{ "uniprot_canonical_ac": "A1XDC0-1", "uniprot_ac": "A1XDC0", "uniprot_id": "TFP11_DICDI", "mass": { "chemical_mass": 103525.0, "monoisotopic_mass": 103525.0 }, "refseq": { "ac": "XP_644376", "name": "D111/G-patch domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644376" }, "gene_names": [ { "name": "stip-1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A1XDC0", "id": "A1XDC0" }, { "name": "stip-2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A1XDC0", "id": "A1XDC0" }, { "name": "DDB_G0272608", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A1XDC0", "id": "A1XDC0" }, { "name": "DDB_G0274035", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A1XDC0", "id": "A1XDC0" }, { "name": "stip-2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644376", "id": "XP_644376" }, { "name": "stip", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A1XDC0", "id": "A1XDC0" } ], "protein_names": [ { "name": "Septin and tuftelin-interacting protein 1 homolog", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A1XDC0" }, { "name": "D111/G-patch domain-containing protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644376", "id": "XP_644376" }, { "name": "STIP-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A1XDC0" } ], "function": [ { "annotation": "May be involved in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "common_name": "Cellular slime molds" } ], "gene": [ { "name": "stip-2", "url": "https://www.uniprot.org/uniprot/A1XDC0", "locus": {} } ], "crossref": [ { "id": "DDB_G0272608", "url": "http://dictybase.org/gene/DDB_G0272608", "database": "dictyBase", "categories": [ "Organism-specific" ] }, { "id": "DDB_G0274035", "url": "http://dictybase.org/gene/DDB_G0274035", "database": "dictyBase", "categories": [ "Organism-specific" ] }, { "id": "8618714", "url": "https://www.ncbi.nlm.nih.gov/gene/8618714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8619262", "url": "https://www.ncbi.nlm.nih.gov/gene/8619262", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ddi:DDB_G0272608", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0272608", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ddi:DDB_G0274035", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0274035", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEQDIIQ", "url": "https://omabrowser.org/oma/group/CEQDIIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23329:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23329:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "http://pfam.xfam.org/family/PF01585", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07842", "url": "http://pfam.xfam.org/family/PF07842", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12457", "url": "http://pfam.xfam.org/family/PF12457", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_A1XDC0", "url": "http://purl.obolibrary.org/obo/PR_A1XDC0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_644376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1XDC0-1", "url": "https://www.uniprot.org/uniprot/A1XDC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIEGDDEEFYNFNDIKKKRKFTKEDAIYGVFNDGWGDYEDEEESKMTEEEYYKMKKRYSTPVGFVASGIYEPNEHKLKNKDGENIDNDDDDGEEKKKKKKEKKEKKQKKKEKKEKKEKKNKKKNKYGGGGGNNYDDSDNDKSIEDKPVGGIGAALLSKMGYKGTGGLGRDGGGMVEPIKVQVRPKNAGLASVTELNVNSSDDSDDSDQSEGDTDSDNENKRSLGWKKKEPKLKYDFDEHLESTTTTTFKKKTTTTTATTTTSSTPQIVIDMRGPEARLYTGMEEIKHHKHHHHHQHNKEYQNITSILDDQSKPLSELKHNVDLLLKLKQIDIQNQDNKIKHENDKINNLTRGVEKLKLTIENDKEQIKKVTEILETITTVKKQLDQSQLDLKQLYKVFKKLKSNYPKEYQNFKLYNLQKELLEPLLKEKLNQWELESNSDNNDNSSLEISKKLSKEMVKWRQLFQESVSVLGEYQINVYFLIMRDLFLPKFKNYLRSQWDVKKPSNAATLISTWSDTLPDVIQEALLEQSILPKLKVAIEKWDPRTDPIPLDHWLLPWIPLLGSELESFYPLIRQKIISALQDWHPSDKSAIKILTPWKNIFQSNSMDSLLNRAIIPKLSKSIKDLEINPSNQKSPIEIQWLLRWSNLNNNDNNNNNNNNNNNDNNNNNNSITTTDNINLDSGLITLSTIICILEKDFFTRWLKILLEWLKSPDANLEEISNWYSGWKKQFPKEIISNDKIKSIFNISLNLMKKVLSNETIQKDDEILISQKINSLLNTNINNNNNNNNNINNSYQQQNQQQPIKPISSPSLNSSNNNNIDNISTKQMVEQLAIKNGLLFIPSEKKTNSGQQIYIFDKIPIIIERDLIMYNNNNNNRWEPANIQYLLDKSLNK", "length": 