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"https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", 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"MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the 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"DISABLED", "database": "UniCarbKB", "categories": [ "Glycoproteomics" ] }, { "id": "A0A1W2PNT1", "url": "https://www.uniprot.org/uniprot/A0A1W2PNT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2PNT1-1", "url": "https://www.uniprot.org/uniprot/A0A1W2PNT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2PS86", "url": "https://www.uniprot.org/uniprot/A0A1W2PS86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2PS86-1", "url": "https://www.uniprot.org/uniprot/A0A1W2PS86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C9JYL7", "url": "https://www.uniprot.org/uniprot/C9JYL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C9JYL7-1", "url": "https://www.uniprot.org/uniprot/C9JYL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H7C187", "url": "https://www.uniprot.org/uniprot/H7C187", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H7C187-1", "url": "https://www.uniprot.org/uniprot/H7C187-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14513", "url": "https://www.uniprot.org/uniprot/O14513", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14513-1", "url": "https://www.uniprot.org/uniprot/O14513-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14513-2", "url": "https://www.uniprot.org/uniprot/O14513-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14513-3", "url": "https://www.uniprot.org/uniprot/O14513-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O14513-4", "url": "https://www.uniprot.org/uniprot/O14513-4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDAEVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKNLRKRQSSQNWDKRLSIDSSLPSGFASPTNELPPTRIKESHILEGLRKLQKRKVLLEPPSVITKWGYKDCMNSNEGIYSPGIKSSSLKEYPPCKTADLGSPCKEPHKTFVYDLDSHVDADDDPSTLALLQAVPNQSCRPHGSKLTHSVSDSLFGWETNRKHFLEGTSSVYPKERPEKLTSCASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNETFDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT", "length": 1909, "header": "sp|O14513-1|NCKP5_HUMAN Isoform 1 of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 CANONICAL=O14513-1" }, "isoforms": [ { "isoform_ac": "A0A1W2PNT1-1", "url": "", "sequence": { "sequence": "XSNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQKLRQLEETKDDPENRLSKISLESFNKFNSNTVILLEKEKNSLNKVEGQKEEKEKNEETSLSSSDRPGVDNLESLSDSLYDSFSSCASQGSNDV", "length": 244, "header": "tr|A0A1W2PNT1-1|NCKP5_HUMAN Computationally mapped isoform of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=1 CANONICAL=O14513-1" }, "locus": { "chromosome": "2", "start_pos": 132732051, "end_pos": 132673026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000640590.1", "url": "https://www.ensembl.org/id/ENST00000640590.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000490966.1", "url": "https://www.ensembl.org/id/ENSP00000490966.1" } ] } }, { "isoform_ac": "A0A1W2PS86-1", "url": "", "sequence": { "sequence": "XSNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSEIETT", "length": 110, "header": "tr|A0A1W2PS86-1|NCKP5_HUMAN Computationally mapped isoform of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=1 CANONICAL=O14513-1" }, "locus": { "chromosome": "2", "start_pos": 132732051, "end_pos": 132673291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000639875.1", "url": "https://www.ensembl.org/id/ENST00000639875.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000492746.1", "url": "https://www.ensembl.org/id/ENSP00000492746.1" } ] } }, { "isoform_ac": "C9JYL7-1", "url": "", "sequence": { "sequence": "MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAM", "length": 69, "header": "tr|C9JYL7-1|NCKP5_HUMAN Computationally mapped isoform of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=1 CANONICAL=O14513-1" }, "locus": { "chromosome": "2", "start_pos": 133517526, "end_pos": 133213716, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000358991.4", "url": "https://www.ensembl.org/id/ENST00000358991.4" }, { "database": "Ensembl Peptide", "id": "ENSP00000351882.4", "url": "https://www.ensembl.org/id/ENSP00000351882.4" } ] } }, { "isoform_ac": "H7C187-1", "url": "", "sequence": { "sequence": "XQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRRRKM", "length": 114, "header": "tr|H7C187-1|H7C187_HUMAN Computationally mapped isoform of NCK associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=1 CANONICAL=O14513-1" }, "locus": { "chromosome": "2", "start_pos": 133517513, "end_pos": 133123785, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000427594.5", "url": "https://www.ensembl.org/id/ENST00000427594.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000399070.1", "url": "https://www.ensembl.org/id/ENSP00000399070.1" } ] } }, { "isoform_ac": "O14513-1", "url": "", "sequence": { "sequence": "MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDAEVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKNLRKRQSSQNWDKRLSIDSSLPSGFASPTNELPPTRIKESHILEGLRKLQKRKVLLEPPSVITKWGYKDCMNSNEGIYSPGIKSSSLKEYPPCKTADLGSPCKEPHKTFVYDLDSHVDADDDPSTLALLQAVPNQSCRPHGSKLTHSVSDSLFGWETNRKHFLEGTSSVYPKERPEKLTSCASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNETFDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLCGSPEEEEKQVPIPSETRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPAGPKAEHTELLPQGIACLQPRAAARDYTFFKRSEEDTEKNIPKDNVDNVPRVSTESFSSRTVTQNPQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQKSKLMEPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFELRSDPHIPKHSAQLPHSSRMPSRRDWVQCPKSQTPGSRSRPAIESSDSGEPPTRDEHCGSGPEAGVKSPSPPPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISSNPATTEVQRKKPSVAFKKPIFTHPMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHSFSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPSVGRPSGHPSSGKGSLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSKLETSGRHPDASATATDAVSSEAPLSPTIEEKVMLCIQENVEKGQVQTKPTSVEAKQKPGPSFASWFGFRKSRLPALSSRKMDISKTKVEKKDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKDTKSADNPDGGLQSKNNRRTPQDIYNQLKIEPRNRHSPVACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSSQGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT", "length": 1909, "header": "sp|O14513-1|NCKP5_HUMAN Isoform 1 of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 CANONICAL=O14513-1" }, "locus": { "chromosome": "2", "start_pos": 133517526, "end_pos": 132673292, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000409261.6", "url": "https://www.ensembl.org/id/ENST00000409261.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000387128.1", "url": "https://www.ensembl.org/id/ENSP00000387128.1" } ] } }, { "isoform_ac": "O14513-2", "url": "", "sequence": { "sequence": "MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRVRPTSDLLLQKLHSRLLDLSSGDLLSEVERNRSLTQSRTDAEVHEHQLNTKSALKCPGLGAVIPGHLCPRNSYSSSSELSLSSTCSEYSSGSSYTWHDGKNLRKRVKEANENLQEDEDDAVADSVFQSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSMRAQTLEREVPSSTDGQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQNEAEPRPQTCSSFGYAEDPMASQPLPDWGSEVAATGTQDKAPRMCTYSASGGSNSDSDLDYGDNGFGAGRGQLVKALKSAAPEIETT", "length": 590, "header": "sp|O14513-2|NCKP5_HUMAN Isoform 2 of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 CANONICAL=O14513-1" }, "locus": { "chromosome": "2", "start_pos": 133517526, "end_pos": 132673292, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000409213.5", "url": "https://www.ensembl.org/id/ENST00000409213.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000386952.1", "url": "https://www.ensembl.org/id/ENSP00000386952.1" } ] } }, { "isoform_ac": "O14513-3", "url": "", "sequence": { "sequence": "MDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALEKHGWNWRPLS", "length": 178, "header": "sp|O14513-3|NCKP5_HUMAN Isoform 3 of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 CANONICAL=O14513-1" }, "locus": {} }, { "isoform_ac": "O14513-4", "url": "", "sequence": { "sequence": "MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHLRLQSEKRLQEVTLESERNRIQMRSLQQQFSRRRKM", "length": 118, "header": "sp|O14513-4|NCKP5_HUMAN Isoform 4 of Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 CANONICAL=O14513-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 113, "start_aa": "Ser", "end_pos": 113, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "O14513", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "id": "30379171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30379171" }, { "id": "37217939", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37217939" }, { "id": "38253038", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38253038" }, { "id": "29351928", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29351928" }, { "id": "O14513", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O14513" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 1328, "start_aa": "Ser", "end_pos": 1328, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1328", "evidence": [ { "id": "O14513", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "id": "30379171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30379171" }, { "id": "37217939", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37217939" }, { "id": "38253038", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38253038" }, { "id": "29351928", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29351928" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 1351, "start_aa": "Ser", "end_pos": 1351, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1351", "evidence": [ { "id": "O14513", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "id": "30379171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30379171" }, { "id": "37217939", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37217939" }, { "id": "38253038", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38253038" }, { "id": "29351928", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29351928" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 1354, "start_aa": "Ser", "end_pos": 1354, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1354", "evidence": [ { "id": "O14513", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "id": "30379171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30379171" }, { "id": "37217939", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37217939" }, { "id": "38253038", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38253038" }, { "id": "29351928", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29351928" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 1376, "start_aa": "Ser", "end_pos": 1376, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1376", "evidence": [ { "id": "O14513", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "id": "30379171", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30379171" }, { "id": "37217939", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37217939" }, { "id": "38253038", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38253038" }, { "id": "29351928", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29351928" }, { "id": "O14513", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O14513" } ] }, { "glytoucan_ac": "G70994MS", "type": "O-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "", "start_pos": 1376, "start_aa": "Ser", "end_pos": 1376, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1376", "evidence": [ { "id": "GLY_000142", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000142" }, { "id": "29351928", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29351928" } ] }, { "glytoucan_ac": "G09528DL", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 585, "start_aa": "Asn", "end_pos": 585, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn585", "evidence": [ { "id": "O14513", "database": "UniCarbKB", "url": "" }, { "id": "23345538", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23345538" } ] }, { "glytoucan_ac": "G10773YW", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 585, "start_aa": "Asn", "end_pos": 585, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn585", "evidence": [ { "id": "758", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/758" }, { "id": "23345538", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23345538" } ] } ], "phosphorylation": [ { "start_pos": 1181, "end_pos": 1181, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O14513", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14513" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser1181" }, { "start_pos": 1182, "end_pos": 1182, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O14513", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14513" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser1182" }, { "start_pos": 1188, "end_pos": 1188, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O14513", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14513" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser1188" }, { "start_pos": 1193, "end_pos": 1193, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O14513", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14513" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser1193" }, { "start_pos": 1202, "end_pos": 1202, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O14513", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14513" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Thr1202" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Genome-wide association study of bipolar disorder in European American and African American individuals.", "journal": "Molecular psychiatry", "date": "2009", "authors": "Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, Koller DL, Lawson WB, Liu C, Lohoff F, McInnis MG, McMahon FJ, Mirel DB, Murray SS, Nievergelt C, Nurnberger J, Nwulia EA, Paschall J, Potash JB, Rice J, Schulze TG, Scheftner W, Panganiban C, Zaitlen N, Zandi PP, Zollner S, Schork NJ, Kelsoe JR", "evidence": [ { "database": "RefSeq", "id": "NP_997246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997246" } ], "reference": [ { "type": "PubMed", "id": "19488044", "url": "https://glygen.org/publication/PubMed/19488044" } ] }, { "title": "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.", "journal": "Science signaling", "date": "2010", "authors": "Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M", "evidence": [ { "database": "iPTMnet", "id": "O14513-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O14513-1" } ], "reference": [ { "type": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ] }, { "title": "A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.", "journal": "Schizophrenia research", "date": "2010", "authors": "Wang KS, Liu XF, Aragam N", "evidence": [ { "database": "RefSeq", "id": "NP_997246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997246" } ], "reference": [ { "type": "PubMed", "id": "20889312", "url": "https://glygen.org/publication/PubMed/20889312" } ] }, { "title": "Glycoproteomic analysis of the secretome of human endothelial cells.", "journal": "Molecular & cellular proteomics : MCP", "date": "2013", "authors": "Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M", "evidence": [ { "database": "UniCarbKB", "id": "O14513", "url": "" }, { "database": "GlyConnect", "id": "758", "url": "https://glyconnect.expasy.org/browser/proteins/758" } ], "reference": [ { "type": "PubMed", "id": "23345538", "url": "https://glygen.org/publication/PubMed/23345538" } ] }, { "title": "Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.", "journal": "Nature genetics", "date": "2013", "authors": "Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, Stewart C, Bandla S, Imamura Y, Schumacher SE, Shefler E, McKenna A, Carter SL, Cibulskis K, Sivachenko A, Saksena G, Voet D, Ramos AH, Auclair D, Thompson K, Sougnez C, Onofrio RC, Guiducci C, Beroukhim R, Zhou Z, Lin L, Lin J, Reddy R, Chang A, Landrenau R, Pennathur A, Ogino S, Luketich JD, Golub TR, Gabriel SB, Lander ES, Beer DG, Godfrey TE, Getz G, Bass AJ", "evidence": [ { "database": "dbSNP", "id": "rs531375141", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs531375141" } ], "reference": [ { "type": "PubMed", "id": "23525077", "url": "https://glygen.org/publication/PubMed/23525077" } ] }, { "title": "Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag).", "journal": "Molecular & cellular proteomics : MCP", "date": "2018", "authors": "Woo CM, Lund PJ, Huang AC, Davis MM, Bertozzi CR, Pitteri SJ", "evidence": [ { "database": "O-GlcNAc Database", "id": "O14513", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "database": "O-GlcNAc Atlas", "id": "O14513", "url": "https://oglcnac.org/atlas/detail/O14513" }, { "database": "GlyGen", "id": "GLY_000142", "url": "https://data.glygen.org/GLY_000142" } ], "reference": [ { "type": "PubMed", "id": "29351928", "url": "https://glygen.org/publication/PubMed/29351928" } ] }, { "title": "A triarylphosphine-trimethylpiperidine reagent for the one-step derivatization and enrichment of protein post-translational modifications and identification by mass spectrometry.", "journal": "Chemical communications (Cambridge, England)", "date": "2018", "authors": "Huo B, Zhang W, Zhao X, Dong H, Yu Y, Wang J, Qian X, Qin W", "evidence": [ { "database": "O-GlcNAc Database", "id": "O14513", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" }, { "database": "O-GlcNAc Atlas", "id": "O14513", "url": "https://oglcnac.org/atlas/detail/O14513" } ], "reference": [ { "type": "PubMed", "id": "30379171", "url": "https://glygen.org/publication/PubMed/30379171" } ] }, { "title": "Extracellular arginine availability modulates eIF2\u03b1 O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.", "journal": "Journal of biomedical science", "date": "2023-05-22", "authors": "Hung Yu-Wen, Ouyang Ching, Ping Xiaoli, Qi Yue, Wang Yi-Chang, Kung Hsing-Jien, Ann David K", "evidence": [ { "database": "O-GlcNAc Database", "id": "O14513", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" } ], "reference": [ { "type": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" } ] }, { "title": "Studying the O-GlcNAcome of human placentas using banked tissue samples.", "journal": "Glycobiology", "date": "2024-01-22", "authors": "Luna Sarai, Malard Florian, Pereckas Michaela, Aoki Mayumi, Aoki Kazahiro, Olivier-Van Stichelen Stephanie", "evidence": [ { "database": "O-GlcNAc Database", "id": "O14513", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O14513" } ], "reference": [ { "type": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" } ] }, { "title": "A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1997", "authors": "Matuoka K, Miki H, Takahashi K, Takenawa T", "evidence": [ { "database": "UniProtKB", "id": "O14513", "url": "https://www.uniprot.org/uniprot/O14513" } ], "reference": [ { "type": "PubMed", "id": "9344857", "url": "https://glygen.org/publication/PubMed/9344857" } ] } ], "pathway": [ { "id": "hsa:344148", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:344148", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9QAE1-1", "protein_name": "NCK-associated protein 5", "gene_name": "Nckap5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGKRQLDRRDFGKRLSLDSSLVEYMDSNKCIEHLLAQLREQHRSLWREKLAVARLQREVAQRTSQGAMHEKLIHELEEERHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKITAYQEGLPDEERKEQAALGDLHVVAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSALALENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRVRPASDVLLQEHLQNAKSGTPALKHSGSGVVIPDHLCPRNSCSSGSELSLSSTCSEYSSGSSYTWQDRKLIGKRQSSRIWDKRLSIDSSLPSGFASPADELPPTRIKESHILEGLRKLQKRKVFLESPSLVISKWGYKDCMNSNEGIYSPGIKTSSLKECPPCQPSGMGIPCQNLHQTFIYDANSHEDAHEELPSSALPLTSPSQGYRIQGSKLTHSVSDSLFNWEPHRKYFAEGTASVYTREMPERLARCASHCPLERKLCPSIHLPWVQRDRDPHSQVHGHVPLNLQLSDTDDNETLNELHIESSDERSPSDLSLTGDTDKSMENLEVGFRKSEGGSRDMGEEACPTHLETSPKAFSFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEISISSALAGPSEELTELSPQEITHFQAGATARDCPFLKRPEEETAKNIPKDENHILTAPNDFFSSQTIITQNSPRPKLAKPTQGVAWQSNSRPVGNMGVYTKQGLTKIPSRGKSSPQKSKLVESMPTMLVPSSALVTPEKTPASPMGKLSQCRKAESPGSLCDVQPESHIPKHPAQVPHIPKISNKKNWVQCPRSQTSGIQSRHLMGRSDSSEMRSNGCVSAPQTRMRSPSPPTPPGRSVSLLVRPSYDYPPLPSPAKPETQGPGDAVSPGLKSPLLKGSSAPLVSSSPVMSEIQKKPSVASRKSAFPPALPSTQAVVHTRYPEHIASSPFAVTTSGPPKVSPKRGIPKPPPHHALGTAHMDTDLQTPKTCPSSCELLEVTSCKSLSPGRKRQLSDSTVMPHRPSFSGVNESLTPQVNSPSSSSSSCRNQGSSQGGQNSPEKGPKTRLPVGLKVLMKSPQLLKKTSLVPGKQEKDSLNEASRSCVAANTSNPEDSKDPASLETSRDERTTALLGVRGPDSLARGLALDSTMPESLECSISRDDGRDGADSRAIKRSFSSSKPHLKPALGMNGAKARSQSFSIHLGEKPSTPPTEGPGKIRTQIITNTAERGNSLTRQNISMEGSPSKTPSVSTSDNLPNAGRPLGNPFSRQSSLCSTGSSSSQHGSPSKLPLRMLTRPEGLLTPGVEDQRLSTQEECPERGVHEQSSSDHHRHPSPLSDCPQFLHVPGRMQRPSNLETSGISKLETSGRHPDASSTGTSVVSPEAPLSPSIEEKVMLCIQENVEKGQVQTKSASVEVKPRAGPSFTSWFGFRKSRLPALSSRRMEASKSKVEKKDTKLKSERKKEKKKAEVQSKIENELSRGTKKADGQSPDDGLQSSESLKVSQDIYNQMKLEPRNRPSPAVCPTKDAFMTELLNRVDKRASVQRESGSKGVSCRSVLEGTSQGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNEDVQEDEEDRVADTTLQSHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASMASSARAQTLDREVPSSTDSQSSPESMIIHSISDPSMMAREMRASQSHLPKPTSSGKPSFEKQNGAESKAHTGPSFEYAEDAVASEPLSGWRGEDATTETQEPKQVEETKEDPENRLSEISLESFNKFSSNTVILLGKEKSPSEVEGQKEEKGKKTEVSSSSSERPGVDRVESLSDSLYDSFSSCASQASNEA", "length": 1909 }, "evidence": [ { "id": "45935062", "url": "http://www.informatics.jax.org/homology/45935062", "database": "MGI" }, { "id": "O14513", "url": "https://omabrowser.org/oma/group/O14513/", "database": "OMA" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LU96-1", "protein_name": "NCK-associated protein 5", "gene_name": "Nckap5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGKRQLDRRDFGKRLSLDSSLVEYMDSNKCIEHLLAQLREQHRSLWREKLAVARLQREVAQRTSQGAMQEKLIHELEEERQLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKITAYQERVSEEERKEQAALGDLRVEADEDSRSEHSSTEGGKEDSRLLLKRLKALEAENSALALENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSILFQQRVRPASDVLLQEHLQNAKSGAPALKHSGSGVVIPDHPCPRNSCSSGSELSLSSTCSEYSSGSSYTWQDRKLNGKRQTSQIWDKRLSIDSSLPSGFTSPADELPPTRIKESHILEGLRKLQKRKVLLESPASVMSKWGYKDCMNSNEGIYSPGIKNSSLKECPPCQSPGRGIPCQNLHQTFNYDANSHEYAHEEFLSSASPRTSPSQGCRIQSSKLTHSVSDSLFTWEPHRKYFAEGTASVYTREMPERLTRCASHCPLERKLCPSVHLPWVQRDRDPHSQGPGHVPLNLQLSDTDDNETLHELHIESSDERSPSDLSLTGDTDRSMENLGVKFGKSECVSHDKGKEECPTHLETSPKAFSFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEISISSTPAGPSEELTELSPQGITHFQPGATARDYPFLGRPEEEPKTNIPKDENGILTAPNDSFNSPTTVTQNSPRPKLVKPTQGVAWQSNSRSVANMSVYTKQGLTKIPSRSKISPQKSKLVDPMPTTLVPSSGLGTLAKTPASPTGKLSQCTNAESPGTFCDVQPESHIPKHPTQLPHIPKISNKKNWVQCPKSQTAGIQSRHLMGKSDNGESPTRAKRCGSEPKTRMRSPSPPTPPGRSVSLLVRPSYDYPPLPSPAKPETKAPGDTVSTGLKSPVLKGSSAPLVSSSPAMSEIQKKPSVASRKSAFPTALPSTQAVVHTRYPEHTSSSPFAVTAPGPTKVSPKRGIPKAPHPQALGTTHMDTDLQTPKTRPSSYELLEMTSCKNLSPGRKGQLSDSTVTPHRPSFSGPNEFLTPQVNSTSSSSSSCRNQGTSQGGQNPPEKGPKTRLPVGLRVLMKSPQLLRKTSMVPGKQEKDSLNEASRSSVTANKSNPEDSKDPASLETSRDERTTALLGLRGPESLARGLGLESTPPESLESSISRDDGRDGVDSRAIKRSFSSSKPHLKPALGMNGAKARSQSFSFHLGEKPSTPPIEGPGKIRTQIITNTAERGNSLTRQNISMEGSPSKTPSVSTPDNLPNAGRPLGNPFSRQGSLCSTGSSSSQHGSPSKLPLRMLTRPEGLLTPEEEDQRFSTQEECPGRGVHEQSSSNHHRHPSSTLSDCPQSLQVPGRIQRPSNLETNGISKLETSGRHPDASPTGTSVVSPEAPLSPSIEEKVMLCIQENVEKGQAQTKSASVEVKPRAGPSFTSWFGFRKSRLPALSSRRMEASKSKVEKKDTKLKSERKKEKKKAEVQSKRENELSRGTKKADGQSPDDGLQNTESLKATQDIYNQMKSEPRNRPSPAVSPTKDAFMTELLNRVDKRAALQTESGSKGVSCRSVLEGTSQGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVDEDVREDEEDRVADAALQSHVIESNCQMRTLDSGIGTFPLPDSGNRSMGRYICQQDSPEDTDPLLPLQPAPSMPSSARAQTLDREVPSSTDSQSSSESTIIHSVSDPSMMARGIRASQSHLPKPTTSGKTSFEKQNGAESKATTGPSFEYAEDAVPSEPLSGWRGEDATTENQELKQVEETKEDPENRLSEISLESFNKFNSNTVILLEKEQSPSEVEGQKEEKGKETEVSLSSSDRPGVDHVESLSDSLYDSFSSCASQTSNA", "length": 