{
    "uniprot_canonical_ac": "E5RIL1-1",
    "uniprot_ac": "E5RIL1",
    "uniprot_id": "UPKL2_HUMAN",
    "mass": {
        "chemical_mass": 28385.0,
        "monoisotopic_mass": 28385.0
    },
    "refseq": {
        "ac": "NP_001107875",
        "name": "uroplakin-3b-like protein 1 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107875"
    },
    "gene_names": [
        {
            "name": "UPK3BL2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/E5RIL1",
            "id": "E5RIL1"
        },
        {
            "name": "UPK3BL1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107875",
            "id": "NP_001107875"
        },
        {
            "name": "UPK3BL; UPLP",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107875",
            "id": "NP_001107875"
        }
    ],
    "protein_names": [
        {
            "name": "Uroplakin-3b-like protein 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "E5RIL1"
        },
        {
            "name": "uroplakin-3b-like protein 1 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107875",
            "id": "NP_001107875"
        },
        {
            "name": "uroplakin-like protein; uroplakin-3-like protein; uroplakin 3C protein; uroplakin-3b-like protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107875",
            "id": "NP_001107875"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [
        {
            "evidence": [
                {
                    "id": "rs1586800438",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1586800438"
                },
                {
                    "id": "rs1586800438",
                    "database": "ENSEMBL",
                    "url": "https://www.ensembl.org/id/rs1586800438"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-loss"
            ],
            "start_pos": 140,
            "end_pos": 140,
            "sequence_org": "N",
            "sequence_mut": "S",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->SDT).",
            "chr_id": "7",
            "chr_pos": "102541159",
            "ref_nt": "C",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "N140",
            "keywords": [
                "ebi",
                "germline"
            ]
        },
        {
            "evidence": [
                {
                    "id": "rs1191900669",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1191900669"
                },
                {
                    "id": "rs1191900669",
                    "database": "TOPMed",
                    "url": "https://www.ncbi.nlm.nih.gov/snp/rs1191900669#frequency_tab"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-gain",
                "o-glyco-site-loss"
            ],
            "start_pos": 181,
            "end_pos": 181,
            "sequence_org": "S",
            "sequence_mut": "N",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (SDT->NDT).",
            "chr_id": "7",
            "chr_pos": "102540035",
            "ref_nt": "T",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "S181",
            "keywords": [
                "ebi",
                "germline"
            ]
        },
        {
            "evidence": [
                {
                    "id": "rs1230144963",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1230144963"
                },
                {
                    "id": "rs1230144963",
                    "database": "TOPMed",
                    "url": "https://www.ncbi.nlm.nih.gov/snp/rs1230144963#frequency_tab"
                },
                {
                    "id": "rs1230144963",
                    "database": "gnomAD",
                    "url": "http://gnomad.broadinstitute.org/awesome?query=rs1230144963"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-loss",
                "o-glyco-site-loss"
            ],
            "start_pos": 53,
            "end_pos": 53,
            "sequence_org": "T",
            "sequence_mut": "I",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->NDI).",
            "chr_id": "7",
            "chr_pos": "102541617",
            "ref_nt": "A",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "T53",
            "keywords": [
                "ebi",
                "germline"
            ]
        },
        {
            "evidence": [
                {
                    "id": "rs1586800820",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1586800820"
                },
                {
                    "id": "rs1586800820",
                    "database": "ENSEMBL",
                    "url": "https://www.ensembl.org/id/rs1586800820"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-loss",
                "o-glyco-site-loss"
            ],
            "start_pos": 53,
            "end_pos": 53,
            "sequence_org": "T",
            "sequence_mut": "P",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NDT->NDP).",
            "chr_id": "7",
            "chr_pos": "102541618",
            "ref_nt": "G",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "T53",
            "keywords": [
                "ebi",
                "germline"
            ]
        }
    ],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "E5RIL1",
                    "url": "https://www.uniprot.org/uniprot/E5RIL1"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "UPK3BL2",
            "url": "https://www.uniprot.org/uniprot/E5RIL1",
            "locus": {
                "chromosome": "7",
                "start_pos": 102537919,
                "end_pos": 102543696,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000284981",
                        "url": "https://www.ensembl.org/id/ENSG00000284981"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000284981",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000284981",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "UPK3BL2",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=UPK3BL2",
            "database": "GeneCards",
            "categories": [
                "Gene Annotation",
                "Organism-specific"
            ]
        },
        {
            "id": "100134938",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100134938",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "53444",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=53444",
            "database": "HGNC",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "IPR024831",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR024831",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "hsa:100134938",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:100134938",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "NX_E5RIL1",
            "url": "https://www.nextprot.org/entry/NX_E5RIL1",
            "database": "neXtProt",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "HTWAGSA",
            "url": "https://omabrowser.org/oma/group/HTWAGSA/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5318376at2759",
            "url": "http://www.orthodb.org/?query=5318376at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15446",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15446",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15446:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15446:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "E5RIL1",
            "url": "https://pharos.nih.gov/targets/E5RIL1",
            "database": "PHAROS",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "PR_E5RIL1",
            "url": "http://purl.obolibrary.org/obo/PR_E5RIL1",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001107875",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107875",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E5RIL1",
            "url": "https://www.uniprot.org/uniprot/E5RIL1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E5RIL1-1",
            "url": "https://www.uniprot.org/uniprot/E5RIL1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MDNSWRLGPAIGLSAGQSQLLVSLLLLLTRVQPGTDVAAPEHISYVPQLSNDTLAGRLTLSTFTLEQPLGQFSSHNISDLDTIWLVVALSNATQSFTAPRTNQDIPAPANFSQRGYYLTLRANRVLYQTRGQLHVLRVGNDTHCQPTKIGCNHPLPGPGPYRVKFLVMNDEGPVAETKWSSDTRLQQAQALRAVPGPQSPGTVVIIAILSILLAVLLTVLLAVLIYTCFNSCRSTSLSGPEEAGSVRRYTTHLAFSTPAEGAS",
        "length": 263,
        "header": "sp|E5RIL1-1|UPKL2_HUMAN Isoform 1 of Uroplakin-3b-like protein 2  OS=Homo sapiens OX=9606 GN=UPK3BL2 PE=3 SV=2 CANONICAL=E5RIL1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "E5RIL1-1",
            "url": "",
            "sequence": {
                "sequence": "MDNSWRLGPAIGLSAGQSQLLVSLLLLLTRVQPGTDVAAPEHISYVPQLSNDTLAGRLTLSTFTLEQPLGQFSSHNISDLDTIWLVVALSNATQSFTAPRTNQDIPAPANFSQRGYYLTLRANRVLYQTRGQLHVLRVGNDTHCQPTKIGCNHPLPGPGPYRVKFLVMNDEGPVAETKWSSDTRLQQAQALRAVPGPQSPGTVVIIAILSILLAVLLTVLLAVLIYTCFNSCRSTSLSGPEEAGSVRRYTTHLAFSTPAEGAS",
                "length": 263,
                "header": "sp|E5RIL1-1|UPKL2_HUMAN Isoform 1 of Uroplakin-3b-like protein 2  OS=Homo sapiens OX=9606 GN=UPK3BL2 PE=3 SV=2 CANONICAL=E5RIL1-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 102543636,
                "end_pos": 102538420,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000644544.2",
                        "url": "https://www.ensembl.org/id/ENST00000644544.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000494359.1",
                        "url": "https://www.ensembl.org/id/ENSP00000494359.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
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            "start_aa": "Asn",
            "end_pos": 110,
            "end_aa": "Asn",
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            "site_lbl": "Asn110",
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                {
                    "id": "E5RIL1",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/E5RIL1#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 140,
            "start_aa": "Asn",
            "end_pos": 140,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn140",
            "evidence": [
                {
                    "id": "E5RIL1",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/E5RIL1#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 51,
            "start_aa": "Asn",
            "end_pos": 51,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn51",
            "evidence": [
                {
                    "id": "E5RIL1",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/E5RIL1#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 76,
            "start_aa": "Asn",
            "end_pos": 76,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn76",
            "evidence": [
                {
                    "id": "E5RIL1",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/E5RIL1#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 91,
            "start_aa": "Asn",
            "end_pos": 91,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn91",
            "evidence": [
                {
                    "id": "E5RIL1",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/E5RIL1#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [],
    "pathway": [
        {
            "id": "hsa:100134938",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:100134938",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZXT5-1",
            "protein_name": "Uroplakin 3B like 1",
            "gene_name": "Upk3bl1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MGPHRKQSMLLLPLLVLVTCVQPGTGLESINYVPQLPSATLEGRLTQSTFTLEQPLDQFKNVNLSDADPIWLVVARSDTAQNFTAPRKVEDRHAPAHFDDNGYYLTLRASRVHYKGSQNDSRLPVLRVGNDNNCSVRSQGCNSPLPGPGPYRVKFLAMNAKGPVAETLWSKDIYLQQAQTFRGAPGSQSKGTVVIIAFSSILLAILLAVFLMLVISACCSSTSVSSPEEQVRMRRYHTHHVGSLPAERSS",
                "length": 250
            },
            "evidence": [
                {
                    "id": "45920777",
                    "url": "http://www.informatics.jax.org/homology/45920777",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9D701-1",
            "protein_name": "Uroplakin-3b-like protein 1",
            "gene_name": "Upk3bl1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MGPHGKQSVLRMPLLLLLTCVQSGTGLESINYAPQLLGATLEGRLTQSTFTLEQPLGQFKNVNLSDPDPIWLVVAHSNAAQNFTAPRKVEDRHAPANFDRNGYYLTLRANRVHYKGGQPDSQLRVLRVGNDNNCSLESQGCNSPLPGAGPYRVKFLAMSAEGPVAETLWSEEIYLQQAQTFREAPGSQGKGTVVIIAFLSILLAILLVVFLVLVISACLSTSGSSPEEQVRMRHYHTHHMGSLRAERSS",
                "length": 249
            },
            "evidence": [
                {
                    "id": "45920777",
                    "url": "http://www.informatics.jax.org/homology/45920777",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E5RIL1",
                                "url": "https://www.uniprot.org/uniprot/E5RIL1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 110,
            "end_pos": 112,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 140,
            "end_pos": 142,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 51,
            "end_pos": 53,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 76,
            "end_pos": 78,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 91,
            "end_pos": 93,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [
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            76,
            91,
            110,
            140
        ],
        "o_linked_sites": [],
        "snv_sites": [
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            140,
            181
        ],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 110,
                "end_pos": 112
            },
            {
                "start_pos": 140,
                "end_pos": 142
            },
            {
                "start_pos": 51,
                "end_pos": 53
            },
            {
                "start_pos": 76,
                "end_pos": 78
            },
            {
                "start_pos": 91,
                "end_pos": 93
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 5
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 5
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
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                "type",
                "subtype",
                "site_category",
                "site_seq",
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                "comment",
                "start_pos",
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        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
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                {
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                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
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                {
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