{
    "uniprot_canonical_ac": "B0G130-1",
    "uniprot_ac": "B0G130",
    "uniprot_id": "B0G130_DICDI",
    "mass": {
        "chemical_mass": 74826.0,
        "monoisotopic_mass": 74826.0
    },
    "refseq": {
        "ac": "XP_001732993",
        "name": "HAM group protein",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001732993"
    },
    "gene_names": [
        {
            "name": "DDB_G0279699",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/B0G130",
            "id": "B0G130"
        }
    ],
    "protein_names": [
        {
            "name": "Histone acetyltransferase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "B0G130"
        },
        {
            "name": "2.3.1.48",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "B0G130"
        },
        {
            "name": "HAM group protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001732993",
            "id": "XP_001732993"
        },
        {
            "name": "MOZ/SAS-like domain-containing protein; MYST family protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001732993",
            "id": "XP_001732993"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Dictyostelium discoideum",
            "taxid": 44689,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B0G130",
                    "url": "https://www.uniprot.org/uniprot/B0G130"
                }
            ],
            "common_name": "Cellular slime molds"
        }
    ],
    "gene": [
        {
            "name": "",
            "url": "https://www.uniprot.org/uniprot/B0G130",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "DDB_G0279699",
            "url": "http://dictybase.org/gene/DDB_G0279699",
            "database": "dictyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "8622183",
            "url": "https://www.ncbi.nlm.nih.gov/gene/8622183",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR002717",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002717",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016181",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016197",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR025995",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR025995",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036388",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR040706",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040706",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ddi:DDB_G0279699",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0279699",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "PTHR10615",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10615",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10615:SF161",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10615:SF161",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01853",
            "url": "http://pfam.xfam.org/family/PF01853",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF11717",
            "url": "http://pfam.xfam.org/family/PF11717",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF17772",
            "url": "http://pfam.xfam.org/family/PF17772",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-2559586",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-2559586",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-3214847",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-3214847",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-5693548",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693548",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-5693565",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693565",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-6804758",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-6804758",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DDI-9018519",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9018519",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_001732993",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001732993",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "45948",
            "url": "https://www.rhea-db.org/rhea/45948",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "B0G130",
            "url": "https://www.uniprot.org/uniprot/B0G130",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B0G130-1",
            "url": "https://www.uniprot.org/uniprot/B0G130-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MTNSDENTIKPDNSVDNNNSNSKNSTDIEFLESKSDDNNDQISETIKKIENNDANNDDKENIKVNDANNDEKEEKEKQKEKEKEKEKENIVNETITTETIQITDTKKIKEPIIITTTTATATTTIESIAVIKNDIEEDTSEKPTKKLKETPINTDEESKTSQKISSITSAPTPTPTTPLTKSSEPAPQPTTSTTASTTTAATTTNNNNNNNNNYNNNNNNNNNNNNNNRKVLENGTNIYCFWRNKFQKCEIIDKREAESESGTFDYYVHYHSSNRRMDEWVHESRLDFNRLETDSGGGSGGGSGSGGGGGNGSGTDGHLHHQKSSGQLAEIQTDGHSRKVTRQIKRKYEEMNHIQKGIDEDHSKLSAIEKEHEEITKVKNINVIELGKFEIDTWYFSPYPEEFAKCDKLFLCEFCLKYMKKKKTLNRHKLKCDLRHPPGNEIYRSGNISMFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYIMTECDQRGCHMVGYFSKEKDSPDGYNLACILTLPPYQRKGFGKLLISFSYELSKKESKVGTPEKPLSDLGLLSFRSYWTQVLLEILRKHKGNLSILDISNMTSIRTEDVISTLQSLNLIRYWKGQHIISVTPKAIEEHLKVYSKQTTRIDPKCIHWAPLNPPTTTKKR",
        "length": 657,
        "header": "tr|B0G130-1|B0G130_DICDI Isoform 1 of Histone acetyltransferase  OS=Dictyostelium discoideum OX=44689 GN= PE=3 SV=1 CANONICAL=B0G130-1"
    },
    "isoforms": [
        {
            "isoform_ac": "B0G130-1",
            "url": "",
            "sequence": {
                "sequence": "MTNSDENTIKPDNSVDNNNSNSKNSTDIEFLESKSDDNNDQISETIKKIENNDANNDDKENIKVNDANNDEKEEKEKQKEKEKEKEKENIVNETITTETIQITDTKKIKEPIIITTTTATATTTIESIAVIKNDIEEDTSEKPTKKLKETPINTDEESKTSQKISSITSAPTPTPTTPLTKSSEPAPQPTTSTTASTTTAATTTNNNNNNNNNYNNNNNNNNNNNNNNRKVLENGTNIYCFWRNKFQKCEIIDKREAESESGTFDYYVHYHSSNRRMDEWVHESRLDFNRLETDSGGGSGGGSGSGGGGGNGSGTDGHLHHQKSSGQLAEIQTDGHSRKVTRQIKRKYEEMNHIQKGIDEDHSKLSAIEKEHEEITKVKNINVIELGKFEIDTWYFSPYPEEFAKCDKLFLCEFCLKYMKKKKTLNRHKLKCDLRHPPGNEIYRSGNISMFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYIMTECDQRGCHMVGYFSKEKDSPDGYNLACILTLPPYQRKGFGKLLISFSYELSKKESKVGTPEKPLSDLGLLSFRSYWTQVLLEILRKHKGNLSILDISNMTSIRTEDVISTLQSLNLIRYWKGQHIISVTPKAIEEHLKVYSKQTTRIDPKCIHWAPLNPPTTTKKR",
                "length": 657,
                "header": "tr|B0G130-1|B0G130_DICDI Isoform 1 of Histone acetyltransferase  OS=Dictyostelium discoideum OX=44689 GN= PE=3 SV=1 CANONICAL=B0G130-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "The genome of the social amoeba Dictyostelium discoideum.",
            "journal": "Nature",
            "date": "2005",
            "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B0G130",
                    "url": "https://www.uniprot.org/uniprot/B0G130"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15875012",
                    "url": "https://glygen.org/publication/PubMed/15875012"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "ddi:DDB_G0279699",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0279699",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DDI-2559586",
            "name": "DNA Damage/Telomere Stress Induced Senescence",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-2559586",
            "resource": "Reactome",
            "description": "DNA Damage/Telomere Stress Induced Senescence"
        },
        {
            "id": "R-DDI-3214847",
            "name": "HATs acetylate histones",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-3214847",
            "resource": "Reactome",
            "description": "HATs acetylate histones"
        },
        {
            "id": "R-DDI-5693548",
            "name": "Sensing of DNA Double Strand Breaks",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693548",
            "resource": "Reactome",
            "description": "Sensing of DNA Double Strand Breaks"
        },
        {
            "id": "R-DDI-5693565",
            "name": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693565",
            "resource": "Reactome",
            "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
        },
        {
            "id": "R-DDI-6804758",
            "name": "Regulation of TP53 Activity through Acetylation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-6804758",
            "resource": "Reactome",
            "description": "Regulation of TP53 Activity through Acetylation"
        },
        {
            "id": "R-DDI-9018519",
            "name": "Estrogen-dependent gene expression",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9018519",
            "resource": "Reactome",
            "description": "Estrogen-dependent gene expression"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B0G130",
                                "url": "https://www.uniprot.org/uniprot/B0G130"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "positive regulation of transcription by RNA polymerase II",
                        "id": "GO:0045944",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B0G130",
                                "url": "https://www.uniprot.org/uniprot/B0G130"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of DNA-templated transcription",
                        "id": "GO:0045892",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B0G130",
                                "url": "https://www.uniprot.org/uniprot/B0G130"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "transcription coregulator activity",
                        "id": "GO:0003712",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B0G130",
                                "url": "https://www.uniprot.org/uniprot/B0G130"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone acetyltransferase activity",
                        "id": "GO:0004402",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B0G130",
                                "url": "https://www.uniprot.org/uniprot/B0G130"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 18,
            "end_pos": 20,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 234,
            "end_pos": 236,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 24,
            "end_pos": 26,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 311,
            "end_pos": 313,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 447,
            "end_pos": 449,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 581,
            "end_pos": 583,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 589,
            "end_pos": 591,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 92,
            "end_pos": 94,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "45948",
            "name": "",
            "equation": "acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-lysyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q6JHU9-1",
                "Q9WVS9-1",
                "Q9EPU2-1",
                "Q9QXS4-1",
                "Q3MHC1-1",
                "Q5TKR9-1",
                "Q5XI06-1",
                "P62916-1",
                "Q5M939-1",
                "A0A8I6GLZ3-1",
                "D4ACX5-1",
                "Q99MK2-1",
                "Q00972-1",
                "A0A8I5Y222-1",
                "Q6DGG1-1",
                "Q92793-1",
                "Q9Y6F8-1",
                "O15516-1",
                "Q9H7Z6-1",
                "Q9Y6F7-1",
                "Q56NI9-1",
                "Q5FWF5-1",
                "Q09472-1",
                "O14929-1",
                "Q92831-1",
                "Q8WYB5-1",
                "Q92794-1",
                "Q92830-1",
                "Q15788-1",
                "Q9Y6Q9-1",
                "Q9H7X0-1",
                "Q9UKN8-1",
                "Q92993-1",
                "Q00403-1",
                "P21675-2",
                "Q96IU4-1",
                "Q9JIY8-1",
                "Q9DBU2-1",
                "O08785-1",
                "P45481-1",
                "Q9WTK2-1",
                "Q8CIB9-1",
                "B2RWS6-1",
                "Q69Z69-1",
                "Q8CHK4-1",
                "Q9JHD2-1",
                "Q8BY71-1",
                "Q8BZ21-1",
                "Q8BRB7-1",
                "Q5SVQ0-1",
                "Q9JHD1-1",
                "Q9D1P2-1",
                "P70365-1",
                "O09000-1",
                "P62915-1",
                "Q8BMQ2-1",
                "Q80UV9-1",
                "E0CYR6-1",
                "Q8VCR7-1",
                "P46677-1",
                "Q07794-1",
                "Q08649-1",
                "P39979-1",
                "Q06592-1",
                "Q12341-1",
                "P34218-1",
                "P40963-1",
                "Q03330-1",
                "B0G130-1",
                "Q869X7-1",
                "Q86J12-1",
                "Q869X5-1",
                "Q960X4-1",
                "Q95SX8-1",
                "Q9W1A9-1",
                "O02193-1",
                "Q0KIB3-1",
                "Q9VAV6-1"
            ],
            "evidence": [
                {
                    "id": "45948",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/45948"
                }
            ]
        },
        {
            "id": "R-DDI-3318413",
            "name": "KAT7-containing ING4/5 complexes acetylate Me3K-histone H3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [
                "R-DDI-1214186"
            ],
            "output_participant_list": [
                "R-DDI-4551293"
            ],
            "enzyme_list": [
                "B0G130-1",
                "Q869X5-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-3318413",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-3318413"
                }
            ]
        },
        {
            "id": "R-DDI-3318486",
            "name": "KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q869X5-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-3318486",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-3318486"
                }
            ]
        },
        {
            "id": "R-DDI-5682026",
            "name": "MRN bound to shortened telomeres activates ATM",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [
                "R-DDI-5693527"
            ],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5682026",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5682026"
                }
            ]
        },
        {
            "id": "R-DDI-5682044",
            "name": "KAT5 acetylates ATM at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5682044",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5682044"
                }
            ]
        },
        {
            "id": "R-DDI-5682588",
            "name": "RNF8 binds phosphorylated MDC1 at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5682588",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5682588"
                }
            ]
        },
        {
            "id": "R-DDI-5682965",
            "name": "WHSC1 dimethylates histone H4 on lysine K21 at DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5682965",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5682965"
                }
            ]
        },
        {
            "id": "R-DDI-5682967",
            "name": "WHSC1 binds DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5682967",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5682967"
                }
            ]
        },
        {
            "id": "R-DDI-5682983",
            "name": "ATM phosphorylates WHSC1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5682983",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5682983"
                }
            ]
        },
        {
            "id": "R-DDI-5683405",
            "name": "PPP5C dephosphorylates TP53BP1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q54RH6-1",
                "B0G130-1",
                "Q54ER4-1",
                "Q86K32-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5683405",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5683405"
                }
            ]
        },
        {
            "id": "R-DDI-5683425",
            "name": "ATM phosphorylates TP53BP1 at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q86K32-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5683425",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5683425"
                }
            ]
        },
        {
            "id": "R-DDI-5693536",
            "name": "ATM phosphorylates MDC1",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5693536",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693536"
                }
            ]
        },
        {
            "id": "R-DDI-5693540",
            "name": "MRN activates ATM",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5693540",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693540"
                }
            ]
        },
        {
            "id": "R-DDI-5693549",
            "name": "ATM phosphorylates histone H2AFX on S139 at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5693549",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693549"
                }
            ]
        },
        {
            "id": "R-DDI-5693566",
            "name": "TP53BP1 associates with H4K20Me2 at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q86K32-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5693566",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693566"
                }
            ]
        },
        {
