{ "uniprot_canonical_ac": "O00141-1", "uniprot_ac": "O00141", "uniprot_id": "SGK1_HUMAN", "mass": { "chemical_mass": 48942.0, "monoisotopic_mass": 48942.0 }, "refseq": { "ac": "NP_001137148", "name": "serine/threonine-protein kinase Sgk1 isoform 2", "summary": "This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" }, "gene_names": [ { "name": "SGK1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/O00141", "id": "O00141" }, { "name": "DKFZp686H1615", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O00141", "id": "O00141" }, { "name": "SGK1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148", "id": "NP_001137148" }, { "name": "SGK", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148", "id": "NP_001137148" }, { "name": "SGK", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/O00141", "id": "O00141" } ], "protein_names": [ { "name": "Serine/threonine-protein kinase Sgk1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "O00141" }, { "name": "2.7.11.1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O00141" }, { "name": "Serum/glucocorticoid-regulated kinase 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "O00141" }, { "name": "serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148", "id": "NP_001137148" }, { "name": "serine/threonine-protein kinase Sgk1 isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148", "id": "NP_001137148" } ], "function": [ { "annotation": "Induction of SGK1 via glucocorticoid-influenced clinical outcome of triple-negative breast cancer patients.", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" }, { "database": "PubMed", "id": "37286891", "url": "https://glygen.org/publication/PubMed/37286891" } ] }, { "annotation": "Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation.", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" }, { "database": "PubMed", "id": "37343701", "url": "https://glygen.org/publication/PubMed/37343701" } ] }, { "annotation": "Proteomics on malignant pleural effusions reveals ERalpha loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" }, { "database": "PubMed", "id": "37854018", "url": "https://glygen.org/publication/PubMed/37854018" } ] }, { "annotation": "Role of Serum/Glucocorticoid-Regulated Kinase 1 (SGK1) in Immune and Inflammatory Diseases. Review article", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" }, { "database": "PubMed", "id": "37353719", "url": "https://glygen.org/publication/PubMed/37353719" } ] }, { "annotation": "Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in cellular stress response. Contributes to regulation of renal Na(+) retention, renal K(+) elimination, salt appetite, gastric acid secretion, intestinal Na(+)/H(+) exchange and nutrient transport, insulin-dependent salt sensitivity of blood pressure, salt sensitivity of peripheral glucose uptake, cardiac repolarization and memory consolidation. Up-regulates Na(+) channels: SCNN1A/ENAC, SCN5A and ASIC1/ACCN2, K(+) channels: KCNJ1/ROMK1, KCNA1-5, KCNQ1-5 and KCNE1, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channels: BSND, CLCN2 and CFTR, glutamate transporters: SLC1A3/EAAT1, SLC1A2 /EAAT2, SLC1A1/EAAT3, SLC1A6/EAAT4 and SLC1A7/EAAT5, amino acid transporters: SLC1A5/ASCT2, SLC38A1/SN1 and SLC6A19, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, glutamate receptor: GRIK2/GLUR6. Up-regulates carriers: SLC9A3/NHE3, SLC12A1/NKCC2, SLC12A3/NCC, SLC5A3/SMIT, SLC2A1/GLUT1, SLC5A1/SGLT1 and SLC15A2/PEPT2. Regulates enzymes: GSK3A/B, PMM2 and Na(+)/K(+) ATPase, and transcription factors: CTNNB1 and nuclear factor NF-kappa-B. Stimulates sodium transport into epithelial cells by enhancing the stability and expression of SCNN1A/ENAC. This is achieved by phosphorylating the NEDD4L ubiquitin E3 ligase, promoting its interaction with 14-3-3 proteins, thereby preventing it from binding to SCNN1A/ENAC and targeting it for degradation. Regulates store-operated Ca(+2) entry (SOCE) by stimulating ORAI1 and STIM1. Regulates KCNJ1/ROMK1 directly via its phosphorylation or indirectly via increased interaction with SLC9A3R2/NHERF2. Phosphorylates MDM2 and activates MDM2-dependent ubiquitination of p53/TP53. Phosphorylates MAPT/TAU and mediates microtubule depolymerization and neurite formation in hippocampal neurons. Phosphorylates SLC2A4/GLUT4 and up-regulates its activity. Phosphorylates APBB1/FE65 and promotes its localization to the nucleus. Phosphorylates MAPK1/ERK2 and activates it by enhancing its interaction with MAP2K1/MEK1 and MAP2K2/MEK2. Phosphorylates FBXW7 and plays an inhibitory role in the NOTCH1 signaling. Phosphorylates FOXO1 resulting in its relocalization from the nucleus to the cytoplasm. Phosphorylates FOXO3, promoting its exit from the nucleus and interference with FOXO3-dependent transcription. Phosphorylates BRAF and MAP3K3/MEKK3 and inhibits their activity. Phosphorylates SLC9A3/NHE3 in response to dexamethasone, resulting in its activation and increased localization at the cell membrane. Phosphorylates CREB1. Necessary for vascular remodeling during angiogenesis. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Isoform 2 exhibited a greater effect on cell plasma membrane expression of SCNN1A/ENAC and Na(+) transport than isoform 1.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141#function" }, { "database": "PubMed", "id": "16036218", "url": "https://glygen.org/publication/PubMed/16036218" }, { "database": "PubMed", "id": "12590200", "url": "https://glygen.org/publication/PubMed/12590200" }, { "database": "PubMed", "id": "12397388", "url": "https://glygen.org/publication/PubMed/12397388" }, { "database": "PubMed", "id": "20730100", "url": "https://glygen.org/publication/PubMed/20730100" }, { "database": "PubMed", "id": "15845389", "url": "https://glygen.org/publication/PubMed/15845389" }, { "database": "PubMed", "id": "15044175", "url": "https://glygen.org/publication/PubMed/15044175" }, { "database": "PubMed", "id": "18753299", "url": "https://glygen.org/publication/PubMed/18753299" }, { "database": "PubMed", "id": "14623317", "url": "https://glygen.org/publication/PubMed/14623317" }, { "database": "PubMed", "id": "15737648", "url": "https://glygen.org/publication/PubMed/15737648" }, { "database": "PubMed", "id": "17382906", "url": "https://glygen.org/publication/PubMed/17382906" }, { "database": "PubMed", "id": "15496163", "url": "https://glygen.org/publication/PubMed/15496163" }, { "database": "PubMed", "id": "19447520", "url": "https://glygen.org/publication/PubMed/19447520" }, { "database": "PubMed", "id": "12761204", "url": "https://glygen.org/publication/PubMed/12761204" }, { "database": "PubMed", "id": "12634932", "url": "https://glygen.org/publication/PubMed/12634932" }, { "database": "PubMed", "id": "15733869", "url": "https://glygen.org/publication/PubMed/15733869" }, { "database": "PubMed", "id": "16443776", "url": "https://glygen.org/publication/PubMed/16443776" }, { "database": "PubMed", "id": "18005662", "url": "https://glygen.org/publication/PubMed/18005662" }, { "database": "PubMed", "id": "15888551", "url": "https://glygen.org/publication/PubMed/15888551" }, { "database": "PubMed", "id": "15319523", "url": "https://glygen.org/publication/PubMed/15319523" }, { "database": "PubMed", "id": "19756449", "url": "https://glygen.org/publication/PubMed/19756449" }, { "database": "PubMed", "id": "20511718", "url": "https://glygen.org/publication/PubMed/20511718" }, { "database": "PubMed", "id": "14706641", "url": "https://glygen.org/publication/PubMed/14706641" }, { "database": "PubMed", "id": "15040001", "url": "https://glygen.org/publication/PubMed/15040001" }, { "database": "PubMed", "id": "16982696", "url": "https://glygen.org/publication/PubMed/16982696" }, { "database": "PubMed", "id": "11696533", "url": "https://glygen.org/publication/PubMed/11696533" }, { "database": "PubMed", "id": "21865597", "url": "https://glygen.org/publication/PubMed/21865597" }, { "database": "PubMed", "id": "11410590", "url": "https://glygen.org/publication/PubMed/11410590" }, { "database": "PubMed", "id": "15234985", "url": "https://glygen.org/publication/PubMed/15234985" }, { "database": "PubMed", "id": "11154281", "url": "https://glygen.org/publication/PubMed/11154281" }, { "database": "PubMed", "id": "12650886", "url": "https://glygen.org/publication/PubMed/12650886" }, { "database": "PubMed", "id": "18304449", "url": "https://glygen.org/publication/PubMed/18304449" }, { "database": "PubMed", "id": "12911626", "url": "https://glygen.org/publication/PubMed/12911626" } ] }, { "annotation": "This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009].", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" } ] }, { "annotation": "[SGK1 as a therapeutic target for central nervous system diseases].", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" }, { "database": "PubMed", "id": "37340653", "url": "https://glygen.org/publication/PubMed/37340653" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 127, "end_pos": 127, "sequence_org": "K", "sequence_mut": "M", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "15040001", "url": "https://glygen.org/publication/PubMed/15040001" }, { "database": "PubMed", "id": "11696533", "url": "https://glygen.org/publication/PubMed/11696533" }, { "database": "PubMed", "id": "12911626", "url": "https://glygen.org/publication/PubMed/12911626" } ] }, { "start_pos": 256, "end_pos": 256, "sequence_org": "T", "sequence_mut": "A", "comment": "Low activity.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" } ] }, { "start_pos": 256, "end_pos": 256, "sequence_org": "T", "sequence_mut": "D", "comment": "Low activity.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" } ] }, { "start_pos": 256, "end_pos": 256, "sequence_org": "T", "sequence_mut": "E", "comment": "Low activity.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" } ] }, { "start_pos": 298, "end_pos": 298, "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with NEDD4 and NEDD4L.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "11696533", "url": "https://glygen.org/publication/PubMed/11696533" } ] }, { "start_pos": 422, "end_pos": 422, "sequence_org": "S", "sequence_mut": "A", "comment": "Low activity.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "PubMed", "id": "15040001", "url": "https://glygen.org/publication/PubMed/15040001" }, { "database": "PubMed", "id": "11696533", "url": "https://glygen.org/publication/PubMed/11696533" }, { "database": "PubMed", "id": "12911626", "url": "https://glygen.org/publication/PubMed/12911626" } ] }, { "start_pos": 422, "end_pos": 422, "sequence_org": "S", "sequence_mut": "D", "comment": "10-fold activation.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "PubMed", "id": "15040001", "url": "https://glygen.org/publication/PubMed/15040001" }, { "database": "PubMed", "id": "11696533", "url": "https://glygen.org/publication/PubMed/11696533" }, { "database": "PubMed", "id": "12911626", "url": "https://glygen.org/publication/PubMed/12911626" } ] } ], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "97.67", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "97.65", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "96.75", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "93.24", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "90.88", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "96.15", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "99.1", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "88.66", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "96.98", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "98.84", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "96.65", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "96.05", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "94.26", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, hereditary", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, intestinal", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Urinary bladder cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ] } ] }, { "significant": "No", "trend": "down", "name": "Head and neck cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ] } ] }, { "significant": "No", "trend": "down", "name": "Lung cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1324", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "Nonsmall cell lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "alveolar cell carcinoma", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung neoplasm", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Breast cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1612", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "A thoracic cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, familial Male", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Thyroid cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:1781", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:1781", "recommended_name": { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." }, "synonyms": [ { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid gland cancer", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1781", "name": "thyroid neoplasm", "description": "" } ] } ] }, { "significant": "No", "trend": "down", "name": "Kidney cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:263", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:263", "recommended_name": { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney." }, "synonyms": [ { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant neoplasm of kidney except pelvis", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "malignant tumour of kidney", "description": "" }, { "id": "DOID:263", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:263", "name": "renal cancer", "description": "" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Liver cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:3571", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "hepatic neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant hepato-biliary neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant tumor of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "non-resectable primary hepatic malignant neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "primary liver cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "primary malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "resectable malignant neoplasm of the liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, not specified as primary or secondary", "description": "" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Uterine cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:363", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:363", "recommended_name": { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine cancer", "description": "A female reproductive organ cancer that is located_in the uterus." }, "synonyms": [ { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "CA - cancer of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "Tumour of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "malignant uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "neoplasm of uterus", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterine tumor", "description": "" }, { "id": "DOID:363", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:363", "name": "uterus neoplasm", "description": "" } ] } ] }, { "significant": "No", "trend": "down", "name": "Esophageal cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:5041", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:5041", "recommended_name": { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus." }, "synonyms": [ { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "Ca lower third oesophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "Ca middle third oesophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "esophagus cancer", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant neoplasm of distal third of esophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant neoplasm of lower third of oesophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant neoplasm of middle third of oesophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant neoplasm of proximal third of esophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant neoplasm of upper third esophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant tumor of Distal Third of esophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant tumor of Proximal Third of esophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant tumor of abdominal esophagus", "description": "" }, { "id": "DOID:5041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5041", "name": "malignant tumor of the middle Third of the esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophageal cancer", "description": "A primary or metastatic malignant neoplasm involving the esophagus." }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "cancer of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "cancer of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophageal cancer", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophageal cancer, somatic", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophageal carcinoma, somatic", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophageal squamous cell carcinoma, somatic", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophagus cancer", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant esophageal neoplasm", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant esophageal tumor", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant esophageal tumour", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant esophagus neoplasm", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant esophagus tumor", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of the esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of the oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant oesophagus neoplasm", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant oesophagus tumour", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of the esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of the oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "oesophagus cancer", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "Ca lower third esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "Ca lower third oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "Ca middle third esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "Ca middle third oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of distal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of distal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of lower third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of lower third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of middle third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of middle third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of proximal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of proximal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of upper third esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of upper third oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of abdominal esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of distal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of proximal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of the middle third of the esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of abdominal oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of distal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of proximal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of the middle third of the oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "Aerodigestive tract cancer, susceptibility to", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "Escc, susceptibility to", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "esophageal squamous cell carcinoma, susceptibility to", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "gastric cardia adenocarcinoma, susceptibility to", "description": "" }, { "id": "MIM:133239", "resource": "MIM", "url": "https://www.omim.org/entry/133239", "name": "Esophageal cancer", "description": "Esophageal cancer" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Colorectal cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:9256", "evidence": [ { "database": "BioXpress", "id": "O00141", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/O00141" } ], "disease": [ { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "large intestine cancer", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ] } ] } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "common_name": "Human" } ], "gene": [ { "name": "SGK1", "url": "https://www.uniprot.org/uniprot/O00141", "locus": { "chromosome": "6", "start_pos": 134169248, "end_pos": 134318112, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSG00000118515", "url": "https://www.ensembl.org/id/ENSG00000118515" } ] } } ], "crossref": [ { "id": "ENSG00000118515", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000118515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "2.7.11.1", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1&UniProtAcc=O00141", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd05602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "CHEMBL2343", "url": "https://www.ebi.ac.uk/chembldb/target/inspect/CHEMBL2343", "database": "ChEMBL", "categories": [ "Other" ] }, { "id": "SGK1", "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=SGK1", "database": "GeneCards", "categories": [ "Gene Annotation", "Organism-specific" ] }, { "id": "6446", "url": "https://www.ncbi.nlm.nih.gov/gene/6446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "10810", "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=10810", "database": "HGNC", "categories": [ "Organism-specific" ] }, { "id": "O00141", "url": "https://www.ebi.ac.uk/intact/interactors/id:O00141*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "hsa:6446", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:6446", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "602958", "url": "http://www.omim.org/entry/602958", "database": "MIM", "categories": [ "Other" ] }, { "id": "NX_O00141", "url": "https://www.nextprot.org/entry/NX_O00141", "database": "neXtProt", "categories": [ "Protein", "Organism-specific" ] }, { "id": "MNIVIRD", "url": "https://omabrowser.org/oma/group/MNIVIRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3028764at2759", "url": "http://www.orthodb.org/?query=3028764at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351:SF184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351:SF184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "2R5T", "url": "https://www.rcsb.org/structure/2R5T", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3HDM", "url": "https://www.rcsb.org/structure/3HDM", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "3HDN", "url": "https://www.rcsb.org/structure/3HDN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7PUE", "url": "https://www.rcsb.org/structure/7PUE", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00069", "url": "http://pfam.xfam.org/family/PF00069", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00433", "url": "http://pfam.xfam.org/family/PF00433", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "http://pfam.xfam.org/family/PF00787", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "O00141", "url": "https://pharos.nih.gov/targets/O00141", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR_O00141", "url": "http://purl.obolibrary.org/obo/PR_O00141", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-HSA-8986944", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8986944", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E9PJN2", "url": "https://www.uniprot.org/uniprot/E9PJN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PJN2-1", "url": "https://www.uniprot.org/uniprot/E9PJN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PP33", "url": "https://www.uniprot.org/uniprot/E9PP33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PP33-1", "url": "https://www.uniprot.org/uniprot/E9PP33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PR89", "url": "https://www.uniprot.org/uniprot/E9PR89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PR89-1", "url": "https://www.uniprot.org/uniprot/E9PR89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YCJ3", "url": "https://www.uniprot.org/uniprot/H0YCJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YCJ3-1", "url": "https://www.uniprot.org/uniprot/H0YCJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O00141-1", "url": "https://www.uniprot.org/uniprot/O00141-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O00141-2", "url": "https://www.uniprot.org/uniprot/O00141-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O00141-3", "url": "https://www.uniprot.org/uniprot/O00141-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O00141-4", "url": "https://www.uniprot.org/uniprot/O00141-4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O00141-5", "url": "https://www.uniprot.org/uniprot/O00141-5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7Z3I4", "url": "https://www.uniprot.org/uniprot/Q7Z3I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7Z3I4-1", "url": "https://www.uniprot.org/uniprot/Q7Z3I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 431, "header": "sp|O00141-1|SGK1_HUMAN Isoform 1 of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 CANONICAL=O00141-1" }, "isoforms": [ { "isoform_ac": "E9PJN2-1", "url": "", "sequence": { "sequence": "MVSVDKHQSPSLKYTGSSMVHIPPGEPDFESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPS", "length": 144, "header": "tr|E9PJN2-1|E9PJN2_HUMAN Computationally mapped isoform of Serum/glucocorticoid regulated kinase 1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=1 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134262124, "end_pos": 134173555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000461976.2", "url": "https://www.ensembl.org/id/ENST00000461976.2" }, { "database": "Ensembl Peptide", "id": "ENSP00000435577.1", "url": "https://www.ensembl.org/id/ENSP00000435577.1" } ] } }, { "isoform_ac": "E9PP33-1", "url": "", "sequence": { "sequence": "MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDF", "length": 60, "header": "tr|E9PP33-1|SGK1_HUMAN Computationally mapped isoform of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=1 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134317460, "end_pos": 134262038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000533224.1", "url": "https://www.ensembl.org/id/ENST00000533224.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000436470.1", "url": "https://www.ensembl.org/id/ENSP00000436470.1" } ] } }, { "isoform_ac": "E9PR89-1", "url": "", "sequence": { "sequence": "MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 387, "header": "tr|E9PR89-1|SGK1_HUMAN Computationally mapped isoform of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=1 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134174807, "end_pos": 134170271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000475719.6", "url": "https://www.ensembl.org/id/ENST00000475719.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000434302.1", "url": "https://www.ensembl.org/id/ENSP00000434302.1" } ] } }, { "isoform_ac": "H0YCJ3-1", "url": "", "sequence": { "sequence": "XPPGEPDFESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEILCKTSGQLTSP", "length": 55, "header": "tr|H0YCJ3-1|H0YCJ3_HUMAN Computationally mapped isoform of Serum/glucocorticoid regulated kinase 1 OS=Homo sapiens OX=9606 GN=SGK1 PE=4 SV=1 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134262059, "end_pos": 134215056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000460769.1", "url": "https://www.ensembl.org/id/ENST00000460769.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000431705.1", "url": "https://www.ensembl.org/id/ENSP00000431705.1" } ] } }, { "isoform_ac": "O00141-1", "url": "", "sequence": { "sequence": "MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 431, "header": "sp|O00141-1|SGK1_HUMAN Isoform 1 of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134174807, "end_pos": 134170271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000237305.12", "url": "https://www.ensembl.org/id/ENST00000237305.12" }, { "database": "Ensembl Peptide", "id": "ENSP00000237305.7", "url": "https://www.ensembl.org/id/ENSP00000237305.7" } ] } }, { "isoform_ac": "O00141-2", "url": "", "sequence": { "sequence": "MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDFESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 526, "header": "sp|O00141-2|SGK1_HUMAN Isoform 2 of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134317460, "end_pos": 134170271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367858.10", "url": "https://www.ensembl.org/id/ENST00000367858.10" }, { "database": "Ensembl Peptide", "id": "ENSP00000356832.5", "url": "https://www.ensembl.org/id/ENSP00000356832.5" } ] } }, { "isoform_ac": "O00141-3", "url": "", "sequence": { "sequence": "MGEMQGALARARLESLLRPRHKKRAEAQKRSESFLLSGLAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 445, "header": "sp|O00141-3|SGK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134175661, "end_pos": 134170271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000413996.7", "url": "https://www.ensembl.org/id/ENST00000413996.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000396242.3", "url": "https://www.ensembl.org/id/ENSP00000396242.3" } ] } }, { "isoform_ac": "O00141-4", "url": "", "sequence": { "sequence": "MKPSKRFFISPPSSTAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 421, "header": "sp|O00141-4|SGK1_HUMAN Isoform 4 of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134174632, "end_pos": 134170271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367857.9", "url": "https://www.ensembl.org/id/ENST00000367857.9" }, { "database": "Ensembl Peptide", "id": "ENSP00000356831.5", "url": "https://www.ensembl.org/id/ENSP00000356831.5" } ] } }, { "isoform_ac": "O00141-5", "url": "", "sequence": { "sequence": "MSSQSSSLSEACSREAYSSHNWALPPASRSNPQPAYPWATRRMKEEAIKPPLKAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL", "length": 459, "header": "sp|O00141-5|SGK1_HUMAN Isoform 5 of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134177822, "end_pos": 134170271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000528577.5", "url": "https://www.ensembl.org/id/ENST00000528577.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000434450.1", "url": "https://www.ensembl.org/id/ENSP00000434450.1" } ] } }, { "isoform_ac": "Q7Z3I4-1", "url": "", "sequence": { "sequence": "MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDFESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVSSCSLWIYSPGKILGLCFSCISARVYPKNNFLMHIYKASEEDLELWSLLAHYVIFLK", "length": 153, "header": "tr|Q7Z3I4-1|SGK1_HUMAN Computationally mapped isoform of Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=1 CANONICAL=O00141-1" }, "locus": { "chromosome": "6", "start_pos": 134317460, "end_pos": 134261759, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000524929.1", "url": "https://www.ensembl.org/id/ENST00000524929.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000435724.1", "url": "https://www.ensembl.org/id/ENSP00000435724.1" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 256, "end_pos": 256, "kinase_uniprot_canonical_ac": "O15530-1", "kinase_gene_name": "PDPK1", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "PubMed", "id": "10357815", "url": "https://glygen.org/publication/PubMed/10357815" }, { "database": "PubMed", "id": "25384981", "url": "https://glygen.org/publication/PubMed/25384981" }, { "database": "PubMed", "id": "15209375", "url": "https://glygen.org/publication/PubMed/15209375" } ], "site_lbl": "Thr256" }, { "start_pos": 256, "end_pos": 256, "kinase_uniprot_canonical_ac": "Q6A1A2-1", "kinase_gene_name": "PDPK2P", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" } ], "site_lbl": "Thr256" }, { "start_pos": 256, "end_pos": 256, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PDPK1", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" }, { "database": "PRO", "id": "O00141", "url": "http://purl.obolibrary.org/obo/O00141" }, { "database": "PubMed", "id": "10357815", "url": "https://glygen.org/publication/PubMed/10357815" }, { "database": "PubMed", "id": "19025518", "url": "https://glygen.org/publication/PubMed/19025518" }, { "database": "PubMed", "id": "19068477", "url": "https://glygen.org/publication/PubMed/19068477" }, { "database": "PubMed", "id": "21963429", "url": "https://glygen.org/publication/PubMed/21963429" }, { "database": "PubMed", "id": "23581296", "url": "https://glygen.org/publication/PubMed/23581296" }, { "database": "PubMed", "id": "29439494", "url": "https://glygen.org/publication/PubMed/29439494" }, { "database": "PubMed", "id": "29930759", "url": "https://glygen.org/publication/PubMed/29930759" }, { "database": "PubMed", "id": "30622697", "url": "https://glygen.org/publication/PubMed/30622697" } ], "site_lbl": "Thr256" }, { "start_pos": 369, "end_pos": 369, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "11096081", "url": "https://glygen.org/publication/PubMed/11096081" }, { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" } ], "site_lbl": "Thr369" }, { "start_pos": 377, "end_pos": 377, "kinase_uniprot_canonical_ac": "Q9HC98-1", "kinase_gene_name": "NEK6", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "12023960", "url": "https://glygen.org/publication/PubMed/12023960" }, { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" } ], "site_lbl": "Ser377" }, { "start_pos": 377, "end_pos": 377, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "12023960", "url": "https://glygen.org/publication/PubMed/12023960" } ], "site_lbl": "Ser377" }, { "start_pos": 397, "end_pos": 397, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "19369195", "url": "https://glygen.org/publication/PubMed/19369195" }, { "database": "PubMed", "id": "18691976", "url": "https://glygen.org/publication/PubMed/18691976" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" }, { "database": "PubMed", "id": "19068477", "url": "https://glygen.org/publication/PubMed/19068477" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "site_lbl": "Ser397" }, { "start_pos": 401, "end_pos": 401, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "19369195", "url": "https://glygen.org/publication/PubMed/19369195" }, { "database": "PubMed", "id": "18691976", "url": "https://glygen.org/publication/PubMed/18691976" }, { "database": "PubMed", "id": "19068477", "url": "https://glygen.org/publication/PubMed/19068477" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ], "site_lbl": "Ser401" }, { "start_pos": 422, "end_pos": 422, "kinase_uniprot_canonical_ac": "O00141-1", "kinase_gene_name": "SGK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "25384981", "url": "https://glygen.org/publication/PubMed/25384981" } ], "site_lbl": "Ser422" }, { "start_pos": 422, "end_pos": 422, "kinase_uniprot_canonical_ac": "O15530-1", "kinase_gene_name": "PDPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" } ], "site_lbl": "Ser422" }, { "start_pos": 422, "end_pos": 422, "kinase_uniprot_canonical_ac": "P42345-1", "kinase_gene_name": "MTOR", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "18570873", "url": "https://glygen.org/publication/PubMed/18570873" }, { "database": "PubMed", "id": "18925875", "url": "https://glygen.org/publication/PubMed/18925875" } ], "site_lbl": "Ser422" }, { "start_pos": 422, "end_pos": 422, "kinase_uniprot_canonical_ac": "Q9HC98-1", "kinase_gene_name": "NEK6", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "PubMed", "id": "12023960", "url": "https://glygen.org/publication/PubMed/12023960" }, { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" } ], "site_lbl": "Ser422" }, { "start_pos": 422, "end_pos": 422, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "PubMed", "id": "18925875", "url": "https://glygen.org/publication/PubMed/18925875" }, { "database": "PubMed", "id": "20338997", "url": "https://glygen.org/publication/PubMed/20338997" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "11096081", "url": "https://glygen.org/publication/PubMed/11096081" }, { "database": "PubMed", "id": "18570873", "url": "https://glygen.org/publication/PubMed/18570873" }, { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" }, { "database": "PRO", "id": "O00141", "url": "http://purl.obolibrary.org/obo/O00141" }, { "database": "PubMed", "id": "10357815", "url": "https://glygen.org/publication/PubMed/10357815" }, { "database": "PubMed", "id": "19025518", "url": "https://glygen.org/publication/PubMed/19025518" }, { "database": "PubMed", "id": "19584721", "url": "https://glygen.org/publication/PubMed/19584721" }, { "database": "PubMed", "id": "21963429", "url": "https://glygen.org/publication/PubMed/21963429" }, { "database": "PubMed", "id": "22842983", "url": "https://glygen.org/publication/PubMed/22842983" }, { "database": "PubMed", "id": "23581296", "url": "https://glygen.org/publication/PubMed/23581296" }, { "database": "PubMed", "id": "28106162", "url": "https://glygen.org/publication/PubMed/28106162" }, { "database": "PubMed", "id": "28916818", "url": "https://glygen.org/publication/PubMed/28916818" }, { "database": "PubMed", "id": "29439494", "url": "https://glygen.org/publication/PubMed/29439494" } ], "site_lbl": "Ser422" }, { "start_pos": 74, "end_pos": 74, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "19369195", "url": "https://glygen.org/publication/PubMed/19369195" }, { "database": "PubMed", "id": "18691976", "url": "https://glygen.org/publication/PubMed/18691976" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "site_lbl": "Ser74" }, { "start_pos": 78, "end_pos": 78, "kinase_uniprot_canonical_ac": "Q13164-1", "kinase_gene_name": "MAPK7", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "11254654", "url": "https://glygen.org/publication/PubMed/11254654" }, { "database": "PubMed", "id": "18691976", "url": "https://glygen.org/publication/PubMed/18691976" }, { "database": "phospho.ELM", "id": "O00141", "url": "http://phospho.elm.eu.org/byAccession/O00141.html" } ], "site_lbl": "Ser78" }, { "start_pos": 78, "end_pos": 78, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by MAPK7", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" }, { "database": "PubMed", "id": "11254654", "url": "https://glygen.org/publication/PubMed/11254654" }, { "database": "PubMed", "id": "15917303", "url": "https://glygen.org/publication/PubMed/15917303" }, { "database": "PubMed", "id": "28445935", "url": "https://glygen.org/publication/PubMed/28445935" } ], "site_lbl": "Ser78" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.", "journal": "The Biochemical journal", "date": "1999", "authors": "Kobayashi T, Cohen P", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" }, { "database": "iPTMnet", "id": "O00141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141-1" } ], "reference": [ { "type": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" } ] }, { "title": "The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience.", "journal": "Trends in neurosciences", "date": "1999", "authors": "O'Donovan KJ, Tourtellotte WG, Millbrandt J, Baraban JM", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10203854", "url": "https://glygen.org/publication/PubMed/10203854" } ] }, { "title": "Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.", "journal": "The EMBO journal", "date": "1999", "authors": "Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA", "evidence": [ { "database": "iPTMnet", "id": "O00141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141-1" } ], "reference": [ { "type": "PubMed", "id": "10357815", "url": "https://glygen.org/publication/PubMed/10357815" } ] }, { "title": "Staurosporine enhances cAMP-induced expression of neural-specific gene VGF and tyrosine hydroxylase.", "journal": "Neuroscience letters", "date": "1999", "authors": "Nagasaki K, Sasaki K, Maass N, Tsukada T, Hanzawa H, Yamaguchi K", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10381005", "url": "https://glygen.org/publication/PubMed/10381005" } ] }, { "title": "Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.", "journal": "Biochem. J.", "date": "1999", "authors": "Kobayashi T, Deak M, Morrice N, Cohen P", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "10548550", "url": "https://glygen.org/publication/PubMed/10548550" } ] }, { "title": "Identification of an acid-activated Cl(-) channel from human skeletal muscles.", "journal": "The American journal of physiology", "date": "1999", "authors": "Kawasaki M, Fukuma T, Yamauchi K, Sakamoto H, Marumo F, Sasaki S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "10564087", "url": "https://glygen.org/publication/PubMed/10564087" } ] }, { "title": "Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein.", "journal": "The Journal of biological chemistry", "date": "1999", "authors": "Sharp DA, Kratowicz SA, Sank MJ, George DL", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "10608892", "url": "https://glygen.org/publication/PubMed/10608892" } ] }, { "title": "Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Massari ME, Murre C", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10611221", "url": "https://glygen.org/publication/PubMed/10611221" } ] }, { "title": "Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1999", "authors": "Zhu J, Tseng YH, Kantor JD, Rhodes CJ, Zetter BR, Moyers JS, Kahn CR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10611312", "url": "https://glygen.org/publication/PubMed/10611312" } ] }, { "title": "Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits.", "journal": "The Biochemical journal", "date": "2000", "authors": "Farr TJ, Coddington-Lawson SJ, Snyder PM, McDonald FJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "10642508", "url": "https://glygen.org/publication/PubMed/10642508" } ] }, { "title": "Reciprocal Id expression and myelin gene regulation in Schwann cells.", "journal": "Molecular and cellular neurosciences", "date": "1999", "authors": "Thatikunta P, Qin W, Christy BA, Tennekoon GI, Rutkowski JL", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10656257", "url": "https://glygen.org/publication/PubMed/10656257" } ] }, { "title": "Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination.", "journal": "Kidney international", "date": "2000", "authors": "Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "10720933", "url": "https://glygen.org/publication/PubMed/10720933" } ] }, { "title": "Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Fang S, Jensen JP, Ludwig RL, Vousden KH, Weissman AM", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "10722742", "url": "https://glygen.org/publication/PubMed/10722742" } ] }, { "title": "A novel activation function for NAB proteins in EGR-dependent transcription of the luteinizing hormone beta gene.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Sevetson BR, Svaren J, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10734128", "url": "https://glygen.org/publication/PubMed/10734128" } ] }, { "title": "Molecular cloning, functional expression and chromosomal localization of an amiloride-sensitive Na(+) channel from human small intestine.", "journal": "FEBS letters", "date": "2000", "authors": "Schaefer L, Sakai H, Mattei M, Lazdunski M, Lingueglia E", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "10767424", "url": "https://glygen.org/publication/PubMed/10767424" } ] }, { "title": "Full promoter sequence of human early growth response factor-1 (Egr-1): demonstration of a fifth functional serum response element.", "journal": "DNA sequence : the journal of DNA sequencing and mapping", "date": "2000", "authors": "Schwachtgen JL, Campbell CJ, Braddock M", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10826704", "url": "https://glygen.org/publication/PubMed/10826704" } ] }, { "title": "PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.", "journal": "Cell", "date": "2000", "authors": "Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "10830164", "url": "https://glygen.org/publication/PubMed/10830164" } ] }, { "title": "Functional and structural analysis of ClC-K chloride channels involved in renal disease.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Waldegger S, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "10831588", "url": "https://glygen.org/publication/PubMed/10831588" } ] }, { "title": "CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals.", "journal": "Annual review of biochemistry", "date": "1999", "authors": "Shaywitz AJ, Greenberg ME", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10872467", "url": "https://glygen.org/publication/PubMed/10872467" } ] }, { "title": "VGF: a novel role for this neuronal and neuroendocrine polypeptide in the regulation of energy balance.", "journal": "Frontiers in neuroendocrinology", "date": "2000", "authors": "Salton SR, Ferri GL, Hahm S, Snyder SE, Wilson AJ, Possenti R, Levi A", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10882540", "url": "https://glygen.org/publication/PubMed/10882540" } ] }, { "title": "Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2000", "authors": "Lang F, Klingel K, Wagner C A, Stegen C, Warntges S, Friedrich B, Lanzendorfer M, Melzig J, Moschen I, Steuer S, Waldegger S, Sauter M, Paulmichl M, Gerke V, Risler T, Gamba G, Capasso G, Kandolf R, Hebert S C, Massry S G, Bro\u00ebr S", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "10884438", "url": "https://glygen.org/publication/PubMed/10884438" } ] }, { "title": "An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.", "journal": "Nature cell biology", "date": "2000", "authors": "Boyd SD, Tsai KY, Jacks T", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "10980695", "url": "https://glygen.org/publication/PubMed/10980695" } ] }, { "title": "The MDM2 RING-finger domain is required to promote p53 nuclear export.", "journal": "Nature cell biology", "date": "2000", "authors": "Geyer RK, Yu ZK, Maki CG", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "10980696", "url": "https://glygen.org/publication/PubMed/10980696" } ] }, { "title": "EGR1 target genes in prostate carcinoma cells identified by microarray analysis.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Svaren J, Ehrig T, Abdulkadir SA, Ehrengruber MU, Watson MA, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "10984481", "url": "https://glygen.org/publication/PubMed/10984481" } ] }, { "title": "The human transcriptional repressor protein NAB1: expression and biological activity.", "journal": "Biochimica et biophysica acta", "date": "2000", "authors": "Thiel G, Kaufmann K, Magin A, Lietz M, Bach K, Cramer M", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11018254", "url": "https://glygen.org/publication/PubMed/11018254" } ] }, { "title": "Regulation of Id gene expression during embryonic stem cell-derived hematopoietic differentiation.", "journal": "Biochemical and biophysical research communications", "date": "2000", "authors": "Nogueira MM, Mitjavila-Garcia MT, Le Pesteur F, Filippi MD, Vainchenker W, Dubart Kupperschmitt A, Sainteny F", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11027551", "url": "https://glygen.org/publication/PubMed/11027551" } ] }, { "title": "Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Perrotti N, He RA, Phillips SA, Haft CR, Taylor SI", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "11096081", "url": "https://glygen.org/publication/PubMed/11096081" } ] }, { "title": "Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).", "journal": "Molecular and cellular biology", "date": "2001", "authors": "Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "11154281", "url": "https://glygen.org/publication/PubMed/11154281" } ] }, { "title": "Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus.", "journal": "Neuron", "date": "2001", "authors": "Stobrawa SM, Breiderhoff T, Takamori S, Engel D, Schweizer M, Zdebik AA, Bosl MR, Ruether K, Jahn H, Draguhn A, Jahn R, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11182090", "url": "https://glygen.org/publication/PubMed/11182090" } ] }, { "title": "BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Hayashi M, Tapping RI, Chao TH, Lo JF, King CC, Yang Y, Lee JD", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141-1" } ], "reference": [ { "type": "PubMed", "id": "11254654", "url": "https://glygen.org/publication/PubMed/11254654" } ] }, { "title": "Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23.", "journal": "Cancer research", "date": "2001", "authors": "Tseng YH, Vicent D, Zhu J, Niu Y, Adeyinka A, Moyers JS, Watson PH, Kahn CR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11280768", "url": "https://glygen.org/publication/PubMed/11280768" } ] }, { "title": "ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1.", "journal": "Nature cell biology", "date": "2001", "authors": "Harada T, Morooka T, Ogawa S, Nishida E", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11331872", "url": "https://glygen.org/publication/PubMed/11331872" } ] }, { "title": "Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation.", "journal": "Neuron", "date": "2001", "authors": "Steward O, Worley PF", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11343657", "url": "https://glygen.org/publication/PubMed/11343657" } ] }, { "title": "Cyclin a-CDK phosphorylation regulates MDM2 protein interactions.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Zhang T, Prives C", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "11359766", "url": "https://glygen.org/publication/PubMed/11359766" } ] }, { "title": "Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Zhang BH, Tang ED, Zhu T, Greenberg ME, Vojtek AB, Guan KL", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "11410590", "url": "https://glygen.org/publication/PubMed/11410590" } ] }, { "title": "A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001", "authors": "Mayo LD, Donner DB", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "11504915", "url": "https://glygen.org/publication/PubMed/11504915" } ] }, { "title": "Frequent and early loss of the EGR1 corepressor NAB2 in human prostate carcinoma.", "journal": "Human pathology", "date": "2001", "authors": "Abdulkadir SA, Carbone JM, Naughton CK, Humphrey PA, Catalona WJ, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11567222", "url": "https://glygen.org/publication/PubMed/11567222" } ] }, { "title": "Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2001", "authors": "Voilley N, de Weille J, Mamet J, Lazdunski M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11588175", "url": "https://glygen.org/publication/PubMed/11588175" } ] }, { "title": "Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure.", "journal": "Nature genetics", "date": "2001", "authors": "Birkenhager R, Otto E, Schurmann MJ, Vollmer M, Ruf EM, Maier-Lutz I, Beekmann F, Fekete A, Omran H, Feldmann D, Milford DV, Jeck N, Konrad M, Landau D, Knoers NV, Antignac C, Sudbrak R, Kispert A, Hildebrandt F", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11687798", "url": "https://glygen.org/publication/PubMed/11687798" } ] }, { "title": "Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Snyder PM, Olson DR, Thomas BC", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "11696533", "url": "https://glygen.org/publication/PubMed/11696533" } ] }, { "title": "Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.", "journal": "Nature", "date": "2001", "authors": "Estevez R, Boettger T, Stein V, Birkenhager R, Otto E, Hildebrandt F, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11734858", "url": "https://glygen.org/publication/PubMed/11734858" } ] }, { "title": "NGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interaction.", "journal": "FEBS letters", "date": "2002", "authors": "Mandolesi G, Gargano S, Pennuto M, Illi B, Molfetta R, Soucek L, Mosca L, Levi A, Jucker R, Nasi S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11755530", "url": "https://glygen.org/publication/PubMed/11755530" } ] }, { "title": "Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB.", "journal": "Oncogene", "date": "2002", "authors": "Murga C, Zohar M, Teramoto H, Gutkind JS", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "11803464", "url": "https://glygen.org/publication/PubMed/11803464" } ] }, { "title": "The regulation and function of the Id proteins in lymphocyte development.", "journal": "Oncogene", "date": "2001", "authors": "Rivera R, Murre C", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11840323", "url": "https://glygen.org/publication/PubMed/11840323" } ] }, { "title": "A calcium-activated chloride channel (HCLCA1) is strongly related to IL-9 expression and mucus production in bronchial epithelium of patients with asthma.", "journal": "The Journal of allergy and clinical immunology", "date": "2002", "authors": "Toda M, Tulic MK, Levitt RC, Hamid Q", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11842292", "url": "https://glygen.org/publication/PubMed/11842292" } ] }, { "title": "The vitelliform macular dystrophy protein defines a new family of chloride channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2002", "authors": "Sun H, Tsunenari T, Yau KW, Nathans J", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11904445", "url": "https://glygen.org/publication/PubMed/11904445" } ] }, { "title": "Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization.", "journal": "Nature", "date": "2002", "authors": "Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, Gu W", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "11923872", "url": "https://glygen.org/publication/PubMed/11923872" } ] }, { "title": "Increased expression of the human Ca2+-activated Cl- channel 1 (CaCC1) gene in the asthmatic airway.", "journal": "American journal of respiratory and critical care medicine", "date": "2002", "authors": "Hoshino M, Morita S, Iwashita H, Sagiya Y, Nagi T, Nakanishi A, Ashida Y, Nishimura O, Fujisawa Y, Fujino M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "11956057", "url": "https://glygen.org/publication/PubMed/11956057" } ] }, { "title": "The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway.", "journal": "The Journal of cell biology", "date": "2002", "authors": "Ward Y, Yap SF, Ravichandran V, Matsumura F, Ito M, Spinelli B, Kelly K", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "11956230", "url": "https://glygen.org/publication/PubMed/11956230" } ] }, { "title": "Cyclin G recruits PP2A to dephosphorylate Mdm2.", "journal": "Molecular cell", "date": "2002", "authors": "Okamoto K, Li H, Jensen MR, Zhang T, Taya Y, Thorgeirsson SS, Prives C", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "11983168", "url": "https://glygen.org/publication/PubMed/11983168" } ] }, { "title": "Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Lizcano JM, Deak M, Morrice N, Kieloch A, Hastie CJ, Dong L, Schutkowski M, Reimer U, Alessi DR", "evidence": [ { "database": "iPTMnet", "id": "O00141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141-1" } ], "reference": [ { "type": "PubMed", "id": "12023960", "url": "https://glygen.org/publication/PubMed/12023960" } ] }, { "title": "Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B.", "journal": "Molecular and cellular biology", "date": "2002", "authors": "Scheid MP, Marignani PA, Woodgett JR", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "12167717", "url": "https://glygen.org/publication/PubMed/12167717" } ] }, { "title": "Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors.", "journal": "The Journal of clinical investigation", "date": "2002", "authors": "Ugawa S, Ueda T, Ishida Y, Nishigaki M, Shibata Y, Shimada S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "12393854", "url": "https://glygen.org/publication/PubMed/12393854" } ] }, { "title": "K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK.", "journal": "Pflugers Archiv : European journal of physiology", "date": "2002", "authors": "Gamper N, Fillon S, Feng Y, Friedrich B, Lang PA, Henke G, Huber SM, Kobayashi T, Cohen P, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12397388", "url": "https://glygen.org/publication/PubMed/12397388" } ] }, { "title": "Corepressor-dependent silencing of chromosomal regions encoding neuronal genes.", "journal": "Science (New York, N.Y.)", "date": "2002", "authors": "Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze SH, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "12399542", "url": "https://glygen.org/publication/PubMed/12399542" } ] }, { "title": "Synthesis of serotonin by a second tryptophan hydroxylase isoform.", "journal": "Science (New York, N.Y.)", "date": "2003", "authors": "Walther DJ, Peter JU, Bashammakh S, Hortnagl H, Voits M, Fink H, Bader M", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "12511643", "url": "https://glygen.org/publication/PubMed/12511643" } ] }, { "title": "Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms.", "journal": "Kidney & blood pressure research", "date": "2002", "authors": "Henke Guido, Setiawan Iwan, B\u00f6hmer Christoph, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12590200", "url": "https://glygen.org/publication/PubMed/12590200" } ] }, { "title": "Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domain.", "journal": "Mol. Biol. Cell", "date": "2003", "authors": "Maiyar Anita C, Leong Meredith L L, Firestone Gary L", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12631736", "url": "https://glygen.org/publication/PubMed/12631736" } ] }, { "title": "Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.", "journal": "Pflugers Archiv : European journal of physiology", "date": "2003-02", "authors": "Embark Hamdy M, B\u00f6hmer Christoph, Vallon Volker, Luft Friedrich, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12634932", "url": "https://glygen.org/publication/PubMed/12634932" } ] }, { "title": "Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity.", "journal": "Cell. Physiol. Biochem.", "date": "2003", "authors": "Firestone Gary L, Giampaolo Jennifer R, O'Keeffe Bridget A", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12649597", "url": "https://glygen.org/publication/PubMed/12649597" } ] }, { "title": "Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A.", "journal": "Cardiovascular research", "date": "2003-03-15", "authors": "Boehmer Christoph, Wilhelm Viktoria, Palmada Monica, Wallisch Sabine, Henke Guido, Brinkmeier Heinrich, Cohen Philip, Pieske Burkert, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12650886", "url": "https://glygen.org/publication/PubMed/12650886" } ] }, { "title": "Inhibition of mitogen-activated kinase kinase kinase 3 activity through phosphorylation by the serum- and glucocorticoid-induced kinase 1.", "journal": "Journal of biochemistry", "date": "2003", "authors": "Chun J, Kwon T, Kim DJ, Park I, Chung G, Lee EJ, Hong SK, Chang SI, Kim HY, Kang SS", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12761204", "url": "https://glygen.org/publication/PubMed/12761204" } ] }, { "title": "Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin.", "journal": "Journal of cellular physiology", "date": "2003", "authors": "Borgatti P, Martelli AM, Tabellini G, Bellacosa A, Capitani S, Neri LM", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "12767043", "url": "https://glygen.org/publication/PubMed/12767043" } ] }, { "title": "Structure-function analysis of the bestrophin family of anion channels.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Tsunenari T, Sun H, Williams J, Cahill H, Smallwood P, Yau KW, Nathans J", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "12907679", "url": "https://glygen.org/publication/PubMed/12907679" } ] }, { "title": "Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B.", "journal": "Journal of neurochemistry", "date": "2003", "authors": "Boehmer C, Henke G, Schniepp R, Palmada M, Rothstein JD, Broer S, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "12911626", "url": "https://glygen.org/publication/PubMed/12911626" } ] }, { "title": "NGF induces the expression of the VGF gene through a cAMP response element.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "1992", "authors": "Hawley RJ, Scheibe RJ, Wagner JA", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "1377233", "url": "https://glygen.org/publication/PubMed/1377233" } ] }, { "title": "The skeletal muscle chloride channel in dominant and recessive human myotonia.", "journal": "Science (New York, N.Y.)", "date": "1992", "authors": "Koch MC, Steinmeyer K, Lorenz C, Ricker K, Wolf F, Otto M, Zoll B, Lehmann-Horn F, Grzeschik KH, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "1379744", "url": "https://glygen.org/publication/PubMed/1379744" } ] }, { "title": "HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2003", "authors": "Linares LK, Hengstermann A, Ciechanover A, Muller S, Scheffner M", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "14507994", "url": "https://glygen.org/publication/PubMed/14507994" } ] }, { "title": "Local regulation of fat metabolism in peripheral nerves.", "journal": "Genes & development", "date": "2003", "authors": "Verheijen MH, Chrast R, Burrola P, Lemke G", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "14522948", "url": "https://glygen.org/publication/PubMed/14522948" } ] }, { "title": "Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis.", "journal": "Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research", "date": "2003", "authors": "Frattini A, Pangrazio A, Susani L, Sobacchi C, Mirolo M, Abinun M, Andolina M, Flanagan A, Horwitz EM, Mihci E, Notarangelo LD, Ramenghi U, Teti A, Van Hove J, Vujic D, Young T, Albertini A, Orchard PJ, Vezzoni P, Villa A", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "14584882", "url": "https://glygen.org/publication/PubMed/14584882" } ] }, { "title": "Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2003", "authors": "Cote F, Thevenot E, Fligny C, Fromes Y, Darmon M, Ripoche MA, Bayard E, Hanoun N, Saurini F, Lechat P, Dandolo L, Hamon M, Mallet J, Vodjdani G", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "14597720", "url": "https://glygen.org/publication/PubMed/14597720" } ] }, { "title": "Molecular requirements for the regulation of the renal outer medullary K(+) channel ROMK1 by the serum- and glucocorticoid-inducible kinase SGK1.", "journal": "Biochemical and biophysical research communications", "date": "2003-11-21", "authors": "Palmada Monica, Embark Hamdy M, Yun Chris, B\u00f6hmer Christoph, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "14623317", "url": "https://glygen.org/publication/PubMed/14623317" } ] }, { "title": "A new sperm-specific Na+/H+ exchanger required for sperm motility and fertility.", "journal": "Nature cell biology", "date": "2003", "authors": "Wang D, King SM, Quill TA, Doolittle LK, Garbers DL", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "14634667", "url": "https://glygen.org/publication/PubMed/14634667" } ] }, { "title": "Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B.", "journal": "Biochemical and biophysical research communications", "date": "2004-01-23", "authors": "Boehmer Christoph, Embark Hamdy M, Bauer Anna, Palmada Monica, Yun Chris H, Weinman Edward J, Endou Hitoshi, Cohen Philip, Lahme Sven, Bichler Karl-Horst, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "14706641", "url": "https://glygen.org/publication/PubMed/14706641" } ] }, { "title": "Muscarinic acetylcholine receptor stimulation induces expression of the activity-regulated cytoskeleton-associated gene (ARC).", "journal": "Brain research. Molecular brain research", "date": "2004", "authors": "Teber I, Kohling R, Speckmann EJ, Barnekow A, Kremerskothen J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "14969744", "url": "https://glygen.org/publication/PubMed/14969744" } ] }, { "title": "A novel human Cl(-) channel family related to Drosophila flightless locus.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Suzuki M, Mizuno A", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15010458", "url": "https://glygen.org/publication/PubMed/15010458" } ] }, { "title": "Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1.", "journal": "Journal of cellular physiology", "date": "2004", "authors": "Henke G, Maier G, Wallisch S, Boehmer C, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15040001", "url": "https://glygen.org/publication/PubMed/15040001" } ] }, { "title": "Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4-2 and by serum- and glucocorticoid-dependent kinase 1.", "journal": "American journal of physiology. Gastrointestinal and liver physiology", "date": "2004", "authors": "Palmada M, Dieter M, Speil A, Bohmer C, Mack AF, Wagner HJ, Klingel K, Kandolf R, Murer H, Biber J, Closs EI, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15044175", "url": "https://glygen.org/publication/PubMed/15044175" } ] }, { "title": "Salt wasting and deafness resulting from mutations in two chloride channels.", "journal": "The New England journal of medicine", "date": "2004", "authors": "Schlingmann KP, Konrad M, Jeck N, Waldegger P, Reinalter SC, Holder M, Seyberth HW, Waldegger S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15044642", "url": "https://glygen.org/publication/PubMed/15044642" } ] }, { "title": "A dynamic role of HAUSP in the p53-Mdm2 pathway.", "journal": "Molecular cell", "date": "2004", "authors": "Li M, Brooks CL, Kon N, Gu W", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "15053880", "url": "https://glygen.org/publication/PubMed/15053880" } ] }, { "title": "Rho kinase regulates schwann cell myelination and formation of associated axonal domains.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2004", "authors": "Melendez-Vasquez CV, Einheber S, Salzer JL", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15102911", "url": "https://glygen.org/publication/PubMed/15102911" } ] }, { "title": "CLIC-2 modulates cardiac ryanodine receptor Ca2+ release channels.", "journal": "The international journal of biochemistry & cell biology", "date": "2004", "authors": "Board PG, Coggan M, Watson S, Gage PW, Dulhunty AF", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15147738", "url": "https://glygen.org/publication/PubMed/15147738" } ] }, { "title": "Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2004", "authors": "Yamauchi J, Chan JR, Shooter EM", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15161978", "url": "https://glygen.org/publication/PubMed/15161978" } ] }, { "title": "PDK1, the master regulator of AGC kinase signal transduction.", "journal": "Seminars in cell & developmental biology", "date": "2004", "authors": "Mora A, Komander D, van Aalten DM, Alessi DR", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "15209375", "url": "https://glygen.org/publication/PubMed/15209375" } ] }, { "title": "A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit.", "journal": "The Journal of biological chemistry", "date": "2004-09-10", "authors": "Diakov Alexei, Korbmacher Christoph", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15234985", "url": "https://glygen.org/publication/PubMed/15234985" } ] }, { "title": "Association of the hCLCA1 gene with childhood and adult asthma.", "journal": "Genes and immunity", "date": "2004", "authors": "Kamada F, Suzuki Y, Shao C, Tamari M, Hasegawa K, Hirota T, Shimizu M, Takahashi N, Mao XQ, Doi S, Fujiwara H, Miyatake A, Fujita K, Chiba Y, Aoki Y, Kure S, Tamura G, Shirakawa T, Matsubara Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15318163", "url": "https://glygen.org/publication/PubMed/15318163" } ] }, { "title": "Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes.", "journal": "Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology", "date": "2004", "authors": "Embark Hamdy M, Setiawan Iwan, Poppendieck Susanne, van de Graaf Stan F J, Boehmer Christoph, Palmada Monica, Wieder Thomas, Gerstberger Ruediger, Cohen Philip, Yun C Chris, Bindels Ren\u00e9 J M, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15319523", "url": "https://glygen.org/publication/PubMed/15319523" } ] }, { "title": "The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation.", "journal": "Cell", "date": "1992", "authors": "Momand J, Zambetti GP, Olson DC, George D, Levine AJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "1535557", "url": "https://glygen.org/publication/PubMed/1535557" } ] }, { "title": "Egr-1 is activated by 17beta-estradiol in MCF-7 cells by mitogen-activated protein kinase-dependent phosphorylation of ELK-1.", "journal": "Journal of cellular biochemistry", "date": "2004", "authors": "Chen CC, Lee WR, Safe S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15449318", "url": "https://glygen.org/publication/PubMed/15449318" } ] }, { "title": "Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases.", "journal": "Kidney international", "date": "2004", "authors": "Embark HM, Bohmer C, Palmada M, Rajamanickam J, Wyatt AW, Wallisch S, Capasso G, Waldegger P, Seyberth HW, Waldegger S, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15496163", "url": "https://glygen.org/publication/PubMed/15496163" } ] }, { "title": "ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Hara-Chikuma M, Yang B, Sonawane ND, Sasaki S, Uchida S, Verkman AS", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15504734", "url": "https://glygen.org/publication/PubMed/15504734" } ] }, { "title": "NPT4, a new microsomal phosphate transporter: mutation analysis in glycogen storage disease type Ic.", "journal": "Journal of inherited metabolic disease", "date": "2004", "authors": "Melis D, Havelaar AC, Verbeek E, Smit GP, Benedetti A, Mancini GM, Verheijen F", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15505377", "url": "https://glygen.org/publication/PubMed/15505377" } ] }, { "title": "Ternary complex factor-serum response factor complex-regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Vickers ER, Kasza A, Kurnaz IA, Seifert A, Zeef LA, O'donnell A, Hayes A, Sharrocks AD", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15542842", "url": "https://glygen.org/publication/PubMed/15542842" } ] }, { "title": "Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Zhou R, Snyder PM", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15576372", "url": "https://glygen.org/publication/PubMed/15576372" } ] }, { "title": "Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions.", "journal": "Cell", "date": "2004", "authors": "Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM, Yochum GS, Boss JM, McWeeney S, Dunn JJ, Mandel G, Goodman RH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15620361", "url": "https://glygen.org/publication/PubMed/15620361" } ] }, { "title": "Regulatory elements in the promoter region of vgf, a nerve growth factor-inducible gene.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1992", "authors": "Possenti R, Di Rocco G, Nasi S, Levi A", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "1570299", "url": "https://glygen.org/publication/PubMed/1570299" } ] }, { "title": "Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.", "journal": "Science (New York, N.Y.)", "date": "2005", "authors": "Sarbassov DD, Guertin DA, Ali SM, Sabatini DM", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "15718470", "url": "https://glygen.org/publication/PubMed/15718470" } ] }, { "title": "Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB.", "journal": "FEBS letters", "date": "2005", "authors": "David S, Kalb RG", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15733869", "url": "https://glygen.org/publication/PubMed/15733869" } ] }, { "title": "Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Boehmer C, Rajamanickam J, Schniepp R, Kohler K, Wulff P, Kuhl D, Palmada M, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15737648", "url": "https://glygen.org/publication/PubMed/15737648" } ] }, { "title": "Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2005", "authors": "Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "15788536", "url": "https://glygen.org/publication/PubMed/15788536" } ] }, { "title": "Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination.", "journal": "Journal of neurochemistry", "date": "2005", "authors": "Leblanc SE, Srinivasan R, Ferri C, Mager GM, Gillian-Daniel AL, Wrabetz L, Svaren J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15836632", "url": "https://glygen.org/publication/PubMed/15836632" } ] }, { "title": "The serine/threonine kinases SGK1, 3 and PKB stimulate the amino acid transporter ASCT2.", "journal": "Biochemical and biophysical research communications", "date": "2005-05-27", "authors": "Palmada Monica, Speil Andreas, Jeyaraj Sankarganesh, B\u00f6hmer Christoph, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15845389", "url": "https://glygen.org/publication/PubMed/15845389" } ] }, { "title": "SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability.", "journal": "Nature neuroscience", "date": "2005", "authors": "Ramanan N, Shen Y, Sarsfield S, Lemberger T, Schutz G, Linden DJ, Ginty DD", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "15880109", "url": "https://glygen.org/publication/PubMed/15880109" } ] }, { "title": "Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1.", "journal": "American journal of physiology. Cell physiology", "date": "2005", "authors": "Wang D, Sun H, Lang F, Yun CC", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "15888551", "url": "https://glygen.org/publication/PubMed/15888551" } ] }, { "title": "A recently identified member of the glutathione transferase structural family modifies cardiac RyR2 substate activity, coupled gating and activation by Ca2+ and ATP.", "journal": "The Biochemical journal", "date": "2005", "authors": "Dulhunty AF, Pouliquin P, Coggan M, Gage PW, Board PG", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15916532", "url": "https://glygen.org/publication/PubMed/15916532" } ] }, { "title": "Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.", "journal": "Molecular cell", "date": "2005", "authors": "Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, Dirks RW, Jochemsen AG", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "15916963", "url": "https://glygen.org/publication/PubMed/15916963" } ] }, { "title": "IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway.", "journal": "American journal of physiology. Cell physiology", "date": "2005", "authors": "Meng F, Yamagiwa Y, Taffetani S, Han J, Patel T", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "15917303", "url": "https://glygen.org/publication/PubMed/15917303" } ] }, { "title": "hCLCA1 and mCLCA3 are secreted non-integral membrane proteins and therefore are not ion channels.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Gibson A, Lewis AP, Affleck K, Aitken AJ, Meldrum E, Thompson N", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "15919655", "url": "https://glygen.org/publication/PubMed/15919655" } ] }, { "title": "Id family of helix-loop-helix proteins in cancer.", "journal": "Nature reviews. Cancer", "date": "2005", "authors": "Perk J, Iavarone A, Benezra R", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16034366", "url": "https://glygen.org/publication/PubMed/16034366" } ] }, { "title": "Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3.", "journal": "Biochemical and biophysical research communications", "date": "2005-09-02", "authors": "Shojaiefard Manzar, Christie David L, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "16036218", "url": "https://glygen.org/publication/PubMed/16036218" } ] }, { "title": "Nab proteins are essential for peripheral nervous system myelination.", "journal": "Nature neuroscience", "date": "2005", "authors": "Le N, Nagarajan R, Wang JY, Svaren J, LaPash C, Araki T, Schmidt RE, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16136673", "url": "https://glygen.org/publication/PubMed/16136673" } ] }, { "title": "Amplification of a gene encoding a p53-associated protein in human sarcomas.", "journal": "Nature", "date": "1992", "authors": "Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "1614537", "url": "https://glygen.org/publication/PubMed/1614537" } ] }, { "title": "ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.", "journal": "The EMBO journal", "date": "2005", "authors": "Chen L, Gilkes DM, Pan Y, Lane WS, Chen J", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "16163388", "url": "https://glygen.org/publication/PubMed/16163388" } ] }, { "title": "BMP enhances transcriptional responses to NGF during PC12 cell differentiation.", "journal": "Neurochemical research", "date": "2005", "authors": "Lonn P, Zaia K, Israelsson C, Althini S, Usoskin D, Kylberg A, Ebendal T", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16187211", "url": "https://glygen.org/publication/PubMed/16187211" } ] }, { "title": "The Drosophila tweety family: molecular candidates for large-conductance Ca2+-activated Cl- channels.", "journal": "Experimental physiology", "date": "2006", "authors": "Suzuki M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "16219661", "url": "https://glygen.org/publication/PubMed/16219661" } ] }, { "title": "A prohormone convertase cleavage site within a predicted alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Garcia AL, Han SK, Janssen WG, Khaing ZZ, Ito T, Glucksman MJ, Benson DL, Salton SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16221685", "url": "https://glygen.org/publication/PubMed/16221685" } ] }, { "title": "Egr-1 induces the expression of its corepressor nab2 by activation of the nab2 promoter thereby establishing a negative feedback loop.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Kumbrink J, Gerlinger M, Johnson JP", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16260776", "url": "https://glygen.org/publication/PubMed/16260776" } ] }, { "title": "The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Li L, Carter J, Gao X, Whitehead J, Tourtellotte WG", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16287845", "url": "https://glygen.org/publication/PubMed/16287845" } ] }, { "title": "Immediate-early gene-encoded protein Arc is associated with synaptic delivery of GluR4-containing AMPA receptors during in vitro classical conditioning.", "journal": "Journal of neurophysiology", "date": "2006", "authors": "Mokin M, Lindahl JS, Keifer J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16339507", "url": "https://glygen.org/publication/PubMed/16339507" } ] }, { "title": "Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway.", "journal": "PLoS biology", "date": "2006", "authors": "Hu M, Gu L, Li M, Jeffrey PD, Gu W, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "16402859", "url": "https://glygen.org/publication/PubMed/16402859" } ] }, { "title": "Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2006", "authors": "Nakamura K, Sugawara Y, Sawabe K, Ohashi A, Tsurui H, Xiu Y, Ohtsuji M, Lin QS, Nishimura H, Hasegawa H, Hirose S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16407550", "url": "https://glygen.org/publication/PubMed/16407550" } ] }, { "title": "SGK1 kinase upregulates GLUT1 activity and plasma membrane expression.", "journal": "Diabetes", "date": "2006-02", "authors": "Palmada Monica, Boehmer Christoph, Akel Ahmad, Rajamanickam Jeyaganesh, Jeyaraj Sankarganesh, Keller Konrad, Lang Florian", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "16443776", "url": "https://glygen.org/publication/PubMed/16443776" } ] }, { "title": "Sgk kinases and their role in epithelial transport.", "journal": "Annu. Rev. Physiol.", "date": "2006", "authors": "Loffing J, Flores SY, Staub O", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "16460280", "url": "https://glygen.org/publication/PubMed/16460280" } ] }, { "title": "Molecular recognition of p53 and MDM2 by USP7/HAUSP.", "journal": "Nature structural & molecular biology", "date": "2006", "authors": "Sheng Y, Saridakis V, Sarkari F, Duan S, Wu T, Arrowsmith CH, Frappier L", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "16474402", "url": "https://glygen.org/publication/PubMed/16474402" } ] }, { "title": "Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.", "journal": "Science (New York, N.Y.)", "date": "2006", "authors": "Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16484497", "url": "https://glygen.org/publication/PubMed/16484497" } ] }, { "title": "NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Srinivasan R, Mager GM, Ward RM, Mayer J, Svaren J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16574654", "url": "https://glygen.org/publication/PubMed/16574654" } ] }, { "title": "AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc.", "journal": "Nature neuroscience", "date": "2006", "authors": "Rao VR, Pintchovski SA, Chin J, Peebles CL, Mitra S, Finkbeiner S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "16732277", "url": "https://glygen.org/publication/PubMed/16732277" } ] }, { "title": "Mutations in OSTM1 (grey lethal) define a particularly severe form of autosomal recessive osteopetrosis with neural involvement.", "journal": "Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research", "date": "2006", "authors": "Pangrazio A, Poliani PL, Megarbane A, Lefranc G, Lanino E, Di Rocco M, Rucci F, Lucchini F, Ravanini M, Facchetti F, Abinun M, Vezzoni P, Villa A, Frattini A", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "16813530", "url": "https://glygen.org/publication/PubMed/16813530" } ] }, { "title": "Critical role for Daxx in regulating Mdm2.", "journal": "Nature cell biology", "date": "2006", "authors": "Tang J, Qu LK, Zhang J, Wang W, Michaelson JS, Degenhardt YY, El-Deiry WS, Yang X", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "16845383", "url": "https://glygen.org/publication/PubMed/16845383" } ] }, { "title": "Barttin modulates trafficking and function of ClC-K channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2006", "authors": "Scholl U, Hebeisen S, Janssen AG, Muller-Newen G, Alekov A, Fahlke C", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "16849430", "url": "https://glygen.org/publication/PubMed/16849430" } ] }, { "title": "Cloning of a novel human NHEDC1 (Na+/H+ exchanger like domain containing 1) gene expressed specifically in testis.", "journal": "Molecular biology reports", "date": "2006", "authors": "Ye G, Chen C, Han D, Xiong X, Kong Y, Wan B, Yu L", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "16850186", "url": "https://glygen.org/publication/PubMed/16850186" } ] }, { "title": "Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau.", "journal": "Molecular and cellular biology", "date": "2006", "authors": "Yang YC, Lin CH, Lee EH", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "16982696", "url": "https://glygen.org/publication/PubMed/16982696" } ] }, { "title": "Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories.", "journal": "Neuron", "date": "2006", "authors": "Plath N, Ohana O, Dammermann B, Errington ML, Schmitz D, Gross C, Mao X, Engelsberg A, Mahlke C, Welzl H, Kobalz U, Stawrakakis A, Fernandez E, Waltereit R, Bick-Sander A, Therstappen E, Cooke SF, Blanquet V, Wurst W, Salmen B, Bosl MR, Lipp HP, Grant SG, Bliss TV, Wolfer DP, Kuhl D", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "17088210", "url": "https://glygen.org/publication/PubMed/17088210" } ] }, { "title": "Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking.", "journal": "Neuron", "date": "2006", "authors": "Chowdhury S, Shepherd JD, Okuno H, Lyford G, Petralia RS, Plath N, Kuhl D, Huganir RL, Worley PF", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "17088211", "url": "https://glygen.org/publication/PubMed/17088211" } ] }, { "title": "Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission.", "journal": "Neuron", "date": "2006", "authors": "Rial Verde EM, Lee-Osbourne J, Worley PF, Malinow R, Cline HT", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "17088212", "url": "https://glygen.org/publication/PubMed/17088212" } ] }, { "title": "CARPs are ubiquitin ligases that promote MDM2-independent p53 and phospho-p53ser20 degradation.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Yang W, Rozan LM, McDonald ER 3rd, Navaraj A, Liu JJ, Matthew EM, Wang W, Dicker DT, El-Deiry WS", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "17121812", "url": "https://glygen.org/publication/PubMed/17121812" } ] }, { "title": "Subcellular location of serum- and glucocorticoid-induced kinase-1 in renal and mammary epithelial cells.", "journal": "Am. J. Physiol.", "date": "2007", "authors": "Cordas Emily, N\u00e1ray-Fejes-T\u00f3th Anik\u00f3, Fejes-T\u00f3th G\u00e9za", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "17202226", "url": "https://glygen.org/publication/PubMed/17202226" } ] }, { "title": "Patterns of somatic mutation in human cancer genomes.", "journal": "Nature", "date": "2007", "authors": "Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "17344846", "url": "https://glygen.org/publication/PubMed/17344846" } ] }, { "title": "Epithelial sodium channel (ENaC) is multi-ubiquitinated at the cell surface.", "journal": "The Biochemical journal", "date": "2007", "authors": "Wiemuth D, Ke Y, Rohlfs M, McDonald FJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "17381423", "url": "https://glygen.org/publication/PubMed/17381423" } ] }, { "title": "Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4.", "journal": "Biochemical and biophysical research communications", "date": "2007", "authors": "Jeyaraj S, Boehmer C, Lang F, Palmada M", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "17382906", "url": "https://glygen.org/publication/PubMed/17382906" } ] }, { "title": "The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm.", "journal": "Cell", "date": "2007", "authors": "Lu B, Su Y, Das S, Liu J, Xia J, Ren D", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "17448995", "url": "https://glygen.org/publication/PubMed/17448995" } ] }, { "title": "The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression.", "journal": "Cell", "date": "2007", "authors": "Giorgi C, Yeo GW, Stone ME, Katz DB, Burge C, Turrigiano G, Moore MJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "17632064", "url": "https://glygen.org/publication/PubMed/17632064" } ] }, { "title": "Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2008", "authors": "Franceschini S, Ilari A, Verzili D, Zamparelli C, Antaramian A, Rueda A, Valdivia HH, Chiancone E, Colotti G", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "17699613", "url": "https://glygen.org/publication/PubMed/17699613" } ] }, { "title": "Characterization of human cardiac calsequestrin and its deleterious mutants.", "journal": "Journal of molecular biology", "date": "2007", "authors": "Kim E, Youn B, Kemper L, Campbell C, Milting H, Varsanyi M, Kang C", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "17881003", "url": "https://glygen.org/publication/PubMed/17881003" } ] }, { "title": "Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2007", "authors": "Messaoudi E, Kanhema T, Soule J, Tiron A, Dagyte G, da Silva B, Bramham CR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "17898216", "url": "https://glygen.org/publication/PubMed/17898216" } ] }, { "title": "Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP.", "journal": "Protein science : a publication of the Protein Society", "date": "2007", "authors": "Zhao B, Lehr R, Smallwood AM, Ho TF, Maley K, Randall T, Head MS, Koretke KK, Schnackenberg CG", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "17965184", "url": "https://glygen.org/publication/PubMed/17965184" } ] }, { "title": "A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Xiang M, Feng M, Muend S, Rao R", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18000046", "url": "https://glygen.org/publication/PubMed/18000046" } ] }, { "title": "Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3.", "journal": "FEBS letters", "date": "2007-12-11", "authors": "B\u00f6hmer C, Palmada M, Kenngott C, Lindner R, Klaus F, Laufer J, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "18005662", "url": "https://glygen.org/publication/PubMed/18005662" } ] }, { "title": "Rad GTPase deficiency leads to cardiac hypertrophy.", "journal": "Circulation", "date": "2007", "authors": "Chang L, Zhang J, Tseng YH, Xie CQ, Ilany J, Bruning JC, Sun Z, Zhu X, Cui T, Youker KA, Yang Q, Day SM, Kahn CR, Chen YE", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "18056528", "url": "https://glygen.org/publication/PubMed/18056528" } ] }, { "title": "Determinants of anion-proton coupling in mammalian endosomal CLC proteins.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Zdebik AA, Zifarelli G, Bergsdorf EY, Soliani P, Scheel O, Jentsch TJ, Pusch M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18063579", "url": "https://glygen.org/publication/PubMed/18063579" } ] }, { "title": "Serum- and glucocorticoid-inducible kinase 1 enhances zif268 expression through the mediation of SRF and CREB1 associated with spatial memory formation.", "journal": "Journal of neurochemistry", "date": "2008", "authors": "Tyan SW, Tsai MC, Lin CL, Ma YL, Lee EH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "18088355", "url": "https://glygen.org/publication/PubMed/18088355" } ] }, { "title": "Lyl1 interacts with CREB1 and alters expression of CREB1 target genes.", "journal": "Biochimica et biophysica acta", "date": "2008", "authors": "San-Marina S, Han Y, Suarez Saiz F, Trus MR, Minden MD", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "18160048", "url": "https://glygen.org/publication/PubMed/18160048" } ] }, { "title": "Regulation Fe65 localization to the nucleus by SGK1 phosphorylation of its Ser566 residue.", "journal": "BMB reports", "date": "2008", "authors": "Lee EJ, Chun J, Hyun S, Ahn HR, Jeong JM, Hong SK, Hong JT, Chang IK, Jeon HY, Han YS, Auh CK, Park JI, Kang SS", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "18304449", "url": "https://glygen.org/publication/PubMed/18304449" } ] }, { "title": "Molecular analysis of digenic inheritance in Bartter syndrome with sensorineural deafness.", "journal": "Journal of medical genetics", "date": "2008", "authors": "Nozu K, Inagaki T, Fu XJ, Nozu Y, Kaito H, Kanda K, Sekine T, Igarashi T, Nakanishi K, Yoshikawa N, Iijima K, Matsuo M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18310267", "url": "https://glygen.org/publication/PubMed/18310267" } ] }, { "title": "A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2008", "authors": "Arteaga Maria F, Coric Tatjana, Straub Christoph, Canessa Cecilia M", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "18334630", "url": "https://glygen.org/publication/PubMed/18334630" } ] }, { "title": "Transactivation of Krox-20 and Krox-24 promoters by the HTLV-1 Tax protein through common regulatory elements.", "journal": "Oncogene", "date": "1991", "authors": "Alexandre C, Charnay P, Verrier B", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "1833716", "url": "https://glygen.org/publication/PubMed/1833716" } ] }, { "title": "Bestrophin Cl- channels are highly permeable to HCO3-.", "journal": "American journal of physiology. Cell physiology", "date": "2008", "authors": "Qu Z, Hartzell HC", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18400985", "url": "https://glygen.org/publication/PubMed/18400985" } ] }, { "title": "The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.", "journal": "Nature", "date": "2008", "authors": "Graves AR, Curran PK, Smith CL, Mindell JA", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18449189", "url": "https://glygen.org/publication/PubMed/18449189" } ] }, { "title": "Active gene repression by the Egr2.NAB complex during peripheral nerve myelination.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Mager GM, Ward RM, Srinivasan R, Jang SW, Wrabetz L, Svaren J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "18456662", "url": "https://glygen.org/publication/PubMed/18456662" } ] }, { "title": "Characterization of the sodium/hydrogen exchanger NHA2.", "journal": "Journal of the American Society of Nephrology : JASN", "date": "2008", "authors": "Fuster DG, Zhang J, Shi M, Bobulescu IA, Andersson S, Moe OW", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18508966", "url": "https://glygen.org/publication/PubMed/18508966" } ] }, { "title": "Disruption of Krox20-Nab interaction in the mouse leads to peripheral neuropathy with biphasic evolution.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2008", "authors": "Desmazieres A, Decker L, Vallat JM, Charnay P, Gilardi-Hebenstreit P", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "18524893", "url": "https://glygen.org/publication/PubMed/18524893" } ] }, { "title": "mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation.", "journal": "Molecular cell", "date": "2008", "authors": "Hong F, Larrea MD, Doughty C, Kwiatkowski DJ, Squillace R, Slingerland JM", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "18570873", "url": "https://glygen.org/publication/PubMed/18570873" } ] }, { "title": "Nucleotide sequence and regulatory studies of VGF, a nervous system-specific mRNA that is rapidly and relatively selectively induced by nerve growth factor.", "journal": "Journal of neurochemistry", "date": "1991", "authors": "Salton SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "1861162", "url": "https://glygen.org/publication/PubMed/1861162" } ] }, { "title": "Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assay.", "journal": "The European journal of neuroscience", "date": "2008", "authors": "Donier E, Rugiero F, Jacob C, Wood JN", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18662336", "url": "https://glygen.org/publication/PubMed/18662336" } ] }, { "title": "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.", "journal": "Molecular cell", "date": "2008", "authors": "Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141-1" } ], "reference": [ { "type": "PubMed", "id": "18691976", "url": "https://glygen.org/publication/PubMed/18691976" } ] }, { "title": "TMEM16A confers receptor-activated calcium-dependent chloride conductance.", "journal": "Nature", "date": "2008", "authors": "Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "18724360", "url": "https://glygen.org/publication/PubMed/18724360" } ] }, { "title": "An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.", "journal": "American journal of physiology. Renal physiology", "date": "2008-11", "authors": "Raikwar Nandita S, Snyder Peter M, Thomas Christie P", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "18753299", "url": "https://glygen.org/publication/PubMed/18753299" } ] }, { "title": "mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).", "journal": "The Biochemical journal", "date": "2008", "authors": "Garcia-Martinez JM, Alessi DR", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "18925875", "url": "https://glygen.org/publication/PubMed/18925875" } ] }, { "title": "mTORC2 is the hydrophobic motif kinase for SGK1.", "journal": "The Biochemical journal", "date": "2008", "authors": "Yan L, Mieulet V, Lamb RF", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "19025518", "url": "https://glygen.org/publication/PubMed/19025518" } ] }, { "title": "CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.", "journal": "Molecular cell", "date": "2008", "authors": "Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "19061646", "url": "https://glygen.org/publication/PubMed/19061646" } ] }, { "title": "Regulation of a third conserved phosphorylation site in SGK1.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Chen W, Chen Y, Xu BE, Juang YC, Stippec S, Zhao Y, Cobb MH", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "19068477", "url": "https://glygen.org/publication/PubMed/19068477" } ] }, { "title": "Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Kawashima T, Okuno H, Nonaka M, Adachi-Morishima A, Kyo N, Okamura M, Takemoto-Kimura S, Worley PF, Bito H", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "19116276", "url": "https://glygen.org/publication/PubMed/19116276" } ] }, { "title": "Voltage-dependent and -independent titration of specific residues accounts for complex gating of a ClC chloride channel by extracellular protons.", "journal": "The Journal of physiology", "date": "2009", "authors": "Niemeyer MI, Cid LP, Yusef YR, Briones R, Sepulveda FV", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19153159", "url": "https://glygen.org/publication/PubMed/19153159" } ] }, { "title": "The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2009", "authors": "Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "19193899", "url": "https://glygen.org/publication/PubMed/19193899" } ] }, { "title": "Neuroendocrine regulatory peptide-1 and -2: novel bioactive peptides processed from VGF.", "journal": "Cellular and molecular life sciences : CMLS", "date": "2009", "authors": "Toshinai K, Nakazato M", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "19194657", "url": "https://glygen.org/publication/PubMed/19194657" } ] }, { "title": "Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents.", "journal": "The Journal of physiology", "date": "2009", "authors": "Hamann M, Gibson A, Davies N, Jowett A, Walhin JP, Partington L, Affleck K, Trezise D, Main M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19307298", "url": "https://glygen.org/publication/PubMed/19307298" } ] }, { "title": "Large-scale proteomics analysis of the human kinome.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Keri G, Mann M, Daub H", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "19369195", "url": "https://glygen.org/publication/PubMed/19369195" } ] }, { "title": "Epithelial sodium channel regulated by differential composition of a signaling complex.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Soundararajan R, Melters D, Shih IC, Wang J, Pearce D", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19380724", "url": "https://glygen.org/publication/PubMed/19380724" } ] }, { "title": "NAADP mobilizes calcium from acidic organelles through two-pore channels.", "journal": "Nature", "date": "2009", "authors": "Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19387438", "url": "https://glygen.org/publication/PubMed/19387438" } ] }, { "title": "Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.", "journal": "Journal of hepatology", "date": "2009", "authors": "Won M, Park KA, Byun HS, Kim YR, Choi BL, Hong JH, Park J, Seok JH, Lee YH, Cho CH, Song IS, Kim YK, Shen HM, Hur GM", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "19447520", "url": "https://glygen.org/publication/PubMed/19447520" } ] }, { "title": "The physiological impact of the serum and glucocorticoid-inducible kinase SGK1.", "journal": "Current opinion in nephrology and hypertension", "date": "2009", "authors": "Lang F, Artunc F, Vallon V", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "19584721", "url": "https://glygen.org/publication/PubMed/19584721" } ] }, { "title": "Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling.", "journal": "The Journal of cell biology", "date": "2009", "authors": "Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19620632", "url": "https://glygen.org/publication/PubMed/19620632" } ] }, { "title": "Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.", "journal": "Journal of molecular medicine (Berlin, Germany)", "date": "2009", "authors": "Amato R, D'Antona L, Porciatti G, Agosti V, Menniti M, Rinaldo C, Costa N, Bellacchio E, Mattarocci S, Fuiano G, Soddu S, Paggi MG, Lang F, Perrotti N", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "19756449", "url": "https://glygen.org/publication/PubMed/19756449" } ] }, { "title": "A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "19805105", "url": "https://glygen.org/publication/PubMed/19805105" } ] }, { "title": "Crofelemer, an antisecretory antidiarrheal proanthocyanidin oligomer extracted from Croton lechleri, targets two distinct intestinal chloride channels.", "journal": "Molecular pharmacology", "date": "2010", "authors": "Tradtrantip L, Namkung W, Verkman AS", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19808995", "url": "https://glygen.org/publication/PubMed/19808995" } ] }, { "title": "ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.", "journal": "The EMBO journal", "date": "2009", "authors": "Cheng Q, Chen L, Li Z, Lane WS, Chen J", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "19816404", "url": "https://glygen.org/publication/PubMed/19816404" } ] }, { "title": "MdmX is a substrate for the deubiquitinating enzyme USP2a.", "journal": "Oncogene", "date": "2010", "authors": "Allende-Vega N, Sparks A, Lane DP, Saville MK", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "19838211", "url": "https://glygen.org/publication/PubMed/19838211" } ] }, { "title": "Rad as a novel regulator of excitation-contraction coupling and beta-adrenergic signaling in heart.", "journal": "Circulation research", "date": "2010", "authors": "Wang G, Zhu X, Xie W, Han P, Li K, Sun Z, Wang Y, Chen C, Song R, Cao C, Zhang J, Wu C, Liu J, Cheng H", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "19926875", "url": "https://glygen.org/publication/PubMed/19926875" } ] }, { "title": "Molecular and clinical heterogeneity in CLCN7-dependent osteopetrosis: report of 20 novel mutations.", "journal": "Human mutation", "date": "2010", "authors": "Pangrazio A, Pusch M, Caldana E, Frattini A, Lanino E, Tamhankar PM, Phadke S, Lopez AG, Orchard P, Mihci E, Abinun M, Wright M, Vettenranta K, Bariae I, Melis D, Tezcan I, Baumann C, Locatelli F, Zecca M, Horwitz E, Mansour LS, Van Roij M, Vezzoni P, Villa A, Sobacchi C", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "19953639", "url": "https://glygen.org/publication/PubMed/19953639" } ] }, { "title": "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.", "journal": "Science signaling", "date": "2010", "authors": "Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "iPTMnet", "id": "O00141-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141-1" } ], "reference": [ { "type": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ] }, { "title": "Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells.", "journal": "Molecular and cellular biology", "date": "1991", "authors": "Salton SR, Fischberg DJ, Dong KW", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2017159", "url": "https://glygen.org/publication/PubMed/2017159" } ] }, { "title": "mTOR complex-2 activates ENaC by phosphorylating SGK1.", "journal": "Journal of the American Society of Nephrology : JASN", "date": "2010", "authors": "Lu M, Wang J, Jones KT, Ives HE, Feldman ME, Yao LJ, Shokat KM, Ashrafi K, Pearce D", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" }, { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "20338997", "url": "https://glygen.org/publication/PubMed/20338997" } ] }, { "title": "Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure.", "journal": "Cardiovascular research", "date": "2010", "authors": "Ono M, Yano M, Hino A, Suetomi T, Xu X, Susa T, Uchinoumi H, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Koseki N, Kyushiki H, Ikemoto N, Matsuzaki M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "20388639", "url": "https://glygen.org/publication/PubMed/20388639" } ] }, { "title": "v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements.", "journal": "The Journal of biological chemistry", "date": "1991", "authors": "Qureshi SA, Cao XM, Sukhatme VP, Foster DA", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2040600", "url": "https://glygen.org/publication/PubMed/2040600" } ] }, { "title": "Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway.", "journal": "Biochemical and biophysical research communications", "date": "2010", "authors": "Lyo D, Xu L, Foster DA", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "20438709", "url": "https://glygen.org/publication/PubMed/20438709" } ] }, { "title": "The late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Neagoe I, Stauber T, Fidzinski P, Bergsdorf EY, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "20466723", "url": "https://glygen.org/publication/PubMed/20466723" } ] }, { "title": "EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin.", "journal": "Journal of cellular biochemistry", "date": "2010", "authors": "Kumbrink J, Kirsch KH, Johnson JP", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "20506119", "url": "https://glygen.org/publication/PubMed/20506119" } ] }, { "title": "The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19.", "journal": "Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology", "date": "2010", "authors": "B\u00f6hmer Christoph, Sopjani Mentor, Klaus Fabian, Lindner Ricco, Laufer J\u00f6rg, Jeyaraj Shankarganesh, Lang Florian, Palmada Monica", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "20511718", "url": "https://glygen.org/publication/PubMed/20511718" } ] }, { "title": "5' upstream sequence and genomic structure of the human primary response gene, EGR-1/TIS8.", "journal": "Oncogene", "date": "1991", "authors": "Sakamoto KM, Bardeleben C, Yates KE, Raines MA, Golde DW, Gasson JC", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2052361", "url": "https://glygen.org/publication/PubMed/2052361" } ] }, { "title": "Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Heise CJ, Xu BE, Deaton SL, Cha SK, Cheng CJ, Earnest S, Sengupta S, Juang YC, Stippec S, Xu Y, Zhao Y, Huang CL, Cobb MH", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "20525693", "url": "https://glygen.org/publication/PubMed/20525693" } ] }, { "title": "Significance of SGK1 in the regulation of neuronal function.", "journal": "J. Physiol. (Lond.)", "date": "2010", "authors": "Lang Florian, Strutz-Seebohm Nathalie, Seebohm Guiscard, Lang Undine E", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "20530112", "url": "https://glygen.org/publication/PubMed/20530112" } ] }, { "title": "Barttin activates ClC-K channel function by modulating gating.", "journal": "Journal of the American Society of Nephrology : JASN", "date": "2010", "authors": "Fischer M, Janssen AG, Fahlke C", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "20538786", "url": "https://glygen.org/publication/PubMed/20538786" } ] }, { "title": "Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.", "journal": "Journal of molecular biology", "date": "2010", "authors": "Sarkari F, La Delfa A, Arrowsmith CH, Frappier L, Sheng Y, Saridakis V", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "20713061", "url": "https://glygen.org/publication/PubMed/20713061" } ] }, { "title": "The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family.", "journal": "Molecular and cellular biology", "date": "1991", "authors": "Crosby SD, Puetz JJ, Simburger KS, Fahrner TJ, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2072895", "url": "https://glygen.org/publication/PubMed/2072895" } ] }, { "title": "Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.", "journal": "PloS one", "date": "2010", "authors": "Wiemuth D, Lott JS, Ly K, Ke Y, Teesdale-Spittle P, Snyder PM, McDonald FJ", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "20730100", "url": "https://glygen.org/publication/PubMed/20730100" } ] }, { "title": "Second AKT: the rise of SGK in cancer signalling.", "journal": "Growth Factors", "date": "2010", "authors": "Bruhn MA, Pearson RB, Hannan RD, Sheppard KE", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "20919962", "url": "https://glygen.org/publication/PubMed/20919962" } ] }, { "title": "Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.", "journal": "Neuron", "date": "2010", "authors": "Lu B, Zhang Q, Wang H, Wang Y, Nakayama M, Ren D", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "21040849", "url": "https://glygen.org/publication/PubMed/21040849" } ] }, { "title": "Synaptic activity-responsive element (SARE): A unique genomic structure with an unusual sensitivity to neuronal activity.", "journal": "Communicative & integrative biology", "date": "2010", "authors": "Inoue M, Yagishita-Kyo N, Nonaka M, Kawashima T, Okuno H, Bito H", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "21057636", "url": "https://glygen.org/publication/PubMed/21057636" } ] }, { "title": "Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.", "journal": "Molecular and cellular biology", "date": "1990", "authors": "Cao XM, Koski RA, Gashler A, McKiernan M, Morris CF, Gaffney R, Hay RV, Sukhatme VP", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2109185", "url": "https://glygen.org/publication/PubMed/2109185" } ] }, { "title": "Activation and function of immediate-early genes in the nervous system.", "journal": "Biochemistry and cell biology = Biochimie et biologie cellulaire", "date": "2011", "authors": "Perez-Cadahia B, Drobic B, Davie JR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "21326363", "url": "https://glygen.org/publication/PubMed/21326363" } ] }, { "title": "ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis.", "journal": "Journal of cell science", "date": "2011", "authors": "Hong SH, Lee JH, Lee JB, Ji J, Bhatia M", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "21486943", "url": "https://glygen.org/publication/PubMed/21486943" } ] }, { "title": "ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity.", "journal": "The EMBO journal", "date": "2011", "authors": "Leisle L, Ludwig CF, Wagner FA, Jentsch TJ, Stauber T", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "21527911", "url": "https://glygen.org/publication/PubMed/21527911" } ] }, { "title": "VGF: an inducible gene product, precursor of a diverse array of neuro-endocrine peptides and tissue-specific disease biomarkers.", "journal": "Journal of chemical neuroanatomy", "date": "2011", "authors": "Ferri GL, Noli B, Brancia C, D'Amato F, Cocco C", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "21621608", "url": "https://glygen.org/publication/PubMed/21621608" } ] }, { "title": "Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Pant V, Xiong S, Iwakuma T, Quintas-Cardama A, Lozano G", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "21730132", "url": "https://glygen.org/publication/PubMed/21730132" } ] }, { "title": "The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Huang L, Yan Z, Liao X, Li Y, Yang J, Wang ZG, Zuo Y, Kawai H, Shadfan M, Ganapathy S, Yuan ZM", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "21730163", "url": "https://glygen.org/publication/PubMed/21730163" } ] }, { "title": "Dynamics of the phosphoinositide 3-kinase p110delta interaction with p85alpha and membranes reveals aspects of regulation distinct from p110alpha.", "journal": "Structure (London, England : 1993)", "date": "2011", "authors": "Burke JE, Vadas O, Berndt A, Finegan T, Perisic O, Williams RL", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "21827948", "url": "https://glygen.org/publication/PubMed/21827948" } ] }, { "title": "Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.", "journal": "Molecular biology of the cell", "date": "2011", "authors": "He P, Lee SJ, Lin S, Seidler U, Lang F, Fejes-Toth G, Naray-Fejes-Toth A, Yun CC", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "21865597", "url": "https://glygen.org/publication/PubMed/21865597" } ] }, { "title": "Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1.", "journal": "Cellular signalling", "date": "2012", "authors": "Baskin R, Sayeski PP", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "21963429", "url": "https://glygen.org/publication/PubMed/21963429" } ] }, { "title": "The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.", "journal": "Experimental physiology", "date": "2012", "authors": "Scudieri P, Sondo E, Ferrera L, Galietta LJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "21984732", "url": "https://glygen.org/publication/PubMed/21984732" } ] }, { "title": "Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage.", "journal": "Molecular and cellular biology", "date": "2011", "authors": "Cheng Q, Cross B, Li B, Chen L, Li Z, Chen J", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "21986495", "url": "https://glygen.org/publication/PubMed/21986495" } ] }, { "title": "Early growth response 1--a transcription factor in the crossfire of signal transduction cascades.", "journal": "Indian journal of biochemistry & biophysics", "date": "2011", "authors": "Pagel JI, Deindl E", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "22053691", "url": "https://glygen.org/publication/PubMed/22053691" } ] }, { "title": "Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell differentiation.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Mullenbrock S, Shah J, Cooper GM", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "22065583", "url": "https://glygen.org/publication/PubMed/22065583" } ] }, { "title": "The nucleosome remodeling and deacetylase chromatin remodeling (NuRD) complex is required for peripheral nerve myelination.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2012", "authors": "Hung H, Kohnken R, Svaren J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "22302795", "url": "https://glygen.org/publication/PubMed/22302795" } ] }, { "title": "Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody.", "journal": "Thrombosis research", "date": "1990", "authors": "Fleck RA, Rao LV, Rapaport SI, Varki N", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2237820", "url": "https://glygen.org/publication/PubMed/2237820" } ] }, { "title": "Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons.", "journal": "Open biology", "date": "2012", "authors": "Lapatsina L, Jira JA, Smith ES, Poole K, Kozlenkov A, Bilbao D, Lewin GR, Heppenstall PA", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "22773952", "url": "https://glygen.org/publication/PubMed/22773952" } ] }, { "title": "Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.", "journal": "Breast cancer research and treatment", "date": "2012", "authors": "Hall BA, Kim TY, Skor MN, Conzen SD", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "22842983", "url": "https://glygen.org/publication/PubMed/22842983" } ] }, { "title": "Anoctamins are a family of Ca2+-activated Cl- channels.", "journal": "Journal of cell science", "date": "2012", "authors": "Tian Y, Schreiber R, Kunzelmann K", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "22946059", "url": "https://glygen.org/publication/PubMed/22946059" } ] }, { "title": "Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum.", "journal": "The Journal of biological chemistry", "date": "1990", "authors": "Zorzato F, Fujii J, Otsu K, Phillips M, Green NM, Lai FA, Meissner G, MacLennan DH", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "2298749", "url": "https://glygen.org/publication/PubMed/2298749" } ] }, { "title": "Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.", "journal": "The Journal of biological chemistry", "date": "2012", "authors": "Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "23112050", "url": "https://glygen.org/publication/PubMed/23112050" } ] }, { "title": "Characterization and localization to human chromosome 1 of human fast-twitch skeletal muscle calsequestrin gene.", "journal": "Somatic cell and molecular genetics", "date": "1990", "authors": "Fujii J, Willard HF, MacLennan DH", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "2321095", "url": "https://glygen.org/publication/PubMed/2321095" } ] }, { "title": "Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors.", "journal": "The Biochemical journal", "date": "2013", "authors": "Sommer EM, Dry H, Cross D, Guichard S, Davies BR, Alessi DR", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "23581296", "url": "https://glygen.org/publication/PubMed/23581296" } ] }, { "title": "Crofelemer, a novel antisecretory agent approved for the treatment of HIV-associated diarrhea.", "journal": "Drugs of today (Barcelona, Spain : 1998)", "date": "2013", "authors": "Yeo QM, Crutchley R, Cottreau J, Tucker A, Garey KW", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "23616951", "url": "https://glygen.org/publication/PubMed/23616951" } ] }, { "title": "Identification of a functional TPH1 polymorphism associated with irritable bowel syndrome bowel habit subtypes.", "journal": "The American journal of gastroenterology", "date": "2013", "authors": "Grasberger H, Chang L, Shih W, Presson AP, Sayuk GS, Newberry RD, Karagiannides I, Pothoulakis C, Mayer E, Merchant JL", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "24060757", "url": "https://glygen.org/publication/PubMed/24060757" } ] }, { "title": "Id proteins: small molecules, mighty regulators.", "journal": "Current topics in developmental biology", "date": "2014", "authors": "Ling F, Kang B, Sun XH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "25248477", "url": "https://glygen.org/publication/PubMed/25248477" } ] }, { "title": "Calmodulin modulation of single sarcoplasmic reticulum Ca2+-release channels from cardiac and skeletal muscle.", "journal": "Circulation research", "date": "1989", "authors": "Smith JS, Rousseau E, Meissner G", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "2536303", "url": "https://glygen.org/publication/PubMed/2536303" } ] }, { "title": "Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of DeltaF508-cystic fibrosis transmembrane conductance regulator (DeltaF508-CFTR).", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Caohuy H, Yang Q, Eudy Y, Ha TA, Xu AE, Glover M, Frizzell RA, Jozwik C, Pollard HB", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "25384981", "url": "https://glygen.org/publication/PubMed/25384981" } ] }, { "title": "Transcriptional regulation of the neuropeptide VGF by the neuron-restrictive silencer factor/neuron-restrictive silencer element.", "journal": "Neuroreport", "date": "2015", "authors": "Moon SM, Kim JS, Park BR, Kim DK, Kim SG, Kim HJ, Chun HS, Lee BK, Kim CS", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "25569790", "url": "https://glygen.org/publication/PubMed/25569790" } ] }, { "title": "Arc is a flexible modular protein capable of reversible self-oligomerization.", "journal": "The Biochemical journal", "date": "2015", "authors": "Myrum C, Baumann A, Bustad HJ, Flydal MI, Mariaule V, Alvira S, Cuellar J, Haavik J, Soule J, Valpuesta JM, Marquez JA, Martinez A, Bramham CR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "25748042", "url": "https://glygen.org/publication/PubMed/25748042" } ] }, { "title": "How it all starts: Initiation of the clotting cascade.", "journal": "Critical reviews in biochemistry and molecular biology", "date": "2015", "authors": "Smith SA, Travers RJ, Morrissey JH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "26018600", "url": "https://glygen.org/publication/PubMed/26018600" } ] }, { "title": "A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2.", "journal": "American journal of physiology. Gastrointestinal and liver physiology", "date": "2015", "authors": "Strege PR, Bernard CE, Mazzone A, Linden DR, Beyder A, Gibbons SJ, Farrugia G", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "26359375", "url": "https://glygen.org/publication/PubMed/26359375" } ] }, { "title": "Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker.", "journal": "British journal of pharmacology", "date": "2016", "authors": "Ta CM, Adomaviciene A, Rorsman NJ, Garnett H, Tammaro P", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "26562072", "url": "https://glygen.org/publication/PubMed/26562072" } ] }, { "title": "A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway.", "journal": "The EMBO journal", "date": "1989", "authors": "Possenti R, Eldridge JD, Paterson BM, Grasso A, Levi A", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "2676516", "url": "https://glygen.org/publication/PubMed/2676516" } ] }, { "title": "Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs.", "journal": "Scientific reports", "date": "2016", "authors": "Lyu JW, Yuan B, Cheng TL, Qiu ZL, Zhou WH", "evidence": [ { "database": "Reactome", "id": "R-HSA-8986944", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8986944" } ], "reference": [ { "type": "PubMed", "id": "26843422", "url": "https://glygen.org/publication/PubMed/26843422" } ] }, { "title": "Structural Basis for Substrate Selectivity of the E3 Ligase COP1.", "journal": "Structure (London, England : 1993)", "date": "2016", "authors": "Uljon S, Xu X, Durzynska I, Stein S, Adelmant G, Marto JA, Pear WS, Blacklow SC", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "27041596", "url": "https://glygen.org/publication/PubMed/27041596" } ] }, { "title": "Combined Id1 and Id3 Deletion Leads to Severe Erythropoietic Disturbances.", "journal": "PloS one", "date": "2016", "authors": "Zhao Q, Chang C, Gonzalez JP, Alzahrani K, Button JL, Fraidenraich D", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "27128622", "url": "https://glygen.org/publication/PubMed/27128622" } ] }, { "title": "Gene regulation in the immediate-early response process.", "journal": "Advances in biological regulation", "date": "2016", "authors": "Bahrami S, Drablos F", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "27220739", "url": "https://glygen.org/publication/PubMed/27220739" } ] }, { "title": "Integrating mass spectrometry with MD simulations reveals the role of lipids in Na(+)/H(+) antiporters.", "journal": "Nature communications", "date": "2017", "authors": "Landreh M, Marklund EG, Uzdavinys P, Degiacomi MT, Coincon M, Gault J, Gupta K, Liko I, Benesch JL, Drew D, Robinson CV", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "28071645", "url": "https://glygen.org/publication/PubMed/28071645" } ] }, { "title": "Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells.", "journal": "PloS one", "date": "2017", "authors": "Adams KW, Kletsov S, Lamm RJ, Elman JS, Mullenbrock S, Cooper GM", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "28076410", "url": "https://glygen.org/publication/PubMed/28076410" } ] }, { "title": "Heterogeneous nuclear ribonucleoprotein M associates with mTORC2 and regulates muscle differentiation.", "journal": "Scientific reports", "date": "2017", "authors": "Chen WY, Lin CL, Chuang JH, Chiu FY, Sun YY, Liang MC, Lin Y", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "28106162", "url": "https://glygen.org/publication/PubMed/28106162" } ] }, { "title": "Dissecting the proton transport pathway in electrogenic Na(+)/H(+) antiporters.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2017", "authors": "Uzdavinys P, Coincon M, Nji E, Ndi M, Winkelmann I, von Ballmoos C, Drew D", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "28154142", "url": "https://glygen.org/publication/PubMed/28154142" } ] }, { "title": "Binding and inhibition of the ternary complex factor Elk-4/Sap1 by the adapter protein Dok-4.", "journal": "The Biochemical journal", "date": "2017", "authors": "Hooker E, Baldwin C, Roodman V, Batra A, Isa NN, Takano T, Lemay S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "28275114", "url": "https://glygen.org/publication/PubMed/28275114" } ] }, { "title": "ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription.", "journal": "Molecular cell", "date": "2017", "authors": "Esnault C, Gualdrini F, Horswell S, Kelly G, Stewart A, East P, Matthews N, Treisman R", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "28286024", "url": "https://glygen.org/publication/PubMed/28286024" } ] }, { "title": "Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models.", "journal": "Oncotarget", "date": "2017", "authors": "Schmidt KM, Hellerbrand C, Ruemmele P, Michalski CW, Kong B, Kroemer A, Hackl C, Schlitt HJ, Geissler EK, Lang SA", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "28445935", "url": "https://glygen.org/publication/PubMed/28445935" } ] }, { "title": "Inhibition of the Schizophrenia-Associated MicroRNA miR-137 Disrupts Nrg1alpha Neurodevelopmental Signal Transduction.", "journal": "Cell reports", "date": "2017", "authors": "Thomas KT, Anderson BR, Shah N, Zimmer SE, Hawkins D, Valdez AN, Gu Q, Bassell GJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-8986944", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8986944" } ], "reference": [ { "type": "PubMed", "id": "28683304", "url": "https://glygen.org/publication/PubMed/28683304" } ] }, { "title": "Arginyl dipeptides increase the frequency of NaCl-elicited responses via epithelial sodium channel alpha and delta subunits in cultured human fungiform taste papillae cells.", "journal": "Scientific reports", "date": "2017", "authors": "Xu JJ, Elkaddi N, Garcia-Blanco A, Spielman AI, Bachmanov AA, Chung HY, Ozdener MH", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "28790369", "url": "https://glygen.org/publication/PubMed/28790369" } ] }, { "title": "Identification of 4-phenylquinolin-2(1H)-one as a specific allosteric inhibitor of Akt.", "journal": "Scientific reports", "date": "2017-09-15", "authors": "Huang Bill X, Newcomer Kenny, Kevala Karl, Barnaeva Elena, Zheng Wei, Hu Xin, Patnaik Samarjit, Southall Noel, Marugan Juan, Ferrer Marc, Kim Hee-Yong", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "28916818", "url": "https://glygen.org/publication/PubMed/28916818" } ] }, { "title": "Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells.", "journal": "Toxins", "date": "2018", "authors": "Yang G, Pillich H, White R, Czikora I, Pochic I, Yue Q, Hudel M, Gorshkov B, Verin A, Sridhar S, Isales CM, Eaton DC, Hamacher J, Chakraborty T, Lucas R", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "29439494", "url": "https://glygen.org/publication/PubMed/29439494" } ] }, { "title": "The Arc of cognition: Signaling cascades regulating Arc and implications for cognitive function and disease.", "journal": "Seminars in cell & developmental biology", "date": "2018", "authors": "Epstein I, Finkbeiner S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "29559111", "url": "https://glygen.org/publication/PubMed/29559111" } ] }, { "title": "WNK1 kinase and its partners Akt, SGK1 and NBC-family Na(+)/HCO3(-) cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling.", "journal": "Oncotarget", "date": "2018", "authors": "Chen W, Zebaze LN, Dong J, Chezeau L, Inquimbert P, Hugel S, Niu S, Bihel F, Boutant E, Real E, Villa P, Junier MP, Chneiweiss H, Hibert M, Haiech J, Kilhoffer MC, Zeniou M", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "29930759", "url": "https://glygen.org/publication/PubMed/29930759" } ] }, { "title": "STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1.", "journal": "Cell & bioscience", "date": "2019", "authors": "Picco ME, Castro MV, Quezada MJ, Barbero G, Villanueva MB, Fernandez NB, Kim H, Lopez-Bergami P", "evidence": [ { "database": "iPTMnet", "id": "O00141", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00141" } ], "reference": [ { "type": "PubMed", "id": "30622697", "url": "https://glygen.org/publication/PubMed/30622697" } ] }, { "title": "A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.", "journal": "Cell", "date": "1988", "authors": "Sukhatme VP, Cao XM, Chang LC, Tsai-Morris CH, Stamenkovich D, Ferreira PC, Cohen DR, Edwards SA, Shows TB, Curran T, et al.", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "3127059", "url": "https://glygen.org/publication/PubMed/3127059" } ] }, { "title": "WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport.", "journal": "Journal of cell science", "date": "2022-12-01", "authors": "Saha Bidisha, Leite-Dellova Deise C A, Demko John, S\u00f8rensen Mads Vaarby, Takagi Enzo, Gleason Catherine E, Shabbir Waheed, Pearce David", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "36373794", "url": "https://glygen.org/publication/PubMed/36373794" } ] }, { "title": "A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.", "journal": "Science (New York, N.Y.)", "date": "1987", "authors": "Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "3672127", "url": "https://glygen.org/publication/PubMed/3672127" } ] }, { "title": "Induction of SGK1 via glucocorticoid-influenced clinical outcome of triple-negative breast cancer patients.", "journal": "Breast cancer research and treatment", "date": "2023-06-07", "authors": "Zhang Junjia, Miki Yasuhiro, Iwabuchi Erina, Xu Junyao, Kanai Ayako, Sagara Yasuaki, Ohi Yasuyo, Rai Yoshiaki, Yamaguchi Rin, Tanaka Maki, Ishida Takanori, Suzuki Takashi, Sasano Hironobu", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" } ], "reference": [ { "type": "PubMed", "id": "37286891", "url": "https://glygen.org/publication/PubMed/37286891" } ] }, { "title": "[SGK1 as a therapeutic target for central nervous system diseases].", "journal": "Sheng li xue bao : [Acta physiologica Sinica]", "date": "2023-06-25", "authors": "Xing Ya-Kang, Luo Wei, Fan Meng-Yao, Tan Ya-Wei, Li Xiao", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" } ], "reference": [ { "type": "PubMed", "id": "37340653", "url": "https://glygen.org/publication/PubMed/37340653" } ] }, { "title": "Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation.", "journal": "The Journal of biological chemistry", "date": "2023-08", "authors": "Gu Wenxue, Zheng Hongyan, Canessa Cecilia M", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" } ], "reference": [ { "type": "PubMed", "id": "37343701", "url": "https://glygen.org/publication/PubMed/37343701" } ] }, { "title": "Role of Serum/Glucocorticoid-Regulated Kinase 1 (SGK1) in Immune and Inflammatory Diseases.", "journal": "Inflammation", "date": "2023-06-24", "authors": "Bian Xixi, Xue Honglu, Jing Dehuai, Wang Yan, Zhou Guangxi, Zhu Fengqin", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" } ], "reference": [ { "type": "PubMed", "id": "37353719", "url": "https://glygen.org/publication/PubMed/37353719" } ] }, { "title": "Proteomics on malignant pleural effusions reveals ER\u03b1 loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.", "journal": "Molecular oncology", "date": "2024-01", "authors": "Mayayo-Peralta Isabel, Debets Donna O, Prekovic Stefan, Schuurman Karianne, Beerthuijzen Suzanne, Almekinders Mathilde, Sanders Joyce, Moelans Cathy B, Saleiro Sandra, Wesseling Jelle, van Diest Paul J, Henrique Rui, Jer\u00f3nimo Carmen, Altelaar Maarten, Zwart Wilbert", "evidence": [ { "database": "RefSeq", "id": "NP_001137148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137148" } ], "reference": [ { "type": "PubMed", "id": "37854018", "url": "https://glygen.org/publication/PubMed/37854018" } ] }, { "title": "Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals.", "journal": "Molecular and cellular neurosciences", "date": "1995", "authors": "Bonni A, Ginty DD, Dudek H, Greenberg ME", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7551568", "url": "https://glygen.org/publication/PubMed/7551568" } ] }, { "title": "Molecular cloning of the cDNA encoding human skeletal muscle triadin and its localisation to chromosome 6q22-6q23.", "journal": "European journal of biochemistry", "date": "1995", "authors": "Taske NL, Eyre HJ, O'Brien RO, Sutherland GR, Denborough MA, Foster PS", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "7588753", "url": "https://glygen.org/publication/PubMed/7588753" } ] }, { "title": "An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Tang D, Yeung J, Lee KY, Matsushita M, Matsui H, Tomizawa K, Hatase O, Wang JH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7592934", "url": "https://glygen.org/publication/PubMed/7592934" } ] }, { "title": "Tissue-specific processing of the neuroendocrine protein VGF.", "journal": "Journal of neurochemistry", "date": "1995", "authors": "Trani E, Ciotti T, Rinaldi AM, Canu N, Ferri GL, Levi A, Possenti R", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7595538", "url": "https://glygen.org/publication/PubMed/7595538" } ] }, { "title": "Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Lee HJ, Mignacca RC, Sakamoto KM", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7608156", "url": "https://glygen.org/publication/PubMed/7608156" } ] }, { "title": "Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1995", "authors": "Russo MW, Sevetson BR, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7624335", "url": "https://glygen.org/publication/PubMed/7624335" } ] }, { "title": "Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.", "journal": "Nature", "date": "1995", "authors": "Burgering BM, Coffer PJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "7637810", "url": "https://glygen.org/publication/PubMed/7637810" } ] }, { "title": "Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein.", "journal": "Genomics", "date": "1995", "authors": "Borsani G, Rugarli EI, Taglialatela M, Wong C, Ballabio A", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "7665160", "url": "https://glygen.org/publication/PubMed/7665160" } ] }, { "title": "Mapping of the p53 and mdm-2 interaction domains.", "journal": "Molecular and cellular biology", "date": "1993", "authors": "Chen J, Marechal V, Levine AJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "7686617", "url": "https://glygen.org/publication/PubMed/7686617" } ] }, { "title": "Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Kovacsovics TJ, Bachelot C, Toker A, Vlahos CJ, Duckworth B, Cantley LC, Hartwig JH", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "7744773", "url": "https://glygen.org/publication/PubMed/7744773" } ] }, { "title": "Somatodendritic expression of an immediate early gene is regulated by synaptic activity.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1995", "authors": "Link W, Konietzko U, Kauselmann G, Krug M, Schwanke B, Frey U, Kuhl D", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7777577", "url": "https://glygen.org/publication/PubMed/7777577" } ] }, { "title": "Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites.", "journal": "Oncogene", "date": "1995", "authors": "Zauberman A, Lupo A, Oren M", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "7784084", "url": "https://glygen.org/publication/PubMed/7784084" } ] }, { "title": "Cloning of a putative human voltage-gated chloride channel (CIC-2) cDNA widely expressed in human tissues.", "journal": "Human molecular genetics", "date": "1995", "authors": "Cid LP, Montrose-Rafizadeh C, Smith DI, Guggino WB, Cutting GR", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "7795595", "url": "https://glygen.org/publication/PubMed/7795595" } ] }, { "title": "A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor cross-linking in B lymphocytes.", "journal": "Molecular and cellular biology", "date": "1995", "authors": "McMahon SB, Monroe JG", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7823924", "url": "https://glygen.org/publication/PubMed/7823924" } ] }, { "title": "Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites.", "journal": "Neuron", "date": "1995", "authors": "Lyford GL, Yamagata K, Kaufmann WE, Barnes CA, Sanders LK, Copeland NG, Gilbert DJ, Jenkins NA, Lanahan AA, Worley PF", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7857651", "url": "https://glygen.org/publication/PubMed/7857651" } ] }, { "title": "The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes.", "journal": "Science (New York, N.Y.)", "date": "1995", "authors": "Schoenherr CJ, Anderson DJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7871435", "url": "https://glygen.org/publication/PubMed/7871435" } ] }, { "title": "Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Zhu J, Reynet C, Caldwell JS, Kahn CR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7876254", "url": "https://glygen.org/publication/PubMed/7876254" } ] }, { "title": "Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.", "journal": "Cell", "date": "1994", "authors": "Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva AJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "7923378", "url": "https://glygen.org/publication/PubMed/7923378" } ] }, { "title": "Cyclin G is a transcriptional target of the p53 tumor suppressor protein.", "journal": "The EMBO journal", "date": "1994", "authors": "Okamoto K, Beach D", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "7957050", "url": "https://glygen.org/publication/PubMed/7957050" } ] }, { "title": "Two highly homologous members of the ClC chloride channel family in both rat and human kidney.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1994", "authors": "Kieferle S, Fong P, Bens M, Vandewalle A, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8041726", "url": "https://glygen.org/publication/PubMed/8041726" } ] }, { "title": "p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5.", "journal": "Nature", "date": "1994", "authors": "Tsai LH, Delalle I, Caviness VS Jr, Chae T, Harlow E", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8090221", "url": "https://glygen.org/publication/PubMed/8090221" } ] }, { "title": "A brain-specific activator of cyclin-dependent kinase 5.", "journal": "Nature", "date": "1994", "authors": "Lew J, Huang QQ, Qi Z, Winkfein RJ, Aebersold R, Hunt T, Wang JH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8090222", "url": "https://glygen.org/publication/PubMed/8090222" } ] }, { "title": "Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen).", "journal": "The EMBO journal", "date": "1994", "authors": "Steinmeyer K, Lorenz C, Pusch M, Koch MC, Jentsch TJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8112288", "url": "https://glygen.org/publication/PubMed/8112288" } ] }, { "title": "Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans.", "journal": "Science (New York, N.Y.)", "date": "1993", "authors": "Reynet C, Kahn CR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8248782", "url": "https://glygen.org/publication/PubMed/8248782" } ] }, { "title": "The p53-mdm-2 autoregulatory feedback loop.", "journal": "Genes & development", "date": "1993", "authors": "Wu X, Bayle JH, Olson D, Levine AJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "8319905", "url": "https://glygen.org/publication/PubMed/8319905" } ] }, { "title": "Proton-sodium stoichiometry of NhaA, an electrogenic antiporter from Escherichia coli.", "journal": "The Journal of biological chemistry", "date": "1993", "authors": "Taglicht D, Padan E, Schuldiner S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8383669", "url": "https://glygen.org/publication/PubMed/8383669" } ] }, { "title": "Transcriptional activity of the zinc finger protein NGFI-A is influenced by its interaction with a cellular factor.", "journal": "Molecular and cellular biology", "date": "1993", "authors": "Russo MW, Matheny C, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8413279", "url": "https://glygen.org/publication/PubMed/8413279" } ] }, { "title": "Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53.", "journal": "Nature", "date": "1993", "authors": "Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "8479525", "url": "https://glygen.org/publication/PubMed/8479525" } ] }, { "title": "Nerve growth factor induces transcription of NGFIA through complex regulatory elements that are also sensitive to serum and phorbol 12-myristate 13-acetate.", "journal": "Molecular endocrinology (Baltimore, Md.)", "date": "1993", "authors": "DeFranco C, Damon DH, Endoh M, Wagner JA", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8483478", "url": "https://glygen.org/publication/PubMed/8483478" } ] }, { "title": "Spectrum of mutations in the major human skeletal muscle chloride channel gene (CLCN1) leading to myotonia.", "journal": "American journal of human genetics", "date": "1995", "authors": "Meyer-Kleine C, Steinmeyer K, Ricker K, Jentsch TJ, Koch MC", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8533761", "url": "https://glygen.org/publication/PubMed/8533761" } ] }, { "title": "Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.", "journal": "Kidney international", "date": "1995", "authors": "Takeuchi Y, Uchida S, Marumo F, Sasaki S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8544406", "url": "https://glygen.org/publication/PubMed/8544406" } ] }, { "title": "Transcriptional regulation of the tissue factor gene in human epithelial cells is mediated by Sp1 and EGR-1.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Cui MZ, Parry GC, Oeth P, Larson H, Smith M, Huang RP, Adamson ED, Mackman N", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8576248", "url": "https://glygen.org/publication/PubMed/8576248" } ] }, { "title": "Increased expression of early growth response-1 messenger ribonucleic acid in prostatic adenocarcinoma.", "journal": "The Journal of urology", "date": "1996", "authors": "Thigpen AE, Cala KM, Guileyardo JM, Molberg KH, McConnell JD, Russell DW", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8583621", "url": "https://glygen.org/publication/PubMed/8583621" } ] }, { "title": "Cloning and expression of a novel human brain Na+ channel.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Price MP, Snyder PM, Welsh MJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8626462", "url": "https://glygen.org/publication/PubMed/8626462" } ] }, { "title": "Rac GTPase interacts specifically with phosphatidylinositol 3-kinase.", "journal": "The Biochemical journal", "date": "1996", "authors": "Bokoch GM, Vlahos CJ, Wang Y, Knaus UG, Traynor-Kaplan AE", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "8645157", "url": "https://glygen.org/publication/PubMed/8645157" } ] }, { "title": "NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.", "journal": "Molecular and cellular biology", "date": "1996", "authors": "Svaren J, Sevetson BR, Apel ED, Zimonjic DB, Popescu NC, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8668170", "url": "https://glygen.org/publication/PubMed/8668170" } ] }, { "title": "Activation of codependent transcription factors is required for transcriptional induction of the vgf gene by nerve growth factor and Ras.", "journal": "Molecular and cellular biology", "date": "1996", "authors": "D'Arcangelo G, Habas R, Wang S, Halegoua S, Salton SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8756618", "url": "https://glygen.org/publication/PubMed/8756618" } ] }, { "title": "The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis.", "journal": "The Biochemical journal", "date": "1996", "authors": "Tunwell RE, Wickenden C, Bertrand BM, Shevchenko VI, Walsh MB, Allen PD, Lai FA", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "8809036", "url": "https://glygen.org/publication/PubMed/8809036" } ] }, { "title": "The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.", "journal": "Genes & development", "date": "1996", "authors": "Nikolic M, Dudek H, Kwon YT, Ramos YF, Tsai LH", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8846918", "url": "https://glygen.org/publication/PubMed/8846918" } ] }, { "title": "p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A.", "journal": "Molecular and cellular biology", "date": "1996", "authors": "Okamoto K, Kamibayashi C, Serrano M, Prives C, Mumby MC, Beach D", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "8887688", "url": "https://glygen.org/publication/PubMed/8887688" } ] }, { "title": "The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation.", "journal": "Molecular and cellular neurosciences", "date": "1996", "authors": "Zorick TS, Syroid DE, Arroyo E, Scherer SS, Lemke G", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "8918830", "url": "https://glygen.org/publication/PubMed/8918830" } ] }, { "title": "Structure and chromosomal assignment of the human cyclin G gene.", "journal": "Genomics", "date": "1996", "authors": "Endo Y, Fujita T, Tamura K, Tsuruga H, Nojima H", "evidence": [ { "database": "Reactome", "id": "R-HSA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757" } ], "reference": [ { "type": "PubMed", "id": "8954786", "url": "https://glygen.org/publication/PubMed/8954786" } ] }, { "title": "Interplay of the E box, the cyclic AMP response element, and HTF4/HEB in transcriptional regulation of the neurospecific, neurotrophin-inducible vgf gene.", "journal": "Molecular and cellular biology", "date": "1997", "authors": "Di Rocco G, Pennuto M, Illi B, Canu N, Filocamo G, Trani E, Rinaldi AM, Possenti R, Mandolesi G, Sirinian MI, Jucker R, Levi A, Nasi S", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9032251", "url": "https://glygen.org/publication/PubMed/9032251" } ] }, { "title": "BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1997", "authors": "Garcia-Anoveros J, Derfler B, Neville-Golden J, Hyman BT, Corey DP", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9037075", "url": "https://glygen.org/publication/PubMed/9037075" } ] }, { "title": "Molecular cloning and characterization of the human VGF promoter region.", "journal": "Journal of neurochemistry", "date": "1997", "authors": "Canu N, Possenti R, Rinaldi AM, Trani E, Levi A", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9084409", "url": "https://glygen.org/publication/PubMed/9084409" } ] }, { "title": "Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1997", "authors": "Waldegger S, Barth P, Raber G, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "9114008", "url": "https://glygen.org/publication/PubMed/9114008" } ] }, { "title": "Role of cyclins in neuronal differentiation of immortalized hippocampal cells.", "journal": "Molecular and cellular biology", "date": "1997", "authors": "Xiong W, Pestell R, Rosner MR", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9343422", "url": "https://glygen.org/publication/PubMed/9343422" } ] }, { "title": "CREB: a major mediator of neuronal neurotrophin responses.", "journal": "Neuron", "date": "1997", "authors": "Finkbeiner S, Tavazoie SF, Maloratsky A, Jacobs KM, Harris KM, Greenberg ME", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9390517", "url": "https://glygen.org/publication/PubMed/9390517" } ] }, { "title": "Molecular cloning and characterization of a human brain ryanodine receptor.", "journal": "FEBS letters", "date": "1997", "authors": "Nakashima Y, Nishimura S, Maeda A, Barsoumian EL, Hakamata Y, Nakai J, Allen PD, Imoto K, Kita T", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9395096", "url": "https://glygen.org/publication/PubMed/9395096" } ] }, { "title": "Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Swirnoff AH, Apel ED, Svaren J, Sevetson BR, Zimonjic DB, Popescu NC, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9418898", "url": "https://glygen.org/publication/PubMed/9418898" } ] }, { "title": "Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis.", "journal": "Biochemical and biophysical research communications", "date": "1998", "authors": "Ishibashi K, Marumo F", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9571199", "url": "https://glygen.org/publication/PubMed/9571199" } ] }, { "title": "Expression of early growth response genes in human prostate cancer.", "journal": "Cancer research", "date": "1998", "authors": "Eid MA, Kumar MV, Iczkowski KA, Bostwick DG, Tindall DJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9622090", "url": "https://glygen.org/publication/PubMed/9622090" } ] }, { "title": "Identification of the gene responsible for Best macular dystrophy.", "journal": "Nature genetics", "date": "1998", "authors": "Petrukhin K, Koisti MJ, Bakall B, Li W, Xie G, Marknell T, Sandgren O, Forsman K, Holmgren G, Andreasson S, Vujic M, Bergen AA, McGarty-Dugan V, Figueroa D, Austin CP, Metzker ML, Caskey CT, Wadelius C", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9662395", "url": "https://glygen.org/publication/PubMed/9662395" } ] }, { "title": "Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best's disease).", "journal": "Human molecular genetics", "date": "1998", "authors": "Marquardt A, Stohr H, Passmore LA, Kramer F, Rivera A, Weber BH", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9700209", "url": "https://glygen.org/publication/PubMed/9700209" } ] }, { "title": "Amiloride-sensitive Na channels.", "journal": "Current opinion in cell biology", "date": "1998", "authors": "Horisberger JD", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9719863", "url": "https://glygen.org/publication/PubMed/9719863" } ] }, { "title": "The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells.", "journal": "The Journal of cell biology", "date": "1998", "authors": "Qu Z, Wolfraim LA, Svaren J, Ehrengruber MU, Davidson N, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9722618", "url": "https://glygen.org/publication/PubMed/9722618" } ] }, { "title": "Genomic organization and chromosomal localization of the human SGK protein kinase gene.", "journal": "Genomics", "date": "1998", "authors": "Waldegger S, Erdel M, Nagl U O, Barth P, Raber G, Steuer S, Utermann G, Paulmichl M, Lang F", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "reference": [ { "type": "PubMed", "id": "9722955", "url": "https://glygen.org/publication/PubMed/9722955" } ] }, { "title": "Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1998", "authors": "Delcommenne M, Tan C, Gray V, Rue L, Woodgett J, Dedhar S", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "9736715", "url": "https://glygen.org/publication/PubMed/9736715" } ] }, { "title": "Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel.", "journal": "FEBS letters", "date": "1998", "authors": "de Weille JR, Bassilana F, Lazdunski M, Waldmann R", "evidence": [ { "database": "Reactome", "id": "R-HSA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351" } ], "reference": [ { "type": "PubMed", "id": "9744806", "url": "https://glygen.org/publication/PubMed/9744806" } ] }, { "title": "Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1998", "authors": "De Cesare D, Jacquot S, Hanauer A, Sassone-Corsi P", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9770464", "url": "https://glygen.org/publication/PubMed/9770464" } ] }, { "title": "Novel mutants of NAB corepressors enhance activation by Egr transactivators.", "journal": "The EMBO journal", "date": "1998", "authors": "Svaren J, Sevetson BR, Golda T, Stanton JJ, Swirnoff AH, Milbrandt J", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9774344", "url": "https://glygen.org/publication/PubMed/9774344" } ] }, { "title": "Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites.", "journal": "Neuron", "date": "1998", "authors": "Steward O, Wallace CS, Lyford GL, Worley PF", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9808461", "url": "https://glygen.org/publication/PubMed/9808461" } ] }, { "title": "Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "1998", "authors": "Paglini G, Pigino G, Kunda P, Morfini G, Maccioni R, Quiroga S, Ferreira A, Caceres A", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9822744", "url": "https://glygen.org/publication/PubMed/9822744" } ] }, { "title": "Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins.", "journal": "Brain research. Brain research reviews", "date": "1998", "authors": "Herdegen T, Leah JD", "evidence": [ { "database": "Reactome", "id": "R-HSA-9031628", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628" } ], "reference": [ { "type": "PubMed", "id": "9858769", "url": "https://glygen.org/publication/PubMed/9858769" } ] }, { "title": "Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.", "journal": "The Biochemical journal", "date": "1999", "authors": "Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J", "evidence": [ { "database": "Reactome", "id": "R-HSA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604" } ], "reference": [ { "type": "PubMed", "id": "9895304", "url": "https://glygen.org/publication/PubMed/9895304" } ] } ], "pathway": [ { "id": "hsa:6446", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:6446", "resource": "KEGG Pathway" }, { "id": "R-HSA-1257604", "name": "PIP3 activates AKT signaling", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-HSA-2672351", "name": "Stimuli-sensing channels", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-HSA-6804757", "name": "Regulation of TP53 Degradation", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6804757", "resource": "Reactome", "description": "Regulation of TP53 Degradation" }, { "id": "R-HSA-8986944", "name": "Transcriptional Regulation by MECP2", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8986944", "resource": "Reactome", "description": "Transcriptional Regulation by MECP2" }, { "id": "R-HSA-9031628", "name": "NGF-stimulated transcription", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9031628", "resource": "Reactome", "description": "NGF-stimulated transcription" } ], "orthologs": [ { "uniprot_canonical_ac": "Q06226-1", "protein_name": "Serine/threonine-protein kinase Sgk1", "gene_name": "Sgk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVKTEAARSTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKLANNSYACKHPEVQSYLKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPMDSFL", "length": 430 }, "evidence": [ { "id": "45921118", "url": "http://www.informatics.jax.org/homology/45921118", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WVC6-1", "protein_name": "Serine/threonine-protein kinase Sgk1", "gene_name": "Sgk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVKAEAARSTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSHPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVDSFL", "length": 431 }, "evidence": [ { "id": "45921118", "url": "http://www.informatics.jax.org/homology/45921118", "database": "MGI" }, { "id": "O00141", "url": "https://omabrowser.org/oma/group/O00141/", "database": "OMA" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "chloride channel regulator activity", "id": "GO:0017081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017081", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "protein serine/threonine/tyrosine kinase activity", "id": "GO:0004712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004712", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "phosphorylation", "id": "GO:0016310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016310", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of gastric acid secretion", "id": "GO:0060453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060453", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of signal transduction by p53 class mediator", "id": "GO:1901796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901796", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of catalytic activity", "id": "GO:0050790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050790", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "cellular response to aldosterone", "id": "GO:1904045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904045", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "regulation of DNA-binding transcription factor activity", "id": "GO:0051090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051090", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "positive regulation of transporter activity", "id": "GO:0032411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032411", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" }, { "name": "renal sodium ion absorption", "id": "GO:0070294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070294", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Regulated by phosphorylation (PubMed:10191262, PubMed:11096081, PubMed:18925875, PubMed:20338997, PubMed:36373794). Activated by phosphorylation on Ser-422 by mTORC2, transforming it into a substrate for PDPK1 which phosphorylates it on Thr-256 (PubMed:10191262, PubMed:18925875, PubMed:20338997, PubMed:36373794). Phosphorylation on Ser-397 and Ser-401 are also essential for its activity (PubMed:19068477). Phosphorylation on Ser-78 by MAPK7 is required for growth factor-induced cell cycle progression (PubMed:11254654).", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "10191262", "url": "https://glygen.org/publication/PubMed/10191262" }, { "database": "PubMed", "id": "11254654", "url": "https://glygen.org/publication/PubMed/11254654" }, { "database": "PubMed", "id": "19068477", "url": "https://glygen.org/publication/PubMed/19068477" }, { "database": "PubMed", "id": "11096081", "url": "https://glygen.org/publication/PubMed/11096081" }, { "database": "PubMed", "id": "18925875", "url": "https://glygen.org/publication/PubMed/18925875" }, { "database": "PubMed", "id": "20338997", "url": "https://glygen.org/publication/PubMed/20338997" }, { "database": "PubMed", "id": "36373794", "url": "https://glygen.org/publication/PubMed/36373794" } ] }, { "annotation": "Ubiquitinated by NEDD4L; which promotes proteasomal degradation. Ubiquitinated by SYVN1 at the endoplasmic reticulum; which promotes rapid proteasomal degradation and maintains a high turnover rate in resting cells. Isoform 2 shows enhanced stability.", "evidence": [ { "database": "UniProtKB", "id": "O00141", "url": "https://www.uniprot.org/uniprot/O00141" }, { "database": "PubMed", "id": "15576372", "url": "https://glygen.org/publication/PubMed/15576372" } ] } ], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B2DD29-1", "D3ZML2-1", "O08875-1", "O35831-1", "D3ZHP7-1", "D4A280-1", "E9PTG8-1", "O35832-1", "O54748-1", "P57760-1", "Q62868-1", "D3ZBE5-1", "P59895-1", "O55099-1", "O88764-1", "P59241-1", "Q91XS8-1", "Q63644-1", "Q7TQP6-1", "Q9Z2P5-1", "P11345-1", "P11275-1", "F1LYY7-1", "Q9JIH7-1", "P14056-1", "P35426-1", "P51952-1", "P63086-1", "Q5U2X5-1", "Q5XIT0-1", "Q63117-1", "F1M7Y5-1", "P47196-1", "P47197-1", "P97874-1", "Q03114-1", "Q3MJK5-1", "Q09137-1", "Q4V8A3-1", "P54645-1", "Q63686-1", "P08413-1", "P0C1X8-1", "P19139-1", "D4A7V9-1", "Q63184-1", "Q63484-1", "Q9Z1Z1-1", "Q4KM34-1", "Q4KM47-1", "O08874-1", "O70444-1", "O88831-1", "P0C0R5-1", "P26794-1", "P46892-1", "Q66HE7-1", "Q6XUX2-1", "Q62915-1", "Q63185-1", "Q63470-1", "Q62673-1", "Q63433-1", "P53669-1", "P53670-1", "Q63699-1", "Q641Z4-1", "Q91ZN7-1", "A0A0G2K344-1", "P18265-1", "P39951-1", "B2GUY1-1", "B0LT89-1", "A1A5Q6-1", "F1LP90-1", "O08815-1", "O88850-1", "P00539-1", "P0C865-1", "P27791-1", "P63319-1", "P68182-1", "P97924-1", "Q01986-1", "Q06226-1", "Q53UA7-1", "Q62862-1", "Q63454-1", "Q63531-1", "Q63562-1", "Q63572-1", "Q64617-1", "Q66HA1-1", "Q7TNL4-1", "P09215-1", "O55173-1", "O70150-1", "P05696-1", "P09216-1", "P11730-1", "P13234-1", "P15791-1", "P68403-1", "P97633-1", "P97756-1", "Q62761-1", "Q62762-1", "Q62763-1", "B1WBU5-1", "D3ZGQ5-1", "D4AE59-1", "F1M0Z1-1", "P13286-1", "P49187-1", "Q5RKH1-1", "Q62829-1", "Q63638-1", "Q9JLS3-1", "Q9JM01-1", "Q9R011-1", "Q9R012-1", "D3ZSZ3-1", "Q06486-1", "Q62726-1", "Q63450-1", "Q4KSH7-1", "Q5XIS9-1", "Q63285-1", "Q63553-1", "P67999-1", "O88664-1", "O08678-1", "O08679-1", "Q99J82-1", "Q7TNJ7-1", "Q64303-1", "Q66HE5-1", "Q7TPK6-1", "Q64595-1", "P49185-1", "P09217-1", "P36506-1", "P35465-1", "P20793-1", "O88506-1", "Q9Z335-1", "Q8R4U9-1", "Q8R4V0-1", "Q924U5-1", "Q9WTQ1-1", "Q9Z2A6-1", "D3ZG83-1", "P21708-1", "P27704-1", "Q4V793-1", "Q5MPA9-1", "Q5U2N4-1", "Q62925-1", "Q63538-1", "Q66H84-1", "Q9WTY9-1", "O54874-1", "Q8VHF0-1", "P42346-1", "P49186-1", "Q4G050-1", "P70618-1", "Q925B3-1", "Q63796-1", "Q7TT49-1", "Q810W7-1", "Q924I2-1", "Q9R1U5-1", "Q9WTQ0-1", "P0C8E4-1", "P18266-1", "D4AE24-1", "D3ZSB7-1", "A4L9P5-1", "D4A6T9-1", "E9PSL7-1", "F1LXF1-1", "D3Z822-1", "A0A8I6AQN6-1", "D3Z8E0-1", "F1M7N7-1", "A0A8I6AWX7-1", "Q9QY78-1", "E9PSK5-1", "A0A0G2JZW9-1", "A0A0G2KB60-1", "D3ZHL6-1", "Q63945-1", "F1LNN8-1", "A0A0G2K5L3-1", "F7FMK8-1", "A0A8I5ZMP0-1", "M0RD40-1", "A0A0G2JVL3-1", "F1LRA7-1", "A0A8I5ZP97-1", "D3Z837-1", "D3ZL21-1", "A0A8I6AUJ4-1", "F1M7G0-1", "D4A355-1", "D4A454-1", "D3ZCD7-1", "D3ZFL3-1", "D3ZXB1-1", "A0A8I5ZZZ6-1", "A0A0G2JUP3-1", "D3Z8I4-1", "A0A8I5ZNK2-1", "D3ZRJ7-1", "D4AD76-1", "F1M419-1", "A0A8I6ANX6-1", "A0A8I6A165-1", "B5DFG1-1", "A0A8I6A0F8-1", "F1LNJ1-1", "A0A8I6AEL0-1", "A0A8I6ATH0-1", "D3ZTD1-1", "M0RBT0-1", "A0A8I5Y8C3-1", "A0A8I6GK52-1", "D4A6T6-1", "A0A8I6ATM1-1", "A0A8I6G1H3-1", "D3ZMG0-1", "F1LUY7-1", "A0A8I6A7D1-1", "A0A8J8XEH6-1", "A0A8I6AD01-1", "A0A8I6AJX5-1", "A6KB61-1", "Q9Z1L0-1", "G3V783-1", "Q6V9V9-1", "A0A8I5ZUS1-1", "A0A0G2K578-1", "A0A0G2K6V9-1", "D4A9H8-1", "D3ZJ84-1", "A0A8I5ZV60-1", "B1WBT4-1", "A0A8I6A574-1", "Q4KLN3-1", "A0A8I6AHQ6-1", "A0A0G2K5C7-1", "M0RDM0-1", "Q6V9Y3-1", "M0R777-1", "D3ZDM6-1", "D3ZD18-1", "Q5PQT0-1", "Q6V9Y2-1", "D3ZQN8-1", "F1LWF2-1", "F1M9D0-1", "A0A8I5ZUX6-1", "A0A8I5ZT61-1", "A0A8I5ZN46-1", "A0A8I5Y7S3-1", "A0A0G2K2T8-1", "A0A0G2JWX7-1", "A0A0G2JXR8-1", "D3ZSY9-1", "D4A3H8-1", "D4A3D9-1", "D3ZZK7-1", "A0A8I5ZLV4-1", "A0A0G2KAH6-1", "A0A0G2QC55-1", "A0A8I5ZR62-1", "A0A8I6A1U5-1", "A0A8I6A8U4-1", "A0A8I6A9X0-1", "A0A8I6ACE8-1", "D3ZBS8-1", "A0A8I6GI15-1", "D3ZEK4-1", "A0A8I6GM03-1", "Q4KSH6-1", "F1LWJ6-1", "F1LTP9-1", "E9PSM2-1", "M0RD88-1", "D4A949-1", "A0A8I6A7V5-1", "A0A8I5ZSS7-1", "A0A8I6GBQ0-1", "A0A8I6AAX5-1", "A0A8I6ACR1-1", "A0A8I6GDY5-1", "A0A8I6GJV1-1", "A0A8I6G980-1", "A0A8I5ZS27-1", "A0A8I5ZYM4-1", "A6HK01-1", "A0A0G2K490-1", "M0R7E7-1", "A0A8I6AJD2-1", "A0A8I6GK16-1", "A0A8I6GKS8-1", "A0A8I6G5Z0-1", "Q925D6-1", "Q00972-1", "A0A8I5ZKJ9-1", "Q9HCP0-1", "P0C263-1", "Q6ZMQ8-1", "Q2M2I8-1", "P31751-1", "Q07912-1", "Q5VT25-1", "O43293-1", "P53779-1", "Q9P0L2-1", "Q13164-1", "P21127-1", "Q9BWU1-1", "Q9UQ88-1", "Q00537-1", "Q8IZL9-1", "Q9UQB9-1", "Q8IWQ3-1", "Q9NYV4-1", "Q13315-1", "Q96GD4-1", "P06493-1", "Q00526-1", "O60566-1", "O76039-2", "O94921-1", "Q00535-1", "Q8IVW4-1", "Q9Y243-1", "Q07002-2", "P50613-1", "Q92772-1", "P10398-1", "Q8NFD2-1", "O43683-1", "O14965-1", "P24941-1", "Q15131-1", "Q9NSY1-1", "P33076-1", "Q86TB3-1", "P50750-1", "Q14004-1", "P11802-1", "Q8TDC3-1", "O00311-1", "Q00536-1", "P11274-1", "P49336-1", "Q96QP1-1", "Q96L96-1", "Q13131-1", "P31749-1", "Q13535-1", "P54646-1", "O96017-1", "P49760-1", "Q5MAI5-1", "Q00532-1", "Q00534-1", "P49761-4", "Q9HAZ1-1", "P49759-1", "Q96Q40-1", "P41279-1", "P15056-1", "O14757-1", "P68400-1", "Q6XUX3-1", "Q9Y463-1", "Q76MJ5-1", "Q9P2K8-1", "P19525-1", "Q8N568-1", "Q09013-9", "Q9NR20-1", "Q9NZJ5-1", "O15075-1", "Q9C098-1", "O14578-1", "P53355-1", "O14936-1", "Q8IXL6-1", "Q13627-1", "Q9Y4B6-1", "Q9BQI3-1", "Q9UIK4-1", "Q92630-1", "Q8NEV1-1", "O43781-1", "O75460-1", "P19784-1", "Q13557-1", "Q13976-1", "P17252-1", "P41743-1", "Q15418-1", "P51617-1", "Q15349-1", "Q9UQM7-1", "Q13554-1", "Q9NRM7-1", "O95835-1", "Q9H2X6-1", "P49674-1", "Q86Z02-1", "Q16566-1", "Q6P2M8-1", "P78368-1", "Q96NX5-1", "Q9Y6M4-1", "P22612-1", "P57058-1", "Q9H422-1", "Q9NWZ3-1", "Q8IWU2-1", "Q8N5S9-1", "O14976-1", "Q8NE63-1", "Q13555-1", "Q96RR4-1", "Q15139-1", "P11801-1", "O94806-1", "Q13237-1", "Q96S38-1", "Q9UK32-1", "Q8N752-1", "Q14012-1", "P05129-1", "Q9UBS0-1", "O60229-1", "P51812-1", "P05771-1", "Q05655-1", "Q02156-1", "P53667-1", "Q9UPZ9-1", "Q13418-1", "P23443-1", "Q8TF76-1", "Q04759-1", "Q9BZL6-1", "Q05513-1", "Q6VAB6-1", "P49840-1", "P49841-1", "P48730-1", "O75676-1", "O75582-1", "P24723-1", "Q8IVT5-1", "Q8IU85-1", "Q96GX5-1", "P22694-1", "P48729-1", "P17612-1", "Q16659-1", "Q02750-1", "O14733-1", "Q8TD08-1", "Q9Y2U5-1", "Q6P0Q8-1", "P46734-1", "P51957-1", "Q6DT37-1", "Q5VST9-1", "Q9Y5S2-1", "Q9UQ07-1", "P28482-1", "P00540-1", "O75914-1", "Q99759-1", "Q99558-1", "P51955-1", "Q8IW41-1", "Q9Y6R4-1", "P51956-1", "Q6P3R8-1", "Q13163-1", "Q13233-1", "O60307-1", "Q56UN5-1", "O95382-1", "Q02779-1", "O15021-5", "P45985-1", "Q86SG6-1", "Q6ZWH5-1", "Q86YV6-1", "Q8WXR4-1", "Q8NEV4-1", "Q6A1A2-1", "P80192-1", "P31152-1", "O15264-1", "P52564-1", "Q96QS6-1", "O60285-1", "Q7Z2Y5-1", "Q15759-1", "P49137-1", "Q16644-1", "Q96L34-1", "P53778-1", "Q9UBE8-1", "O95819-1", "Q8N4C8-1", "P36507-1", "Q96Q04-1", "P53671-1", "Q8NG66-1", "Q9Y4K4-1", "Q9HBH9-1", "Q96PY6-1", "Q9H093-1", "O43318-1", "Q16584-1", "Q7KZI7-1", "Q9BUB5-1", "Q8IY84-1", "P45984-1", "Q99683-1", "O43283-1", "Q12852-1", "Q16539-1", "Q38SD2-1", "Q92918-1", "Q9Y2H9-1", "Q8TD19-1", "Q5TCX8-1", "Q9NYL2-1", "P20794-1", "Q8IVH8-1", "Q12851-1", "Q14680-1", "P45983-1", "Q13153-1", "Q5S007-1", "Q6ZN16-1", "P42345-1", "P27448-5", "P27361-1", "Q9NYY3-1", "Q96RG2-1", "Q9Y6S9-1", "Q15772-5", "Q16816-1", "Q16513-1", "Q99570-1", "Q86V86-1", "Q16512-1", "P57059-1", "Q9BXM7-1", "Q13464-1", "Q9P286-1", "Q8N165-1", "Q99640-1", "P57078-1", "O14730-1", "O96013-1", "Q9H4B4-1", "O43930-1", "Q13523-1", "Q9HBY8-2", "O75116-1", "Q52WX2-1", "O00141-1", "P0C264-1", "Q96BR1-1", "Q9P1W9-1", "Q6P5Z2-1", "Q96LW2-1", "O15530-1", "Q9NQU5-1", "Q13177-1", "Q9BRS2-1", "P48736-1", "P11309-1", "Q13546-1", "Q9NRH2-1", "Q9H0K1-1", "P42336-1", "P51817-1", "P04049-1", "O00444-1", "P78527-1", "Q96Q15-1", "Q96S44-1", "Q9Y572-1", "Q9BVS4-1", "O43353-1", "P53350-1", "O95747-1", "O00506-1", "Q15208-1", "Q8N2I9-1", "Q9BXU1-1", "Q9BYT3-1", "Q9UEE5-1", "Q9UEW8-1", "O94768-1", "Q8TDR2-1", "Q9BX84-1", "Q96QT4-1", "Q96KB5-1", "A0A0B4J2F2-1", "Q9NRP7-1", "P78362-1", "Q9BXA7-1", "O75385-1", "Q5TCY1-1", "Q9Y3S1-1", "Q8WZ42-1", "O75716-1", "Q13188-1", "Q13043-1", "Q96PN8-1", "Q9Y2H1-1", "O75962-1", "Q9UPE1-1", "Q15569-1", "Q8IYT8-1", "Q6PHR2-1", "Q96C45-1", "Q9H2K8-1", "Q9Y6E0-1", "Q9H2G2-1", "Q96S53-1", "P21675-2", "Q7L7X3-1", "Q9UL54-1", "Q9UKE5-1", "Q96SB4-2", "Q15831-1", "Q96J92-1", "Q9BXA6-1", "Q96PF2-1", "Q59H18-2", "Q6SA08-1", "Q6IQ55-1", "Q8TAS1-1", "P33981-1", "Q99986-1", "O94804-1", "Q9P289-1", "Q8WU08-1", "Q9NY57-1", "Q86UX6-1", "Q9UKI8-1", "Q86UE8-1", "Q86Y07-1", "Q9BYP7-1", "Q9Y2K2-5", "Q9H4A3-1", "Q9UHD2-1", "Q9HC98-1", "Q8TDX7-1", "Q9Y2I7-1", "O14920-1", "P42338-1", "Q14296-1", "O14874-1", "Q5SYL1-1", "E9Q3S4-1", "Q62070-1", "Q91Y86-1", "Q9Z188-1", "Q9JKK8-1", "Q8R4K2-1", "Q05512-1", "Q66L42-1", "Q9Z1B7-1", "Q8C050-1", "Q3UHJ0-1", "Q7TT50-1", "O70405-1", "Q61831-1", "Q99MQ3-1", "P49025-1", "Q03141-1", "Q9Z0R0-1", "Q69ZM6-1", "Q9WVS8-1", "Q9WVC6-1", "P04627-1", "Q60823-1", "O54967-1", "Q924C5-1", "Q8BRK8-1", "Q91ZB0-1", "P31750-1", "Q5EG47-1", "O88445-1", "Q5RJI5-1", "Q9Z1S0-1", "O08901-1", "P49615-1", "Q04899-1", "Q3TZA2-1", "Q8BLF2-1", "Q8R3L8-1", "Q9WUA6-1", "P24788-1", "O35495-1", "Q14AX6-1", "Q3UMM4-1", "Q64261-1", "Q8BWD8-1", "Q3UTQ8-1", "Q8CEQ0-1", "Q03147-1", "Q8K0D0-1", "Q8BZ25-1", "O35491-1", "O35493-1", "Q9Z265-1", "Q69ZA1-1", "Q80YP0-1", "Q9JHU3-1", "Q9QUK0-1", "P11440-1", "Q62388-1", "Q91Z96-1", "O35280-1", "O35492-1", "P28028-3", "Q99J95-1", "P30285-1", "P97377-1", "Q9Z0H0-1", "O70126-1", "O70589-1", "P97477-1", "P79621-1", "Q04735-1", "Q3V3A1-1", "Q69Z98-1", "Q6PAJ1-1", "Q9CXB8-1", "P22518-1", "P54265-1", "Q6XUX1-1", "Q03963-1", "O54833-1", "Q80TR8-1", "Q60737-1", "Q80YE7-1", "Q8BWQ5-1", "Q9JLM8-1", "Q6PGN3-1", "Q99KY4-1", "Q61214-1", "Q8VDF3-1", "Q922Y0-1", "O54784-1", "Q9EQY0-1", "Q8BI55-1", "Q9Z2E3-1", "Q5U4C9-1", "Q5MJS3-1", "Q9Z2R9-1", "Q9QZ05-1", "Q9Z2B5-1", "Q91YS8-1", "P68404-1", "Q91YA2-1", "P68181-1", "Q7TPS0-1", "Q8BTH8-1", "Q8C4X2-1", "Q8K1Y2-1", "P16054-1", "P28867-1", "O88904-1", "Q9ERH7-1", "Q3V016-1", "Q8BVP5-1", "Q8BW96-1", "Q9QYK9-1", "P08414-1", "Q8C078-1", "P53349-1", "Q3U1V8-1", "Q80XI6-1", "Q80YE4-1", "Q3TYD6-1", "O08648-1", "Q07174-1", "Q1HKZ5-1", "Q61083-1", "Q3U214-1", "Q8VBY2-1", "P49138-1", "Q02111-1", "P53668-1", "Q9Z2B9-1", "P70218-1", "Q62406-1", "Q61084-1", "O88866-1", "Q61410-1", "P20444-1", "Q62074-1", "Q9WUT3-1", "P0C605-1", "P23298-1", "P63318-1", "P18653-1", "Q8BLK9-1", "Q9WUL6-1", "Q9Z1M4-1", "Q8C0P0-1", "P28652-1", "Q8BZ03-1", "Q60700-1", "Q61161-1", "Q923T9-1", "Q91VB2-1", "Q8VHJ5-1", "Q9QZR5-1", "O55222-1", "Q9JMK2-1", "O54785-1", "O35099-1", "O54992-1", "Q5S006-1", "P18654-1", "Q8BSK8-1", "Q8CIP4-1", "Q811L6-1", "Q8BPM2-1", "Q62101-1", "A2CG49-1", "Q6PHZ2-1", "Q62073-1", "Q8BYR2-1", "Q9R1L5-1", "Q9WTR2-1", "A2AQW0-1", "Q8VDG6-1", "P11798-1", "Q02956-1", "Q04859-1", "Q99JP0-1", "P97820-1", "Q2NL51-1", "Q61097-1", "Q3UHC2-1", "Q3UVC0-1", "Q5XJV6-1", "Q60592-1", "Q7TSJ6-1", "Q9DC28-1", "Q9JKV2-1", "Q9ESL4-1", "Q8BK63-1", "Q9WV60-1", "P05132-1", "P63085-1", "P31938-1", "Q9WVS7-1", "P00536-1", "Q3UMW7-1", "Q61532-1", "Q61846-1", "Q6P5G0-1", "Q1EG27-1", "Q8K3H5-1", "Q5SUV5-1", "Q9Z2A0-1", "Q8VD65-1", "Q8C015-1", "P47809-1", "Q3UU96-1", "P70236-1", "Q91ZR4-1", "Q7TSC3-1", "Q9R0A5-1", "Q641K5-1", "Q9R0G8-1", "Q3ULB5-1", "Q61036-1", "Q8BTW9-1", "Q8CEE6-1", "P58750-1", "P06803-1", "P53351-1", "Q60806-1", "Q8K045-1", "P07934-1", "P70268-1", "O08911-1", "Q63844-1", "Q80Y86-1", "Q9WUI1-1", "O35942-1", "Q8QZR7-1", "Q8BWW9-1", "Q8K1R7-1", "Q63932-1", "Q8BHI9-1", "O09110-1", "O54949-1", "P42337-1", "Q8CE90-1", "Q8C0Q4-1", "O08605-1", "A2AAJ9-1", "P47811-1", "Q8CDB0-1", "P51954-1", "Q8CIN4-1", "Q80UW5-1", "Q8BZN4-1", "Q9WVS4-1", "Q9WTU6-1", "Q9Z1J2-1", "Q9JLN9-1", "O88643-1", "Q07832-1", "Q3UGM2-1", "Q9JHG7-1", "Q9JM52-1", "Q6P9R2-1", "Q64702-1", "Q61136-1", "Q922R0-1", "P70336-1", "Q8R2S1-1", "P0C5K0-1", "P0C5K1-1", "Q9Z0G2-1", "Q8C0X8-1", "Q9QYZ4-1", "Q62407-1", "Q8C0V7-1", "O54988-1", "Q9JJ78-1", "Q3UVR3-1", "Q9D2E1-1", "Q6PCN3-1", "Q9ESG9-1", "A2KF29-1", "Q8BKX6-1", "A0AUV4-1", "Q7TSE6-1", "Q9JI10-1", "Q0KL02-1", "Q3U3Q1-1", "Q3V129-1", "Q9QY01-1", "P70335-1", "Q8CFH6-1", "Q9WUN2-1", "Q8QZX0-1", "Q8C0N0-1", "Q9ERE3-1", "Q9QZS5-1", "O88697-1", "Q80ZW0-1", "O55098-1", "Q924X7-1", "Q99KH8-1", "Q99MW1-1", "Q9Z2W1-1", "Q7TNL3-1", "Q91VJ4-1", "Q9JI11-1", "Q9DBU3-1", "Q9ERK0-1", "Q9QYZ6-1", "Q5F2E8-1", "Q6ZQ29-1", "Q8BYC6-1", "Q80UV9-1", "O70146-1", "Q8VCT9-1", "Q9QZL0-1", "Q61241-1", "Q99JT2-1", "Q8QZV4-1", "O54781-1", "O55047-1", "Q99N57-1", "Q60855-1", "Q8C0V0-1", "Q8BGW6-1", "Q8C1R0-1", "A2ASS6-1", "P35761-1", "Q8BG48-1", "C0HKC8-1", "Q9QYZ3-1", "Q922Q2-1", "Q8VDU5-1", "O70551-1", "P97313-1", "P83510-1", "P97343-1", "Q60670-1", "Q5GIG6-1", "Q6P4S6-1", "Q99PW4-1", "Q9CQS5-1", "Q9WTK7-1", "Q9D411-1", "C0HKC9-1", "Q9JJX8-1", "P58801-1", "Q9Z1W9-1", "Q80UE6-1", "Q923J1-1", "Q8CIR4-1", "Q925K9-1", "O54863-1", "Q8BN21-1", "Q80X41-1", "Q80XP9-1", "P83741-1", "Q3UH66-1", "O88351-1", "Q5U452-1", "Q9Z1T6-2", "Q9ES70-1", "Q9ES74-1", "Q9JIX9-1", "Q8BTI9-1", "A2AQX6-1", "J3QK59-1", "Q3UT86-1", "A0A087WRH8-1", "A0A087WSA6-1", "A0A140LI04-1", "Q8BWE1-1", "J3KMT3-1", "A0A087WSF2-1", "Q3UTA8-1", "A0A140LJ87-1", "A0A3B2WD63-1", "O55028-1", "P32490-1", "P13185-1", "P13186-1", "P14680-1", "P15442-1", "P15790-1", "P18961-1", "P19454-1", "P21965-1", "P22204-1", "P22216-1", "P22517-1", "P23292-1", "P23293-1", "P23561-1", "P25333-1", "P25341-1", "P25389-1", "P27466-1", "P27636-1", "P29295-1", "P32600-1", "P32944-1", "P35169-1", "P36003-1", "P38615-1", "P40494-1", "P41695-1", "P43565-1", "P53894-1", "P53974-1", "Q03497-1", "Q12263-1", "P06784-1", "P00546-1", "P05986-1", "P06243-1", "P06244-1", "P06245-1", "P06782-1", "P08018-1", "P08458-1", "P11792-1", "P12688-1", "P14681-1", "P16892-1", "P17157-1", "P22211-1", "P23291-1", "P24583-1", "P32485-1", "P32562-1", "P39009-1", "P40160-1", "P41808-1", "P43568-1", "P48562-1", "P53233-1", "P53739-1", "Q00772-1", "Q03407-1", "P32491-1", "P32581-1", "P28708-1", "P31374-1", "P32328-1", "P32350-1", "P32361-1", "P32789-1", "P32801-1", "P22219-1", "P22209-1", "P24719-1", "P25390-1", "P36002-1", "P36004-1", "P38147-1", "P38622-1", "Q01919-1", "P39073-1", "P38692-1", "P38970-1", "P38990-1", "P38991-1", "P39962-1", "P43633-1", "P47116-1", "P53599-1", "P34244-1", "P36005-1", "P38070-1", "P38080-1", "P38110-1", "P38111-1", "P38623-1", "P38691-1", "P53104-1", "P53323-1", "P54199-1", "Q01389-1", "Q03656-1", "Q08217-1", "Q03306-1", "Q03533-1", "Q03785-1", "Q12003-1", "Q12100-1", "Q12196-1", "Q12236-1", "Q12469-1", "Q12505-1", "P43637-1", "P47042-1", "P50873-1", "Q03002-1", "Q06098-1", "Q08732-1", "Q12152-1", "Q12222-1", "Q12310-1", "Q54HS0-1", "Q54R98-1", "Q54FH3-1", "Q54RP7-1", "Q54P26-1", "Q54PK8-1", "Q54VV7-1", "Q54XZ5-1", "Q54Y90-1", "Q55A09-1", "Q55BA0-1", "Q86HW6-1", "Q54C38-1", "Q54DY0-1", "Q54E34-1", "Q54EM1-1", "Q54ER4-1", "Q54ET3-1", "Q54F40-1", "Q54FR9-1", "Q54G43-1", "Q54H05-1", "Q54HD2-1", "Q54IF2-1", "Q54IH8-1", "Q54IP4-1", "Q54JQ1-1", "Q54L00-1", "Q54L81-1", "Q54LH8-1", "Q54LU8-1", "Q54MH0-1", "Q54MV2-1", "Q54PX0-1", "Q54QD5-1", "Q54R95-1", "Q54RB2-1", "Q54RJ4-1", "Q54RR9-1", "Q54RV3-1", "Q54RZ7-1", "Q54SC4-1", "Q54SK3-1", "Q54TA3-1", "Q54TH6-1", "Q54TN4-1", "Q54U31-1", "Q54U65-1", "Q54UA9-1", "Q54UZ1-1", "Q54V35-1", "Q54V83-1", "Q54VC0-1", "Q54VU4-1", "Q54WC0-1", "Q54WD7-1", "Q54WE5-1", "Q54WW7-1", "Q54XJ4-1", "Q54XX5-1", "Q54XY6-1", "Q54Y06-1", "Q54Y55-1", "Q54YZ5-1", "Q54ZN3-1", "Q552C1-1", "Q552E9-1", "Q552Z2-1", "Q553E9-1", "Q556J6-1", "Q559A2-1", "Q559T8-1", "Q55A55-1", "Q55CA6-1", "Q55CE0-1", "Q55CW2-1", "Q55CW3-1", "Q55DJ9-1", "Q55DK2-1", "Q55DU7-1", "Q55EI8-1", "Q55F45-1", "Q55FJ6-1", "Q55FV4-1", "Q55FV5-1", "Q55GC2-1", "Q55GE6-1", "Q55GG4-1", "Q55GS4-1", "Q55GU0-1", "Q6XHA7-1", "Q75JN1-1", "Q76P07-1", "Q869L4-1", "Q869T7-1", "Q869X3-1", "Q86A12-1", "Q86HG9-1", "Q86I06-1", "Q8MYF1-1", "Q8SSV3-1", "Q9NGW9-1", "P34099-1", "Q1ZXI5-1", "Q54D75-1", "Q54EY4-1", "Q54UL8-1", "Q558U1-1", "Q5VJL3-1", "B0G126-1", "O61122-1", "O61125-1", "P0CD62-1", "P28178-1", "P34100-1", "P34101-1", "P34102-1", "P34103-1", "P34112-1", "P34117-1", "P42525-1", "P54644-1", "P54685-1", "Q02720-1", "Q1ZXC8-1", "Q1ZXD6-1", "Q1ZXH2-1", "Q1ZXR2-1", "Q23915-1", "Q54B33-1", "Q54B48-1", "Q54BC9-1", "Q54BF0-1", "Q54C18-1", "Q54C71-1", "Q54DC8-1", "Q54DF2-1", "Q54DK3-1", "Q54EG9-1", "Q54GY6-1", "Q54H45-1", "Q54H46-1", "Q54HC6-1", "Q54I36-1", "Q54IE8-1", "Q54JC7-1", "Q54JG7-1", "Q54LR6-1", "Q54M77-1", "Q54MY9-1", "Q54P47-1", "Q54PK9-1", "Q54Q69-1", "Q54QB1-1", "Q54QI2-1", "Q54QQ1-1", "Q54QV3-1", "Q54R82-1", "Q54RB7-1", "Q54S77-1", "Q54T05-1", "Q54TA1-1", "Q54TM7-1", "Q54TW2-1", "Q54UC0-1", "Q54VD8-1", "Q54VI1-1", "Q54W07-1", "Q54WJ0-1", "Q54WS5-1", "Q54WX4-1", "Q54XL6-1", "Q54XQ2-1", "Q54Y26-1", "Q54YF2-1", "Q550K8-1", "Q550L8-1", "Q551H4-1", "Q552C6-1", "Q556Q3-1", "Q556S2-1", "Q556Y4-1", "Q557G1-1", "Q55BN8-1", "Q55CL6-1", "Q55CY9-1", "Q55CZ1-1", "Q55D99-1", "Q55DD4-1", "Q55DJ8-1", "Q55E58-1", "Q55EC7-1", "Q55FS2-1", "Q55FT4-1", "Q55GJ2-1", "Q55GV3-1", "Q6B9X6-1", "Q6XHA5-1", "Q6XHB2-1", "Q75JK0-1", "Q76NV1-1", "Q869N2-1", "Q86AE1-1", "Q86AT8-1", "Q86C65-1", "Q86CS2-1", "Q86HN7-1", "Q86IX1-1", "Q8MVR1-1", "Q8SSS9-1", "Q8SSY6-1", "Q8T2I8-1", "Q95YH0-1", "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83098-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "A0A0B4KHX7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "M9PI41-1", "Q9VM90-1", "Q9VXE3-1", "A1ZBH7-1", "Q9W002-1", "P83099-1", "Q9NIV1-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P49762-1", "P54367-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "P54360-1", "Q9VT57-1", "Q9VI13-1", "A1ZBC4-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "Q7PLI7-1", "X2JAG8-1", "O61661-1", "A4VCL2-2", "A0A0B4KHT3-1", "A0A4D6K823-1", "A1ZBL9-1", "Q9VP22-1", "Q9W1B0-1", "Q9V3I5-1", "Q9VRJ6-1", "Q8T9L5-1", "Q94533-1", "Q9VUQ9-1", "Q9VGF9-1", "Q9VBU2-1", "Q9VR42-1", "Q9VL34-1", "Q9VTL5-1", "Q95TN8-1", "Q9VCV0-1", "Q8MSQ4-1", "Q9VE06-1", "Q9VJ30-1", "Q9VXN5-1", "M9PGC5-1", "Q9VN23-1", "M9NGC6-1", "O61444-1", "O62602-1", "Q9VUV4-1", "Q9VMY8-1", "Q9VD82-1", "A0A6M3Q7C8-1", "Q9W3N8-1", "Q95SH0-1", "Q9VI84-1", "Q9VEN3-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B2DD29-1", "D3ZML2-1", "O08875-1", "O35831-1", "P57760-1", "D3ZHP7-1", "D4A280-1", "E9PTG8-1", "O35832-1", "O54748-1", "Q62868-1", "D3ZBE5-1", "P59895-1", "O55099-1", "O88764-1", "P59241-1", "Q91XS8-1", "Q63644-1", "Q7TQP6-1", "Q9Z2P5-1", "P11345-1", "P11275-1", "F1LYY7-1", "Q9JIH7-1", "Q5XIT0-1", "P14056-1", "P35426-1", "P51952-1", "P63086-1", "Q5U2X5-1", "Q63117-1", "F1M7Y5-1", "P08413-1", "P47196-1", "P47197-1", "P97874-1", "Q03114-1", "Q3MJK5-1", "Q09137-1", "Q4V8A3-1", "P54645-1", "Q63686-1", "P0C1X8-1", "P19139-1", "D4A7V9-1", "Q62915-1", "Q63184-1", "Q63484-1", "Q9Z1Z1-1", "O70444-1", "P0C0R5-1", "O08874-1", "O88831-1", "P18265-1", "P26794-1", "P46892-1", "Q4KM34-1", "Q4KM47-1", "Q66HE7-1", "Q6XUX2-1", "Q63185-1", "Q63470-1", "Q62673-1", "Q63433-1", "P53669-1", "P53670-1", "Q63699-1", "Q641Z4-1", "Q91ZN7-1", "P39951-1", "B2GUY1-1", "A1A5Q6-1", "B0LT89-1", "F1LP90-1", "O08815-1", "O88850-1", "P00539-1", "P0C865-1", "P27791-1", "P63319-1", "P68182-1", "P97924-1", "Q01986-1", "Q06226-1", "Q53UA7-1", "Q62862-1", "Q63454-1", "Q63531-1", "Q63562-1", "Q63572-1", "Q64617-1", "Q66HA1-1", "Q7TNL4-1", "Q62762-1", "O55173-1", "O70150-1", "P05696-1", "P09216-1", "P11730-1", "P13234-1", "P15791-1", "P68403-1", "P97633-1", "P97756-1", "Q62761-1", "Q62763-1", "D4AE59-1", "B1WBU5-1", "D3ZGQ5-1", "F1M0Z1-1", "P13286-1", "P49187-1", "Q5RKH1-1", "Q62829-1", "Q63638-1", "Q9JLS3-1", "Q9JM01-1", "Q9R011-1", "Q9R012-1", "D3ZSZ3-1", "Q06486-1", "Q62726-1", "Q63450-1", "Q4KSH7-1", "Q5XIS9-1", "Q63285-1", "Q63553-1", "P67999-1", "O88664-1", "O08678-1", "O08679-1", "Q99J82-1", "Q7TNJ7-1", "Q64303-1", "Q66HE5-1", "Q64595-1", "P09215-1", "P49185-1", "P09217-1", "P36506-1", "P35465-1", "P20793-1", "Q7TPK6-1", "O88506-1", "D4A229-1", "Q8R4V0-1", "Q8R4U9-1", "Q924U5-1", "Q9WTQ0-1", "Q9WTQ1-1", "Q9Z2A6-1", "Q9Z335-1", "D3ZG83-1", "P21708-1", "P27704-1", "Q4V793-1", "Q5MPA9-1", "Q5U2N4-1", "Q62925-1", "Q63538-1", "Q66H84-1", "Q9WTY9-1", "O54874-1", "Q8VHF0-1", "A0A0G2JZW9-1", "Q924I2-1", "P42346-1", "P49186-1", "Q4G050-1", "P70618-1", "Q925B3-1", "Q63796-1", "Q7TT49-1", "Q810W7-1", "Q9R1U5-1", "F1LRA7-1", "D3ZHL6-1", "D4A454-1", "D3ZXB1-1", "P0C8E4-1", "P18266-1", "D3Z8I4-1", "D3ZY07-1", "D4AE24-1", "F1M419-1", "D3ZSB7-1", "A0A0G2K5L3-1", "A0A8I6A165-1", "A4L9P5-1", "D4A6T9-1", "E9PSL7-1", "D4ACL8-1", "F1LXF1-1", "D3Z822-1", "A0A8I6AQN6-1", "D3Z8E0-1", "F1M7N7-1", "A0A8I6AWX7-1", "A0A8I5ZZZ6-1", "D3ZMG0-1", "Q9QY78-1", "E9PSK5-1", "A0A0G2KB60-1", "Q63945-1", "F1LNN8-1", "A0A8I5ZMP0-1", "M0RD40-1", "A0A0G2JVL3-1", "A0A8I5ZP97-1", "D3Z837-1", "D3ZL21-1", "A0A8I6AUJ4-1", "F1M7G0-1", "D4A355-1", "D3ZCD7-1", "D3ZFL3-1", "A0A0G2JUP3-1", "A0A8I5ZNK2-1", "D3ZRJ7-1", "D4AD76-1", "A0A8I6ANX6-1", "B5DFG1-1", "A0A8I6A0F8-1", "F1LNJ1-1", "A0A8I6AEL0-1", "A0A8I6G1H3-1", "A0A8I6ATH0-1", "D3ZTD1-1", "M0RBT0-1", "A0A8I5Y8C3-1", "F7FMK8-1", "A0A0G2K578-1", "A0A8I6GK52-1", "D4A6T6-1", "A0A8I6ATM1-1", "F1LUY7-1", "A0A8I6AJD2-1", "M0RDM0-1", "M0RD88-1", "A0A8I6A7D1-1", "A0A8J8XEH6-1", "A0A8I6AD01-1", "A0A8I6AJX5-1", "A6KB61-1", "A0A8I6ACR1-1", "P11980-1", "A0A8I5ZUX6-1", "A0A8I5ZSS7-1", "G3V783-1", "A0A8I6GI15-1", "M0R777-1", "Q6V9V9-1", "A0A8I5ZUS1-1", "A0A0G2K6V9-1", "D4A9H8-1", "D3ZJ84-1", "A0A8I5ZV60-1", "B1WBT4-1", "A0A8I6A574-1", "Q4KLN3-1", "A0A8I6AHQ6-1", "A0A0G2K5C7-1", "Q6V9Y3-1", "D3ZDM6-1", "D3ZD18-1", "Q5PQT0-1", "Q6V9Y2-1", "D3ZQN8-1", "F1LWF2-1", "F1M9D0-1", "A0A8I5ZT61-1", "A0A8I5ZN46-1", "A0A8I5Y7S3-1", "A0A0G2K2T8-1", "A0A0G2JWX7-1", "A0A0G2JXR8-1", "D3ZSY9-1", "D4A3H8-1", "D4A3D9-1", "D3ZZK7-1", "A0A8I5ZLV4-1", "A0A0G2KAH6-1", "A0A0G2QC55-1", "A0A8I5ZR62-1", "A0A8I6A1U5-1", "A0A8I6A8U4-1", "A0A8I6A9X0-1", "A0A8I6ACE8-1", "D3ZBS8-1", "D3ZEK4-1", "A0A8I6GM03-1", "Q4KSH6-1", "F1LWJ6-1", "F1LTP9-1", "E9PSM2-1", "D4A949-1", "A0A8I6A7V5-1", "A0A8I6GBQ0-1", "A0A8I6AAX5-1", "A0A8I6GDY5-1", "A0A8I6GJV1-1", "A0A8I6G980-1", "A0A8I5ZS27-1", "A0A8I5ZYM4-1", "A6HK01-1", "A0A0G2K490-1", "M0R7E7-1", "A0A8I6GK16-1", "A0A8I6GKS8-1", "A0A8I6G5Z0-1", "Q925D6-1", "A0A8I5ZKJ9-1", "Q9HCP0-1", "P0C263-1", "Q6ZMQ8-1", "Q2M2I8-1", "P80192-1", "P31751-1", "Q07912-1", "Q5VT25-1", "O43293-1", "P53779-1", "Q9P0L2-1", "Q13164-1", "Q13131-1", "P21127-1", "Q9BWU1-1", "Q9UQ88-1", "Q00537-1", "Q8IZL9-1", "Q9UQB9-1", "Q8IWQ3-1", "Q9NYV4-1", "Q13315-1", "Q96GD4-1", "P06493-1", "Q00526-1", "O60566-1", "O76039-2", "O94921-1", "Q00535-1", "Q8IVW4-1", "Q9Y243-1", "Q07002-2", "P50613-1", "Q92772-1", "P10398-1", "Q8NFD2-1", "O43683-1", "O14965-1", "P24941-1", "Q15131-1", "Q9NSY1-1", "P33076-1", "Q86TB3-1", "P50750-1", "Q14004-1", "P11802-1", "Q8TDC3-1", "P54646-1", "O00311-1", "Q00536-1", "P11274-1", "P49336-1", "Q96QP1-1", "Q96L96-1", "P31749-1", "Q13535-1", "O96017-1", "P49760-1", "Q5MAI5-1", "Q00532-1", "Q00534-1", "P49761-4", "Q9HAZ1-1", "P49759-1", "Q96Q40-1", "P41279-1", "P15056-1", "O14757-1", "P68400-1", "O14936-1", "Q6XUX3-1", "Q9Y463-1", "Q76MJ5-1", "Q9P2K8-1", "P19525-1", "Q8N568-1", "Q09013-9", "Q9NR20-1", "Q9NZJ5-1", "O15075-1", "Q9C098-1", "O14578-1", "P53355-1", "Q8IXL6-1", "Q13627-1", "Q9Y4B6-1", "Q9BQI3-1", "Q9UIK4-1", "Q92630-1", "Q8NEV1-1", "O43781-1", "O75460-1", "P19784-1", "Q13557-1", "Q13976-1", "P41743-1", "P48729-1", "Q15418-1", "P51617-1", "Q15349-1", "Q9UQM7-1", "Q9NRM7-1", "O95835-1", "Q9H2X6-1", "Q86Z02-1", "Q16566-1", "Q6P2M8-1", "P78368-1", "Q96NX5-1", "Q9Y6M4-1", "P22612-1", "P57058-1", "Q13554-1", "Q9H422-1", "Q9NWZ3-1", "Q8IWU2-1", "Q8N5S9-1", "O14976-1", "Q8NE63-1", "Q13555-1", "Q96RR4-1", "Q15139-1", "P11801-1", "O94806-1", "Q13237-1", "Q96S38-1", "Q9UK32-1", "Q8N752-1", "Q14012-1", "P05129-1", "P51812-1", "Q9UBS0-1", "O60229-1", "Q05655-1", "Q02156-1", "P17252-1", "P05771-1", "P53667-1", "Q9UPZ9-1", "Q13418-1", "P23443-1", "P49674-1", "Q8TF76-1", "Q04759-1", "Q9BZL6-1", "Q05513-1", "Q6VAB6-1", "P49840-1", "P49841-1", "P48730-1", "O75676-1", "O75582-1", "P24723-1", "Q8IVT5-1", "Q8IU85-1", "Q96GX5-1", "P22694-1", "P17612-1", "Q16659-1", "Q9UBE8-1", "Q02750-1", "O14733-1", "Q8TD08-1", "Q9Y2U5-1", "Q6P0Q8-1", "P46734-1", "P51957-1", "Q6ZN16-1", "Q6DT37-1", "Q5VST9-1", "Q9Y5S2-1", "Q9UQ07-1", "P28482-1", "P27361-1", "P00540-1", "O75914-1", "Q99759-1", "Q99558-1", "P51955-1", "Q8IW41-1", "Q9Y6R4-1", "P51956-1", "Q6P3R8-1", "Q13163-1", "Q13233-1", "O60307-1", "Q56UN5-1", "O95382-1", "Q02779-1", "O15021-5", "P45985-1", "Q86SG6-1", "Q6ZWH5-1", "Q86YV6-1", "Q8WXR4-1", "Q8NEV4-1", "Q6A1A2-1", "P31152-1", "O15264-1", "P52564-1", "Q96QS6-1", "O60285-1", "Q7Z2Y5-1", "Q15759-1", "P49137-1", "Q16644-1", "Q96L34-1", "P53778-1", "O95819-1", "Q8N4C8-1", "P36507-1", "Q96Q04-1", "P53671-1", "Q8NG66-1", "Q9Y4K4-1", "Q9HBH9-1", "Q96PY6-1", "Q9H093-1", "O43318-1", "P45983-1", "Q16584-1", "Q7KZI7-1", "Q9BUB5-1", "Q8IY84-1", "P45984-1", "Q99683-1", "O43283-1", "Q12852-1", "Q16539-1", "Q38SD2-1", "Q92918-1", "Q9Y2H9-1", "Q8TD19-1", "Q5TCX8-1", "Q13153-1", "Q9NYL2-1", "P20794-1", "Q8IVH8-1", "Q12851-1", "Q14680-1", "Q5S007-1", "P42345-1", "P27448-5", "Q9NYY3-1", "Q96RG2-1", "Q9Y6S9-1", "Q15772-5", "Q16816-1", "Q16513-1", "Q99570-1", "Q86V86-1", "Q16512-1", "P57059-1", "Q13464-1", "Q9P286-1", "Q8N165-1", "Q99640-1", "P57078-1", "O14730-1", "O43353-1", "O96013-1", "Q9H4B4-1", "O43930-1", "Q13523-1", "Q9HBY8-2", "O75116-1", "Q52WX2-1", "O00141-1", "P0C264-1", "Q96BR1-1", "Q9P1W9-1", "Q6P5Z2-1", "Q96LW2-1", "O15530-1", "Q9NQU5-1", "Q9BRS2-1", "Q13546-1", "P11309-1", "Q9NRH2-1", "Q9H0K1-1", "Q13177-1", "P51817-1", "P04049-1", "O00444-1", "P78527-1", "Q96Q15-1", "Q96S44-1", "Q9Y572-1", "Q9BVS4-1", "Q9BXM7-1", "P53350-1", "O95747-1", "O00506-1", "Q15208-1", "Q8N2I9-1", "Q9BXU1-1", "Q9BYT3-1", "Q9UEE5-1", "O94768-1", "Q8TDR2-1", "Q9BX84-1", "Q96QT4-1", "Q96KB5-1", "A0A0B4J2F2-1", "Q9NRP7-1", "P78362-1", "Q9BXA7-1", "O75385-1", "Q5TCY1-1", "Q9Y3S1-1", "Q8WZ42-1", "O75716-1", "Q13188-1", "Q13043-1", "Q96PN8-1", "Q9Y2H1-1", "O75962-1", "Q9UPE1-1", "Q15569-1", "Q8IYT8-1", "Q6PHR2-1", "Q96C45-1", "Q9H2K8-1", "Q9Y6E0-1", "Q9H2G2-1", "Q96S53-1", "P21675-2", "Q7L7X3-1", "Q9UL54-1", "Q9UKE5-1", "Q96SB4-2", "Q9UEW8-1", "Q15831-1", "Q9BXA6-1", "Q96PF2-1", "Q59H18-2", "Q6SA08-1", "Q6IQ55-1", "Q8TAS1-1", "P33981-1", "Q99986-1", "O94804-1", "Q9P289-1", "Q8WU08-1", "Q9NY57-1", "Q9UHD2-1", "Q86UX6-1", "Q9UKI8-1", "Q86UE8-1", "Q86Y07-1", "Q9BYP7-1", "Q9Y2K2-5", "Q96J92-1", "Q9H4A3-1", "Q9HC98-1", "Q8TDX7-1", "O14920-1", "P14618-1", "Q14296-1", "Q5SYL1-1", "E9Q3S4-1", "Q62070-1", "Q91Y86-1", "Q9Z188-1", "Q9JKK8-1", "Q05512-1", "Q66L42-1", "Q9Z1B7-1", "Q8C050-1", "Q3UHJ0-1", "Q7TT50-1", "Q61831-1", "Q99MQ3-1", "P49025-1", "Q03141-1", "Q9Z0R0-1", "Q69ZM6-1", "Q9WVS8-1", "Q7TSJ6-1", "A0A3B2WD63-1", "Q8VDU5-1", "A0A087WSA6-1", "Q9WVC6-1", "P04627-1", "Q60823-1", "O54967-1", "Q924C5-1", "Q8BRK8-1", "Q91ZB0-1", "P31750-1", "Q5EG47-1", "O88445-1", "Q5RJI5-1", "Q9Z1S0-1", "O08901-1", "P49615-1", "Q04899-1", "Q3TZA2-1", "Q8BLF2-1", "Q8R3L8-1", "Q9WUA6-1", "P24788-1", "O35495-1", "Q14AX6-1", "Q3UMM4-1", "Q64261-1", "Q8BWD8-1", "Q3UTQ8-1", "Q8CEQ0-1", "Q03147-1", "Q8K0D0-1", "O70589-1", "Q8BZ25-1", "O35491-1", "O35493-1", "Q9Z265-1", "Q69ZA1-1", "Q80YP0-1", "Q9JHU3-1", "Q9QUK0-1", "P11440-1", "Q62388-1", "Q91Z96-1", "O35280-1", "O35492-1", "P28028-3", "Q99J95-1", "P30285-1", "P97377-1", "Q9Z0H0-1", "O70126-1", "P97477-1", "P79621-1", "Q04735-1", "Q3V3A1-1", "Q69Z98-1", "Q6PAJ1-1", "Q9CXB8-1", "P22518-1", "P54265-1", "Q6XUX1-1", "Q03963-1", "Q9Z2B5-1", "O54833-1", "Q80TR8-1", "Q60737-1", "Q80YE7-1", "Q8BWQ5-1", "Q9JLM8-1", "Q6PGN3-1", "Q99KY4-1", "Q61214-1", "Q8VDF3-1", "Q922Y0-1", "O54784-1", "Q9EQY0-1", "Q8BI55-1", "Q9Z2E3-1", "Q5U4C9-1", "Q5MJS3-1", "Q9Z2R9-1", "Q9QZ05-1", "Q6PHZ2-1", "Q91YS8-1", "Q923T9-1", "P68404-1", "Q91YA2-1", "P68181-1", "Q7TPS0-1", "Q8BK63-1", "Q8BTH8-1", "Q8C4X2-1", "Q62101-1", "Q8K1Y2-1", "P16054-1", "O88904-1", "Q9ERH7-1", "Q3V016-1", "Q8R4K2-1", "Q8BVP5-1", "Q8BW96-1", "Q9QYK9-1", "P08414-1", "Q8C078-1", "P53349-1", "Q3U1V8-1", "Q80XI6-1", "Q80YE4-1", "Q3TYD6-1", "O08648-1", "Q07174-1", "Q1HKZ5-1", "Q61083-1", "Q3U214-1", "Q2NL51-1", "Q8VBY2-1", "P49138-1", "P53668-1", "Q9Z2B9-1", "P70218-1", "Q62406-1", "Q61084-1", "O88866-1", "Q61410-1", "P20444-1", "Q62074-1", "Q9WUT3-1", "P0C605-1", "P23298-1", "P63318-1", "P18653-1", "P18654-1", "Q02111-1", "Q8BLK9-1", "Q9WUL6-1", "Q9Z1M4-1", "Q8C0P0-1", "P28652-1", "Q9WV60-1", "Q8BZ03-1", "Q60700-1", "Q61161-1", "Q91VB2-1", "Q8VHJ5-1", "Q9QZR5-1", "O55222-1", "Q9JMK2-1", "O54785-1", "O35099-1", "O54992-1", "Q5S006-1", "P28867-1", "Q8BSK8-1", "Q8CIP4-1", "Q811L6-1", "Q8BPM2-1", "A2CG49-1", "Q62073-1", "Q8BYR2-1", "Q9R1L5-1", "Q9WTR2-1", "A2AQW0-1", "Q8VDG6-1", "P11798-1", "Q02956-1", "Q04859-1", "Q99JP0-1", "P97820-1", "Q61097-1", "Q3UHC2-1", "Q3UVC0-1", "Q5XJV6-1", "Q60592-1", "Q9DC28-1", "Q9JKV2-1", "Q9ESL4-1", "P05132-1", "P63085-1", "P31938-1", "Q9WVS7-1", "P00536-1", "Q3UMW7-1", "Q61532-1", "Q61846-1", "Q6P5G0-1", "Q1EG27-1", "Q8K3H5-1", "Q5SUV5-1", "Q9Z2A0-1", "Q8VD65-1", "Q8C015-1", "P47809-1", "Q3UU96-1", "P70236-1", "Q91ZR4-1", "Q7TSC3-1", "Q9R0A5-1", "Q641K5-1", "Q9R0G8-1", "Q3ULB5-1", "Q61036-1", "Q8BTW9-1", "Q8CEE6-1", "P58750-1", "P06803-1", "P53351-1", "Q60806-1", "Q8K045-1", "P07934-1", "P70268-1", "O08911-1", "Q63844-1", "Q80Y86-1", "Q9WUI1-1", "O35942-1", "Q8QZR7-1", "Q8BWW9-1", "Q8K1R7-1", "Q63932-1", "Q8BHI9-1", "O09110-1", "O54949-1", "Q8CE90-1", "Q8C0Q4-1", "O08605-1", "A2AAJ9-1", "P47811-1", "Q8CDB0-1", "P51954-1", "Q8CIN4-1", "Q80UW5-1", "Q8BZN4-1", "Q9WVS4-1", "Q9WTU6-1", "Q9Z1J2-1", "Q9JLN9-1", "O88643-1", "Q07832-1", "Q3UGM2-1", "Q9JM52-1", "Q6P9R2-1", "Q64702-1", "Q61136-1", "Q922R0-1", "P70336-1", "Q8R2S1-1", "P0C5K0-1", "P0C5K1-1", "Q9Z0G2-1", "Q8C0X8-1", "Q9QYZ4-1", "Q62407-1", "Q8C0V7-1", "O54988-1", "Q9JJ78-1", "Q3UVR3-1", "Q9D2E1-1", "Q6PCN3-1", "Q9ESG9-1", "A2KF29-1", "Q8BKX6-1", "A0AUV4-1", "Q7TSE6-1", "Q9JI10-1", "Q0KL02-1", "Q3U3Q1-1", "Q3V129-1", "Q9QY01-1", "P70335-1", "Q8CFH6-1", "Q9WUN2-1", "Q8QZX0-1", "Q8C0N0-1", "Q9ERE3-1", "Q9QZS5-1", "O88697-1", "Q80ZW0-1", "O55098-1", "Q924X7-1", "Q99KH8-1", "Q99MW1-1", "Q9Z2W1-1", "Q7TNL3-1", "Q91VJ4-1", "Q9JI11-1", "Q9DBU3-1", "Q9ERK0-1", "Q9QYZ6-1", "Q5F2E8-1", "Q6ZQ29-1", "Q8BYC6-1", "Q80UV9-1", "O70146-1", "Q8VCT9-1", "Q9QZL0-1", "Q61241-1", "Q99JT2-1", "Q8QZV4-1", "O54781-1", "O55047-1", "Q99N57-1", "Q60855-1", "Q8C0V0-1", "Q8BGW6-1", "Q8C1R0-1", "A2ASS6-1", "P35761-1", "Q8BG48-1", "C0HKC8-1", "Q9QYZ3-1", "Q922Q2-1", "O70551-1", "O70405-1", "P97313-1", "P83510-1", "P97343-1", "Q60670-1", "Q5GIG6-1", "Q6P4S6-1", "Q99PW4-1", "Q9CQS5-1", "Q9WTK7-1", "Q9D411-1", "C0HKC9-1", "Q9JJX8-1", "P58801-1", "Q9Z1W9-1", "Q923J1-1", "Q8CIR4-1", "Q925K9-1", "O54863-1", "Q8BN21-1", "Q80X41-1", "Q80XP9-1", "Q4FZD7-1", "P83741-1", "Q3UH66-1", "Q80UE6-1", "O88351-1", "Q5U452-1", "Q9ES70-1", "Q9ES74-1", "P52480-1", "Q9JIX9-1", "A2AQX6-1", "J3QK59-1", "Q3UT86-1", "A0A087WRH8-1", "A0A140LI04-1", "Q8BWE1-1", "J3KMT3-1", "A0A087WSF2-1", "Q3UTA8-1", "A0A140LJ87-1", "P13185-1", "P13186-1", "P14680-1", "P15442-1", "P15790-1", "P18961-1", "P19454-1", "P21965-1", "P22204-1", "P22216-1", "P22517-1", "P23292-1", "P23293-1", "P23561-1", "P25333-1", "P25341-1", "P25389-1", "P27466-1", "P27636-1", "P29295-1", "P32490-1", "P32600-1", "P32944-1", "P35169-1", "P36003-1", "P38615-1", "P40494-1", "P41695-1", "P43565-1", "P53894-1", "P53974-1", "Q03497-1", "Q12263-1", "P00546-1", "P05986-1", "P06243-1", "P06244-1", "P06245-1", "P06782-1", "P06784-1", "P08018-1", "P08458-1", "P11792-1", "P12688-1", "P14681-1", "P16892-1", "P17157-1", "P22211-1", "P23291-1", "P24583-1", "P32485-1", "P32562-1", "P39009-1", "P40160-1", "P41808-1", "P43568-1", "P48562-1", "P53233-1", "P53739-1", "Q00772-1", "Q03407-1", "P28708-1", "P31374-1", "P32328-1", "P32350-1", "P32361-1", "P32491-1", "P32581-1", "P32789-1", "P32801-1", "P22219-1", "P22209-1", "P24719-1", "P25390-1", "P36002-1", "P36004-1", "P38147-1", "P38622-1", "Q01919-1", "P43633-1", "P38692-1", "P38970-1", "P38990-1", "P38991-1", "P39073-1", "P39962-1", "P47116-1", "P53599-1", "P34244-1", "P36005-1", "P38070-1", "P38080-1", "P38110-1", "P38111-1", "P38623-1", "P38691-1", "P53104-1", "P53323-1", "P54199-1", "Q01389-1", "Q03656-1", "Q08217-1", "Q03306-1", "Q03533-1", "Q03785-1", "Q12003-1", "Q12100-1", "Q12196-1", "Q12236-1", "Q12469-1", "Q12505-1", "P43637-1", "P47042-1", "P50873-1", "Q03002-1", "Q06098-1", "Q08732-1", "Q12152-1", "Q12222-1", "Q12310-1", "Q54FH3-1", "Q54R98-1", "Q54RP7-1", "Q55FJ6-1", "Q55GG4-1", "Q54C38-1", "Q54DY0-1", "Q54E34-1", "Q54EM1-1", "Q54ER4-1", "Q54ET3-1", "Q54F40-1", "Q54FR9-1", "Q54G43-1", "Q54H05-1", "Q54HD2-1", "Q54IF2-1", "Q54IH8-1", "Q54IP4-1", "Q54JQ1-1", "Q54L00-1", "Q54L81-1", "Q54LH8-1", "Q54LU8-1", "Q54MH0-1", "Q54MV2-1", "Q54P26-1", "Q54PK8-1", "Q54PX0-1", "Q54QD5-1", "Q54R95-1", "Q54RB2-1", "Q54RJ4-1", "Q54RR9-1", "Q54RV3-1", "Q54RZ7-1", "Q54SC4-1", "Q54SK3-1", "Q54TA3-1", "Q54TH6-1", "Q54TN4-1", "Q54U31-1", "Q54U65-1", "Q54UA9-1", "Q54UZ1-1", "Q54V35-1", "Q54V83-1", "Q54VC0-1", "Q54VU4-1", "Q54VV7-1", "Q54WC0-1", "Q54WD7-1", "Q54WE5-1", "Q54WW7-1", "Q54XJ4-1", "Q54XX5-1", "Q54XY6-1", "Q54XZ5-1", "Q54Y06-1", "Q54Y55-1", "Q54Y90-1", "Q54YZ5-1", "Q54ZN3-1", "Q552C1-1", "Q552E9-1", "Q552Z2-1", "Q553E9-1", "Q556J6-1", "Q559A2-1", "Q559T8-1", "Q55A09-1", "Q55A55-1", "Q55BA0-1", "Q55CA6-1", "Q55CE0-1", "Q55CW2-1", "Q55CW3-1", "Q55DJ9-1", "Q55DK2-1", "Q55DU7-1", "Q55EI8-1", "Q55F45-1", "Q55FV4-1", "Q55FV5-1", "Q55GC2-1", "Q55GE6-1", "Q55GS4-1", "Q55GU0-1", "Q6XHA7-1", "Q75JN1-1", "Q76P07-1", "Q869L4-1", "Q869T7-1", "Q869X3-1", "Q86A12-1", "Q86HG9-1", "Q86HW6-1", "Q86I06-1", "Q8MYF1-1", "Q8SSV3-1", "Q9NGW9-1", "P0CD62-1", "P34100-1", "P34102-1", "P34103-1", "Q1ZXC8-1", "Q1ZXH2-1", "Q1ZXI5-1", "Q1ZXR2-1", "Q23915-1", "Q54HS0-1", "O61122-1", "O61125-1", "P28178-1", "P34099-1", "P34101-1", "P34112-1", "P34117-1", "P42525-1", "P54644-1", "P54685-1", "Q02720-1", "Q1ZXD6-1", "Q54B33-1", "Q54B48-1", "Q54BC9-1", "Q54BF0-1", "Q54C18-1", "Q54C71-1", "Q54D75-1", "Q54DC8-1", "Q54DF2-1", "Q54DK3-1", "Q54EG9-1", "Q54EY4-1", "Q54GY6-1", "Q54H45-1", "Q54H46-1", "Q54HC6-1", "Q54I36-1", "Q54IE8-1", "Q54JC7-1", "Q54JG7-1", "Q54LR6-1", "Q54M77-1", "Q54MY9-1", "Q54P47-1", "Q54PK9-1", "Q54Q69-1", "Q54QB1-1", "Q54QI2-1", "Q54QQ1-1", "Q54QV3-1", "Q54R82-1", "Q54RB7-1", "Q54S77-1", "Q54T05-1", "Q54TA1-1", "Q54TM7-1", "Q54TW2-1", "Q54UC0-1", "Q54UL8-1", "Q54VD8-1", "Q54VI1-1", "Q54W07-1", "Q54WJ0-1", "Q54WS5-1", "Q54WX4-1", "Q54XL6-1", "Q54XQ2-1", "Q54Y26-1", "Q54YF2-1", "Q550K8-1", "Q550L8-1", "Q551H4-1", "Q552C6-1", "Q556Q3-1", "Q556S2-1", "Q556Y4-1", "Q557G1-1", "Q558U1-1", "Q55BN8-1", "Q55CL6-1", "Q55CY9-1", "Q55CZ1-1", "Q55D99-1", "Q55DD4-1", "Q55DJ8-1", "Q55E58-1", "Q55EC7-1", "Q55FS2-1", "Q55FT4-1", "Q55GJ2-1", "Q55GV3-1", "Q5VJL3-1", "Q6B9X6-1", "Q6XHA5-1", "Q6XHB2-1", "Q75JK0-1", "Q76NV1-1", "Q869N2-1", "Q86AE1-1", "Q86AT8-1", "Q86C65-1", "Q86CS2-1", "Q86HN7-1", "Q86IX1-1", "Q8MVR1-1", "Q8SSS9-1", "Q8SSY6-1", "Q8T2I8-1", "Q95YH0-1", "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83098-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "A0A0B4KHX7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "M9PI41-1", "Q9VM90-1", "A1ZBL9-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P49762-1", "P54367-1", "P83099-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "Q9NIV1-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "P54360-1", "Q9VT57-1", "Q9VI13-1", "A1ZBC4-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "Q7PLI7-1", "X2JAG8-1", "O61661-1", "A4VCL2-2", "A0A0B4KHT3-1", "A0A4D6K823-1", "Q9VP22-1", "Q9VZI2-1", "Q9W1B0-1", "Q9V3I5-1", "A1ZBH7-1", "Q9W002-1", "Q9VRJ6-1", "Q8T9L5-1", "Q94533-1", "Q9VUQ9-1", "Q9VXE3-1", "Q9VGF9-1", "Q9VBU2-1", "Q9VR42-1", "Q9VW24-1", "A0A0B4KHC3-1", "Q9VL34-1", "Q9VTL5-1", "Q95TN8-1", "Q9VCV0-1", "Q8MSQ4-1", "Q9VE06-1", "Q9VJ30-1", "Q9VXN5-1", "M9PGC5-1", "Q9VN23-1", "M9NGC6-1", "O61444-1", "O62602-1", "Q9VUV4-1", "Q9VMY8-1", "Q9VD82-1", "A0A6M3Q7C8-1", "Q9W3N8-1", "Q95SH0-1", "Q9VJC2-1", "Q9VI84-1", "Q9VEN3-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-HSA-2682349", "name": "RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels", "equation": "", "summary": "Amiloride-sensitive sodium channels (SCNNs, aka ENaCs, epithelial Na+ channels, non voltage-gated sodium channels) comprises three subunits (alpha, beta and gamma) and plays an essential role in Na+ and fluid absorption in the kidney, colon and lung. The number of channels at the cell's surface (consequently its function) can be regulated. This is achieved by ubiquitination of SCNN via E3 ubiquitin-protein ligases (NED4L and WPP1) (Staub et al. 2000, Farr et al. 2000). NED4L/WPP1 is found in a signaling complex including Raf1 (RAF proto-oncogene serine/threonine-protein kinase), SGK (serum/glucocorticoid-regulated kinase) and GILZ (glucocorticoid-induced leucine zipper protein, TSC22D3) (Soundararajan et al. 2009). Ubiquitinated SCNN (Ub-SCNN) is targeted for degradation so a lesser number of channels are present at the cell surface, reducing the amount of Na+ absorption. Proline-rich sequences at the C-terminus of SCNNs include the PY motif containing a PPxY sequence. PY motifs bind WW domains of NED4L/WPP1. Protein kinases with no lysine K (WNKs) can activate SCNN activity by interacting non-enzymatically with the signaling complex, specifically SGK although the mechanism is unknown (Heise et al. 2010).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-HSA-2672342" ], "output_participant_list": [ "R-ALL-947590" ], "enzyme_list": [ "Q96PU5-1", "Q9HBY8-2", "P04049-1", "Q9BYP7-1", "Q9H0M0-1", "O00141-1", "Q9Y3S1-1", "Q96J92-1", "Q9H4A3-1", "Q96BR1-1" ], "evidence": [ { "id": "R-HSA-2682349", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2682349" } ] }, { "id": "R-HSA-6795290", "name": "TORC2 complex phosphorylates SGK1", "equation": "", "summary": "The TORC2 complex phosphorylates SGK1 at serine residue S422, located in the carboxy-terminal hydrophobic motif of SGK1. Phosphorylation at S422 contributes to SGK1 activation (Garcia-Martinez and Alessi 2008, Lu et al. 2010).", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-HSA-6795313" ], "enzyme_list": [ "P42345-1", "O00141-1" ], "evidence": [ { "id": "R-HSA-6795290", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6795290" } ] }, { "id": "R-HSA-6795460", "name": "SGK1 phosphorylates MDM2", "equation": "", "summary": "SGK1 phosphorylates MDM2 at serine residues S166 and S188, resulting in MDM2 activation (Amato et al. 2009, Lyo et al. 2010). SGK1 may play a more prominent role in MDM2 activation than AKT (Lyo et al. 2010).", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q00987-1", "O00141-1" ], "evidence": [ { "id": "R-HSA-6795460", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6795460" } ] }, { "id": "R-HSA-6795473", "name": "PDPK1 phosphorylates SGK1", "equation": "", "summary": "PDPK1 (PDK1) activates SGK1 by phosphorylating threonine residue T256, located in the activation loop of SGK1. Phosphorylation of SGK1 at S422 facilitates subsequent phosphorylation at T256 (Kobayashi and Cohen 1999).", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-HSA-6795449" ], "enzyme_list": [ "O15530-1", "O00141-1" ], "evidence": [ { "id": "R-HSA-6795473", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-6795473" } ] }, { "id": "R-HSA-9022764", "name": "SGK1 gene expression is inhibited by MECP2", "equation": "", "summary": "Based on studies in mice, MECP2 directly inhibits transcription of the SGK1 gene encoding serum/glucocorticoid-regulated kinase 1. Sgk1 level is increased in Mecp2 null mice (Nuber et al. 2005).", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [ "R-HSA-9022779" ], "output_participant_list": [ "R-HSA-2682356" ], "enzyme_list": [ "O00141-1" ], "evidence": [ { "id": "R-HSA-9022764", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9022764" } ] }, { "id": "R-HSA-9612501", "name": "SGK phosphorylates CREB1", "equation": "", "summary": "Serum/glucocorticoid-induced kinase (SGK) phosphorylates CREB1 at S119 downstream of mutiple cellular stimuli (Lee et al, 1995; David et al, 2005). SGK activity contributes to EGR1 gene expression by promoting the phosphorylation of CREB1 and SRF transcription factor, both of which have binding sites in the EGR1 promoter (Tyan et al, 2008; Sakomoto et al, 1991; Schwachtgen et al, 2000).", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O00141-1" ], "evidence": [ { "id": "R-HSA-9612501", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9612501" } ] }, { "id": "R-HSA-9612509", "name": "SGK phosphorylates SRF", "equation": "", "summary": "Serum/glucticocorticoid kinase (SGK) phosphorylates SRF at serine residue 103 in response to multiple upstream stimuli (Tyan et al, 2008). Phosphorylation of SRF and CREB1 by SGK contributes to the SGK-dependent expression of EGR1, an immediate early gene with roles in neuronal development, (David et al, 2005; Tyan et al, 2008; reviewed in Pagel and Deindl, 2011).", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-HSA-9612518" ], "enzyme_list": [ "O00141-1" ], "evidence": [ { "id": "R-HSA-9612509", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9612509" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-947590", "participant_name": "Pi [plasma membrane]", "crossref": [ { "id": "C00009", "database": "COMPOUND", "url": "" }, { "id": "43474", "database": "ChEBI", "url": "" }, { "id": "C00009", "database": "COMPOUND", "url": "" }, { "id": "43474", "database": "ChEBI", "url": "" }, { "id": "C00009", "database": "COMPOUND", "url": "" }, { "id": "43474", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-HSA-2672342", "participant_name": "SCNN channels [plasma membrane]", "crossref": [ { "id": "CPX-312", "database": "ComplexPortal", "url": "" } ] }, { "participant_id": "R-HSA-2682356", "participant_name": "SGK1 [cytosol]", "crossref": [ { "id": "SGK1_HUMAN", "database": "ZINC - Substances", "url": "" }, { "id": "XP_011534373.1", "database": "RefSeq", "url": "" }, { "id": "ENSP00000237305", "database": "Ensembl", "url": "" }, { "id": "O00141", "database": "UniProt", "url": "" }, { "id": "3HDM", "database": "PDB", "url": "" }, { "id": "O00141", "database": "Pharos - Targets", "url": "" }, { "id": "O00141", "database": "PRO", "url": "" }, { "id": "ENSP00000356832", "database": "Ensembl", "url": "" }, { "id": "NP_001278924.1", "database": "RefSeq", "url": "" }, { "id": "7PUE", "database": "PDB", "url": "" }, { "id": "ENSG00000118515", "database": "Ensembl", "url": "" }, { "id": "3HDN", "database": "PDB", "url": "" }, { "id": "ENSP00000434450", "database": "Ensembl", "url": "" }, { "id": "ENSP00000396242", "database": "Ensembl", "url": "" }, { "id": "NP_001137149.1", "database": "RefSeq", "url": "" }, { "id": "O00141", "database": "GeneCards", "url": "" }, { "id": "O00141", "database": "ZINC target", "url": "" }, { "id": "ENSG00000118515-SGK1", "database": "HPA", "url": "" }, { "id": "ENST00000528577", "database": "Ensembl", "url": "" }, { "id": "NP_005618.2", "database": "RefSeq", "url": "" }, { "id": "ENST00000367858", "database": "Ensembl", "url": "" }, { "id": "1534", "database": "Guide to Pharmacology - Targets", "url": "" }, { "id": "HMDBP01258", "database": "HMDB Protein", "url": "" }, { "id": "NP_001137148.1", "database": "RefSeq", "url": "" }, { "id": "ENSP00000356831", "database": "Ensembl", "url": "" }, { "id": "ENST00000237305", "database": "Ensembl", "url": "" }, { "id": "2R5T", "database": "PDB", "url": "" }, { "id": "ENST00000367857", "database": "Ensembl", "url": "" }, { "id": "NP_001137150.1", "database": "RefSeq", "url": "" }, { "id": "ENSG00000118515", "database": "OpenTargets", "url": "" }, { "id": "ENST00000413996", "database": "Ensembl", "url": "" }, { "id": "SGK1_HUMAN", "database": "ZINC - Predictions - Purchasable", "url": "" } ] }, { "participant_id": "R-HSA-6795313", "participant_name": "p-S422-SGK1 [cytosol]", "crossref": [ { "id": "XP_011534373.1", "database": "RefSeq", "url": "" }, { "id": "ENSP00000237305", "database": "Ensembl", "url": "" }, { "id": "O00141", "database": "UniProt", "url": "" }, { "id": "SGK1_HUMAN", "database": "ZINC - Substances", "url": "" }, { "id": "O00141", "database": "PRO", "url": "" }, { "id": "ENSP00000356832", "database": "Ensembl", "url": "" }, { "id": "O00141", "database": "Pharos - Targets", "url": "" }, { "id": "3HDM", "database": "PDB", "url": "" }, { "id": "NP_001278924.1", "database": "RefSeq", "url": "" }, { "id": "7PUE", "database": "PDB", "url": "" }, { "id": "ENSG00000118515", "database": "Ensembl", "url": "" }, { "id": "3HDN", "database": "PDB", "url": "" }, { "id": "ENSP00000434450", "database": "Ensembl", "url": "" }, { "id": "ENSP00000396242", "database": "Ensembl", "url": "" }, { "id": "NP_001137149.1", "database": "RefSeq", "url": "" }, { "id": "O00141", "database": "GeneCards", "url": "" }, { "id": "O00141", "database": "ZINC target", "url": "" }, { "id": "ENSG00000118515", "database": "OpenTargets", "url": "" }, { "id": "ENST00000413996", "database": "Ensembl", "url": "" }, { "id": "SGK1_HUMAN", "database": "ZINC - Predictions - Purchasable", "url": "" }, { "id": "ENST00000367857", "database": "Ensembl", "url": "" }, { "id": "2R5T", "database": "PDB", "url": "" }, { "id": "NP_001137150.1", "database": "RefSeq", "url": "" }, { "id": "ENST00000237305", "database": "Ensembl", "url": "" }, { "id": "ENSP00000356831", "database": "Ensembl", "url": "" }, { "id": "ENSG00000118515-SGK1", "database": "HPA", "url": "" }, { "id": "NP_005618.2", "database": "RefSeq", "url": "" }, { "id": "ENST00000528577", "database": "Ensembl", "url": "" }, { "id": "HMDBP01258", "database": "HMDB Protein", "url": "" }, { "id": "NP_001137148.1", "database": "RefSeq", "url": "" }, { "id": "ENST00000367858", "database": "Ensembl", "url": "" }, { "id": "1534", "database": "Guide to Pharmacology - Targets", "url": "" } ] }, { "participant_id": "R-HSA-6795449", "participant_name": "p-T256,S422-SGK1 [cytosol]", "crossref": [ { "id": "SGK1_HUMAN", "database": "ZINC - Substances", "url": "" }, { "id": "O00141", "database": "UniProt", "url": "" }, { "id": "XP_011534373.1", "database": "RefSeq", "url": "" }, { "id": "ENSP00000237305", "database": "Ensembl", "url": "" }, { "id": "O00141", "database": "PRO", "url": "" }, { "id": "ENSP00000356832", "database": "Ensembl", "url": "" }, { "id": "O00141", "database": "Pharos - Targets", "url": "" }, { "id": "3HDM", "database": "PDB", "url": "" }, { "id": "NP_001278924.1", "database": "RefSeq", "url": "" }, { "id": "7PUE", "database": "PDB", "url": "" }, { "id": "ENSG00000118515", "database": "Ensembl", "url": "" }, { "id": "3HDN", "database": "PDB", "url": "" }, { "id": "ENSP00000434450", "database": "Ensembl", "url": "" }, { "id": "ENSP00000396242", "database": "Ensembl", "url": "" }, { "id": "NP_001137149.1", "database": "RefSeq", "url": "" }, { "id": "O00141", "database": "GeneCards", "url": "" }, { "id": "O00141", "database": "ZINC target", "url": "" }, { "id": "ENSG00000118515", "database": "OpenTargets", "url": "" }, { "id": "ENST00000413996", "database": "Ensembl", "url": "" }, { "id": "SGK1_HUMAN", "database": "ZINC - Predictions - Purchasable", "url": "" }, { "id": "ENST00000367857", "database": "Ensembl", "url": "" }, { "id": "2R5T", "database": "PDB", "url": "" }, { "id": "NP_001137150.1", "database": "RefSeq", "url": "" }, { "id": "ENST00000237305", "database": "Ensembl", "url": "" }, { "id": "ENSP00000356831", "database": "Ensembl", "url": "" }, { "id": "ENSG00000118515-SGK1", "database": "HPA", "url": "" }, { "id": "NP_005618.2", "database": "RefSeq", "url": "" }, { "id": "ENST00000528577", "database": "Ensembl", "url": "" }, { "id": "HMDBP01258", "database": "HMDB Protein", "url": "" }, { "id": "1534", "database": "Guide to Pharmacology - Targets", "url": "" }, { "id": "ENST00000367858", "database": "Ensembl", "url": "" }, { "id": "NP_001137148.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-HSA-9022779", "participant_name": "SGK1 gene [nucleoplasm]", "crossref": [ { "id": "ENSG00000118515", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-HSA-9612518", "participant_name": "p-S103 SRF [nucleoplasm]", "crossref": [ { "id": "P11831", "database": "UniProt", "url": "" }, { "id": "25606", "database": "Orphanet", "url": "" }, { "id": "ENSG00000112658", "database": "OpenTargets", "url": "" }, { "id": "ENSG00000112658-SRF", "database": "HPA", "url": "" }, { "id": "NP_003122.1", "database": "RefSeq", "url": "" }, { "id": "1SRS", "database": "PDB", "url": "" }, { "id": "ENSG00000112658", "database": "Ensembl", "url": "" }, { "id": "P11831", "database": "PRO", "url": "" }, { "id": "NP_001278930.1", "database": "RefSeq", "url": "" }, { "id": "1K6O", "database": "PDB", "url": "" }, { "id": "ENST00000265354", "database": "Ensembl", "url": "" }, { "id": "P11831", "database": "GeneCards", "url": "" }, { "id": "1HBX", "database": "PDB", "url": "" }, { "id": "P11831", "database": "Pharos - Targets", "url": "" }, { "id": "ENSP00000265354", "database": "Ensembl", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A087WRH8", "gene_name": "Gm5157", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A087WRH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WRH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A087WRH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WRH8" } ] } ] }, { "uniprot_ac": "A0A087WSA6", "gene_name": "Gm7358", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A087WSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A087WSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSA6" } ] } ] }, { "uniprot_ac": "A0A087WSF2", "gene_name": "Smok3c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A087WSF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A087WSF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A087WSF2" } ] } ] }, { "uniprot_ac": "A0A0B4J2F2", "gene_name": "SIK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4J2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4J2F2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4J2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4J2F2" } ] } ] }, { "uniprot_ac": "A0A0B4KHC3", "gene_name": "PKD", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3" } ] } ] }, { "uniprot_ac": "A0A0B4KHT3", "gene_name": "Lrrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHT3" } ] } ] }, { "uniprot_ac": "A0A0B4KHX7", "gene_name": "Gcn2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B4KHX7" } ] } ] }, { "uniprot_ac": "A0A0G2JUP3", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3" } ] } ] }, { "uniprot_ac": "A0A0G2JVL3", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JVL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JVL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3" } ] } ] }, { "uniprot_ac": "A0A0G2JWX7", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JWX7" } ] } ] }, { "uniprot_ac": "A0A0G2JXR8", "gene_name": "LOC100911229", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JXR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JXR8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JXR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JXR8" } ] } ] }, { "uniprot_ac": "A0A0G2JZW9", "gene_name": "ENSRNOG00000068522", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2JZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2JZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9" } ] } ] }, { "uniprot_ac": "A0A0G2K2T8", "gene_name": "RGD1565143", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K2T8" } ] } ] }, { "uniprot_ac": "A0A0G2K344", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A0G2K344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K344" } ] } ] }, { "uniprot_ac": "A0A0G2K490", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K490" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K490" } ] } ] }, { "uniprot_ac": "A0A0G2K578", "gene_name": "AABR07068650.1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K578" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K578" } ] } ] }, { "uniprot_ac": "A0A0G2K5C7", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5C7" } ] } ] }, { "uniprot_ac": "A0A0G2K5L3", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K5L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K5L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K5L3" } ] } ] }, { "uniprot_ac": "A0A0G2K6V9", "gene_name": "RGD1564409", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2K6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2K6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9" } ] } ] }, { "uniprot_ac": "A0A0G2KAH6", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2KAH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2KAH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH6" } ] } ] }, { "uniprot_ac": "A0A0G2KB60", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2KB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2KB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KB60" } ] } ] }, { "uniprot_ac": "A0A0G2QC55", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A0G2QC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0G2QC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2QC55" } ] } ] }, { "uniprot_ac": "A0A140LI04", "gene_name": "Gm5890", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A140LI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LI04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A140LI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LI04" } ] } ] }, { "uniprot_ac": "A0A140LJ87", "gene_name": "Gm4565", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A140LJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LJ87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A140LJ87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LJ87" } ] } ] }, { "uniprot_ac": "A0A3B2WD63", "gene_name": "Gm7356", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A3B2WD63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3B2WD63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3B2WD63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3B2WD63" } ] } ] }, { "uniprot_ac": "A0A4D6K823", "gene_name": "nmo", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K823" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A4D6K823" } ] } ] }, { "uniprot_ac": "A0A6M3Q7C8", "gene_name": "SRPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A6M3Q7C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A6M3Q7C8" } ] } ] }, { "uniprot_ac": "A0A8I5Y7S3", "gene_name": "LOC120097771", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5Y7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7S3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5Y7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y7S3" } ] } ] }, { "uniprot_ac": "A0A8I5Y8C3", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5Y8C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5Y8C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8C3" } ] } ] }, { "uniprot_ac": "A0A8I5ZKJ9", "gene_name": "ENSRNOG00000070867", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZKJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZKJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKJ9" } ] } ] }, { "uniprot_ac": "A0A8I5ZLV4", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZLV4" } ] } ] }, { "uniprot_ac": "A0A8I5ZMP0", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMP0" } ] } ] }, { "uniprot_ac": "A0A8I5ZN46", "gene_name": "LOC108353138", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN46" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZN46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZN46" } ] } ] }, { "uniprot_ac": "A0A8I5ZNK2", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZNK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZNK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZNK2" } ] } ] }, { "uniprot_ac": "A0A8I5ZP97", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8I5ZP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97" } ] } ] }, { "uniprot_ac": "A0A8I5ZR62", "gene_name": "RGD1565071", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZR62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZR62" } ] } ] }, { "uniprot_ac": "A0A8I5ZS27", "gene_name": "LOC102555239", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZS27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZS27" } ] } ] }, { "uniprot_ac": "A0A8I5ZSS7", "gene_name": "LOC102546375", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSS7" } ] } ] }, { "uniprot_ac": "A0A8I5ZT61", "gene_name": "LOC300308", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZT61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZT61" } ] } ] }, { "uniprot_ac": "A0A8I5ZUS1", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUS1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8I5ZUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUS1" } ] } ] }, { "uniprot_ac": "A0A8I5ZUX6", "gene_name": "RGD1566007", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZUX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZUX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZUX6" } ] } ] }, { "uniprot_ac": "A0A8I5ZV60", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZV60" } ] } ] }, { "uniprot_ac": "A0A8I5ZYM4", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8I5ZYM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZYM4" } ] } ] }, { "uniprot_ac": "A0A8I5ZZZ6", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I5ZZZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I5ZZZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ6" } ] } ] }, { "uniprot_ac": "A0A8I6A0F8", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A0F8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A0F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A0F8" } ] } ] }, { "uniprot_ac": "A0A8I6A165", "gene_name": "LOC120093114", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A165" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A165" } ] } ] }, { "uniprot_ac": "A0A8I6A1U5", "gene_name": "LOC120093094", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A1U5" } ] } ] }, { "uniprot_ac": "A0A8I6A574", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A574" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A574", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A574" } ] } ] }, { "uniprot_ac": "A0A8I6A7D1", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A7D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A7D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7D1" } ] } ] }, { "uniprot_ac": "A0A8I6A7V5", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7V5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8I6A7V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A7V5" } ] } ] }, { "uniprot_ac": "A0A8I6A8U4", "gene_name": "ENSRNOG00000066428", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A8U4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A8U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A8U4" } ] } ] }, { "uniprot_ac": "A0A8I6A9X0", "gene_name": "LOC120100104", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6A9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A9X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6A9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6A9X0" } ] } ] }, { "uniprot_ac": "A0A8I6AAX5", "gene_name": "LOC120099682", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AAX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AAX5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AAX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AAX5" } ] } ] }, { "uniprot_ac": "A0A8I6ACE8", "gene_name": "LOC100910657", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ACE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACE8" } ] } ] }, { "uniprot_ac": "A0A8I6ACR1", "gene_name": "ENSRNOG00000067256", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ACR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACR1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ACR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ACR1" } ] } ] }, { "uniprot_ac": "A0A8I6AD01", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AD01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AD01" } ] } ] }, { "uniprot_ac": "A0A8I6AEL0", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AEL0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8I6AEL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AEL0" } ] } ] }, { "uniprot_ac": "A0A8I6AHQ6", "gene_name": "Nek2l1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AHQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AHQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AHQ6" } ] } ] }, { "uniprot_ac": "A0A8I6AJD2", "gene_name": "LOC103690174", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AJD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AJD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJD2" } ] } ] }, { "uniprot_ac": "A0A8I6AJX5", "gene_name": "RGD1561440", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJX5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8I6AJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AJX5" } ] } ] }, { "uniprot_ac": "A0A8I6ANX6", "gene_name": "Dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ANX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ANX6" } ] } ] }, { "uniprot_ac": "A0A8I6AQN6", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQN6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQN6" } ] } ] }, { "uniprot_ac": "A0A8I6ATH0", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ATH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6ATH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATH0" } ] } ] }, { "uniprot_ac": "A0A8I6ATM1", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6ATM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATM1" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8I6ATM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ATM1" } ] } ] }, { "uniprot_ac": "A0A8I6AUJ4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AUJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6AUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AUJ4" } ] } ] }, { "uniprot_ac": "A0A8I6AWX7", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6AWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8I6AWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7" } ] } ] }, { "uniprot_ac": "A0A8I6G1H3", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G1H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G1H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3" } ] } ] }, { "uniprot_ac": "A0A8I6G5Z0", "gene_name": "AABR07072539.5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G5Z0" } ] } ] }, { "uniprot_ac": "A0A8I6G980", "gene_name": "LOC100911984", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6G980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G980" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6G980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6G980" } ] } ] }, { "uniprot_ac": "A0A8I6GBQ0", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GBQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GBQ0" } ] } ] }, { "uniprot_ac": "A0A8I6GDY5", "gene_name": "RGD1564651", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GDY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GDY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GDY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GDY5" } ] } ] }, { "uniprot_ac": "A0A8I6GI15", "gene_name": "RGD1560718", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GI15" } ] } ] }, { "uniprot_ac": "A0A8I6GJV1", "gene_name": "ENSRNOG00000069390", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GJV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GJV1" } ] } ] }, { "uniprot_ac": "A0A8I6GK16", "gene_name": "LOC102549716", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK16" } ] } ] }, { "uniprot_ac": "A0A8I6GK52", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GK52" } ] } ] }, { "uniprot_ac": "A0A8I6GKS8", "gene_name": "LOC120093063", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GKS8" } ] } ] }, { "uniprot_ac": "A0A8I6GM03", "gene_name": "LOC685793", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8I6GM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GM03" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8I6GM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GM03" } ] } ] }, { "uniprot_ac": "A0A8J8XEH6", "gene_name": "ENSRNOG00000067334", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0A8J8XEH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8J8XEH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8J8XEH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8J8XEH6" } ] } ] }, { "uniprot_ac": "A0AUV4", "gene_name": "Gm7168", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A0AUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0AUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0AUV4" } ] } ] }, { "uniprot_ac": "A1A5Q6", "gene_name": "Smok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1A5Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1A5Q6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1A5Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1A5Q6" } ] } ] }, { "uniprot_ac": "A1Z7T0", "gene_name": "Pkn", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z7T0" } ] } ] }, { "uniprot_ac": "A1Z9X0", "gene_name": "aPKC", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z9X0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1Z9X0" } ] } ] }, { "uniprot_ac": "A1ZBC4", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBC4" } ] } ] }, { "uniprot_ac": "A1ZBH7", "gene_name": "hppy", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBH7" } ] } ] }, { "uniprot_ac": "A1ZBL9", "gene_name": "par-1", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A1ZBL9" } ] } ] }, { "uniprot_ac": "A2AAJ9", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AAJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AAJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2AAJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AAJ9" } ] } ] }, { "uniprot_ac": "A2AQW0", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQW0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2AQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQW0" } ] } ] }, { "uniprot_ac": "A2AQX6", "gene_name": "Gm14151", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2AQX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2AQX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AQX6" } ] } ] }, { "uniprot_ac": "A2ASS6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2ASS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ASS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2ASS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ASS6" } ] } ] }, { "uniprot_ac": "A2CG49", "gene_name": "Kalrn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2CG49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2CG49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2CG49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2CG49" } ] } ] }, { "uniprot_ac": "A2KF29", "gene_name": "Smoktcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A2KF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2KF29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2KF29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2KF29" } ] } ] }, { "uniprot_ac": "A4L9P5", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A4L9P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4L9P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4L9P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4L9P5" } ] } ] }, { "uniprot_ac": "A4VCL2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4VCL2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A4VCL2" } ] } ] }, { "uniprot_ac": "A6HK01", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A6HK01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HK01" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A6HK01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6HK01" } ] } ] }, { "uniprot_ac": "A6KB61", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "A6KB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KB61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A6KB61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KB61" } ] } ] }, { "uniprot_ac": "B0G126", "gene_name": "pip5k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "B0G126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0G126" } ] } ] }, { "uniprot_ac": "B0LT89", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B0LT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0LT89" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0LT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B0LT89" } ] } ] }, { "uniprot_ac": "B1WBT4", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B1WBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B1WBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBT4" } ] } ] }, { "uniprot_ac": "B1WBU5", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B1WBU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B1WBU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1WBU5" } ] } ] }, { "uniprot_ac": "B2DD29", "gene_name": "Brsk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B2DD29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2DD29" } ] } ] }, { "uniprot_ac": "B2GUY1", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B2GUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUY1" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "B2GUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUY1" } ] } ] }, { "uniprot_ac": "B5DFG1", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "B5DFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B5DFG1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B5DFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B5DFG1" } ] } ] }, { "uniprot_ac": "C0HKC8", "gene_name": "Smok3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "C0HKC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C0HKC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC8" } ] } ] }, { "uniprot_ac": "C0HKC9", "gene_name": "Smok3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "C0HKC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C0HKC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/C0HKC9" } ] } ] }, { "uniprot_ac": "D3Z822", "gene_name": "Atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z822" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z822", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z822" } ] } ] }, { "uniprot_ac": "D3Z837", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z837" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z837", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z837" } ] } ] }, { "uniprot_ac": "D3Z8E0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8E0" } ] } ] }, { "uniprot_ac": "D3Z8I4", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3Z8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8I4" } ] } ] }, { "uniprot_ac": "D3ZBE5", "gene_name": "Nek7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZBE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBE5" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "D3ZBE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBE5" } ] } ] }, { "uniprot_ac": "D3ZBS8", "gene_name": "LOC690235", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZBS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZBS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBS8" } ] } ] }, { "uniprot_ac": "D3ZCD7", "gene_name": "Tp53rkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZCD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZCD7" } ] } ] }, { "uniprot_ac": "D3ZD18", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZD18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD18" } ] } ] }, { "uniprot_ac": "D3ZDM6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZDM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDM6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "D3ZDM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZDM6" } ] } ] }, { "uniprot_ac": "D3ZEK4", "gene_name": "Tssk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEK4" } ] } ] }, { "uniprot_ac": "D3ZFL3", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZFL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFL3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZFL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFL3" } ] } ] }, { "uniprot_ac": "D3ZG83", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG83" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZG83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG83" } ] } ] }, { "uniprot_ac": "D3ZGQ5", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZGQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZGQ5" } ] } ] }, { "uniprot_ac": "D3ZHL6", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZHL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHL6" } ] } ] }, { "uniprot_ac": "D3ZHP7", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHP7" } ] } ] }, { "uniprot_ac": "D3ZJ84", "gene_name": "Tssk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJ84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZJ84" } ] } ] }, { "uniprot_ac": "D3ZL21", "gene_name": "Tp53rka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZL21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZL21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZL21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZL21" } ] } ] }, { "uniprot_ac": "D3ZMG0", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZMG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZMG0" } ] } ] }, { "uniprot_ac": "D3ZML2", "gene_name": "Brsk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "D3ZML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZML2" } ] } ] }, { "uniprot_ac": "D3ZQN8", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZQN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZQN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQN8" } ] } ] }, { "uniprot_ac": "D3ZRJ7", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZRJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZRJ7" } ] } ] }, { "uniprot_ac": "D3ZSB7", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSB7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSB7" } ] } ] }, { "uniprot_ac": "D3ZSY9", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZSY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSY9" } ] } ] }, { "uniprot_ac": "D3ZSZ3", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSZ3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "D3ZSZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSZ3" } ] } ] }, { "uniprot_ac": "D3ZTD1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZTD1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D3ZTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZTD1" } ] } ] }, { "uniprot_ac": "D3ZXB1", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZXB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZXB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZXB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZXB1" } ] } ] }, { "uniprot_ac": "D3ZY07", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZY07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZY07" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "D3ZY07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZY07" } ] } ] }, { "uniprot_ac": "D3ZZK7", "gene_name": "Myo3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D3ZZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D3ZZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZZK7" } ] } ] }, { "uniprot_ac": "D4A229", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A229" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "D4A229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A229" } ] } ] }, { "uniprot_ac": "D4A280", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A280" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A280" } ] } ] }, { "uniprot_ac": "D4A355", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A355" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A355" } ] } ] }, { "uniprot_ac": "D4A3D9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3D9" } ] } ] }, { "uniprot_ac": "D4A3H8", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3H8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A3H8" } ] } ] }, { "uniprot_ac": "D4A454", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A454" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "D4A454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A454" } ] } ] }, { "uniprot_ac": "D4A6T6", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A6T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A6T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T6" } ] } ] }, { "uniprot_ac": "D4A6T9", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A6T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A6T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6T9" } ] } ] }, { "uniprot_ac": "D4A7V9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A7V9" } ] } ] }, { "uniprot_ac": "D4A949", "gene_name": "Smokl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A949" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A949" } ] } ] }, { "uniprot_ac": "D4A9H8", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4A9H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A9H8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4A9H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A9H8" } ] } ] }, { "uniprot_ac": "D4ACL8", "gene_name": "Atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4ACL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACL8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4ACL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACL8" } ] } ] }, { "uniprot_ac": "D4AD76", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AD76" } ] } ] }, { "uniprot_ac": "D4AE24", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AE24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AE24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE24" } ] } ] }, { "uniprot_ac": "D4AE59", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "D4AE59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "D4AE59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AE59" } ] } ] }, { "uniprot_ac": "E9PSK5", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSK5" } ] } ] }, { "uniprot_ac": "E9PSL7", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSL7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSL7" } ] } ] }, { "uniprot_ac": "E9PSM2", "gene_name": "LOC301165", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PSM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PSM2" } ] } ] }, { "uniprot_ac": "E9PTG8", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9PTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9PTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTG8" } ] } ] }, { "uniprot_ac": "E9Q3S4", "gene_name": "Map3k19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "E9Q3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E9Q3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9Q3S4" } ] } ] }, { "uniprot_ac": "F1LNJ1", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LNJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LNJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ1" } ] } ] }, { "uniprot_ac": "F1LNN8", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNN8" } ] } ] }, { "uniprot_ac": "F1LP90", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LP90" } ] } ] }, { "uniprot_ac": "F1LRA7", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LRA7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1LRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LRA7" } ] } ] }, { "uniprot_ac": "F1LTP9", "gene_name": "LOC120093110", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTP9" } ] } ] }, { "uniprot_ac": "F1LUY7", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LUY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUY7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1LUY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUY7" } ] } ] }, { "uniprot_ac": "F1LWF2", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWF2" } ] } ] }, { "uniprot_ac": "F1LWJ6", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWJ6" } ] } ] }, { "uniprot_ac": "F1LXF1", "gene_name": "Bcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LXF1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1LXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LXF1" } ] } ] }, { "uniprot_ac": "F1LYY7", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1LYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LYY7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1LYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LYY7" } ] } ] }, { "uniprot_ac": "F1M0Z1", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M0Z1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M0Z1" } ] } ] }, { "uniprot_ac": "F1M419", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M419" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M419" } ] } ] }, { "uniprot_ac": "F1M7G0", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7G0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M7G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7G0" } ] } ] }, { "uniprot_ac": "F1M7N7", "gene_name": "Rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7N7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1M7N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7N7" } ] } ] }, { "uniprot_ac": "F1M7Y5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7Y5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1M7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M7Y5" } ] } ] }, { "uniprot_ac": "F1M9D0", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F1M9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9D0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1M9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9D0" } ] } ] }, { "uniprot_ac": "F7FMK8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "F7FMK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7FMK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F7FMK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7FMK8" } ] } ] }, { "uniprot_ac": "G3V783", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3V783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V783" } ] } ] }, { "uniprot_ac": "J3KMT3", "gene_name": "Gm6882", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "J3KMT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3KMT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "J3KMT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3KMT3" } ] } ] }, { "uniprot_ac": "J3QK59", "gene_name": "Gm6176", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "J3QK59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3QK59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "J3QK59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/J3QK59" } ] } ] }, { "uniprot_ac": "M0R777", "gene_name": "LOC102551633", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0R777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R777" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0R777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R777" } ] } ] }, { "uniprot_ac": "M0R7E7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0R7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R7E7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "M0R7E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R7E7" } ] } ] }, { "uniprot_ac": "M0RBT0", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RBT0" } ] } ] }, { "uniprot_ac": "M0RD40", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD40" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD40" } ] } ] }, { "uniprot_ac": "M0RD88", "gene_name": "Smok2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RD88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RD88" } ] } ] }, { "uniprot_ac": "M0RDM0", "gene_name": "LOC103689976", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M0RDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RDM0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M0RDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RDM0" } ] } ] }, { "uniprot_ac": "M9NGC6", "gene_name": "Srpk79D", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9NGC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9NGC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9NGC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9NGC6" } ] } ] }, { "uniprot_ac": "M9PGC5", "gene_name": "Wnk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PGC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PGC5" } ] } ] }, { "uniprot_ac": "M9PI41", "gene_name": "sti", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M9PI41" } ] } ] }, { "uniprot_ac": "O00141", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00141" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00141" } ] } ] }, { "uniprot_ac": "O00311", "gene_name": "CDC7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00311", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00311" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00311", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00311" } ] } ] }, { "uniprot_ac": "O00444", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00444" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O00444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00444" } ] } ] }, { "uniprot_ac": "O00506", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O00506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00506" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O00506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00506" } ] } ] }, { "uniprot_ac": "O08605", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08605" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08605" } ] } ] }, { "uniprot_ac": "O08648", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08648" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O08648", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08648" } ] } ] }, { "uniprot_ac": "O08678", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "O08678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08678" } ] } ] }, { "uniprot_ac": "O08679", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "O08679", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08679" } ] } ] }, { "uniprot_ac": "O08815", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08815" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08815" } ] } ] }, { "uniprot_ac": "O08874", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08874" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "O08874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08874" } ] } ] }, { "uniprot_ac": "O08875", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08875" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08875" } ] } ] }, { "uniprot_ac": "O08901", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08901" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O08901", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08901" } ] } ] }, { "uniprot_ac": "O08911", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O08911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08911" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O08911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O08911" } ] } ] }, { "uniprot_ac": "O09110", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O09110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09110" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O09110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09110" } ] } ] }, { "uniprot_ac": "O14578", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14578" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14578" } ] } ] }, { "uniprot_ac": "O14730", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14730" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14730" } ] } ] }, { "uniprot_ac": "O14733", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14733" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O14733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14733" } ] } ] }, { "uniprot_ac": "O14757", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14757" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14757" } ] } ] }, { "uniprot_ac": "O14874", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14874" } ] } ] }, { "uniprot_ac": "O14920", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14920" } ] } ] }, { "uniprot_ac": "O14936", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14936" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14936" } ] } ] }, { "uniprot_ac": "O14965", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14965" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14965" } ] } ] }, { "uniprot_ac": "O14976", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O14976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14976" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O14976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14976" } ] } ] }, { "uniprot_ac": "O15021", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15021" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15021" } ] } ] }, { "uniprot_ac": "O15075", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15075", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15075" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15075", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15075" } ] } ] }, { "uniprot_ac": "O15264", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15264" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O15264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15264" } ] } ] }, { "uniprot_ac": "O15530", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O15530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15530" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O15530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O15530" } ] } ] }, { "uniprot_ac": "O35099", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35099" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O35099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35099" } ] } ] }, { "uniprot_ac": "O35280", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35280" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O35280", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35280" } ] } ] }, { "uniprot_ac": "O35491", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35491" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35491" } ] } ] }, { "uniprot_ac": "O35492", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35492" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35492", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35492" } ] } ] }, { "uniprot_ac": "O35493", "gene_name": "Clk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35493" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O35493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35493" } ] } ] }, { "uniprot_ac": "O35495", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35495" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35495" } ] } ] }, { "uniprot_ac": "O35831", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35831" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35831" } ] } ] }, { "uniprot_ac": "O35832", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35832" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35832" } ] } ] }, { "uniprot_ac": "O35942", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O35942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35942" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O35942", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35942" } ] } ] }, { "uniprot_ac": "O43283", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43283" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O43283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43283" } ] } ] }, { "uniprot_ac": "O43293", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43293" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43293" } ] } ] }, { "uniprot_ac": "O43318", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43318" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O43318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43318" } ] } ] }, { "uniprot_ac": "O43353", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43353" } ] } ] }, { "uniprot_ac": "O43683", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43683" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43683" } ] } ] }, { "uniprot_ac": "O43781", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43781" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O43781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43781" } ] } ] }, { "uniprot_ac": "O43930", "gene_name": "PRKY", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O43930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43930" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O43930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O43930" } ] } ] }, { "uniprot_ac": "O54748", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54748" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54748" } ] } ] }, { "uniprot_ac": "O54781", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54781" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54781" } ] } ] }, { "uniprot_ac": "O54784", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54784" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54784" } ] } ] }, { "uniprot_ac": "O54785", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54785" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54785" } ] } ] }, { "uniprot_ac": "O54833", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54833" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54833" } ] } ] }, { "uniprot_ac": "O54863", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54863" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54863" } ] } ] }, { "uniprot_ac": "O54874", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54874" } ] } ] }, { "uniprot_ac": "O54949", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54949" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O54949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54949" } ] } ] }, { "uniprot_ac": "O54967", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54967" } ] } ] }, { "uniprot_ac": "O54988", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54988", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54988" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54988", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54988" } ] } ] }, { "uniprot_ac": "O54992", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O54992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54992" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O54992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54992" } ] } ] }, { "uniprot_ac": "O55028", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55028" } ] } ] }, { "uniprot_ac": "O55047", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55047" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55047" } ] } ] }, { "uniprot_ac": "O55098", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] } ] }, { "uniprot_ac": "O55099", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55099" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55099" } ] } ] }, { "uniprot_ac": "O55173", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55173" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55173" } ] } ] }, { "uniprot_ac": "O55222", "gene_name": "Ilk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55222" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55222" } ] } ] }, { "uniprot_ac": "O60229", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60229" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60229", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60229" } ] } ] }, { "uniprot_ac": "O60285", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60285" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60285" } ] } ] }, { "uniprot_ac": "O60307", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60307" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60307" } ] } ] }, { "uniprot_ac": "O60566", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O60566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60566" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O60566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60566" } ] } ] }, { "uniprot_ac": "O61122", "gene_name": "svkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61122" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61122" } ] } ] }, { "uniprot_ac": "O61125", "gene_name": "krsA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61125" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61125" } ] } ] }, { "uniprot_ac": "O61267", "gene_name": "lok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61267" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61443" } ] } ] }, { "uniprot_ac": "O61444", "gene_name": "Mkk4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61444" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O61444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61444" } ] } ] }, { "uniprot_ac": "O61661", "gene_name": "grp", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61661" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O61661" } ] } ] }, { "uniprot_ac": "O62602", "gene_name": "lic", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O62602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62602" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "O62602", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62602" } ] } ] }, { "uniprot_ac": "O62618", "gene_name": "p38a", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O62618" } ] } ] }, { "uniprot_ac": "O70126", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70126" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70126" } ] } ] }, { "uniprot_ac": "O70146", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70146" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "O70146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70146" } ] } ] }, { "uniprot_ac": "O70150", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70150" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "O70150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70150" } ] } ] }, { "uniprot_ac": "O70405", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70405" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70405" } ] } ] }, { "uniprot_ac": "O70444", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70444" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70444" } ] } ] }, { "uniprot_ac": "O70551", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70551" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70551" } ] } ] }, { "uniprot_ac": "O70589", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O70589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70589" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O70589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70589" } ] } ] }, { "uniprot_ac": "O75116", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75116" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75116" } ] } ] }, { "uniprot_ac": "O75385", "gene_name": "ULK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75385" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75385", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75385" } ] } ] }, { "uniprot_ac": "O75460", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "O75460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75460" } ] } ] }, { "uniprot_ac": "O75582", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75582", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75582" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75582", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75582" } ] } ] }, { "uniprot_ac": "O75676", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75676" } ] } ] }, { "uniprot_ac": "O75716", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O75716", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75716" } ] } ] }, { "uniprot_ac": "O75914", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75914" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75914" } ] } ] }, { "uniprot_ac": "O75962", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O75962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O75962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75962" } ] } ] }, { "uniprot_ac": "O76039", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O76039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76039" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O76039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76039" } ] } ] }, { "uniprot_ac": "O76324", "gene_name": "dco", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76324" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O76324" } ] } ] }, { "uniprot_ac": "O88351", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88351" } ] } ] }, { "uniprot_ac": "O88445", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88445" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88445" } ] } ] }, { "uniprot_ac": "O88506", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88506" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88506" } ] } ] }, { "uniprot_ac": "O88643", "gene_name": "Pak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88643" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88643" } ] } ] }, { "uniprot_ac": "O88664", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88664" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88664" } ] } ] }, { "uniprot_ac": "O88697", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "O88697", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88697" } ] } ] }, { "uniprot_ac": "O88764", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88764" } ] } ] }, { "uniprot_ac": "O88831", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88831" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "O88831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88831" } ] } ] }, { "uniprot_ac": "O88850", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88850" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88850" } ] } ] }, { "uniprot_ac": "O88866", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88866" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88866" } ] } ] }, { "uniprot_ac": "O88904", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O88904", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88904" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O88904", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O88904" } ] } ] }, { "uniprot_ac": "O94768", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94768" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O94768", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94768" } ] } ] }, { "uniprot_ac": "O94804", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94804" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O94804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94804" } ] } ] }, { "uniprot_ac": "O94806", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94806" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "O94806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94806" } ] } ] }, { "uniprot_ac": "O94921", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O94921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94921" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O94921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O94921" } ] } ] }, { "uniprot_ac": "O95382", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95382" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "O95382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95382" } ] } ] }, { "uniprot_ac": "O95747", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95747" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95747" } ] } ] }, { "uniprot_ac": "O95819", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95819" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95819", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95819" } ] } ] }, { "uniprot_ac": "O95835", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O95835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95835" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O95835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O95835" } ] } ] }, { "uniprot_ac": "O96013", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O96013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96013" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O96013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96013" } ] } ] }, { "uniprot_ac": "O96017", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O96017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96017" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O96017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O96017" } ] } ] }, { "uniprot_ac": "O97143", "gene_name": "SAK", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97143" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O97143" } ] } ] }, { "uniprot_ac": "P00536", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00536" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00536" } ] } ] }, { "uniprot_ac": "P00539", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00539" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00539" } ] } ] }, { "uniprot_ac": "P00540", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P00540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00540" } ] } ] }, { "uniprot_ac": "P00546", "gene_name": "CDC28", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P00546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00546" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P00546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00546" } ] } ] }, { "uniprot_ac": "P04049", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04049" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04049" } ] } ] }, { "uniprot_ac": "P04627", "gene_name": "Araf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P04627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04627" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P04627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04627" } ] } ] }, { "uniprot_ac": "P05129", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05129" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05129" } ] } ] }, { "uniprot_ac": "P05130", "gene_name": "Pkc53E", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05130" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05130" } ] } ] }, { "uniprot_ac": "P05132", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05132" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05132" } ] } ] }, { "uniprot_ac": "P05696", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05696" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05696" } ] } ] }, { "uniprot_ac": "P05771", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05771" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05771" } ] } ] }, { "uniprot_ac": "P05986", "gene_name": "TPK3", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P05986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05986" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P05986" } ] } ] }, { "uniprot_ac": "P06243", "gene_name": "CDC7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06243" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06243" } ] } ] }, { "uniprot_ac": "P06244", "gene_name": "TPK1", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06244" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P06244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06244" } ] } ] }, { "uniprot_ac": "P06245", "gene_name": "TPK2", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06245" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P06245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06245" } ] } ] }, { "uniprot_ac": "P06493", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P06493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06493" } ] } ] }, { "uniprot_ac": "P06782", "gene_name": "SNF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06782" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06782" } ] } ] }, { "uniprot_ac": "P06784", "gene_name": "STE7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06784" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P06784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06784" } ] } ] }, { "uniprot_ac": "P06803", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P06803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06803" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P06803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06803" } ] } ] }, { "uniprot_ac": "P07934", "gene_name": "Phkg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P07934", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07934" } ] } ] }, { "uniprot_ac": "P08018", "gene_name": "PBS2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08018" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P08018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08018" } ] } ] }, { "uniprot_ac": "P08181", "gene_name": "CkIIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08181" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08181" } ] } ] }, { "uniprot_ac": "P08413", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08413" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P08413", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08413" } ] } ] }, { "uniprot_ac": "P08414", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08414" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P08414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08414" } ] } ] }, { "uniprot_ac": "P08458", "gene_name": "SPS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P08458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08458" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08458" } ] } ] }, { "uniprot_ac": "P09215", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09215", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09215" } ] } ] }, { "uniprot_ac": "P09216", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09216" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09216" } ] } ] }, { "uniprot_ac": "P09217", "gene_name": "Prkcz", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P09217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09217" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P09217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09217" } ] } ] }, { "uniprot_ac": "P0C0R5", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C0R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C0R5" } ] } ] }, { "uniprot_ac": "P0C1X8", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C1X8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C1X8" } ] } ] }, { "uniprot_ac": "P0C263", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C263" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C263" } ] } ] }, { "uniprot_ac": "P0C264", "gene_name": "SBK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C264" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C264", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C264" } ] } ] }, { "uniprot_ac": "P0C5K0", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K0" } ] } ] }, { "uniprot_ac": "P0C5K1", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0C5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C5K1" } ] } ] }, { "uniprot_ac": "P0C605", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C605" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P0C605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C605" } ] } ] }, { "uniprot_ac": "P0C865", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C865", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C865" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P0C865", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C865" } ] } ] }, { "uniprot_ac": "P0C8E4", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0C8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C8E4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P0C8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C8E4" } ] } ] }, { "uniprot_ac": "P0CD62", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P0CD62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CD62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P0CD62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CD62" } ] } ] }, { "uniprot_ac": "P10398", "gene_name": "ARAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P10398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10398" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10398" } ] } ] }, { "uniprot_ac": "P10676", "gene_name": "ninaC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10676" } ] } ] }, { "uniprot_ac": "P11274", "gene_name": "BCR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11274" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11274", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11274" } ] } ] }, { "uniprot_ac": "P11275", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11275" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11275" } ] } ] }, { "uniprot_ac": "P11309", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11309" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11309", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11309" } ] } ] }, { "uniprot_ac": "P11345", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11345" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11345" } ] } ] }, { "uniprot_ac": "P11346", "gene_name": "Raf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11346" } ] } ] }, { "uniprot_ac": "P11440", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P11440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11440" } ] } ] }, { "uniprot_ac": "P11730", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11730" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11730" } ] } ] }, { "uniprot_ac": "P11792", "gene_name": "SCH9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11792" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11792" } ] } ] }, { "uniprot_ac": "P11798", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11798" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P11798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11798" } ] } ] }, { "uniprot_ac": "P11801", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11801" } ] } ] }, { "uniprot_ac": "P11802", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11802" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P11802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11802" } ] } ] }, { "uniprot_ac": "P11980", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P11980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11980" } ] } ] }, { "uniprot_ac": "P12370", "gene_name": "Pka-C1", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12370" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12370" } ] } ] }, { "uniprot_ac": "P12688", "gene_name": "YPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P12688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12688" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P12688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P12688" } ] } ] }, { "uniprot_ac": "P13185", "gene_name": "KIN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P13185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13185" } ] } ] }, { "uniprot_ac": "P13186", "gene_name": "KIN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13186" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P13186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13186" } ] } ] }, { "uniprot_ac": "P13234", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13234" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P13234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13234" } ] } ] }, { "uniprot_ac": "P13286", "gene_name": "Phkg1", "activity": [ { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P13286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13286" } ] } ] }, { "uniprot_ac": "P13677", "gene_name": "inaC", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13677" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13677" } ] } ] }, { "uniprot_ac": "P13678", "gene_name": "Pkc98E", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13678" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13678" } ] } ] }, { "uniprot_ac": "P14056", "gene_name": "Araf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14056" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P14056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14056" } ] } ] }, { "uniprot_ac": "P14618", "gene_name": "PKM", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14618" } ] } ] }, { "uniprot_ac": "P14680", "gene_name": "YAK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14680" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14680" } ] } ] }, { "uniprot_ac": "P14681", "gene_name": "KSS1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P14681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14681" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P14681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14681" } ] } ] }, { "uniprot_ac": "P15056", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15056" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15056" } ] } ] }, { "uniprot_ac": "P15442", "gene_name": "GCN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15442" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15442" } ] } ] }, { "uniprot_ac": "P15790", "gene_name": "CKA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15790" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P15790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15790" } ] } ] }, { "uniprot_ac": "P15791", "gene_name": "Camk2d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P15791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15791" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P15791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15791" } ] } ] }, { "uniprot_ac": "P16054", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16054" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P16054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16054" } ] } ] }, { "uniprot_ac": "P16892", "gene_name": "FUS3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16892" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P16892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16892" } ] } ] }, { "uniprot_ac": "P16911", "gene_name": "Pka-C2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16911" } ] } ] }, { "uniprot_ac": "P16912", "gene_name": "Pka-C3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16912" } ] } ] }, { "uniprot_ac": "P17157", "gene_name": "PHO85", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17157" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P17157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17157" } ] } ] }, { "uniprot_ac": "P17252", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17252" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P17252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17252" } ] } ] }, { "uniprot_ac": "P17612", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P17612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17612" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P17612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P17612" } ] } ] }, { "uniprot_ac": "P18265", "gene_name": "Gsk3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P18265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18265" } ] } ] }, { "uniprot_ac": "P18266", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18266" } ] } ] }, { "uniprot_ac": "P18431", "gene_name": "sgg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18431" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18431" } ] } ] }, { "uniprot_ac": "P18653", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18653", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18653" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18653", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18653" } ] } ] }, { "uniprot_ac": "P18654", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18654" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18654", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18654" } ] } ] }, { "uniprot_ac": "P18961", "gene_name": "YPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P18961", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18961" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18961", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P18961" } ] } ] }, { "uniprot_ac": "P19139", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19139" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19139" } ] } ] }, { "uniprot_ac": "P19454", "gene_name": "CKA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19454" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19454" } ] } ] }, { "uniprot_ac": "P19525", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19525" } ] } ] }, { "uniprot_ac": "P19784", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P19784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19784" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P19784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P19784" } ] } ] }, { "uniprot_ac": "P20444", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20444" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P20444", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20444" } ] } ] }, { "uniprot_ac": "P20793", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20793" } ] } ] }, { "uniprot_ac": "P20794", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P20794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20794" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P20794" } ] } ] }, { "uniprot_ac": "P21127", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21127" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P21127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21127" } ] } ] }, { "uniprot_ac": "P21675", "gene_name": "TAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "P21675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21675" } ] } ] }, { "uniprot_ac": "P21708", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21708" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P21708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21708" } ] } ] }, { "uniprot_ac": "P21965", "gene_name": "MCK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P21965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21965" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P21965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21965" } ] } ] }, { "uniprot_ac": "P22204", "gene_name": "DBF2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22204" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22204" } ] } ] }, { "uniprot_ac": "P22209", "gene_name": "KIN3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22209" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22209" } ] } ] }, { "uniprot_ac": "P22211", "gene_name": "NPR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22211", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22211" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22211", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22211" } ] } ] }, { "uniprot_ac": "P22216", "gene_name": "RAD53", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22216" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P22216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22216" } ] } ] }, { "uniprot_ac": "P22219", "gene_name": "VPS15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22219", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22219" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P22219", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22219" } ] } ] }, { "uniprot_ac": "P22517", "gene_name": "CMK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22517" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P22517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22517" } ] } ] }, { "uniprot_ac": "P22518", "gene_name": "Clk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22518" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P22518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22518" } ] } ] }, { "uniprot_ac": "P22612", "gene_name": "PRKACG", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22612" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P22612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22612" } ] } ] }, { "uniprot_ac": "P22694", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P22694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22694" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P22694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P22694" } ] } ] }, { "uniprot_ac": "P23291", "gene_name": "YCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23291", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23291" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23291", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23291" } ] } ] }, { "uniprot_ac": "P23292", "gene_name": "YCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23292" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23292" } ] } ] }, { "uniprot_ac": "P23293", "gene_name": "SGV1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23293", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23293" } ] } ] }, { "uniprot_ac": "P23298", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23298" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P23298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23298" } ] } ] }, { "uniprot_ac": "P23443", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23443" } ] } ] }, { "uniprot_ac": "P23561", "gene_name": "STE11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23561" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P23561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23561" } ] } ] }, { "uniprot_ac": "P23572", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23572" } ] } ] }, { "uniprot_ac": "P23573", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23573" } ] } ] }, { "uniprot_ac": "P23647", "gene_name": "fu", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23647" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P23647" } ] } ] }, { "uniprot_ac": "P24583", "gene_name": "PKC1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24583" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P24583", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24583" } ] } ] }, { "uniprot_ac": "P24719", "gene_name": "MEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24719" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P24719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24719" } ] } ] }, { "uniprot_ac": "P24723", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24723" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P24723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24723" } ] } ] }, { "uniprot_ac": "P24788", "gene_name": "Cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24788", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24788" } ] } ] }, { "uniprot_ac": "P24941", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P24941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24941" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P24941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P24941" } ] } ] }, { "uniprot_ac": "P25333", "gene_name": "SAT4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25333" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25333" } ] } ] }, { "uniprot_ac": "P25341", "gene_name": "KIN82", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25341", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25341" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25341", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25341" } ] } ] }, { "uniprot_ac": "P25389", "gene_name": "KCC4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25389" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25389" } ] } ] }, { "uniprot_ac": "P25390", "gene_name": "SSK22", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P25390", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25390" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P25390", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25390" } ] } ] }, { "uniprot_ac": "P26794", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P26794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26794" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P26794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26794" } ] } ] }, { "uniprot_ac": "P27361", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27361" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P27361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27361" } ] } ] }, { "uniprot_ac": "P27448", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27448" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P27448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27448" } ] } ] }, { "uniprot_ac": "P27466", "gene_name": "CMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27466" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P27466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27466" } ] } ] }, { "uniprot_ac": "P27636", "gene_name": "CDC15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27636" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P27636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27636" } ] } ] }, { "uniprot_ac": "P27704", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27704" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P27704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27704" } ] } ] }, { "uniprot_ac": "P27791", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P27791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27791" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P27791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P27791" } ] } ] }, { "uniprot_ac": "P28028", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28028" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28028" } ] } ] }, { "uniprot_ac": "P28178", "gene_name": "pkgB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28178" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28178", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28178" } ] } ] }, { "uniprot_ac": "P28482", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28482" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P28482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28482" } ] } ] }, { "uniprot_ac": "P28652", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28652" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P28652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28652" } ] } ] }, { "uniprot_ac": "P28708", "gene_name": "PRR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28708" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P28708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28708" } ] } ] }, { "uniprot_ac": "P28867", "gene_name": "Prkcd", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] }, { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P28867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28867" } ] } ] }, { "uniprot_ac": "P29295", "gene_name": "HRR25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P29295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29295" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P29295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P29295" } ] } ] }, { "uniprot_ac": "P30285", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P30285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30285" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P30285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P30285" } ] } ] }, { "uniprot_ac": "P31152", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31152" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P31152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31152" } ] } ] }, { "uniprot_ac": "P31374", "gene_name": "PSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31374" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31374" } ] } ] }, { "uniprot_ac": "P31749", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31749" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31749" } ] } ] }, { "uniprot_ac": "P31750", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31750" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31750" } ] } ] }, { "uniprot_ac": "P31751", "gene_name": "AKT2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31751" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P31751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31751" } ] } ] }, { "uniprot_ac": "P31938", "gene_name": "Map2k1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P31938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31938" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P31938", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31938" } ] } ] }, { "uniprot_ac": "P32328", "gene_name": "DBF20", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32328" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32328", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32328" } ] } ] }, { "uniprot_ac": "P32350", "gene_name": "KNS1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32350" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P32350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32350" } ] } ] }, { "uniprot_ac": "P32361", "gene_name": "IRE1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32361" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "P32361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32361" } ] } ] }, { "uniprot_ac": "P32485", "gene_name": "HOG1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32485" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P32485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32485" } ] } ] }, { "uniprot_ac": "P32490", "gene_name": "MKK1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32490" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P32490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32490" } ] } ] }, { "uniprot_ac": "P32491", "gene_name": "MKK2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32491" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P32491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32491" } ] } ] }, { "uniprot_ac": "P32562", "gene_name": "CDC5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32562" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P32562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32562" } ] } ] }, { "uniprot_ac": "P32581", "gene_name": "IME2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32581" } ] } ] }, { "uniprot_ac": "P32600", "gene_name": "TOR2", "activity": [ { "ec_number": "2.7.1.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.1.67", "activity": "", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32600" } ] } ] }, { "uniprot_ac": "P32789", "gene_name": "ALK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32789", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32789" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32789", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32789" } ] } ] }, { "uniprot_ac": "P32801", "gene_name": "ELM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32801" } ] } ] }, { "uniprot_ac": "P32944", "gene_name": "SWE1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P32944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32944" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P32944" } ] } ] }, { "uniprot_ac": "P33076", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P33076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33076" } ] } ] }, { "uniprot_ac": "P33981", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P33981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33981" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P33981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33981" } ] } ] }, { "uniprot_ac": "P34099", "gene_name": "pkaC", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34099" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P34099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34099" } ] } ] }, { "uniprot_ac": "P34100", "gene_name": "pkaD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34100" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34100" } ] } ] }, { "uniprot_ac": "P34101", "gene_name": "fhkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34101" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34101" } ] } ] }, { "uniprot_ac": "P34102", "gene_name": "pkgC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34102" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34102" } ] } ] }, { "uniprot_ac": "P34103", "gene_name": "pkgD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34103" } ] } ] }, { "uniprot_ac": "P34112", "gene_name": "cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P34112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34112" } ] } ] }, { "uniprot_ac": "P34117", "gene_name": "cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34117" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P34117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34117" } ] } ] }, { "uniprot_ac": "P34244", "gene_name": "HSL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P34244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34244" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P34244", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34244" } ] } ] }, { "uniprot_ac": "P35169", "gene_name": "TOR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35169", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35169" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35169", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35169" } ] } ] }, { "uniprot_ac": "P35426", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35426", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35426" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P35426", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35426" } ] } ] }, { "uniprot_ac": "P35465", "gene_name": "Pak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35465" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35465" } ] } ] }, { "uniprot_ac": "P35761", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P35761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35761" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P35761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P35761" } ] } ] }, { "uniprot_ac": "P36002", "gene_name": "PTK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36002" } ] } ] }, { "uniprot_ac": "P36003", "gene_name": "NNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36003" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36003" } ] } ] }, { "uniprot_ac": "P36004", "gene_name": "KKQ8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36004" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36004" } ] } ] }, { "uniprot_ac": "P36005", "gene_name": "KDX1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36005" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P36005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36005" } ] } ] }, { "uniprot_ac": "P36506", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36506" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P36506", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36506" } ] } ] }, { "uniprot_ac": "P36507", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P36507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36507" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P36507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P36507" } ] } ] }, { "uniprot_ac": "P38070", "gene_name": "YPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38070" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38070" } ] } ] }, { "uniprot_ac": "P38080", "gene_name": "AKL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38080" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38080" } ] } ] }, { "uniprot_ac": "P38110", "gene_name": "TEL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38110" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38110", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38110" } ] } ] }, { "uniprot_ac": "P38111", "gene_name": "MEC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38111" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38111" } ] } ] }, { "uniprot_ac": "P38147", "gene_name": "CHK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38147" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38147" } ] } ] }, { "uniprot_ac": "P38615", "gene_name": "RIM11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38615" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38615" } ] } ] }, { "uniprot_ac": "P38622", "gene_name": "RCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38622" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38622" } ] } ] }, { "uniprot_ac": "P38623", "gene_name": "RCK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38623" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38623", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38623" } ] } ] }, { "uniprot_ac": "P38691", "gene_name": "KSP1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38691" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38691" } ] } ] }, { "uniprot_ac": "P38692", "gene_name": "KIC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38692" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38692" } ] } ] }, { "uniprot_ac": "P38970", "gene_name": "HAL5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38970" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38970" } ] } ] }, { "uniprot_ac": "P38990", "gene_name": "SAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38990" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38990" } ] } ] }, { "uniprot_ac": "P38991", "gene_name": "IPL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P38991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38991" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P38991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P38991" } ] } ] }, { "uniprot_ac": "P39009", "gene_name": "DUN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39009" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P39009", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39009" } ] } ] }, { "uniprot_ac": "P39073", "gene_name": "SSN3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P39073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39073" } ] } ] }, { "uniprot_ac": "P39951", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P39951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39951" } ] } ] }, { "uniprot_ac": "P39962", "gene_name": "YCK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P39962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P39962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39962" } ] } ] }, { "uniprot_ac": "P40160", "gene_name": "RIO2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40160" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P40160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40160" } ] } ] }, { "uniprot_ac": "P40417", "gene_name": "rl", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40417" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40417" } ] } ] }, { "uniprot_ac": "P40494", "gene_name": "PRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P40494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40494" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P40494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P40494" } ] } ] }, { "uniprot_ac": "P41279", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P41279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41279" } ] } ] }, { "uniprot_ac": "P41695", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41695" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P41695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41695" } ] } ] }, { "uniprot_ac": "P41743", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41743" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P41743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41743" } ] } ] }, { "uniprot_ac": "P41808", "gene_name": "SMK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P41808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41808" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P41808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P41808" } ] } ] }, { "uniprot_ac": "P42336", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42336" } ] } ] }, { "uniprot_ac": "P42337", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42337", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42337" } ] } ] }, { "uniprot_ac": "P42338", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P42338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42338" } ] } ] }, { "uniprot_ac": "P42345", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42345" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P42345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42345" } ] } ] }, { "uniprot_ac": "P42346", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P42346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42346" } ] } ] }, { "uniprot_ac": "P42525", "gene_name": "erkA", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P42525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42525" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P42525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P42525" } ] } ] }, { "uniprot_ac": "P43565", "gene_name": "RIM15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43565" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43565", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43565" } ] } ] }, { "uniprot_ac": "P43568", "gene_name": "CAK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43568" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P43568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43568" } ] } ] }, { "uniprot_ac": "P43633", "gene_name": "ALK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43633" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43633" } ] } ] }, { "uniprot_ac": "P43637", "gene_name": "TOS3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P43637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43637" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P43637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P43637" } ] } ] }, { "uniprot_ac": "P45983", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45983" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P45983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45983" } ] } ] }, { "uniprot_ac": "P45984", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45984" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P45984", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45984" } ] } ] }, { "uniprot_ac": "P45985", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P45985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45985" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P45985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P45985" } ] } ] }, { "uniprot_ac": "P46734", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P46734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46734" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P46734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46734" } ] } ] }, { "uniprot_ac": "P46892", "gene_name": "Cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P46892", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46892" } ] } ] }, { "uniprot_ac": "P47042", "gene_name": "IKS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47042" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47042" } ] } ] }, { "uniprot_ac": "P47116", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47116" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47116" } ] } ] }, { "uniprot_ac": "P47196", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47196" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47196" } ] } ] }, { "uniprot_ac": "P47197", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47197" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P47197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47197" } ] } ] }, { "uniprot_ac": "P47809", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47809" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P47809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47809" } ] } ] }, { "uniprot_ac": "P47811", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P47811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47811" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P47811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47811" } ] } ] }, { "uniprot_ac": "P48562", "gene_name": "CLA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48562" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48562" } ] } ] }, { "uniprot_ac": "P48609", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48609" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48609" } ] } ] }, { "uniprot_ac": "P48729", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48729" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48729" } ] } ] }, { "uniprot_ac": "P48730", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P48730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48730" } ] } ] }, { "uniprot_ac": "P48736", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "P48736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48736" } ] } ] }, { "uniprot_ac": "P49025", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49025" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49025", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49025" } ] } ] }, { "uniprot_ac": "P49071", "gene_name": "MAPk-Ak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49071" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49071" } ] } ] }, { "uniprot_ac": "P49137", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49137" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49137" } ] } ] }, { "uniprot_ac": "P49138", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49138" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49138" } ] } ] }, { "uniprot_ac": "P49185", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49185" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49185" } ] } ] }, { "uniprot_ac": "P49186", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49186" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49186" } ] } ] }, { "uniprot_ac": "P49187", "gene_name": "Mapk10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49187" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P49187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49187" } ] } ] }, { "uniprot_ac": "P49336", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P49336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49336" } ] } ] }, { "uniprot_ac": "P49615", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49615" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49615" } ] } ] }, { "uniprot_ac": "P49657", "gene_name": "mnb", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49657" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49657" } ] } ] }, { "uniprot_ac": "P49674", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49674" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49674" } ] } ] }, { "uniprot_ac": "P49759", "gene_name": "CLK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49759" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49759" } ] } ] }, { "uniprot_ac": "P49760", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49760" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49760" } ] } ] }, { "uniprot_ac": "P49761", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49761" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49761" } ] } ] }, { "uniprot_ac": "P49762", "gene_name": "Doa", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49762" } ] } ] }, { "uniprot_ac": "P49840", "gene_name": "GSK3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P49840", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49840" } ] } ] }, { "uniprot_ac": "P49841", "gene_name": "GSK3B", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P49841", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P49841" } ] } ] }, { "uniprot_ac": "P50613", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P50613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50613" } ] } ] }, { "uniprot_ac": "P50750", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P50750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50750" } ] } ] }, { "uniprot_ac": "P50873", "gene_name": "MRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P50873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50873" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P50873", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P50873" } ] } ] }, { "uniprot_ac": "P51123", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51123" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51123" } ] } ] }, { "uniprot_ac": "P51617", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51617" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51617" } ] } ] }, { "uniprot_ac": "P51812", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51812", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51812" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51812", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51812" } ] } ] }, { "uniprot_ac": "P51817", "gene_name": "PRKX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51817" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51817" } ] } ] }, { "uniprot_ac": "P51952", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P51952", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51952" } ] } ] }, { "uniprot_ac": "P51954", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51954" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51954" } ] } ] }, { "uniprot_ac": "P51955", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51955" } ] } ] }, { "uniprot_ac": "P51956", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51956" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51956" } ] } ] }, { "uniprot_ac": "P51957", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P51957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51957" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P51957" } ] } ] }, { "uniprot_ac": "P52304", "gene_name": "polo", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52304" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52304" } ] } ] }, { "uniprot_ac": "P52480", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52480", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52480" } ] } ] }, { "uniprot_ac": "P52564", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P52564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52564" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P52564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52564" } ] } ] }, { "uniprot_ac": "P53104", "gene_name": "ATG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53104" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53104" } ] } ] }, { "uniprot_ac": "P53233", "gene_name": "FMP48", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53233" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53233" } ] } ] }, { "uniprot_ac": "P53323", "gene_name": "BUD32", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53323" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "P53323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53323" } ] } ] }, { "uniprot_ac": "P53349", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53349" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P53349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53349" } ] } ] }, { "uniprot_ac": "P53350", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53350" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P53350", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53350" } ] } ] }, { "uniprot_ac": "P53351", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53351" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P53351", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53351" } ] } ] }, { "uniprot_ac": "P53355", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53355" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53355" } ] } ] }, { "uniprot_ac": "P53599", "gene_name": "SSK2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53599" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P53599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53599" } ] } ] }, { "uniprot_ac": "P53667", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53667" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53667", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53667" } ] } ] }, { "uniprot_ac": "P53668", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53668", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53668" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53668", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53668" } ] } ] }, { "uniprot_ac": "P53669", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53669", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53669" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53669", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53669" } ] } ] }, { "uniprot_ac": "P53670", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53670" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53670" } ] } ] }, { "uniprot_ac": "P53671", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53671", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53671" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53671", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53671" } ] } ] }, { "uniprot_ac": "P53739", "gene_name": "FPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53739" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53739" } ] } ] }, { "uniprot_ac": "P53778", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53778" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P53778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53778" } ] } ] }, { "uniprot_ac": "P53779", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53779" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P53779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53779" } ] } ] }, { "uniprot_ac": "P53894", "gene_name": "CBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53894", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53894" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53894", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53894" } ] } ] }, { "uniprot_ac": "P53974", "gene_name": "ARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P53974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53974" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P53974" } ] } ] }, { "uniprot_ac": "P54199", "gene_name": "MPS1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54199" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P54199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54199" } ] } ] }, { "uniprot_ac": "P54265", "gene_name": "Dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54265" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54265" } ] } ] }, { "uniprot_ac": "P54360", "gene_name": "fj", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54360" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54360" } ] } ] }, { "uniprot_ac": "P54367", "gene_name": "CkIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54367" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54367" } ] } ] }, { "uniprot_ac": "P54644", "gene_name": "pkbA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54644" } ] } ] }, { "uniprot_ac": "P54645", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "P54645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54645" } ] } ] }, { "uniprot_ac": "P54646", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54646" } ] } ] }, { "uniprot_ac": "P54685", "gene_name": "cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P54685", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54685" } ] } ] }, { "uniprot_ac": "P57058", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57058" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57058", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57058" } ] } ] }, { "uniprot_ac": "P57059", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57059" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57059" } ] } ] }, { "uniprot_ac": "P57078", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57078" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57078" } ] } ] }, { "uniprot_ac": "P57760", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P57760", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57760" } ] } ] }, { "uniprot_ac": "P58750", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P58750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58750" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P58750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58750" } ] } ] }, { "uniprot_ac": "P58801", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P58801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P58801" } ] } ] }, { "uniprot_ac": "P59241", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P59241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P59241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59241" } ] } ] }, { "uniprot_ac": "P59895", "gene_name": "Nek6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P59895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59895" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "P59895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P59895" } ] } ] }, { "uniprot_ac": "P63085", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63085" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P63085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63085" } ] } ] }, { "uniprot_ac": "P63086", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63086" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P63086", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63086" } ] } ] }, { "uniprot_ac": "P63318", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63318" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P63318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63318" } ] } ] }, { "uniprot_ac": "P63319", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P63319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63319" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P63319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63319" } ] } ] }, { "uniprot_ac": "P67999", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P67999", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67999" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67999", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P67999" } ] } ] }, { "uniprot_ac": "P68181", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68181" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68181" } ] } ] }, { "uniprot_ac": "P68182", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68182" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68182" } ] } ] }, { "uniprot_ac": "P68400", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68400" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68400" } ] } ] }, { "uniprot_ac": "P68403", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68403" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P68403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68403" } ] } ] }, { "uniprot_ac": "P68404", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P68404", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68404" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P68404", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68404" } ] } ] }, { "uniprot_ac": "P70218", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70218" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70218" } ] } ] }, { "uniprot_ac": "P70236", "gene_name": "Map2k6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70236" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "P70236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70236" } ] } ] }, { "uniprot_ac": "P70268", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70268" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P70268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70268" } ] } ] }, { "uniprot_ac": "P70335", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70335" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70335" } ] } ] }, { "uniprot_ac": "P70336", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70336" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P70336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70336" } ] } ] }, { "uniprot_ac": "P70618", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P70618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P70618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70618" } ] } ] }, { "uniprot_ac": "P78362", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78362" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78362" } ] } ] }, { "uniprot_ac": "P78368", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78368" } ] } ] }, { "uniprot_ac": "P78527", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P78527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78527" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P78527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P78527" } ] } ] }, { "uniprot_ac": "P79621", "gene_name": "Ciita", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P79621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P79621" } ] } ] }, { "uniprot_ac": "P80192", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P80192", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80192" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P80192", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P80192" } ] } ] }, { "uniprot_ac": "P83098", "gene_name": "Stlk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83098" } ] } ] }, { "uniprot_ac": "P83099", "gene_name": "Pkcdelta", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83099" } ] } ] }, { "uniprot_ac": "P83100", "gene_name": "p38c", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83100" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83100" } ] } ] }, { "uniprot_ac": "P83102", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83102" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83102" } ] } ] }, { "uniprot_ac": "P83103", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83103" } ] } ] }, { "uniprot_ac": "P83104", "gene_name": "Takl1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83104" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83104" } ] } ] }, { "uniprot_ac": "P83510", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83510" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83510", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83510" } ] } ] }, { "uniprot_ac": "P83741", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P83741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P83741" } ] } ] }, { "uniprot_ac": "P92208", "gene_name": "bsk", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P92208" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P92208" } ] } ] }, { "uniprot_ac": "P97313", "gene_name": "Prkdc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97313" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97313", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97313" } ] } ] }, { "uniprot_ac": "P97343", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97343" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97343" } ] } ] }, { "uniprot_ac": "P97377", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97377", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97377" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P97377", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97377" } ] } ] }, { "uniprot_ac": "P97477", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97477", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97477" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97477", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97477" } ] } ] }, { "uniprot_ac": "P97633", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97633" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97633" } ] } ] }, { "uniprot_ac": "P97756", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "P97756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97756" } ] } ] }, { "uniprot_ac": "P97820", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97820", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97820" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97820", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97820" } ] } ] }, { "uniprot_ac": "P97874", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97874" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97874", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97874" } ] } ] }, { "uniprot_ac": "P97924", "gene_name": "Kalrn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "P97924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97924" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P97924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97924" } ] } ] }, { "uniprot_ac": "Q00168", "gene_name": "CaMKII", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00168" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00168" } ] } ] }, { "uniprot_ac": "Q00526", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00526" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00526" } ] } ] }, { "uniprot_ac": "Q00532", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00532" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00532" } ] } ] }, { "uniprot_ac": "Q00534", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00534" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00534" } ] } ] }, { "uniprot_ac": "Q00535", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00535" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q00535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00535" } ] } ] }, { "uniprot_ac": "Q00536", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00536" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00536" } ] } ] }, { "uniprot_ac": "Q00537", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00537" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q00537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00537" } ] } ] }, { "uniprot_ac": "Q00772", "gene_name": "SLT2", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00772" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q00772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00772" } ] } ] }, { "uniprot_ac": "Q00972", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.7.11.4", "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q00972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00972" } ] } ] }, { "uniprot_ac": "Q00987", "gene_name": "MDM2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q00987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00987" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q00987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q00987" } ] } ] }, { "uniprot_ac": "Q01389", "gene_name": "BCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01389" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01389", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01389" } ] } ] }, { "uniprot_ac": "Q01919", "gene_name": "KIN4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01919" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01919", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01919" } ] } ] }, { "uniprot_ac": "Q01986", "gene_name": "Map2k1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q01986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01986" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q01986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q01986" } ] } ] }, { "uniprot_ac": "Q02111", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02111" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02111" } ] } ] }, { "uniprot_ac": "Q02156", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02156" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02156" } ] } ] }, { "uniprot_ac": "Q02720", "gene_name": "casK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02720" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02720" } ] } ] }, { "uniprot_ac": "Q02750", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02750" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q02750", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02750" } ] } ] }, { "uniprot_ac": "Q02779", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02779" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q02779", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02779" } ] } ] }, { "uniprot_ac": "Q02956", "gene_name": "Prkcz", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q02956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02956" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q02956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q02956" } ] } ] }, { "uniprot_ac": "Q03002", "gene_name": "FRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03002" } ] } ] }, { "uniprot_ac": "Q03042", "gene_name": "Pkg21D", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03042" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03042" } ] } ] }, { "uniprot_ac": "Q03043", "gene_name": "for", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03043" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03043" } ] } ] }, { "uniprot_ac": "Q03114", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03114", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03114" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03114", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03114" } ] } ] }, { "uniprot_ac": "Q03141", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03141" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03141" } ] } ] }, { "uniprot_ac": "Q03147", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q03147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03147" } ] } ] }, { "uniprot_ac": "Q03306", "gene_name": "PKH3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03306" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03306" } ] } ] }, { "uniprot_ac": "Q03407", "gene_name": "PKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03407" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03407" } ] } ] }, { "uniprot_ac": "Q03497", "gene_name": "STE20", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03497" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03497" } ] } ] }, { "uniprot_ac": "Q03533", "gene_name": "TDA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03533" } ] } ] }, { "uniprot_ac": "Q03656", "gene_name": "SKY1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03656" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03656" } ] } ] }, { "uniprot_ac": "Q03785", "gene_name": "VHS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03785" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03785" } ] } ] }, { "uniprot_ac": "Q03963", "gene_name": "Eif2ak2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q03963", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03963" } ] } ] }, { "uniprot_ac": "Q04735", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04735" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q04735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04735" } ] } ] }, { "uniprot_ac": "Q04759", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04759" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q04759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04759" } ] } ] }, { "uniprot_ac": "Q04859", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04859", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04859" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04859", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04859" } ] } ] }, { "uniprot_ac": "Q04899", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q04899", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04899" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q04899", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04899" } ] } ] }, { "uniprot_ac": "Q05512", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q05512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05512" } ] } ] }, { "uniprot_ac": "Q05513", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05513" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q05513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05513" } ] } ] }, { "uniprot_ac": "Q05652", "gene_name": "pll", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05652" } ] } ] }, { "uniprot_ac": "Q05655", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] }, { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q05655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05655" } ] } ] }, { "uniprot_ac": "Q06098", "gene_name": "ISR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06098" } ] } ] }, { "uniprot_ac": "Q06226", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06226" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06226" } ] } ] }, { "uniprot_ac": "Q06486", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q06486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06486" } ] } ] }, { "uniprot_ac": "Q07002", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07002" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q07002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07002" } ] } ] }, { "uniprot_ac": "Q07174", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07174" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q07174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07174" } ] } ] }, { "uniprot_ac": "Q07832", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07832" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q07832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07832" } ] } ] }, { "uniprot_ac": "Q07912", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q07912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07912" } ] } ] }, { "uniprot_ac": "Q08217", "gene_name": "PSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q08217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08217" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08217" } ] } ] }, { "uniprot_ac": "Q08732", "gene_name": "HRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q08732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08732" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08732", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q08732" } ] } ] }, { "uniprot_ac": "Q09013", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q09013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09013" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q09013", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09013" } ] } ] }, { "uniprot_ac": "Q09137", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q09137", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q09137" } ] } ] }, { "uniprot_ac": "Q0KHQ5", "gene_name": "Tao", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHQ5" } ] } ] }, { "uniprot_ac": "Q0KHT7", "gene_name": "Drak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHT7" } ] } ] }, { "uniprot_ac": "Q0KHV6", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KHV6" } ] } ] }, { "uniprot_ac": "Q0KL02", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q0KL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KL02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KL02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q0KL02" } ] } ] }, { "uniprot_ac": "Q12003", "gene_name": "ENV7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12003" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12003" } ] } ] }, { "uniprot_ac": "Q12100", "gene_name": "RTK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12100" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12100" } ] } ] }, { "uniprot_ac": "Q12152", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12152" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12152" } ] } ] }, { "uniprot_ac": "Q12196", "gene_name": "RIO1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12196" } ] } ] }, { "uniprot_ac": "Q12222", "gene_name": "YGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12222" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12222", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12222" } ] } ] }, { "uniprot_ac": "Q12236", "gene_name": "PKH2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12236" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12236" } ] } ] }, { "uniprot_ac": "Q12263", "gene_name": "GIN4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12263" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12263", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12263" } ] } ] }, { "uniprot_ac": "Q12310", "gene_name": "PRR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12310" } ] } ] }, { "uniprot_ac": "Q12469", "gene_name": "SKM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12469" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12469" } ] } ] }, { "uniprot_ac": "Q12505", "gene_name": "SKS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12505" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12505" } ] } ] }, { "uniprot_ac": "Q12851", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q12851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12851" } ] } ] }, { "uniprot_ac": "Q12852", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q12852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12852" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q12852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12852" } ] } ] }, { "uniprot_ac": "Q13043", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13043" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13043" } ] } ] }, { "uniprot_ac": "Q13131", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q13131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13131" } ] } ] }, { "uniprot_ac": "Q13153", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13153" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13153" } ] } ] }, { "uniprot_ac": "Q13163", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13163" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q13163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13163" } ] } ] }, { "uniprot_ac": "Q13164", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13164" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q13164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13164" } ] } ] }, { "uniprot_ac": "Q13177", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13177" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13177" } ] } ] }, { "uniprot_ac": "Q13188", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13188" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13188" } ] } ] }, { "uniprot_ac": "Q13233", "gene_name": "MAP3K1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] }, { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q13233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13233" } ] } ] }, { "uniprot_ac": "Q13237", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13237" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q13237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13237" } ] } ] }, { "uniprot_ac": "Q13315", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13315" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13315" } ] } ] }, { "uniprot_ac": "Q13418", "gene_name": "ILK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13418" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13418" } ] } ] }, { "uniprot_ac": "Q13464", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13464" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13464", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13464" } ] } ] }, { "uniprot_ac": "Q13523", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13523" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13523" } ] } ] }, { "uniprot_ac": "Q13535", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13535" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13535" } ] } ] }, { "uniprot_ac": "Q13546", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13546" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q13546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13546" } ] } ] }, { "uniprot_ac": "Q13554", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13554" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13554" } ] } ] }, { "uniprot_ac": "Q13555", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13555" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13555", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13555" } ] } ] }, { "uniprot_ac": "Q13557", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13557" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q13557", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13557" } ] } ] }, { "uniprot_ac": "Q13627", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q13627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13627" } ] } ] }, { "uniprot_ac": "Q13976", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q13976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13976" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q13976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q13976" } ] } ] }, { "uniprot_ac": "Q14004", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q14004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14004" } ] } ] }, { "uniprot_ac": "Q14012", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14012" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q14012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14012" } ] } ] }, { "uniprot_ac": "Q14296", "gene_name": "FASTK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.8", "activity": "ATP + L-threonyl-[Fas-activated protein] = ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein].", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.8", "activity": "", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q14296", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14296" } ] } ] }, { "uniprot_ac": "Q14680", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q14680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14680" } ] } ] }, { "uniprot_ac": "Q14AX6", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q14AX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q14AX6" } ] } ] }, { "uniprot_ac": "Q15131", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15131" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q15131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15131" } ] } ] }, { "uniprot_ac": "Q15139", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15139" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q15139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15139" } ] } ] }, { "uniprot_ac": "Q15208", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15208" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15208" } ] } ] }, { "uniprot_ac": "Q15349", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15349" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15349" } ] } ] }, { "uniprot_ac": "Q15418", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15418" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15418", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15418" } ] } ] }, { "uniprot_ac": "Q15569", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15569" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q15569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15569" } ] } ] }, { "uniprot_ac": "Q15759", "gene_name": "MAPK11", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15759" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q15759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15759" } ] } ] }, { "uniprot_ac": "Q15772", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15772" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15772" } ] } ] }, { "uniprot_ac": "Q15831", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q15831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15831" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q15831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q15831" } ] } ] }, { "uniprot_ac": "Q16512", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16512" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q16512", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16512" } ] } ] }, { "uniprot_ac": "Q16513", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16513" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q16513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16513" } ] } ] }, { "uniprot_ac": "Q16539", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16539" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16539", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16539" } ] } ] }, { "uniprot_ac": "Q16566", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16566" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q16566", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16566" } ] } ] }, { "uniprot_ac": "Q16584", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16584" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q16584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16584" } ] } ] }, { "uniprot_ac": "Q16644", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q16644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16644" } ] } ] }, { "uniprot_ac": "Q16659", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q16659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16659" } ] } ] }, { "uniprot_ac": "Q16816", "gene_name": "PHKG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "Q16816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q16816" } ] } ] }, { "uniprot_ac": "Q1EG27", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1EG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1EG27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1EG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1EG27" } ] } ] }, { "uniprot_ac": "Q1HKZ5", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1HKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HKZ5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q1HKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HKZ5" } ] } ] }, { "uniprot_ac": "Q1ZXC8", "gene_name": "pXi", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXC8" } ] } ] }, { "uniprot_ac": "Q1ZXD6", "gene_name": "roco5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXD6" } ] } ] }, { "uniprot_ac": "Q1ZXH2", "gene_name": "fhkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXH2" } ] } ] }, { "uniprot_ac": "Q1ZXI5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXI5" } ] } ] }, { "uniprot_ac": "Q1ZXR2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q1ZXR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ZXR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXR2" } ] } ] }, { "uniprot_ac": "Q23915", "gene_name": "kinX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q23915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23915" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q23915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23915" } ] } ] }, { "uniprot_ac": "Q23977", "gene_name": "hep", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23977" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q23977" } ] } ] }, { "uniprot_ac": "Q24210", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24210" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24210" } ] } ] }, { "uniprot_ac": "Q24324", "gene_name": "Dsor1", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24324" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q24324" } ] } ] }, { "uniprot_ac": "Q2M2I8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q2M2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2M2I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2M2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2M2I8" } ] } ] }, { "uniprot_ac": "Q2NL51", "gene_name": "Gsk3a", "activity": [ { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q2NL51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q2NL51" } ] } ] }, { "uniprot_ac": "Q38SD2", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q38SD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q38SD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q38SD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q38SD2" } ] } ] }, { "uniprot_ac": "Q3MJK5", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q3MJK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MJK5" } ] } ] }, { "uniprot_ac": "Q3TYD6", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3TYD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TYD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3TYD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TYD6" } ] } ] }, { "uniprot_ac": "Q3TZA2", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3TZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TZA2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3TZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TZA2" } ] } ] }, { "uniprot_ac": "Q3U1V8", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U1V8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q3U1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U1V8" } ] } ] }, { "uniprot_ac": "Q3U214", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U214" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3U214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U214" } ] } ] }, { "uniprot_ac": "Q3U3Q1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3U3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U3Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3U3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U3Q1" } ] } ] }, { "uniprot_ac": "Q3UGM2", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UGM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UGM2" } ] } ] }, { "uniprot_ac": "Q3UH66", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UH66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UH66" } ] } ] }, { "uniprot_ac": "Q3UHC2", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHC2" } ] } ] }, { "uniprot_ac": "Q3UHJ0", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UHJ0" } ] } ] }, { "uniprot_ac": "Q3ULB5", "gene_name": "Pak6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3ULB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3ULB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3ULB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3ULB5" } ] } ] }, { "uniprot_ac": "Q3UMM4", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMM4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3UMM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMM4" } ] } ] }, { "uniprot_ac": "Q3UMW7", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMW7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UMW7" } ] } ] }, { "uniprot_ac": "Q3UT86", "gene_name": "Gm5891", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UT86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UT86" } ] } ] }, { "uniprot_ac": "Q3UTA8", "gene_name": "Gm4567", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UTA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UTA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTA8" } ] } ] }, { "uniprot_ac": "Q3UTQ8", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UTQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3UTQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UTQ8" } ] } ] }, { "uniprot_ac": "Q3UU96", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UU96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UU96" } ] } ] }, { "uniprot_ac": "Q3UVC0", "gene_name": "Ksr2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVC0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UVC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVC0" } ] } ] }, { "uniprot_ac": "Q3UVR3", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3UVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVR3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3UVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UVR3" } ] } ] }, { "uniprot_ac": "Q3V016", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V016" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3V016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V016" } ] } ] }, { "uniprot_ac": "Q3V129", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V129" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3V129", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V129" } ] } ] }, { "uniprot_ac": "Q3V3A1", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q3V3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V3A1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q3V3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3V3A1" } ] } ] }, { "uniprot_ac": "Q4FZD7", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4FZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4FZD7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q4FZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4FZD7" } ] } ] }, { "uniprot_ac": "Q4G050", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4G050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G050" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4G050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G050" } ] } ] }, { "uniprot_ac": "Q4KLN3", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KLN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4KLN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KLN3" } ] } ] }, { "uniprot_ac": "Q4KM34", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KM34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM34" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q4KM34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM34" } ] } ] }, { "uniprot_ac": "Q4KM47", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM47" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q4KM47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KM47" } ] } ] }, { "uniprot_ac": "Q4KSH6", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q4KSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH6" } ] } ] }, { "uniprot_ac": "Q4KSH7", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4KSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q4KSH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4KSH7" } ] } ] }, { "uniprot_ac": "Q4V793", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4V793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q4V793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V793" } ] } ] }, { "uniprot_ac": "Q4V8A3", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q4V8A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V8A3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4V8A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4V8A3" } ] } ] }, { "uniprot_ac": "Q52WX2", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q52WX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q52WX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q52WX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q52WX2" } ] } ] }, { "uniprot_ac": "Q53UA7", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q53UA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q53UA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q53UA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q53UA7" } ] } ] }, { "uniprot_ac": "Q54B33", "gene_name": "pakE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54B33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54B33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B33" } ] } ] }, { "uniprot_ac": "Q54B48", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54B48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B48" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54B48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B48" } ] } ] }, { "uniprot_ac": "Q54BC9", "gene_name": "dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54BC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BC9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q54BC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BC9" } ] } ] }, { "uniprot_ac": "Q54BF0", "gene_name": "fhkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54BF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54BF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54BF0" } ] } ] }, { "uniprot_ac": "Q54C18", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54C18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54C18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C18" } ] } ] }, { "uniprot_ac": "Q54C38", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54C38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54C38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C38" } ] } ] }, { "uniprot_ac": "Q54C71", "gene_name": "kxcB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54C71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54C71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54C71" } ] } ] }, { "uniprot_ac": "Q54D75", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54D75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54D75" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q54D75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54D75" } ] } ] }, { "uniprot_ac": "Q54DC8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DC8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DC8" } ] } ] }, { "uniprot_ac": "Q54DF2", "gene_name": "mrkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DF2" } ] } ] }, { "uniprot_ac": "Q54DK3", "gene_name": "cdc7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DK3" } ] } ] }, { "uniprot_ac": "Q54DY0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54DY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54DY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54DY0" } ] } ] }, { "uniprot_ac": "Q54E34", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54E34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54E34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54E34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54E34" } ] } ] }, { "uniprot_ac": "Q54EG9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54EG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54EG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EG9" } ] } ] }, { "uniprot_ac": "Q54EM1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54EM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54EM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EM1" } ] } ] }, { "uniprot_ac": "Q54ER4", "gene_name": "atr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54ER4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ER4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54ER4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ER4" } ] } ] }, { "uniprot_ac": "Q54ET3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54ET3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ET3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54ET3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ET3" } ] } ] }, { "uniprot_ac": "Q54EY4", "gene_name": "dst3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54EY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54EY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54EY4" } ] } ] }, { "uniprot_ac": "Q54F40", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54F40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54F40" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54F40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54F40" } ] } ] }, { "uniprot_ac": "Q54FH3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54FH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54FH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54FH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54FH3" } ] } ] }, { "uniprot_ac": "Q54FR9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54FR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54FR9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54FR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54FR9" } ] } ] }, { "uniprot_ac": "Q54G43", "gene_name": "shkE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54G43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54G43" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54G43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54G43" } ] } ] }, { "uniprot_ac": "Q54GY6", "gene_name": "kxcA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54GY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54GY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54GY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54GY6" } ] } ] }, { "uniprot_ac": "Q54H05", "gene_name": "kinY", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54H05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54H05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54H05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54H05" } ] } ] }, { "uniprot_ac": "Q54H45", "gene_name": "drkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54H45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54H45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54H45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54H45" } ] } ] }, { "uniprot_ac": "Q54H46", "gene_name": "drkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54H46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54H46" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54H46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54H46" } ] } ] }, { "uniprot_ac": "Q54HC6", "gene_name": "arkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54HC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54HC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HC6" } ] } ] }, { "uniprot_ac": "Q54HD2", "gene_name": "ndrD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54HD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54HD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HD2" } ] } ] }, { "uniprot_ac": "Q54HS0", "gene_name": "nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54HS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54HS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54HS0" } ] } ] }, { "uniprot_ac": "Q54I36", "gene_name": "pyk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54I36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54I36" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q54I36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54I36" } ] } ] }, { "uniprot_ac": "Q54IE8", "gene_name": "irlE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54IE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54IE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IE8" } ] } ] }, { "uniprot_ac": "Q54IF2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54IF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54IF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IF2" } ] } ] }, { "uniprot_ac": "Q54IH8", "gene_name": "ndrB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54IH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54IH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IH8" } ] } ] }, { "uniprot_ac": "Q54IP4", "gene_name": "shkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54IP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54IP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54IP4" } ] } ] }, { "uniprot_ac": "Q54JC7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54JC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54JC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54JC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54JC7" } ] } ] }, { "uniprot_ac": "Q54JG7", "gene_name": "dst4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54JG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54JG7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54JG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54JG7" } ] } ] }, { "uniprot_ac": "Q54JQ1", "gene_name": "mkcC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54JQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54JQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54JQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54JQ1" } ] } ] }, { "uniprot_ac": "Q54L00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54L00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54L00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54L00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54L00" } ] } ] }, { "uniprot_ac": "Q54L81", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54L81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54L81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54L81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54L81" } ] } ] }, { "uniprot_ac": "Q54LH8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54LH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54LH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54LH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54LH8" } ] } ] }, { "uniprot_ac": "Q54LR6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54LR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54LR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54LR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54LR6" } ] } ] }, { "uniprot_ac": "Q54LU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54LU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54LU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54LU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54LU8" } ] } ] }, { "uniprot_ac": "Q54M77", "gene_name": "roco8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54M77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54M77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54M77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54M77" } ] } ] }, { "uniprot_ac": "Q54MH0", "gene_name": "fhkD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54MH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54MH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MH0" } ] } ] }, { "uniprot_ac": "Q54MV2", "gene_name": "mrkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54MV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54MV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MV2" } ] } ] }, { "uniprot_ac": "Q54MY9", "gene_name": "mkcA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54MY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54MY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54MY9" } ] } ] }, { "uniprot_ac": "Q54P26", "gene_name": "samkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54P26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54P26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P26" } ] } ] }, { "uniprot_ac": "Q54P47", "gene_name": "ndrC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54P47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54P47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54P47" } ] } ] }, { "uniprot_ac": "Q54PK8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK8" } ] } ] }, { "uniprot_ac": "Q54PK9", "gene_name": "pdkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PK9" } ] } ] }, { "uniprot_ac": "Q54PX0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54PX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PX0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54PX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54PX0" } ] } ] }, { "uniprot_ac": "Q54Q69", "gene_name": "dhkG", "activity": [ { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "Q54Q69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Q69" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54Q69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Q69" } ] } ] }, { "uniprot_ac": "Q54QB1", "gene_name": "erkB", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QB1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q54QB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QB1" } ] } ] }, { "uniprot_ac": "Q54QD5", "gene_name": "nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QD5" } ] } ] }, { "uniprot_ac": "Q54QI2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QI2" } ] } ] }, { "uniprot_ac": "Q54QQ1", "gene_name": "phg2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54QQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QQ1" } ] } ] }, { "uniprot_ac": "Q54QV3", "gene_name": "yakA", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54QV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QV3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q54QV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54QV3" } ] } ] }, { "uniprot_ac": "Q54R82", "gene_name": "mkkA", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54R82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R82" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q54R82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R82" } ] } ] }, { "uniprot_ac": "Q54R95", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54R95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54R95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R95" } ] } ] }, { "uniprot_ac": "Q54R98", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54R98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54R98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54R98" } ] } ] }, { "uniprot_ac": "Q54RB2", "gene_name": "cdk11", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q54RB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RB2" } ] } ] }, { "uniprot_ac": "Q54RB7", "gene_name": "shkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RB7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RB7" } ] } ] }, { "uniprot_ac": "Q54RJ4", "gene_name": "iksA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RJ4" } ] } ] }, { "uniprot_ac": "Q54RP7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RP7" } ] } ] }, { "uniprot_ac": "Q54RR9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RR9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RR9" } ] } ] }, { "uniprot_ac": "Q54RV3", "gene_name": "pakG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RV3" } ] } ] }, { "uniprot_ac": "Q54RZ7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54RZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54RZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RZ7" } ] } ] }, { "uniprot_ac": "Q54S77", "gene_name": "vps15", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54S77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54S77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54S77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54S77" } ] } ] }, { "uniprot_ac": "Q54SC4", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54SC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54SC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54SC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54SC4" } ] } ] }, { "uniprot_ac": "Q54SK3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54SK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54SK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54SK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54SK3" } ] } ] }, { "uniprot_ac": "Q54T05", "gene_name": "rio2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54T05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54T05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54T05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54T05" } ] } ] }, { "uniprot_ac": "Q54TA1", "gene_name": "drkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54TA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54TA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TA1" } ] } ] }, { "uniprot_ac": "Q54TA3", "gene_name": "mrkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54TA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54TA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TA3" } ] } ] }, { "uniprot_ac": "Q54TH6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54TH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54TH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TH6" } ] } ] }, { "uniprot_ac": "Q54TM7", "gene_name": "drkD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54TM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TM7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54TM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TM7" } ] } ] }, { "uniprot_ac": "Q54TN4", "gene_name": "mkcE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54TN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54TN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TN4" } ] } ] }, { "uniprot_ac": "Q54TW2", "gene_name": "pdkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54TW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54TW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54TW2" } ] } ] }, { "uniprot_ac": "Q54U31", "gene_name": "shkD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54U31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54U31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54U31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54U31" } ] } ] }, { "uniprot_ac": "Q54U65", "gene_name": "7tmk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54U65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54U65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54U65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54U65" } ] } ] }, { "uniprot_ac": "Q54UA9", "gene_name": "clkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54UA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54UA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UA9" } ] } ] }, { "uniprot_ac": "Q54UC0", "gene_name": "dnapkcs", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54UC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UC0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54UC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UC0" } ] } ] }, { "uniprot_ac": "Q54UL8", "gene_name": "mps1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54UL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UL8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54UL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UL8" } ] } ] }, { "uniprot_ac": "Q54UZ1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54UZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54UZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54UZ1" } ] } ] }, { "uniprot_ac": "Q54V35", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54V35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54V35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54V35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54V35" } ] } ] }, { "uniprot_ac": "Q54V83", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54V83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54V83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54V83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54V83" } ] } ] }, { "uniprot_ac": "Q54VC0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54VC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VC0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54VC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VC0" } ] } ] }, { "uniprot_ac": "Q54VD8", "gene_name": "rio1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54VD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VD8" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q54VD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VD8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54VD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VD8" } ] } ] }, { "uniprot_ac": "Q54VI1", "gene_name": "fhkE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54VI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54VI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VI1" } ] } ] }, { "uniprot_ac": "Q54VU4", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54VU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VU4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54VU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VU4" } ] } ] }, { "uniprot_ac": "Q54VV7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54VV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54VV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54VV7" } ] } ] }, { "uniprot_ac": "Q54W07", "gene_name": "bud32", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54W07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54W07" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q54W07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54W07" } ] } ] }, { "uniprot_ac": "Q54WC0", "gene_name": "STK19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WC0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WC0" } ] } ] }, { "uniprot_ac": "Q54WD7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WD7" } ] } ] }, { "uniprot_ac": "Q54WE5", "gene_name": "prpf4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WE5" } ] } ] }, { "uniprot_ac": "Q54WJ0", "gene_name": "lkb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WJ0" } ] } ] }, { "uniprot_ac": "Q54WS5", "gene_name": "roco6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WS5" } ] } ] }, { "uniprot_ac": "Q54WW7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WW7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WW7" } ] } ] }, { "uniprot_ac": "Q54WX4", "gene_name": "aurK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54WX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54WX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54WX4" } ] } ] }, { "uniprot_ac": "Q54XJ4", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54XJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54XJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XJ4" } ] } ] }, { "uniprot_ac": "Q54XL6", "gene_name": "fray1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54XL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54XL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XL6" } ] } ] }, { "uniprot_ac": "Q54XQ2", "gene_name": "rckA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XQ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54XQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XQ2" } ] } ] }, { "uniprot_ac": "Q54XX5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54XX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XX5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54XX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XX5" } ] } ] }, { "uniprot_ac": "Q54XY6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54XY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54XY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XY6" } ] } ] }, { "uniprot_ac": "Q54XZ5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54XZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54XZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54XZ5" } ] } ] }, { "uniprot_ac": "Q54Y06", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54Y06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q54Y06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y06" } ] } ] }, { "uniprot_ac": "Q54Y26", "gene_name": "ndrA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54Y26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54Y26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y26" } ] } ] }, { "uniprot_ac": "Q54Y55", "gene_name": "shkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54Y55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54Y55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y55" } ] } ] }, { "uniprot_ac": "Q54Y90", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54Y90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54Y90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54Y90" } ] } ] }, { "uniprot_ac": "Q54YF2", "gene_name": "snfA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54YF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54YF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54YF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54YF2" } ] } ] }, { "uniprot_ac": "Q54YZ5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54YZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54YZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54YZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54YZ5" } ] } ] }, { "uniprot_ac": "Q54ZN3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q54ZN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ZN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q54ZN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54ZN3" } ] } ] }, { "uniprot_ac": "Q550K8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q550K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q550K8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q550K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q550K8" } ] } ] }, { "uniprot_ac": "Q550L8", "gene_name": "ifkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q550L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q550L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q550L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q550L8" } ] } ] }, { "uniprot_ac": "Q551H4", "gene_name": "fray2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q551H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q551H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q551H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q551H4" } ] } ] }, { "uniprot_ac": "Q552C1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q552C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q552C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552C1" } ] } ] }, { "uniprot_ac": "Q552C6", "gene_name": "zak2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q552C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552C6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q552C6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552C6" } ] } ] }, { "uniprot_ac": "Q552E9", "gene_name": "pkgA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q552E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q552E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552E9" } ] } ] }, { "uniprot_ac": "Q552Z2", "gene_name": "fnkE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q552Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552Z2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q552Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q552Z2" } ] } ] }, { "uniprot_ac": "Q553E9", "gene_name": "smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q553E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q553E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q553E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q553E9" } ] } ] }, { "uniprot_ac": "Q556J6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q556J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556J6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q556J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556J6" } ] } ] }, { "uniprot_ac": "Q556Q3", "gene_name": "irlF-2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q556Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q556Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Q3" } ] } ] }, { "uniprot_ac": "Q556S2", "gene_name": "pakH-2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q556S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556S2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q556S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556S2" } ] } ] }, { "uniprot_ac": "Q556Y4", "gene_name": "cak1-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q556Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Y4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q556Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q556Y4" } ] } ] }, { "uniprot_ac": "Q557G1", "gene_name": "irlB-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q557G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q557G1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q557G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q557G1" } ] } ] }, { "uniprot_ac": "Q558U1", "gene_name": "ifkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q558U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q558U1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q558U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q558U1" } ] } ] }, { "uniprot_ac": "Q559A2", "gene_name": "irlA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q559A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q559A2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q559A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q559A2" } ] } ] }, { "uniprot_ac": "Q559T8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q559T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q559T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q559T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q559T8" } ] } ] }, { "uniprot_ac": "Q55A09", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55A09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55A09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55A09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55A09" } ] } ] }, { "uniprot_ac": "Q55A55", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55A55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55A55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55A55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55A55" } ] } ] }, { "uniprot_ac": "Q55BA0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55BA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BA0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55BA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BA0" } ] } ] }, { "uniprot_ac": "Q55BN8", "gene_name": "nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55BN8" } ] } ] }, { "uniprot_ac": "Q55CA6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55CA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CA6" } ] } ] }, { "uniprot_ac": "Q55CE0", "gene_name": "mkcF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CE0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55CE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CE0" } ] } ] }, { "uniprot_ac": "Q55CL6", "gene_name": "mekA", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CL6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q55CL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CL6" } ] } ] }, { "uniprot_ac": "Q55CW2", "gene_name": "samkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55CW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CW2" } ] } ] }, { "uniprot_ac": "Q55CW3", "gene_name": "samkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55CW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CW3" } ] } ] }, { "uniprot_ac": "Q55CY9", "gene_name": "gdt8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55CY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CY9" } ] } ] }, { "uniprot_ac": "Q55CZ1", "gene_name": "gdt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55CZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55CZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55CZ1" } ] } ] }, { "uniprot_ac": "Q55D99", "gene_name": "pakA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55D99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55D99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55D99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55D99" } ] } ] }, { "uniprot_ac": "Q55DD4", "gene_name": "pakD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55DD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DD4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55DD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DD4" } ] } ] }, { "uniprot_ac": "Q55DJ8", "gene_name": "irlC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55DJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55DJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DJ8" } ] } ] }, { "uniprot_ac": "Q55DJ9", "gene_name": "irlD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55DJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55DJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DJ9" } ] } ] }, { "uniprot_ac": "Q55DK2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55DK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55DK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DK2" } ] } ] }, { "uniprot_ac": "Q55DU7", "gene_name": "gdt4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55DU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55DU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55DU7" } ] } ] }, { "uniprot_ac": "Q55E58", "gene_name": "pats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55E58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55E58" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55E58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55E58" } ] } ] }, { "uniprot_ac": "Q55EC7", "gene_name": "gefX", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55EC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55EC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55EC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55EC7" } ] } ] }, { "uniprot_ac": "Q55EI8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55EI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55EI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55EI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55EI8" } ] } ] }, { "uniprot_ac": "Q55F45", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55F45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55F45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55F45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55F45" } ] } ] }, { "uniprot_ac": "Q55FJ6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FJ6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q55FJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FJ6" } ] } ] }, { "uniprot_ac": "Q55FS2", "gene_name": "krsB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FS2" } ] } ] }, { "uniprot_ac": "Q55FT4", "gene_name": "tsuA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FT4" } ] } ] }, { "uniprot_ac": "Q55FV4", "gene_name": "fnkB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV4" } ] } ] }, { "uniprot_ac": "Q55FV5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55FV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55FV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55FV5" } ] } ] }, { "uniprot_ac": "Q55GC2", "gene_name": "dst2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GC2" } ] } ] }, { "uniprot_ac": "Q55GE6", "gene_name": "roco7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GE6" } ] } ] }, { "uniprot_ac": "Q55GG4", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GG4" } ] } ] }, { "uniprot_ac": "Q55GJ2", "gene_name": "ireA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GJ2" } ] } ] }, { "uniprot_ac": "Q55GS4", "gene_name": "cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GS4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q55GS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GS4" } ] } ] }, { "uniprot_ac": "Q55GU0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GU0" } ] } ] }, { "uniprot_ac": "Q55GV3", "gene_name": "pakC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q55GV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q55GV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55GV3" } ] } ] }, { "uniprot_ac": "Q56UN5", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q56UN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q56UN5" } ] } ] }, { "uniprot_ac": "Q59H18", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q59H18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q59H18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q59H18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q59H18" } ] } ] }, { "uniprot_ac": "Q5EAK6", "gene_name": "tefu", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EAK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EAK6" } ] } ] }, { "uniprot_ac": "Q5EG47", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q5EG47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5EG47" } ] } ] }, { "uniprot_ac": "Q5F2E8", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5F2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F2E8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F2E8" } ] } ] }, { "uniprot_ac": "Q5GIG6", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5GIG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5GIG6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5GIG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5GIG6" } ] } ] }, { "uniprot_ac": "Q5MAI5", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MAI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MAI5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5MAI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MAI5" } ] } ] }, { "uniprot_ac": "Q5MJS3", "gene_name": "Fam20c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MJS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5MJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MJS3" } ] } ] }, { "uniprot_ac": "Q5MPA9", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5MPA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MPA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5MPA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5MPA9" } ] } ] }, { "uniprot_ac": "Q5PQT0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5PQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5PQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5PQT0" } ] } ] }, { "uniprot_ac": "Q5RJI5", "gene_name": "Brsk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q5RJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RJI5" } ] } ] }, { "uniprot_ac": "Q5RKH1", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5RKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKH1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5RKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKH1" } ] } ] }, { "uniprot_ac": "Q5S006", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S006" } ] }, { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S006" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5S006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S006" } ] } ] }, { "uniprot_ac": "Q5S007", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5S007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S007" } ] }, { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5S007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S007" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5S007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5S007" } ] } ] }, { "uniprot_ac": "Q5SUV5", "gene_name": "Mylk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5SUV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SUV5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SUV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SUV5" } ] } ] }, { "uniprot_ac": "Q5SYL1", "gene_name": "Rskr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5SYL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SYL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SYL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5SYL1" } ] } ] }, { "uniprot_ac": "Q5TCX8", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5TCX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCX8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q5TCX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCX8" } ] } ] }, { "uniprot_ac": "Q5TCY1", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5TCY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5TCY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5TCY1" } ] } ] }, { "uniprot_ac": "Q5U2N4", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U2N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U2N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2N4" } ] } ] }, { "uniprot_ac": "Q5U2X5", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U2X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U2X5" } ] } ] }, { "uniprot_ac": "Q5U452", "gene_name": "Trp53rka", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U452" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5U452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U452" } ] } ] }, { "uniprot_ac": "Q5U4C9", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5U4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U4C9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5U4C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5U4C9" } ] } ] }, { "uniprot_ac": "Q5VJL3", "gene_name": "gdt9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VJL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VJL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VJL3" } ] } ] }, { "uniprot_ac": "Q5VST9", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VST9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VST9" } ] } ] }, { "uniprot_ac": "Q5VT25", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5VT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VT25" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5VT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5VT25" } ] } ] }, { "uniprot_ac": "Q5XIS9", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q5XIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIS9" } ] } ] }, { "uniprot_ac": "Q5XIT0", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIT0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XIT0" } ] } ] }, { "uniprot_ac": "Q5XJV6", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5XJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5XJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5XJV6" } ] } ] }, { "uniprot_ac": "Q60592", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60592" } ] } ] }, { "uniprot_ac": "Q60670", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60670" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60670" } ] } ] }, { "uniprot_ac": "Q60700", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60700" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q60700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60700" } ] } ] }, { "uniprot_ac": "Q60737", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60737" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60737", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60737" } ] } ] }, { "uniprot_ac": "Q60806", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60806" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q60806", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60806" } ] } ] }, { "uniprot_ac": "Q60823", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60823" } ] } ] }, { "uniprot_ac": "Q60855", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q60855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60855" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q60855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q60855" } ] } ] }, { "uniprot_ac": "Q61036", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61036", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61036" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61036", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61036" } ] } ] }, { "uniprot_ac": "Q61083", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61083" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q61083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61083" } ] } ] }, { "uniprot_ac": "Q61084", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61084" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q61084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61084" } ] } ] }, { "uniprot_ac": "Q61097", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61097" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61097" } ] } ] }, { "uniprot_ac": "Q61136", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] } ] }, { "uniprot_ac": "Q61161", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61161" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61161" } ] } ] }, { "uniprot_ac": "Q61214", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q61214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61214" } ] } ] }, { "uniprot_ac": "Q61241", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61241" } ] } ] }, { "uniprot_ac": "Q61410", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61410" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q61410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61410" } ] } ] }, { "uniprot_ac": "Q61532", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61532" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q61532", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61532" } ] } ] }, { "uniprot_ac": "Q61831", "gene_name": "Mapk10", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61831" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q61831", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61831" } ] } ] }, { "uniprot_ac": "Q61846", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] }, { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q61846", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61846" } ] } ] }, { "uniprot_ac": "Q62070", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62070" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62070", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62070" } ] } ] }, { "uniprot_ac": "Q62073", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62073" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q62073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62073" } ] } ] }, { "uniprot_ac": "Q62074", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62074" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q62074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62074" } ] } ] }, { "uniprot_ac": "Q62101", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62101" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q62101", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62101" } ] } ] }, { "uniprot_ac": "Q62388", "gene_name": "Atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62388" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62388" } ] } ] }, { "uniprot_ac": "Q62406", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62406" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62406" } ] } ] }, { "uniprot_ac": "Q62407", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62407" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62407" } ] } ] }, { "uniprot_ac": "Q62673", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62673" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q62673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62673" } ] } ] }, { "uniprot_ac": "Q62726", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62726" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62726" } ] } ] }, { "uniprot_ac": "Q62761", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62761" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62761" } ] } ] }, { "uniprot_ac": "Q62762", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62762" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62762" } ] } ] }, { "uniprot_ac": "Q62763", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62763" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62763", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62763" } ] } ] }, { "uniprot_ac": "Q62829", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62829" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62829" } ] } ] }, { "uniprot_ac": "Q62862", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62862" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q62862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62862" } ] } ] }, { "uniprot_ac": "Q62868", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62868" } ] } ] }, { "uniprot_ac": "Q62915", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62915" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q62915", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62915" } ] } ] }, { "uniprot_ac": "Q62925", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q62925", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62925" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q62925", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q62925" } ] } ] }, { "uniprot_ac": "Q63117", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63117" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63117" } ] } ] }, { "uniprot_ac": "Q63184", "gene_name": "Eif2ak2", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63184" } ] } ] }, { "uniprot_ac": "Q63185", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63185" } ] } ] }, { "uniprot_ac": "Q63285", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63285" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63285", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63285" } ] } ] }, { "uniprot_ac": "Q63433", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63433" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q63433", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63433" } ] } ] }, { "uniprot_ac": "Q63450", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63450" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q63450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63450" } ] } ] }, { "uniprot_ac": "Q63454", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63454" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63454" } ] } ] }, { "uniprot_ac": "Q63470", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] }, { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63470", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63470" } ] } ] }, { "uniprot_ac": "Q63484", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63484" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63484" } ] } ] }, { "uniprot_ac": "Q63531", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63531" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63531" } ] } ] }, { "uniprot_ac": "Q63538", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63538" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63538" } ] } ] }, { "uniprot_ac": "Q63553", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63553" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63553", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63553" } ] } ] }, { "uniprot_ac": "Q63562", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63562" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q63562", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63562" } ] } ] }, { "uniprot_ac": "Q63572", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63572" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q63572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63572" } ] } ] }, { "uniprot_ac": "Q63638", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63638" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63638", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63638" } ] } ] }, { "uniprot_ac": "Q63644", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63644" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q63644", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63644" } ] } ] }, { "uniprot_ac": "Q63686", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63686" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q63686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63686" } ] } ] }, { "uniprot_ac": "Q63699", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63699" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q63699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63699" } ] } ] }, { "uniprot_ac": "Q63796", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63796" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q63796", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63796" } ] } ] }, { "uniprot_ac": "Q63844", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63844" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q63844", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63844" } ] } ] }, { "uniprot_ac": "Q63932", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63932" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q63932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63932" } ] } ] }, { "uniprot_ac": "Q63945", "gene_name": "Set", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q63945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63945" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q63945", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q63945" } ] } ] }, { "uniprot_ac": "Q641K5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q641K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641K5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q641K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641K5" } ] } ] }, { "uniprot_ac": "Q641Z4", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q641Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q641Z4" } ] } ] }, { "uniprot_ac": "Q64261", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64261" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q64261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64261" } ] } ] }, { "uniprot_ac": "Q64303", "gene_name": "Pak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64303" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q64303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64303" } ] } ] }, { "uniprot_ac": "Q64595", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64595" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q64595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64595" } ] } ] }, { "uniprot_ac": "Q64617", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64617" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q64617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64617" } ] } ] }, { "uniprot_ac": "Q64702", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q64702", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64702" } ] } ] }, { "uniprot_ac": "Q66H84", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66H84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q66H84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66H84" } ] } ] }, { "uniprot_ac": "Q66HA1", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HA1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q66HA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HA1" } ] } ] }, { "uniprot_ac": "Q66HE5", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q66HE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE5" } ] } ] }, { "uniprot_ac": "Q66HE7", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66HE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q66HE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66HE7" } ] } ] }, { "uniprot_ac": "Q66L42", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q66L42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66L42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q66L42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q66L42" } ] } ] }, { "uniprot_ac": "Q69Z98", "gene_name": "Brsk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q69Z98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69Z98" } ] } ] }, { "uniprot_ac": "Q69ZA1", "gene_name": "Cdk13", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q69ZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZA1" } ] } ] }, { "uniprot_ac": "Q69ZM6", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q69ZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q69ZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q69ZM6" } ] } ] }, { "uniprot_ac": "Q6A1A2", "gene_name": "PDPK2P", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6A1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6A1A2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6A1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6A1A2" } ] } ] }, { "uniprot_ac": "Q6B9X6", "gene_name": "vwkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6B9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B9X6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6B9X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6B9X6" } ] } ] }, { "uniprot_ac": "Q6DT37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6DT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DT37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6DT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DT37" } ] } ] }, { "uniprot_ac": "Q6IQ55", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6IQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6IQ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6IQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6IQ55" } ] } ] }, { "uniprot_ac": "Q6P0Q8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P0Q8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P0Q8" } ] } ] }, { "uniprot_ac": "Q6P2M8", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P2M8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q6P2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P2M8" } ] } ] }, { "uniprot_ac": "Q6P3R8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P3R8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P3R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P3R8" } ] } ] }, { "uniprot_ac": "Q6P4S6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P4S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4S6" } ] } ] }, { "uniprot_ac": "Q6P5G0", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5G0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q6P5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5G0" } ] } ] }, { "uniprot_ac": "Q6P5Z2", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P5Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5Z2" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q6P5Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P5Z2" } ] } ] }, { "uniprot_ac": "Q6P9R2", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6P9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P9R2" } ] } ] }, { "uniprot_ac": "Q6PAJ1", "gene_name": "Bcr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PAJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PAJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PAJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PAJ1" } ] } ] }, { "uniprot_ac": "Q6PCN3", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PCN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PCN3" } ] } ] }, { "uniprot_ac": "Q6PGN3", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PGN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PGN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PGN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PGN3" } ] } ] }, { "uniprot_ac": "Q6PHR2", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHR2" } ] } ] }, { "uniprot_ac": "Q6PHZ2", "gene_name": "Camk2d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6PHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHZ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q6PHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6PHZ2" } ] } ] }, { "uniprot_ac": "Q6SA08", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6SA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6SA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6SA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6SA08" } ] } ] }, { "uniprot_ac": "Q6V9V9", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9V9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9V9" } ] } ] }, { "uniprot_ac": "Q6V9Y2", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y2" } ] } ] }, { "uniprot_ac": "Q6V9Y3", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6V9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6V9Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6V9Y3" } ] } ] }, { "uniprot_ac": "Q6VAB6", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6VAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6VAB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6VAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6VAB6" } ] } ] }, { "uniprot_ac": "Q6XHA5", "gene_name": "roco11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XHA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6XHA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA5" } ] } ] }, { "uniprot_ac": "Q6XHA7", "gene_name": "roco9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XHA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6XHA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHA7" } ] } ] }, { "uniprot_ac": "Q6XHB2", "gene_name": "roco4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XHB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6XHB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XHB2" } ] } ] }, { "uniprot_ac": "Q6XUX1", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX1" } ] } ] }, { "uniprot_ac": "Q6XUX2", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX2" } ] } ] }, { "uniprot_ac": "Q6XUX3", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6XUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6XUX3" } ] } ] }, { "uniprot_ac": "Q6ZMQ8", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZMQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZMQ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZMQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZMQ8" } ] } ] }, { "uniprot_ac": "Q6ZN16", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZN16" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q6ZN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZN16" } ] } ] }, { "uniprot_ac": "Q6ZQ29", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZQ29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZQ29" } ] } ] }, { "uniprot_ac": "Q6ZWH5", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q6ZWH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZWH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6ZWH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6ZWH5" } ] } ] }, { "uniprot_ac": "Q70PP2", "gene_name": "nonC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q70PP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q70PP2" } ] } ] }, { "uniprot_ac": "Q75JK0", "gene_name": "zakA", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q75JK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JK0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q75JK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JK0" } ] } ] }, { "uniprot_ac": "Q75JN1", "gene_name": "ifkC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q75JN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q75JN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q75JN1" } ] } ] }, { "uniprot_ac": "Q76MJ5", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q76MJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76MJ5" } ] } ] }, { "uniprot_ac": "Q76NV1", "gene_name": "dyrk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76NV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76NV1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q76NV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76NV1" } ] } ] }, { "uniprot_ac": "Q76P07", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q76P07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76P07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q76P07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q76P07" } ] } ] }, { "uniprot_ac": "Q7KRY6", "gene_name": "ball", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KRY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KRY6" } ] } ] }, { "uniprot_ac": "Q7KZI7", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q7KZI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7KZI7" } ] } ] }, { "uniprot_ac": "Q7L7X3", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7L7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L7X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7L7X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7L7X3" } ] } ] }, { "uniprot_ac": "Q7PLI7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7PLI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7PLI7" } ] } ] }, { "uniprot_ac": "Q7TNJ7", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNJ7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q7TNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNJ7" } ] } ] }, { "uniprot_ac": "Q7TNL3", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL3" } ] } ] }, { "uniprot_ac": "Q7TNL4", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TNL4" } ] } ] }, { "uniprot_ac": "Q7TPK6", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TPK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TPK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPK6" } ] } ] }, { "uniprot_ac": "Q7TPS0", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TPS0" } ] } ] }, { "uniprot_ac": "Q7TQP6", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TQP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TQP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TQP6" } ] } ] }, { "uniprot_ac": "Q7TSC3", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSC3" } ] } ] }, { "uniprot_ac": "Q7TSE6", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSE6" } ] } ] }, { "uniprot_ac": "Q7TSJ6", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TSJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TSJ6" } ] } ] }, { "uniprot_ac": "Q7TT49", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TT49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT49" } ] } ] }, { "uniprot_ac": "Q7TT50", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7TT50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT50" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7TT50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7TT50" } ] } ] }, { "uniprot_ac": "Q7Z2Y5", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q7Z2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7Z2Y5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7Z2Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7Z2Y5" } ] } ] }, { "uniprot_ac": "Q80TR8", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80TR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80TR8" } ] } ] }, { "uniprot_ac": "Q80UE6", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UE6" } ] } ] }, { "uniprot_ac": "Q80UV9", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.3.1.48", "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "Q80UV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UV9" } ] } ] }, { "uniprot_ac": "Q80UW5", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80UW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80UW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80UW5" } ] } ] }, { "uniprot_ac": "Q80X41", "gene_name": "Vrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80X41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80X41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80X41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80X41" } ] } ] }, { "uniprot_ac": "Q80XI6", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80XI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XI6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q80XI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XI6" } ] } ] }, { "uniprot_ac": "Q80XP9", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80XP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80XP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80XP9" } ] } ] }, { "uniprot_ac": "Q80Y86", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Y86" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q80Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80Y86" } ] } ] }, { "uniprot_ac": "Q80YE4", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80YE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE4" } ] } ] }, { "uniprot_ac": "Q80YE7", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q80YE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YE7" } ] } ] }, { "uniprot_ac": "Q80YP0", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80YP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YP0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q80YP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80YP0" } ] } ] }, { "uniprot_ac": "Q80ZW0", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q80ZW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80ZW0" } ] } ] }, { "uniprot_ac": "Q810W7", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q810W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810W7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q810W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810W7" } ] } ] }, { "uniprot_ac": "Q811L6", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q811L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q811L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q811L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q811L6" } ] } ] }, { "uniprot_ac": "Q869L4", "gene_name": "fnkA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869L4" } ] } ] }, { "uniprot_ac": "Q869N2", "gene_name": "pakB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869N2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869N2" } ] } ] }, { "uniprot_ac": "Q869T7", "gene_name": "pakF", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869T7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869T7" } ] } ] }, { "uniprot_ac": "Q869X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q869X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q869X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q869X3" } ] } ] }, { "uniprot_ac": "Q86A12", "gene_name": "sky1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86A12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86A12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86A12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86A12" } ] } ] }, { "uniprot_ac": "Q86AE1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86AE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86AE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AE1" } ] } ] }, { "uniprot_ac": "Q86AT8", "gene_name": "spkA-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86AT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86AT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86AT8" } ] } ] }, { "uniprot_ac": "Q86C65", "gene_name": "tor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86C65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86C65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86C65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86C65" } ] } ] }, { "uniprot_ac": "Q86CS2", "gene_name": "atg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86CS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86CS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86CS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86CS2" } ] } ] }, { "uniprot_ac": "Q86HG9", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HG9" } ] } ] }, { "uniprot_ac": "Q86HN7", "gene_name": "PLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HN7" } ] } ] }, { "uniprot_ac": "Q86HW6", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86HW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HW6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86HW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86HW6" } ] } ] }, { "uniprot_ac": "Q86I06", "gene_name": "nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86I06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86I06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86I06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86I06" } ] } ] }, { "uniprot_ac": "Q86IX1", "gene_name": "dst1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86IX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86IX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86IX1" } ] } ] }, { "uniprot_ac": "Q86SG6", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86SG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86SG6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86SG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86SG6" } ] } ] }, { "uniprot_ac": "Q86TB3", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86TB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86TB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86TB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86TB3" } ] } ] }, { "uniprot_ac": "Q86UE8", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86UE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86UE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UE8" } ] } ] }, { "uniprot_ac": "Q86UX6", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86UX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86UX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86UX6" } ] } ] }, { "uniprot_ac": "Q86V86", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86V86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86V86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86V86" } ] } ] }, { "uniprot_ac": "Q86Y07", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86Y07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Y07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86Y07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Y07" } ] } ] }, { "uniprot_ac": "Q86YV6", "gene_name": "MYLK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86YV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86YV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86YV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86YV6" } ] } ] }, { "uniprot_ac": "Q86Z02", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q86Z02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Z02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q86Z02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q86Z02" } ] } ] }, { "uniprot_ac": "Q8BG48", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG48" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BG48" } ] } ] }, { "uniprot_ac": "Q8BGW6", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BGW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGW6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BGW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BGW6" } ] } ] }, { "uniprot_ac": "Q8BHI9", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BHI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BHI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BHI9" } ] } ] }, { "uniprot_ac": "Q8BI55", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BI55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BI55" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q8BI55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BI55" } ] } ] }, { "uniprot_ac": "Q8BK63", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BK63" } ] } ] }, { "uniprot_ac": "Q8BKX6", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BKX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BKX6" } ] } ] }, { "uniprot_ac": "Q8BLF2", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BLF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLF2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8BLF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLF2" } ] } ] }, { "uniprot_ac": "Q8BLK9", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BLK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLK9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BLK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BLK9" } ] } ] }, { "uniprot_ac": "Q8BN21", "gene_name": "Vrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BN21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BN21" } ] } ] }, { "uniprot_ac": "Q8BPM2", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BPM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BPM2" } ] } ] }, { "uniprot_ac": "Q8BRK8", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] }, { "ec_number": "2.7.11.31", "activity": "ATP + L-seryl-[acetyl-CoA carboxylase] = ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase].", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BRK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BRK8" } ] } ] }, { "uniprot_ac": "Q8BSK8", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BSK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BSK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BSK8" } ] } ] }, { "uniprot_ac": "Q8BTH8", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTH8" } ] } ] }, { "uniprot_ac": "Q8BTI9", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q8BTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTI9" } ] } ] }, { "uniprot_ac": "Q8BTW9", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BTW9" } ] } ] }, { "uniprot_ac": "Q8BVP5", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BVP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BVP5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BVP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BVP5" } ] } ] }, { "uniprot_ac": "Q8BW96", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BW96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BW96" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8BW96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BW96" } ] } ] }, { "uniprot_ac": "Q8BWD8", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWD8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8BWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWD8" } ] } ] }, { "uniprot_ac": "Q8BWE1", "gene_name": "1810024B03Rik", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWE1" } ] } ] }, { "uniprot_ac": "Q8BWQ5", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BWQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWQ5" } ] } ] }, { "uniprot_ac": "Q8BWW9", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWW9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8BWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BWW9" } ] } ] }, { "uniprot_ac": "Q8BYC6", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYC6" } ] } ] }, { "uniprot_ac": "Q8BYR2", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BYR2" } ] } ] }, { "uniprot_ac": "Q8BZ03", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ03" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ03" } ] } ] }, { "uniprot_ac": "Q8BZ25", "gene_name": "Ankk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ25" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BZ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZ25" } ] } ] }, { "uniprot_ac": "Q8BZN4", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8BZN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8BZN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8BZN4" } ] } ] }, { "uniprot_ac": "Q8C015", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C015", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C015" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C015", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C015" } ] } ] }, { "uniprot_ac": "Q8C050", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C050" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C050", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C050" } ] } ] }, { "uniprot_ac": "Q8C078", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C078" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8C078", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C078" } ] } ] }, { "uniprot_ac": "Q8C0N0", "gene_name": "Gm4922", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0N0" } ] } ] }, { "uniprot_ac": "Q8C0P0", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0P0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0P0" } ] } ] }, { "uniprot_ac": "Q8C0Q4", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0Q4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0Q4" } ] } ] }, { "uniprot_ac": "Q8C0V0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V0" } ] } ] }, { "uniprot_ac": "Q8C0V7", "gene_name": "Stk-ps2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0V7" } ] } ] }, { "uniprot_ac": "Q8C0X8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0X8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C0X8" } ] } ] }, { "uniprot_ac": "Q8C1R0", "gene_name": "Tssk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C1R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C1R0" } ] } ] }, { "uniprot_ac": "Q8C4X2", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8C4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C4X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8C4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8C4X2" } ] } ] }, { "uniprot_ac": "Q8CDB0", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CDB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CDB0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CDB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CDB0" } ] } ] }, { "uniprot_ac": "Q8CE90", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CE90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE90" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q8CE90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CE90" } ] } ] }, { "uniprot_ac": "Q8CEE6", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CEE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CEE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEE6" } ] } ] }, { "uniprot_ac": "Q8CEQ0", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEQ0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8CEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CEQ0" } ] } ] }, { "uniprot_ac": "Q8CFH6", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFH6" } ] } ] }, { "uniprot_ac": "Q8CIN4", "gene_name": "Pak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIN4" } ] } ] }, { "uniprot_ac": "Q8CIP4", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CIP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIP4" } ] } ] }, { "uniprot_ac": "Q8CIR4", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8CIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8CIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CIR4" } ] } ] }, { "uniprot_ac": "Q8IMC6", "gene_name": "Asator", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IMC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IMC6" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IMC6" } ] } ] }, { "uniprot_ac": "Q8INB9", "gene_name": "Akt", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8INB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8INB9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8INB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8INB9" } ] } ] }, { "uniprot_ac": "Q8IR79", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IR79" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IR79" } ] }, { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q8IR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IR79" } ] } ] }, { "uniprot_ac": "Q8IU85", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IU85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IU85" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8IU85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IU85" } ] } ] }, { "uniprot_ac": "Q8IVH8", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IVH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IVH8" } ] } ] }, { "uniprot_ac": "Q8IVT5", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IVT5" } ] } ] }, { "uniprot_ac": "Q8IVW4", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IVW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IVW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8IVW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IVW4" } ] } ] }, { "uniprot_ac": "Q8IW41", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IW41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IW41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IW41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IW41" } ] } ] }, { "uniprot_ac": "Q8IWQ3", "gene_name": "BRSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IWQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IWQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IWQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IWQ3" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8IWQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IWQ3" } ] } ] }, { "uniprot_ac": "Q8IWU2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IWU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IWU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IWU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IWU2" } ] } ] }, { "uniprot_ac": "Q8IXL6", "gene_name": "FAM20C", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IXL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IXL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IXL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IXL6" } ] } ] }, { "uniprot_ac": "Q8IY84", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IY84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IY84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IY84" } ] } ] }, { "uniprot_ac": "Q8IYT8", "gene_name": "ULK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IYT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IYT8" } ] } ] }, { "uniprot_ac": "Q8IZL9", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8IZL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IZL9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8IZL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8IZL9" } ] } ] }, { "uniprot_ac": "Q8K045", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8K045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K045" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8K045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K045" } ] } ] }, { "uniprot_ac": "Q8K0D0", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8K0D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K0D0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8K0D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K0D0" } ] } ] }, { "uniprot_ac": "Q8K1R7", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8K1R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K1R7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8K1R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K1R7" } ] } ] }, { "uniprot_ac": "Q8K1Y2", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8K1Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K1Y2" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q8K1Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K1Y2" } ] } ] }, { "uniprot_ac": "Q8K3H5", "gene_name": "Myo3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8K3H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K3H5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8K3H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8K3H5" } ] } ] }, { "uniprot_ac": "Q8MSQ4", "gene_name": "Mekk1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8MSQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MSQ4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q8MSQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MSQ4" } ] } ] }, { "uniprot_ac": "Q8MVR1", "gene_name": "gbpC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8MVR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MVR1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8MVR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MVR1" } ] } ] }, { "uniprot_ac": "Q8MYF1", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8MYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MYF1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8MYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8MYF1" } ] } ] }, { "uniprot_ac": "Q8N165", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N165" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N165" } ] } ] }, { "uniprot_ac": "Q8N2I9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N2I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N2I9" } ] } ] }, { "uniprot_ac": "Q8N4C8", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N4C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N4C8" } ] } ] }, { "uniprot_ac": "Q8N568", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N568" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N568", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N568" } ] } ] }, { "uniprot_ac": "Q8N5S9", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N5S9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8N5S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N5S9" } ] } ] }, { "uniprot_ac": "Q8N752", "gene_name": "CSNK1A1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N752" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8N752" } ] } ] }, { "uniprot_ac": "Q8NE63", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NE63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NE63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NE63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NE63" } ] } ] }, { "uniprot_ac": "Q8NEV1", "gene_name": "CSNK2A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV1" } ] } ] }, { "uniprot_ac": "Q8NEV4", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NEV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NEV4" } ] } ] }, { "uniprot_ac": "Q8NFD2", "gene_name": "ANKK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NFD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NFD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NFD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NFD2" } ] } ] }, { "uniprot_ac": "Q8NG66", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8NG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NG66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8NG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8NG66" } ] } ] }, { "uniprot_ac": "Q8QZR7", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZR7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZR7" } ] } ] }, { "uniprot_ac": "Q8QZV4", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZV4" } ] } ] }, { "uniprot_ac": "Q8QZX0", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8QZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZX0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8QZX0" } ] } ] }, { "uniprot_ac": "Q8R2S1", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2S1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R2S1" } ] } ] }, { "uniprot_ac": "Q8R3L8", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q8R3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R3L8" } ] } ] }, { "uniprot_ac": "Q8R4K2", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4K2" } ] } ] }, { "uniprot_ac": "Q8R4U9", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4U9" } ] } ] }, { "uniprot_ac": "Q8R4V0", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8R4V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8R4V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8R4V0" } ] } ] }, { "uniprot_ac": "Q8SSS9", "gene_name": "qkgA-2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSS9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8SSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSS9" } ] } ] }, { "uniprot_ac": "Q8SSV3", "gene_name": "mkcD", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8SSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSV3" } ] } ] }, { "uniprot_ac": "Q8SSY6", "gene_name": "", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q8SSY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSY6" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8SSY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8SSY6" } ] } ] }, { "uniprot_ac": "Q8T0S6", "gene_name": "hpo", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T0S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T0S6" } ] } ] }, { "uniprot_ac": "Q8T2I8", "gene_name": "sepA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T2I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T2I8" } ] } ] }, { "uniprot_ac": "Q8T9L5", "gene_name": "Lkb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8T9L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T9L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8T9L5" } ] } ] }, { "uniprot_ac": "Q8TAS1", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TAS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TAS1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TAS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TAS1" } ] } ] }, { "uniprot_ac": "Q8TD08", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD08" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q8TD08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD08" } ] } ] }, { "uniprot_ac": "Q8TD19", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TD19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TD19" } ] } ] }, { "uniprot_ac": "Q8TDC3", "gene_name": "BRSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8TDC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDC3" } ] } ] }, { "uniprot_ac": "Q8TDR2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TDR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDR2" } ] } ] }, { "uniprot_ac": "Q8TDX7", "gene_name": "NEK7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDX7" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q8TDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TDX7" } ] } ] }, { "uniprot_ac": "Q8TF76", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8TF76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8TF76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8TF76" } ] } ] }, { "uniprot_ac": "Q8VBY2", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VBY2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q8VBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VBY2" } ] } ] }, { "uniprot_ac": "Q8VCT9", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VCT9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q8VCT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VCT9" } ] } ] }, { "uniprot_ac": "Q8VD65", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VD65" } ] } ] }, { "uniprot_ac": "Q8VDF3", "gene_name": "Dapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VDF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDF3" } ] } ] }, { "uniprot_ac": "Q8VDG6", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDG6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q8VDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDG6" } ] } ] }, { "uniprot_ac": "Q8VDU5", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VDU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VDU5" } ] } ] }, { "uniprot_ac": "Q8VHF0", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VHF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VHF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHF0" } ] } ] }, { "uniprot_ac": "Q8VHJ5", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q8VHJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8VHJ5" } ] } ] }, { "uniprot_ac": "Q8WU08", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WU08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WU08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WU08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WU08" } ] } ] }, { "uniprot_ac": "Q8WXR4", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WXR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WXR4" } ] } ] }, { "uniprot_ac": "Q8WZ42", "gene_name": "TTN", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q8WZ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WZ42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8WZ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8WZ42" } ] } ] }, { "uniprot_ac": "Q91VB2", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91VB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VB2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q91VB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VB2" } ] } ] }, { "uniprot_ac": "Q91VJ4", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91VJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91VJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VJ4" } ] } ] }, { "uniprot_ac": "Q91XS8", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91XS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91XS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91XS8" } ] } ] }, { "uniprot_ac": "Q91Y86", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Y86" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q91Y86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Y86" } ] } ] }, { "uniprot_ac": "Q91YA2", "gene_name": "Pskh1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91YA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91YA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YA2" } ] } ] }, { "uniprot_ac": "Q91YS8", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91YS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YS8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q91YS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91YS8" } ] } ] }, { "uniprot_ac": "Q91Z96", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91Z96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91Z96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91Z96" } ] } ] }, { "uniprot_ac": "Q91ZB0", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZB0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZB0" } ] } ] }, { "uniprot_ac": "Q91ZN7", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.4.99.18", "activity": "a dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = a dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-[protein].", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] }, { "ec_number": "2.4.99.18", "activity": "", "evidence": [ { "id": "Q91ZN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZN7" } ] } ] }, { "uniprot_ac": "Q91ZR4", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q91ZR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q91ZR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91ZR4" } ] } ] }, { "uniprot_ac": "Q922Q2", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q922Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Q2" } ] } ] }, { "uniprot_ac": "Q922R0", "gene_name": "Prkx", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q922R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922R0" } ] } ] }, { "uniprot_ac": "Q922Y0", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q922Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Y0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q922Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q922Y0" } ] } ] }, { "uniprot_ac": "Q923J1", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q923J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923J1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q923J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923J1" } ] } ] }, { "uniprot_ac": "Q923T9", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q923T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923T9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q923T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q923T9" } ] } ] }, { "uniprot_ac": "Q924C5", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924C5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924C5" } ] } ] }, { "uniprot_ac": "Q924I2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924I2" } ] } ] }, { "uniprot_ac": "Q924U5", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924U5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q924U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924U5" } ] } ] }, { "uniprot_ac": "Q924X7", "gene_name": "Stk33", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q924X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q924X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q924X7" } ] } ] }, { "uniprot_ac": "Q925B3", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925B3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q925B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925B3" } ] } ] }, { "uniprot_ac": "Q925D6", "gene_name": "Map2k6", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925D6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q925D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925D6" } ] } ] }, { "uniprot_ac": "Q925K9", "gene_name": "Tssk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q925K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925K9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q925K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q925K9" } ] } ] }, { "uniprot_ac": "Q92630", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92630" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q92630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92630" } ] } ] }, { "uniprot_ac": "Q92772", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92772" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q92772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92772" } ] } ] }, { "uniprot_ac": "Q92918", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q92918", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92918" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q92918", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q92918" } ] } ] }, { "uniprot_ac": "Q94533", "gene_name": "S6k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q94533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q94533" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q94533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q94533" } ] } ] }, { "uniprot_ac": "Q95SH0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95SH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95SH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95SH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95SH0" } ] } ] }, { "uniprot_ac": "Q95TN8", "gene_name": "gwl", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95TN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95TN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95TN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95TN8" } ] } ] }, { "uniprot_ac": "Q95UN8", "gene_name": "slpr", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95UN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95UN8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q95UN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95UN8" } ] } ] }, { "uniprot_ac": "Q95YH0", "gene_name": "cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q95YH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q95YH0" } ] } ] }, { "uniprot_ac": "Q96BR1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96BR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96BR1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96BR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96BR1" } ] } ] }, { "uniprot_ac": "Q96C45", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96C45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96C45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96C45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96C45" } ] } ] }, { "uniprot_ac": "Q96GD4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96GD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96GD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GD4" } ] } ] }, { "uniprot_ac": "Q96GX5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96GX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GX5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96GX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96GX5" } ] } ] }, { "uniprot_ac": "Q96J92", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96J92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96J92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96J92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96J92" } ] } ] }, { "uniprot_ac": "Q96KB5", "gene_name": "PBK", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96KB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96KB5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q96KB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96KB5" } ] } ] }, { "uniprot_ac": "Q96L34", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96L34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96L34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L34" } ] } ] }, { "uniprot_ac": "Q96L96", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96L96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96L96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96L96" } ] } ] }, { "uniprot_ac": "Q96LW2", "gene_name": "RSKR", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96LW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96LW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96LW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96LW2" } ] } ] }, { "uniprot_ac": "Q96NX5", "gene_name": "CAMK1G", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96NX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96NX5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q96NX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96NX5" } ] } ] }, { "uniprot_ac": "Q96PF2", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96PF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96PF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PF2" } ] } ] }, { "uniprot_ac": "Q96PN8", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96PN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96PN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PN8" } ] } ] }, { "uniprot_ac": "Q96PU5", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q96PU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PU5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q96PU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PU5" } ] }, { "ec_number": "2.3.2.36", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-S-ubiquitinyl-L-cysteine.", "evidence": [ { "id": "Q96PU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PU5" } ] }, { "ec_number": "2.3.2.36", "activity": "", "evidence": [ { "id": "Q96PU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PU5" } ] } ] }, { "uniprot_ac": "Q96PY6", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96PY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96PY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96PY6" } ] } ] }, { "uniprot_ac": "Q96Q04", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96Q04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96Q04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96Q04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96Q04" } ] } ] }, { "uniprot_ac": "Q96Q15", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96Q15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96Q15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96Q15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96Q15" } ] } ] }, { "uniprot_ac": "Q96Q40", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96Q40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96Q40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q96Q40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96Q40" } ] } ] }, { "uniprot_ac": "Q96QP1", "gene_name": "ALPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96QP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96QP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96QP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96QP1" } ] } ] }, { "uniprot_ac": "Q96QS6", "gene_name": "PSKH2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96QS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96QS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96QS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96QS6" } ] } ] }, { "uniprot_ac": "Q96QT4", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96QT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96QT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96QT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96QT4" } ] } ] }, { "uniprot_ac": "Q96RG2", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96RG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96RG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96RG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96RG2" } ] } ] }, { "uniprot_ac": "Q96RR4", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96RR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96RR4" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q96RR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96RR4" } ] } ] }, { "uniprot_ac": "Q96S38", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96S38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96S38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S38" } ] } ] }, { "uniprot_ac": "Q96S44", "gene_name": "TP53RK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96S44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S44" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q96S44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96S44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S44" } ] } ] }, { "uniprot_ac": "Q96S53", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96S53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q96S53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96S53" } ] } ] }, { "uniprot_ac": "Q96SB4", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q96SB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96SB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q96SB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q96SB4" } ] } ] }, { "uniprot_ac": "Q99558", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99558", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99558" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q99558", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99558" } ] } ] }, { "uniprot_ac": "Q99570", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99570" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99570" } ] } ] }, { "uniprot_ac": "Q99640", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99640", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99640" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99640", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99640" } ] } ] }, { "uniprot_ac": "Q99683", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99683" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q99683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99683" } ] } ] }, { "uniprot_ac": "Q99759", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99759" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q99759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99759" } ] } ] }, { "uniprot_ac": "Q99986", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99986" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99986" } ] } ] }, { "uniprot_ac": "Q99J82", "gene_name": "Ilk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99J82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J82" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99J82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J82" } ] } ] }, { "uniprot_ac": "Q99J95", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99J95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J95" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q99J95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J95" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q99J95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J95" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q99J95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99J95" } ] } ] }, { "uniprot_ac": "Q99JP0", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99JP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99JP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JP0" } ] } ] }, { "uniprot_ac": "Q99JT2", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99JT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99JT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99JT2" } ] } ] }, { "uniprot_ac": "Q99KH8", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99KH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KH8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99KH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KH8" } ] } ] }, { "uniprot_ac": "Q99KY4", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KY4" } ] } ] }, { "uniprot_ac": "Q99MQ3", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99MQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99MQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MQ3" } ] } ] }, { "uniprot_ac": "Q99MW1", "gene_name": "Stk31", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99MW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99MW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99MW1" } ] } ] }, { "uniprot_ac": "Q99N57", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99N57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N57" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99N57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99N57" } ] } ] }, { "uniprot_ac": "Q99PW4", "gene_name": "Tp53rkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q99PW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PW4" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q99PW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q99PW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99PW4" } ] } ] }, { "uniprot_ac": "Q9BQI3", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BQI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BQI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BQI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BQI3" } ] } ] }, { "uniprot_ac": "Q9BRS2", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] }, { "ec_number": "3.6.3.-", "activity": "", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BRS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BRS2" } ] } ] }, { "uniprot_ac": "Q9BUB5", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BUB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BUB5" } ] } ] }, { "uniprot_ac": "Q9BVS4", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BVS4" } ] } ] }, { "uniprot_ac": "Q9BWU1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BWU1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9BWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BWU1" } ] } ] }, { "uniprot_ac": "Q9BX84", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BX84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BX84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BX84" } ] } ] }, { "uniprot_ac": "Q9BXA6", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA6" } ] } ] }, { "uniprot_ac": "Q9BXA7", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXA7" } ] } ] }, { "uniprot_ac": "Q9BXM7", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXM7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXM7" } ] } ] }, { "uniprot_ac": "Q9BXU1", "gene_name": "STK31", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BXU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BXU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BXU1" } ] } ] }, { "uniprot_ac": "Q9BYP7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYP7" } ] } ] }, { "uniprot_ac": "Q9BYT3", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9BYT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BYT3" } ] } ] }, { "uniprot_ac": "Q9BZL6", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9BZL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BZL6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9BZL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9BZL6" } ] } ] }, { "uniprot_ac": "Q9C098", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9C098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9C098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9C098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9C098" } ] } ] }, { "uniprot_ac": "Q9CQS5", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9CQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9CQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CQS5" } ] } ] }, { "uniprot_ac": "Q9CXB8", "gene_name": "Alpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9CXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CXB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9CXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CXB8" } ] } ] }, { "uniprot_ac": "Q9D2E1", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9D2E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D2E1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9D2E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D2E1" } ] } ] }, { "uniprot_ac": "Q9D411", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9D411", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D411" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9D411", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D411" } ] } ] }, { "uniprot_ac": "Q9DBU3", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9DBU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9DBU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DBU3" } ] } ] }, { "uniprot_ac": "Q9DC28", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q9DC28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9DC28" } ] } ] }, { "uniprot_ac": "Q9EQY0", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9EQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9EQY0" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q9EQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9EQY0" } ] } ] }, { "uniprot_ac": "Q9ERE3", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ERE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERE3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ERE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERE3" } ] } ] }, { "uniprot_ac": "Q9ERH7", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ERH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ERH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERH7" } ] } ] }, { "uniprot_ac": "Q9ERK0", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ERK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ERK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ERK0" } ] } ] }, { "uniprot_ac": "Q9ES70", "gene_name": "Nek6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ES70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES70" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9ES70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES70" } ] } ] }, { "uniprot_ac": "Q9ES74", "gene_name": "Nek7", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ES74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES74" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9ES74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ES74" } ] } ] }, { "uniprot_ac": "Q9ESG9", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ESG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9ESG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESG9" } ] } ] }, { "uniprot_ac": "Q9ESL4", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9ESL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESL4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9ESL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9ESL4" } ] } ] }, { "uniprot_ac": "Q9H093", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H093" } ] } ] }, { "uniprot_ac": "Q9H0K1", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H0K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H0K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H0K1" } ] } ] }, { "uniprot_ac": "Q9H0M0", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9H0M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H0M0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9H0M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H0M0" } ] } ] }, { "uniprot_ac": "Q9H2G2", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2G2" } ] } ] }, { "uniprot_ac": "Q9H2K8", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2K8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2K8" } ] } ] }, { "uniprot_ac": "Q9H2X6", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H2X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2X6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H2X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H2X6" } ] } ] }, { "uniprot_ac": "Q9H422", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H422" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H422" } ] } ] }, { "uniprot_ac": "Q9H4A3", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H4A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4A3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9H4A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4A3" } ] } ] }, { "uniprot_ac": "Q9H4B4", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9H4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4B4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q9H4B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9H4B4" } ] } ] }, { "uniprot_ac": "Q9HAZ1", "gene_name": "CLK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HAZ1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9HAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HAZ1" } ] } ] }, { "uniprot_ac": "Q9HBH9", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HBH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBH9" } ] } ] }, { "uniprot_ac": "Q9HBY8", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HBY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HBY8" } ] } ] }, { "uniprot_ac": "Q9HC98", "gene_name": "NEK6", "activity": [ { "ec_number": "2.7.11.34", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HC98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HC98" } ] }, { "ec_number": "2.7.11.34", "activity": "", "evidence": [ { "id": "Q9HC98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HC98" } ] } ] }, { "uniprot_ac": "Q9HCP0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9HCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HCP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9HCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9HCP0" } ] } ] }, { "uniprot_ac": "Q9JHG7", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "Q9JHG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHG7" } ] } ] }, { "uniprot_ac": "Q9JHU3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHU3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JHU3" } ] } ] }, { "uniprot_ac": "Q9JI10", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JI10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI10" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JI10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI10" } ] } ] }, { "uniprot_ac": "Q9JI11", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JI11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JI11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JI11" } ] } ] }, { "uniprot_ac": "Q9JIH7", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JIH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JIH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIH7" } ] } ] }, { "uniprot_ac": "Q9JIX9", "gene_name": "Fastk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.8", "activity": "ATP + L-threonyl-[Fas-activated protein] = ADP + H(+) + O-phospho-L-threonyl-[Fas-activated protein].", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.8", "activity": "", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JIX9" } ] } ] }, { "uniprot_ac": "Q9JJ78", "gene_name": "Pbk", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJ78" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q9JJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJ78" } ] } ] }, { "uniprot_ac": "Q9JJX8", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JJX8" } ] } ] }, { "uniprot_ac": "Q9JKK8", "gene_name": "Atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKK8" } ] } ] }, { "uniprot_ac": "Q9JKV2", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JKV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JKV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JKV2" } ] } ] }, { "uniprot_ac": "Q9JLM8", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLM8" } ] } ] }, { "uniprot_ac": "Q9JLN9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLN9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLN9" } ] } ] }, { "uniprot_ac": "Q9JLS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JLS3" } ] } ] }, { "uniprot_ac": "Q9JM01", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM01" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9JM01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM01" } ] } ] }, { "uniprot_ac": "Q9JM52", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JM52" } ] } ] }, { "uniprot_ac": "Q9JMK2", "gene_name": "Csnk1e", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9JMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JMK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9JMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9JMK2" } ] } ] }, { "uniprot_ac": "Q9NBK5", "gene_name": "trc", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NBK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NBK5" } ] } ] }, { "uniprot_ac": "Q9NGW9", "gene_name": "mkcB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NGW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NGW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NGW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NGW9" } ] } ] }, { "uniprot_ac": "Q9NI63", "gene_name": "Myt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NI63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NI63" } ] } ] }, { "uniprot_ac": "Q9NIV1", "gene_name": "PEK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NIV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NIV1" } ] } ] }, { "uniprot_ac": "Q9NQU5", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NQU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NQU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NQU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NQU5" } ] } ] }, { "uniprot_ac": "Q9NR20", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NR20" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9NR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NR20" } ] } ] }, { "uniprot_ac": "Q9NRH2", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRH2" } ] } ] }, { "uniprot_ac": "Q9NRM7", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRM7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NRM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRM7" } ] } ] }, { "uniprot_ac": "Q9NRP7", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NRP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NRP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NRP7" } ] } ] }, { "uniprot_ac": "Q9NSY1", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NSY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NSY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NSY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NSY1" } ] } ] }, { "uniprot_ac": "Q9NWZ3", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NWZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NWZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NWZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NWZ3" } ] } ] }, { "uniprot_ac": "Q9NY57", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NY57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NY57" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NY57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NY57" } ] } ] }, { "uniprot_ac": "Q9NYL2", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NYL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYL2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9NYL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYL2" } ] } ] }, { "uniprot_ac": "Q9NYV4", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NYV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYV4" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9NYV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYV4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9NYV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYV4" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9NYV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYV4" } ] } ] }, { "uniprot_ac": "Q9NYY3", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYY3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q9NYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NYY3" } ] } ] }, { "uniprot_ac": "Q9NZJ5", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9NZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NZJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9NZJ5" } ] } ] }, { "uniprot_ac": "Q9P0L2", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9P0L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P0L2" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q9P0L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P0L2" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q9P0L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P0L2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9P0L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P0L2" } ] } ] }, { "uniprot_ac": "Q9P1W9", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9P1W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P1W9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9P1W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P1W9" } ] } ] }, { "uniprot_ac": "Q9P286", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9P286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P286" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9P286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P286" } ] } ] }, { "uniprot_ac": "Q9P289", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9P289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P289" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9P289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P289" } ] } ] }, { "uniprot_ac": "Q9P2K8", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9P2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P2K8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9P2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9P2K8" } ] } ] }, { "uniprot_ac": "Q9QUK0", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QUK0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9QUK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QUK0" } ] } ] }, { "uniprot_ac": "Q9QY01", "gene_name": "Ulk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QY01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QY01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QY01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QY01" } ] } ] }, { "uniprot_ac": "Q9QY78", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "ATP + L-seryl-[I-kappa-B protein] = ADP + H(+) + O-phospho-L-seryl-[I-kappa-B protein].", "evidence": [ { "id": "Q9QY78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QY78" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QY78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QY78" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q9QY78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QY78" } ] } ] }, { "uniprot_ac": "Q9QYK9", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QYK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYK9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q9QYK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYK9" } ] } ] }, { "uniprot_ac": "Q9QYZ3", "gene_name": "Smok2b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYZ3" } ] } ] }, { "uniprot_ac": "Q9QYZ4", "gene_name": "Smok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYZ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYZ4" } ] } ] }, { "uniprot_ac": "Q9QYZ6", "gene_name": "Smok2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QYZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QYZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYZ6" } ] } ] }, { "uniprot_ac": "Q9QZ05", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZ05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZ05" } ] } ] }, { "uniprot_ac": "Q9QZL0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QZL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QZL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZL0" } ] } ] }, { "uniprot_ac": "Q9QZR5", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QZR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QZR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZR5" } ] } ] }, { "uniprot_ac": "Q9QZS5", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9QZS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9QZS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZS5" } ] } ] }, { "uniprot_ac": "Q9R011", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9R011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R011" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q9R011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R011" } ] } ] }, { "uniprot_ac": "Q9R012", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9R012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R012" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q9R012", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R012" } ] } ] }, { "uniprot_ac": "Q9R0A5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9R0A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R0A5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9R0A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R0A5" } ] } ] }, { "uniprot_ac": "Q9R0G8", "gene_name": "Nrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9R0G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R0G8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9R0G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R0G8" } ] } ] }, { "uniprot_ac": "Q9R1L5", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9R1L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R1L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9R1L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R1L5" } ] } ] }, { "uniprot_ac": "Q9R1U5", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9R1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R1U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9R1U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9R1U5" } ] } ] }, { "uniprot_ac": "Q9UBE8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UBE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UBE8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9UBE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UBE8" } ] } ] }, { "uniprot_ac": "Q9UBS0", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UBS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UBS0" } ] } ] }, { "uniprot_ac": "Q9UEE5", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UEE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UEE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UEE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UEE5" } ] } ] }, { "uniprot_ac": "Q9UEW8", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UEW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UEW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UEW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UEW8" } ] } ] }, { "uniprot_ac": "Q9UHD2", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UHD2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UHD2" } ] } ] }, { "uniprot_ac": "Q9UIK4", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UIK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UIK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UIK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UIK4" } ] } ] }, { "uniprot_ac": "Q9UK32", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UK32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UK32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UK32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UK32" } ] } ] }, { "uniprot_ac": "Q9UKE5", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UKE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UKE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKE5" } ] } ] }, { "uniprot_ac": "Q9UKI8", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UKI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UKI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UKI8" } ] } ] }, { "uniprot_ac": "Q9UL54", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UL54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UL54" } ] } ] }, { "uniprot_ac": "Q9UPE1", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPE1" } ] } ] }, { "uniprot_ac": "Q9UPZ9", "gene_name": "CILK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UPZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPZ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UPZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UPZ9" } ] } ] }, { "uniprot_ac": "Q9UQ07", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ07" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9UQ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ07" } ] } ] }, { "uniprot_ac": "Q9UQ88", "gene_name": "CDK11A", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ88" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9UQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQ88" } ] } ] }, { "uniprot_ac": "Q9UQB9", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQB9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9UQB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQB9" } ] } ] }, { "uniprot_ac": "Q9UQM7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9UQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQM7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q9UQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9UQM7" } ] } ] }, { "uniprot_ac": "Q9V3D5", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3D5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3D5" } ] } ] }, { "uniprot_ac": "Q9V3I5", "gene_name": "JIL-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3I5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3I5" } ] } ] }, { "uniprot_ac": "Q9V3Q6", "gene_name": "Tak1", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3Q6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9V3Q6" } ] } ] }, { "uniprot_ac": "Q9VA38", "gene_name": "wts", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VA38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VA38" } ] } ] }, { "uniprot_ac": "Q9VBU2", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VBU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VBU2" } ] } ] }, { "uniprot_ac": "Q9VCV0", "gene_name": "Takl2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VCV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VCV0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9VCV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VCV0" } ] } ] }, { "uniprot_ac": "Q9VD82", "gene_name": "Dmel\\CG6800", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VD82" } ] } ] }, { "uniprot_ac": "Q9VE06", "gene_name": "cdi", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VE06" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VE06" } ] } ] }, { "uniprot_ac": "Q9VEN3", "gene_name": "GckIII", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VEN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VEN3" } ] } ] }, { "uniprot_ac": "Q9VGF9", "gene_name": "aurA", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VGF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VGF9" } ] } ] }, { "uniprot_ac": "Q9VI13", "gene_name": "Pak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI13" } ] } ] }, { "uniprot_ac": "Q9VI84", "gene_name": "Dmel\\CG1227", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VI84" } ] } ] }, { "uniprot_ac": "Q9VJ30", "gene_name": "Nak", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJ30" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJ30" } ] } ] }, { "uniprot_ac": "Q9VJC2", "gene_name": "Dmel\\CG7094", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VJC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VJC2" } ] } ] }, { "uniprot_ac": "Q9VK45", "gene_name": "mTor", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VK45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VK45" } ] } ] }, { "uniprot_ac": "Q9VKN7", "gene_name": "aurB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VKN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VKN7" } ] } ] }, { "uniprot_ac": "Q9VL34", "gene_name": "Dmel\\CG4839", "activity": [ { "ec_number": "2.7.11.12", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VL34" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VL34" } ] } ] }, { "uniprot_ac": "Q9VM90", "gene_name": "meng", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VM90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VM90" } ] } ] }, { "uniprot_ac": "Q9VMY8", "gene_name": "aux", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VMY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VMY8" } ] } ] }, { "uniprot_ac": "Q9VN23", "gene_name": "CG10532", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VN23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VN23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VN23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VN23" } ] } ] }, { "uniprot_ac": "Q9VP22", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VP22" } ] } ] }, { "uniprot_ac": "Q9VPC0", "gene_name": "Pitslre", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VPC0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VPC0" } ] } ] }, { "uniprot_ac": "Q9VR42", "gene_name": "Dmel\\CG3008", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VR42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VR42" } ] } ] }, { "uniprot_ac": "Q9VRJ6", "gene_name": "Tcs5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VRJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VRJ6" } ] } ] }, { "uniprot_ac": "Q9VT57", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VT57" } ] } ] }, { "uniprot_ac": "Q9VTL5", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VTL5" } ] } ] }, { "uniprot_ac": "Q9VUQ9", "gene_name": "dop", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUQ9" } ] } ] }, { "uniprot_ac": "Q9VUV4", "gene_name": "sff", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VUV4" } ] } ] }, { "uniprot_ac": "Q9VW24", "gene_name": "wnd", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VW24" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VW24" } ] } ] }, { "uniprot_ac": "Q9VXE3", "gene_name": "Rok", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE3" } ] } ] }, { "uniprot_ac": "Q9VXE5", "gene_name": "mbt", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXE5" } ] } ] }, { "uniprot_ac": "Q9VXG8", "gene_name": "mei-41", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXG8" } ] } ] }, { "uniprot_ac": "Q9VXN5", "gene_name": "Dmel\\CG8565", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VXN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VXN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VXN5" } ] } ] }, { "uniprot_ac": "Q9VZI2", "gene_name": "Ack", "activity": [ { "ec_number": "2.7.10.2", "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q9VZI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9VZI2" } ] } ] }, { "uniprot_ac": "Q9W002", "gene_name": "msn", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W002" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W002" } ] } ] }, { "uniprot_ac": "Q9W0V1", "gene_name": "Pdk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W0V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W0V1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W0V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W0V1" } ] } ] }, { "uniprot_ac": "Q9W1B0", "gene_name": "gek", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W1B0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W1B0" } ] } ] }, { "uniprot_ac": "Q9W354", "gene_name": "Erk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W354" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9W354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W354" } ] } ] }, { "uniprot_ac": "Q9W3N8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9W3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W3N8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9W3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W3N8" } ] } ] }, { "uniprot_ac": "Q9WTK7", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WTK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTK7" } ] } ] }, { "uniprot_ac": "Q9WTQ0", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9WTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ0" } ] } ] }, { "uniprot_ac": "Q9WTQ1", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q9WTQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTQ1" } ] } ] }, { "uniprot_ac": "Q9WTR2", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTR2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9WTR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTR2" } ] } ] }, { "uniprot_ac": "Q9WTU6", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTU6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WTU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTU6" } ] } ] }, { "uniprot_ac": "Q9WTY9", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTY9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WTY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WTY9" } ] } ] }, { "uniprot_ac": "Q9WUA6", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUA6" } ] } ] }, { "uniprot_ac": "Q9WUI1", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUI1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WUI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUI1" } ] } ] }, { "uniprot_ac": "Q9WUL6", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUL6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9WUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUL6" } ] } ] }, { "uniprot_ac": "Q9WUN2", "gene_name": "Tbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUN2" } ] } ] }, { "uniprot_ac": "Q9WUT3", "gene_name": "Rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WUT3" } ] } ] }, { "uniprot_ac": "Q9WV60", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] }, { "ec_number": "2.7.11.26", "activity": "ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein].", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "Q9WV60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WV60" } ] } ] }, { "uniprot_ac": "Q9WVC6", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9WVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVC6" } ] } ] }, { "uniprot_ac": "Q9WVS4", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9WVS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS4" } ] } ] }, { "uniprot_ac": "Q9WVS7", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q9WVS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS7" } ] } ] }, { "uniprot_ac": "Q9WVS8", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9WVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9WVS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9WVS8" } ] } ] }, { "uniprot_ac": "Q9Y243", "gene_name": "AKT3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y243" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y243" } ] } ] }, { "uniprot_ac": "Q9Y2H1", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H1" } ] } ] }, { "uniprot_ac": "Q9Y2H9", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2H9" } ] } ] }, { "uniprot_ac": "Q9Y2I7", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "Q9Y2I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2I7" } ] } ] }, { "uniprot_ac": "Q9Y2K2", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2K2" } ] } ] }, { "uniprot_ac": "Q9Y2U5", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2U5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9Y2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y2U5" } ] } ] }, { "uniprot_ac": "Q9Y3S1", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y3S1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y3S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y3S1" } ] } ] }, { "uniprot_ac": "Q9Y463", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y463" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9Y463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y463" } ] } ] }, { "uniprot_ac": "Q9Y4B6", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y4B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4B6" } ] } ] }, { "uniprot_ac": "Q9Y4K4", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y4K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y4K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y4K4" } ] } ] }, { "uniprot_ac": "Q9Y572", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y572" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y572" } ] } ] }, { "uniprot_ac": "Q9Y5S2", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y5S2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y5S2" } ] } ] }, { "uniprot_ac": "Q9Y6E0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y6E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6E0" } ] } ] }, { "uniprot_ac": "Q9Y6M4", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6M4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y6M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6M4" } ] } ] }, { "uniprot_ac": "Q9Y6R4", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6R4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9Y6R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6R4" } ] } ] }, { "uniprot_ac": "Q9Y6S9", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Y6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6S9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Y6S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Y6S9" } ] } ] }, { "uniprot_ac": "Q9Z0G2", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z0G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z0G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0G2" } ] } ] }, { "uniprot_ac": "Q9Z0H0", "gene_name": "Cdc7", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z0H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z0H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0H0" } ] } ] }, { "uniprot_ac": "Q9Z0R0", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0R0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z0R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z0R0" } ] } ] }, { "uniprot_ac": "Q9Z188", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z188" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9Z188", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z188" } ] } ] }, { "uniprot_ac": "Q9Z1B7", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1B7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9Z1B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1B7" } ] } ] }, { "uniprot_ac": "Q9Z1J2", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1J2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1J2" } ] } ] }, { "uniprot_ac": "Q9Z1L0", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1L0" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9Z1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1L0" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "Q9Z1L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1L0" } ] } ] }, { "uniprot_ac": "Q9Z1M4", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1M4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z1M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1M4" } ] } ] }, { "uniprot_ac": "Q9Z1S0", "gene_name": "Bub1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1S0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z1S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1S0" } ] } ] }, { "uniprot_ac": "Q9Z1T6", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1T6" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "Q9Z1T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1T6" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "Q9Z1T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1T6" } ] } ] }, { "uniprot_ac": "Q9Z1W9", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1W9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z1W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1W9" } ] } ] }, { "uniprot_ac": "Q9Z1Z1", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z1Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1Z1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z1Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1Z1" } ] } ] }, { "uniprot_ac": "Q9Z265", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z265" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z265", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z265" } ] } ] }, { "uniprot_ac": "Q9Z2A0", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A0" } ] } ] }, { "uniprot_ac": "Q9Z2A6", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q9Z2A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2A6" } ] } ] }, { "uniprot_ac": "Q9Z2B5", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B5" } ] } ] }, { "uniprot_ac": "Q9Z2B9", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2B9" } ] } ] }, { "uniprot_ac": "Q9Z2E3", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2E3" } ] }, { "ec_number": "3.1.26.-", "activity": "", "evidence": [ { "id": "Q9Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2E3" } ] } ] }, { "uniprot_ac": "Q9Z2P5", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2P5" } ] } ] }, { "uniprot_ac": "Q9Z2R9", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2R9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2R9" } ] } ] }, { "uniprot_ac": "Q9Z2W1", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z2W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2W1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z2W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z2W1" } ] } ] }, { "uniprot_ac": "Q9Z335", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q9Z335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z335" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9Z335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z335" } ] } ] }, { "uniprot_ac": "X2JAG8", "gene_name": "Prp4k", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "X2JAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/X2JAG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "X2JAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/X2JAG8" } ] } ] } ], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 74, 78, 256, 369, 377, 397, 401, 422 ], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 44, "end_pos": 46 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 16 }, { "field": "total_sites", "count": 8 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 333 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }