{
    "cls_id": "homologset.mgi.46359068",
    "date": "2024-05-07 12:12:02 EDT-0400",
    "sequences": [
        {
            "uniprot_ac": "Q6PR54-1",
            "uniprot_id": "RIF1_MOUSE",
            "id": "Q6PR54-1",
            "name": "Telomere-associated protein RIF1",
            "aln": "MTAPGRSPLEPLLETWEDPSVPPGEQTDAYLTLTSRMTGEEGKEVIAEIEKNLSRLYTVLKAHISSQNSELSSAALQALGFCLYNPRITSGLSEANIQELLLTLNGIIKSSDKNVCTRALWVISKQTFPAELVSKMVSSIIDSLEVILSKGEIHSAVVDFEALNVIIRLIEQAPVQMGEESVRWAKLVIPLVVHSAQKVHLRGATALEMGMPLLLQKQQEIALITEHLMTTKLISELQKLFKNKNETYVLKLWPLFVKLLGKTLHRSGSFINSLLQLEELGFRSGTPMIKKIAFIAWKSLIDNFALNPDILCSAKRLKLLMQPLSSIHVRTETLALTKLEVWWYLLMRLGPQLPANFEQVCVPLIQSTISVDSIPSPQGNSSRGSASPGLSPLTPGHKGAS-PYGSP---RGNLSSNTGGMAAIPSIQLLGLEMMLHFLLGPEVLSFAKQHKIVLSLEPLEHPLISSPSFFSKYAHTLITAVHDSFVSVGKDASDAVVSAIWKELISLVKSVTEAGNRKEKSGSEVLTLLLKSLENIVKSEVFPVSKTLVLMEITVKGLPPKVLGSPAYQVANMDILNGTPALFLIQLIFNNNLLECGVEDEKFFLNLETLVGCVLSGPTSPLAFSDSVLTVINQNAKQLVNKEHLWRMWSMIVSPLTDVIHQTNEVNQGDALEHNFSAIYGALTLPINHIFSAQTFPTGTMKALLKTWSELYRAFTRCASLVATAEENLCCEELSSKIMCSLEDEVLSDLLFLDRISHIIIVMVDCIDFSPYNKKYQPKIKSPQRSSDWSRKKKEPLGKLASLFKLIVKVIDTFHTLSLKETFSDTLLAIGNSIISMLSNVFGHISLPSMIREIFATFTRPLALLYENSKLDEAPKVYTSLNNKLEKLLGEIVACLQFSYLGAYDSELLEHLSPLLCVIFLHKNKQIRKQSALLWNATFAKATALVYPEELKPILRQAKQKILLLLPGLENVEMMDESSEPYSESTENSQLNVKISGMERKSSGKRDSILAHTKDKKKKVKLSAKLKLESSSPKIKSGKLLEEEKSTDFVFIPPEGKETKARVLTEHQKEVLKTKRCDIPALYNNLDASQDTLFSAQFSQEESMESLTLTEKPKEDAKIIK-EEQMESTIFIHQDAPENCGIDEHSENASLPN--CGGSVAETNPETLITGFDARKEVLISSKILSAESSSSTETS-VVSSSSVSNATFSGTPPQPTSRRQTFITLEKFDGSETRPFSPSPLNNISSTVTVRNNQDNTTNTDMPPKARKREVTNSKSDSENLANAGKKSSRRWSKAEQSVTKKSKPSLTSEQEEHSSE---------NNSPDLLSPTEHVSENDDHPSEATLEHKDGDPKPAVEN--ASLEDLTTEEKNVGINMESKESTASVVARTEQIVNEDSQAAALAPNPKTLRRSSRRRSEAVDSCSDSQERESGQQKKERRKEEEKIISKSPLRIKDDKLPTQKLTDESPIQENLTEKGNTLPERTSGEPSVNAEIDQNRRKPDLENVSSEGGGGTLDNLDKSSEKPLRGRTRYQTRRASQGLISAVENSESDSSEAKEEVSRKKRSGKWKNRSSDSVDIEEQEEKKAEEEVMKTANQTLDGQAVPDVDVNAAAQVCEKSTNNNRVILQDSAGPADSLQAPPKG----EEKSKINKCVDSSFVSLPVPESNLRTRNASKRLLYKQDND-------SNVRVSD-SSLSPEKFTQVECQHKRSRRVRRSKSCDCCGEKSQSQEKSFIGLKNTESYAIKSVEKKKTDLQVPETAPETREARDHAETKLAGEEPLVNFHVGLKEENCTTGDS-----VKSEAELQEASLPPEIVTVKEKTYDTDASEAVSEIQGPCSENHSPAEDPGLSECKDISQKQLSENGE------------LDISDVGKACKVIAGSSPEGVETMELNVRNDAFVAADSEKSTQMDVSVDVATEEDNKKDECEAVTTEVNVEGVATEDFNSGMDLSDTPIPVSKDVETEH---AASGEIEGESNESDSGSCEEMNKEMGSHKAQMSTEIDSAR-----VKETDILASASKSEEALIGRLDVNTQSFVSD-IEMSSGERTVNC-KTETSIELNKLDEAKLSGNEATVGNDTLQEVCFTSEKVEKLPQCLLVQVAS-ELGAESNTTSPEKL-ELD-SFGSVNESPSGMQQARCVWSPLASPSTSILKRGLKRSQEDEIS-PVNKIRRVSFADPIYQAGLADDIDRRCSVVRSHSSNSSPIIKSVKTSPTSHSKHNTTSAKGFLSPGSQSSKFKSPKKCLITEMAQESMLSPTESVYPALVNCAASVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVFNVKKALRVYHEQQMKSRGLEEIPIFDISEKAVNGVESRTVSTDEERFASDLIEPVTLDTPLSKNLVAQISALALQLDSEDLYSYTGSQLFEMHEKLGTMANSIIRNLQSRWRSPAHENS-",
            "tax_id": 10090,
            "tax_name": "Mouse"
        },
        {
            "uniprot_ac": "Q5UIP0-1",
            "uniprot_id": "RIF1_HUMAN",
            "id": "Q5UIP0-1",
            "name": "Telomere-associated protein RIF1",
            "aln": "MTARGQSPLAPLLETLEDPSASHGGQTDAYLTLTSRMTGEEGKEVITEIEKKLPRLYKVLKTHISSQNSELSSAALQALGFCLYNPKITSELSEANALELLSKLNDTIKNSDKNVRTRALWVISKQTFPSEVVGKMVSSIIDSLEILFNKGETHSAVVDFEALNVIVRLIEQAPIQMGEEAVRWAKLVIPLVVHSAQKVHLRGATALEMGMPLLLQKQQEIASITEQLMTTKLISELQKLFMSKNETYVLKLWPLFVKLLGRTLHRSGSFINSLLQLEELGFRSGAPMIKKIAFIAWKSLIDNFALNPDILCSAKRLKLLMQPLSSIHVRTETLALTKLEVWWYLLMRLGPHLPANFEQVCVPLIQSTISIDSNASPQGNSCHVATSPGLNPMTPVHKGASSPYGAPGTPRMNLSSNLGGMATIPSIQLLGLEMLLHFLLGPEALSFAKQNKLVLSLEPLEHPLISSPSFFSKHANTLITAVHDSFVAVGKDAPDVVVSAIWKELISLVKSVTESGNKKEKPGSEVLTLLLKSLESIVKSEVFPVSKTLVLMEITIKGLPQKVLGSPAYQVANMDILNGTPALFLIQLIFNN-FLECGVSDERFFLSLESLVGCVLSGPTSPLAFSDSVLNVINQNAKQLENKEHLWKMWSVIVTPLTELINQTNEVNQGDALEHNFSAIYGALTLPVNHIFSEQRFPVATMKTLLRTWSELYRAFARCAALVATAEENLCCEELSSKIMSSLEDEGFSNLLFVDRIIYIITVMVDCIDFSPYNIKYQPKVKSPQRPSDWSKKKNEPLGKLTSLFKLIVKVIYSFHTLSFKEAHSDTLFTIGNSITGIISSVLGHISLPSMIRKIFATLTRPLALFYENSKLDEVPKVYSCLNNKLEKLLGEIIACLQFSYTGTYDSELLEQLSPLLCIIFLHKNKQIRKQSAQFWNATFAKVMMLVYPEELKPVLTQAKQKFLLLLPGLETVEMMEESSGPYSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKENMKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEVLKTKRCDIPAMYNNLDVSQDTLFT-QYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECG-SLDKTSPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFDGSENRPFSPSPLNNISSTVTVKNNQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDNQVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQ-VQITPNQKTLRRSSRRRSEVVESTTESQDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDG-TQDIVDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKRLHKRDSFDNCSLGESSKIGISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQFLDEHHSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQESLETKEEKPEETPKMELSLENVTVEGNACKVTESN-LEKAKTMELNVGNEASFHG--QERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNSDISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTAEMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEE-KLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLRELDPSLVSANDSPSGMQT-RCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVKTSPTTQSKHNTTSAKGFLSPGSRSPKFKSSKKCLISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVSNVKKALRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSPDEERLVSDIIDPVALEIPLSKNLLAQISALALQLDSEDLHNYSGSQLFEMHEKLSCMANSVIKNLQSRWRSPSHENSI",
            "tax_id": 9606,
            "tax_name": "Human"
        }
    ],
    "algorithm": {
        "name": "clustalw2",
