{ "uniprot_canonical_ac": "A3QJZ6-1", "uniprot_ac": "A3QJZ6", "uniprot_id": "PRA22_HUMAN", "mass": { "chemical_mass": 55489.0, "monoisotopic_mass": 55489.0 }, "refseq": { "ac": "NP_001094101", "name": "PRAME family member 22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094101" }, "gene_names": [ { "name": "PRAMEF22", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A3QJZ6", "id": "A3QJZ6" }, { "name": "PRAMEF22", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094101", "id": "NP_001094101" }, { "name": "PRAMEF3L", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094101", "id": "NP_001094101" } ], "protein_names": [ { "name": "PRAME family member 22", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A3QJZ6" }, { "name": "PRAME family member 22", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094101", "id": "NP_001094101" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6" } ], "common_name": "Human" } ], "gene": [ { "name": "PRAMEF22", "url": "https://www.uniprot.org/uniprot/A3QJZ6", "locus": {} } ], "crossref": [ { "id": "PRAMEF22", "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=PRAMEF22", "database": "GeneCards", "categories": [ "Gene Annotation", "Organism-specific" ] }, { "id": "653606", "url": "https://www.ncbi.nlm.nih.gov/gene/653606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "34393", "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=34393", "database": "HGNC", "categories": [ "Organism-specific" ] }, { "id": "A3QJZ6", "url": "https://www.ebi.ac.uk/intact/interactors/id:A3QJZ6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR026271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "hsa:653606", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:653606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NX_A3QJZ6", "url": "https://www.nextprot.org/entry/NX_A3QJZ6", "database": "neXtProt", "categories": [ "Protein", "Organism-specific" ] }, { "id": "PTHR14224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224:SF79", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224:SF79", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A3QJZ6", "url": "https://pharos.nih.gov/targets/A3QJZ6", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR_A3QJZ6", "url": "http://purl.obolibrary.org/obo/PR_A3QJZ6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001094101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094101", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3QJZ6-1", "url": "https://www.uniprot.org/uniprot/A3QJZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA", "length": 481, "header": "sp|A3QJZ6-1|PRA22_HUMAN Isoform 1 of PRAME family member 22 OS=Homo sapiens OX=9606 GN=PRAMEF22 PE=3 SV=3 CANONICAL=A3QJZ6-1" }, "isoforms": [ { "isoform_ac": "A3QJZ6-1", "url": "", "sequence": { "sequence": "MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA", "length": 481, "header": "sp|A3QJZ6-1|PRA22_HUMAN Isoform 1 of PRAME family member 22 OS=Homo sapiens OX=9606 GN=PRAMEF22 PE=3 SV=3 CANONICAL=A3QJZ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "hsa:653606", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:653606", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "A3QJZ7-1", "protein_name": "PRAME family member 27", "gene_name": "PRAMEF27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRCCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVCPRRWKLQVLDLQDVCENFWMVWSEAMARGSFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNAFSFCGNPISMATLENLLSHTIILKNLCVEVYPAPRESYGADGTLCWNRFAQIRAELMNRVRDLRHPKRIFFCIDNCPDCGNRSFYDLEADQYCC", "length": 478 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "A6NGN4-1", "protein_name": "PRAME family member 25", "gene_name": "PRAMEF25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMSIRTPPRLLELAGRSVLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLETFQAVLNGLDALLTHGVRPRRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC", "length": 478 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "O60809-1", "protein_name": "PRAME family member 10", "gene_name": "PRAMEF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "O60810-1", "protein_name": "PRAME family member 4", "gene_name": "PRAMEF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMKGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC", "length": 478 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "O60813-1", "protein_name": "PRAME family member 11", "gene_name": "PRAMEF11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMSIRIPPRLLELAGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC", "length": 478 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "O95521-1", "protein_name": "PRAME family member 1", "gene_name": "PRAMEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWPFTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAWALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFSRCHHYTSDNELEGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQIHYSQLSAILPGLSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "O95522-1", "protein_name": "PRAME family member 12", "gene_name": "PRAMEF12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGASALSPEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGTLDECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACCQGGFI", "length": 483 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUQ2-1", "protein_name": "PRAME family member 9", "gene_name": "PRAMEF9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC", "length": 478 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "P78395-1", "protein_name": "Melanoma antigen preferentially expressed in tumors", "gene_name": "PRAME", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPILCPCFMPN", "length": 509 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SWL8-1", "protein_name": "PRAME family member 19", "gene_name": "PRAMEF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRCCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFISDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA", "length": 479 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5TYX0-1", "protein_name": "PRAME family member 5", "gene_name": "PRAMEF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC", "length": 476 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VT98-1", "protein_name": "PRAME family member 20", "gene_name": "PRAMEF20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPLQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLSDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC", "length": 475 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VTA0-1", "protein_name": "PRAME family member 17", "gene_name": "PRAMEF17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGARALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VWM3-1", "protein_name": "PRAME family member 18", "gene_name": "PRAMEF18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGARLLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWLCMIVEFSRYLSQMRNLRKLFISDGCRYLLSSDSQEQLVAEFSSVLLRLENLQMLYVRRVCFFRGHLDQLIRCLRSPLETLALTYGFLEEEDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDALKDLLRHTGRLSNLSLETYPAPRESLDNRGRVILELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLESNFCLWGRPA", "length": 479 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VWM4-1", "protein_name": "PRAME family member 8", "gene_name": "PRAMEF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGATASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMNTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VWM6-1", "protein_name": "Putative PRAME family member 13", "gene_name": "PRAMEF13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRRKLQVLDLRDVDENFWARWPGAWALSCFPETMSKRQTAEDRPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQELEIHNMSWPRLIRKLRCYLKEMKTLGKLVFSRCHHSTSDNELEGRLVTKFSSVFLGLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLELTYGYLLEEDVKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQIHYSQLSAILPGLSRCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSLSEELELHLCC", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VXH4-1", "protein_name": "PRAME family member 6", "gene_name": "PRAMEF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC", "length": 476 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VXH5-1", "protein_name": "PRAME family member 7", "gene_name": "PRAMEF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGATASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQAVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMNTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC", "length": 474 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2F1-1", "protein_name": "PRAME like 13", "gene_name": "Pramel13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLRATPTLLQLAMQSLLRDEALAISALQDLPMELLPPLFKDAITHKRLNILRKMVQVWPFPCLPLGGLMKMKTPYLDILQTVLDGVDALLDQNTHPRNYKLQVLDLRALHKDFWTVWAGDTTTSCAPGVKCRRKIQKRGPKIEAKQNSLKVFIDLYLKPRALDTCLSYVFLWARERKALLQLGCKKLKINTVAIQNIVKILEMLDLDYVEEVEVCCTWKLSTLAIFAPYLGQMKNLLSIILSHIHVPASITPEEEKQLVSQFTSQFSNLQYLQDLSLDSIDFLKGQMDQLFRCLEVPLEILSITDSKISESDLQSLSQCPGIRQLKHLNLSGVILTDISPEPLRVLLERVAATLKTLDLENCMIMDSQLDVLLPALSQCAQLIMFNYLRNPISVSILERLLHHTSGLNYLSLEMYSTPWEIYGAQGASYHKRLEQLREELSKAMQHLEHNRTVWFSVAPCLP", "length": 463 }, "evidence": [ { "id": "45935811", "url": "http://www.informatics.jax.org/homology/45935811", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A3QJZ6", "url": "https://www.uniprot.org/uniprot/A3QJZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 408, "end_pos": 410 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }