{ "uniprot_canonical_ac": "O14595-1", "uniprot_ac": "O14595", "uniprot_id": "CTDS2_HUMAN", "mass": { "chemical_mass": 30664.0, "monoisotopic_mass": 30664.0 }, "refseq": { "ac": "NP_005721", "name": "carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" }, "gene_names": [ { "name": "CTDSP2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O14595", "id": "O14595" }, { "name": "CTDSP2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721", "id": "NP_005721" }, { "name": "NIF2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O14595", "id": "O14595" }, { "name": "OS4; PSR2; SCP2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721", "id": "NP_005721" }, { "name": "OS4", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O14595", "id": "O14595" }, { "name": "SCP2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O14595", "id": "O14595" } ], "protein_names": [ { "name": "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O14595" }, { "name": "3.1.3.16", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "NLI-interacting factor 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "Nuclear LIM interactor-interacting factor 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "Protein OS-4", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "SCP2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "Small C-terminal domain phosphatase 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "Small CTD phosphatase 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O14595" }, { "name": "carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721", "id": "NP_005721" }, { "name": "conserved gene amplified in osteosarcoma; nuclear LIM interactor-interacting factor 2; small CTD phosphatase 2; NLI-interacting factor 2; protein OS-4; small C-terminal domain phosphatase 2; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721", "id": "NP_005721" } ], "function": [ { "annotation": "CTDSP2 induces p21(Cip1/Waf1) through increasing the activity of Ras.", "evidence": [ { "database": "RefSeq", "id": "NP_005721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" }, { "database": "PubMed", "id": "25990325", "url": "https://glygen.org/publication/PubMed/25990325" } ] }, { "annotation": "Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595#function" }, { "database": "PubMed", "id": "15681389", "url": "https://glygen.org/publication/PubMed/15681389" }, { "database": "PubMed", "id": "12721286", "url": "https://glygen.org/publication/PubMed/12721286" } ] }, { "annotation": "These results suggest that SCP2 is involved in promoter clearance during steroid-activated transcription.", "evidence": [ { "database": "RefSeq", "id": "NP_005721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" }, { "database": "PubMed", "id": "16724108", "url": "https://glygen.org/publication/PubMed/16724108" } ] }, { "annotation": "Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_005721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" }, { "database": "PubMed", "id": "31774910", "url": "https://glygen.org/publication/PubMed/31774910" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "94.15", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "91.13", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "97.06", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "95.33", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "98.39", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "97.84", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "94.74", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "96.37", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "96.52", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "95.85", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "94.74", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "96.6", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "97.5", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000175215", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000175215" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "O14595", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O14595" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, 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"DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", 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"MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", 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"MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP", "length": 98, "header": "tr|F8W1I1-1|F8W1I1_HUMAN Computationally mapped isoform of CTD small phosphatase 2 OS=Homo sapiens OX=9606 GN=CTDSP2 PE=1 SV=1 CANONICAL=O14595-1" }, "locus": { "chromosome": "12", "start_pos": 57846435, "end_pos": 57823605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000548823.1", "url": "https://www.ensembl.org/id/ENST00000548823.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000447046.1", "url": "https://www.ensembl.org/id/ENSP00000447046.1" } ] } }, { "isoform_ac": "H0YI12-1", "url": "", "sequence": { "sequence": "XFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQVRDSGLIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRK", "length": 182, "header": "tr|H0YI12-1|H0YI12_HUMAN Computationally mapped isoform of CTD small phosphatase 2 OS=Homo sapiens OX=9606 GN=CTDSP2 PE=1 SV=1 CANONICAL=O14595-1" }, "locus": { "chromosome": "12", "start_pos": 57829550, "end_pos": 57823958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000550144.1", "url": "https://www.ensembl.org/id/ENST00000550144.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000448299.1", "url": "https://www.ensembl.org/id/ENSP00000448299.1" } ] } }, { "isoform_ac": "H0YI29-1", "url": "", "sequence": { "sequence": "PINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP", "length": 125, "header": "tr|H0YI29-1|H0YI29_HUMAN Computationally mapped isoform of CTD small phosphatase 2 OS=Homo sapiens OX=9606 GN=CTDSP2 PE=1 SV=1 CANONICAL=O14595-1" }, "locus": { "chromosome": "12", "start_pos": 57826402, "end_pos": 57823605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000549039.5", "url": "https://www.ensembl.org/id/ENST00000549039.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000448386.1", "url": "https://www.ensembl.org/id/ENSP00000448386.1" } ] } }, { "isoform_ac": "O14595-1", "url": "", "sequence": { "sequence": "MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP", "length": 271, "header": "sp|O14595-1|CTDS2_HUMAN Isoform 1 of Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 OS=Homo sapiens OX=9606 GN=CTDSP2 PE=1 SV=2 CANONICAL=O14595-1" }, "locus": { "chromosome": "12", "start_pos": 57846435, "end_pos": 57823605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000398073.7", "url": "https://www.ensembl.org/id/ENST00000398073.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000381148.2", "url": "https://www.ensembl.org/id/ENSP00000381148.2" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 5, "end_pos": 5, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" }, { "database": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" }, { "database": "iPTMnet", "id": "O14595", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14595" } ], "site_lbl": "Ser5" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation.", "journal": "The Journal of cell biology", "date": "1999", "authors": "Yamaguchi A, Hori O, Stern DM, Hartmann E, Ogawa S, Tohyama M", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "10601334", "url": "https://glygen.org/publication/PubMed/10601334" } ] }, { "title": "HEDJ, an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Yu M, Haslam RH, Haslam DB", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "10827079", "url": "https://glygen.org/publication/PubMed/10827079" } ] }, { "title": "Functional analysis of human P5, a protein disulfide isomerase homologue.", "journal": "Journal of biochemistry", "date": "2002", "authors": "Kikuchi M, Doi E, Tsujimoto I, Horibe T, Tsujimoto Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "12204115", "url": "https://glygen.org/publication/PubMed/12204115" } ] }, { "title": "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Yeo M, Lin PS, Dahmus ME, Gill GN", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "reference": [ { "type": "PubMed", "id": "12721286", "url": "https://glygen.org/publication/PubMed/12721286" } ] }, { "title": "A role for the thiol isomerase protein ERP5 in platelet function.", "journal": "Blood", "date": "2005", "authors": "Jordan PA, Stevens JM, Hubbard GP, Barrett NE, Sage T, Authi KS, Gibbins JM", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "15466936", "url": "https://glygen.org/publication/PubMed/15466936" } ] }, { "title": "Small CTD phosphatases function in silencing neuronal gene expression.", "journal": "Science (New York, N.Y.)", "date": "2005", "authors": "Yeo M, Lee SK, Lee B, Ruiz EC, Pfaff SL, Gill GN", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "reference": [ { "type": "PubMed", "id": "15681389", "url": "https://glygen.org/publication/PubMed/15681389" } ] }, { "title": "pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response.", "journal": "The Journal of cell biology", "date": "2006", "authors": "Yoshida H, Oku M, Suzuki M, Mori K", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "16461360", "url": "https://glygen.org/publication/PubMed/16461360" } ] }, { "title": "XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells.", "journal": "Journal of neurochemistry", "date": "2006", "authors": "Kakiuchi C, Ishiwata M, Hayashi A, Kato T", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "16539657", "url": "https://glygen.org/publication/PubMed/16539657" } ] }, { "title": "Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription.", "journal": "The EMBO journal", "date": "2006", "authors": "Thompson J, Lepikhova T, Teixido-Travesa N, Whitehead MA, Palvimo JJ, Janne OA", "evidence": [ { "database": "RefSeq", "id": "NP_005721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" } ], "reference": [ { "type": "PubMed", "id": "16724108", "url": "https://glygen.org/publication/PubMed/16724108" } ] }, { "title": "Structural genomics of protein phosphatases.", "journal": "J. Struct. Funct. Genomics", "date": "2007", "authors": "Almo SC, Bonanno JB, Sauder JM, Emtage S, Dilorenzo TP, Malashkevich V, Wasserman SR, Swaminathan S, Eswaramoorthy S, Agarwal R, Kumaran D, Madegowda M, Ragumani S, Patskovsky Y, Alvarado J, Ramagopal UA, Faber-Barata J, Chance MR, Sali A, Fiser A, Zhang ZY, Lawrence DS, Burley SK", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "reference": [ { "type": "PubMed", "id": "18058037", "url": "https://glygen.org/publication/PubMed/18058037" } ] }, { "title": "Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds.", "journal": "Journal of biochemistry", "date": "2008", "authors": "Yamamoto K, Suzuki N, Wada T, Okada T, Yoshida H, Kaufman RJ, Mori K", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "18664523", "url": "https://glygen.org/publication/PubMed/18664523" } ] }, { "title": "Role of miR-204 in the regulation of apoptosis, endoplasmic reticulum stress response, and inflammation in human trabecular meshwork cells.", "journal": "Investigative ophthalmology & visual science", "date": "2011", "authors": "Li G, Luna C, Qiu J, Epstein DL, Gonzalez P", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "21282569", "url": "https://glygen.org/publication/PubMed/21282569" } ] }, { "title": "Toward a comprehensive characterization of a human cancer cell phosphoproteome.", "journal": "Journal of proteome research", "date": "2013", "authors": "Zhou H, Di Palma S, Preisinger C, Peng M, Polat AN, Heck AJ, Mohammed S", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" }, { "database": "iPTMnet", "id": "O14595", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14595" } ], "reference": [ { "type": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" } ] }, { "title": "FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).", "journal": "The Biochemical journal", "date": "2015", "authors": "Kloet DE, Polderman PE, Eijkelenboom A, Smits LM, van Triest MH, van den Berg MC, Groot Koerkamp MJ, van Leenen D, Lijnzaad P, Holstege FC, Burgering BM", "evidence": [ { "database": "RefSeq", "id": "NP_005721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" } ], "reference": [ { "type": "PubMed", "id": "25990325", "url": "https://glygen.org/publication/PubMed/25990325" } ] }, { "title": "Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer.", "journal": "Bioscience reports", "date": "2019", "authors": "Krasnov GS, Puzanov GA, Afanasyeva MA, Dashinimaev EB, Vishnyakova KS, Beniaminov AD, Adzhubei AA, Kondratieva TT, Yegorov YE, Senchenko VN", "evidence": [ { "database": "RefSeq", "id": "NP_005721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_005721" } ], "reference": [ { "type": "PubMed", "id": "31774910", "url": "https://glygen.org/publication/PubMed/31774910" } ] }, { "title": "Cloning and sequencing of the cDNA encoding human P5.", "journal": "Gene", "date": "1995", "authors": "Hayano T, Kikuchi M", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "7590364", "url": "https://glygen.org/publication/PubMed/7590364" } ] }, { "title": "Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase.", "journal": "Gene", "date": "1996", "authors": "Korth MJ, Lyons CN, Wambach M, Katze MG", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "8666242", "url": "https://glygen.org/publication/PubMed/8666242" } ] }, { "title": "Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family.", "journal": "Genome research", "date": "1997", "authors": "Wise CA, Clines GA, Massa H, Trask BJ, Lovett M", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "9037597", "url": "https://glygen.org/publication/PubMed/9037597" } ] }, { "title": "Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas.", "journal": "Oncogene", "date": "1997", "authors": "Su YA, Lee MM, Hutter CM, Meltzer PS", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "reference": [ { "type": "PubMed", "id": "9315096", "url": "https://glygen.org/publication/PubMed/9315096" } ] }, { "title": "Identification and characterization of a novel member of the EXT gene family, EXTL2.", "journal": "European journal of human genetics : EJHG", "date": "1997", "authors": "Wuyts W, Van Hul W, Hendrickx J, Speleman F, Wauters J, De Boulle K, Van Roy N, Van Agtmael T, Bossuyt P, Willems PJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "9450183", "url": "https://glygen.org/publication/PubMed/9450183" } ] }, { "title": "Structure, chromosomal location, and expression profile of EXTR1 and EXTR2, new members of the multiple exostoses gene family.", "journal": "Biochemical and biophysical research communications", "date": "1998", "authors": "Saito T, Seki N, Yamauchi M, Tsuji S, Hayashi A, Kozuma S, Hori T", "evidence": [ { "database": "Reactome", "id": "R-HSA-381038", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038" } ], "reference": [ { "type": "PubMed", "id": "9473480", "url": "https://glygen.org/publication/PubMed/9473480" } ] } ], "pathway": [ { "id": "hsa:10106", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:10106", "resource": "KEGG Pathway" }, { "id": "R-HSA-381038", "name": "XBP1(S) activates chaperone genes", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-381038", "resource": "Reactome", "description": "XBP1(S) activates chaperone genes" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BX07-1", "protein_name": "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2", "gene_name": "Ctdsp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRSIFKALLCCFHTQHVVQSSSSTELTHKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEQDQGRICVVIDLDETLVHSSFKPINNADFIVPVEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFREACVFHQGCYVKDLSRLGRDLRKTVILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPVFEELSGTDDVYTSLGQLRAP", "length": 270 }, "evidence": [ { "id": "45930429", "url": "http://www.informatics.jax.org/homology/45930429", "database": "MGI" }, { "id": "O14595", "url": "https://omabrowser.org/oma/group/O14595/", "database": "OMA" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" }, { "name": "myosin phosphatase activity", "id": "GO:0017018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017018", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of protein phosphorylation", "id": "GO:0001933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001933", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" }, { "name": "protein dephosphorylation", "id": "GO:0006470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006470", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "O14595", "url": "https://www.uniprot.org/uniprot/O14595" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q4KLK9-1", "P62142-1", "Q3SWT6-1", "Q5I0E6-1", "Q5FWT7-1", "Q3B7T6-1", "B4F7B7-1", "Q5FVI9-1", "P63329-1", "P20651-1", "Q66H71-1", "Q80Z30-1", "Q91XQ2-1", "B2RZ50-1", "P63088-1", "Q64346-1", "P0C595-1", "Q6AXW7-1", "Q62767-1", "Q63340-1", "O54838-1", "Q64623-1", "Q9JIM4-1", "P63331-1", "O54857-1", "Q9Z1Z6-1", "F1LNI5-1", "Q562B5-1", "Q641Y6-1", "P20650-1", "P35815-1", "P62138-1", "Q5BJ92-1", "Q5M821-1", "Q5XIS1-1", "Q9WTR8-1", "Q9WVR7-1", "Q64620-1", "P53042-1", "P62716-1", "P0C089-1", "A0A8I6AF61-1", "A0A0G2K9N1-1", "D4A520-1", "A0A0G2K0J7-1", "D3ZNK9-1", "D3ZP99-1", "D4A3W6-1", "E2CWF0-1", "D3ZN69-1", "Q2YDV1-1", "M0R5X1-1", "D3ZBG7-1", "B1WC24-1", "Q8VD52-1", "M0R4W4-1", "A6HQ12-1", "A0A8I5ZU99-1", "A6K136-1", "Q8NI37-1", "P36873-1", "Q9Y5B0-1", "P62140-1", "Q9UNH5-1", "A4D256-1", "O60729-1", "Q16667-1", "P51452-1", "O95476-1", "O14595-1", "O15194-1", "Q9BV47-1", "P62136-1", "Q9BVJ7-1", "Q9H1R2-1", "Q9BY84-1", "Q9NRW4-1", "Q16828-1", "Q9H596-1", "Q13202-1", "Q4G0W2-1", "Q99956-1", "Q8NEJ0-1", "Q6B8I1-1", "B3EWF7-1", "P28562-1", "Q16690-1", "Q13115-1", "Q9GZU7-1", "Q9UNI6-1", "Q9Y6W6-1", "Q68J44-1", "Q16829-1", "Q8WTR2-1", "Q9BRF8-1", "O95147-1", "Q9UII6-1", "Q9H0C8-1", "Q99502-1", "Q9ULR3-1", "P60510-1", "P49593-1", "O15297-1", "Q5SGD2-1", "O15355-1", "Q8WY54-2", "Q8N819-1", "Q5JR12-1", "O75688-1", "O14830-1", "O14829-1", "P16298-1", "Q8IXW5-1", "O60346-1", "Q6ZVD8-1", "P67775-1", "P48454-1", "P53041-1", "O00743-1", "Q96MI6-5", "Q8WUK0-1", "P35813-1", "P62714-1", "Q96HS1-1", "Q08209-1", "P60484-1", "Q8N3J5-1", "Q8TE77-1", "Q76I76-1", "Q8WVY7-1", "Q9NP77-1", "Q8WYL5-1", "Q96GD0-1", "A0A1W2PQ27-1", "A0A1W2PR75-1", "A0A1W2PQC6-1", "A0A1W2PQD8-1", "A0A1W2PQJ5-1", "A0A1W2PQ64-1", "Q92562-1", "P63087-1", "Q9D7X3-1", "Q6PFY9-1", "Q3TP92-1", "P58465-1", "P58466-1", "Q7TSG2-1", "Q8BFS6-1", "Q6GQT0-1", "Q810P3-1", "Q8R4V2-1", "Q99N11-1", "Q9JLY7-1", "Q9WUA5-1", "O09112-1", "Q8BTR5-1", "Q9DBB1-1", "Q9D700-1", "Q8BX07-1", "Q9QYJ7-1", "Q8VE01-1", "Q91Z46-1", "P28563-1", "Q8K4T5-1", "Q6NT99-1", "Q8BK84-1", "Q8BFV3-1", "P97767-1", "Q9D0T2-1", "Q9D9D8-1", "Q9ESS0-1", "Q8R0F6-1", "Q149T7-1", "Q3UYC0-1", "P62141-1", "O35385-1", "Q8BX10-1", "Q6NVE9-1", "Q8BU27-3", "Q80TL0-1", "Q8BGL1-1", "Q8BHN0-1", "Q8CGA0-1", "Q9QZ67-1", "O35655-1", "P97470-1", "Q8BXA7-1", "Q8CHE4-1", "P49443-1", "Q61074-1", "Q5SW75-1", "P62715-1", "P63328-1", "Q8K330-1", "Q9CY97-1", "P62137-1", "P36993-1", "P48453-1", "P48455-1", "Q60676-1", "Q66GT5-1", "Q76I79-1", "Q9CQR6-1", "Q8VC34-1", "P63330-1", "O08586-1", "Q8BXN7-1", "Q8BGR9-1", "P60487-1", "Q91WF7-1", "P14747-1", "P20604-1", "P23594-1", "P23595-1", "P25646-1", "P26570-1", "P32598-1", "P33329-1", "P38757-1", "P38797-1", "P23287-1", "P53043-1", "P32345-1", "P32838-1", "P32945-1", "P38148-1", "P39966-1", "P40084-1", "P53538-1", "P34221-1", "P35182-1", "P38089-1", "Q03254-1", "Q12378-1", "Q54GL8-1", "Q54IJ8-1", "Q54M72-1", "Q54M73-1", "Q54QE5-1", "Q558Z3-1", "Q54R42-1", "Q55E39-1", "Q54T01-1", "Q54T76-1", "Q54WS9-1", "Q556S4-1", "Q55BI8-1", "Q55CS8-1", "Q8ST13-1", "Q9U9A3-1", "Q75JA4-1", "O15757-1", "O15743-1", "Q54RD6-1", "Q54Y32-1", "Q556Y8-1", "Q55CS7-1", "Q7YSW8-1", "Q9XYL0-1", "Q9XZE5-1", "Q9Y0B7-1", "Q8T9S7-1", "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q86BN8-1", "Q9VJ07-1", "P12982-1", "P48462-1", "M9PFN0-1", "O46084-1", "Q9VRG7-1", "P23696-1", "Q27889-1", "Q9VXF1-1", "X2JEB8-1", "A8QI94-1", "P48456-1", "Q9VWE4-1", "Q9VVW5-1", "Q9VWF4-1", "Q7KVM5-1", "Q9XZ16-1", "Q9VQL9-1", "Q9W0E2-1", "Q9W3R1-1", "Q5LJN2-1", "Q9W2A5-1", "Q9W147-1", "Q7KMQ6-1", "Q961C5-1", "Q9W173-1", "M9PI51-1", "Q9VZS0-1", "Q7JY68-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P62142-1", "Q3SWT6-1", "Q4KLK9-1", "Q5I0E6-1", "P20651-1", "Q5FWT7-1", "A0A0G2JYA4-1", "Q3B7T6-1", "B4F7B7-1", "Q5FVI9-1", "P63329-1", "Q66H71-1", "Q80Z30-1", "Q91XQ2-1", "B2RZ50-1", "P63088-1", "Q64346-1", "P0C595-1", "Q6AXW7-1", "Q62767-1", "Q63340-1", "O54838-1", "Q64623-1", "Q9JIM4-1", "P63331-1", "O54857-1", "Q9Z1Z6-1", "Q9WVR7-1", "F1LNI5-1", "P20650-1", "P35815-1", "P62138-1", "Q562B5-1", "Q5BJ92-1", "Q5M821-1", "Q5XIS1-1", "Q641Y6-1", "Q9WTR8-1", "Q64620-1", "P53042-1", "P62716-1", "P0C089-1", "A0A8I6AF61-1", "A0A0G2K9N1-1", "Q2YDV1-1", "E2CWF0-1", "D4A520-1", "D3ZN69-1", "A0A0G2K0J7-1", "D3ZNK9-1", "D4A3W6-1", "F1M4Q5-1", "M0R5X1-1", "A0A8I6B0P9-1", "D3ZBG7-1", "B1WC24-1", "M0R4W4-1", "A6HQ12-1", "A0A8I5ZU99-1", "Q8NI37-1", "P36873-1", "P60510-1", "Q16667-1", "Q9Y5B0-1", "P48454-1", "Q08209-1", "P53041-1", "P62140-1", "P62714-1", "Q9UNH5-1", "A4D256-1", "O60729-1", "P51452-1", "O95476-1", "O14595-1", "O15194-1", "O14829-1", "Q9BV47-1", "P62136-1", "O95147-1", "Q9BVJ7-1", "Q9H1R2-1", "Q9BY84-1", "Q9NRW4-1", "Q16828-1", "Q9H596-1", "Q13202-1", "Q4G0W2-1", "Q99956-1", "Q8NEJ0-1", "Q6B8I1-1", "B3EWF7-1", "P28562-1", "Q16690-1", "Q13115-1", "Q9GZU7-1", "Q9UNI6-1", "Q9Y6W6-1", "Q05923-1", "Q68J44-1", "Q16829-1", "Q8WTR2-1", "Q9BRF8-1", "Q9UII6-1", "Q9H0C8-1", "Q99502-1", "Q9ULR3-1", "P49593-1", "O15297-1", "Q5SGD2-1", "O15355-1", "Q8IXW5-1", "Q8WY54-2", "Q8N819-1", "Q5JR12-1", "O75688-1", "O14830-1", "O60346-1", "Q6ZVD8-1", "P67775-1", "P16298-1", "O00743-1", "Q96MI6-5", "Q8WUK0-1", "P35813-1", "Q96HS1-1", "P60484-1", "Q8TE77-1", "Q76I76-1", "Q8WYL5-1", "Q8WVY7-1", "Q9NP77-1", "A0A1W2PQ27-1", "A0A1W2PR75-1", "A0A1W2PQC6-1", "A0A1W2PQD8-1", "A0A1W2PQJ5-1", "A0A1W2PQ64-1", "P63087-1", "P48453-1", "Q9D7X3-1", "O35655-1", "Q9CQR6-1", "Q6PFY9-1", "Q3TP92-1", "P58465-1", "P58466-1", "Q7TSG2-1", "Q8BFS6-1", "Q6GQT0-1", "Q810P3-1", "Q8R4V2-1", "Q99N11-1", "Q9JLY7-1", "Q9WUA5-1", "O09112-1", "Q8BTR5-1", "Q9DBB1-1", "Q9D700-1", "Q8BX07-1", "Q9QYJ7-1", "Q8VE01-1", "Q91Z46-1", "P28563-1", "Q8K4T5-1", "Q6NT99-1", "Q8BK84-1", "Q8BFV3-1", "Q05922-1", "P97767-1", "Q9D0T2-1", "Q9D9D8-1", "Q9ESS0-1", "Q8R0F6-1", "Q149T7-1", "Q3UYC0-1", "P62141-1", "O35385-1", "Q8BX10-1", "Q6NVE9-1", "Q8BU27-3", "Q80TL0-1", "Q8BGL1-1", "Q8BHN0-1", "Q8CGA0-1", "Q9QZ67-1", "Q76I79-1", "P97470-1", "Q8BXA7-1", "Q8CHE4-1", "P49443-1", "Q61074-1", "Q5SW75-1", "P62715-1", "P63328-1", "Q8VC34-1", "Q8K330-1", "Q9CY97-1", "P62137-1", "P36993-1", "P48455-1", "Q60676-1", "Q66GT5-1", "P63330-1", "O08586-1", "Q7TNL7-1", "Q8BGR9-1", "Q1HL35-1", "P14747-1", "P20604-1", "P23594-1", "P23595-1", "P25646-1", "P26570-1", "P32598-1", "P33329-1", "P38757-1", "P38797-1", "P23287-1", "P53043-1", "P32345-1", "P32838-1", "P32945-1", "P38148-1", "P39966-1", "P40084-1", "P53538-1", "P34221-1", "P35182-1", "P38089-1", "Q03254-1", "Q12378-1", "Q54GL8-1", "Q54IJ8-1", "Q54M72-1", "Q54M73-1", "Q54QE5-1", "Q558Z3-1", "Q54R42-1", "Q54T01-1", "Q54T76-1", "Q54WS9-1", "Q556S4-1", "Q55BI8-1", "Q55CS8-1", "Q55E39-1", "Q8ST13-1", "Q9U9A3-1", "Q75JA4-1", "O15743-1", "O15757-1", "Q54RD6-1", "Q54Y32-1", "Q556Y8-1", "Q55CS7-1", "Q7YSW8-1", "Q9XYL0-1", "Q9XZE5-1", "Q9Y0B7-1", "Q8T9S7-1", "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q9VJ07-1", "P12982-1", "P48462-1", "Q86BN8-1", "O46084-1", "Q9VRG7-1", "P23696-1", "Q27889-1", "Q9VXF1-1", "X2JEB8-1", "A8QI94-1", "Q9VVW5-1", "P48456-1", "Q9VWE4-1", "Q9VWF4-1", "Q7KVM5-1", "Q9XZ16-1", "Q95TV5-1", "Q9VQL9-1", "Q9W0E2-1", "Q9W3R1-1", "Q5LJN2-1", "Q9W2A5-1", "Q9W147-1", "Q7KMQ6-1", "Q961C5-1", "Q9W173-1", "M9PI51-1", "Q9VZS0-1", "Q7JY68-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] }, { "id": "R-HSA-1791130", "name": "Expression of CTDSP2", "equation": "", "summary": "The CTDSP2 gene is transcribed to yield mRNA and the mRNA is translated to yield protein.", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-HSA-5642237" ], "output_participant_list": [ "R-HSA-535488" ], "enzyme_list": [ "O14595-1" ], "evidence": [ { "id": "R-HSA-1791130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1791130" } ] } ], "reaction_participants": [ { "participant_id": "R-HSA-535488", "participant_name": "CTDSP2 [nucleoplasm]", "crossref": [ { "id": "O14595", "database": "GeneCards", "url": "" }, { "id": "HMDBP11650", "database": "HMDB Protein", "url": "" }, { "id": "ENSG00000175215", "database": "Ensembl", "url": "" }, { "id": "2Q5E", "database": "PDB", "url": "" }, { "id": "NP_005721.3", "database": "RefSeq", "url": "" }, { "id": "ENST00000398073", "database": "Ensembl", "url": "" }, { "id": "O14595", "database": "UniProt", "url": "" }, { "id": "ENSG00000175215-CTDSP2", "database": "HPA", "url": "" }, { "id": "O14595", "database": "Pharos - Targets", "url": "" }, { "id": "3.1.3.16", "database": "IntEnz", "url": "" }, { "id": "ENSG00000175215", "database": "OpenTargets", "url": "" }, { "id": "ENSP00000381148", "database": "Ensembl", "url": "" }, { "id": "O14595", "database": "PRO", "url": "" } ] }, { "participant_id": "R-HSA-5642237", "participant_name": "CTDSP2 gene [nucleoplasm]", "crossref": [ { "id": "ENSG00000175215", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0G2JYA4", "gene_name": "LOC100362453", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2JYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JYA4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2JYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JYA4" } ] } ] }, { "uniprot_ac": "A0A0G2K0J7", "gene_name": "Ctdp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K0J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K0J7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2K0J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K0J7" } ] } ] }, { "uniprot_ac": "A0A0G2K9N1", "gene_name": "Dusp13b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A0G2K9N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K9N1" } ] } ] }, { "uniprot_ac": "A0A1W2PQ27", "gene_name": "SSU72L1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1W2PQ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1W2PQ27" } ] } ] }, { "uniprot_ac": "A0A1W2PQ64", "gene_name": "SSU72L5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1W2PQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1W2PQ64" } ] } ] }, { "uniprot_ac": "A0A1W2PQC6", "gene_name": "SSU72L4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1W2PQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1W2PQC6" } ] } ] }, { "uniprot_ac": "A0A1W2PQD8", "gene_name": "SSU72L2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1W2PQD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1W2PQD8" } ] } ] }, { "uniprot_ac": "A0A1W2PQJ5", "gene_name": "SSU72L3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1W2PQJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1W2PQJ5" } ] } ] }, { "uniprot_ac": "A0A1W2PR75", "gene_name": "SSU72L6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1W2PR75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1W2PR75" } ] } ] }, { "uniprot_ac": "A0A8I5ZU99", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I5ZU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZU99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8I5ZU99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZU99" } ] } ] }, { "uniprot_ac": "A0A8I6AF61", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8I6AF61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AF61" } ] } ] }, { "uniprot_ac": "A0A8I6B0P9", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8I6B0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B0P9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8I6B0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6B0P9" } ] } ] }, { "uniprot_ac": "A4D256", "gene_name": "CDC14C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A4D256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4D256" } ] } ] }, { "uniprot_ac": "A6HQ12", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A6HQ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HQ12" } ] } ] }, { "uniprot_ac": "A6K136", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6K136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K136" } ] }, { "ec_number": "3.1.3.52", "activity": "H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A6K136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K136" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6K136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6K136" } ] } ] }, { "uniprot_ac": "A8DYY5", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8DYY5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8DYY5" } ] } ] }, { "uniprot_ac": "A8QI94", "gene_name": "Pp1-Y1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A8QI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8QI94" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A8QI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A8QI94" } ] } ] }, { "uniprot_ac": "B1WC24", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B1WC24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WC24" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B1WC24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WC24" } ] } ] }, { "uniprot_ac": "B2RZ50", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B2RZ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RZ50" } ] } ] }, { "uniprot_ac": "B3EWF7", "gene_name": "EPM2A", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B3EWF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B3EWF7" } ] } ] }, { "uniprot_ac": "B4F7B7", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "B4F7B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B4F7B7" } ] } ] }, { "uniprot_ac": "D3ZBG7", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBG7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZBG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBG7" } ] } ] }, { "uniprot_ac": "D3ZN69", "gene_name": "Ppef2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZN69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZN69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZN69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZN69" } ] } ] }, { "uniprot_ac": "D3ZNK9", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZNK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZNK9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZNK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZNK9" } ] } ] }, { "uniprot_ac": "D3ZP99", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D3ZP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D3ZP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP99" } ] } ] }, { "uniprot_ac": "D4A3W6", "gene_name": "Dusp16", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D4A3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3W6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D4A3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3W6" } ] } ] }, { "uniprot_ac": "D4A520", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "D4A520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A520" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "D4A520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A520" } ] } ] }, { "uniprot_ac": "E2CWF0", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E2CWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E2CWF0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E2CWF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E2CWF0" } ] } ] }, { "uniprot_ac": "F1LNI5", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1LNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNI5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1LNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNI5" } ] } ] }, { "uniprot_ac": "F1M4Q5", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1M4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M4Q5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1M4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M4Q5" } ] } ] }, { "uniprot_ac": "M0R4W4", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M0R4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R4W4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M0R4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R4W4" } ] } ] }, { "uniprot_ac": "M0R5X1", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M0R5X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R5X1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M0R5X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R5X1" } ] } ] }, { "uniprot_ac": "M9PFN0", "gene_name": "hzg", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PFN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PFN0" } ] } ] }, { "uniprot_ac": "M9PI51", "gene_name": "Dmel\\CG10089", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI51" } ] } ] }, { "uniprot_ac": "O00743", "gene_name": "PPP6C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O00743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00743" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O00743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00743" } ] } ] }, { "uniprot_ac": "O08586", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O08586", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08586" } ] } ] }, { "uniprot_ac": "O09112", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O09112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09112" } ] } ] }, { "uniprot_ac": "O14595", "gene_name": "CTDSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O14595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O14595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14595" } ] } ] }, { "uniprot_ac": "O14829", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O14829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O14829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14829" } ] } ] }, { "uniprot_ac": "O14830", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O14830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O14830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14830" } ] } ] }, { "uniprot_ac": "O15194", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15194", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15194" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15194", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15194" } ] } ] }, { "uniprot_ac": "O15297", "gene_name": "PPM1D", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15297", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15297" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15297", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15297" } ] } ] }, { "uniprot_ac": "O15355", "gene_name": "PPM1G", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15355" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15355" } ] } ] }, { "uniprot_ac": "O15743", "gene_name": "spnA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15743" } ] } ] }, { "uniprot_ac": "O15757", "gene_name": "pppB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O15757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15757" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O15757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15757" } ] } ] }, { "uniprot_ac": "O35385", "gene_name": "Ppef2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O35385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35385" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O35385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35385" } ] } ] }, { "uniprot_ac": "O35655", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O35655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35655" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O35655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35655" } ] } ] }, { "uniprot_ac": "O46084", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O46084" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O46084" } ] } ] }, { "uniprot_ac": "O54838", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O54838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54838" } ] } ] }, { "uniprot_ac": "O54857", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "O54857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54857" } ] } ] }, { "uniprot_ac": "O60346", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O60346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60346" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O60346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60346" } ] } ] }, { "uniprot_ac": "O60729", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O60729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60729" } ] } ] }, { "uniprot_ac": "O75688", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O75688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