            "id": "R-DDI-5693598",
            "name": "ATM phosphorylates NBN",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5693598",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693598"
                }
            ]
        },
        {
            "id": "R-DDI-5693602",
            "name": "ATM recognizes H2AFX-Nucleosomes",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-5693602",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-5693602"
                }
            ]
        },
        {
            "id": "R-DDI-6792712",
            "name": "KAT5 acetylates ATM at shortened telomeres",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54ER4-1",
                "Q54CS9-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-6792712",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-6792712"
                }
            ]
        },
        {
            "id": "R-DDI-6805640",
            "name": "AKT phosphorylates KAT6A",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "B0G130-1",
                "Q54IF2-1",
                "Q869X5-1",
                "P54644-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-6805640",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-6805640"
                }
            ]
        },
        {
            "id": "R-DDI-9023860",
            "name": "Histone acetyltransferases are recruited to the TFF1 gene",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q54R05-1",
                "B0G130-1",
                "Q54CE0-1",
                "Q54EF2-1",
                "Q54HI0-1"
            ],
            "evidence": [
                {
                    "id": "R-DDI-9023860",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-DDI-9023860"
                }
            ]
        }
    ],
    "reaction_participants": [
        {
            "participant_id": "R-DDI-1214186",
            "participant_name": "H3a [nucleoplasm]",
            "crossref": [
                {
                    "id": "O15819",
                    "database": "UniProt",
                    "url": ""
                },
                {
                    "id": "O15819",
                    "database": "PRO",
                    "url": ""
                },
                {
                    "id": "XP_647577.1",
                    "database": "RefSeq",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-DDI-4551293",
            "participant_name": "H3a [nucleoplasm]",
            "crossref": [
                {
                    "id": "O15819",
                    "database": "UniProt",
                    "url": ""
                },
                {
                    "id": "XP_647577.1",
                    "database": "RefSeq",
                    "url": ""
                },
                {
                    "id": "O15819",
                    "database": "PRO",
                    "url": ""
                }
            ]
        },
        {
            "participant_id": "R-DDI-5693527",
            "participant_name": "phospho-atr1 [nucleoplasm]",
            "crossref": [
                {
                    "id": "Q54ER4",
                    "database": "UniProt",
                    "url": ""
                },
                {
                    "id": "Q54ER4",
                    "database": "PRO",
                    "url": ""
                },
                {
                    "id": "XP_635176.1",
                    "database": "RefSeq",
                    "url": ""
                }
            ]
        }
    ],
    "reaction_enzymes": [
        {
            "uniprot_ac": "A0A8I5Y222",
            "gene_name": "Kat2b",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "A0A8I5Y222",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5Y222"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5Y222",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5Y222"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6GLZ3",
            "gene_name": "Kat6b",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "A0A8I6GLZ3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GLZ3"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6GLZ3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GLZ3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B0G130",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "B0G130",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B0G130"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B0G130",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B0G130"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B2RWS6",
            "gene_name": "Ep300",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "B2RWS6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RWS6"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B2RWS6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RWS6"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B2RWS6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RWS6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4ACX5",
            "gene_name": "Kat2a",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "D4ACX5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ACX5"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4ACX5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ACX5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E0CYR6",
            "gene_name": "Nat8f7",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "E0CYR6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E0CYR6"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "E0CYR6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E0CYR6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O02193",
            "gene_name": "mof",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "O02193",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O02193"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O02193",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O02193"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08785",
            "gene_name": "Clock",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "O08785",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08785"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08785",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08785"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09000",
            "gene_name": "Ncoa3",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "O09000",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09000"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09000",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09000"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O14929",
            "gene_name": "HAT1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "O14929",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14929"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O14929",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14929"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O15516",
            "gene_name": "CLOCK",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "O15516",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15516"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O15516",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15516"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P21675",
            "gene_name": "TAF1",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P21675",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21675"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P21675",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21675"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21675",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21675"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P21675",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P21675"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P34218",
            "gene_name": "SAS3",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P34218",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34218"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P34218",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P34218"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P39979",
            "gene_name": "HPA3",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P39979",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P39979"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.36",
                    "activity": "a D-alpha-amino acid + acetyl-CoA = an N-acetyl-D-amino acid + CoA + H(+).",
                    "evidence": [
                        {
