{
    "uniprot_canonical_ac": "B9A014-1",
    "uniprot_ac": "B9A014",
    "uniprot_id": "F243A_HUMAN",
    "mass": {
        "chemical_mass": 29214.0,
        "monoisotopic_mass": 29214.0
    },
    "refseq": {
        "ac": "NP_001269466",
        "name": "uncharacterized protein C21orf140",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269466"
    },
    "gene_names": [
        {
            "name": "C21orf140",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/B9A014",
            "id": "B9A014"
        },
        {
            "name": "C21orf140",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269466",
            "id": "NP_001269466"
        },
        {
            "name": "FAM243A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269466",
            "id": "NP_001269466"
        },
        {
            "name": "FAM243A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/B9A014",
            "id": "B9A014"
        }
    ],
    "protein_names": [
        {
            "name": "Uncharacterized protein C21orf140",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "B9A014"
        },
        {
            "name": "Protein FAM243A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "B9A014"
        },
        {
            "name": "protein FAM243A; family with sequence similarity 243 member A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269466",
            "id": "NP_001269466"
        },
        {
            "name": "uncharacterized protein C21orf140",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269466",
            "id": "NP_001269466"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [
        {
            "tissue": {
                "name": "Adult mammalian kidney",
                "namespace": "UBERON",
                "id": "0000082",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000082"
            },
            "score": "73.28",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Stomach",
                "namespace": "UBERON",
                "id": "0000945",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000945"
            },
            "score": "74.09",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Esophagus",
                "namespace": "UBERON",
                "id": "0001043",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043"
            },
            "score": "76.34",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Rectum",
                "namespace": "UBERON",
                "id": "0001052",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001052"
            },
            "score": "71.3",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Urinary bladder",
                "namespace": "UBERON",
                "id": "0001255",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255"
            },
            "score": "75.99",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Thyroid gland",
                "namespace": "UBERON",
                "id": "0002046",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046"
            },
            "score": "76.44",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Liver",
                "namespace": "UBERON",
                "id": "0002107",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107"
            },
            "score": "47.26",
            "present": "MEDIUM",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Prostate gland",
                "namespace": "UBERON",
                "id": "0002367",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367"
            },
            "score": "71.19",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        },
        {
            "tissue": {
                "name": "Thoracic mammary gland",
                "namespace": "UBERON",
                "id": "0005200",
                "url": "http://purl.obolibrary.org/obo/UBERON_0005200"
            },
            "score": "75.27",
            "present": "HIGH",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000222018",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018"
                }
            ]
        }
    ],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B9A014",
                    "url": "https://www.uniprot.org/uniprot/B9A014"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "C21orf140",
            "url": "https://www.uniprot.org/uniprot/B9A014",
            "locus": {
                "chromosome": "21",
                "start_pos": 34400112,
                "end_pos": 34401072,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000222018",
                        "url": "https://www.ensembl.org/id/ENSG00000222018"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000222018",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000222018",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "C21orf140",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=C21orf140",
            "database": "GeneCards",
            "categories": [
                "Gene Annotation",
                "Organism-specific"
            ]
        },
        {
            "id": "101928147",
            "url": "https://www.ncbi.nlm.nih.gov/gene/101928147",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "39602",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=39602",
            "database": "HGNC",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "B9A014",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:B9A014*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR037728",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037728",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NX_B9A014",
            "url": "https://www.nextprot.org/entry/NX_B9A014",
            "database": "neXtProt",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "NKVRRWE",
            "url": "https://omabrowser.org/oma/group/NKVRRWE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5342453at2759",
            "url": "http://www.orthodb.org/?query=5342453at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR35969",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35969",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR35969:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35969:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "B9A014",
            "url": "https://pharos.nih.gov/targets/B9A014",
            "database": "PHAROS",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "PR_B9A014",
            "url": "http://purl.obolibrary.org/obo/PR_B9A014",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001269466",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269466",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B9A014",
            "url": "https://www.uniprot.org/uniprot/B9A014",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B9A014-1",
            "url": "https://www.uniprot.org/uniprot/B9A014-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MPRFASPLLRNVIIRSQFDGIKRKQCLQYLKTLRTLQYDGFKTVYFGETNIPESLVTGEDISDGYFIQTPTWCIVHAAGSQGWVPWKYRVFLRDELCIKQEDSLFSEFCDVVRKAYGKCVIVVKERRQQEEQRPKEDREAEGQFYIPTVISLASIMCCPEVAKSCGHELLSLPSPCNYLNPLDSAWSSLKWFIINNRNEFCLQSIDSGYSYQCILFSNLISKGIERINASKWRTLTSKVRRWENYYLGKFS",
        "length": 251,
        "header": "sp|B9A014-1|F243A_HUMAN Isoform 1 of Uncharacterized protein C21orf140  OS=Homo sapiens OX=9606 GN=C21orf140 PE=2 SV=1 CANONICAL=B9A014-1"
    },
    "isoforms": [
        {
            "isoform_ac": "B9A014-1",
            "url": "",
            "sequence": {
                "sequence": "MPRFASPLLRNVIIRSQFDGIKRKQCLQYLKTLRTLQYDGFKTVYFGETNIPESLVTGEDISDGYFIQTPTWCIVHAAGSQGWVPWKYRVFLRDELCIKQEDSLFSEFCDVVRKAYGKCVIVVKERRQQEEQRPKEDREAEGQFYIPTVISLASIMCCPEVAKSCGHELLSLPSPCNYLNPLDSAWSSLKWFIINNRNEFCLQSIDSGYSYQCILFSNLISKGIERINASKWRTLTSKVRRWENYYLGKFS",
                "length": 251,
                "header": "sp|B9A014-1|F243A_HUMAN Isoform 1 of Uncharacterized protein C21orf140  OS=Homo sapiens OX=9606 GN=C21orf140 PE=2 SV=1 CANONICAL=B9A014-1"
            },
            "locus": {
                "chromosome": "21",
                "start_pos": 34401072,
                "end_pos": 34400320,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000410005.2",
                        "url": "https://www.ensembl.org/id/ENST00000410005.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000386791.1",
                        "url": "https://www.ensembl.org/id/ENSP00000386791.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A6JLJ4-1",
            "protein_name": "Family with sequence similarity 243 member A",
            "gene_name": "C11h21orf140",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MARFTNCLLKDIIIRSQFDSTKRRQCLQYLNALRSLQRNGYKTVYFGETEIPETLVTGEDFSDNGYMHTPSWCILHAGGSQGWVPWKYRMFLKDDLHIKQEDGLFFEFCDIAKRAYGKCAIVVKGRRQQDETKLKTSKGEEGQAYIPRSINLTSIVCSPGVAKSYGHELISLPLPYNYLNPLDSAWSFVKWFIINNRKEFCLKSVDNVYTYQYILFSDLITKGIEKVNLTKWKALTNKVRRWENYYLGKFS",
                "length": 251
            },
            "evidence": [
                {
                    "id": "45933096",
                    "url": "http://www.informatics.jax.org/homology/45933096",
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            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q8CDS7-1",
            "protein_name": "Uncharacterized protein C21orf140 homolog",
            "gene_name": "Fam243",
            "tax_id": 10090,
            "organism": "Mus musculus",
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                "length": 251
            },
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                {
                    "id": "B9A014",
                    "url": "https://omabrowser.org/oma/group/B9A014/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {},
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 228,
            "end_pos": 230,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 228,
                "end_pos": 230
            }
        ]
    },
    "section_stats": [
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}