{ "uniprot_canonical_ac": "O14628-1", "uniprot_ac": "O14628", "uniprot_id": "ZN195_HUMAN", "mass": { "chemical_mass": 72332.0, "monoisotopic_mass": 72332.0 }, "refseq": { "ac": "NP_001123991", "name": "zinc finger protein 195 isoform 2", "summary": "This gene encodes a protein belonging to the Krueppel C2H2-type zinc-finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15.5, next to an imprinted domain that is associated with maternal-specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991" }, "gene_names": [ { "name": "ZNF195", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O14628", "id": "O14628" }, { "name": "HRF1; ZNFP104", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991", "id": "NP_001123991" }, { "name": "ZNF195", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991", "id": "NP_001123991" }, { "name": "ZNFP104", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O14628", "id": "O14628" } ], "protein_names": [ { "name": "Zinc finger protein 195", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O14628" }, { "name": "krueppel family zinc finger protein (znfp104); hypoxia-regulated factor-1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991", "id": "NP_001123991" }, { "name": "zinc finger protein 195 isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991", "id": "NP_001123991" } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "O14628", "url": "https://www.uniprot.org/uniprot/O14628#function" }, { "database": "UniProtKB", "id": "A0A087WT67", "url": "https://www.uniprot.org/uniprot/A0A087WT67#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprot/ARBA00003767#function" } ] }, { "annotation": "This gene encodes a protein belonging to the Krueppel C2H2-type zinc-finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15.5, next to an imprinted domain that is associated with maternal-specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].", "evidence": [ { "database": "RefSeq", "id": "NP_001123991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991" } ] }, { "annotation": "ZNF195 and SBF1 are potential biomarkers for gemcitabine sensitivity in head and neck squamous cell carcinoma cell lines. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001123991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123991" }, { "database": "PubMed", "id": "24817947", "url": "https://glygen.org/publication/PubMed/24817947" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "78.21", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "73.42", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "77.09", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "49.96", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "84.23", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "93.76", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "58.5", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "83.97", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "86.22", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "47.6", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "82.12", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "89.15", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "87.17", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000005801", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000005801" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "up", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "O14628", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O14628" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", 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"E9PNM0", "url": "https://www.uniprot.org/uniprot/E9PNM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PNM0-1", "url": "https://www.uniprot.org/uniprot/E9PNM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PPF8", "url": "https://www.uniprot.org/uniprot/E9PPF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PPF8-1", "url": "https://www.uniprot.org/uniprot/E9PPF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PSE6", "url": "https://www.uniprot.org/uniprot/E9PSE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PSE6-1", "url": "https://www.uniprot.org/uniprot/E9PSE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YDV1", "url": "https://www.uniprot.org/uniprot/H0YDV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YDV1-1", "url": "https://www.uniprot.org/uniprot/H0YDV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628", "url": "https://www.uniprot.org/uniprot/O14628", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628-1", "url": "https://www.uniprot.org/uniprot/O14628-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628-4", "url": "https://www.uniprot.org/uniprot/O14628-4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628-5", "url": "https://www.uniprot.org/uniprot/O14628-5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628-6", "url": "https://www.uniprot.org/uniprot/O14628-6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628-7", "url": "https://www.uniprot.org/uniprot/O14628-7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14628-8", "url": "https://www.uniprot.org/uniprot/O14628-8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTALCSPGVLQTVKWFLEFRCIFSLAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 629, "header": "sp|O14628-1|ZN195_HUMAN Isoform 1 of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 CANONICAL=O14628-1" }, "isoforms": [ { "isoform_ac": "A0A087WT67-1", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTALCSPGVLQTVKWFLEFRCIFSLAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 633, "header": "tr|A0A087WT67-1|A0A087WT67_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3373591, "end_pos": 3359121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000620374.4", "url": "https://www.ensembl.org/id/ENST00000620374.4" }, { "database": "Ensembl Peptide", "id": "ENSP00000477630.1", "url": "https://www.ensembl.org/id/ENSP00000477630.1" } ] } }, { "isoform_ac": "C9JG37-1", "url": "", "sequence": { "sequence": "MPWAERNLLVYSSSKETLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPAMSSHFTQDLLPEQGIQDAFPKRILRGYG", "length": 119, "header": "tr|C9JG37-1|C9JG37_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3377664, "end_pos": 3360480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000427810.6", "url": "https://www.ensembl.org/id/ENST00000427810.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000390663.2", "url": "https://www.ensembl.org/id/ENSP00000390663.2" } ] } }, { "isoform_ac": "E9PIN4-1", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPGGWE", "length": 79, "header": "tr|E9PIN4-1|E9PIN4_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3370964, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000525313.6", "url": "https://www.ensembl.org/id/ENST00000525313.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000435741.1", "url": "https://www.ensembl.org/id/ENSP00000435741.1" } ] } }, { "isoform_ac": "E9PIT0-1", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPGWKCSGVIVAHCGLHFPGSEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKY", "length": 217, "header": "tr|E9PIT0-1|ZN195_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3360345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000533036.5", "url": "https://www.ensembl.org/id/ENST00000533036.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000433911.1", "url": "https://www.ensembl.org/id/ENSP00000433911.1" } ] } }, { "isoform_ac": "E9PIY8-1", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPALCSPGVLQTVKWFLEFRCIFSLAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAG", "length": 278, "header": "tr|E9PIY8-1|E9PIY8_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3373591, "end_pos": 3360039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000528410.5", "url": "https://www.ensembl.org/id/ENST00000528410.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000431937.1", "url": "https://www.ensembl.org/id/ENSP00000431937.1" } ] } }, { "isoform_ac": "E9PLF5-1", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPGPSVEETILSVL", "length": 91, "header": "tr|E9PLF5-1|E9PLF5_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3373591, "end_pos": 3368821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000532539.1", "url": "https://www.ensembl.org/id/ENST00000532539.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000435153.1", "url": "https://www.ensembl.org/id/ENSP00000435153.1" } ] } }, { "isoform_ac": "E9PLW9-1", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPASANV", "length": 80, "header": "tr|E9PLW9-1|E9PLW9_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3369489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000530643.5", "url": "https://www.ensembl.org/id/ENST00000530643.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000435093.1", "url": "https://www.ensembl.org/id/ENSP00000435093.1" } ] } }, { "isoform_ac": "E9PMX5-1", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHR", "length": 115, "header": "tr|E9PMX5-1|E9PMX5_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3373591, "end_pos": 3361783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000534569.5", "url": "https://www.ensembl.org/id/ENST00000534569.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000437265.1", "url": "https://www.ensembl.org/id/ENSP00000437265.1" } ] } }, { "isoform_ac": "E9PNM0-1", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQK", "length": 131, "header": "tr|E9PNM0-1|E9PNM0_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3373591, "end_pos": 3360411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000529678.5", "url": "https://www.ensembl.org/id/ENST00000529678.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000434715.1", "url": "https://www.ensembl.org/id/ENSP00000434715.1" } ] } }, { "isoform_ac": "E9PPF8-1", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPGQHG", "length": 79, "header": "tr|E9PPF8-1|E9PPF8_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3339812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000528796.5", "url": "https://www.ensembl.org/id/ENST00000528796.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000432720.1", "url": "https://www.ensembl.org/id/ENSP00000432720.1" } ] } }, { "isoform_ac": "E9PSE6-1", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEFHSITQAVVQWCHLSSLQPLLPGLEPSSHFSLLRTWNYRGTPPHPANFCVFNRDRVLPCCPGWSRTPGLK", "length": 146, "header": "tr|E9PSE6-1|E9PSE6_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3366846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000525502.5", "url": "https://www.ensembl.org/id/ENST00000525502.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000434006.1", "url": "https://www.ensembl.org/id/ENSP00000434006.1" } ] } }, { "isoform_ac": "H0YDV1-1", "url": "", "sequence": { "sequence": "GLTVCKPGLITCLEQRKEPWNVKRQEAADGHPGCTFFETGIYSVTQAGSAVV", "length": 52, "header": "tr|H0YDV1-1|H0YDV1_HUMAN Computationally mapped isoform of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=4 SV=1 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3371071, "end_pos": 3362015, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000529228.5", "url": "https://www.ensembl.org/id/ENST00000529228.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000434361.1", "url": "https://www.ensembl.org/id/ENSP00000434361.1" } ] } }, { "isoform_ac": "O14628-1", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTALCSPGVLQTVKWFLEFRCIFSLAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 629, "header": "sp|O14628-1|ZN195_HUMAN Isoform 1 of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3359121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000399602.9", "url": "https://www.ensembl.org/id/ENST00000399602.9" }, { "database": "Ensembl Peptide", "id": "ENSP00000382511.4", "url": "https://www.ensembl.org/id/ENSP00000382511.4" } ] } }, { "isoform_ac": "O14628-4", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 557, "header": "sp|O14628-4|ZN195_HUMAN Isoform 4 of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3359121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000354599.10", "url": "https://www.ensembl.org/id/ENST00000354599.10" }, { "database": "Ensembl Peptide", "id": "ENSP00000346613.6", "url": "https://www.ensembl.org/id/ENSP00000346613.6" } ] } }, { "isoform_ac": "O14628-5", "url": "", "sequence": { "sequence": "MTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 606, "header": "sp|O14628-5|ZN195_HUMAN Isoform 5 of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3379040, "end_pos": 3359121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000005082.13", "url": "https://www.ensembl.org/id/ENST00000005082.13" }, { "database": "Ensembl Peptide", "id": "ENSP00000005082.9", "url": "https://www.ensembl.org/id/ENSP00000005082.9" } ] } }, { "isoform_ac": "O14628-6", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPEMGFHHATQACLELLGSSDLPASASQSAGITGVNHRAQPGLNVSVDKFTAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 610, "header": "sp|O14628-6|ZN195_HUMAN Isoform 6 of Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 CANONICAL=O14628-1" }, "locus": { "chromosome": "11", "start_pos": 3373591, "end_pos": 3359121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000526601.5", "url": "https://www.ensembl.org/id/ENST00000526601.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000435828.1", "url": "https://www.ensembl.org/id/ENSP00000435828.1" } ] } }, { "isoform_ac": "O14628-7", "url": "", "sequence": { "sequence": "MAGAQTLLTFRDVAIEFSLEEWKCLDLAQQNLYRDVMLENYRNLFSVGLTVCKPGLITCLEQRKEPWNVKRQEAADGHPAMSSHFTQDLLPEQGIQDAFPKRILRGYGNCGLDNLYLRKDWESLDECKLQKDYNGLNQCSSTTHSKIFQYNKYVKIFDNFSNLHRRNISNTGEKPFKCQECGKSFQMLSFLTEHQKIHTGKKFQKCGECGKTFIQCSHFTEPENIDTGEKPYKCQECNNVIKTCSVLTKNRIYAGGEHYRCEEFGKVFNQCSHLTEHEHGTEEKPCKYEECSSVFISCSSLSNQQMILAGEKLSKCETWYKGFNHSPNPSKHQRNEIGGKPFKCEECDSIFKWFSDLTKHKRIHTGEKPYKCDECGKAYTQSSHLSEHRRIHTGEKPYQCEECGKVFRTCSSLSNHKRTHSEEKPYTCEECGNIFKQLSDLTKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEECGRVFMWFSDITKHKKTHTGEKPYKCDECGKNFTQSSNLIVHKRIHTGEKPYKCEKCGKAFTQFSHLTVHESIHT", "length": 561, "header": "sp|O14628-7|ZN195_HUMAN Isoform 7 of Zinc 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Schultz DC, Ayyanathan K, Singh PB, Friedman JR, Fredericks WJ, Rauscher FJ 3rd", "evidence": [ { "database": "Reactome", "id": "R-HSA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436" } ], "reference": [ { "type": "PubMed", "id": "10330177", "url": "https://glygen.org/publication/PubMed/10330177" } ] }, { "title": "Transcriptional coactivator complexes.", "journal": "Annual review of biochemistry", "date": "2001", "authors": "Naar AM, Lemon BD, Tjian R", "evidence": [ { "database": "Reactome", "id": "R-HSA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436" } ], "reference": [ { "type": "PubMed", "id": "11395415", "url": "https://glygen.org/publication/PubMed/11395415" } ] }, { "title": "KRAB-containing zinc-finger repressor proteins.", "journal": "Genome biology", "date": "2003", "authors": "Urrutia R", "evidence": [ { "database": "Reactome", "id": "R-HSA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436" } ], "reference": [ { "type": "PubMed", "id": "14519192", "url": "https://glygen.org/publication/PubMed/14519192" } ] }, { "title": "A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.", "journal": "Molecular cell", "date": "2004", "authors": "Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, Fukasawa T, Gustafsson CM, Han M, He X, Herman PK, Hinnebusch AG, Holmberg S, Holstege FC, Jaehning JA, Kim YJ, Kuras L, Leutz A, Lis JT, Meisterernest M, Naar AM, Nasmyth K, Parvin JD, Ptashne M, Reinberg D, Ronne H, Sadowski I, Sakurai H, Sipiczki M, Sternberg PW, Stillman DJ, Strich R, Struhl K, Svejstrup JQ, Tuck S, Winston F, Roeder RG, Kornberg RD", "evidence": [ { "database": "Reactome", "id": "R-HSA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436" } ], "reference": [ { "type": 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"https://glygen.org/publication/PubMed/24817947" } ] }, { "title": "Uncovering global SUMOylation signaling networks in a site-specific manner.", "journal": "Nat. Struct. Mol. Biol.", "date": "2014", "authors": "Hendriks IA, D'Souza RC, Yang B, Verlaan-de Vries M, Mann M, Vertegaal AC", "evidence": [ { "database": "UniProtKB", "id": "O14628", "url": "https://www.uniprot.org/uniprot/O14628" } ], "reference": [ { "type": "PubMed", "id": "25218447", "url": "https://glygen.org/publication/PubMed/25218447" } ] }, { "title": "Kruppel-associated boxes are potent transcriptional repression domains.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1994", "authors": "Margolin JF, Friedman JR, Meyer WK, Vissing H, Thiesen HJ, Rauscher FJ 3rd", "evidence": [ { "database": "Reactome", "id": "R-HSA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436" } ], "reference": [ { "type": "PubMed", "id": "8183939", "url": "https://glygen.org/publication/PubMed/8183939" } ] }, { "title": "KAP-1, a novel corepressor for the highly conserved KRAB repression domain.", "journal": "Genes & development", "date": 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