{
    "uniprot_canonical_ac": "P0DTA3-1",
    "uniprot_ac": "P0DTA3",
    "uniprot_id": "SPD11_HUMAN",
    "mass": {
        "chemical_mass": 31441.0,
        "monoisotopic_mass": 31441.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "SPDYE11",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P0DTA3",
            "id": "P0DTA3"
        }
    ],
    "protein_names": [
        {
            "name": "Putative speedy protein E11",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P0DTA3"
        }
    ],
    "function": [
        {
            "annotation": "Acts as a modulator of the nicotinic acetylcholine receptor alpha-7 (CHRNA7) activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0DTA3",
                    "url": "https://www.uniprot.org/uniprot/P0DTA3#function"
                },
                {
                    "database": "PubMed",
                    "id": "27789755",
                    "url": "https://glygen.org/publication/PubMed/27789755"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0DTA3",
                    "url": "https://www.uniprot.org/uniprot/P0DTA3"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "SPDYE11",
            "url": "https://www.uniprot.org/uniprot/P0DTA3",
            "locus": {
                "chromosome": "7",
                "start_pos": 73047862,
                "end_pos": 73057911,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000275976",
                        "url": "https://www.ensembl.org/id/ENSG00000275976"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000286228",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000286228",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "SPDYE11",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=SPDYE11",
            "database": "GeneCards",
            "categories": [
                "Gene Annotation",
                "Organism-specific"
            ]
        },
        {
            "id": "51507",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=51507",
            "database": "HGNC",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "IPR020984",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020984",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NX_P0DTA3",
            "url": "https://www.nextprot.org/entry/NX_P0DTA3",
            "database": "neXtProt",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "KXYLAND",
            "url": "https://omabrowser.org/oma/group/KXYLAND/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4655013at2759",
            "url": "http://www.orthodb.org/?query=4655013at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR31156",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31156",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR31156:SF15",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31156:SF15",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF11357",
            "url": "http://pfam.xfam.org/family/PF11357",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_016885939",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016885939",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P0DTA3",
            "url": "https://www.uniprot.org/uniprot/P0DTA3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P0DTA3-1",
            "url": "https://www.uniprot.org/uniprot/P0DTA3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS",
        "length": 265,
        "header": "sp|P0DTA3-1|SPD11_HUMAN Isoform 1 of Putative speedy protein E11  OS=Homo sapiens OX=9606 GN=SPDYE11 PE=5 SV=1 CANONICAL=P0DTA3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P0DTA3-1",
            "url": "",
            "sequence": {
                "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS",
                "length": 265,
                "header": "sp|P0DTA3-1|SPD11_HUMAN Isoform 1 of Putative speedy protein E11  OS=Homo sapiens OX=9606 GN=SPDYE11 PE=5 SV=1 CANONICAL=P0DTA3-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 73056111,
                "end_pos": 73050245,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000340073.9",
                        "url": "https://www.ensembl.org/id/ENST00000340073.9"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000498510.1",
                        "url": "https://www.ensembl.org/id/ENSP00000498510.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "A Genome-Wide Arrayed cDNA Screen to Identify Functional Modulators of \u03b17 Nicotinic Acetylcholine Receptors.",
            "journal": "SLAS discovery : advancing life sciences R & D",
            "date": "2017-02",
            "authors": "Rex Elizabeth B, Shukla Nikhil, Gu Shenyan, Bredt David, DiSepio Daniel",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0DTA3",
                    "url": "https://www.uniprot.org/uniprot/P0DTA3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27789755",
                    "url": "https://glygen.org/publication/PubMed/27789755"
                }
            ]
        }
    ],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "acetylcholine receptor regulator activity",
                        "id": "GO:0030548",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030548",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DTA3",
                                "url": "https://www.uniprot.org/uniprot/P0DTA3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein kinase binding",
                        "id": "GO:0019901",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DTA3",
                                "url": "https://www.uniprot.org/uniprot/P0DTA3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 215,
            "end_pos": 217,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 215,
                "end_pos": 217
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}