        "url": "http://www.clustal.org/clustal2/",
        "parameter": "Default Clustalw2 parameters"
    },
    "consensus": "*** *:*** ***** ****.. * *********************:****:*.***.***:************************:*** *****  *** .**. **.***** *************:*:*.***********:::.*** *************:*******:*****:***************************************** ***:************** .******************:***********************:*****************************************************************:******************:** .******.: ::****.*:** ***** ***:*   * ***** ****:***********:********.******:*:********************:*:***********:*****.*.******************:**:***.*************.*******************:**** ******************************* :*****.**:***.**:********************.********* ******:***:**:***::*:*************************:***** * **..***:**:*********:***:*******************.***** :*:***:*** :** ************ *****:*****.****:**:******:********** :*****:**:.****::***** .::*.*:**********:****:******:********.****:.************:******* *:*******:******:************** :*******.  *********:* *****:********.****:*** ***:.*****************.*****:**:**:**:::* :********* *:*.  ******************::* *:**:***************:*****.******: *:****.**  ***.*****:*::  ****:* *.* **..*:**: ** *::**.*  ** *: :*.**   :. * **:.****:  *:*.:****.* *********:*.:**** ******************.*****************:***:.  :**: ***::** * ******::.*. *:**** .****: .*:*** : ** *:::.*         **.*.**. ** **:*: * **:*:**.: . *.*. :  . **  *.***** **:****.*..**  ::*:****** . ::** ************.*:* ::**::*..:*********** :.****:**** **.***  *..:**** ***..* *:* **.*.*** :**::*.* **:.***.* * * :****** :***************:*::************* ***********:*.:****::**** .::* :*: **: * :*..: **.  : :***. :.* ** ***: .:* **.* .     ***.: .* .: **.************** ***  ::. *       *:: :** **** :.*  :**************.*********.****:*******.  ::  *.**:*:*.* :..** :*. ::* :: .*.  ****:****:* * .**     .**: :  : ***. **..:*:  * *:***:*  .  ..:::  : .* *.:.*::**:.*. : *             :::  *:****  ..  * .:****** *:* . .  :: *: .:* :.* **::::*:.** *:::*.: ****:***.:.***.. **. :.:**    :*:**::* .: **  *.** *.:* .::  *  *  :       .:: .* :.:**.:**  . * .: :.**.* :***: *  ::. ****. * .* :* **..*: .: .* ***  .**:***: .***   .*  **  *.*.:**:** *** *: *.*:******  **************************** ****:***********************:*********** ********::****************:*.****.*****:***:**: .*******.****.*.************************************************** *******:*****:*:*******:******:***:*.:::*.****:.**:*:**:*: ******:***************:.*:***********. ****:*:*********:**** ",
    "identical_positions": 1729,
    "similar_positions": 461,
    "identity": "69.66%"
}