{ "uniprot_canonical_ac": "O15530-1", "uniprot_ac": "O15530", "uniprot_id": "PDPK1_HUMAN", "mass": { "chemical_mass": 63152.0, "monoisotopic_mass": 63152.0 }, "refseq": { "ac": "NP_001248745", "name": "3-phosphoinositide-dependent protein kinase 1 isoform 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745" }, "gene_names": [ { "name": "PDPK1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O15530", "id": "O15530" }, { "name": "PDK1; PDPK2; PDPK2P; PRO0461", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745", "id": "NP_001248745" }, { "name": "PDK1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O15530", "id": "O15530" }, { "name": "PDPK1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745", "id": "NP_001248745" } ], "protein_names": [ { "name": "3-phosphoinositide-dependent protein kinase 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O15530" }, { "name": "2.7.11.1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O15530" }, { "name": "3-phosphoinositide-dependent protein kinase 1 isoform 3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745", "id": "NP_001248745" }, { "name": "PkB kinase like gene 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; Putative 3-phosphoinositide-dependent protein kinase 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745", "id": "NP_001248745" }, { "name": "hPDK1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O15530" } ], "function": [ { "annotation": "A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001248745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745" }, { "database": "PubMed", "id": "35061720", "url": "https://glygen.org/publication/PubMed/35061720" } ] }, { "annotation": "Cooperative activation of PDK1 and AKT by MAPK4 enhances cancer growth and resistance to therapy. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001248745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745" }, { "database": "PubMed", "id": "37531320", "url": "https://glygen.org/publication/PubMed/37531320" } ] }, { "annotation": "Hsa_circ_0000081 promotes the function of gastric cancer through sponging hsa-miR-423-5p to influence 3-phosphoinositide-dependent kinase 1 expression.", "evidence": [ { "database": "RefSeq", "id": "NP_001248745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745" }, { "database": "PubMed", "id": "35302432", "url": "https://glygen.org/publication/PubMed/35302432" } ] }, { "annotation": "Hsa_circ_0000851 promotes PDK1/p-AKT-mediated cell proliferation and migration by regulating miR-1183 in triple-negative breast cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_001248745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745" }, { "database": "PubMed", "id": "36241055", "url": "https://glygen.org/publication/PubMed/36241055" } ] }, { "annotation": "SDC2 Stabilization by USP14 Promotes Gastric Cancer Progression through Co-option of PDK1. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001248745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001248745" }, { "database": "PubMed", "id": "37496999", "url": "https://glygen.org/publication/PubMed/37496999" } ] }, { "annotation": "Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, phosphorylating SMAD2, SMAD3, SMAD4 and SMAD7, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta. Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses. Provides negative feedback inhibition to toll-like receptor-mediated NF-kappa-B activation in macrophages. Isoform 3 is catalytically inactive.", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530#function" }, { "database": "PubMed", "id": "9707564", "url": "https://glygen.org/publication/PubMed/9707564" }, { "database": "PubMed", "id": "9445476", "url": "https://glygen.org/publication/PubMed/9445476" }, { "database": "PubMed", "id": "17371830", "url": "https://glygen.org/publication/PubMed/17371830" }, { "database": "PubMed", "id": "18835241", "url": "https://glygen.org/publication/PubMed/18835241" }, { "database": "PubMed", "id": "10480933", "url": "https://glygen.org/publication/PubMed/10480933" }, { "database": "PubMed", "id": "14585963", "url": "https://glygen.org/publication/PubMed/14585963" }, { "database": "PubMed", "id": "14604990", "url": "https://glygen.org/publication/PubMed/14604990" }, { "database": "PubMed", "id": "10995762", "url": "https://glygen.org/publication/PubMed/10995762" }, { "database": "PubMed", "id": "16251192", "url": "https://glygen.org/publication/PubMed/16251192" }, { "database": "PubMed", "id": "10226025", "url": "https://glygen.org/publication/PubMed/10226025" }, { "database": "PubMed", "id": "17327236", "url": "https://glygen.org/publication/PubMed/17327236" }, { "database": "PubMed", "id": "16207722", "url": "https://glygen.org/publication/PubMed/16207722" }, { "database": "PubMed", "id": "12167717", "url": "https://glygen.org/publication/PubMed/12167717" }, { "database": "PubMed", "id": "9094314", "url": "https://glygen.org/publication/PubMed/9094314" }, { "database": "PubMed", "id": "9768361", "url": "https://glygen.org/publication/PubMed/9768361" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs200076126", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs200076126" }, { "id": "rs200076126", "database": "ENSEMBL", "url": "https://www.ensembl.org/id/rs200076126" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 366, "end_pos": 366, "sequence_org": "S", "sequence_mut": "C", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->C).", "chr_id": "16", "chr_pos": "2586728", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S366", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1597062071", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1597062071" }, { "id": "rs1597062071", "database": "ENSEMBL", "url": "https://www.ensembl.org/id/rs1597062071" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 381, "end_pos": 381, "sequence_org": "S", "sequence_mut": "A", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->A).", "chr_id": "16", "chr_pos": "2586772", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S381", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs758443705", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs758443705" }, { "id": "rs758443705", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs758443705" }, { "id": "rs758443705", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs758443705" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 381, "end_pos": 381, "sequence_org": "S", "sequence_mut": "L", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->L).", "chr_id": "16", "chr_pos": "2586773", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S381", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "O15530", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O15530" }, { "id": "rs779064858", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs779064858" }, { "id": "rs779064858", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs779064858" }, { "id": "rs779064858", "database": "NCI-TCGA", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs779064858" }, { "id": "rs779064858", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs779064858#frequency_tab" }, { "id": "rs779064858", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs779064858" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 390, "end_pos": 390, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "S", "sequence_mut": "L", "comment": "Somatic mutation passed 1 out of 6 filters: o-glyco-site-loss (S->L).", "chr_id": "16", "chr_pos": "2586719", "ref_nt": "C", "alt_nt": "T", "minor_allelic_frequency": "", "site_lbl": "S390", "disease": [ { "disease_id": "DOID:363", "recommended_name": { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine cancer", "description": "A female reproductive organ cancer that is located_in the uterus." }, "synonyms": [ { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "CA - cancer of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "Tumour of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterus neoplasm", "description": "" } ] } ], "keywords": [ "biomuta", "somatic", "cancer", "disease", "ebi", "germline" ] }, { "evidence": [ { "id": "rs1361007557", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1361007557" }, { "id": "rs1361007557", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1361007557" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 392, "end_pos": 392, "sequence_org": "S", "sequence_mut": "Y", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->Y).", "chr_id": "16", "chr_pos": "2586725", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S392", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs547797391", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs547797391" }, { "id": "rs547797391", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs547797391" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 394, "end_pos": 394, "sequence_org": "S", "sequence_mut": "L", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->L).", "chr_id": "16", "chr_pos": "2586812", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S394", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1272187031", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1272187031" }, { "id": "rs1272187031", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1272187031#frequency_tab" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 394, "end_pos": 394, "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->P).", "chr_id": "16", "chr_pos": "2586730", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S394", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs547797391", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs547797391" }, { "id": "rs547797391", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs547797391" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 394, "end_pos": 394, "sequence_org": "S", "sequence_mut": "W", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->W).", "chr_id": "16", "chr_pos": "2586812", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S394", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs765088097", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs765088097" }, { "id": "rs765088097", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs765088097" }, { "id": "rs765088097", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs765088097#frequency_tab" }, { "id": "rs765088097", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs765088097" }, { "id": "rs780305703", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs780305703" }, { "id": "rs780305703", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs780305703" }, { "id": "rs780305703", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs780305703" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 396, "end_pos": 396, "sequence_org": "S", "sequence_mut": "C", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->C).", "chr_id": "16", "chr_pos": "2586818", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S396", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1597061858", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1597061858" }, { "id": "rs1597061858", "database": "ENSEMBL", "url": "https://www.ensembl.org/id/rs1597061858" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 396, "end_pos": 396, "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->P).", "chr_id": "16", "chr_pos": "2586736", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S396", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "O15530", "database": "BioMuta", "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/O15530" } ], "glycoeffect": [ "o-glyco-site-loss" ], "start_pos": 400, "end_pos": 400, "subjects_tested": "0", "subjects_positive": "0", "frequency": "0.0", "sequence_org": "S", "sequence_mut": "Y", "comment": "Somatic mutation passed 1 out of 6 filters: o-glyco-site-loss (S->Y).", "chr_id": "16", "chr_pos": "2586749", "ref_nt": "C", "alt_nt": "A", "minor_allelic_frequency": "", "site_lbl": "S400", "disease": [ { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "A thoracic cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ], "keywords": [ "biomuta", "somatic", "cancer", "disease" ] }, { "evidence": [ { "id": "rs76887737", "database": "dbSNP", "url": 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"https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", 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"" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, 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"https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", 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"resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "No", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "O15530", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O15530" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", 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"https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": 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results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": 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"https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the 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"" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine 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{ "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast 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"description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "O15530", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O15530" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid neoplasm", "description": "" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Kidney cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:263", "evidence": [ { "database": "BioXpress", "id": "O15530", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O15530" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BPR5", "url": "https://www.uniprot.org/uniprot/H3BPR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BPR5-1", "url": "https://www.uniprot.org/uniprot/H3BPR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BPW1", "url": "https://www.uniprot.org/uniprot/H3BPW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BPW1-1", "url": "https://www.uniprot.org/uniprot/H3BPW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BQ10", "url": "https://www.uniprot.org/uniprot/H3BQ10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BQ10-1", "url": "https://www.uniprot.org/uniprot/H3BQ10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BQA3", "url": "https://www.uniprot.org/uniprot/H3BQA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H3BQA3-1", "url": "https://www.uniprot.org/uniprot/H3BQA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O15530-1", "url": "https://www.uniprot.org/uniprot/O15530-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O15530-2", "url": "https://www.uniprot.org/uniprot/O15530-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O15530-3", "url": "https://www.uniprot.org/uniprot/O15530-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O15530-4", "url": "https://www.uniprot.org/uniprot/O15530-4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O15530-5", "url": "https://www.uniprot.org/uniprot/O15530-5", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ", "length": 556, "header": "sp|O15530-1|PDPK1_HUMAN Isoform 1 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "isoforms": [ { "isoform_ac": "E9PER6-1", "url": "", "sequence": { "sequence": "MVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ", "length": 529, "header": "tr|E9PER6-1|PDPK1_HUMAN Computationally mapped isoform of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2597764, "end_pos": 2557760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000389224.7", "url": "https://www.ensembl.org/id/ENST00000389224.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000373876.3", "url": "https://www.ensembl.org/id/ENSP00000373876.3" } ] } }, { "isoform_ac": "H3BNV5-1", "url": "", "sequence": { "sequence": "MARTTSQLRNRPGLPPGTGSLAPPPAREAEGASSC", "length": 35, "header": "tr|H3BNV5-1|H3BNV5_HUMAN Computationally mapped isoform of 3-phosphoinositide dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=4 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2538582, "end_pos": 2538113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000474706.6", "url": "https://www.ensembl.org/id/ENST00000474706.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000455025.1", "url": "https://www.ensembl.org/id/ENSP00000455025.1" } ] } }, { "isoform_ac": "H3BPR5-1", "url": "", "sequence": { "sequence": "XHHSELETSILYFRRSLSWNMTFQKNSSLRQETSWRNFWF", "length": 40, "header": "tr|H3BPR5-1|H3BPR5_HUMAN Computationally mapped isoform of 3-phosphoinositide dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=4 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2583417, "end_pos": 2581347, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000478708.2", "url": "https://www.ensembl.org/id/ENST00000478708.2" }, { "database": "Ensembl Peptide", "id": "ENSP00000455438.1", "url": "https://www.ensembl.org/id/ENSP00000455438.1" } ] } }, { "isoform_ac": "H3BPW1-1", "url": "", "sequence": { "sequence": "MKICTSRSQILEQQKSYPQRANKPGPTHSWEQRSTFLQSCSRRSPPVRDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE", "length": 88, "header": "tr|H3BPW1-1|H3BPW1_HUMAN Computationally mapped isoform of 3-phosphoinositide dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=4 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2581661, "end_pos": 2566385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000566659.1", "url": "https://www.ensembl.org/id/ENST00000566659.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000455492.1", "url": "https://www.ensembl.org/id/ENSP00000455492.1" } ] } }, { "isoform_ac": "H3BQ10-1", "url": "", "sequence": { "sequence": "MVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGS", "length": 149, "header": "tr|H3BQ10-1|H3BQ10_HUMAN Computationally mapped isoform of 3-phosphoinositide dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2565614, "end_pos": 2557760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000461815.1", "url": "https://www.ensembl.org/id/ENST00000461815.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000455551.1", "url": "https://www.ensembl.org/id/ENSP00000455551.1" } ] } }, { "isoform_ac": "H3BQA3-1", "url": "", "sequence": { "sequence": "MARTTSQLILDDSGRENSPFTARPRGIWVLLLPVAVLSVVGSPWEAECAGSPRGK", "length": 55, "header": "tr|H3BQA3-1|PDPK1_HUMAN Computationally mapped isoform of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2538759, "end_pos": 2538113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000492021.6", "url": "https://www.ensembl.org/id/ENST00000492021.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000455684.1", "url": "https://www.ensembl.org/id/ENSP00000455684.1" } ] } }, { "isoform_ac": "O15530-1", "url": "", "sequence": { "sequence": "MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ", "length": 556, "header": "sp|O15530-1|PDPK1_HUMAN Isoform 1 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2597764, "end_pos": 2538113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000342085.9", "url": "https://www.ensembl.org/id/ENST00000342085.9" }, { "database": "Ensembl Peptide", "id": "ENSP00000344220.4", "url": "https://www.ensembl.org/id/ENSP00000344220.4" } ] } }, { "isoform_ac": "O15530-2", "url": "", "sequence": { "sequence": "MDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ", "length": 506, "header": "sp|O15530-2|PDPK1_HUMAN Isoform 2 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": {} }, { "isoform_ac": "O15530-3", "url": "", "sequence": { "sequence": "MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQADLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ", "length": 530, "header": "sp|O15530-3|PDPK1_HUMAN Isoform 3 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": {} }, { "isoform_ac": "O15530-4", "url": "", "sequence": { "sequence": "MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYATRANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ", "length": 429, "header": "sp|O15530-4|PDPK1_HUMAN Isoform 4 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2597764, "end_pos": 2538113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000268673.11", "url": "https://www.ensembl.org/id/ENST00000268673.11" }, { "database": "Ensembl Peptide", "id": "ENSP00000268673.7", "url": "https://www.ensembl.org/id/ENSP00000268673.7" } ] } }, { "isoform_ac": "O15530-5", "url": "", "sequence": { "sequence": "MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPCLTGRII", "length": 454, "header": "sp|O15530-5|PDPK1_HUMAN Isoform 5 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1 CANONICAL=O15530-1" }, "locus": { "chromosome": "16", "start_pos": 2597669, "end_pos": 2538113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000441549.7", "url": "https://www.ensembl.org/id/ENST00000441549.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000395357.3", "url": "https://www.ensembl.org/id/ENSP00000395357.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 105, "start_aa": "Ser", "end_pos": 105, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser105", "evidence": [ { "id": "O15530", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O15530" }, { "id": "36580660", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36580660" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 222, "start_aa": "Thr", "end_pos": 222, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr222", "evidence": [ { "id": "O15530", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O15530" }, { "id": "36580660", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36580660" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 22, "start_aa": "Ser", "end_pos": 22, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser22", "evidence": [ { "id": "O15530", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O15530" }, { "id": "36580660", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36580660" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 354, "start_aa": "Thr", "end_pos": 354, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr354", "evidence": [ { "id": "O15530", "database": "O-GlcNAc 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"url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "negative regulation of cardiac muscle cell apoptotic process", "id": "GO:0010667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010667", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "type B pancreatic cell development", "id": "GO:0003323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003323", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "hyperosmotic response", "id": "GO:0006972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006972", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Phosphorylation on Ser-241 in the activation loop is required for full activity. PDPK1 itself can autophosphorylate Ser-241, leading to its own activation. Autophosphorylation is inhibited by the apoptotic C-terminus cleavage product of PKN2 (By similarity). Tyr-9 phosphorylation is critical for stabilization of both PDPK1 and the PDPK1/SRC complex via HSP90-mediated protection of PDPK1 degradation. Angiotensin II stimulates the tyrosine phosphorylation of PDPK1 in vascular smooth muscle in a calcium- and SRC-dependent manner. Phosphorylated on Tyr-9, Tyr-373 and Tyr-376 by INSR in response to insulin. Palmitate negatively regulates autophosphorylation at Ser-241 and palmitate-induced phosphorylation at Ser-529 and Ser-501 by PKC/PRKCQ negatively regulates its ability to phosphorylate PKB/AKT1. Phosphorylation at Thr-354 by MELK partially inhibits kinase activity, the inhibition is cooperatively enhanced by phosphorylation at Ser-394 and Ser-398 by MAP3K5.", "evidence": [ { "database": "UniProtKB", "id": "O15530", "url": "https://www.uniprot.org/uniprot/O15530" }, { "database": "PubMed", "id": "10455013", "url": "https://glygen.org/publication/PubMed/10455013" }, { "database": "PubMed", "id": "16780920", "url": "https://glygen.org/publication/PubMed/16780920" }, { "database": "PubMed", "id": "22544756", "url": "https://glygen.org/publication/PubMed/22544756" }, { "database": "PubMed", "id": "15743829", "url": "https://glygen.org/publication/PubMed/15743829" }, { "database": "PubMed", "id": "14585963", "url": "https://glygen.org/publication/PubMed/14585963" }, { "database": "PubMed", "id": "16314505", "url": "https://glygen.org/publication/PubMed/16314505" }, { "database": "PubMed", "id": "11481331", "url": "https://glygen.org/publication/PubMed/11481331" } ] } ], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B2DD29-1", "D3ZML2-1", "O08875-1", "O35831-1", "D3ZHP7-1", "D4A280-1", "E9PTG8-1", "O35832-1", "O54748-1", "P57760-1", "Q62868-1", "D3ZBE5-1", "P59895-1", "O55099-1", "O88764-1", "P59241-1", "Q91XS8-1", "Q63644-1", "Q7TQP6-1", "Q9Z2P5-1", "P11345-1", "P11275-1", "F1LYY7-1", "Q9JIH7-1", "P14056-1", "P35426-1", "P51952-1", "P63086-1", "Q5U2X5-1", "Q5XIT0-1", "Q63117-1", "F1M7Y5-1", "P47196-1", "P47197-1", "P97874-1", "Q03114-1", "Q3MJK5-1", "Q09137-1", "Q4V8A3-1", "P54645-1", "Q63686-1", "P08413-1", "P0C1X8-1", "P19139-1", "D4A7V9-1", "Q63184-1", "Q63484-1", "Q9Z1Z1-1", "Q4KM34-1", "Q4KM47-1", "O08874-1", "O70444-1", "O88831-1", "P0C0R5-1", "P26794-1", "P46892-1", "Q66HE7-1", "Q6XUX2-1", "Q62915-1", "Q63185-1", "Q63470-1", 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"P38691-1", "P53104-1", "P53323-1", "P54199-1", "Q01389-1", "Q03656-1", "Q08217-1", "Q03306-1", "Q03533-1", "Q03785-1", "Q12003-1", "Q12100-1", "Q12196-1", "Q12236-1", "Q12469-1", "Q12505-1", "P43637-1", "P47042-1", "P50873-1", "Q03002-1", "Q06098-1", "Q08732-1", "Q12152-1", "Q12222-1", "Q12310-1", "Q54FH3-1", "Q54R98-1", "Q54RP7-1", "Q55FJ6-1", "Q55GG4-1", "Q54C38-1", "Q54DY0-1", "Q54E34-1", "Q54EM1-1", "Q54ER4-1", "Q54ET3-1", "Q54F40-1", "Q54FR9-1", "Q54G43-1", "Q54H05-1", "Q54HD2-1", "Q54IF2-1", "Q54IH8-1", "Q54IP4-1", "Q54JQ1-1", "Q54L00-1", "Q54L81-1", "Q54LH8-1", "Q54LU8-1", "Q54MH0-1", "Q54MV2-1", "Q54P26-1", "Q54PK8-1", "Q54PX0-1", "Q54QD5-1", "Q54R95-1", "Q54RB2-1", "Q54RJ4-1", "Q54RR9-1", "Q54RV3-1", "Q54RZ7-1", "Q54SC4-1", "Q54SK3-1", "Q54TA3-1", "Q54TH6-1", "Q54TN4-1", "Q54U31-1", "Q54U65-1", "Q54UA9-1", "Q54UZ1-1", "Q54V35-1", "Q54V83-1", "Q54VC0-1", "Q54VU4-1", "Q54VV7-1", "Q54WC0-1", "Q54WD7-1", "Q54WE5-1", "Q54WW7-1", "Q54XJ4-1", "Q54XX5-1", "Q54XY6-1", "Q54XZ5-1", "Q54Y06-1", "Q54Y55-1", "Q54Y90-1", "Q54YZ5-1", "Q54ZN3-1", "Q552C1-1", "Q552E9-1", "Q552Z2-1", "Q553E9-1", "Q556J6-1", "Q559A2-1", "Q559T8-1", "Q55A09-1", "Q55A55-1", "Q55BA0-1", "Q55CA6-1", "Q55CE0-1", "Q55CW2-1", "Q55CW3-1", "Q55DJ9-1", "Q55DK2-1", "Q55DU7-1", "Q55EI8-1", "Q55F45-1", "Q55FV4-1", "Q55FV5-1", "Q55GC2-1", "Q55GE6-1", "Q55GS4-1", "Q55GU0-1", "Q6XHA7-1", "Q75JN1-1", "Q76P07-1", "Q869L4-1", "Q869T7-1", "Q869X3-1", "Q86A12-1", "Q86HG9-1", "Q86HW6-1", "Q86I06-1", "Q8MYF1-1", "Q8SSV3-1", "Q9NGW9-1", "P0CD62-1", "P34100-1", "P34102-1", "P34103-1", "Q1ZXC8-1", "Q1ZXH2-1", "Q1ZXI5-1", "Q1ZXR2-1", "Q23915-1", "Q54HS0-1", "O61122-1", "O61125-1", "P28178-1", "P34099-1", "P34101-1", "P34112-1", "P34117-1", "P42525-1", "P54644-1", "P54685-1", "Q02720-1", "Q1ZXD6-1", "Q54B33-1", "Q54B48-1", "Q54BC9-1", "Q54BF0-1", "Q54C18-1", "Q54C71-1", "Q54D75-1", "Q54DC8-1", "Q54DF2-1", "Q54DK3-1", "Q54EG9-1", "Q54EY4-1", "Q54GY6-1", "Q54H45-1", "Q54H46-1", "Q54HC6-1", "Q54I36-1", "Q54IE8-1", "Q54JC7-1", "Q54JG7-1", "Q54LR6-1", "Q54M77-1", "Q54MY9-1", "Q54P47-1", "Q54PK9-1", "Q54Q69-1", "Q54QB1-1", "Q54QI2-1", "Q54QQ1-1", "Q54QV3-1", "Q54R82-1", "Q54RB7-1", "Q54S77-1", "Q54T05-1", "Q54TA1-1", "Q54TM7-1", "Q54TW2-1", "Q54UC0-1", "Q54UL8-1", "Q54VD8-1", "Q54VI1-1", "Q54W07-1", "Q54WJ0-1", "Q54WS5-1", "Q54WX4-1", "Q54XL6-1", "Q54XQ2-1", "Q54Y26-1", "Q54YF2-1", "Q550K8-1", "Q550L8-1", "Q551H4-1", "Q552C6-1", "Q556Q3-1", "Q556S2-1", "Q556Y4-1", "Q557G1-1", "Q558U1-1", "Q55BN8-1", "Q55CL6-1", "Q55CY9-1", "Q55CZ1-1", "Q55D99-1", "Q55DD4-1", "Q55DJ8-1", "Q55E58-1", "Q55EC7-1", "Q55FS2-1", "Q55FT4-1", "Q55GJ2-1", "Q55GV3-1", "Q5VJL3-1", "Q6B9X6-1", "Q6XHA5-1", "Q6XHB2-1", "Q75JK0-1", "Q76NV1-1", "Q869N2-1", "Q86AE1-1", "Q86AT8-1", "Q86C65-1", "Q86CS2-1", "Q86HN7-1", "Q86IX1-1", "Q8MVR1-1", "Q8SSS9-1", "Q8SSY6-1", "Q8T2I8-1", "Q95YH0-1", "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83098-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "A0A0B4KHX7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "M9PI41-1", "Q9VM90-1", "A1ZBL9-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P49762-1", "P54367-1", "P83099-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "Q9NIV1-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "P54360-1", "Q9VT57-1", "Q9VI13-1", "A1ZBC4-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "Q7PLI7-1", "X2JAG8-1", "O61661-1", "A4VCL2-2", "A0A0B4KHT3-1", "A0A4D6K823-1", "Q9VP22-1", "Q9VZI2-1", "Q9W1B0-1", "Q9V3I5-1", "A1ZBH7-1", "Q9W002-1", "Q9VRJ6-1", "Q8T9L5-1", "Q94533-1", "Q9VUQ9-1", "Q9VXE3-1", "Q9VGF9-1", "Q9VBU2-1", "Q9VR42-1", "Q9VW24-1", "A0A0B4KHC3-1", "Q9VL34-1", "Q9VTL5-1", "Q95TN8-1", "Q9VCV0-1", "Q8MSQ4-1", "Q9VE06-1", "Q9VJ30-1", "Q9VXN5-1", "M9PGC5-1", "Q9VN23-1", "M9NGC6-1", "O61444-1", "O62602-1", "Q9VUV4-1", "Q9VMY8-1", "Q9VD82-1", "A0A6M3Q7C8-1", "Q9W3N8-1", "Q95SH0-1", "Q9VJC2-1", "Q9VI84-1", "Q9VEN3-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-HSA-109701", "name": "PDPK1 binds PIP3", "equation": "", "summary": "PIP3 generated by PI3K recruits phosphatidylinositide-dependent protein kinase 1 (PDPK1 i.e. PDK1) to the membrane, through its PH (pleckstrin-homology) domain. PDPK1 binds PIP3 with high affinity, and also shows low affinity for PIP2 (Currie et al. 1999; Anderson et al, 1998).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-109701", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-109701" } ] }, { "id": "R-HSA-109702", "name": "PDPK1 phosphorylates AKT2", "equation": "", "summary": "Two specific sites in AKT2, one in the kinase domain (Thr-309) and the other in the C-terminal regulatory region (Ser-474), need to be phosphorylated for its full activation.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P31751-1" ], "evidence": [ { "id": "R-HSA-109702", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-109702" } ] }, { "id": "R-HSA-198270", "name": "PDPK1 phosphorylates AKT at T308", "equation": "", "summary": "Once AKT is localized at the plasma membrane, it is phosphorylated at two critical residues for its full activation. These residues are a threonine (T308 in AKT1) in the activation loop within the catalytic domain, and a serine (S473 in AKT1), in a hydrophobic motif (HM) within the carboxy terminal, non-catalytic region. PDPK1 (PDK1) is the activation loop kinase; this kinase can also directly phosphorylate p70S6K. The HM kinase, previously termed PDK2, has been identified as the mammalian TOR (Target Of Rapamycin; Sarbassov et al., 2005) but several other kinases are also able to phosphorylate AKT at S473. Phosphorylation of AKT at S473 by TORC2 complex is a prerequisite for PDPK1-mediated phosphorylation of AKT threonine T308 (Scheid et al. 2002, Sarabassov et al. 2005).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P31749-1", "P31751-1", "Q9Y243-1" ], "evidence": [ { "id": "R-HSA-198270", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-198270" } ] }, { "id": "R-HSA-202164", "name": "Translocation of PDK1 to Plasma membrane", "equation": "", "summary": "PI3K activation results in recruitment of the serine/threonine kinase PDK1, (3-phosphoinositide-dependent kinase 1) to the plasma membrane where PDK1 subsequently phosphorylates and activates AKT. PDK1 with its PH domain binds to either PIP3 or PIP2 and is translocated to the plasma membrane. PDK1 seems to exist in an active, phosphorylated configuration under basal conditions (Vanhaesebroeck & Alessi 2000).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-202164", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202164" } ] }, { "id": "R-HSA-202222", "name": "Phosphorylation of PKC theta", "equation": "", "summary": "Raft localized PKC theta is further phosphorylated and activated by PDK1. The threonine residue (T538) in the kinase domain is the potential target of PDK1. Phosphorylation of this site is critical for the PKC theta kinase activity, and its ability to activate NF-kB pathway. PKC theta is later trans-autophopshorylated on putative phosphorylation sites (S676, S695) for the fine-tuning of its kinase activity.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q04759-1" ], "evidence": [ { "id": "R-HSA-202222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202222" } ] }, { "id": "R-HSA-202394", "name": "Translocation of CARMA1 to Plasma membrane", "equation": "", "summary": "CARMA1 and Bcl10 are the possible link between PKC theta and IKK activation. PDK1 is also required for PKC theta mediated activation of IKK. CARMA1 has a N-terminal CARD motif, a coiled coiled region, a linker region, and a MAGUK-typical PDZ, SH3 and a GUK domains. The linker region is proposed to contain a hinge region and a CARD binding domain. CARMA1 exists in an inactive conformation in which the linker region binds to and blocks the accessibility of the CARD motif. CARMA1 is recruited to the plasma membrane by binding to the 'PxxP' motif of membrane bound PDK1 with its SH3 domain.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-202394", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202394" } ] }, { "id": "R-HSA-202437", "name": "Phosphorylation of CARMA1", "equation": "", "summary": "Antigen receptor triggered PKC theta dependent linker phosphorylation of S559 residue is required to release this inhibition and expose the CARD motif for downstream Bcl10 recruitment (Sommer et al. 2005). PDK1 and maybe other unknown adapter proteins bring PKC theta and CARMA1 into close proximity, facilitating PKC theta mediated CARMA1 phosphorylation and consequent activation.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q04759-1" ], "evidence": [ { "id": "R-HSA-202437", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202437" } ] }, { "id": "R-HSA-202443", "name": "Oligomerization of CARMA1", "equation": "", "summary": "After the phosphorylation and activation CARMA1 undergoes oligomerization, likely through its CC domain. CARMA1 is thought to oligomerize first as a trimer which triggers downstream oligomerization cascade that is ultimately necessary for the subsequent activation of the IKK complex.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-202443", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202443" } ] }, { "id": "R-HSA-202453", "name": "Auto-ubiquitination of TRAF6", "equation": "", "summary": "TRAF6 possesses ubiquitin ligase activity and undergoes K-63-linked auto-ubiquitination after its oligomerization. In the first step, ubiquitin is activated by an E1 ubiquitin activating enzyme. The activated ubiquitin is transferred to a E2 conjugating enzyme (a heterodimer of proteins Ubc13 and Uev1A) forming the E2-Ub thioester. Finally, in the presence of ubiquitin-protein ligase E3 (TRAF6, a RING-domain E3), ubiquitin is attached to the target protein (TRAF6 on residue Lysine 124) through an isopeptide bond between the C-terminus of ubiquitin and the epsilon-amino group of a lysine residue in the target protein. In contrast to K-48-linked ubiquitination that leads to the proteosomal degradation of the target protein, K-63-linked polyubiquitin chains act as a scaffold to assemble protein kinase complexes and mediate their activation through proteosome-independent mechanisms. This K63 polyubiquitinated TRAF6 activates the TAK1 kinase complex.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-HSA-450152" ], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q9Y4K3-1", "Q9UDY8-1", "P61088-1" ], "evidence": [ { "id": "R-HSA-202453", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202453" } ] }, { "id": "R-HSA-202459", "name": "Phosphorylation of Bcl10", "equation": "", "summary": "Upon interaction with CARMA1, Bcl10 undergoes phosphorylation and oligomerization. The oligomerized Bcl10 acts as a adaptor for the incoming MALT1 and TRAF6. Phosphorylation events of Bcl10 can both positively and negatively regulate the NF-kB pathway. Phosphorylation of Bcl10 that depends on the Ser/Thr kinase RIP2 and correlated with the physical association of Bcl10 with RIP2 has a activation effect on the NF-kB pathway. The target sites of RIP2-mediated phosphorylation has not yet been identified.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "O43353-1" ], "evidence": [ { "id": "R-HSA-202459", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202459" } ] }, { "id": "R-HSA-202466", "name": "Interaction of Bcl10 to CARMA1", "equation": "", "summary": "Bcl10 is recruited to activated, oligomeric CARMA1 through a CARD-CARD interaction. Bcl10 is characterized by an N-terminal CARD motif and a C-terminal extension of ~130 amino acids rich in serine and threonine residues that serve as targets for multiple phosphorylation events.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-202466", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202466" } ] }, { "id": "R-HSA-202472", "name": "Translocation of TRAF6 to CBM complex", "equation": "", "summary": "TRAF6, which plays central role in innate immune responses, is implicated as proximal downstream effector of MALT1. TRAF6 is a member of the TRAF proteins. It contains an N-term RING domain, followed by several Zn finger domains and C-term MATH domain. The MALT1 oligomers bind to TRAF6, induce TRAF6 oligomerization and thereby activate the ubiquitin ligase activity of TRAF6 to polyubiquitinate itself and NEMO.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q9Y4K3-1", "Q9UDY8-1" ], "evidence": [ { "id": "R-HSA-202472", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202472" } ] }, { "id": "R-HSA-202478", "name": "Interaction and oligomerization of MALT1 to Bcl10", "equation": "", "summary": "Oligomerized Bcl10 facilitates the association with MALT1 to form the CBM signalosome. MALT1 possesses one death domain (DD) and 2 immunoglobulin-like domains (Ig-like) in its N-terminal region and a caspase like domain (CLD) in its C-terminal region. The region between amino acids 107 and 119 of Bcl10 bind to the two Ig-like domains of MALT1. After binding to CARMA1 and Bcl10 complex, MALT1 also undergoes oligomerization. Only the oligomerized forms of Bcl10 and MALT1 are capable of activating IKK.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q9UDY8-1" ], "evidence": [ { "id": "R-HSA-202478", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202478" } ] }, { "id": "R-HSA-202489", "name": "Oligomerization of Bcl10", "equation": "", "summary": "Association with RIP2 and its phosphorylation allows subsequent trimerization of Bcl10.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-202489", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202489" } ] }, { "id": "R-HSA-202500", "name": "Activation of IKK complex", "equation": "", "summary": "The IkB kinase (IKK) complex serves as the master regulator for the activation of NF-kB by various stimuli. It contains two catalytic subunits, IKK alpha and IKK beta, and a regulatory subunit, IKKgamma/NEMO. The activation of IKK complex is dependent on the phosphorylation of IKK alpha/beta at its activation loop and the K63-linked ubiquitination of NEMO. This basic trimolecular complex is referred to as the IKK complex.
IKK subunits have a N-term kinase domain a leucine zipper (LZ) motifs, a helix-loop-helix (HLH) and a C-ter NEMO binding domain (NBD). IKK catalytic subunits are dimerized through their LZ motifs. IKK beta is the major IKK catalytic subunit for NF-kB activation. Activated TAK1 phosphorylate IKK beta on serine residues (S177 and S181) in the activation loop and thus activate the IKK kinase activity, leading to the IkB alpha phosphorylation and NF-kB activation.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O43318-1", "O15530-1", "O15111-1", "Q9Y4K3-1", "O14920-1", "Q9UDY8-1" ], "evidence": [ { "id": "R-HSA-202500", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202500" } ] }, { "id": "R-HSA-202510", "name": "Activation of TAK1-TAB2 complex", "equation": "", "summary": "Ubiquitinated TRAF6 recruits TAB2 and activates the TAB2-associated TAK1 kianse by promoting the autophosphorylation of TAK1. TAB2 contains an N-term pseudophosphatase domain, which is indispensable for TAK1 activation, and a C-term domain that binds to and activates TAK1. The activation of TAK1/TAB2 complex requires a ubiquitination reaction catalysed by E1, Ubc13/Uev1A (E2) and TRAF6 (E3). TAK1 undergoes autophosphorylation on residues T184 and T187 and gets activated. Activated TAK1 then phosphorylates and activates IKK beta.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O43318-1", "O15530-1", "Q9Y4K3-1", "Q9UDY8-1" ], "evidence": [ { "id": "R-HSA-202510", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202510" } ] }, { "id": "R-HSA-202534", "name": "Ubiquitination of NEMO by TRAF6", "equation": "", "summary": "During the phosphorylation of the IKK beta, the regulatory subunit NEMO undergoes K-63-linked polyubiquitination. Ubiquitinated TRAF6 trimer, acts as a E3 ligase and induces this ubiquitination. The ubiquitin target sites in NEMO are not yet clearly identified. Studies of different NF-kB signaling pathways revealed several potential ubiquitination sites on NEMO (e.g., K285, K277, K309 and K399) (Fuminori et al. 2009).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-HSA-202562" ], "enzyme_list": [ "O15530-1", "O15111-1", "Q9Y4K3-1", "O14920-1", "Q9UDY8-1", "P61088-1" ], "evidence": [ { "id": "R-HSA-202534", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202534" } ] }, { "id": "R-HSA-2219524", "name": "PDPK1 binds PIP2", "equation": "", "summary": "PDPK1 (PDK1) possesses low affinity for PIP2, so small amounts of PDPK1 are always present at the membrane, in the absence of PI3K activity (Currie et al. 1999).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-2219524", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2219524" } ] }, { "id": "R-HSA-2243937", "name": "PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1", "equation": "", "summary": "A portion of PDPK1 (PDK1) is anchored to the plasma membrane in the absence of PI3K activity through PIP2 binding (Currie et al. 1999). This PIP2-bound PDPK1 is able to bind and phosphorylate PIP2-bound AKT E17K mutants (Carpten et al. 2007, Landgraf et al. 2008) phosphorylated on serine residue S473.", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P31749-1" ], "evidence": [ { "id": "R-HSA-2243937", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2243937" } ] }, { "id": "R-HSA-2243942", "name": "PDPK1 phosphorylates AKT1 E17K mutant", "equation": "", "summary": "PIP2-bound AKT1 E17K mutant is constitutively phosphorylated on threonine residue T308 (Carpten et al. 2007, Landgraf et al. 2008), presumably by PIP2-bound PDPK1 (Currie et al. 1999).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-HSA-2243935" ], "enzyme_list": [ "O15530-1", "P31749-1" ], "evidence": [ { "id": "R-HSA-2243942", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2243942" } ] }, { "id": "R-HSA-2316429", "name": "PIP3 recruits PDPK1 to the membrane", "equation": "", "summary": "PIP3 generated by PI3K recruits phosphatidylinositide-dependent protein kinase 1 (PDPK1 i.e. PDK1) to the membrane, through its PH (pleckstrin-homology) domain. PDPK1 binds PIP3 with high affinity, and also shows low affinity for PIP2 (Currie et al. 1999).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-2316429", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2316429" } ] }, { "id": "R-HSA-2317314", "name": "AKT binds PDPK1", "equation": "", "summary": "Once phosphorylated on serine residue S473, AKT bound to PIP3 forms a complex with PIP3-bound PDPK1 i.e. PDK1 (Scheid et al. 2002, Sarabassov et al. 2005)", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P31749-1", "P31751-1", "Q9Y243-1" ], "evidence": [ { "id": "R-HSA-2317314", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2317314" } ] }, { "id": "R-HSA-432110", "name": "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding", "equation": "", "summary": "The binding of SHC to integrin alpha IIb beta 3 is blocked by phosphorylation of beta 3 at Thr-779, or by substitution of this residue for Asp. PDK1 and Akt1/PKB-alpha both specifically target Thr-779 in in vitro assays.", "cellular_location": "plasma membrane", "input_participant_list": [ "R-HSA-114514" ], "output_participant_list": [ "R-HSA-432105" ], "enzyme_list": [ "O15530-1", "P31749-1" ], "evidence": [ { "id": "R-HSA-432110", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-432110" } ] }, { "id": "R-HSA-437192", "name": "PDPK1 binds PRKCZ", "equation": "", "summary": "3-phosphoinositide dependent protein kinase-1 (PDPK1, also known as PDK1) and Protein kinase C zeta type (PRKCZ, also known as PKC zeta) are associated in fibroblasts.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q05513-1" ], "evidence": [ { "id": "R-HSA-437192", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-437192" } ] }, { "id": "R-HSA-437195", "name": "PDPK1 activates PRKCZ", "equation": "", "summary": "3-phosphoinositide dependent protein kinase-1 (Pdpk1, also known as Pdk1 and PKB kinase because of its activity at Protein kinase B) phosphorylates T410 of protein kinase C zeta type (Prkcz, also known as PKC zeta), leading to activation. The motif surrounding T410 is highly conserved in other PKC family members suggesting that Pdpk1 might activate other PKCs.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q05513-1" ], "evidence": [ { "id": "R-HSA-437195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-437195" } ] }, { "id": "R-HSA-442739", "name": "PDPK1 phosphorylates RSKs", "equation": "", "summary": "PDPK1 (PDK1) activates ribosomal S6 kinases (RSKs) by phosphorylating a conserved serine residue S221 (in RPS6KA1). The binding site for PDPK1 on RSKs is available after RSK phosphorylation by MAPKs/ERKs. PDPK1 is present in the activated form at the plasma membrane where the phosphorylation occurs (Jensen et al. 1999).", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q15349-1", "P51812-1", "O15530-1", "Q15418-1", "Q9UK32-1" ], "evidence": [ { "id": "R-HSA-442739", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-442739" } ] }, { "id": "R-HSA-5218821", "name": "PDK1 phosphorylates PKC", "equation": "", "summary": "Protein kinase C (PKC) activation enhances angiogenesis by participating in the intracellular signaling of vascular endothelial growth factor (VEGF) in endothelial cells. VEGF can activate several PKC isoforms including alpha, beta, delta and zeta isoforms. Their activation is preceded by the activation of PLC gamma (Suzuma et al. 2002, Xia et al. 1996, Takahashi et al. 1999, Wellner et al. 1999). Before Protein kinase C (PKC) is competent to respond to second messengers it must first be phosphorylated at three conserved positions: the activation loop and two positions at the carboxyl terminus of the protein (Dutil et al. 1998). The phosphorylation of the activation loop appears to occur first and is mediated by phosphoinositide dependent protein kinases (PDKs). PDK1 phosphorylates PKCs at a critical Thr (T) residue in the activation loop, a requirement for PKC to gain catalytic competency (Toker 2003).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05655-1", "O15530-1", "Q05513-1", "P17252-1", "P05771-1" ], "evidence": [ { "id": "R-HSA-5218821", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5218821" } ] }, { "id": "R-HSA-5623632", "name": "RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3", "equation": "", "summary": "Binding of PKN1, PKN2 or PKN3 to any of the RHO GTP-ases RHOA, RHOB, RHOC or RAC1 enables PKN1, PKN2 and PKN3 to interact with PIP3-activated kinase PDPK1, through the formation of ternary complexes (Flynn et al. 2000, Torbett et al. 2003).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P63000-1", "Q16512-1", "P61586-1", "Q6P5Z2-1", "Q16513-1" ], "evidence": [ { "id": "R-HSA-5623632", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5623632" } ] }, { "id": "R-HSA-5623667", "name": "PDPK1 phosphorylates PKN1,2,3", "equation": "", "summary": "PDPK1 (PDK1) phosphorylates PKN1, PKN2 and likely PKN3 on a highly conserved threonine residue (T774 of PKN1, T816 of PKN2, T718 of PKN3) in the kinase activation loop. Although phosphorylation of PKN1, PKN2 and PKN3 at other sites may be needed for them to achieve the full catalytic activity, PDPK1-mediated phosphorylation of the activation loop is a necessary step in PKN1, PKN2 and likely PKN3 activation. This reaction happens while the PKN protein is complexed with a RHO GTPase and PIP3-bound PDPK1 (Flynn et al. 2000, Torbett et al. 2003, Dettori et al. 2009).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P63000-1", "Q16512-1", "P61586-1", "Q6P5Z2-1", "Q16513-1" ], "evidence": [ { "id": "R-HSA-5623667", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-5623667" } ] }, { "id": "R-HSA-6795473", "name": "PDPK1 phosphorylates SGK1", "equation": "", "summary": "PDPK1 (PDK1) activates SGK1 by phosphorylating threonine residue T256, located in the activation loop of SGK1. Phosphorylation of SGK1 at S422 facilitates subsequent phosphorylation at T256 (Kobayashi and Cohen 1999).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-HSA-6795449" ], "enzyme_list": [ "O15530-1", "O00141-1" ], "evidence": [ { "id": "R-HSA-6795473", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6795473" } ] }, { "id": "R-HSA-9603279", "name": "PIP3 recruits PDK1 and AKT to the membrane", "equation": "", "summary": "Phosphatidylinositides generated by PI3K recruit phosphatidylinositide-dependent protein kinase 1 (PDK1) and AKT (also known as protein kinase B) to the membrane, through their PH (pleckstrin-homology) domains. The binding of PIP3 to the PH domain of AKT is the rate-limiting step in AKT activation. In mammals there are three AKT isoforms (AKT1-3) encoded by three separate genes. The three isoforms share a high degree of amino acid identity and have indistinguishable substrate specificity in vitro. However, isoform-preferred substrates in vivo cannot be ruled out. The relative expression of the three isoforms differs in different mammalian tissues: AKT1 is the predominant isoform in the majority of tissues, AKT2 is the predominant isoform in insulin-responsive tissues, and AKT3 is the predominant isoform in brain and testes. All 3 isoforms are expressed in human and mouse platelets (Yin et al. 2008; O'Brien et al. 2008). Note: all data in the pathway refer to AKT1, which is the most studied.", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "P31749-1", "P31751-1", "Q9Y243-1" ], "evidence": [ { "id": "R-HSA-9603279", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9603279" } ] }, { "id": "R-HSA-9632858", "name": "PRKCZ autophosphorylates downstream of estrogen stimulation", "equation": "", "summary": "PKC zeta (PRKCZ) is serine phosphorylated downstream of ESR1 and estradiol stimulation. Serine phosphorylation is required for recruitment of RAS to the ESR1 complex, the estrogen-stimulated translocation of ERK2 to the nucleus and for entry into S phase (Castoria et al, 2004). Mutation of threonine 410, which is required for PRKCZ activation, abolishes serine phosphorylation, suggesting the enzyme autophosphorylates (Castoria et al, 2004).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1", "Q05513-1" ], "evidence": [ { "id": "R-HSA-9632858", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9632858" } ] }, { "id": "R-HSA-9632906", "name": "PRKCZ recruits RAS in response to estrogen stimulation", "equation": "", "summary": "RAS is recruited to a complex that also contains SRC, PRKCZ and the p85 subunit of PI3K in response to estrogen stimulation (Castoria et al, 2004). RAS signaling downstream of ESR1 contributes to cell cycle progression through the induction of cyclin D transcription and the nuclear export of CDKN1B (Castoria et al, 1999; Castoria et al, 2001; Migliaccio et al, 1996; Rodier et al, 2002; reviewed in Castoria et al, 2010; Arnal et al, 2017).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P01111-1", "O15530-1", "Q05513-1", "P01112-1" ], "evidence": [ { "id": "R-HSA-9632906", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9632906" } ] }, { "id": "R-HSA-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "equation": "", "summary": "MAPK1 (also known as ERK2) translocates to the nucleus in response to estrogen stimulation several cell lines in a manner that also depends on SRC, PI3K and PRCKZ (Castoria et al, 2004). RAS signaling and ERK2 nuclear translocation promotes estrogen-dependent stimulation of cell cycle progression (Castoria et al, 1999; Castoria et al, 2001; Migliaccio et al, 1996; Castoria et al, 2004; Rodier et al, 2002; Foster et al, 2003;reviewed in Castoria et al, 2010).", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P01111-1", "O15530-1", "Q05513-1", "P28482-1", "P01112-1" ], "evidence": [ { "id": "R-HSA-9632910", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9632910" } ] }, { "id": "R-HSA-9632918", "name": "PRKCZ stimulates RAS nucleotide exchange in response to estrogen", "equation": "", "summary": "Estrogen stimulation promotes nucleotide exchange on RAS in a number of cell lines, leading to RAS signaling and cell cycle progression (Atkas et al, 1997; Cheng et al, 1998; Kawada et al, 1997; Castoria et al, 1999; Castoria et al, 2001). RAS activation depends on recruitment of SRC, PI3K and PRKCZ, and the complex likely also includes SOS, although this has not been explicitly demonstrated (Migliaccio et al, 1996; Castoria et al, 2004; reviewed in Castoria et al, 2010).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P01111-1", "O15530-1", "Q05513-1", "P01112-1" ], "evidence": [ { "id": "R-HSA-9632918", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9632918" } ] }, { "id": "R-HSA-9731018", "name": "SARS-CoV-1 M binds to PDPK1", "equation": "", "summary": "SARS-CoV-1 M-protein induces apoptosis through caspase 8 and caspase 9 activation by down-regulating the PKB/Akt survival signalling cascade. Mechanistically M, probably located in the plasma membrane (Tseng et al, 2010), binds to 3-phosphoinositide-dependent protein kinase 1 (PDPK1), inhibiting its phosphorylation activity on the PH domain, preferentially perturbing the activity of any PDK1 downstream substrate whose phosphorylation is mediated through this domain. This mainly affects PKB/Akt activation, which is down-regulated (Chan et al, 2007; Tsoi et al, 2014).", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-9731018", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9731018" } ] }, { "id": "R-HSA-9755777", "name": "SARS-CoV-2 M, N bind to PDPK1", "equation": "", "summary": "SARS-CoV-2 membrane glycoprotein M induced caspase-dependent apoptosis in M-expressing African green monkey kidney epithelial Vero E6 cells and in human liver carcinoma HepG2 cells (Ren Y et al. 2021). The expression of viral M in human embryonic kidney 293T (HEK293T) cells inhibited PKB/AKT signaling pathway and reduced the phosphorylated levels of PKB/AKT, FKHRL1 and ASK. The compromised PKB/AKT activity results in apoptosis via caspase activation. Mechanistically, viral M binds to 3-phosphoinositide-dependent protein kinase 1 (PDPK1 or PDK1), inhibiting its phosphorylation activity on the PH domain. This interection prevented AKT binding to PDPK1 thus down-regulating PDPK1-PKB/AKT signaling (Ren Y et al. 2021). Similar findings were reported for the SARS-CoV-1 M protein (Tsoi H et al. 2014), In addition, SARS-CoV-2 N enhanced M-induced apoptosis by strengthening the interaction between M and PDPK1 (Ren Y et al. 2021).;", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-HSA-9755777", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9755777" } ] }, { "id": "R-NUL-9620024", "name": "PDPK1 phosphorylates Rps6ka2", "equation": "", "summary": "Recombinant human PDPK1 phosphorylates recombinant mouse Rps6ka3 (Rsk2) on serine residue S227 (Jensen et al. 1999).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-MMU-9620028" ], "output_participant_list": [ "R-MMU-9620027" ], "enzyme_list": [ "O15530-1" ], "evidence": [ { "id": "R-NUL-9620024", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-NUL-9620024" } ] } 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"https://www.uniprot.org/uniprot/A0A0B4J2F2" } ] } ] }, { "uniprot_ac": "A0A0B4KHC3", "gene_name": "PKD", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3" } ] } ] }, { "uniprot_ac": "A0A0B4KHT3", "gene_name": "Lrrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3" } ] } ] }, { "uniprot_ac": "A0A0B4KHX7", "gene_name": "Gcn2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHX7" } ] } ] }, { "uniprot_ac": "A0A0G2JUP3", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3" } ] } ] }, { "uniprot_ac": "A0A0G2JVL3", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JVL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JVL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3" } ] } ] }, { "uniprot_ac": "A0A0G2JWX7", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX7" } ] } ] }, { "uniprot_ac": "A0A0G2JXR8", "gene_name": "LOC100911229", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JXR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JXR8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JXR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JXR8" } ] } ] }, { "uniprot_ac": "A0A0G2JZW9", "gene_name": "ENSRNOG00000068522", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9" } ] } ] }, { "uniprot_ac": "A0A0G2K2T8", "gene_name": "RGD1565143", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2T8" } ] } ] }, { "uniprot_ac": "A0A0G2K344", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] } ] }, { "uniprot_ac": "A0A0G2K490", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K490" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K490" } ] } ] }, { "uniprot_ac": "A0A0G2K578", "gene_name": "AABR07068650.1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K578" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K578" } ] } ] }, { "uniprot_ac": "A0A0G2K5C7", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5C7" } ] } ] }, { "uniprot_ac": "A0A0G2K5L3", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K5L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K5L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3" } ] } ] }, { "uniprot_ac": "A0A0G2K6V9", "gene_name": "RGD1564409", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9" } ] } ] }, { "uniprot_ac": "A0A0G2KAH6", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2KAH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2KAH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6" } ] } ] }, { "uniprot_ac": "A0A0G2KB60", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2KB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2KB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KB60" } ] } ] }, { "uniprot_ac": "A0A0G2QC55", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2QC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2QC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55" } ] } ] }, { "uniprot_ac": "A0A140LI04", "gene_name": "Gm5890", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A140LI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LI04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A140LI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LI04" } ] } ] }, { "uniprot_ac": "A0A140LJ87", "gene_name": "Gm4565", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A140LJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LJ87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A140LJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LJ87" } ] } ] }, { "uniprot_ac": "A0A3B2WD63", "gene_name": "Gm7356", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A3B2WD63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3B2WD63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3B2WD63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3B2WD63" } ] } ] }, { "uniprot_ac": "A0A4D6K823", "gene_name": "nmo", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K823" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K823" } ] } ] }, { "uniprot_ac": "A0A6M3Q7C8", "gene_name": "SRPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A6M3Q7C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A6M3Q7C8" } ] } ] }, { "uniprot_ac": "A0A8I5Y7S3", "gene_name": "LOC120097771", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5Y7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7S3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5Y7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7S3" } ] } ] }, { "uniprot_ac": "A0A8I5Y8C3", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5Y8C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5Y8C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8C3" } ] } ] }, { "uniprot_ac": "A0A8I5ZKJ9", "gene_name": "ENSRNOG00000070867", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZKJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZKJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKJ9" } ] } ] }, { "uniprot_ac": "A0A8I5ZLV4", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLV4" } ] } ] }, { "uniprot_ac": "A0A8I5ZMP0", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP0" } ] } ] }, { "uniprot_ac": "A0A8I5ZN46", "gene_name": "LOC108353138", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN46" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN46" } ] } ] }, { "uniprot_ac": "A0A8I5ZNK2", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZNK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZNK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNK2" } ] } ] }, { "uniprot_ac": "A0A8I5ZP97", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8I5ZP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97" } ] } ] }, { "uniprot_ac": "A0A8I5ZR62", "gene_name": "RGD1565071", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] } ] }, { "uniprot_ac": "A0A8I5ZS27", "gene_name": "LOC102555239", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZS27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZS27" } ] } ] }, { "uniprot_ac": "A0A8I5ZSS7", "gene_name": "LOC102546375", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSS7" } ] } ] }, { "uniprot_ac": "A0A8I5ZT61", "gene_name": "LOC300308", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT61" } ] } ] }, { "uniprot_ac": "A0A8I5ZUS1", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUS1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8I5ZUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUS1" } ] } ] }, { "uniprot_ac": "A0A8I5ZUX6", "gene_name": "RGD1566007", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZUX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZUX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUX6" } ] } ] }, { "uniprot_ac": "A0A8I5ZV60", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV60" } ] } ] }, { "uniprot_ac": "A0A8I5ZYM4", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] } ] }, { "uniprot_ac": "A0A8I5ZZZ6", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZZZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZZZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ6" } ] } ] }, { "uniprot_ac": "A0A8I6A0F8", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A0F8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A0F8" } ] } ] }, { "uniprot_ac": "A0A8I6A165", "gene_name": "LOC120093114", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A165" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A165" } ] } ] }, { "uniprot_ac": "A0A8I6A1U5", "gene_name": "LOC120093094", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1U5" } ] } ] }, { "uniprot_ac": "A0A8I6A574", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A574" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A574" } ] } ] }, { "uniprot_ac": "A0A8I6A7D1", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A7D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A7D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7D1" } ] } ] }, { "uniprot_ac": "A0A8I6A7V5", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7V5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8I6A7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7V5" } ] } ] }, { "uniprot_ac": "A0A8I6A8U4", "gene_name": "ENSRNOG00000066428", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A8U4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A8U4" } ] } ] }, { "uniprot_ac": "A0A8I6A9X0", "gene_name": "LOC120100104", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A9X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A9X0" } ] } ] }, { "uniprot_ac": "A0A8I6AAX5", "gene_name": "LOC120099682", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AAX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AAX5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AAX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AAX5" } ] } ] }, { "uniprot_ac": "A0A8I6ACE8", "gene_name": "LOC100910657", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACE8" } ] } ] }, { "uniprot_ac": "A0A8I6ACR1", "gene_name": "ENSRNOG00000067256", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ACR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACR1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ACR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACR1" } ] } ] }, { "uniprot_ac": "A0A8I6AD01", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AD01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AD01" } ] } ] }, { "uniprot_ac": "A0A8I6AEL0", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AEL0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8I6AEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AEL0" } ] } ] }, { "uniprot_ac": "A0A8I6AHQ6", "gene_name": "Nek2l1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AHQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AHQ6" } ] } ] }, { "uniprot_ac": "A0A8I6AJD2", "gene_name": "LOC103690174", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AJD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AJD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJD2" } ] } ] }, { "uniprot_ac": "A0A8I6AJX5", "gene_name": "RGD1561440", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJX5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8I6AJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJX5" } ] } ] }, { "uniprot_ac": "A0A8I6ANX6", "gene_name": "Dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ANX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ANX6" } ] } ] }, { "uniprot_ac": "A0A8I6AQN6", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQN6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQN6" } ] } ] }, { "uniprot_ac": "A0A8I6ATH0", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ATH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ATH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATH0" } ] } ] }, { "uniprot_ac": "A0A8I6ATM1", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ATM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATM1" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8I6ATM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATM1" } ] } ] }, { "uniprot_ac": "A0A8I6AUJ4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AUJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AUJ4" } ] } ] }, { "uniprot_ac": "A0A8I6AWX7", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8I6AWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7" } ] } ] }, { "uniprot_ac": "A0A8I6G1H3", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G1H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G1H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3" } ] } ] }, { "uniprot_ac": "A0A8I6G5Z0", "gene_name": "AABR07072539.5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Z0" } ] } ] }, { "uniprot_ac": "A0A8I6G980", "gene_name": "LOC100911984", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G980" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G980" } ] } ] }, { "uniprot_ac": "A0A8I6GBQ0", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GBQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GBQ0" } ] } ] }, { "uniprot_ac": "A0A8I6GDY5", "gene_name": "RGD1564651", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GDY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GDY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GDY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GDY5" } ] } ] }, { "uniprot_ac": "A0A8I6GI15", "gene_name": "RGD1560718", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GI15" } ] } ] }, { "uniprot_ac": "A0A8I6GJV1", "gene_name": "ENSRNOG00000069390", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJV1" } ] } ] }, { "uniprot_ac": "A0A8I6GK16", "gene_name": "LOC102549716", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK16" } ] } ] }, { "uniprot_ac": "A0A8I6GK52", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK52" } ] } ] }, { "uniprot_ac": "A0A8I6GKS8", "gene_name": "LOC120093063", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKS8" } ] } ] }, { "uniprot_ac": "A0A8I6GM03", "gene_name": "LOC685793", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GM03" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GM03" } ] } ] }, { "uniprot_ac": "A0A8J8XEH6", "gene_name": "ENSRNOG00000067334", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8J8XEH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8J8XEH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8J8XEH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8J8XEH6" } ] } ] }, { "uniprot_ac": "A0AUV4", "gene_name": "Gm7168", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0AUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0AUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0AUV4" } ] } ] }, { "uniprot_ac": "A1A5Q6", "gene_name": "Smok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1A5Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1A5Q6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1A5Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1A5Q6" } ] } ] }, { "uniprot_ac": "A1Z7T0", "gene_name": "Pkn", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] } ] }, { "uniprot_ac": "A1Z9X0", "gene_name": "aPKC", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z9X0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z9X0" } ] } ] }, { "uniprot_ac": "A1ZBC4", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] } ] }, { "uniprot_ac": "A1ZBH7", "gene_name": "hppy", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBH7" } ] } ] }, { "uniprot_ac": "A1ZBL9", "gene_name": "par-1", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] } ] }, { "uniprot_ac": "A2AAJ9", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AAJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AAJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2AAJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AAJ9" } ] } ] }, { "uniprot_ac": "A2AQW0", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQW0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2AQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQW0" } ] } ] }, { "uniprot_ac": "A2AQX6", "gene_name": "Gm14151", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AQX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2AQX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQX6" } ] } ] }, { "uniprot_ac": "A2ASS6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2ASS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ASS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2ASS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ASS6" } ] } ] }, { "uniprot_ac": "A2CG49", "gene_name": "Kalrn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2CG49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2CG49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2CG49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2CG49" } ] } ] }, { "uniprot_ac": "A2KF29", "gene_name": "Smoktcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2KF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2KF29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2KF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2KF29" } ] } ] }, { "uniprot_ac": "A4L9P5", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A4L9P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4L9P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4L9P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4L9P5" } ] } ] }, { "uniprot_ac": "A4VCL2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4VCL2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4VCL2" } ] } ] }, { "uniprot_ac": "A6HK01", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A6HK01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HK01" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A6HK01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HK01" } ] } ] }, { "uniprot_ac": "A6KB61", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A6KB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KB61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A6KB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KB61" } ] } ] }, { "uniprot_ac": "B0G126", "gene_name": "pip5k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] } ] }, { "uniprot_ac": "B0LT89", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B0LT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0LT89" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0LT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0LT89" } ] } ] }, { "uniprot_ac": "B1WBT4", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B1WBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B1WBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBT4" } ] } ] }, { "uniprot_ac": "B1WBU5", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B1WBU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B1WBU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBU5" } ] } ] }, { "uniprot_ac": "B2DD29", "gene_name": "Brsk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] } ] }, { "uniprot_ac": "B2GUY1", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B2GUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUY1" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "B2GUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUY1" } ] } ] }, { "uniprot_ac": "B5DFG1", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B5DFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B5DFG1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B5DFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B5DFG1" } ] } ] }, { "uniprot_ac": "C0HKC8", "gene_name": "Smok3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "C0HKC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C0HKC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC8" } ] } ] }, { "uniprot_ac": "C0HKC9", "gene_name": "Smok3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "C0HKC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C0HKC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC9" } ] } ] }, { "uniprot_ac": "D3Z822", "gene_name": "Atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z822" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z822" } ] } ] }, { "uniprot_ac": "D3Z837", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z837" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z837" } ] } ] }, { "uniprot_ac": "D3Z8E0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8E0" } ] } ] }, { "uniprot_ac": "D3Z8I4", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8I4" } ] } ] }, { "uniprot_ac": "D3ZBE5", "gene_name": "Nek7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZBE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBE5" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "D3ZBE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBE5" } ] } ] }, { "uniprot_ac": "D3ZBS8", "gene_name": "LOC690235", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZBS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZBS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBS8" } ] } ] }, { "uniprot_ac": "D3ZCD7", "gene_name": "Tp53rkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZCD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZCD7" } ] } ] }, { "uniprot_ac": "D3ZD18", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD18" } ] } ] }, { "uniprot_ac": "D3ZDM6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZDM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDM6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "D3ZDM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDM6" } ] } ] }, { "uniprot_ac": "D3ZEK4", "gene_name": "Tssk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEK4" } ] } ] }, { "uniprot_ac": "D3ZFL3", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZFL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFL3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZFL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFL3" } ] } ] }, { "uniprot_ac": "D3ZG83", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG83" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG83" } ] } ] }, { "uniprot_ac": "D3ZGQ5", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZGQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZGQ5" } ] } ] }, { "uniprot_ac": "D3ZHL6", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHL6" } ] } ] }, { "uniprot_ac": "D3ZHP7", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHP7" } ] } ] }, { "uniprot_ac": "D3ZJ84", "gene_name": "Tssk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJ84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJ84" } ] } ] }, { "uniprot_ac": "D3ZL21", "gene_name": "Tp53rka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZL21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZL21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZL21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZL21" } ] } ] }, { "uniprot_ac": "D3ZMG0", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZMG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZMG0" } ] } ] }, { "uniprot_ac": "D3ZML2", "gene_name": "Brsk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] } ] }, { "uniprot_ac": "D3ZQN8", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZQN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZQN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQN8" } ] } ] }, { "uniprot_ac": "D3ZRJ7", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZRJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZRJ7" } ] } ] }, { "uniprot_ac": "D3ZSB7", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSB7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSB7" } ] } ] }, { "uniprot_ac": "D3ZSY9", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZSY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSY9" } ] } ] }, { "uniprot_ac": "D3ZSZ3", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSZ3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "D3ZSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSZ3" } ] } ] }, { "uniprot_ac": "D3ZTD1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZTD1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZTD1" } ] } ] }, { "uniprot_ac": "D3ZXB1", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZXB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZXB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZXB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZXB1" } ] } ] }, { "uniprot_ac": "D3ZY07", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZY07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZY07" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "D3ZY07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZY07" } ] } ] }, { "uniprot_ac": "D3ZZK7", "gene_name": "Myo3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZK7" } ] } ] }, { "uniprot_ac": "D4A229", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A229" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "D4A229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A229" } ] } ] }, { "uniprot_ac": "D4A280", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A280" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A280" } ] } ] }, { "uniprot_ac": "D4A355", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A355" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A355" } ] } ] }, { "uniprot_ac": "D4A3D9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3D9" } ] } ] }, { "uniprot_ac": "D4A3H8", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3H8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3H8" } ] } ] }, { "uniprot_ac": "D4A454", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A454" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D4A454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A454" } ] } ] }, { "uniprot_ac": "D4A6T6", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A6T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A6T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T6" } ] } ] }, { "uniprot_ac": "D4A6T9", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A6T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A6T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T9" } ] } ] }, { "uniprot_ac": "D4A7V9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7V9" } ] } ] }, { "uniprot_ac": "D4A949", "gene_name": "Smokl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A949" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A949" } ] } ] }, { "uniprot_ac": "D4A9H8", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A9H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A9H8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A9H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A9H8" } ] } ] }, { "uniprot_ac": "D4ACL8", "gene_name": "Atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4ACL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACL8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4ACL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACL8" } ] } ] }, { "uniprot_ac": "D4AD76", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AD76" } ] } ] }, { "uniprot_ac": "D4AE24", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AE24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AE24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE24" } ] } ] }, { "uniprot_ac": "D4AE59", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AE59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AE59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE59" } ] } ] }, { "uniprot_ac": "E9PSK5", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSK5" } ] } ] }, { "uniprot_ac": "E9PSL7", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSL7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSL7" } ] } ] }, { "uniprot_ac": "E9PSM2", "gene_name": "LOC301165", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSM2" } ] } ] }, { "uniprot_ac": "E9PTG8", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTG8" } ] } ] }, { "uniprot_ac": "E9Q3S4", "gene_name": "Map3k19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9Q3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9Q3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q3S4" } ] } ] }, { "uniprot_ac": "F1LNJ1", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LNJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LNJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ1" } ] } ] }, { "uniprot_ac": "F1LNN8", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNN8" } ] } ] }, { "uniprot_ac": "F1LP90", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP90" } ] } ] }, { "uniprot_ac": "F1LRA7", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LRA7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1LRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LRA7" } ] } ] }, { "uniprot_ac": "F1LTP9", "gene_name": "LOC120093110", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTP9" } ] } ] }, { "uniprot_ac": "F1LUY7", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LUY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUY7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1LUY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUY7" } ] } ] }, { "uniprot_ac": "F1LWF2", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWF2" } ] } ] }, { "uniprot_ac": "F1LWJ6", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWJ6" } ] } ] }, { "uniprot_ac": "F1LXF1", "gene_name": "Bcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LXF1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LXF1" } ] } ] }, { "uniprot_ac": "F1LYY7", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LYY7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1LYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LYY7" } ] } ] }, { "uniprot_ac": "F1M0Z1", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M0Z1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M0Z1" } ] } ] }, { "uniprot_ac": "F1M419", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M419" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M419" } ] } ] }, { "uniprot_ac": "F1M7G0", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7G0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M7G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7G0" } ] } ] }, { "uniprot_ac": "F1M7N7", "gene_name": "Rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7N7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M7N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7N7" } ] } ] }, { "uniprot_ac": "F1M7Y5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7Y5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1M7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7Y5" } ] } ] }, { "uniprot_ac": "F1M9D0", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9D0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1M9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9D0" } ] } ] }, { "uniprot_ac": "F7FMK8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F7FMK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7FMK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F7FMK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7FMK8" } ] } ] }, { "uniprot_ac": "G3V783", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] } ] }, { "uniprot_ac": "J3KMT3", "gene_name": "Gm6882", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "J3KMT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3KMT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "J3KMT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3KMT3" } ] } ] }, { "uniprot_ac": "J3QK59", "gene_name": "Gm6176", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "J3QK59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3QK59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "J3QK59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3QK59" } ] } ] }, { "uniprot_ac": "M0R777", "gene_name": "LOC102551633", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0R777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R777" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0R777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R777" } ] } ] }, { "uniprot_ac": "M0R7E7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0R7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R7E7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "M0R7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R7E7" } ] } ] }, { "uniprot_ac": "M0RBT0", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RBT0" } ] } ] }, { "uniprot_ac": "M0RD40", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD40" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD40" } ] } ] }, { "uniprot_ac": "M0RD88", "gene_name": "Smok2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD88" } ] } ] }, { "uniprot_ac": "M0RDM0", "gene_name": "LOC103689976", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RDM0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RDM0" } ] } ] }, { "uniprot_ac": "M9NGC6", "gene_name": "Srpk79D", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9NGC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9NGC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9NGC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9NGC6" } ] } ] }, { "uniprot_ac": "M9PGC5", "gene_name": "Wnk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PGC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PGC5" } ] } ] }, { "uniprot_ac": "M9PI41", "gene_name": "sti", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI41" } ] } ] }, { "uniprot_ac": "O00141", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00141" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00141" } ] } ] }, { "uniprot_ac": "O00311", "gene_name": "CDC7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00311", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00311" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00311", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00311" } ] } ] }, { "uniprot_ac": "O00444", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00444" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O00444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00444" } ] } ] }, { "uniprot_ac": "O00506", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00506" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00506" } ] } ] }, { "uniprot_ac": "O08605", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08605" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08605" } ] } ] }, { "uniprot_ac": "O08648", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08648" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O08648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08648" } ] } ] }, { "uniprot_ac": "O08678", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] } ] }, { "uniprot_ac": "O08679", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] } ] }, { "uniprot_ac": "O08815", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08815" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08815" } ] } ] }, { "uniprot_ac": "O08874", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08874" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "O08874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08874" } ] } ] }, { "uniprot_ac": "O08875", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08875" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08875" } ] } ] }, { "uniprot_ac": "O08901", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08901" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08901" } ] } ] }, { "uniprot_ac": "O08911", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08911" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O08911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08911" } ] } ] }, { "uniprot_ac": "O09110", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O09110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09110" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O09110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09110" } ] } ] }, { "uniprot_ac": "O14578", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14578" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14578" } ] } ] }, { "uniprot_ac": "O14730", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14730" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14730" } ] } ] }, { "uniprot_ac": "O14733", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14733" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O14733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14733" } ] } ] }, { "uniprot_ac": "O14757", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14757" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14757" } ] } ] }, { "uniprot_ac": "O14874", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] } ] }, { "uniprot_ac": "O14920", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] } ] }, { "uniprot_ac": "O14936", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14936" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14936" } ] } ] }, { "uniprot_ac": "O14965", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14965" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14965" } ] } ] }, { "uniprot_ac": "O14976", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14976" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14976" } ] } ] }, { "uniprot_ac": "O15021", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15021" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15021" } ] } ] }, { "uniprot_ac": "O15075", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15075", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15075" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15075", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15075" } ] } ] }, { "uniprot_ac": "O15111", "gene_name": "CHUK", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O15111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15111" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O15111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15111" } ] } ] }, { "uniprot_ac": "O15264", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15264" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O15264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15264" } ] } ] }, { "uniprot_ac": "O15530", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15530" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15530" } ] } ] }, { "uniprot_ac": "O35099", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35099" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O35099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35099" } ] } ] }, { "uniprot_ac": "O35280", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35280" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O35280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35280" } ] } ] }, { "uniprot_ac": "O35491", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35491" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35491" } ] } ] }, { "uniprot_ac": "O35492", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35492" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35492" } ] } ] }, { "uniprot_ac": "O35493", "gene_name": "Clk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35493" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35493" } ] } ] }, { "uniprot_ac": "O35495", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35495" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35495" } ] } ] }, { "uniprot_ac": "O35831", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35831" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35831" } ] } ] }, { "uniprot_ac": "O35832", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35832" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35832" } ] } ] }, { "uniprot_ac": "O35942", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35942" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O35942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35942" } ] } ] }, { "uniprot_ac": "O43283", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43283" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O43283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43283" } ] } ] }, { "uniprot_ac": "O43293", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43293" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43293" } ] } ] }, { "uniprot_ac": "O43318", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43318" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O43318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43318" } ] } ] }, { "uniprot_ac": "O43353", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] } ] }, { "uniprot_ac": "O43683", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43683" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43683" } ] } ] }, { "uniprot_ac": "O43781", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43781" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O43781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43781" } ] } ] }, { "uniprot_ac": "O43930", "gene_name": "PRKY", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43930" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43930" } ] } ] }, { "uniprot_ac": "O54748", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54748" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54748" } ] } ] }, { "uniprot_ac": "O54781", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54781" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54781" } ] } ] }, { "uniprot_ac": "O54784", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54784" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54784" } ] } ] }, { "uniprot_ac": "O54785", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54785" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54785" } ] } ] }, { "uniprot_ac": "O54833", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54833" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54833" } ] } ] }, { "uniprot_ac": "O54863", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54863" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54863" } ] } ] }, { "uniprot_ac": "O54874", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54874" } ] } ] }, { "uniprot_ac": "O54949", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54949" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O54949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54949" } ] } ] }, { "uniprot_ac": "O54967", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] } ] }, { "uniprot_ac": "O54988", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54988", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54988" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54988", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54988" } ] } ] }, { "uniprot_ac": "O54992", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54992" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54992" } ] } ] }, { "uniprot_ac": "O55028", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] } ] }, { "uniprot_ac": "O55047", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55047" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55047" } ] } ] }, { "uniprot_ac": "O55098", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] } ] }, { "uniprot_ac": "O55099", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55099" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55099" } ] } ] }, { "uniprot_ac": "O55173", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55173" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55173" } ] } ] }, { "uniprot_ac": "O55222", "gene_name": "Ilk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55222" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55222" } ] } ] }, { "uniprot_ac": "O60229", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60229" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60229" } ] } ] }, { "uniprot_ac": "O60285", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60285" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60285" } ] } ] }, { "uniprot_ac": "O60307", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60307" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60307" } ] } ] }, { "uniprot_ac": "O60566", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60566" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60566" } ] } ] }, { "uniprot_ac": "O61122", "gene_name": "svkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61122" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61122" } ] } ] }, { "uniprot_ac": "O61125", "gene_name": "krsA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61125" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61125" } ] } ] }, { "uniprot_ac": "O61267", "gene_name": "lok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61443" } ] } ] }, { "uniprot_ac": "O61444", "gene_name": "Mkk4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61444" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O61444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61444" } ] } ] }, { "uniprot_ac": "O61661", "gene_name": "grp", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61661" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61661" } ] } ] }, { "uniprot_ac": "O62602", "gene_name": "lic", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O62602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62602" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O62602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62602" } ] } ] }, { "uniprot_ac": "O62618", "gene_name": "p38a", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62618" } ] } ] }, { "uniprot_ac": "O70126", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70126" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70126" } ] } ] }, { "uniprot_ac": "O70146", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70146" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O70146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70146" } ] } ] }, { "uniprot_ac": "O70150", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70150" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "O70150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70150" } ] } ] }, { "uniprot_ac": "O70405", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70405" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70405" } ] } ] }, { "uniprot_ac": "O70444", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70444" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70444" } ] } ] }, { "uniprot_ac": "O70551", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70551" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70551" } ] } ] }, { "uniprot_ac": "O70589", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70589" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70589" } ] } ] }, { "uniprot_ac": "O75116", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75116" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75116" } ] } ] }, { "uniprot_ac": "O75385", "gene_name": "ULK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75385" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75385" } ] } ] }, { "uniprot_ac": "O75460", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] } ] }, { "uniprot_ac": "O75582", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75582", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75582" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75582", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75582" } ] } ] }, { "uniprot_ac": "O75676", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75676" } ] } ] }, { "uniprot_ac": "O75716", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] } ] }, { "uniprot_ac": "O75914", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75914" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75914" } ] } ] }, { "uniprot_ac": "O75962", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75962" } ] } ] }, { "uniprot_ac": "O76039", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O76039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76039" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O76039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76039" } ] } ] }, { "uniprot_ac": "O76324", "gene_name": "dco", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76324" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76324" } ] } ] }, { "uniprot_ac": "O88351", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] } ] }, { "uniprot_ac": "O88445", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88445" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88445" } ] } ] }, { "uniprot_ac": "O88506", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88506" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88506" } ] } ] }, { "uniprot_ac": "O88643", "gene_name": "Pak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88643" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88643" } ] } ] }, { "uniprot_ac": "O88664", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88664" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88664" } ] } ] }, { "uniprot_ac": "O88697", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] } ] }, { "uniprot_ac": "O88764", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88764" } ] } ] }, { "uniprot_ac": "O88831", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88831" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "O88831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88831" } ] } ] }, { "uniprot_ac": "O88850", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88850" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88850" } ] } ] }, { "uniprot_ac": "O88866", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88866" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88866" } ] } ] }, { "uniprot_ac": "O88904", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88904", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88904" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88904", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88904" } ] } ] }, { "uniprot_ac": "O94768", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94768" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O94768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94768" } ] } ] }, { "uniprot_ac": "O94804", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94804" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O94804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94804" } ] } ] }, { "uniprot_ac": "O94806", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94806" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "O94806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94806" } ] } ] }, { "uniprot_ac": "O94921", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94921" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O94921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94921" } ] } ] }, { "uniprot_ac": "O95382", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95382" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O95382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95382" } ] } ] }, { "uniprot_ac": "O95747", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95747" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95747" } ] } ] }, { "uniprot_ac": "O95819", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95819" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95819" } ] } ] }, { "uniprot_ac": "O95835", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95835" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95835" } ] } ] }, { "uniprot_ac": "O96013", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O96013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96013" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O96013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96013" } ] } ] }, { "uniprot_ac": "O96017", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O96017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96017" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O96017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96017" } ] } ] }, { "uniprot_ac": "O97143", "gene_name": "SAK", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97143" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97143" } ] } ] }, { "uniprot_ac": "P00536", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00536" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00536" } ] } ] }, { "uniprot_ac": "P00539", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00539" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00539" } ] } ] }, { "uniprot_ac": "P00540", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00540" } ] } ] }, { "uniprot_ac": "P00546", "gene_name": "CDC28", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00546" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P00546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00546" } ] } ] }, { "uniprot_ac": "P01111", "gene_name": "NRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P01111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P01111" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P01111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P01111" } ] } ] }, { "uniprot_ac": "P01112", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P01112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P01112" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P01112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P01112" } ] } ] }, { "uniprot_ac": "P04049", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04049" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04049" } ] } ] }, { "uniprot_ac": "P04627", "gene_name": "Araf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P04627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04627" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P04627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04627" } ] } ] }, { "uniprot_ac": "P05129", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05129" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05129" } ] } ] }, { "uniprot_ac": "P05130", "gene_name": "Pkc53E", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05130" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05130" } ] } ] }, { "uniprot_ac": "P05132", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05132" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05132" } ] } ] }, { "uniprot_ac": "P05696", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05696" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05696" } ] } ] }, { "uniprot_ac": "P05771", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05771" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05771" } ] } ] }, { "uniprot_ac": "P05986", "gene_name": "TPK3", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05986" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05986" } ] } ] }, { "uniprot_ac": "P06243", "gene_name": "CDC7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06243" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06243" } ] } ] }, { "uniprot_ac": "P06244", "gene_name": "TPK1", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06244" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P06244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06244" } ] } ] }, { "uniprot_ac": "P06245", "gene_name": "TPK2", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06245" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P06245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06245" } ] } ] }, { "uniprot_ac": "P06493", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] } ] }, { "uniprot_ac": "P06782", "gene_name": "SNF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06782" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06782" } ] } ] }, { "uniprot_ac": "P06784", "gene_name": "STE7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06784" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P06784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06784" } ] } ] }, { "uniprot_ac": "P06803", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06803" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06803" } ] } ] }, { "uniprot_ac": "P07934", "gene_name": "Phkg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] } ] }, { "uniprot_ac": "P08018", "gene_name": "PBS2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08018" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P08018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08018" } ] } ] }, { "uniprot_ac": "P08181", "gene_name": "CkIIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08181" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08181" } ] } ] }, { "uniprot_ac": "P08413", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08413" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P08413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08413" } ] } ] }, { "uniprot_ac": "P08414", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08414" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P08414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08414" } ] } ] }, { "uniprot_ac": "P08458", "gene_name": "SPS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08458" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08458" } ] } ] }, { "uniprot_ac": "P09215", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] } ] }, { "uniprot_ac": "P09216", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09216" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09216" } ] } ] }, { "uniprot_ac": "P09217", "gene_name": "Prkcz", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09217" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09217" } ] } ] }, { "uniprot_ac": "P0C0R5", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C0R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C0R5" } ] } ] }, { "uniprot_ac": "P0C1X8", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C1X8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C1X8" } ] } ] }, { "uniprot_ac": "P0C263", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C263" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C263" } ] } ] }, { "uniprot_ac": "P0C264", "gene_name": "SBK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C264" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C264" } ] } ] }, { "uniprot_ac": "P0C5K0", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K0" } ] } ] }, { "uniprot_ac": "P0C5K1", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K1" } ] } ] }, { "uniprot_ac": "P0C605", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C605" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P0C605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C605" } ] } ] }, { "uniprot_ac": "P0C865", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C865", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C865" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P0C865", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C865" } ] } ] }, { "uniprot_ac": "P0C8E4", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C8E4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P0C8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C8E4" } ] } ] }, { "uniprot_ac": "P0CD62", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0CD62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CD62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0CD62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CD62" } ] } ] }, { "uniprot_ac": "P10398", "gene_name": "ARAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P10398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10398" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10398" } ] } ] }, { "uniprot_ac": "P10676", "gene_name": "ninaC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10676" } ] } ] }, { "uniprot_ac": "P11274", "gene_name": "BCR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11274" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11274" } ] } ] }, { "uniprot_ac": "P11275", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11275" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11275" } ] } ] }, { "uniprot_ac": "P11309", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11309" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11309" } ] } ] }, { "uniprot_ac": "P11345", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11345" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11345" } ] } ] }, { "uniprot_ac": "P11346", "gene_name": "Raf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11346" } ] } ] }, { "uniprot_ac": "P11440", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] } ] }, { "uniprot_ac": "P11730", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11730" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11730" } ] } ] }, { "uniprot_ac": "P11792", "gene_name": "SCH9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11792" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11792" } ] } ] }, { "uniprot_ac": "P11798", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11798" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11798" } ] } ] }, { "uniprot_ac": "P11801", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11801" } ] } ] }, { "uniprot_ac": "P11802", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11802" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P11802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11802" } ] } ] }, { "uniprot_ac": "P11980", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] } ] }, { "uniprot_ac": "P12370", "gene_name": "Pka-C1", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12370" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12370" } ] } ] }, { "uniprot_ac": "P12688", "gene_name": "YPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P12688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12688" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P12688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12688" } ] } ] }, { "uniprot_ac": "P13185", "gene_name": "KIN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P13185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13185" } ] } ] }, { "uniprot_ac": "P13186", "gene_name": "KIN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13186" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P13186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13186" } ] } ] }, { "uniprot_ac": "P13234", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13234" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P13234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13234" } ] } ] }, { "uniprot_ac": "P13286", "gene_name": "Phkg1", "activity": [ { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] } ] }, { "uniprot_ac": "P13677", "gene_name": "inaC", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13677" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13677" } ] } ] }, { "uniprot_ac": "P13678", "gene_name": "Pkc98E", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13678" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13678" } ] } ] }, { "uniprot_ac": "P14056", "gene_name": "Araf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14056" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P14056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14056" } ] } ] }, { "uniprot_ac": "P14618", "gene_name": "PKM", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] } ] }, { "uniprot_ac": "P14680", "gene_name": "YAK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14680" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14680" } ] } ] }, { "uniprot_ac": "P14681", "gene_name": "KSS1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14681" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P14681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14681" } ] } ] }, { "uniprot_ac": "P15056", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15056" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15056" } ] } ] }, { "uniprot_ac": "P15442", "gene_name": "GCN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15442" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15442" } ] } ] }, { "uniprot_ac": "P15790", "gene_name": "CKA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15790" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15790" } ] } ] }, { "uniprot_ac": "P15791", "gene_name": "Camk2d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15791" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P15791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15791" } ] } ] }, { "uniprot_ac": "P16054", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16054" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P16054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16054" } ] } ] }, { "uniprot_ac": "P16892", "gene_name": "FUS3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16892" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P16892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16892" } ] } ] }, { "uniprot_ac": "P16911", "gene_name": "Pka-C2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] } ] }, { "uniprot_ac": "P16912", "gene_name": "Pka-C3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16912" } ] } ] }, { "uniprot_ac": "P17157", "gene_name": "PHO85", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17157" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P17157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17157" } ] } ] }, { "uniprot_ac": "P17252", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17252" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P17252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17252" } ] } ] }, { "uniprot_ac": "P17612", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17612" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P17612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17612" } ] } ] }, { "uniprot_ac": "P18265", "gene_name": "Gsk3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] } ] }, { "uniprot_ac": "P18266", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] } ] }, { "uniprot_ac": "P18431", "gene_name": "sgg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18431" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18431" } ] } ] }, { "uniprot_ac": "P18653", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18653", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18653" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18653", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18653" } ] } ] }, { "uniprot_ac": "P18654", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18654" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18654" } ] } ] }, { "uniprot_ac": "P18961", "gene_name": "YPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18961", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18961" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18961", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18961" } ] } ] }, { "uniprot_ac": "P19139", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19139" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19139" } ] } ] }, { "uniprot_ac": "P19454", "gene_name": "CKA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19454" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19454" } ] } ] }, { "uniprot_ac": "P19525", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] } ] }, { "uniprot_ac": "P19784", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19784" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19784" } ] } ] }, { "uniprot_ac": "P20444", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20444" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P20444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20444" } ] } ] }, { "uniprot_ac": "P20793", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20793" } ] } ] }, { "uniprot_ac": "P20794", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20794" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20794" } ] } ] }, { "uniprot_ac": "P21127", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21127" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P21127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21127" } ] } ] }, { "uniprot_ac": "P21675", "gene_name": "TAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] } ] }, { "uniprot_ac": "P21708", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21708" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P21708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21708" } ] } ] }, { "uniprot_ac": "P21965", "gene_name": "MCK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21965" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P21965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21965" } ] } ] }, { "uniprot_ac": "P22204", "gene_name": "DBF2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22204" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22204" } ] } ] }, { "uniprot_ac": "P22209", "gene_name": "KIN3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22209" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22209" } ] } ] }, { "uniprot_ac": "P22211", "gene_name": "NPR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22211", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22211" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22211", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22211" } ] } ] }, { "uniprot_ac": "P22216", "gene_name": "RAD53", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22216" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P22216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22216" } ] } ] }, { "uniprot_ac": "P22219", "gene_name": "VPS15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22219", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22219" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22219", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22219" } ] } ] }, { "uniprot_ac": "P22517", "gene_name": "CMK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22517" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P22517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22517" } ] } ] }, { "uniprot_ac": "P22518", "gene_name": "Clk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22518" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P22518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22518" } ] } ] }, { "uniprot_ac": "P22612", "gene_name": "PRKACG", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22612" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P22612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22612" } ] } ] }, { "uniprot_ac": "P22694", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22694" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P22694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22694" } ] } ] }, { "uniprot_ac": "P23291", "gene_name": "YCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23291", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23291" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23291", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23291" } ] } ] }, { "uniprot_ac": "P23292", "gene_name": "YCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23292" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23292" } ] } ] }, { "uniprot_ac": "P23293", "gene_name": "SGV1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] } ] }, { "uniprot_ac": "P23298", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23298" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P23298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23298" } ] } ] }, { "uniprot_ac": "P23443", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23443" } ] } ] }, { "uniprot_ac": "P23561", "gene_name": "STE11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23561" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P23561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23561" } ] } ] }, { "uniprot_ac": "P23572", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] } ] }, { "uniprot_ac": "P23573", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] } ] }, { "uniprot_ac": "P23647", "gene_name": "fu", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23647" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23647" } ] } ] }, { "uniprot_ac": "P24583", "gene_name": "PKC1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24583" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P24583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24583" } ] } ] }, { "uniprot_ac": "P24719", "gene_name": "MEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24719" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P24719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24719" } ] } ] }, { "uniprot_ac": "P24723", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24723" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P24723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24723" } ] } ] }, { "uniprot_ac": "P24788", "gene_name": "Cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24788" } ] } ] }, { "uniprot_ac": "P24941", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24941" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P24941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24941" } ] } ] }, { "uniprot_ac": "P25333", "gene_name": "SAT4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25333" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25333" } ] } ] }, { "uniprot_ac": "P25341", "gene_name": "KIN82", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25341", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25341" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25341", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25341" } ] } ] }, { "uniprot_ac": "P25389", "gene_name": "KCC4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25389" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25389" } ] } ] }, { "uniprot_ac": "P25390", "gene_name": "SSK22", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25390", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25390" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25390", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25390" } ] } ] }, { "uniprot_ac": "P26794", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P26794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26794" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P26794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26794" } ] } ] }, { "uniprot_ac": "P27361", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27361" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P27361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27361" } ] } ] }, { "uniprot_ac": "P27448", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27448" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P27448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27448" } ] } ] }, { "uniprot_ac": "P27466", "gene_name": "CMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27466" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P27466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27466" } ] } ] }, { "uniprot_ac": "P27636", "gene_name": "CDC15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27636" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P27636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27636" } ] } ] }, { "uniprot_ac": "P27704", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27704" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P27704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27704" } ] } ] }, { "uniprot_ac": "P27791", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27791" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P27791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27791" } ] } ] }, { "uniprot_ac": "P28028", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28028" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28028" } ] } ] }, { "uniprot_ac": "P28178", "gene_name": "pkgB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28178" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28178" } ] } ] }, { "uniprot_ac": "P28482", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28482" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P28482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28482" } ] } ] }, { "uniprot_ac": "P28652", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28652" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P28652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28652" } ] } ] }, { "uniprot_ac": "P28708", "gene_name": "PRR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28708" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28708" } ] } ] }, { "uniprot_ac": "P28867", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] }, { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] } ] }, { "uniprot_ac": "P29295", "gene_name": "HRR25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P29295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29295" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P29295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29295" } ] } ] }, { "uniprot_ac": "P30285", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P30285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30285" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P30285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30285" } ] } ] }, { "uniprot_ac": "P31152", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31152" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P31152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31152" } ] } ] }, { "uniprot_ac": "P31374", "gene_name": "PSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31374" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31374" } ] } ] }, { "uniprot_ac": "P31749", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31749" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31749" } ] } ] }, { "uniprot_ac": "P31750", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31750" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31750" } ] } ] }, { "uniprot_ac": "P31751", "gene_name": "AKT2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31751" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31751" } ] } ] }, { "uniprot_ac": "P31938", "gene_name": "Map2k1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31938" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P31938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31938" } ] } ] }, { "uniprot_ac": "P32328", "gene_name": "DBF20", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32328" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32328" } ] } ] }, { "uniprot_ac": "P32350", "gene_name": "KNS1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32350" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P32350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32350" } ] } ] }, { "uniprot_ac": "P32361", "gene_name": "IRE1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32361" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "P32361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32361" } ] } ] }, { "uniprot_ac": "P32485", "gene_name": "HOG1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32485" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P32485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32485" } ] } ] }, { "uniprot_ac": "P32490", "gene_name": "MKK1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32490" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P32490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32490" } ] } ] }, { "uniprot_ac": "P32491", "gene_name": "MKK2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32491" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P32491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32491" } ] } ] }, { "uniprot_ac": "P32562", "gene_name": "CDC5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32562" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P32562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32562" } ] } ] }, { "uniprot_ac": "P32581", "gene_name": "IME2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32581" } ] } ] }, { "uniprot_ac": "P32600", "gene_name": "TOR2", "activity": [ { "ec_number": "2.7.1.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.1.67", "activity": "", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] } ] }, { "uniprot_ac": "P32789", "gene_name": "ALK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32789", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32789" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32789", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32789" } ] } ] }, { "uniprot_ac": "P32801", "gene_name": "ELM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32801" } ] } ] }, { "uniprot_ac": "P32944", "gene_name": "SWE1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32944" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32944" } ] } ] }, { "uniprot_ac": "P33076", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] } ] }, { "uniprot_ac": "P33981", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P33981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33981" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P33981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33981" } ] } ] }, { "uniprot_ac": "P34099", "gene_name": "pkaC", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34099" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P34099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34099" } ] } ] }, { "uniprot_ac": "P34100", "gene_name": "pkaD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34100" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34100" } ] } ] }, { "uniprot_ac": "P34101", "gene_name": "fhkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34101" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34101" } ] } ] }, { "uniprot_ac": "P34102", "gene_name": "pkgC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34102" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34102" } ] } ] }, { "uniprot_ac": "P34103", "gene_name": "pkgD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34103" } ] } ] }, { "uniprot_ac": "P34112", "gene_name": "cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] } ] }, { "uniprot_ac": "P34117", "gene_name": "cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34117" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P34117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34117" } ] } ] }, { "uniprot_ac": "P34244", "gene_name": "HSL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34244" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34244" } ] } ] }, { "uniprot_ac": "P35169", "gene_name": "TOR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35169", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35169" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35169", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35169" } ] } ] }, { "uniprot_ac": "P35426", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35426", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35426" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P35426", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35426" } ] } ] }, { "uniprot_ac": "P35465", "gene_name": "Pak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35465" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35465" } ] } ] }, { "uniprot_ac": "P35761", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35761" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P35761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35761" } ] } ] }, { "uniprot_ac": "P36002", "gene_name": "PTK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36002" } ] } ] }, { "uniprot_ac": "P36003", "gene_name": "NNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36003" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36003" } ] } ] }, { "uniprot_ac": "P36004", "gene_name": "KKQ8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36004" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36004" } ] } ] }, { "uniprot_ac": "P36005", "gene_name": "KDX1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36005" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36005" } ] } ] }, { "uniprot_ac": "P36506", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36506" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P36506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36506" } ] } ] }, { "uniprot_ac": "P36507", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36507" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P36507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36507" } ] } ] }, { "uniprot_ac": "P38070", "gene_name": "YPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38070" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38070" } ] } ] }, { "uniprot_ac": "P38080", "gene_name": "AKL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38080" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38080" } ] } ] }, { "uniprot_ac": "P38110", "gene_name": "TEL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38110" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38110" } ] } ] }, { "uniprot_ac": "P38111", "gene_name": "MEC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38111" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38111" } ] } ] }, { "uniprot_ac": "P38147", "gene_name": "CHK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38147" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38147" } ] } ] }, { "uniprot_ac": "P38615", "gene_name": "RIM11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38615" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38615" } ] } ] }, { "uniprot_ac": "P38622", "gene_name": "RCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38622" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38622" } ] } ] }, { "uniprot_ac": "P38623", "gene_name": "RCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38623" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38623" } ] } ] }, { "uniprot_ac": "P38691", "gene_name": "KSP1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38691" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38691" } ] } ] }, { "uniprot_ac": "P38692", "gene_name": "KIC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38692" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38692" } ] } ] }, { "uniprot_ac": "P38970", "gene_name": "HAL5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38970" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38970" } ] } ] }, { "uniprot_ac": "P38990", "gene_name": "SAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38990" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38990" } ] } ] }, { "uniprot_ac": "P38991", "gene_name": "IPL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38991" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38991" } ] } ] }, { "uniprot_ac": "P39009", "gene_name": "DUN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39009" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P39009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39009" } ] } ] }, { "uniprot_ac": "P39073", "gene_name": "SSN3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] } ] }, { "uniprot_ac": "P39951", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] } ] }, { "uniprot_ac": "P39962", "gene_name": "YCK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P39962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39962" } ] } ] }, { "uniprot_ac": "P40160", "gene_name": "RIO2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40160" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P40160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40160" } ] } ] }, { "uniprot_ac": "P40417", "gene_name": "rl", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40417" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40417" } ] } ] }, { "uniprot_ac": "P40494", "gene_name": "PRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40494" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P40494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40494" } ] } ] }, { "uniprot_ac": "P41279", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] } ] }, { "uniprot_ac": "P41695", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41695" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P41695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41695" } ] } ] }, { "uniprot_ac": "P41743", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41743" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P41743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41743" } ] } ] }, { "uniprot_ac": "P41808", "gene_name": "SMK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41808" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P41808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41808" } ] } ] }, { "uniprot_ac": "P42336", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] } ] }, { "uniprot_ac": "P42337", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] } ] }, { "uniprot_ac": "P42338", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] } ] }, { "uniprot_ac": "P42345", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42345" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P42345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42345" } ] } ] }, { "uniprot_ac": "P42346", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P42346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42346" } ] } ] }, { "uniprot_ac": "P42525", "gene_name": "erkA", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42525" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P42525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42525" } ] } ] }, { "uniprot_ac": "P43565", "gene_name": "RIM15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43565" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43565" } ] } ] }, { "uniprot_ac": "P43568", "gene_name": "CAK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43568" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P43568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43568" } ] } ] }, { "uniprot_ac": "P43633", "gene_name": "ALK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43633" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43633" } ] } ] }, { "uniprot_ac": "P43637", "gene_name": "TOS3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43637" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43637" } ] } ] }, { "uniprot_ac": "P45983", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45983" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P45983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45983" } ] } ] }, { "uniprot_ac": "P45984", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45984" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P45984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45984" } ] } ] }, { "uniprot_ac": "P45985", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45985" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P45985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45985" } ] } ] }, { "uniprot_ac": "P46734", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P46734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46734" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P46734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46734" } ] } ] }, { "uniprot_ac": "P46892", "gene_name": "Cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P46892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46892" } ] } ] }, { "uniprot_ac": "P47042", "gene_name": "IKS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47042" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47042" } ] } ] }, { "uniprot_ac": "P47116", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47116" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47116" } ] } ] }, { "uniprot_ac": "P47196", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47196" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47196" } ] } ] }, { "uniprot_ac": "P47197", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47197" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47197" } ] } ] }, { "uniprot_ac": "P47809", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47809" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P47809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47809" } ] } ] }, { "uniprot_ac": "P47811", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47811" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P47811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47811" } ] } ] }, { "uniprot_ac": "P48562", "gene_name": "CLA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48562" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48562" } ] } ] }, { "uniprot_ac": "P48609", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48609" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48609" } ] } ] }, { "uniprot_ac": "P48729", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48729" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48729" } ] } ] }, { "uniprot_ac": "P48730", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] } ] }, { "uniprot_ac": "P48736", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] } ] }, { "uniprot_ac": "P49025", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49025" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49025" } ] } ] }, { "uniprot_ac": "P49071", "gene_name": "MAPk-Ak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49071" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49071" } ] } ] }, { "uniprot_ac": "P49137", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49137" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49137" } ] } ] }, { "uniprot_ac": "P49138", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49138" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49138" } ] } ] }, { "uniprot_ac": "P49185", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49185" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49185" } ] } ] }, { "uniprot_ac": "P49186", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49186" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49186" } ] } ] }, { "uniprot_ac": "P49187", "gene_name": "Mapk10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49187" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49187" } ] } ] }, { "uniprot_ac": "P49336", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] } ] }, { "uniprot_ac": "P49615", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49615" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49615" } ] } ] }, { "uniprot_ac": "P49657", "gene_name": "mnb", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49657" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49657" } ] } ] }, { "uniprot_ac": "P49674", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49674" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49674" } ] } ] }, { "uniprot_ac": "P49759", "gene_name": "CLK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49759" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49759" } ] } ] }, { "uniprot_ac": "P49760", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49760" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49760" } ] } ] }, { "uniprot_ac": "P49761", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49761" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49761" } ] } ] }, { "uniprot_ac": "P49762", "gene_name": "Doa", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] } ] }, { "uniprot_ac": "P49840", "gene_name": "GSK3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] } ] }, { "uniprot_ac": "P49841", "gene_name": "GSK3B", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] } ] }, { "uniprot_ac": "P50613", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] } ] }, { "uniprot_ac": "P50750", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] } ] }, { "uniprot_ac": "P50873", "gene_name": "MRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50873" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P50873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50873" } ] } ] }, { "uniprot_ac": "P51123", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51123" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51123" } ] } ] }, { "uniprot_ac": "P51617", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51617" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51617" } ] } ] }, { "uniprot_ac": "P51812", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51812", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51812" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51812", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51812" } ] } ] }, { "uniprot_ac": "P51817", "gene_name": "PRKX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51817" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51817" } ] } ] }, { "uniprot_ac": "P51952", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] } ] }, { "uniprot_ac": "P51954", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51954" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51954" } ] } ] }, { "uniprot_ac": "P51955", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51955" } ] } ] }, { "uniprot_ac": "P51956", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51956" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51956" } ] } ] }, { "uniprot_ac": "P51957", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51957" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51957" } ] } ] }, { "uniprot_ac": "P52304", "gene_name": "polo", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52304" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52304" } ] } ] }, { "uniprot_ac": "P52480", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] } ] }, { "uniprot_ac": "P52564", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52564" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P52564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52564" } ] } ] }, { "uniprot_ac": "P53104", "gene_name": "ATG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53104" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53104" } ] } ] }, { "uniprot_ac": "P53233", "gene_name": "FMP48", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53233" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53233" } ] } ] }, { "uniprot_ac": "P53323", "gene_name": "BUD32", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53323" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "P53323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53323" } ] } ] }, { "uniprot_ac": "P53349", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53349" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P53349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53349" } ] } ] }, { "uniprot_ac": "P53350", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53350" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P53350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53350" } ] } ] }, { "uniprot_ac": "P53351", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53351" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P53351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53351" } ] } ] }, { "uniprot_ac": "P53355", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53355" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53355" } ] } ] }, { "uniprot_ac": "P53599", "gene_name": "SSK2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53599" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P53599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53599" } ] } ] }, { "uniprot_ac": "P53667", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53667" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53667" } ] } ] }, { "uniprot_ac": "P53668", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53668", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53668" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53668", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53668" } ] } ] }, { "uniprot_ac": "P53669", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53669", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53669" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53669", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53669" } ] } ] }, { "uniprot_ac": "P53670", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53670" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53670" } ] } ] }, { "uniprot_ac": "P53671", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53671", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53671" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53671", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53671" } ] } ] }, { "uniprot_ac": "P53739", "gene_name": "FPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53739" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53739" } ] } ] }, { "uniprot_ac": "P53778", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53778" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P53778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53778" } ] } ] }, { "uniprot_ac": "P53779", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53779" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P53779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53779" } ] } ] }, { "uniprot_ac": "P53894", "gene_name": "CBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53894", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53894" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53894", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53894" } ] } ] }, { "uniprot_ac": "P53974", "gene_name": "ARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53974" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53974" } ] } ] }, { "uniprot_ac": "P54199", "gene_name": "MPS1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54199" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P54199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54199" } ] } ] }, { "uniprot_ac": "P54265", "gene_name": "Dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54265" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54265" } ] } ] }, { "uniprot_ac": "P54360", "gene_name": "fj", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54360" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54360" } ] } ] }, { "uniprot_ac": "P54367", "gene_name": "CkIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54367" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54367" } ] } ] }, { "uniprot_ac": "P54644", "gene_name": "pkbA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54644" } ] } ] }, { "uniprot_ac": "P54645", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] } ] }, { "uniprot_ac": "P54646", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] } ] }, { "uniprot_ac": "P54685", "gene_name": "cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] } ] }, { "uniprot_ac": "P57058", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57058" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57058" } ] } ] }, { "uniprot_ac": "P57059", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57059" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57059" } ] } ] }, { "uniprot_ac": "P57078", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57078" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57078" } ] } ] }, { "uniprot_ac": "P57760", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] } ] }, { "uniprot_ac": "P58750", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P58750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58750" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P58750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58750" } ] } ] }, { "uniprot_ac": "P58801", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] } ] }, { "uniprot_ac": "P59241", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P59241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P59241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59241" } ] } ] }, { "uniprot_ac": "P59895", "gene_name": "Nek6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P59895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59895" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "P59895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59895" } ] } ] }, { "uniprot_ac": "P61088", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61088" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61088" } ] } ] }, { "uniprot_ac": "P61586", "gene_name": "RHOA", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P61586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61586" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P61586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61586" } ] } ] }, { "uniprot_ac": "P63000", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P63000", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63000" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P63000", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63000" } ] } ] }, { "uniprot_ac": "P63085", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63085" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P63085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63085" } ] } ] }, { "uniprot_ac": "P63086", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63086" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P63086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63086" } ] } ] }, { "uniprot_ac": "P63318", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63318" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P63318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63318" } ] } ] }, { "uniprot_ac": "P63319", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63319" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P63319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63319" } ] } ] }, { "uniprot_ac": "P67999", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P67999", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67999" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67999", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67999" } ] } ] }, { "uniprot_ac": "P68181", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68181" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68181" } ] } ] }, { "uniprot_ac": "P68182", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68182" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68182" } ] } ] }, { "uniprot_ac": "P68400", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68400" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68400" } ] } ] }, { "uniprot_ac": "P68403", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68403" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P68403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68403" } ] } ] }, { "uniprot_ac": "P68404", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68404", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68404" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P68404", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68404" } ] } ] }, { "uniprot_ac": "P70218", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70218" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70218" } ] } ] }, { "uniprot_ac": "P70236", "gene_name": "Map2k6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70236" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P70236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70236" } ] } ] }, { "uniprot_ac": "P70268", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70268" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P70268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70268" } ] } ] }, { "uniprot_ac": "P70335", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70335" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70335" } ] } ] }, { "uniprot_ac": "P70336", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70336" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70336" } ] } ] }, { "uniprot_ac": "P70618", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P70618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70618" } ] } ] }, { "uniprot_ac": "P78362", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78362" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78362" } ] } ] }, { "uniprot_ac": "P78368", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78368" } ] } ] }, { "uniprot_ac": "P78527", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78527" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78527" } ] } ] }, { "uniprot_ac": "P79621", "gene_name": "Ciita", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] } ] }, { "uniprot_ac": "P80192", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P80192", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80192" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P80192", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80192" } ] } ] }, { "uniprot_ac": "P83098", "gene_name": "Stlk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83098" } ] } ] }, { "uniprot_ac": "P83099", "gene_name": "Pkcdelta", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] } ] }, { "uniprot_ac": "P83100", "gene_name": "p38c", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83100" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83100" } ] } ] }, { "uniprot_ac": "P83102", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83102" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83102" } ] } ] }, { "uniprot_ac": "P83103", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83103" } ] } ] }, { "uniprot_ac": "P83104", "gene_name": "Takl1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83104" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83104" } ] } ] }, { "uniprot_ac": "P83510", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83510" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83510" } ] } ] }, { "uniprot_ac": "P83741", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83741" } ] } ] }, { "uniprot_ac": "P92208", "gene_name": "bsk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P92208" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P92208" } ] } ] }, { "uniprot_ac": "P97313", "gene_name": "Prkdc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97313" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97313" } ] } ] }, { "uniprot_ac": "P97343", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97343" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97343" } ] } ] }, { "uniprot_ac": "P97377", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97377", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97377" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P97377", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97377" } ] } ] }, { "uniprot_ac": "P97477", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97477", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97477" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97477", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97477" } ] } ] }, { "uniprot_ac": "P97633", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97633" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97633" } ] } ] }, { "uniprot_ac": "P97756", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] } ] }, { "uniprot_ac": "P97820", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97820", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97820" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97820", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97820" } ] } ] }, { "uniprot_ac": "P97874", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97874" } ] } ] }, { "uniprot_ac": "P97924", "gene_name": "Kalrn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97924" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97924" } ] } ] }, { "uniprot_ac": "Q00168", "gene_name": "CaMKII", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00168" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00168" } ] } ] }, { "uniprot_ac": "Q00526", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00526" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00526" } ] } ] }, { "uniprot_ac": "Q00532", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00532" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00532" } ] } ] }, { "uniprot_ac": "Q00534", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00534" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00534" } ] } ] }, { "uniprot_ac": "Q00535", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00535" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q00535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00535" } ] } ] }, { "uniprot_ac": "Q00536", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00536" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00536" } ] } ] }, { "uniprot_ac": "Q00537", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00537" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00537" } ] } ] }, { "uniprot_ac": "Q00772", "gene_name": "SLT2", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00772" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q00772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00772" } ] } ] }, { "uniprot_ac": "Q00972", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] } ] }, { "uniprot_ac": "Q01389", "gene_name": "BCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01389" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01389" } ] } ] }, { "uniprot_ac": "Q01919", "gene_name": "KIN4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01919" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01919" } ] } ] }, { "uniprot_ac": "Q01986", "gene_name": "Map2k1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01986" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q01986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01986" } ] } ] }, { "uniprot_ac": "Q02111", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02111" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02111" } ] } ] }, { "uniprot_ac": "Q02156", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02156" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02156" } ] } ] }, { "uniprot_ac": "Q02720", "gene_name": "casK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02720" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02720" } ] } ] }, { "uniprot_ac": "Q02750", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02750" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q02750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02750" } ] } ] }, { "uniprot_ac": "Q02779", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02779" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q02779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02779" } ] } ] }, { "uniprot_ac": "Q02956", "gene_name": "Prkcz", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02956" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02956" } ] } ] }, { "uniprot_ac": "Q03002", "gene_name": "FRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03002" } ] } ] }, { "uniprot_ac": "Q03042", "gene_name": "Pkg21D", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03042" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03042" } ] } ] }, { "uniprot_ac": "Q03043", "gene_name": "for", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03043" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03043" } ] } ] }, { "uniprot_ac": "Q03114", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03114", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03114" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03114", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03114" } ] } ] }, { "uniprot_ac": "Q03141", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03141" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03141" } ] } ] }, { "uniprot_ac": "Q03147", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] } ] }, { "uniprot_ac": "Q03306", "gene_name": "PKH3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03306" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03306" } ] } ] }, { "uniprot_ac": "Q03407", "gene_name": "PKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03407" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03407" } ] } ] }, { "uniprot_ac": "Q03497", "gene_name": "STE20", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03497" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03497" } ] } ] }, { "uniprot_ac": "Q03533", "gene_name": "TDA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03533" } ] } ] }, { "uniprot_ac": "Q03656", "gene_name": "SKY1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03656" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03656" } ] } ] }, { "uniprot_ac": "Q03785", "gene_name": "VHS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03785" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03785" } ] } ] }, { "uniprot_ac": "Q03963", "gene_name": "Eif2ak2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] } ] }, { "uniprot_ac": "Q04735", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04735" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q04735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04735" } ] } ] }, { "uniprot_ac": "Q04759", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04759" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q04759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04759" } ] } ] }, { "uniprot_ac": "Q04859", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04859", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04859" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04859", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04859" } ] } ] }, { "uniprot_ac": "Q04899", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04899", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04899" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q04899", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04899" } ] } ] }, { "uniprot_ac": "Q05512", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] } ] }, { "uniprot_ac": "Q05513", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05513" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q05513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05513" } ] } ] }, { "uniprot_ac": "Q05652", "gene_name": "pll", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] } ] }, { "uniprot_ac": "Q05655", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] }, { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] } ] }, { "uniprot_ac": "Q06098", "gene_name": "ISR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06098" } ] } ] }, { "uniprot_ac": "Q06226", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06226" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06226" } ] } ] }, { "uniprot_ac": "Q06486", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] } ] }, { "uniprot_ac": "Q07002", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07002" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q07002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07002" } ] } ] }, { "uniprot_ac": "Q07174", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07174" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q07174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07174" } ] } ] }, { "uniprot_ac": "Q07832", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07832" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q07832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07832" } ] } ] }, { "uniprot_ac": "Q07912", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] } ] }, { "uniprot_ac": "Q08217", "gene_name": "PSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q08217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08217" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08217" } ] } ] }, { "uniprot_ac": "Q08732", "gene_name": "HRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q08732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08732" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08732" } ] } ] }, { "uniprot_ac": "Q09013", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q09013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09013" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q09013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09013" } ] } ] }, { "uniprot_ac": "Q09137", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] } ] }, { "uniprot_ac": "Q0KHQ5", "gene_name": "Tao", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHQ5" } ] } ] }, { "uniprot_ac": "Q0KHT7", "gene_name": "Drak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHT7" } ] } ] }, { "uniprot_ac": "Q0KHV6", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHV6" } ] } ] }, { "uniprot_ac": "Q0KL02", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KL02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KL02" } ] } ] }, { "uniprot_ac": "Q12003", "gene_name": "ENV7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12003" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12003" } ] } ] }, { "uniprot_ac": "Q12100", "gene_name": "RTK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12100" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12100" } ] } ] }, { "uniprot_ac": "Q12152", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12152" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12152" } ] } ] }, { "uniprot_ac": "Q12196", "gene_name": "RIO1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] } ] }, { "uniprot_ac": "Q12222", "gene_name": "YGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12222" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12222" } ] } ] }, { "uniprot_ac": "Q12236", "gene_name": "PKH2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12236" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12236" } ] } ] }, { "uniprot_ac": "Q12263", "gene_name": "GIN4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12263" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12263" } ] } ] }, { "uniprot_ac": "Q12310", "gene_name": "PRR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12310" } ] } ] }, { "uniprot_ac": "Q12469", "gene_name": "SKM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12469" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12469" } ] } ] }, { "uniprot_ac": "Q12505", "gene_name": "SKS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12505" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12505" } ] } ] }, { "uniprot_ac": "Q12851", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12851" } ] } ] }, { "uniprot_ac": "Q12852", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12852" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q12852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12852" } ] } ] }, { "uniprot_ac": "Q13043", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13043" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13043" } ] } ] }, { "uniprot_ac": "Q13131", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] } ] }, { "uniprot_ac": "Q13153", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13153" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13153" } ] } ] }, { "uniprot_ac": "Q13163", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13163" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q13163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13163" } ] } ] }, { "uniprot_ac": "Q13164", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13164" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q13164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13164" } ] } ] }, { "uniprot_ac": "Q13177", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13177" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13177" } ] } ] }, { "uniprot_ac": "Q13188", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13188" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13188" } ] } ] }, { "uniprot_ac": "Q13233", "gene_name": "MAP3K1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] }, { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] } ] }, { "uniprot_ac": "Q13237", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13237" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q13237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13237" } ] } ] }, { "uniprot_ac": "Q13315", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13315" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13315" } ] } ] }, { "uniprot_ac": "Q13418", "gene_name": "ILK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13418" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13418" } ] } ] }, { "uniprot_ac": "Q13464", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13464" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13464" } ] } ] }, { "uniprot_ac": "Q13523", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13523" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13523" } ] } ] }, { "uniprot_ac": "Q13535", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13535" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13535" } ] } ] }, { "uniprot_ac": "Q13546", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13546" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13546" } ] } ] }, { "uniprot_ac": "Q13554", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13554" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13554" } ] } ] }, { "uniprot_ac": "Q13555", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13555" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13555" } ] } ] }, { "uniprot_ac": "Q13557", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13557" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13557" } ] } ] }, { "uniprot_ac": "Q13627", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] } ] }, { "uniprot_ac": "Q13976", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13976" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q13976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13976" } ] } ] }, { "uniprot_ac": "Q14004", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] } ] }, { "uniprot_ac": "Q14012", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14012" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q14012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14012" } ] } ] }, { "uniprot_ac": "Q14296", "gene_name": "FASTK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.8", "activity": "ATP + L-threonyl-[Fas-activated protein] = ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein].", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.8", "activity": "", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] } ] }, { "uniprot_ac": "Q14680", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] } ] }, { "uniprot_ac": "Q14AX6", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] } ] }, { "uniprot_ac": "Q15131", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15131" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q15131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15131" } ] } ] }, { "uniprot_ac": "Q15139", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15139" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q15139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15139" } ] } ] }, { "uniprot_ac": "Q15208", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15208" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15208" } ] } ] }, { "uniprot_ac": "Q15349", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15349" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15349" } ] } ] }, { "uniprot_ac": "Q15418", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15418" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15418" } ] } ] }, { "uniprot_ac": "Q15569", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15569" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q15569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15569" } ] } ] }, { "uniprot_ac": "Q15759", "gene_name": "MAPK11", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15759" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q15759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15759" } ] } ] }, { "uniprot_ac": "Q15772", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15772" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15772" } ] } ] }, { "uniprot_ac": "Q15831", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15831" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15831" } ] } ] }, { "uniprot_ac": "Q16512", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16512" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q16512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16512" } ] } ] }, { "uniprot_ac": "Q16513", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16513" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q16513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16513" } ] } ] }, { "uniprot_ac": "Q16539", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16539" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16539" } ] } ] }, { "uniprot_ac": "Q16566", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16566" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q16566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16566" } ] } ] }, { "uniprot_ac": "Q16584", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16584" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q16584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16584" } ] } ] }, { "uniprot_ac": "Q16644", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q16644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16644" } ] } ] }, { "uniprot_ac": "Q16659", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] } ] }, { "uniprot_ac": "Q16816", "gene_name": "PHKG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] } ] }, { "uniprot_ac": "Q1EG27", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1EG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1EG27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1EG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1EG27" } ] } ] }, { "uniprot_ac": "Q1HKZ5", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1HKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HKZ5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q1HKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HKZ5" } ] } ] }, { "uniprot_ac": "Q1ZXC8", "gene_name": "pXi", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXC8" } ] } ] }, { "uniprot_ac": "Q1ZXD6", "gene_name": "roco5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXD6" } ] } ] }, { "uniprot_ac": "Q1ZXH2", "gene_name": "fhkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXH2" } ] } ] }, { "uniprot_ac": "Q1ZXI5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXI5" } ] } ] }, { "uniprot_ac": "Q1ZXR2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXR2" } ] } ] }, { "uniprot_ac": "Q23915", "gene_name": "kinX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q23915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23915" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q23915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23915" } ] } ] }, { "uniprot_ac": "Q23977", "gene_name": "hep", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23977" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23977" } ] } ] }, { "uniprot_ac": "Q24210", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24210" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24210" } ] } ] }, { "uniprot_ac": "Q24324", "gene_name": "Dsor1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24324" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24324" } ] } ] }, { "uniprot_ac": "Q2M2I8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q2M2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2M2I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2M2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2M2I8" } ] } ] }, { "uniprot_ac": "Q2NL51", "gene_name": "Gsk3a", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] } ] }, { "uniprot_ac": "Q38SD2", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q38SD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q38SD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q38SD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q38SD2" } ] } ] }, { "uniprot_ac": "Q3MJK5", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] 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}, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3TYD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TYD6" } ] } ] }, { "uniprot_ac": "Q3TZA2", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3TZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TZA2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3TZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TZA2" } ] } ] }, { "uniprot_ac": "Q3U1V8", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U1V8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q3U1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U1V8" } ] } ] }, { "uniprot_ac": "Q3U214", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U214" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3U214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U214" } ] } ] }, { "uniprot_ac": "Q3U3Q1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U3Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3U3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U3Q1" } ] } ] }, { "uniprot_ac": "Q3UGM2", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UGM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UGM2" } ] } ] }, { "uniprot_ac": "Q3UH66", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UH66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UH66" } ] } ] }, { "uniprot_ac": "Q3UHC2", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHC2" } ] } ] }, { "uniprot_ac": "Q3UHJ0", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHJ0" } ] } ] }, { "uniprot_ac": "Q3ULB5", "gene_name": "Pak6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3ULB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3ULB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3ULB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3ULB5" } ] } ] }, { "uniprot_ac": "Q3UMM4", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMM4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3UMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMM4" } ] } ] }, { "uniprot_ac": "Q3UMW7", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMW7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMW7" } ] } ] }, { "uniprot_ac": "Q3UT86", "gene_name": "Gm5891", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UT86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UT86" } ] } ] }, { "uniprot_ac": "Q3UTA8", "gene_name": "Gm4567", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UTA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UTA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTA8" } ] } ] }, { "uniprot_ac": "Q3UTQ8", "gene_name": "Cdkl5", "activity": 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"https://www.uniprot.org/uniprot/Q3V016" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3V016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V016" } ] } ] }, { "uniprot_ac": "Q3V129", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V129" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3V129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V129" } ] } ] }, { "uniprot_ac": "Q3V3A1", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V3A1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3V3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V3A1" } ] } ] }, { "uniprot_ac": "Q4FZD7", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4FZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4FZD7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q4FZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4FZD7" } ] } ] }, { "uniprot_ac": "Q4G050", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4G050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G050" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4G050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G050" } ] } ] }, { "uniprot_ac": "Q4KLN3", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KLN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4KLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KLN3" } ] } ] }, { "uniprot_ac": "Q4KM34", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KM34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM34" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q4KM34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM34" } ] } ] }, { "uniprot_ac": "Q4KM47", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM47" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q4KM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM47" } ] } ] }, { "uniprot_ac": "Q4KSH6", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q4KSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH6" } ] } ] }, { "uniprot_ac": "Q4KSH7", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KSH7", "database": "UniProtKB", "url": 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"Q54B33", "gene_name": "pakE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54B33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54B33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B33" } ] } ] }, { "uniprot_ac": "Q54B48", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54B48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B48" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54B48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B48" } ] } ] }, { "uniprot_ac": "Q54BC9", "gene_name": "dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54BC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BC9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q54BC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BC9" } ] } ] }, { "uniprot_ac": "Q54BF0", "gene_name": "fhkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54BF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54BF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BF0" } ] } ] }, { "uniprot_ac": "Q54C18", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54C18", "database": "UniProtKB", "url": 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"Q54C71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C71" } ] } ] }, { "uniprot_ac": "Q54D75", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54D75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54D75" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q54D75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54D75" } ] } ] }, { "uniprot_ac": "Q54DC8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DC8" } ] } ] }, { "uniprot_ac": "Q54DF2", "gene_name": "mrkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DF2" } ] } ] }, { "uniprot_ac": "Q54DK3", "gene_name": "cdc7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DK3" } ] } ] }, { "uniprot_ac": "Q54DY0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + 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"https://www.uniprot.org/uniprot/Q54EG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54EG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EG9" } ] } ] }, { "uniprot_ac": "Q54EM1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54EM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54EM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EM1" } ] } ] }, { "uniprot_ac": "Q54ER4", "gene_name": "atr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54ER4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ER4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54ER4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ER4" } ] } ] }, { "uniprot_ac": "Q54ET3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54ET3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ET3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54ET3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ET3" } ] } ] }, { "uniprot_ac": "Q54EY4", "gene_name": "dst3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54EY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54EY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EY4" } ] } ] }, { "uniprot_ac": "Q54F40", 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"Q54HD2", "gene_name": "ndrD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54HD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54HD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HD2" } ] } ] }, { "uniprot_ac": "Q54HS0", "gene_name": "nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54HS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54HS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HS0" } ] } ] }, { "uniprot_ac": "Q54I36", "gene_name": "pyk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + 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"Q54M77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54M77" } ] } ] }, { "uniprot_ac": "Q54MH0", "gene_name": "fhkD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54MH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54MH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MH0" } ] } ] }, { "uniprot_ac": "Q54MV2", "gene_name": "mrkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54MV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54MV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MV2" } ] } ] }, { "uniprot_ac": 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+ H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54P47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54P47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P47" } ] } ] }, { "uniprot_ac": "Q54PK8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK8" } ] } ] }, { "uniprot_ac": "Q54PK9", "gene_name": "pdkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK9" } ] } ] }, { "uniprot_ac": "Q54PX0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PX0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PX0" } ] } ] }, { "uniprot_ac": "Q54Q69", "gene_name": "dhkG", "activity": [ { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "Q54Q69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Q69" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54Q69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Q69" } ] } ] }, { "uniprot_ac": "Q54QB1", "gene_name": "erkB", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QB1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q54QB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QB1" } ] } ] }, { "uniprot_ac": "Q54QD5", "gene_name": "nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QD5" } ] } ] }, { "uniprot_ac": "Q54QI2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QI2" } ] } ] }, { "uniprot_ac": "Q54QQ1", "gene_name": "phg2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QQ1" } ] } ] }, { "uniprot_ac": "Q54QV3", "gene_name": "yakA", "activity": [ { 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"evidence": [ { "id": "Q54R95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54R95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R95" } ] } ] }, { "uniprot_ac": "Q54R98", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54R98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54R98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R98" } ] } ] }, { "uniprot_ac": "Q54RB2", "gene_name": "cdk11", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RB2" } ] }, { 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"https://www.uniprot.org/uniprot/Q54RJ4" } ] } ] }, { "uniprot_ac": "Q54RP7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RP7" } ] } ] }, { "uniprot_ac": "Q54RR9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RR9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RR9" } ] } ] }, { "uniprot_ac": "Q54RV3", "gene_name": "pakG", "activity": [ { 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"Q55GE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GE6" } ] } ] }, { "uniprot_ac": "Q55GG4", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GG4" } ] } ] }, { "uniprot_ac": "Q55GJ2", "gene_name": "ireA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GJ2" } ] } ] }, { "uniprot_ac": "Q55GS4", "gene_name": "cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GS4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q55GS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GS4" } ] } ] }, { "uniprot_ac": "Q55GU0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GU0" } ] } ] }, { "uniprot_ac": "Q55GV3", "gene_name": "pakC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GV3" } ] } ] }, { "uniprot_ac": "Q56UN5", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] } ] }, { "uniprot_ac": "Q59H18", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q59H18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q59H18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q59H18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q59H18" } ] } ] }, { "uniprot_ac": "Q5EAK6", "gene_name": "tefu", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EAK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EAK6" } ] } ] }, { "uniprot_ac": "Q5EG47", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] } ] }, { "uniprot_ac": "Q5F2E8", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5F2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F2E8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F2E8" } ] } ] }, { "uniprot_ac": "Q5GIG6", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5GIG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5GIG6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5GIG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5GIG6" } ] } ] }, { "uniprot_ac": "Q5MAI5", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MAI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MAI5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5MAI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MAI5" } ] } ] }, { "uniprot_ac": "Q5MJS3", "gene_name": "Fam20c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MJS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5MJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MJS3" } ] } ] }, { "uniprot_ac": "Q5MPA9", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MPA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MPA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5MPA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MPA9" } ] } ] }, { "uniprot_ac": "Q5PQT0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5PQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5PQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT0" } ] } ] }, { "uniprot_ac": "Q5RJI5", "gene_name": "Brsk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] } ] }, { "uniprot_ac": "Q5RKH1", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5RKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKH1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5RKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKH1" } ] } ] }, { "uniprot_ac": "Q5S006", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S006" } ] }, { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S006" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S006" } ] } ] }, { "uniprot_ac": "Q5S007", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5S007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S007" } ] }, { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5S007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S007" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5S007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S007" } ] } ] }, { "uniprot_ac": "Q5SUV5", "gene_name": "Mylk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5SUV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SUV5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SUV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SUV5" } ] } ] }, { "uniprot_ac": "Q5SYL1", "gene_name": "Rskr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5SYL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SYL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SYL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SYL1" } ] } ] }, { "uniprot_ac": "Q5TCX8", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5TCX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCX8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q5TCX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCX8" } ] } ] }, { "uniprot_ac": "Q5TCY1", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5TCY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5TCY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCY1" } ] } ] }, { "uniprot_ac": "Q5U2N4", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U2N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U2N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2N4" } ] } ] }, { "uniprot_ac": "Q5U2X5", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] } ] }, { "uniprot_ac": "Q5U452", "gene_name": "Trp53rka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U452" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U452" } ] } ] }, { "uniprot_ac": "Q5U4C9", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U4C9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5U4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U4C9" } ] } ] }, { "uniprot_ac": "Q5VJL3", "gene_name": "gdt9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VJL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VJL3" } ] } ] }, { "uniprot_ac": "Q5VST9", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VST9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VST9" } ] } ] }, { "uniprot_ac": "Q5VT25", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VT25" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VT25" } ] } ] }, { "uniprot_ac": "Q5XIS9", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q5XIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS9" } ] } ] }, { "uniprot_ac": "Q5XIT0", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIT0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIT0" } ] } ] }, { "uniprot_ac": "Q5XJV6", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5XJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XJV6" } ] } ] }, { "uniprot_ac": "Q60592", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60592" } ] } ] }, { "uniprot_ac": "Q60670", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60670" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60670" } ] } ] }, { "uniprot_ac": "Q60700", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60700" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q60700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60700" } ] } ] }, { "uniprot_ac": "Q60737", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60737" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60737" } ] } ] }, { "uniprot_ac": "Q60806", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60806" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q60806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60806" } ] } ] }, { "uniprot_ac": "Q60823", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60823" } ] } ] }, { "uniprot_ac": "Q60855", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60855" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60855" } ] } ] }, { "uniprot_ac": "Q61036", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61036", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61036" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61036", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61036" } ] } ] }, { "uniprot_ac": "Q61083", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61083" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q61083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61083" } ] } ] }, { "uniprot_ac": "Q61084", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61084" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q61084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61084" } ] } ] }, { "uniprot_ac": "Q61097", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61097" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61097" } ] } ] }, { "uniprot_ac": "Q61136", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] } ] }, { "uniprot_ac": "Q61161", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61161" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61161" } ] } ] }, { "uniprot_ac": "Q61214", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] } ] }, { "uniprot_ac": "Q61241", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61241" } ] } ] }, { "uniprot_ac": "Q61410", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61410" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q61410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61410" } ] } ] }, { "uniprot_ac": "Q61532", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61532" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q61532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61532" } ] } ] }, { "uniprot_ac": "Q61831", "gene_name": "Mapk10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61831" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q61831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61831" } ] } ] }, { "uniprot_ac": "Q61846", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] } ] }, { "uniprot_ac": "Q62070", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62070" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62070" } ] } ] }, { "uniprot_ac": "Q62073", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62073" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q62073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62073" } ] } ] }, { "uniprot_ac": "Q62074", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62074" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q62074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62074" } ] } ] }, { "uniprot_ac": "Q62101", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62101" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q62101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62101" } ] } ] }, { "uniprot_ac": "Q62388", "gene_name": "Atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62388" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62388" } ] } ] }, { "uniprot_ac": "Q62406", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62406" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62406" } ] } ] }, { "uniprot_ac": "Q62407", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62407" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62407" } ] } ] }, { "uniprot_ac": "Q62673", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62673" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q62673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62673" } ] } ] }, { "uniprot_ac": "Q62726", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62726" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62726" } ] } ] }, { "uniprot_ac": "Q62761", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62761" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62761" } ] } ] }, { "uniprot_ac": "Q62762", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62762" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62762" } ] } ] }, { "uniprot_ac": "Q62763", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62763" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62763" } ] } ] }, { "uniprot_ac": "Q62829", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62829" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62829" } ] } ] }, { "uniprot_ac": "Q62862", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62862" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q62862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62862" } ] } ] }, { "uniprot_ac": "Q62868", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62868" } ] } ] }, { "uniprot_ac": "Q62915", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62915" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62915" } ] } ] }, { "uniprot_ac": "Q62925", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62925", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62925" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q62925", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62925" } ] } ] }, { "uniprot_ac": "Q63117", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63117" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63117" } ] } ] }, { "uniprot_ac": "Q63184", "gene_name": "Eif2ak2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] } ] }, { "uniprot_ac": "Q63185", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63185" } ] } ] }, { "uniprot_ac": "Q63285", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63285" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63285" } ] } ] }, { "uniprot_ac": "Q63433", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63433" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q63433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63433" } ] } ] }, { "uniprot_ac": "Q63450", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63450" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q63450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63450" } ] } ] }, { "uniprot_ac": "Q63454", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63454" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63454" } ] } ] }, { 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"https://www.uniprot.org/uniprot/Q63538" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63538" } ] } ] }, { "uniprot_ac": "Q63553", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63553" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63553" } ] } ] }, { "uniprot_ac": "Q63562", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63562" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q63562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63562" } ] } ] }, { "uniprot_ac": "Q63572", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63572" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63572" } ] } ] }, { "uniprot_ac": "Q63638", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63638" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63638" } ] } ] }, { "uniprot_ac": "Q63644", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63644" } ] } ] }, { "uniprot_ac": "Q63686", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63686" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q63686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63686" } ] } ] }, { "uniprot_ac": "Q63699", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63699" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q63699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63699" } ] } ] }, { "uniprot_ac": "Q63796", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63796" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q63796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63796" } ] } ] }, { "uniprot_ac": "Q63844", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63844", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q64303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64303" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q64303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64303" } ] } ] }, { "uniprot_ac": "Q64595", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64595" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q64595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64595" } ] } ] }, { "uniprot_ac": "Q64617", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64617" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q64617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64617" } ] } ] }, { "uniprot_ac": "Q64702", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] } ] }, { "uniprot_ac": "Q66H84", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66H84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q66H84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H84" } ] } ] }, { "uniprot_ac": "Q66HA1", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HA1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q66HA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HA1" } ] } ] }, { "uniprot_ac": "Q66HE5", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q66HE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE5" } ] } ] }, { "uniprot_ac": "Q66HE7", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q66HE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE7" } ] } ] }, { "uniprot_ac": "Q66L42", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66L42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66L42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q66L42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66L42" } ] } ] }, { "uniprot_ac": "Q69Z98", "gene_name": "Brsk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] } ] }, { "uniprot_ac": "Q69ZA1", "gene_name": "Cdk13", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] } ] }, { "uniprot_ac": "Q69ZM6", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69ZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q69ZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZM6" } ] } ] }, { "uniprot_ac": "Q6A1A2", "gene_name": "PDPK2P", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6A1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6A1A2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6A1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6A1A2" } ] } ] }, { "uniprot_ac": "Q6B9X6", "gene_name": "vwkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6B9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B9X6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6B9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B9X6" } ] } ] }, { "uniprot_ac": "Q6DT37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6DT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DT37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6DT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DT37" } ] } ] }, { "uniprot_ac": "Q6IQ55", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6IQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6IQ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6IQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6IQ55" } ] } ] }, { "uniprot_ac": "Q6P0Q8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P0Q8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P0Q8" } ] } ] }, { "uniprot_ac": "Q6P2M8", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P2M8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q6P2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P2M8" } ] } ] }, { "uniprot_ac": "Q6P3R8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P3R8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P3R8" } ] } ] }, { "uniprot_ac": "Q6P4S6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4S6" } ] } ] }, { "uniprot_ac": "Q6P5G0", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5G0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q6P5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5G0" } ] } ] }, { "uniprot_ac": "Q6P5Z2", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P5Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5Z2" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q6P5Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5Z2" } ] } ] }, { "uniprot_ac": "Q6P9R2", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9R2" } ] } ] }, { "uniprot_ac": "Q6PAJ1", "gene_name": "Bcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PAJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PAJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PAJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PAJ1" } ] } ] }, { "uniprot_ac": "Q6PCN3", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PCN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PCN3" } ] } ] }, { "uniprot_ac": "Q6PGN3", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PGN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PGN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PGN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PGN3" } ] } ] }, { "uniprot_ac": "Q6PHR2", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PHR2", "database": "UniProtKB", "url": 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[ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9V9" } ] } ] }, { "uniprot_ac": "Q6V9Y2", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y2" } ] } ] }, { "uniprot_ac": "Q6V9Y3", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", 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"evidence": [ { "id": "Q6ZN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZN16" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q6ZN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZN16" } ] } ] }, { "uniprot_ac": "Q6ZQ29", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZQ29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZQ29" } ] } ] }, { "uniprot_ac": "Q6ZWH5", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZWH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZWH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZWH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZWH5" } ] } ] }, { "uniprot_ac": "Q70PP2", "gene_name": "nonC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q70PP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q70PP2" } ] } ] }, { "uniprot_ac": "Q75JK0", "gene_name": "zakA", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q75JK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JK0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q75JK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JK0" } ] } ] }, { "uniprot_ac": "Q75JN1", "gene_name": "ifkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q75JN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q75JN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JN1" } ] } ] }, { "uniprot_ac": "Q76MJ5", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] } ] }, { "uniprot_ac": "Q76NV1", "gene_name": "dyrk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76NV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76NV1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q76NV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76NV1" } ] } ] }, { "uniprot_ac": "Q76P07", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76P07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76P07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q76P07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76P07" } ] } ] }, { "uniprot_ac": "Q7KRY6", "gene_name": "ball", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KRY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KRY6" } ] } ] }, { "uniprot_ac": "Q7KZI7", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] } ] }, { "uniprot_ac": "Q7L7X3", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7L7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L7X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7L7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L7X3" } ] } ] }, { "uniprot_ac": "Q7PLI7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7PLI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7PLI7" } ] } ] }, { "uniprot_ac": "Q7TNJ7", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNJ7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q7TNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNJ7" } ] } ] }, { "uniprot_ac": "Q7TNL3", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL3" } ] } ] }, { "uniprot_ac": "Q7TNL4", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL4" } ] } ] }, { "uniprot_ac": "Q7TPK6", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TPK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TPK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPK6" } ] } ] }, { "uniprot_ac": "Q7TPS0", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPS0" } ] } ] }, { "uniprot_ac": "Q7TQP6", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TQP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TQP6" } ] } ] }, { "uniprot_ac": "Q7TSC3", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSC3" } ] } ] }, { "uniprot_ac": "Q7TSE6", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSE6" } ] } ] }, { "uniprot_ac": "Q7TSJ6", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSJ6" } ] } ] }, { "uniprot_ac": "Q7TT49", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT49" } ] } ] }, { "uniprot_ac": "Q7TT50", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TT50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT50" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TT50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT50" } ] } ] }, { "uniprot_ac": "Q7Z2Y5", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7Z2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7Z2Y5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7Z2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7Z2Y5" } ] } ] }, { "uniprot_ac": "Q80TR8", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80TR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TR8" } ] } ] }, { "uniprot_ac": "Q80UE6", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UE6" } ] } ] }, { "uniprot_ac": "Q80UV9", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] } ] }, { "uniprot_ac": "Q80UW5", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UW5" } ] } ] }, { "uniprot_ac": "Q80X41", "gene_name": "Vrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80X41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80X41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80X41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80X41" } ] } ] }, { "uniprot_ac": "Q80XI6", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80XI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XI6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q80XI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XI6" } ] } ] }, { "uniprot_ac": "Q80XP9", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80XP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80XP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XP9" } ] } ] }, { "uniprot_ac": "Q80Y86", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Y86" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q80Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Y86" } ] } ] }, { "uniprot_ac": "Q80YE4", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80YE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE4" } ] } ] }, { "uniprot_ac": "Q80YE7", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YE7", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q869L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869L4" } ] } ] }, { "uniprot_ac": "Q869N2", "gene_name": "pakB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869N2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869N2" } ] } ] }, { "uniprot_ac": "Q869T7", "gene_name": "pakF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869T7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869T7" } ] } ] }, { "uniprot_ac": "Q869X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869X3" } ] } ] }, { "uniprot_ac": "Q86A12", "gene_name": "sky1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86A12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86A12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86A12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86A12" } ] } ] }, { "uniprot_ac": "Q86AE1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86AE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86AE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AE1" } ] } ] }, { "uniprot_ac": "Q86AT8", "gene_name": "spkA-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86AT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86AT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AT8" } ] } ] }, { "uniprot_ac": "Q86C65", "gene_name": "tor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86C65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86C65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86C65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86C65" } ] } ] }, { "uniprot_ac": "Q86CS2", "gene_name": "atg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86CS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86CS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86CS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86CS2" } ] } ] }, { "uniprot_ac": "Q86HG9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HG9" } ] } ] }, { "uniprot_ac": "Q86HN7", "gene_name": "PLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HN7" } ] } ] }, { "uniprot_ac": "Q86HW6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HW6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HW6" } ] } ] }, { "uniprot_ac": "Q86I06", "gene_name": "nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86I06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86I06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86I06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86I06" } ] } ] }, { "uniprot_ac": "Q86IX1", "gene_name": "dst1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86IX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86IX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IX1" } ] } ] }, { "uniprot_ac": "Q86SG6", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86SG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86SG6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86SG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86SG6" } ] } ] }, { "uniprot_ac": "Q86TB3", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86TB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86TB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86TB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86TB3" } ] } ] }, { "uniprot_ac": "Q86UE8", "gene_name": "TLK2", "activity": [ { 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"evidence": [ { "id": "Q86V86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86V86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V86" } ] } ] }, { "uniprot_ac": "Q86Y07", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86Y07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Y07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86Y07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Y07" } ] } ] }, { "uniprot_ac": "Q86YV6", "gene_name": "MYLK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86YV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86YV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86YV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86YV6" } ] } ] }, { "uniprot_ac": "Q86Z02", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86Z02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Z02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86Z02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Z02" } ] } ] }, { "uniprot_ac": "Q8BG48", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG48" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BG48", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q8BKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BKX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BKX6" } ] } ] }, { "uniprot_ac": "Q8BLF2", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BLF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLF2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8BLF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLF2" } ] } ] }, { "uniprot_ac": "Q8BLK9", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BLK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLK9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BLK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLK9" } ] } ] }, { "uniprot_ac": "Q8BN21", "gene_name": "Vrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BN21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BN21" } ] } ] }, { "uniprot_ac": "Q8BPM2", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BPM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BPM2" } ] } ] }, { "uniprot_ac": "Q8BRK8", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] } ] }, { "uniprot_ac": "Q8BSK8", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BSK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BSK8" } ] } ] }, { "uniprot_ac": "Q8BTH8", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTH8" } ] } ] }, { "uniprot_ac": "Q8BTI9", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] } ] }, { "uniprot_ac": "Q8BTW9", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTW9" } ] } ] }, { "uniprot_ac": "Q8BVP5", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BVP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BVP5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BVP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BVP5" } ] } ] }, { "uniprot_ac": "Q8BW96", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BW96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BW96" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8BW96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BW96" } ] } ] }, { "uniprot_ac": "Q8BWD8", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWD8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8BWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWD8" } ] } ] }, { "uniprot_ac": "Q8BWE1", "gene_name": "1810024B03Rik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWE1" } ] } ] }, { "uniprot_ac": "Q8BWQ5", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BWQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWQ5" } ] } ] }, { "uniprot_ac": "Q8BWW9", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWW9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8BWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWW9" } ] } ] }, { "uniprot_ac": "Q8BYC6", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYC6" } ] } ] }, { "uniprot_ac": "Q8BYR2", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYR2" } ] } ] }, { "uniprot_ac": "Q8BZ03", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ03" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ03" } ] } ] }, { "uniprot_ac": "Q8BZ25", "gene_name": "Ankk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ25" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ25" } ] } ] }, { "uniprot_ac": "Q8BZN4", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BZN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZN4" } ] } ] }, { "uniprot_ac": "Q8C015", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C015", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C015" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C015", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C015" } ] } ] }, { "uniprot_ac": "Q8C050", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C050" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C050" } ] } ] }, { "uniprot_ac": "Q8C078", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C078" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8C078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C078" } ] } ] }, { "uniprot_ac": "Q8C0N0", "gene_name": "Gm4922", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0N0" } ] } ] }, { "uniprot_ac": "Q8C0P0", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0P0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0P0" } ] } ] }, { "uniprot_ac": "Q8C0Q4", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0Q4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0Q4" } ] } ] }, { "uniprot_ac": "Q8C0V0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V0" } ] } ] }, { "uniprot_ac": "Q8C0V7", "gene_name": "Stk-ps2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V7" } ] } ] }, { "uniprot_ac": "Q8C0X8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0X8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0X8" } ] } ] }, { "uniprot_ac": "Q8C1R0", "gene_name": "Tssk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C1R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C1R0" } ] } ] }, { "uniprot_ac": "Q8C4X2", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C4X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C4X2" } ] } ] }, { "uniprot_ac": "Q8CDB0", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CDB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CDB0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CDB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CDB0" } ] } ] }, { "uniprot_ac": "Q8CE90", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CE90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE90" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q8CE90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE90" } ] } ] }, { "uniprot_ac": "Q8CEE6", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CEE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CEE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEE6" } ] } ] }, { "uniprot_ac": "Q8CEQ0", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEQ0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8CEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEQ0" } ] } ] }, { "uniprot_ac": "Q8CFH6", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFH6" } ] } ] }, { "uniprot_ac": "Q8CIN4", "gene_name": "Pak2", "activity": [ 