894, "header": "sp|A1XDC0-1|TFP11_DICDI Isoform 1 of Septin and tuftelin-interacting protein 1 homolog OS=Dictyostelium discoideum OX=44689 GN=stip-2 PE=2 SV=1 CANONICAL=A1XDC0-1" }, "isoforms": [ { "isoform_ac": "A1XDC0-1", "url": "", "sequence": { "sequence": "MNIEGDDEEFYNFNDIKKKRKFTKEDAIYGVFNDGWGDYEDEEESKMTEEEYYKMKKRYSTPVGFVASGIYEPNEHKLKNKDGENIDNDDDDGEEKKKKKKEKKEKKQKKKEKKEKKEKKNKKKNKYGGGGGNNYDDSDNDKSIEDKPVGGIGAALLSKMGYKGTGGLGRDGGGMVEPIKVQVRPKNAGLASVTELNVNSSDDSDDSDQSEGDTDSDNENKRSLGWKKKEPKLKYDFDEHLESTTTTTFKKKTTTTTATTTTSSTPQIVIDMRGPEARLYTGMEEIKHHKHHHHHQHNKEYQNITSILDDQSKPLSELKHNVDLLLKLKQIDIQNQDNKIKHENDKINNLTRGVEKLKLTIENDKEQIKKVTEILETITTVKKQLDQSQLDLKQLYKVFKKLKSNYPKEYQNFKLYNLQKELLEPLLKEKLNQWELESNSDNNDNSSLEISKKLSKEMVKWRQLFQESVSVLGEYQINVYFLIMRDLFLPKFKNYLRSQWDVKKPSNAATLISTWSDTLPDVIQEALLEQSILPKLKVAIEKWDPRTDPIPLDHWLLPWIPLLGSELESFYPLIRQKIISALQDWHPSDKSAIKILTPWKNIFQSNSMDSLLNRAIIPKLSKSIKDLEINPSNQKSPIEIQWLLRWSNLNNNDNNNNNNNNNNNDNNNNNNSITTTDNINLDSGLITLSTIICILEKDFFTRWLKILLEWLKSPDANLEEISNWYSGWKKQFPKEIISNDKIKSIFNISLNLMKKVLSNETIQKDDEILISQKINSLLNTNINNNNNNNNNINNSYQQQNQQQPIKPISSPSLNSSNNNNIDNISTKQMVEQLAIKNGLLFIPSEKKTNSGQQIYIFDKIPIIIERDLIMYNNNNNNRWEPANIQYLLDKSLNK", "length": 894, "header": "sp|A1XDC0-1|TFP11_DICDI Isoform 1 of Septin and tuftelin-interacting protein 1 homolog OS=Dictyostelium discoideum OX=44689 GN=stip-2 PE=2 SV=1 CANONICAL=A1XDC0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.", "journal": "Nature", "date": "2002", "authors": "Gl\u00f6ckner Gernot, Eichinger Ludwig, Szafranski Karol, Pachebat Justin A, Bankier Alan T, Dear Paul H, Lehmann R\u00fcdiger, Baumgart Cornelia, Parra Gen\u00eds, Abril Josep F, Guig\u00f3 Roderic, Kumpf Kai, Tunggal Budi, Cox Edward, Quail Michael A, Platzer Matthias, Rosenthal Andr\u00e9, Noegel Angelika A,", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "reference": [ { "type": "PubMed", "id": "12097910", "url": "https://glygen.org/publication/PubMed/12097910" } ] }, { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] }, { "title": "Characterization of STIP, a multi-domain nuclear protein, highly conserved in metazoans, and essential for embryogenesis in Caenorhabditis elegans.", "journal": "Exp. Cell Res.", "date": "2007", "authors": "Ji Q, Huang CH, Peng J, Hashmi S, Ye T, Chen Y", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "reference": [ { "type": "PubMed", "id": "17289020", "url": "https://glygen.org/publication/PubMed/17289020" } ] } ], "pathway": [ { "id": "ddi:DDB_G0272608", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0272608", "resource": "KEGG Pathway" }, { "id": "ddi:DDB_G0274035", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ddi:DDB_G0274035", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "pmid": "" }, { "name": "U2-type post-mRNA release spliceosomal complex", "id": "GO:0071008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071008", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spliceosomal complex disassembly", "id": "GO:0000390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000390", "evidence": [ { "database": "UniProtKB", "id": "A1XDC0", "url": "https://www.uniprot.org/uniprot/A1XDC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 670, "end_pos": 672 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 759, "end_pos": 761 }, { "start_pos": 793, "end_pos": 795 }, { "start_pos": 814, "end_pos": 816 }, { "start_pos": 823, "end_pos": 825 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }