{ "uniprot_canonical_ac": "P0DPA0-1", "uniprot_ac": "P0DPA0", "uniprot_id": "PAHX_DICDI", "mass": { "chemical_mass": 40645.0, "monoisotopic_mass": 40645.0 }, "refseq": {}, "gene_names": [ { "name": "DDB_G0349042", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/P0DPA0", "id": "P0DPA0" } ], "protein_names": [ { "name": "Putative phytanoyl-CoA dioxygenase", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P0DPA0" }, { "name": "1.14.11.18", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0DPA0" }, { "name": "PhyH", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0DPA0" }, { "name": "Phytanic acid oxidase", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0DPA0" }, { "name": "Phytanoyl-CoA alpha-hydroxylase", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P0DPA0" } ], "function": [ { "annotation": "Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.", "evidence": [ { "database": "UniProtKB", "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0#function" }, { "database": "UniProtKB", "id": "O14832", "url": "https://www.uniprot.org/uniprot/O14832#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ], "common_name": "Cellular slime molds" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprot/P0DPA0", "locus": {} } ], "crossref": [ { "id": "DDB_G0349042", "url": "http://dictybase.org/gene/DDB_G0349042", "database": "dictyBase", "categories": [ "Organism-specific" ] }, { "id": "IPR008775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31630:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31630:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05721", "url": "http://pfam.xfam.org/family/PF05721", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P0DPA0", "url": "http://purl.obolibrary.org/obo/PR_P0DPA0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "16065", "url": "https://www.rhea-db.org/rhea/16065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0DPA0-1", "url": "https://www.uniprot.org/uniprot/P0DPA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEILKSFKISIDNEGYSKSFSLEDLDNFNNNNNNNNNNNNNEENNPYEFFERYGFLVIRNVISEEDCNKTVGEIFDIIESKVKTFDRNDQSTWDQTFSEDGSSIPQYGSPSKPPIFKKQFLMNRTNPNVYKVFSKLLKNQDLMVNHDRACFFRPTLVNPKWKTNDNVHLDMNPYNWMGNGDICREELSKLTYARLGEFIVENNQPTQNDGLQLQGVINLLDNQELDGGYCVTPGFHTIFNEYFTSKKPQYTSPSWNFDKKDIAFKYAKRISMRKGSIVVWNQQMPHGSMSNKSFNPRMAQFIKIFPTSTVNSVRYQHRKNQIKSIIENSDELKDFPLNQISSQLLGLN", "length": 349, "header": "sp|P0DPA0-1|PAHX_DICDI Isoform 1 of Putative phytanoyl-CoA dioxygenase OS=Dictyostelium discoideum OX=44689 GN= PE=3 SV=1 CANONICAL=P0DPA0-1" }, "isoforms": [ { "isoform_ac": "P0DPA0-1", "url": "", "sequence": { "sequence": "MEEILKSFKISIDNEGYSKSFSLEDLDNFNNNNNNNNNNNNNEENNPYEFFERYGFLVIRNVISEEDCNKTVGEIFDIIESKVKTFDRNDQSTWDQTFSEDGSSIPQYGSPSKPPIFKKQFLMNRTNPNVYKVFSKLLKNQDLMVNHDRACFFRPTLVNPKWKTNDNVHLDMNPYNWMGNGDICREELSKLTYARLGEFIVENNQPTQNDGLQLQGVINLLDNQELDGGYCVTPGFHTIFNEYFTSKKPQYTSPSWNFDKKDIAFKYAKRISMRKGSIVVWNQQMPHGSMSNKSFNPRMAQFIKIFPTSTVNSVRYQHRKNQIKSIIENSDELKDFPLNQISSQLLGLN", "length": 349, "header": "sp|P0DPA0-1|PAHX_DICDI Isoform 1 of Putative phytanoyl-CoA dioxygenase OS=Dictyostelium discoideum OX=44689 GN= PE=3 SV=1 CANONICAL=P0DPA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome of the social amoeba Dictyostelium discoideum.", "journal": "Nature", "date": "2005", "authors": "Eichinger L, Pachebat J A, Gl\u00f6ckner G, Rajandream M-A, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov B A, Rivero F, Bankier A T, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail M A, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox E C, Chisholm R L, Gibbs R, Loomis W F, Platzer M, Kay R R, Williams J, Dear P H, Noegel A A, Barrell B, Kuspa A", "evidence": [ { "database": "UniProtKB", "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ], "reference": [ { "type": "PubMed", "id": "15875012", "url": "https://glygen.org/publication/PubMed/15875012" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ], "pmid": "" }, { "name": "phytanoyl-CoA dioxygenase activity", "id": "GO:0048244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048244", "evidence": [ { "database": "UniProtKB", "id": "P0DPA0", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16065", "name": "", "equation": "2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P57093-1", "O14832-1", "O35386-1", "P0DPA0-1" ], "evidence": [ { "id": "16065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "O14832", "gene_name": "PHYH", "activity": [ { "ec_number": "1.14.11.18", "activity": "2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.", "evidence": [ { "id": "O14832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14832" } ] }, { "ec_number": "1.14.11.18", "activity": "", "evidence": [ { "id": "O14832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14832" } ] } ] }, { "uniprot_ac": "O35386", "gene_name": "Phyh", "activity": [ { "ec_number": "1.14.11.18", "activity": "2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.", "evidence": [ { "id": "O35386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35386" } ] }, { "ec_number": "1.14.11.18", "activity": "", "evidence": [ { "id": "O35386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35386" } ] } ] }, { "uniprot_ac": "P0DPA0", "gene_name": "", "activity": [ { "ec_number": "1.14.11.18", "activity": "2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.", "evidence": [ { "id": "P0DPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ] }, { "ec_number": "1.14.11.18", "activity": "", "evidence": [ { "id": "P0DPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DPA0" } ] } ] }, { "uniprot_ac": "P57093", "gene_name": "Phyh", "activity": [ { "ec_number": "1.14.11.18", "activity": "2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.", "evidence": [ { "id": "P57093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57093" } ] }, { "ec_number": "1.14.11.18", "activity": "", "evidence": [ { "id": "P57093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P57093" } ] } ] } ], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 69, "end_pos": 71 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }