{
    "cls_id": "homologset.mgi.46359730",
    "date": "2024-05-07 12:12:02 EDT-0400",
    "sequences": [
        {
            "uniprot_ac": "Q9P2D0-1",
            "uniprot_id": "IBTK_HUMAN",
            "id": "Q9P2D0-1",
            "name": "Inhibitor of Bruton tyrosine kinase",
            "aln": "MSSPMPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCYNAATIKDVFGRNALHLVSSCGKKGVLDWLIQKGVDLLVKDKESGWTALHRSIFYGHIDCVWSLLKHGVSLYIQDKEGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGATVCVTTRGDIYLLADYQCKKMASKQLNLKKVLVSGGHMEYKVDPEHLKENGGQKICILAMDGAGRVFCWRSVNSSLKQCRWAYPRQVFISDIALNRNEILFVTQDGEGFRGRWFEEKRKSSEKK-EILSNLHNSSSDVSYVSDINSVYERIRLEKLTFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPAVSSSSFFEEFGKLLREADEMDSIHDVTFQVGNRLFPAHKYILAVHSDFFQKLFLSDGNTSEFTDIYQKDEDSAGCHLFVVEKVHPDMFEYLLQFIYTDTCDFLTHGFKPRIHLNKNPEEYQGTLNSHLNKVNFHEDDNQKSAFEVYKSNQAQTVSERQKSKPKSCKKGKNIREDDPVRMLQTVAKKFDFSNLSSRLDGVRFENEKINVIAKNTGNKLKLSQKKCSFLCDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIHSDILKVILDYLYTDEAVVIKESQNVDFICSVLVVADQLLITRLKEICEVALTEKLTLKNAAMLLEFAAMYSAKQLKLSCLQFIGLNMAALLEARSLDVLSDGVLKDLSEFYRKMIPAMDRRVITPYQDGPDISYLEVEDGDIFLKEEINMEQNHSETMFKKAKTKAKKKPRKRSDSSGGYNLSDIIQSPSSTGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTTGFHSDKIEAKVKPYVNGTSPVYSREDLKPWEKSPILKISAPQPIPSNRIDTTSSASWVAGSFSPVSPPVVDLRTIMEIEESRQKCGATPKSHLGKTVSHGVKLSQKQRKMIALTTKENNSGMNSMETVLFTPSKAPKPVNAWASSLHSVSSKSFRDFLLEEKKSVTSHSSGDHVKKVSFKGIENSQAPKIVRCSTHGTPGPEGNHISDLPLLDSPNPWLSSSVTAPSMVAPVTFASIVEEELQQEAALIRSREKPLALIQIEEHAIQDLLVFYEAFGNPEEFVIVERTPQGPLAVPMWNKHGC",
            "tax_id": 9606,
            "tax_name": "Human"
        },
        {
            "uniprot_ac": "Q6ZPR6-1",
            "uniprot_id": "IBTK_MOUSE",
            "id": "Q6ZPR6-1",
            "name": "Inhibitor of Bruton tyrosine kinase",
            "aln": "MDAATPDCTSKCRSLKHALDVLSVVTKGSESQIKSFLARYCYNAATVKDAFGRNAGHLASSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSVFYGHIDCVWSLLKHGVSLYMQDKEGLSPLDLLMKDRPTHVVFKDTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQLGIIPPPASCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICVLAMDGAGRVFCWRSISSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKNSEKKADILPNLHHSSSDVSCVPDTNSVYERIRLEKLPFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDSFHDVTFQVGNRHFPAHKYILAVRSDFFQKLFLSDGSSLELTDVYQKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDLLTHGFKPRMIVKRKAEDCEGSPDSHLHTVNCHVDDKQKSAFEVYRSNQAHTLSERQKSKPKSSKKGKGVGDDDPVRMLQSVAKKFGLSNLSSRLEGVRLENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFSCHKCVLCARLEYFHSMLSRSWIEASSCAALEMPIQSEILKVILDYLYTDEAVVIKESQNVDFVCSVLVVADQLLITRLKEICEVALTENLTLKNAAMLLEFAALYNAGQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISSMQVEDGEVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYTLSDVIQSPPSAGLLKSAKTNSVESLPELLTSDSEGSYAGVASPRDLQSPDFTAGFHSDKVEGKAKPYVNGIPPPCTREDVKPWEKSPTTKS-APQFIPSNRVDTAASSSWLAGSCSPVSPPVVDLRTIMETEENRQKYGAAPKSNLGKIISHGIKLSQKQRKMIALTTKENNSGTNSMEAILTAPSKSPKPANAWAP-LHSPLSRSFRDFLLEEKKPVPGYGSGDHVKKVCFKGTENSPALNVARCSTHGTPGLESNHVSDFPLLDSPNPWQSSSLAASPAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPEEFVVVERAPQGPLAVPMWNKHGC",
            "tax_id": 10090,
            "tax_name": "Mouse"
        }
    ],
    "algorithm": {
        "name": "clustalw2",
        "url": "http://www.clustal.org/clustal2/",
        "parameter": "Default Clustalw2 parameters"
    },
    "consensus": "*.:. *************************.***:**: :******:**.***** **.*************:********************:*******************:*******.***:***********:****:*************************:*******:*:************************* *********************.******************:**********:**********:**************************************:******** ***********:*************:*******************************:************* **********.********:**************:.************** *********************:*:***:***.**** :**.***:****** *.* ************.********************************.****************:*****:********** **********:************.: *:**:******:**************:*******:******:********: ::::.*: :*: :***:.** * **:********:****:*:**********.****.: :********:*****.:*******:***:**********:*************** ************.****************** ***************:*:*************************:*************************:**************:*.* ***************************:.****** *********:************** ::****::*:******* *:**********:***************.***:****.*:*****.***********************.***********:******:*.*.****** .*  :***:*******  *  *** *****:**::*:**:*** *************** **.*** **:***:*** :***:******************** ****::* :***:***.****. ***  *:***********.*..:.********.*** *** * ::.********* *.**:**:********* ***::*.. ************* ******************:**********************:***:***************",
    "identical_positions": 1161,
    "similar_positions": 145,
    "identity": "85.75%"
}