75688" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O75688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75688" } ] } ] }, { "uniprot_ac": "O76932", "gene_name": "Pp4-19C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76932" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76932" } ] } ] }, { "uniprot_ac": "O95147", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O95147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95147" } ] } ] }, { "uniprot_ac": "O95476", "gene_name": "CTDNEP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O95476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95476" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O95476", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95476" } ] } ] }, { "uniprot_ac": "P0C089", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "P0C089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C089" } ] } ] }, { "uniprot_ac": "P0C595", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P0C595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C595" } ] } ] }, { "uniprot_ac": "P11612", "gene_name": "PpY-55A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11612" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11612" } ] } ] }, { "uniprot_ac": "P12982", "gene_name": "Pp1-87B", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12982" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12982" } ] } ] }, { "uniprot_ac": "P14747", "gene_name": "CMP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P14747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14747" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P14747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14747" } ] } ] }, { "uniprot_ac": "P16298", "gene_name": "PPP3CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P16298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16298" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P16298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16298" } ] } ] }, { "uniprot_ac": "P20604", "gene_name": "SIT4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P20604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20604" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P20604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20604" } ] } ] }, { "uniprot_ac": "P20650", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P20650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20650" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P20650", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20650" } ] } ] }, { "uniprot_ac": "P20651", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P20651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20651" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P20651", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20651" } ] } ] }, { "uniprot_ac": "P23287", "gene_name": "CNA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23287" } ] } ] }, { "uniprot_ac": "P23594", "gene_name": "PPH21", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23594" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23594" } ] } ] }, { "uniprot_ac": "P23595", "gene_name": "PPH22", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23595" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23595" } ] } ] }, { "uniprot_ac": "P23696", "gene_name": "mts", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23696" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23696" } ] } ] }, { "uniprot_ac": "P25646", "gene_name": "PTC6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] }, { "ec_number": "3.1.3.43", "activity": "H2O + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "P25646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25646" } ] } ] }, { "uniprot_ac": "P26570", "gene_name": "PPZ1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P26570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26570" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P26570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26570" } ] } ] }, { "uniprot_ac": "P28562", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P28562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28562" } ] } ] }, { "uniprot_ac": "P28563", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P28563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28563" } ] } ] }, { "uniprot_ac": "P32345", "gene_name": "PPH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32345" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32345" } ] } ] }, { "uniprot_ac": "P32598", "gene_name": "GLC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32598" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32598" } ] } ] }, { "uniprot_ac": "P32838", "gene_name": "PPG1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32838" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32838" } ] } ] }, { "uniprot_ac": "P32945", "gene_name": "PPQ1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P32945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32945" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P32945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32945" } ] } ] }, { "uniprot_ac": "P33329", "gene_name": "PPZ2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P33329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33329" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P33329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33329" } ] } ] }, { "uniprot_ac": "P34221", "gene_name": "PTC3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P34221", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34221" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P34221", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34221" } ] } ] }, { "uniprot_ac": "P35182", "gene_name": "PTC1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P35182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35182" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P35182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35182" } ] } ] }, { "uniprot_ac": "P35813", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P35813", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35813" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P35813", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35813" } ] } ] }, { "uniprot_ac": "P35815", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P35815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35815" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P35815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35815" } ] } ] }, { "uniprot_ac": "P36873", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P36873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36873" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P36873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36873" } ] } ] }, { "uniprot_ac": "P36993", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P36993", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36993" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P36993", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36993" } ] } ] }, { "uniprot_ac": "P38089", "gene_name": "PTC4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38089" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38089" } ] } ] }, { "uniprot_ac": "P38148", "gene_name": "PPS1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P38148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38148" } ] } ] }, { "uniprot_ac": "P38757", "gene_name": "NEM1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38757" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38757" } ] } ] }, { "uniprot_ac": "P38797", "gene_name": "PTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P38797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38797" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P38797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38797" } ] } ] }, { "uniprot_ac": "P39966", "gene_name": "PTC2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P39966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39966" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P39966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39966" } ] } ] }, { "uniprot_ac": "P40084", "gene_name": "RTR1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P40084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40084" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P40084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40084" } ] } ] }, { "uniprot_ac": "P40421", "gene_name": "rdgC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40421" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40421" } ] } ] }, { "uniprot_ac": "P48453", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48453" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48453" } ] } ] }, { "uniprot_ac": "P48454", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48454" } ] } ] }, { "uniprot_ac": "P48455", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48455" } ] } ] }, { "uniprot_ac": "P48456", "gene_name": "CanA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48456" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48456" } ] } ] }, { "uniprot_ac": "P48461", "gene_name": "Pp1alpha-96A