{
    "cls_id": "homologset.mgi.46359775",
    "date": "2024-05-07 12:12:02 EDT-0400",
    "sequences": [
        {
            "uniprot_ac": "Q80Z37-1",
            "uniprot_id": "TOPRS_MOUSE",
            "id": "Q80Z37-1",
            "name": "E3 ubiquitin-protein ligase Topors",
            "aln": "MGSQPPPPGSPLSREEGEAPPLVPAEEGRRRSRRVRLRGSCRHRPSLLSRRELASNGPAVPATASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFTNPEVRRFRYRTTMTRERSASLYSPSSTVSRRTTTPPDSGVLFEGLGISTRPRDVDIPQFMRQMALRGPTTTDERSLRKIQEQDIINFRRTLYRAGVRVRSIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCP-PSSEEGSRSDSSVITISPDEAETQELDMNASTVRQAPWDDETPGPSYSSSEQVHVGVSSLLNSSDSSDEELVSGGTTSQIQGVQTNDDVNNDSDSSSDNCVIVGFVKPLAERTPELVELSSDSEELGPYEKVETVKTQEQEQSYSSGDSDVSRASSPRSVLGKDEQMSKSHCDSDTRISSKKEEKRSTSLPAPRDS-SSTRGDRVCSPYNHRHRKGGRSRSSDSRSQSRSGHDPRNHRK-HGKKRLRNKRSRSRESSSRPRARKDKKRSRTRDSSWSRRSQTLSLSSGSTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSKYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRIQSFSERTNARKKN-HSERKYYYYERRRSRSVSSNRSRTTSAGPDRVRNEKPGGKRKYKTRHLEGTSEEAQPAREFTSKGKDSHYQK--SKLDGSYKNESDSFSDSRSSDRETKHKRRRRRTRSLSVEIVYEGKATDTSKHHKKKKKKHKKKHKKHHGDNTSRSPVVITIDSDSDGESEVKAGIECSNGSLPQPIQD-------GAFETKDVVTIEDELGVLDKDCDVTALADDLSTS-QTVENCDSPAVPVEQTLDVREESTFASDLESQSSN-VSIQAEPSRPVPSPRTSLSSVSPGRDCDVS",
            "tax_id": 10090,
            "tax_name": "Mouse"
        },
        {
            "uniprot_ac": "A0A8I6ANV8-1",
            "uniprot_id": "A0A8I6ANV8_RAT",
            "id": "A0A8I6ANV8-1",
            "name": "RING-type E3 ubiquitin transferase",
            "aln": "MGSQPPPLGSPLSREEGEAPPLAPAEEGRRRSRRVRLRGSCRHRPSLLGRRELASSGPAVPATASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFTAPEVRRFRYRTTMTRERNASLYSPSSTVSRRTSTPPDSGVLFEGLGISTRPRDVDIPQFMRHMALRGPTATDERSLRKVQEQDIINFRRTLYRAGVRVRSIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCP-PSSEEGSRSDSSVITISPDEAEAQELDVNVSTIRQAPWDDETPGPSYSNSEQVHVGVSSLLNSSDSSDEELVSGGAASQIQGVQANDDVNNDSDSSSDNCVIVGFVKPLAERTPELVELSSDSEELGSYEKMETVKTQEQEQSYSSGDSDASRASSPRSVLGKDEQMGKSHCDSDTRINSKKEEKRSTSLSTPRDS-SSTRGDRACSPYNHRHRKGGRSRSSDSRSQSRSGHDQRNHRKHHGKKRLKNKRSRSRESSSKPRARKDKKRSRTRDSSWSRRSQTLSLSSGSTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSKYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRIQSFSERTNARRKN-HSERKYYYYERHRSRSVSSNRSRTTSAVPDRMRNEKPGGKRKYKTRHLEDTNEEAQPSRAFASRVKESHYQKP-SKLDGGSKDESDSFSDSRPSDRETKHKRRKRRARSLSVEIVYEGKATDTSKHHKKKKKKHKKKHRKHHGDNTSRSPVVITIDSDSDGDAGVKASVECSQSSLPQPGQDEVSTPSSEAFETKDVVTIEDELAVEDKECDVTALTNDLSTS-QAVESSESPPVSVEQTLDVREDSTFASDVESQSSN-ASIPTEPSRPLPSPRTSLSSVSPGRDCDMS",
            "tax_id": 10116,
            "tax_name": "Rat"
        },
        {
            "uniprot_ac": "Q9NS56-1",
            "uniprot_id": "TOPRS_HUMAN",
            "id": "Q9NS56-1",
            "name": "E3 ubiquitin-protein ligase Topors",
            "aln": "MGSQPP-LGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARPAPASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVTPD-RRFRYRTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLGISTRPRDVEIPQFMRQIAVRRPTTADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESS-RPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFGVLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQTEPSRQLPSPRTSLMSVCLGRDCDMS",
            "tax_id": 9606,
            "tax_name": "Human"
        }
    ],
    "algorithm": {
        "name": "clustalw2",
        "url": "http://www.clustal.org/clustal2/",
        "parameter": "Default Clustalw2 parameters"
    },
    "consensus": "******  ************* .**.********************:*. ****:..** **.*************************************************************************************************************. *: ********:****.**:****..*.***:*********************:******::*:* **::*******:****************.***.********************************************************************************************************** ** ****:**************:****:*.:*: **************.****** :*****:*********:**::*******:***:*****.*****************************:**.***:******************.**.***:********:.*.****.***.***********.:**:  **.****. ********* ***************** :**** *****::.********* :**.*:*********************** *********************************:*****************************************:**********:** ***********:****:*******:*: .**:*****************.*.* ***:* *:*: *:*****  *****. *:***:*****.**********:*::****************:**************:******:************** :: ** . **.:..  :* *:        .********** *:.* **:**:::*:::*..: ::*:.  . ...*********:***.**:*.*.** .*: :**** :******* **. *****:*",
    "identical_positions": 864,
    "similar_positions": 130,
    "identity": "82.44%"
}