{ "uniprot_canonical_ac": "O43854-1", "uniprot_ac": "O43854", "uniprot_id": "EDIL3_HUMAN", "mass": { "chemical_mass": 53765.0, "monoisotopic_mass": 53765.0 }, "refseq": { "ac": "NP_001265571", "name": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform 2 precursor", "summary": "The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior. 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Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" }, { "database": "PubMed", "id": "37627279", "url": "https://glygen.org/publication/PubMed/37627279" } ] }, { "annotation": "Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" }, { "database": "PubMed", "id": "19292890", "url": "https://glygen.org/publication/PubMed/19292890" } ] }, { "annotation": "Identification of a novel non-invasive biological marker to overcome the shortcomings of PSA in diagnosis and risk stratification for prostate cancer: Initial prospective study of developmental endothelial locus-1 protein. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" }, { "database": "PubMed", "id": "33901217", "url": "https://glygen.org/publication/PubMed/33901217" } ] }, { "annotation": "Obesity and altered angiogenic-related gene expression in endometrial cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" }, { "database": "PubMed", "id": "34538531", "url": "https://glygen.org/publication/PubMed/34538531" } ] }, { "annotation": "Observational study of gene-disease association. (HuGE Navigator)", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" }, { "database": "PubMed", "id": "19578876", "url": "https://glygen.org/publication/PubMed/19578876" } ] }, { "annotation": "Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "O43854", "url": "https://www.uniprot.org/uniprot/O43854#function" } ] }, { "annotation": "Regulatory role of local tissue signal Del-1 in cancer and inflammation: a review. 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"description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "O43854", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O43854" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", 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"https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O43854" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { "database": "BioXpress", "id": "O43854", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O43854" } ], "disease": [ { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "4D90", "url": "https://www.rcsb.org/structure/4D90", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00008", "url": "http://pfam.xfam.org/family/PF00008", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00754", "url": "http://pfam.xfam.org/family/PF00754", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12661", "url": "http://pfam.xfam.org/family/PF12661", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "O43854", "url": "https://pharos.nih.gov/targets/O43854", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR_O43854", "url": "http://purl.obolibrary.org/obo/PR_O43854", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "O43854", "url": "DISABLED", "database": "UniCarbKB", "categories": [ "Glycoproteomics" ] }, { "id": "O43854", "url": "https://www.uniprot.org/uniprot/O43854", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O43854-1", "url": "https://www.uniprot.org/uniprot/O43854-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O43854-2", "url": "https://www.uniprot.org/uniprot/O43854-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE", "length": 480, "header": 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"strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000296591.10", "url": "https://www.ensembl.org/id/ENST00000296591.10" }, { "database": "Ensembl Peptide", "id": "ENSP00000296591.4", "url": "https://www.ensembl.org/id/ENSP00000296591.4" } ] } }, { "isoform_ac": "O43854-2", "url": "", "sequence": { "sequence": "MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE", "length": 470, "header": "sp|O43854-2|EDIL3_HUMAN Isoform 2 of EGF-like repeat and discoidin I-like domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EDIL3 PE=1 SV=1 CANONICAL=O43854-1" }, "locus": { "chromosome": "5", "start_pos": 84384374, "end_pos": 83943422, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000380138.3", "url": "https://www.ensembl.org/id/ENST00000380138.3" }, { "database": "Ensembl Peptide", "id": "ENSP00000369483.3", "url": "https://www.ensembl.org/id/ENSP00000369483.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "reported", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 140, "start_aa": "Asn", "end_pos": 140, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn140", "evidence": [ { "id": "O43854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43854#ptm_processing" }, { "id": "22601780", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22601780" } ] }, { "glytoucan_ac": "G57321FI", "type": "O-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "SGHIQDYQITASSIFR", "relation": "attached", "comment": "Data provided by GlycoDomainViewer", "start_pos": 327, "start_aa": "Ser", "end_pos": 342, "end_aa": "Arg", "evidence": [ { "id": "O43854", "database": "UniCarbKB", "url": "" }, { "id": "23584533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23584533" }, { "id": "10.1038/emboj.2013.79", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1038/emboj.2013.79" } ] }, { "glytoucan_ac": "G57321FI", "type": "O-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "Data provided by GlycoDomainViewer", "start_pos": 336, "start_aa": "Thr", "end_pos": 336, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr336", "evidence": [ { "id": "O43854", "database": "UniCarbKB", "url": "" }, { "id": "23584533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23584533" }, { "id": "10.1038/emboj.2013.79", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1038/emboj.2013.79" } ] }, { "glytoucan_ac": "G57321FI", "type": "O-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "VTGIITQGAK", "relation": "attached", "comment": "Data provided by GlycoDomainViewer", "start_pos": 388, "start_aa": "Val", "end_pos": 397, "end_aa": "Lys", "evidence": [ { "id": "O43854", "database": "UniCarbKB", "url": "" }, { "id": "23584533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23584533" }, { "id": "10.1038/emboj.2013.79", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1038/emboj.2013.79" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GalNAcylation", "site_category": "reported", "site_seq": "T", "relation": "attached", "comment": "O-linked (GalNAc...) threonine O-GalNAcylation", "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "O43854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43854#ptm_processing" }, { "id": "22601780", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22601780" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-fucosylation", "site_category": "reported", "site_seq": "T", "relation": "attached", "comment": "O-linked (Fuc...) threonine O-fucosylation", "start_pos": 88, "start_aa": "Thr", "end_pos": 88, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr88", "evidence": [ { "id": "O43854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43854#ptm_processing" }, { "id": "22601780", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22601780" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "O43854", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O43854" }, { "id": "34725712", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34725712" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_reported" ], "publication": [ { "title": "Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology", "journal": "EMBO J", "date": "2013", "authors": "Steentoft C., Vakhrushev S.Y., Joshi H.J., Kong Y., Vester-Christensen M.B., Schjoldager K.T., Lavrsen K., Dabelsteen S., Pedersen N.B., Marcos-Silva L., Gupta R., Bennett E.P., Mandel U., Brunak S., Wandall H.H., Levery S.B., Clausen H.", "evidence": [ { "database": "UniCarbKB", "id": "O43854", "url": "" } ], "reference": [ { "type": "DOI", "id": "10.1038/emboj.2013.79", "url": "https://glygen.org/publication/DOI/10.1038/emboj.2013.79" } ] }, { "title": "The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation.", "journal": "Microvascular research", "date": "2002", "authors": "Aoka Y, Johnson FL, Penta K, Hirata Ki K, Hidai C, Schatzman R, Varner JA, Quertermous T", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "12074641", "url": "https://glygen.org/publication/PubMed/12074641" } ] }, { "title": "The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion.", "journal": "European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)", "date": "2007", "authors": "Niu JX, Zhang WJ, Ye LY, Wu LQ, Zhu GJ, Yang ZH, Grau GE, Lou JN", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "18090124", "url": "https://glygen.org/publication/PubMed/18090124" } ] }, { "title": "Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer.", "journal": "Journal of biomedical science", "date": "2009", "authors": "Zou X, Qiao H, Jiang X, Dong X, Jiang H, Sun X", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "19292890", "url": "https://glygen.org/publication/PubMed/19292890" } ] }, { "title": "The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.", "journal": "Human genetics", "date": "2009", "authors": "Johnson MP, Roten LT, Dyer TD, East CE, Forsmo S, Blangero J, Brennecke SP, Austgulen R, Moses EK", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "19578876", "url": "https://glygen.org/publication/PubMed/19578876" } ] }, { "title": "The RGD finger of Del-1 is a unique structural feature critical for integrin binding.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2012", "authors": "Schurpf T, Chen Q, Liu JH, Wang R, Springer TA, Wang JH", "evidence": [ { "database": "UniProtKB", "id": "O43854", "url": "https://www.uniprot.org/uniprot/O43854#ptm_processing" }, { "database": "UniProtKB", "id": "O43854", "url": "https://www.uniprot.org/uniprot/O43854" } ], "reference": [ { "type": "PubMed", "id": "22601780", "url": "https://glygen.org/publication/PubMed/22601780" } ] }, { "title": "Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.", "journal": "The EMBO journal", "date": "2013", "authors": "Steentoft C, Vakhrushev SY, Joshi HJ, Kong Y, Vester-Christensen MB, Schjoldager KT, Lavrsen K, Dabelsteen S, Pedersen NB, Marcos-Silva L, Gupta R, Bennett EP, Mandel U, Brunak S, Wandall HH, Levery SB, Clausen H", "evidence": [ { "database": "UniCarbKB", "id": "O43854", "url": "" } ], "reference": [ { "type": "PubMed", "id": "23584533", "url": "https://glygen.org/publication/PubMed/23584533" } ] }, { "title": "Identification of a novel non-invasive biological marker to overcome the shortcomings of PSA in diagnosis and risk stratification for prostate cancer: Initial prospective study of developmental endothelial locus-1 protein.", "journal": "PloS one", "date": "2021", "authors": "Chung JW, Kim HT, Ha YS, Lee EH, Chun SY, Lee CH, Byeon KH, Choi SH, Lee JN, Kim BS, Kim TH, Yoo ES, Yoon GS, Baek MC, Kwon TG", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "33901217", "url": "https://glygen.org/publication/PubMed/33901217" } ] }, { "title": "Regulatory role of local tissue signal Del-1 in cancer and inflammation: a review.", "journal": "Cellular & molecular biology letters", "date": "2021", "authors": "Li M, Zhong D, Li G", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "34217213", "url": "https://glygen.org/publication/PubMed/34217213" } ] }, { "title": "Del-1 in Psoriasis Induced the Expression of alphavbeta3 and alpha5beta1 in Endothelial Cells.", "journal": "Current molecular medicine", "date": "2022", "authors": "Niu X, Han Q, Li X, Li J, Liu Y, Li Y, Wu Y", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "34325631", "url": "https://glygen.org/publication/PubMed/34325631" } ] }, { "title": "Obesity and altered angiogenic-related gene expression in endometrial cancer.", "journal": "Gynecologic oncology", "date": "2021", "authors": "Cobb LP, Siamakpour-Reihani S, Zhang D, Qin X, Owzar K, Zhou C, Conrads TP, Maxwell GL, Darcy KM, Bateman NW, Litzi T, Bae-Jump V, Secord AA", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "34538531", "url": "https://glygen.org/publication/PubMed/34538531" } ] }, { "title": "Truncation of the TPR domain of OGT alters substrate and glycosite selection.", "journal": "Analytical and bioanalytical chemistry", "date": "2021", "authors": "Ramirez DH, Yang B, D'Souza AK, Shen D, Woo CM", "evidence": [ { "database": "O-GlcNAc Database", "id": "O43854", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O43854" } ], "reference": [ { "type": "PubMed", "id": "34725712", "url": "https://glygen.org/publication/PubMed/34725712" } ] }, { "title": "Del1 Is a Growth Factor for Skeletal Progenitor Cells in the Fracture Callus.", "journal": "Biomolecules", "date": "2023-08-03", "authors": "Sun Yuxi, Boyko Tatiana, Marecic Owen, Struck Danielle, Mann Randall K, Andrew Tom W, Lopez Michael, Tong Xinming, Goodman Stuart B, Yang Fan, Longaker Michael T, Chan Charles K F, Yang George P", "evidence": [ { "database": "RefSeq", "id": "NP_001265571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265571" } ], "reference": [ { "type": "PubMed", "id": "37627279", "url": "https://glygen.org/publication/PubMed/37627279" } ] }, { "title": "Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.", "journal": "Genes Dev.", "date": "1998", "authors": "Hidai C, Zupancic T, Penta K, Mikhail A, Kawana M, Quertermous EE, Aoka Y, Fukagawa M, Matsui Y, Platika D, Auerbach R, Hogan BL, Snodgrass R, Quertermous T", "evidence": [ { "database": "UniProtKB", "id": "O43854", "url": "https://www.uniprot.org/uniprot/O43854" } ], "reference": [ { "type": "PubMed", "id": "9420328", "url": 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