                            "id": "P39979",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P39979"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.36",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P39979",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P39979"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P39979",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P39979"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P40963",
            "gene_name": "SAS2",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P40963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P40963"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P40963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P40963"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P45481",
            "gene_name": "Crebbp",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P45481",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P45481"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P45481",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P45481"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P45481",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P45481"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P46677",
            "gene_name": "TAF1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P46677",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P46677"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P46677",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P46677"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P54644",
            "gene_name": "pkbA",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P54644",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54644"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P54644",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54644"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P62915",
            "gene_name": "Gtf2b",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P62915",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P62915"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P62915",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P62915"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P62916",
            "gene_name": "Gtf2b",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P62916",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P62916"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P62916",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P62916"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70365",
            "gene_name": "Ncoa1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "P70365",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70365"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70365",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70365"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00403",
            "gene_name": "GTF2B",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q00403",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00403"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00403",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00403"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00972",
            "gene_name": "Bckdk",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00972",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00972"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.4",
                    "activity": "ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].",
                    "evidence": [
                        {
                            "id": "Q00972",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00972"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00972",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00972"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q00972",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00972"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00972",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00972"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03330",
            "gene_name": "GCN5",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q03330",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03330"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03330",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03330"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03330",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03330"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06592",
            "gene_name": "HPA2",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q06592",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06592"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q06592",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06592"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q07794",
            "gene_name": "RTT109",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q07794",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07794"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07794",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07794"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q08649",
            "gene_name": "ESA1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q08649",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08649"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q08649",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08649"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q08649",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08649"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q09472",
            "gene_name": "EP300",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q09472",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09472"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q09472",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09472"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q09472",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09472"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q0KIB3",
            "gene_name": "Hat1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q0KIB3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q0KIB3"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q0KIB3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q0KIB3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q12341",
            "gene_name": "HAT1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q12341",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q12341"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q12341",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q12341"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q15788",
            "gene_name": "NCOA1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q15788",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15788"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q15788",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q15788"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q3MHC1",
            "gene_name": "Naa60",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q3MHC1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHC1"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q3MHC1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHC1"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein].",
                    "evidence": [
                        {
                            "id": "Q3MHC1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHC1"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q3MHC1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHC1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54CE0",
            "gene_name": "ddx17",
            "activity": [
                {
                    "ec_number": "3.6.4.13",
                    "activity": "ATP + H2O = ADP + H(+) + phosphate.",
                    "evidence": [
                        {
                            "id": "Q54CE0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54CE0"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.4.13",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54CE0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54CE0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54CS9",
            "gene_name": "rad50",
            "activity": [
                {
                    "ec_number": "3.6.-.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54CS9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54CS9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54EF2",
            "gene_name": "prmt1",
            "activity": [
                {
                    "ec_number": "2.1.1.319",
                    "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine.",
                    "evidence": [
                        {
                            "id": "Q54EF2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54EF2"
                        }
                    ]
                },
                {
                    "ec_number": "2.1.1.319",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54EF2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54EF2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54ER4",
            "gene_name": "atr1",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54ER4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54ER4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54ER4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54ER4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54HI0",
            "gene_name": "prmt2",
            "activity": [
                {
                    "ec_number": "2.1.1.319",
                    "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine.",
                    "evidence": [
                        {
                            "id": "Q54HI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54HI0"
                        }
                    ]
                },
                {
                    "ec_number": "2.1.1.319",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54HI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54HI0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54IF2",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q54IF2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54IF2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54IF2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54IF2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54R05",
            "gene_name": "gcn5",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q54R05",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54R05"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54R05",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54R05"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q54RH6",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "3.1.3.16",
                    "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.",
                    "evidence": [
                        {
                            "id": "Q54RH6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54RH6"
                        }
                    ]
                },
                {
                    "ec_number": "3.1.3.16",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q54RH6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54RH6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q56NI9",
            "gene_name": "ESCO2",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q56NI9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q56NI9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5FWF5",
            "gene_name": "ESCO1",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5FWF5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5FWF5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5M939",
            "gene_name": "Hat1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q5M939",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5M939"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5M939",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5M939"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5SVQ0",
            "gene_name": "Kat7",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q5SVQ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5SVQ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5SVQ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5SVQ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5TKR9",
            "gene_name": "Kat6a",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q5TKR9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5TKR9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5TKR9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5TKR9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5XI06",
            "gene_name": "Kat8",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q5XI06",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5XI06"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5XI06",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5XI06"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q69Z69",
            "gene_name": "Esco1",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q69Z69",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q69Z69"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6DGG1",
            "gene_name": "Abhd14b",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6DGG1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6DGG1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6JHU9",
            "gene_name": "Crebbp",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q6JHU9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6JHU9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6JHU9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6JHU9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6JHU9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6JHU9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q80UV9",
            "gene_name": "Taf1",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q80UV9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q80UV9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q80UV9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q80UV9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q80UV9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q80UV9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q80UV9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q80UV9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q869X5",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q869X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q869X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q869X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q869X5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q869X7",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q869X7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q869X7"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q869X7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q869X7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q86J12",
            "gene_name": "",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q86J12",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q86J12"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q86J12",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q86J12"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q86K32",
            "gene_name": "ube2n",
            "activity": [
                {
                    "ec_number": "2.3.2.23",
                    "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.",
                    "evidence": [
                        {
                            "id": "Q86K32",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q86K32"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q86K32",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q86K32"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BMQ2",
            "gene_name": "Gtf3c4",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q8BMQ2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BMQ2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BMQ2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BMQ2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BRB7",
            "gene_name": "Kat6b",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q8BRB7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BRB7"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BRB7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BRB7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BY71",
            "gene_name": "Hat1",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q8BY71",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BY71"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BY71",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BY71"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8BZ21",
            "gene_name": "Kat6a",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q8BZ21",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BZ21"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8BZ21",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8BZ21"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8CHK4",
            "gene_name": "Kat5",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q8CHK4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CHK4"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8CHK4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CHK4"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8CHK4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CHK4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8CIB9",
            "gene_name": "Esco2",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8CIB9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CIB9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8VCR7",
            "gene_name": "Abhd14b",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8VCR7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VCR7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8WYB5",
            "gene_name": "KAT6B",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q8WYB5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8WYB5"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8WYB5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8WYB5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q92793",
            "gene_name": "CREBBP",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q92793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92793"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92793"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92793"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q92794",
            "gene_name": "KAT6A",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q92794",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92794"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92794",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92794"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q92830",
            "gene_name": "KAT2A",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q92830",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92830"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92830",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92830"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92830",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92830"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q92831",
            "gene_name": "KAT2B",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q92831",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92831"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.57",
                    "activity": "acetyl-CoA + an alkane-alpha,omega-diamine = an N-acetylalkane-alpha,omega-diamine + CoA + H(+).",
                    "evidence": [
                        {
                            "id": "Q92831",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92831"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92831",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92831"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q92993",
            "gene_name": "KAT5",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q92993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92993"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92993"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q92993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q92993"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q95SX8",
            "gene_name": "Naa60",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q95SX8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q95SX8"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein].",
                    "evidence": [
                        {
                            "id": "Q95SX8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q95SX8"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q95SX8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q95SX8"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q95SX8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q95SX8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q960X4",
            "gene_name": "Tip60",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q960X4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q960X4"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q960X4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q960X4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q96IU4",
            "gene_name": "ABHD14B",
            "activity": [
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q96IU4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q96IU4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q99MK2",
            "gene_name": "Kat5",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q99MK2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99MK2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q99MK2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99MK2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q99MK2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99MK2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9D1P2",
            "gene_name": "Kat8",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9D1P2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9D1P2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9D1P2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9D1P2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9DBU2",
            "gene_name": "Naa60",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9DBU2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9DBU2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein].",
                    "evidence": [
                        {
                            "id": "Q9DBU2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9DBU2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9DBU2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9DBU2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9DBU2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9DBU2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9EPU2",
            "gene_name": "Ncoa3",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9EPU2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9EPU2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9EPU2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9EPU2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9H7X0",
            "gene_name": "NAA60",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9H7X0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H7X0"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein].",
                    "evidence": [
                        {
                            "id": "Q9H7X0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H7X0"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9H7X0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H7X0"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.259",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9H7X0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H7X0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9H7Z6",
            "gene_name": "KAT8",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9H7Z6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H7Z6"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9H7Z6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H7Z6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JHD1",
            "gene_name": "Kat2b",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9JHD1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JHD1"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.57",
                    "activity": "acetyl-CoA + an alkane-alpha,omega-diamine = an N-acetylalkane-alpha,omega-diamine + CoA + H(+).",
                    "evidence": [
                        {
                            "id": "Q9JHD1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JHD1"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9JHD1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JHD1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JHD2",
            "gene_name": "Kat2a",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q9JHD2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JHD2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9JHD2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JHD2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9JHD2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JHD2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JIY8",
            "gene_name": "Nat8f3",
            "activity": [
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                    "ec_number": "2.3.1.48",
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