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"Q8NFD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NFD2" } ] } ] }, { "uniprot_ac": "Q8NG66", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NG66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NG66" } ] } ] }, { "uniprot_ac": "Q8QZR7", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZR7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZR7" } ] } ] }, { "uniprot_ac": "Q8QZV4", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZV4" } ] } ] }, { "uniprot_ac": "Q8QZX0", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZX0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZX0" } ] } ] }, { "uniprot_ac": "Q8R2S1", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2S1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2S1" } ] } ] }, { "uniprot_ac": "Q8R3L8", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] } ] }, { "uniprot_ac": "Q8R4K2", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4K2" } ] } ] }, { "uniprot_ac": "Q8R4U9", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4U9" } ] } ] }, { "uniprot_ac": "Q8R4V0", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V0" } ] } ] }, { "uniprot_ac": "Q8SSS9", "gene_name": "qkgA-2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSS9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8SSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSS9" } ] } ] }, { "uniprot_ac": "Q8SSV3", "gene_name": "mkcD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8SSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSV3" } ] } ] }, { "uniprot_ac": "Q8SSY6", "gene_name": "", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q8SSY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSY6" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSY6" } ] } ] }, { "uniprot_ac": "Q8T0S6", "gene_name": "hpo", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T0S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T0S6" } ] } ] }, { "uniprot_ac": "Q8T2I8", "gene_name": "sepA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T2I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T2I8" } ] } ] }, { "uniprot_ac": "Q8T9L5", "gene_name": "Lkb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T9L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T9L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9L5" } ] } ] }, { "uniprot_ac": "Q8TAS1", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TAS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TAS1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TAS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TAS1" } ] } ] }, { "uniprot_ac": "Q8TD08", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD08" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q8TD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD08" } ] } ] }, { "uniprot_ac": "Q8TD19", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD19" } ] } ] }, { "uniprot_ac": "Q8TDC3", "gene_name": "BRSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] } ] }, { "uniprot_ac": "Q8TDR2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDR2" } ] } ] }, { "uniprot_ac": "Q8TDX7", "gene_name": "NEK7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDX7" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q8TDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDX7" } ] } ] }, { "uniprot_ac": "Q8TF76", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TF76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TF76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF76" } ] } ] }, { "uniprot_ac": "Q8VBY2", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VBY2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8VBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VBY2" } ] } ] }, { "uniprot_ac": "Q8VCT9", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VCT9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q8VCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VCT9" } ] } ] }, { "uniprot_ac": "Q8VD65", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD65" } ] } ] }, { "uniprot_ac": "Q8VDF3", "gene_name": "Dapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VDF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDF3" } ] } ] }, { "uniprot_ac": "Q8VDG6", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDG6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q8VDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDG6" } ] } ] }, { "uniprot_ac": "Q8VDU5", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDU5" } ] } ] }, { "uniprot_ac": "Q8VHF0", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VHF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VHF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHF0" } ] } ] }, { "uniprot_ac": "Q8VHJ5", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] } ] }, { "uniprot_ac": "Q8WU08", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WU08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WU08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WU08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WU08" } ] } ] }, { "uniprot_ac": "Q8WXR4", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WXR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WXR4" } ] } ] }, { "uniprot_ac": "Q8WZ42", "gene_name": "TTN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WZ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WZ42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WZ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WZ42" } ] } ] }, { "uniprot_ac": "Q91VB2", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91VB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VB2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q91VB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VB2" } ] } ] }, { "uniprot_ac": "Q91VJ4", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91VJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91VJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VJ4" } ] } ] }, { "uniprot_ac": "Q91XS8", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91XS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91XS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS8" } ] } ] }, { "uniprot_ac": "Q91Y86", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Y86" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q91Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Y86" } ] } ] }, { "uniprot_ac": "Q91YA2", "gene_name": "Pskh1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91YA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91YA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YA2" } ] } ] }, { "uniprot_ac": "Q91YS8", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91YS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YS8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q91YS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YS8" } ] } ] }, { "uniprot_ac": "Q91Z96", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91Z96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91Z96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z96" } ] } ] }, { "uniprot_ac": "Q91ZB0", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZB0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZB0" } ] } ] }, { "uniprot_ac": "Q91ZN7", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.4.99.18", "activity": "a dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = a dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-[protein].", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.4.99.18", "activity": "", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] } ] }, { "uniprot_ac": "Q91ZR4", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZR4" } ] } ] }, { "uniprot_ac": "Q922Q2", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] } ] }, { "uniprot_ac": "Q922R0", "gene_name": "Prkx", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q922R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922R0" } ] } ] }, { "uniprot_ac": "Q922Y0", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Y0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q922Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Y0" } ] } ] }, { "uniprot_ac": "Q923J1", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q923J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923J1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q923J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923J1" } ] } ] }, { "uniprot_ac": "Q923T9", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q923T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923T9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q923T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923T9" } ] } ] }, { "uniprot_ac": "Q924C5", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924C5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924C5" } ] } ] }, { "uniprot_ac": "Q924I2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924I2" } ] } ] }, { "uniprot_ac": "Q924U5", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924U5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q924U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924U5" } ] } ] }, { "uniprot_ac": "Q924X7", "gene_name": "Stk33", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924X7" } ] } ] }, { "uniprot_ac": "Q925B3", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925B3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q925B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925B3" } ] } ] }, { "uniprot_ac": "Q925D6", "gene_name": "Map2k6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925D6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q925D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925D6" } ] } ] }, { "uniprot_ac": "Q925K9", "gene_name": "Tssk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925K9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q925K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925K9" } ] } ] }, { "uniprot_ac": "Q92630", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92630" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q92630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92630" } ] } ] }, { "uniprot_ac": "Q92772", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92772" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q92772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92772" } ] } ] }, { "uniprot_ac": "Q92918", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92918", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92918" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q92918", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92918" } ] } ] }, { "uniprot_ac": "Q94533", "gene_name": "S6k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q94533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q94533" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q94533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q94533" } ] } ] }, { "uniprot_ac": "Q95SH0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95SH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95SH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95SH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95SH0" } ] } ] }, { "uniprot_ac": "Q95TN8", "gene_name": "gwl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95TN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95TN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95TN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95TN8" } ] } ] }, { "uniprot_ac": "Q95UN8", "gene_name": "slpr", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95UN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95UN8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q95UN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95UN8" } ] } ] }, { "uniprot_ac": "Q95YH0", "gene_name": "cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] } ] }, { "uniprot_ac": "Q96BR1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96BR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96BR1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96BR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96BR1" } ] } ] }, { "uniprot_ac": "Q96C45", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96C45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96C45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96C45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96C45" } ] } ] }, { "uniprot_ac": "Q96GD4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96GD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96GD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD4" } ] } ] }, { "uniprot_ac": "Q96GX5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96GX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GX5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96GX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GX5" } ] } ] }, { "uniprot_ac": "Q96J92", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96J92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96J92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96J92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96J92" } ] } ] }, { "uniprot_ac": "Q96KB5", "gene_name": "PBK", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96KB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96KB5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q96KB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96KB5" } ] } ] }, { "uniprot_ac": "Q96L34", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96L34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96L34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L34" } ] } ] }, { "uniprot_ac": "Q96L96", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96L96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96L96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L96" } ] } ] 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ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] } ] }, { "uniprot_ac": "Q9BUB5", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BUB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BUB5" } ] } ] }, { "uniprot_ac": "Q9BVS4", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVS4" } ] } ] }, { "uniprot_ac": "Q9BWU1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BWU1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9BWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BWU1" } ] } ] }, { "uniprot_ac": "Q9BX84", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BX84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BX84" } ] } ] }, { "uniprot_ac": "Q9BXA6", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA6" } ] } ] }, { "uniprot_ac": "Q9BXA7", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA7" } ] } ] }, { "uniprot_ac": "Q9BXM7", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXM7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXM7" } ] } ] }, { "uniprot_ac": "Q9BXU1", "gene_name": "STK31", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXU1" } ] } ] }, { "uniprot_ac": "Q9BYP7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYP7" } ] } ] }, { "uniprot_ac": "Q9BYT3", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYT3" } ] } ] }, { "uniprot_ac": "Q9BZL6", "gene_name": "PRKD2", "activity": [ { 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"evidence": [ { "id": "Q9CQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9CQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQS5" } ] } ] }, { "uniprot_ac": "Q9CXB8", "gene_name": "Alpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9CXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CXB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9CXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CXB8" } ] } ] }, { "uniprot_ac": "Q9D2E1", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9D2E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D2E1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9D2E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D2E1" } ] } ] }, { "uniprot_ac": "Q9D411", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9D411", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D411" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9D411", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D411" } ] } ] }, { "uniprot_ac": "Q9DBU3", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9DBU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9DBU3", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2K8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2K8" } ] } ] }, { "uniprot_ac": "Q9H2X6", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2X6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2X6" } ] } ] }, { "uniprot_ac": "Q9H422", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H422" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H422" } ] } ] }, { "uniprot_ac": "Q9H4A3", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H4A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4A3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H4A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4A3" } ] } ] }, { "uniprot_ac": "Q9H4B4", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4B4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q9H4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4B4" } ] } ] }, { "uniprot_ac": "Q9HAZ1", "gene_name": "CLK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HAZ1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9HAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HAZ1" } ] } ] }, { "uniprot_ac": "Q9HBH9", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBH9" } ] } ] }, { "uniprot_ac": "Q9HBY8", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBY8" } ] } ] }, { "uniprot_ac": "Q9HC98", "gene_name": "NEK6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HC98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HC98" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9HC98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HC98" } ] } ] }, { "uniprot_ac": "Q9HCP0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HCP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HCP0" } ] } ] }, { "uniprot_ac": "Q9JHG7", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] } ] }, { "uniprot_ac": "Q9JHU3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHU3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHU3" } ] } ] }, { "uniprot_ac": "Q9JI10", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JI10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI10" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JI10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI10" } ] } ] }, { "uniprot_ac": "Q9JI11", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JI11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JI11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI11" } ] } ] }, { "uniprot_ac": "Q9JIH7", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JIH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JIH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIH7" } ] } ] }, { "uniprot_ac": "Q9JIX9", "gene_name": "Fastk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.8", "activity": "ATP + L-threonyl-[Fas-activated protein] = ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein].", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.8", "activity": "", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] } ] }, { "uniprot_ac": "Q9JJ78", "gene_name": "Pbk", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJ78" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q9JJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJ78" } ] } ] }, { "uniprot_ac": "Q9JJX8", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJX8" } ] } ] }, { "uniprot_ac": "Q9JKK8", "gene_name": "Atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKK8" } ] } ] }, { "uniprot_ac": "Q9JKV2", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JKV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JKV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKV2" } ] } ] }, { "uniprot_ac": "Q9JLM8", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLM8" } ] } ] }, { "uniprot_ac": "Q9JLN9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLN9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLN9" } ] } ] }, { "uniprot_ac": "Q9JLS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLS3" } ] } ] }, { "uniprot_ac": "Q9JM01", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM01" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9JM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM01" } ] } ] }, { "uniprot_ac": "Q9JM52", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM52" } ] } ] }, { "uniprot_ac": "Q9JMK2", "gene_name": "Csnk1e", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JMK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JMK2" } ] } ] }, { "uniprot_ac": "Q9NBK5", "gene_name": "trc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NBK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NBK5" } ] } ] }, { "uniprot_ac": "Q9NGW9", "gene_name": "mkcB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NGW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NGW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NGW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NGW9" } ] } ] }, { "uniprot_ac": "Q9NI63", "gene_name": "Myt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NI63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NI63" } ] } ] }, { "uniprot_ac": "Q9NIV1", "gene_name": "PEK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NIV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NIV1" } ] } ] }, { "uniprot_ac": "Q9NQU5", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NQU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NQU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NQU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NQU5" } ] } ] }, { "uniprot_ac": "Q9NR20", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NR20" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9NR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NR20" } ] } ] }, { "uniprot_ac": "Q9NRH2", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRH2" } ] } ] }, { "uniprot_ac": "Q9NRM7", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRM7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRM7" } ] } ] }, { "uniprot_ac": "Q9NRP7", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NRP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NRP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRP7" } ] } ] }, { "uniprot_ac": "Q9NSY1", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NSY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NSY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NSY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NSY1" } ] } ] }, { "uniprot_ac": "Q9NWZ3", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NWZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NWZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NWZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NWZ3" } ] } ] }, { "uniprot_ac": "Q9NY57", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = 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ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UK32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UK32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UK32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UK32" } ] } ] }, { "uniprot_ac": "Q9UKE5", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UKE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UKE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKE5" } ] } ] }, { "uniprot_ac": "Q9UKI8", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UKI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UKI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKI8" } ] } ] }, { "uniprot_ac": "Q9UL54", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UL54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UL54" } ] } ] }, { "uniprot_ac": "Q9UPE1", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPE1" } ] } ] }, { "uniprot_ac": "Q9UPZ9", "gene_name": "CILK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UPZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPZ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UPZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPZ9" } ] } ] }, { "uniprot_ac": "Q9UQ07", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ07" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9UQ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ07" } ] } ] }, { "uniprot_ac": "Q9UQ88", "gene_name": "CDK11A", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ88" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9UQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ88" } ] } ] }, { "uniprot_ac": "Q9UQB9", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQB9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UQB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQB9" } ] } ] }, { "uniprot_ac": "Q9UQM7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQM7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q9UQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQM7" } ] } ] }, { "uniprot_ac": "Q9V3D5", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3D5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3D5" } ] } ] }, { "uniprot_ac": "Q9V3I5", "gene_name": "JIL-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3I5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3I5" } ] } ] }, { "uniprot_ac": "Q9V3Q6", "gene_name": "Tak1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3Q6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3Q6" } ] } ] }, { "uniprot_ac": "Q9VA38", "gene_name": "wts", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VA38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VA38" } ] } ] }, { "uniprot_ac": "Q9VBU2", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VBU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VBU2" } ] } ] }, { "uniprot_ac": "Q9VCV0", "gene_name": "Takl2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VCV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VCV0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9VCV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VCV0" } ] } ] }, { "uniprot_ac": "Q9VD82", "gene_name": "Dmel\\CG6800", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VD82" } ] } ] }, { "uniprot_ac": "Q9VE06", "gene_name": "cdi", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VE06" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VE06" } ] } ] }, { "uniprot_ac": "Q9VEN3", "gene_name": "GckIII", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VEN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VEN3" } ] } ] }, { "uniprot_ac": "Q9VGF9", "gene_name": "aurA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VGF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VGF9" } ] } ] }, { "uniprot_ac": "Q9VI13", "gene_name": "Pak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI13" } ] } ] }, { "uniprot_ac": "Q9VI84", "gene_name": "Dmel\\CG1227", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI84" } ] } ] }, { "uniprot_ac": "Q9VJ30", "gene_name": "Nak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJ30" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJ30" } ] } ] }, { "uniprot_ac": "Q9VJC2", "gene_name": "Dmel\\CG7094", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VJC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJC2" } ] } ] }, { "uniprot_ac": "Q9VK45", "gene_name": "mTor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VK45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VK45" } ] } ] }, { "uniprot_ac": "Q9VKN7", "gene_name": "aurB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VKN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VKN7" } ] } ] }, { "uniprot_ac": "Q9VL34", "gene_name": "Dmel\\CG4839", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VL34" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VL34" } ] } ] }, { "uniprot_ac": "Q9VM90", "gene_name": "meng", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VM90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VM90" } ] } ] }, { "uniprot_ac": "Q9VMY8", "gene_name": "aux", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VMY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VMY8" } ] } ] }, { "uniprot_ac": "Q9VN23", "gene_name": "CG10532", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VN23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VN23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VN23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VN23" } ] } ] }, { "uniprot_ac": "Q9VP22", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] } ] }, { "uniprot_ac": "Q9VPC0", "gene_name": "Pitslre", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VPC0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VPC0" } ] } ] }, { "uniprot_ac": "Q9VR42", "gene_name": "Dmel\\CG3008", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VR42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VR42" } ] } ] }, { "uniprot_ac": "Q9VRJ6", "gene_name": "Tcs5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VRJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VRJ6" } ] } ] }, { "uniprot_ac": "Q9VT57", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] } ] }, { "uniprot_ac": "Q9VTL5", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTL5" } ] } ] }, { "uniprot_ac": "Q9VUQ9", "gene_name": "dop", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUQ9" } ] } ] }, { "uniprot_ac": "Q9VUV4", "gene_name": "sff", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUV4" } ] } ] }, { "uniprot_ac": "Q9VW24", "gene_name": "wnd", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VW24" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VW24" } ] } ] }, { "uniprot_ac": "Q9VXE3", "gene_name": "Rok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE3" } ] } ] }, { "uniprot_ac": "Q9VXE5", "gene_name": "mbt", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE5" } ] } ] }, { "uniprot_ac": "Q9VXG8", "gene_name": "mei-41", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXG8" } ] } ] }, { "uniprot_ac": "Q9VXN5", "gene_name": "Dmel\\CG8565", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXN5" } ] } ] }, { "uniprot_ac": "Q9VZI2", "gene_name": "Ack", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] } ] }, { "uniprot_ac": "Q9W002", "gene_name": "msn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W002" } ] } ] }, { "uniprot_ac": "Q9W0V1", "gene_name": "Pdk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W0V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W0V1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W0V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W0V1" } ] } ] }, { "uniprot_ac": "Q9W1B0", "gene_name": "gek", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W1B0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W1B0" } ] } ] }, { "uniprot_ac": "Q9W354", "gene_name": "Erk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W354" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9W354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W354" } ] } ] }, { "uniprot_ac": "Q9W3N8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W3N8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W3N8" } ] } ] }, { "uniprot_ac": "Q9WTK7", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WTK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTK7" } ] } ] }, { "uniprot_ac": "Q9WTQ0", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9WTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ0" } ] } ] }, { "uniprot_ac": "Q9WTQ1", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9WTQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ1" } ] } ] }, { "uniprot_ac": "Q9WTR2", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTR2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTR2" } ] } ] }, { "uniprot_ac": "Q9WTU6", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTU6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WTU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTU6" } ] } ] }, { "uniprot_ac": "Q9WTY9", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTY9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTY9" } ] } ] }, { "uniprot_ac": "Q9WUA6", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUA6" } ] } ] }, { "uniprot_ac": "Q9WUI1", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUI1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUI1" } ] } ] }, { "uniprot_ac": "Q9WUL6", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUL6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9WUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUL6" } ] } ] }, { "uniprot_ac": "Q9WUN2", "gene_name": "Tbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUN2" } ] } ] }, { "uniprot_ac": "Q9WUT3", "gene_name": "Rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUT3" } ] } ] }, { "uniprot_ac": "Q9WV60", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] } ] }, { "uniprot_ac": "Q9WVC6", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVC6" } ] } ] }, { "uniprot_ac": "Q9WVS4", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9WVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS4" } ] } ] }, { "uniprot_ac": "Q9WVS7", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q9WVS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS7" } ] } ] }, { "uniprot_ac": "Q9WVS8", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS8" } ] } ] }, { "uniprot_ac": "Q9Y243", "gene_name": "AKT3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y243" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y243" } ] } ] }, { "uniprot_ac": "Q9Y2H1", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H1" } ] } ] }, { "uniprot_ac": "Q9Y2H9", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H9" } ] } ] }, { "uniprot_ac": "Q9Y2I7", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] } ] }, { "uniprot_ac": "Q9Y2K2", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2K2" } ] } ] }, { "uniprot_ac": "Q9Y2U5", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2U5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9Y2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2U5" } ] } ] }, { "uniprot_ac": "Q9Y3S1", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y3S1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y3S1" } ] } ] }, { "uniprot_ac": "Q9Y463", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y463" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9Y463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y463" } ] } ] }, { "uniprot_ac": "Q9Y4B6", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y4B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4B6" } ] } ] }, { "uniprot_ac": "Q9Y4K3", "gene_name": "TRAF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9Y4K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9Y4K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K3" } ] } ] }, { "uniprot_ac": "Q9Y4K4", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y4K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y4K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K4" } ] } ] }, { "uniprot_ac": "Q9Y572", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y572" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y572" } ] } ] }, { "uniprot_ac": "Q9Y5S2", "gene_name": "CDC42BPB", 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ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1L0" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9Z1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1L0" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q9Z1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1L0" } ] } ] }, { "uniprot_ac": "Q9Z1M4", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1M4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z1M4", 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"https://www.uniprot.org/uniprot/Q9Z2E3" } ] } ] }, { "uniprot_ac": "Q9Z2P5", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2P5" } ] } ] }, { "uniprot_ac": "Q9Z2R9", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2R9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2R9" } ] } ] }, { "uniprot_ac": "Q9Z2W1", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2W1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2W1" } ] } ] }, { "uniprot_ac": "Q9Z335", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z335" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z335" } ] } ] }, { "uniprot_ac": "X2JAG8", "gene_name": "Prp4k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", 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