{ "uniprot_canonical_ac": "O00841-1", "uniprot_ac": "O00841", "uniprot_id": "CUDA_DICDI", "mass": { "chemical_mass": 91743.0, "monoisotopic_mass": 91743.0 }, "refseq": { "ac": "XP_638542", "name": "hypothetical protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638542" }, "gene_names": [ { "name": "cudA", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O00841", "id": "O00841" }, { "name": "DDB_G0284465", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O00841", "id": "O00841" }, { "name": "cudA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638542", "id": "XP_638542" } ], "protein_names": [ { "name": "Putative transcriptional regulator cudA", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O00841" }, { "name": "hypothetical protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638542", "id": "XP_638542" } ], "function": [ { "annotation": "Essential for normal culmination. May function as a transcriptional regulator.", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841#function" }, { "database": "PubMed", "id": "9226443", "url": "https://glygen.org/publication/PubMed/9226443" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "common_name": "Cellular slime molds" } ], "gene": [ { "name": "cudA", "url": "https://www.uniprot.org/uniprot/O00841", "locus": {} } ], "crossref": [ { "id": "DDB_G0284465", "url": "http://dictybase.org/gene/DDB_G0284465", "database": "dictyBase", "categories": [ "Organism-specific" ] }, { "id": "8624635", "url": "https://www.ncbi.nlm.nih.gov/gene/8624635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040430", "url": 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"MNQSQNFHNIDLGHYGAQGSNQSFNNNNNGNNGMMMNQQQMQQHVVPHLHHLQQQQQQPQQQQLRNVPDYSNSPNGTTNGSTMSPNCINTNNNNNNNNNNNNNSNNNNNNNNNASNNLTSNKSSSTNTPQIGQLQASPANLTNSPSAISSPITISNNSSLNSPSTTSSPNLLLNGTSNKRIMISQQTCLVEEKFSKNGVQKNVHVVVKNNPFLLTLSLLDSSLNFHQLTPEVQLVYDSESLKEVDSATVKPLEYKTRANEEGDQLTIELRIKVLSSQLEDMLFRAKVKIVDPRTRKETHGLSVITHPIRVVSKPDQVKKKAKKRKRAPTDSLMDTLNRIEHQQKEQQRLLKKLCYHDKENNIIQLIQQQQQQQQLLNNVTNNINNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTSTTTTTTTTTSSCNNNNNNNNENNEHIVKIENTECNNNNNNIINNTENDENINKPILNSKDEFQSAFKEFIGAFKQLQCLDPDGADGAFKINTCANDAQTMCEILEMVKVELKKDENFKDKCGGSSGGACGENNPDNPCSCKVCPYKQKVDHINQSYETYFNMFNPSNSNSVVPQQSQQLQQQQIQQQQQSQQQVQQQQQQQMQQQPQQQQQQPQQQQQNQQQGQQPQQQQQQGQLDYTTYIDPQLQMQQQLQMQQAAQQQYMQQTMDQQQQQQYYMQQYHLQQQQQQQQAQRYLMQQQYMQQQAQQQQQQHQQVAIQQQQQQNQQQNQQQNQQQQNQSPQNQQSLDFQNANNFIDFNSGLGFMNFPNINFGDMGFSAV", "length": 802, "header": "sp|O00841-1|CUDA_DICDI Isoform 1 of Putative transcriptional regulator cudA OS=Dictyostelium discoideum OX=44689 GN=cudA PE=1 SV=2 CANONICAL=O00841-1" }, "isoforms": [ { "isoform_ac": "O00841-1", "url": "", "sequence": { "sequence": "MNQSQNFHNIDLGHYGAQGSNQSFNNNNNGNNGMMMNQQQMQQHVVPHLHHLQQQQQQPQQQQLRNVPDYSNSPNGTTNGSTMSPNCINTNNNNNNNNNNNNNSNNNNNNNNNASNNLTSNKSSSTNTPQIGQLQASPANLTNSPSAISSPITISNNSSLNSPSTTSSPNLLLNGTSNKRIMISQQTCLVEEKFSKNGVQKNVHVVVKNNPFLLTLSLLDSSLNFHQLTPEVQLVYDSESLKEVDSATVKPLEYKTRANEEGDQLTIELRIKVLSSQLEDMLFRAKVKIVDPRTRKETHGLSVITHPIRVVSKPDQVKKKAKKRKRAPTDSLMDTLNRIEHQQKEQQRLLKKLCYHDKENNIIQLIQQQQQQQQLLNNVTNNINNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTSTTTTTTTTTSSCNNNNNNNNENNEHIVKIENTECNNNNNNIINNTENDENINKPILNSKDEFQSAFKEFIGAFKQLQCLDPDGADGAFKINTCANDAQTMCEILEMVKVELKKDENFKDKCGGSSGGACGENNPDNPCSCKVCPYKQKVDHINQSYETYFNMFNPSNSNSVVPQQSQQLQQQQIQQQQQSQQQVQQQQQQQMQQQPQQQQQQPQQQQQNQQQGQQPQQQQQQGQLDYTTYIDPQLQMQQQLQMQQAAQQQYMQQTMDQQQQQQYYMQQYHLQQQQQQQQAQRYLMQQQYMQQQAQQQQQQHQQVAIQQQQQQNQQQNQQQNQQQQNQSPQNQQSLDFQNANNFIDFNSGLGFMNFPNINFGDMGFSAV", "length": 802, "header": "sp|O00841-1|CUDA_DICDI Isoform 1 of Putative transcriptional regulator cudA OS=Dictyostelium discoideum OX=44689 GN=cudA PE=1 SV=2 CANONICAL=O00841-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Analysis of the promoter of the cudA gene reveals novel mechanisms of Dictyostelium cell type differentiation.", "journal": "Development", "date": "2000", "authors": "Fukuzawa M, Williams J G", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "reference": [ { "type": "PubMed", "id": "10821768", "url": "https://glygen.org/publication/PubMed/10821768" } ] }, { "title": "Adenylyl cyclase A expression is tip-specific in Dictyostelium slugs and directs StatA nuclear translocation and CudA gene expression.", "journal": "Dev. Biol.", "date": "2001", "authors": "Verkerke-van Wijk I, Fukuzawa M, Devreotes P N, Schaap P", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "reference": [ { "type": "PubMed", "id": "11356026", "url": "https://glygen.org/publication/PubMed/11356026" } ] }, { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] }, { "title": "cudA: a Dictyostelium gene with pleiotropic effects on cellular differentiation and slug behaviour.", "journal": "Development (Cambridge, England)", "date": "1997-07", "authors": "Fukuzawa M, Hopper N, Williams J", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "reference": [ { "type": "PubMed", "id": "9226443", "url": "https://glygen.org/publication/PubMed/9226443" } ] } ], "pathway": [ { "id": "ddi:DDB_G0284465", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0284465", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "pmid": "" }, { "name": "receptor signaling pathway via STAT", "id": "GO:0097696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097696", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "pmid": "" }, { "name": "sporulation resulting in formation of a cellular spore", "id": "GO:0030435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030435", "evidence": [ { "database": "UniProtKB", "id": "O00841", "url": "https://www.uniprot.org/uniprot/O00841" } ], "pmid": "" }, { 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