P51979-1", "P53115-1", "P53166-1", "P53327-1", "Q04217-1", "P36009-1", "Q05471-1", "P36016-1", "P38112-1", "P38719-1", "P40352-1", "P47047-1", "P53091-1", "P53734-1", "Q12389-1", "P38086-1", "Q05549-1", "Q07478-1", "Q12039-1", "Q12099-1", "Q12697-1", "P43538-1", "P0CX22-1", "P40105-1", "P40434-1", "P40889-1", "P53819-1", "Q03099-1", "Q06698-1", "Q07888-1", "Q99208-1", "Q08995-1", "Q3E7X8-1", "P17119-1", "P90529-1", "Q869Z1-1", "Q54KG8-1", "Q55F84-1", "Q54DN9-1", "Q54HE9-1", "Q54HF0-1", "Q54HF1-1", "Q54L54-1", "Q54LI7-1", "Q54NW5-1", "Q54P22-1", "Q54XQ3-1", "Q55CU2-1", "Q54VI9-1", "Q553B1-1", "Q54EC2-1", "Q54F05-1", "Q54G57-1", "Q54GX5-1", "Q54HE7-1", "Q54IV3-1", "Q54KG1-1", "Q54NJ4-1", "Q54Q94-1", "Q54QS3-1", "Q54RU0-1", "Q54S03-1", "Q54TD7-1", "Q54TJ4-1", "Q54VF1-1", "Q54VT4-1", "Q54Y81-1", "Q54ZI9-1", "Q554S6-1", "Q55A06-1", "Q55BR9-1", "Q55D61-1", "Q55EU6-1", "Q55F23-1", "Q55FJ4-1", "Q55GK2-1", "Q75JU2-1", "Q869P0-1", "Q86IF1-1", "Q86IZ9-1", "Q75JA0-1", "P07828-1", "Q54CD8-1", "B0G0Y4-1", "O00835-1", "P07829-1", "P07830-1", "Q54BD6-1", "Q54C21-1", "Q54C28-1", "Q54CD6-1", "Q54CE0-1", "Q54CP4-1", "Q54CS8-1", "Q54DG0-1", "Q54DM3-1", "Q54E49-1", "Q54GX7-1", "Q54I89-1", "Q54MA9-1", "Q54MH3-1", "Q54PT2-1", "Q54TF8-1", "Q54UW5-1", "Q54X63-1", "Q54Z42-1", "Q553U6-1", "Q55CP6-1", "Q55G81-1", "Q75JI3-1", "Q86B14-1", "O46072-1", "P23128-1", "P25439-1", "P26802-1", "Q02748-1", "Q26454-1", "Q6J5K9-1", "Q9GQN5-1", "Q9VD51-1", "Q9VL72-1", "Q9VNP5-1", "Q7KN62-1", "Q9V3K3-1", "Q9VF26-1", "Q9VH07-1", "Q9VL52-1", "P49735-1", "Q9V461-1", "Q9VGW6-1", "Q9VDY1-1", "Q7K3M5-1", "P09052-1", "Q9VN03-1", "Q9W484-1", "Q9VGI8-1", "Q9VHS8-1", "Q9VUV9-1", "Q9VYS3-1", "Q9VSE2-1", "Q9VIF6-1", "Q9VVK8-1", "Q9V3C4-1", "O61305-1", "Q9VX34-1", "Q9VRI0-1", "Q9VJ74-1", "Q6NQY9-1", "Q9W3Y5-1", "Q7KU24-1", "Q02870-1", "Q07886-1", "Q23976-1", "Q27268-1", "Q9V3C0-1", "Q9VHP0-1", "Q9VHU1-1", "Q9VNV3-1", "Q9VQN8-1", "P24785-1", "P46461-1", "P54351-1", "Q86B47-1", "A8DZ26-1", "P19109-1", "P29844-1", "Q9V433-1", "Q7KVP9-1", "A1Z9L3-1", "O16102-1", "O97159-1", "Q9XYU0-1", "Q9XYU1-1", "Q9I7M8-1", "Q9VL25-1", "Q9VY54-1", "Q8SWT2-1", "Q8IRL9-1", "Q8ING5-1", "Q8SY39-1", "Q9VPT3-1", "P10987-1", "P10981-1", "P20480-1", "Q9VQR3-1", "P53501-1", "P02572-1", "P83967-1", "P02574-1", "Q9VIZ3-1", "Q9VL76-1", "Q9VDA0-1", "Q9W4W2-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-HSA-9770131", "name": "Formation of the Spliceosomal B* complex", "equation": "", "summary": "DHX16 (homolog of yeast Prp2) hydrolyzes ATP in the Spliceosomal Bact complex to form the Spliceosomal B* complex (Gencheva et al. 2010), possibly by pulling the intron to dissociate the RES complex and the SF3A and SF3B subcomplexes of the U2 snRNP from the spliceosome (Bessonov et al. 2010, Agafonov et al. 2011, Schmidt et al. 2014, Kastner et al. 2019). The intron branch point now docks near the 5' splice site (Zhan et al. 2018), displacing RNF113A (homolog of yeast Cwc24) (Schmidt et al. 2014, Zhan et al. 2018). YJU2 and ISY1 bind and distort the helix of the branch point to fit the active site (Zhan et al. 2018). Prior to the transesterification reaction between the adenosine residue of the intron branch point and the 5' splice site, the complex is called the Spliceosomal B* complex.
Components of the core exon junction complex (EJC) comprising EIF4A3, CASC3, MAGOH, and RBM8A are recruited to the spliceosome around this time (Kataoka and Dreyfuss 2004) by an interaction between CWC22 and EIF4A3 (Reichert et al. 2002, Alexandrov et al. 2012, Barbosa et al. 2012, Steckelberg et al. 2012, Busetto et al. 2020), though they may not yet bind RNA. CWC27 must be displaced in order for RBM8A (Y14) to bind (Busetto et al. 2020). Due to the position of CWC22 in the spliceosome, the EJC will be deposited on the 5' exon about 20-24 nucleotides upstream of the 5' splice site. The components and formation of the spliceosomal B* complex are partly inferred from the composition of the spliceosomal C complex (Jurica et al. 2002, Makarov et al. 2002, Rappsilber et al. 2002, Reichert et al. 2002, Bessonov et al. 2010, Agafonov et al. 2011, Schmidt et al. 2014, Zhan et al. 2018, Kastner et al. 2019).", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-HSA-156776", "R-HSA-72060", "R-HSA-8849148", "R-HSA-8867884", "R-HSA-8867893", "R-HSA-8867898", "R-HSA-8952113", "R-HSA-9769592", "R-HSA-9770419", "R-HSA-9770425", "R-HSA-9770427", "R-HSA-9770428", "R-HSA-9770430" ], "output_participant_list": [ "R-HSA-2396419", "R-HSA-71967", "R-HSA-71976" ], "enzyme_list": [ "O75643-1", "Q86XP3-1", "Q13356-1", "Q96BP3-1", "Q9H2H8-1", "O15541-1", "P11142-1", "P24928-1", "O60306-1", "Q9UNP9-1", "P38919-1", "Q13838-1", "Q9Y3C6-1", "Q8WUA2-1", "Q13427-1", "Q7L014-1", "P30876-1", "O60231-1", "Q92620-1", "P42285-1", "P17844-1", "O43143-1", "Q9H5Z1-1", "Q9UMS4-1" ], "evidence": [ { "id": "R-HSA-9770131", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9770131" } ] }, { "id": "R-HSA-9770145", "name": "Formation of the Spliceosomal Bact complex", "equation": "", "summary": "Activation of the Spliceosomal B complex to form the Spliceosomal Bact complex is believed to occur in several complex steps. SNRNP200 (homolog of yeast Brr2) of the U5 snRNP uses ATP to dissociate the U4 snRNP from the spliceosome. This renders U6 snRNA free to form additional interactions with U2 snRNA and fold its internal stem loop to create the active site (Laggerbauer et al. 1998, Lamond et al. 1988, Bessonov et al. 2010, Agafonov et al. 2011, Fica et al. 2013, Galej et al. 2016, Haselbach et al. 2018, Zhang et al. 2018, Kastner et al. 2019). In this active site four phosphate groups of the U6 snRNA cooridinate the two magnesium ions that catalyze both transesterification reactions of pre-mRNA splicing..The PRP19-CDC5L complex (Ajuh et al. 2000, also called the NTC complex) and the PRP19-CDC5L related complex (also called the NTR complex) are recruited during this transition and stabilize the active site (Bessonov et al. 2010, Agafonov et al. 2011, Haselbach et al. 2018, Zhang et al. 2018, Kastner et al. 2019). Splicing does not yet occur because the SF3B1 subunit of the U2 snRNP blocks the branch point and SF3A2 and RNF113A protect the 5' splice site, preventing the intron branch point from reacting with the 5' splice site (Gozani et al. 1996, Gozani et al. 1998, Haselbach et al. 2018, Zhang et al. 2018, Tholen et al. 2022). SNRNP200 and the RES complex retain the SF3B subcomplex in the spliceosome (Haselbach et al. 2018, Zhang et al. 2018). CWC22 recruits EIF4A3, which will form the exon junction complex (EJC) (Busetto et al. 2020) . The components of the Spliceosomal Bact complex have been ascertained using proteomic and structural methods (Bessonov et al. 2010, Agafonov et al. 2011, Haselbach et al. 2018, Zhang et al. 2018, Kastner et al. 2019, Townsend et al. 2020).", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-HSA-8849149", "R-HSA-8850837", "R-HSA-8850839", "R-HSA-8865956", "R-HSA-8867885", "R-HSA-8867892", "R-HSA-8952110", "R-HSA-9769561", "R-HSA-9769562", "R-HSA-9769563" ], "output_participant_list": [ "R-HSA-3246027", "R-HSA-53517", "R-HSA-71875", "R-HSA-71881" ], "enzyme_list": [ "O75643-1", "Q86XP3-1", "Q13356-1", "Q9H2H8-1", "O15541-1", "P11142-1", "Q08211-1", "P24928-1", "O60306-1", "Q9UNP9-1", "P38919-1", "Q13838-1", "Q9Y3C6-1", "Q7L014-1", "P30876-1", "O60231-1", "Q9BUQ8-1", "P42285-1", "P17844-1", "O43143-1", "Q9UMS4-1", "O43447-1" ], "evidence": [ { "id": "R-HSA-9770145", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9770145" } ] } ], 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H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "B2GUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUX3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "B2GUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUX3" } ] } ] }, { "uniprot_ac": "B2RR83", "gene_name": "Ythdc2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "B2RR83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RR83" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "B2RR83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RR83" } ] } ] }, { "uniprot_ac": "D3Z0M9", "gene_name": "Ddx23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3Z0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3Z0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ] } ] }, { "uniprot_ac": "D3Z4R1", "gene_name": "Hfm1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3Z4R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z4R1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3Z4R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z4R1" } ] } ] }, { "uniprot_ac": "D3Z9Z9", "gene_name": "Smarcad1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3Z9Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z9Z9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3Z9Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z9Z9" } ] } ] }, { "uniprot_ac": "D3ZA12", "gene_name": "Chd6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZA12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZA12" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZA12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZA12" } ] } ] }, { "uniprot_ac": "D3ZAP7", "gene_name": "Chd7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZAP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZAP7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZAP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZAP7" } ] } ] }, { "uniprot_ac": "D3ZBY5", "gene_name": "Ddx10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZBY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBY5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZBY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBY5" } ] } ] }, { "uniprot_ac": "D3ZD32", "gene_name": "Chd5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD32" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD32" } ] } ] }, { "uniprot_ac": "D3ZD46", "gene_name": "Dhx58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZD46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD46" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZD46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD46" } ] } ] }, { "uniprot_ac": "D3ZD97", "gene_name": "Dhx15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD97" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD97" } ] } ] }, { "uniprot_ac": "D3ZEG9", "gene_name": "Ercc2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZEG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEG9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZEG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEG9" } ] } ] }, { "uniprot_ac": "D3ZFP4", "gene_name": "Mcm3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZFP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFP4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZFP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFP4" } ] } ] }, { "uniprot_ac": "D3ZG52", "gene_name": "Dna2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "D3ZG52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG52" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZG52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG52" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZG52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG52" } ] } ] }, { "uniprot_ac": "D3ZH42", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZH42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZH42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZH42" } ] } ] }, { "uniprot_ac": "D3ZHW0", "gene_name": "Dhx29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHW0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHW0" } ] } ] }, { "uniprot_ac": "D3ZP96", "gene_name": "Mcm2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP96" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP96" } ] } ] }, { "uniprot_ac": "D3ZQW1", "gene_name": "Blm", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZQW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQW1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZQW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQW1" } ] } ] }, { "uniprot_ac": "D3ZSV6", "gene_name": "Dhx33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZSV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSV6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZSV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSV6" } ] } ] }, { "uniprot_ac": "D3ZUC2", "gene_name": "Mov10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZUC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZUC2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZUC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZUC2" } ] } ] }, { "uniprot_ac": "D3ZVK1", "gene_name": "Mcm8", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVK1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVK1" } ] } ] }, { "uniprot_ac": "D3ZX56", "gene_name": "Ddx55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZX56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZX56" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZX56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZX56" } ] } ] }, { "uniprot_ac": "D4A1R0", "gene_name": "Dhx37", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A1R0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A1R0" } ] } ] }, { "uniprot_ac": "D4A2B7", "gene_name": "Afg2b", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A2B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2B7" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "D4A2B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2B7" } ] } ] }, { "uniprot_ac": "D4A2Z8", "gene_name": "Dhx36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] } ] }, { "uniprot_ac": "D4A321", "gene_name": "Dhx38", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A321" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A321" } ] } ] }, { "uniprot_ac": "D4A523", "gene_name": "Nlrp3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "D4A523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A523" } ] } ] }, { "uniprot_ac": "D4A6Q6", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "D4A6Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6Q6" } ] } ] }, { "uniprot_ac": "D4A7Q5", "gene_name": "Ddx28", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A7Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7Q5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A7Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7Q5" } ] } ] }, { "uniprot_ac": "D4AAG9", "gene_name": "Chd1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4AAG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AAG9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D4AAG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AAG9" } ] } ] }, { "uniprot_ac": "D4ACP5", "gene_name": "Recql5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4ACP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACP5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D4ACP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACP5" } ] } ] }, { "uniprot_ac": "D4ADT5", "gene_name": "Rig1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4ADT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4ADT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT5" } ] } ] }, { "uniprot_ac": "E9PU01", "gene_name": "Chd4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "E9PU01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PU01" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E9PU01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PU01" } ] } ] }, { "uniprot_ac": "E9PZJ8", "gene_name": "Ascc3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "E9PZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PZJ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E9PZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PZJ8" } ] } ] }, { "uniprot_ac": "E9PZM4", "gene_name": "Chd2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "E9PZM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PZM4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E9PZM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PZM4" } ] } ] }, { "uniprot_ac": "E9Q555", "gene_name": "Rnf213", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "E9Q555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q555" } ] }, { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E9Q555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q555" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E9Q555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q555" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E9Q555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q555" } ] } ] }, { "uniprot_ac": "E9QAM5", "gene_name": "Helz2", "activity": [ { "ec_number": "3.1.13.1", "activity": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "E9QAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9QAM5" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "E9QAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9QAM5" } ] }, { "ec_number": "3.1.13.1", "activity": "", "evidence": [ { "id": "E9QAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9QAM5" } ] } ] }, { "uniprot_ac": "F1LNJ2", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1LNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ2" } ] } ] }, { "uniprot_ac": "F1LPQ2", "gene_name": "Ascc3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LPQ2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1LPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LPQ2" } ] } ] }, { "uniprot_ac": "F1LTH9", "gene_name": "Wrn", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTH9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1LTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTH9" } ] } ] }, { "uniprot_ac": "F1LTR3", "gene_name": "Tdrd12", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LTR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTR3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1LTR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTR3" } ] } ] }, { "uniprot_ac": "F1LWY1", "gene_name": "Hfm1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWY1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1LWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWY1" } ] } ] }, { "uniprot_ac": "F1M298", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "F1M298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M298" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1M298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M298" } ] } ] }, { "uniprot_ac": "F1M5F3", "gene_name": "Mcm9", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1M5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M5F3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1M5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M5F3" } ] } ] }, { "uniprot_ac": "F1M9L4", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1M9L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9L4" } ] } ] }, { "uniprot_ac": "F1MA70", "gene_name": "Atp13a5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1MA70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1MA70" } ] } ] }, { "uniprot_ac": "F8VPZ5", "gene_name": "Ercc6", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F8VPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F8VPZ5" } ] } ] }, { "uniprot_ac": "G3V681", "gene_name": "Mcm4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V681" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "G3V681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V681" } ] } ] }, { "uniprot_ac": "G3V6W5", "gene_name": "Ifih1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6W5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3V6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6W5" } ] } ] }, { "uniprot_ac": "G3V8T5", "gene_name": "Ruvbl2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V8T5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "G3V8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V8T5" } ] } ] }, { "uniprot_ac": "G3V9M1", "gene_name": "Ddx23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V9M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V9M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3V9M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V9M1" } ] } ] }, { "uniprot_ac": "G3X8X0", "gene_name": "Dhx16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3X8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3X8X0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3X8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3X8X0" } ] } ] }, { "uniprot_ac": "O00148", "gene_name": "DDX39A", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O00148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00148" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O00148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00148" } ] } ] }, { "uniprot_ac": "O00571", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O00571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00571" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O00571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00571" } ] } ] }, { "uniprot_ac": "O00835", "gene_name": "repB", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O00835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00835" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O00835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00835" } ] } ] }, { "uniprot_ac": "O08811", "gene_name": "Ercc2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O08811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08811" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O08811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08811" } ] } ] }, { "uniprot_ac": "O09053", "gene_name": "Wrn", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O09053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09053" } ] }, { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "O09053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09053" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O09053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09053" } ] } ] }, { "uniprot_ac": "O13559", "gene_name": "YRF1-4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O13559", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13559" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O13559", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13559" } ] } ] }, { "uniprot_ac": "O14646", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O14646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14646" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O14646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14646" } ] } ] }, { "uniprot_ac": "O14647", "gene_name": "CHD2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O14647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14647" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O14647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14647" } ] } ] }, { "uniprot_ac": "O14656", "gene_name": "TOR1A", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O14656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14656" } ] } ] }, { "uniprot_ac": "O14657", "gene_name": "TOR1B", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O14657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14657" } ] } ] }, { "uniprot_ac": "O15523", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O15523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15523" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O15523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15523" } ] } ] }, { "uniprot_ac": "O15541", "gene_name": "RNF113A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "O15541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15541" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "O15541", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15541" } ] } ] }, { "uniprot_ac": "O16102", "gene_name": "Chd3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O16102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O16102" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O16102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O16102" } ] } ] }, { "uniprot_ac": "O35286", "gene_name": "Dhx15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O35286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35286" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O35286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35286" } ] } ] }, { "uniprot_ac": "O43143", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O43143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43143" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O43143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43143" } ] } ] }, { "uniprot_ac": "O43447", "gene_name": "PPIH", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "O43447", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43447" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "O43447", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43447" } ] } ] }, { "uniprot_ac": "O43933", "gene_name": "PEX1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O43933", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43933" } ] } ] }, { "uniprot_ac": "O46072", "gene_name": "kz", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O46072", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O46072" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O46072", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O46072" } ] } ] }, { "uniprot_ac": "O60231", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O60231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60231" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O60231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60231" } ] } ] }, { "uniprot_ac": "O60282", "gene_name": "KIF5C", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O60282", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60282" } ] } ] }, { "uniprot_ac": "O60306", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O60306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60306" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O60306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60306" } ] } ] }, { "uniprot_ac": "O61305", "gene_name": "Dbp80", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O61305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61305" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O61305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61305" } ] } ] }, { "uniprot_ac": "O70133", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O70133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70133" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O70133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70133" } ] } ] }, { "uniprot_ac": "O75351", "gene_name": "VPS4B", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O75351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75351" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "O75351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75351" } ] } ] }, { "uniprot_ac": "O75417", "gene_name": "POLQ", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O75417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75417" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O75417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75417" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O75417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75417" } ] } ] }, { "uniprot_ac": "O75643", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O75643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75643" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O75643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75643" } ] } ] }, { "uniprot_ac": "O88700", "gene_name": "Blm", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O88700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88700" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O88700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88700" } ] } ] }, { "uniprot_ac": "O94761", "gene_name": "RECQL4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O94761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94761" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O94761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94761" } ] } ] }, { "uniprot_ac": "O94762", "gene_name": "RECQL5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O94762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94762" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O94762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94762" } ] } ] }, { "uniprot_ac": "O95786", "gene_name": "RIGI", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O95786", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95786" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O95786", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95786" } ] } ] }, { "uniprot_ac": "O97159", "gene_name": "Mi-2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O97159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97159" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "O97159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97159" } ] } ] }, { "uniprot_ac": "P02572", "gene_name": "Act42A", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P02572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P02572" } ] } ] }, { "uniprot_ac": "P02574", "gene_name": "Act79B", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P02574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P02574" } ] } ] }, { "uniprot_ac": "P05186", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P05186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05186" } ] }, { "ec_number": "3.9.1.1", "activity": "H2O + N-phosphocreatine = creatine + phosphate.", "evidence": [ { "id": "P05186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05186" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P05186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05186" } ] }, { "ec_number": "3.9.1.1", "activity": "", "evidence": [ { "id": "P05186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05186" } ] } ] }, { "uniprot_ac": "P06634", "gene_name": "DED1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P06634", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06634" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P06634", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06634" } ] } ] }, { "uniprot_ac": "P06761", "gene_name": "Hspa5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P06761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06761" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P06761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06761" } ] } ] }, { "uniprot_ac": "P06839", "gene_name": "RAD3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P06839", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06839" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P06839", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06839" } ] } ] }, { "uniprot_ac": "P07271", "gene_name": "PIF1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P07271", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07271" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P07271", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07271" } ] } ] }, { "uniprot_ac": "P07828", "gene_name": "act18", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P07828", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07828" } ] } ] }, { "uniprot_ac": "P07829", "gene_name": "act3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P07829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07829" } ] } ] }, { "uniprot_ac": "P07830", "gene_name": "act19", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P07830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07830" } ] } ] }, { "uniprot_ac": "P07900", "gene_name": "HSP90AA1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P07900", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07900" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P07900", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07900" } ] } ] }, { "uniprot_ac": "P07901", "gene_name": "Hsp90aa1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P07901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07901" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P07901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07901" } ] } ] }, { "uniprot_ac": "P08289", "gene_name": "Alpl", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P08289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08289" } ] }, { "ec_number": "3.9.1.1", "activity": "H2O + N-phosphocreatine = creatine + phosphate.", "evidence": [ { "id": "P08289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08289" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P08289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08289" } ] } ] }, { "uniprot_ac": "P09052", "gene_name": "vas", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P09052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09052" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P09052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09052" } ] } ] }, { "uniprot_ac": "P09242", "gene_name": "Alpl", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09242" } ] }, { "ec_number": "3.9.1.1", "activity": "H2O + N-phosphocreatine = creatine + phosphate.", "evidence": [ { "id": "P09242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09242" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09242" } ] }, { "ec_number": "3.9.1.1", "activity": "", "evidence": [ { "id": "P09242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09242" } ] } ] }, { "uniprot_ac": "P0CS90", "gene_name": "SSC1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P0CS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CS90" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P0CS90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CS90" } ] } ] }, { "uniprot_ac": "P0CX14", "gene_name": "YRF1-3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P0CX14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX14" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P0CX14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX14" } ] } ] }, { "uniprot_ac": "P0CX15", "gene_name": "YRF1-7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P0CX15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX15" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P0CX15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX15" } ] } ] }, { "uniprot_ac": "P0CX20", "gene_name": "YRF1-1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P0CX20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX20" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P0CX20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX20" } ] } ] }, { "uniprot_ac": "P0CX21", "gene_name": "YRF1-5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P0CX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX21" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P0CX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX21" } ] } ] }, { "uniprot_ac": "P0CX22", "gene_name": "YRF1-8", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P0CX22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX22" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P0CX22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX22" } ] } ] }, { "uniprot_ac": "P10081", "gene_name": "TIF1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P10081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10081" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P10081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10081" } ] } ] }, { "uniprot_ac": "P10630", "gene_name": "Eif4a2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P10630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10630" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P10630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10630" } ] } ] }, { "uniprot_ac": "P10981", "gene_name": "Act87E", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P10981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10981" } ] } ] }, { "uniprot_ac": "P10987", "gene_name": "Act5C", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P10987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10987" } ] } ] }, { "uniprot_ac": "P11021", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P11021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11021" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P11021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11021" } ] } ] }, { "uniprot_ac": "P11142", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P11142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11142" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P11142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11142" } ] } ] }, { "uniprot_ac": "P11484", "gene_name": "SSB1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P11484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11484" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P11484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11484" } ] } ] }, { "uniprot_ac": "P12954", "gene_name": "SRS2", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "P12954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12954" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "P12954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12954" } ] } ] }, { "uniprot_ac": "P15424", "gene_name": "MSS116", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P15424", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15424" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P15424", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15424" } ] } ] }, { "uniprot_ac": "P15938", "gene_name": "PRP16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P15938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15938" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P15938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15938" } ] } ] }, { "uniprot_ac": "P16381", "gene_name": "D1Pas1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P16381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16381" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P16381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16381" } ] } ] }, { "uniprot_ac": "P16474", "gene_name": "KAR2", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P16474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16474" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P16474", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16474" } ] } ] }, { "uniprot_ac": "P16521", "gene_name": "YEF3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P16521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16521" } ] } ] }, { "uniprot_ac": "P17119", "gene_name": "KAR3", "activity": [ { "ec_number": "5.6.1.4", "activity": "ATP + H2O + a kinesin associated with a microtubule at position (n) = ADP + phosphate + a kinesin associated with a microtubule at position (n-1, toward the minus end).", "evidence": [ { "id": "P17119", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17119" } ] }, { "ec_number": "5.6.1.4", "activity": "", "evidence": [ { "id": "P17119", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17119" } ] } ] }, { "uniprot_ac": "P17844", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P17844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17844" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P17844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17844" } ] } ] }, { "uniprot_ac": "P18074", "gene_name": "ERCC2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P18074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18074" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P18074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18074" } ] } ] }, { "uniprot_ac": "P19109", "gene_name": "Rm62", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P19109", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19109" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P19109", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19109" } ] } ] }, { "uniprot_ac": "P19447", "gene_name": "ERCC3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P19447", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19447" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P19447", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19447" } ] } ] }, { "uniprot_ac": "P20029", "gene_name": "Hspa5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P20029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20029" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P20029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20029" } ] } ] }, { "uniprot_ac": "P20095", "gene_name": "PRP2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P20095", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20095" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "P20095", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20095" } ] } ] }, { "uniprot_ac": "P20447", "gene_name": "DBP3", "activity": [ { 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