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48461" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48461" } ] } ] }, { "uniprot_ac": "P48462", "gene_name": "flw", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48462" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48462" } ] } ] }, { "uniprot_ac": "P49443", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P49443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49443" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P49443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49443" } ] } ] }, { "uniprot_ac": "P49593", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P49593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49593" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P49593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49593" } ] } ] }, { "uniprot_ac": "P51452", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P51452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51452" } ] } ] }, { "uniprot_ac": "P53041", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53041" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53041" } ] } ] }, { "uniprot_ac": "P53042", "gene_name": "Ppp5c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53042" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53042" } ] } ] }, { "uniprot_ac": "P53043", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53043" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53043" } ] } ] }, { "uniprot_ac": "P53538", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P53538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53538" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P53538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53538" } ] } ] }, { "uniprot_ac": "P58465", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P58465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58465" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P58465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58465" } ] } ] }, { "uniprot_ac": "P58466", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P58466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58466" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P58466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58466" } ] } ] }, { "uniprot_ac": "P60484", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P60484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60484" } ] } ] }, { "uniprot_ac": "P60487", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine.", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "P60487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60487" } ] } ] }, { "uniprot_ac": "P60510", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P60510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60510" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P60510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60510" } ] } ] }, { "uniprot_ac": "P62136", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62136" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62136" } ] } ] }, { "uniprot_ac": "P62137", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62137" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62137" } ] } ] }, { "uniprot_ac": "P62138", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62138" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62138" } ] } ] }, { "uniprot_ac": "P62140", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] }, { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62140", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62140" } ] } ] }, { "uniprot_ac": "P62141", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62141" } ] } ] }, { "uniprot_ac": "P62142", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] }, { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62142" } ] } ] }, { "uniprot_ac": "P62714", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62714", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62714" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62714", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62714" } ] } ] }, { "uniprot_ac": "P62715", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62715" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62715" } ] } ] }, { "uniprot_ac": "P62716", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62716" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62716" } ] } ] }, { "uniprot_ac": "P63087", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63087", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63087" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63087", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63087" } ] } ] }, { "uniprot_ac": "P63088", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63088" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63088" } ] } ] }, { "uniprot_ac": "P63328", "gene_name": "Ppp3ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63328" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63328" } ] } ] }, { "uniprot_ac": "P63329", "gene_name": "Ppp3ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63329" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63329" } ] } ] }, { "uniprot_ac": "P63330", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63330" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63330" } ] } ] }, { "uniprot_ac": "P63331", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P63331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63331" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P63331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63331" } ] } ] }, { "uniprot_ac": "P67775", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67775" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P67775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67775" } ] } ] }, { "uniprot_ac": "P97470", "gene_name": "Ppp4c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P97470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97470" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P97470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97470" } ] } ] }, { "uniprot_ac": "P97767", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P97767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97767" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + 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{ "id": "Q61074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61074" } ] } ] }, { "uniprot_ac": "Q62767", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q62767", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62767" } ] } ] }, { "uniprot_ac": "Q63340", "gene_name": "Dusp7", "activity": [ { 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"url": "https://www.uniprot.org/uniprot/Q641Y6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q641Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Y6" } ] } ] }, { "uniprot_ac": "Q64346", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q64346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64346" } ] } ] }, { "uniprot_ac": "Q64620", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q64620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64620" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q64620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64620" } ] } ] }, { "uniprot_ac": "Q64623", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q64623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64623" } ] } ] }, { "uniprot_ac": "Q66GT5", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q66GT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66GT5" } ] } ] }, { "uniprot_ac": "Q66H71", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q66H71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H71" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q66H71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H71" } ] } ] }, { "uniprot_ac": "Q68J44", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q68J44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q68J44" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q68J44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q68J44" } ] } ] }, { "uniprot_ac": "Q6AXW7", "gene_name": "Dusp18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6AXW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6AXW7" } ] } ] }, { "uniprot_ac": "Q6B8I1", "gene_name": "DUSP13A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6B8I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B8I1" } ] } ] }, { "uniprot_ac": "Q6GQT0", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6GQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6GQT0" } ] } ] }, { "uniprot_ac": "Q6NN85", "gene_name": "ssh", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NN85" } ] } ] }, { "uniprot_ac": "Q6NT99", "gene_name": "Dusp23", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6NT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NT99" } ] } ] }, { "uniprot_ac": "Q6NVE9", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NVE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NVE9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NVE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6NVE9" } ] } ] }, { "uniprot_ac": "Q6PFY9", "gene_name": "Cdc14b", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6PFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PFY9" } ] } ] }, { "uniprot_ac": "Q6ZVD8", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6ZVD8", "database": "UniProtKB", "url": 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"id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q76I76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I76" } ] } ] }, { "uniprot_ac": "Q76I79", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q76I79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76I79" } ] } ] }, { "uniprot_ac": "Q7JY68", "gene_name": "BEST:LP01468", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7JY68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7JY68" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7JY68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7JY68" } ] } ] }, { "uniprot_ac": "Q7K4Q5", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7K4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7K4Q5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7K4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7K4Q5" } ] } ] }, { "uniprot_ac": "Q7KMQ6", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "Q7KMQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KMQ6" } ] } ] }, { "uniprot_ac": "Q7KVM5", "gene_name": "PpN58A", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KVM5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7KVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KVM5" } ] } ] }, { "uniprot_ac": "Q7TNL7", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7TNL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL7" } ] } ] }, { "uniprot_ac": "Q7TSG2", "gene_name": "Ctdp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7TSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSG2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7TSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSG2" } ] } ] }, { "uniprot_ac": "Q7YSW8", "gene_name": "canA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7YSW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7YSW8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7YSW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7YSW8" } ] } ] }, { "uniprot_ac": "Q80TL0", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q80TL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TL0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q80TL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TL0" } ] } ] }, { "uniprot_ac": "Q80Z30", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q80Z30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Z30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q80Z30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Z30" } ] } ] }, { "uniprot_ac": "Q810P3", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q810P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810P3" } ] } ] }, { "uniprot_ac": "Q86BN8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86BN8" } ] } ] }, { "uniprot_ac": "Q8BFS6", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFS6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BFS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFS6" } ] } ] }, { "uniprot_ac": "Q8BFV3", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BFV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BFV3" } ] } ] }, { "uniprot_ac": "Q8BGL1", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BGL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BGL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGL1" } ] } ] }, { "uniprot_ac": "Q8BGR9", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGR9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGR9" } ] } ] }, { "uniprot_ac": "Q8BHN0", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BHN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BHN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHN0" } ] } ] }, { "uniprot_ac": "Q8BK84", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BK84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK84" } ] } ] }, { "uniprot_ac": "Q8BTR5", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8BTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTR5" } ] } ] }, { "uniprot_ac": "Q8BU27", "gene_name": "Ppm1m", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BU27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BU27" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BU27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BU27" } ] } ] }, { "uniprot_ac": "Q8BX07", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX07" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX07" } ] } ] }, { "uniprot_ac": "Q8BX10", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BX10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX10" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BX10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BX10" } ] } ] }, { "uniprot_ac": "Q8BXA7", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXA7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXA7" } ] } ] }, { "uniprot_ac": "Q8BXN7", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8BXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXN7" } ] }, { "ec_number": "3.1.3.52", "activity": "H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "Q8BXN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BXN7" } ] } ] }, { "uniprot_ac": "Q8CGA0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8CGA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CGA0" } ] } ] }, { "uniprot_ac": "Q8CHE4", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8CHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHE4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8CHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CHE4" } ] } ] }, { "uniprot_ac": "Q8IXW5", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8IXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IXW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8IXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IXW5" } ] } ] }, { "uniprot_ac": "Q8K330", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K330", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K330" } ] } ] }, { "uniprot_ac": "Q8K4T5", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8K4T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K4T5" } ] } ] }, { "uniprot_ac": "Q8N3J5", "gene_name": "PPM1K", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8N3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N3J5" } ] }, { "ec_number": "3.1.3.52", "activity": "H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "Q8N3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N3J5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8N3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N3J5" } ] } ] }, { "uniprot_ac": "Q8N819", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8N819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N819" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8N819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N819" } ] } ] }, { "uniprot_ac": "Q8NEJ0", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8NEJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEJ0" } ] } ] }, { "uniprot_ac": "Q8NI37", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8NI37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NI37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8NI37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NI37" } ] } ] }, { "uniprot_ac": "Q8R0F6", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R0F6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8R0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R0F6" } ] } ] }, { "uniprot_ac": "Q8R4V2", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8R4V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V2" } ] } ] }, { "uniprot_ac": "Q8ST13", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8ST13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8ST13" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8ST13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8ST13" } ] } ] }, { "uniprot_ac": "Q8T9S7", "gene_name": "pteN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "Q8T9S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9S7" } ] } ] }, { "uniprot_ac": "Q8TE77", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8TE77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TE77" } ] } ] }, { "uniprot_ac": "Q8VC34", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VC34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VC34" } ] } ] }, { "uniprot_ac": "Q8VD52", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine.", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD52" } ] } ] }, { "uniprot_ac": "Q8VE01", "gene_name": "Dusp18", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8VE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VE01" } ] } ] }, { "uniprot_ac": "Q8WTR2", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WTR2" } ] } ] }, { "uniprot_ac": "Q8WUK0", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.27", "activity": "1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q8WUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WUK0" } ] } ] }, { "uniprot_ac": "Q8WVY7", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WVY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WVY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WVY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WVY7" } ] } ] }, { "uniprot_ac": "Q8WY54", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WY54" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WY54" } ] } ] }, { "uniprot_ac": "Q8WYL5", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q8WYL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WYL5" } ] } ] }, { "uniprot_ac": "Q91WF7", "gene_name": "Fig4", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q91WF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91WF7" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q91WF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91WF7" } ] }, { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "Q91WF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91WF7" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "Q91WF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91WF7" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "Q91WF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91WF7" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "Q91WF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91WF7" } ] } ] }, { "uniprot_ac": "Q91XQ2", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] }, { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q91XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XQ2" } ] } ] }, { "uniprot_ac": "Q91Z46", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q91Z46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z46" } ] } ] }, { "uniprot_ac": "Q92562", "gene_name": "FIG4", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q92562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92562" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q92562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92562" } ] }, { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "Q92562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92562" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "Q92562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92562" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "Q92562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92562" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "Q92562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92562" } ] } ] }, { "uniprot_ac": "Q95TV5", "gene_name": "Dmel\\CG11597", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q95TV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95TV5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q95TV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95TV5" } ] } ] }, { "uniprot_ac": "Q961C5", "gene_name": "alph", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q961C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q961C5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q961C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q961C5" } ] } ] }, { "uniprot_ac": "Q96GD0", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "H2O + pyridoxine 5'-phosphate = phosphate + pyridoxine.", "evidence": [ { "id": "Q96GD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD0" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q96GD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD0" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "Q96GD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q96GD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD0" } ] } ] }, { "uniprot_ac": "Q96HS1", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q96HS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96HS1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q96HS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96HS1" } ] } ] }, { "uniprot_ac": "Q96MI6", "gene_name": "PPM1M", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q96MI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96MI6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q96MI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96MI6" } ] } ] }, { "uniprot_ac": "Q99502", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q99502", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99502" } ] } ] }, { "uniprot_ac": "Q99956", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q99956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99956" } ] } ] }, { "uniprot_ac": "Q99N11", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q99N11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N11" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q99N11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N11" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q99N11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q99N11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N11" } ] } ] }, { "uniprot_ac": "Q9BRF8", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRF8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9BRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRF8" } ] } ] }, { "uniprot_ac": "Q9BV47", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BV47" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BV47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9BV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BV47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9BV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BV47" } ] } ] }, { "uniprot_ac": "Q9BVJ7", "gene_name": "DUSP23", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BVJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVJ7" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BVJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVJ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9BVJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVJ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9BVJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVJ7" } ] } ] }, { "uniprot_ac": "Q9BY84", "gene_name": "DUSP16", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BY84" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9BY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BY84" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9BY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BY84" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9BY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BY84" } ] } ] }, { "uniprot_ac": "Q9CQR6", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9CQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQR6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9CQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQR6" } ] } ] }, { "uniprot_ac": "Q9CY97", "gene_name": "Ssu72", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9CY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CY97" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9CY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CY97" } ] } ] }, { "uniprot_ac": "Q9D0T2", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D0T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9D0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D0T2" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D0T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9D0T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D0T2" } ] } ] }, { "uniprot_ac": "Q9D700", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D700" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D700" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9D700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D700" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9D700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D700" } ] } ] }, { "uniprot_ac": "Q9D7X3", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D7X3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9D7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D7X3" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D7X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9D7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D7X3" } ] } ] }, { "uniprot_ac": "Q9D9D8", "gene_name": "Dusp21", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D9D8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9D9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D9D8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9D9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D9D8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9D9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D9D8" } ] } ] }, { "uniprot_ac": "Q9DBB1", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9DBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBB1" } ] } ] }, { "uniprot_ac": "Q9ESS0", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9ESS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESS0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9ESS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESS0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9ESS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESS0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9ESS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESS0" } ] } ] }, { "uniprot_ac": "Q9GZU7", "gene_name": "CTDSP1", 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