1910 }, "evidence": [ { "id": "45935062", "url": "http://www.informatics.jax.org/homology/45935062", "database": "MGI" }, { "id": "O14513", "url": "https://omabrowser.org/oma/group/O14513/", "database": "OMA" } ], "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "O14513", "url": "https://www.uniprot.org/uniprot/O14513" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "microtubule depolymerization", "id": "GO:0007019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007019", "evidence": [ { "database": "UniProtKB", "id": "O14513", "url": "https://www.uniprot.org/uniprot/O14513" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "O14513", "url": "https://www.uniprot.org/uniprot/O14513" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "Nck-associated protein 5 N-glycosylated 1 (human)", "definition": "A Nck-associated protein 5 (human) that has been N-glycosylated at the residue equivalent to Asn-585 of the amino acid sequence represented by UniProtKB:O14513-1, in which the glycan composition is represented by GlyTouCan:G09528DL. Example: UniProtKB:O14513-1, Asn-585, MOD:00160~GNO:G09528DL. [PRO:DNx, PMID:23345538]", "evidence": [ { "id": "PR:000050696", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000050696" } ] } ], "site_annotation": [ { "start_pos": 1093, "end_pos": 1095, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1207, "end_pos": 1209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1316, "end_pos": 1318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1639, "end_pos": 1641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1732, "end_pos": 1734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 779, "end_pos": 781, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 585 ], "o_linked_sites": [ 113, 1328, 1351, 1354, 1376 ], "snv_sites": [ 103, 123, 173, 205, 207, 379, 504, 536, 556, 585, 587, 611, 728, 787, 843, 890, 904, 946, 962, 982, 1079, 1131, 1163, 1271, 1301, 1306, 1351, 1357, 1376, 1457, 1526, 1572, 1614, 1667, 1690, 1733 ], "glycation_sites": [], "phosphorylation_sites": [ 1181, 1182, 1188, 1193, 1202 ], "sequon_annotation_sites": [ { "start_pos": 1093, "end_pos": 1095 }, { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 1186, "end_pos": 1188 }, { "start_pos": 1207, "end_pos": 1209 }, { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 1316, "end_pos": 1318 }, { "start_pos": 1639, "end_pos": 1641 }, { "start_pos": 1732, "end_pos": 1734 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 699, "end_pos": 701 }, { "start_pos": 779, "end_pos": 781 }, { "start_pos": 799, "end_pos": 801 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 8 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycans", "count": 2 }, { "field": "o_linked_glycan_sites", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 8 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycans", "count": 2 }, { "field": "o_linked_glycan_sites", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 39 }, { "field": "total_sites", "count": 36 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 9 }, { "field": "total_sites", "count": 9 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 30 }, { "field": "total_sites", "count": 27 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl", "subjects_tested", "subjects_positive", "frequency" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }