{
    "uniprot_canonical_ac": "A6NE82-1",
    "uniprot_ac": "A6NE82",
    "uniprot_id": "MB3L3_HUMAN",
    "mass": {
        "chemical_mass": 23095.0,
        "monoisotopic_mass": 23095.0
    },
    "refseq": {
        "ac": "NP_001157897",
        "name": "putative methyl-CpG-binding domain protein 3-like 3",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157897"
    },
    "gene_names": [
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            "name": "MBD3L3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A6NE82",
            "id": "A6NE82"
        },
        {
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            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157897",
            "id": "NP_001157897"
        }
    ],
    "protein_names": [
        {
            "name": "Putative methyl-CpG-binding domain protein 3-like 3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A6NE82"
        },
        {
            "name": "MBD3-like 3; MBD3-like protein 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157897",
            "id": "NP_001157897"
        },
        {
            "name": "MBD3-like protein 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A6NE82"
        },
        {
            "name": "putative methyl-CpG-binding domain protein 3-like 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157897",
            "id": "NP_001157897"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [
        {
            "tissue": {
                "name": "Adult mammalian kidney",
                "namespace": "UBERON",
                "id": "0000082",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000082"
            },
            "score": "18.51",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000182315",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
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            ]
        },
        {
            "tissue": {
                "name": "Stomach",
                "namespace": "UBERON",
                "id": "0000945",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000945"
            },
            "score": "16.41",
            "present": "ABSENT",
            "evidence": [
                {
                    "database": "Bgee",
                    "id": "ENSG00000182315",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
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            ]
        },
        {
            "tissue": {
                "name": "Esophagus",
                "namespace": "UBERON",
                "id": "0001043",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043"
            },
            "score": "17.43",
            "present": "LOW",
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                {
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                    "id": "ENSG00000182315",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
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            ]
        },
        {
            "tissue": {
                "name": "Rectum",
                "namespace": "UBERON",
                "id": "0001052",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001052"
            },
            "score": "23.34",
            "present": "ABSENT",
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                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
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            ]
        },
        {
            "tissue": {
                "name": "Urinary bladder",
                "namespace": "UBERON",
                "id": "0001255",
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255"
            },
            "score": "16.34",
            "present": "ABSENT",
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                {
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                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
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            ]
        },
        {
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                "name": "Thyroid gland",
                "namespace": "UBERON",
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            },
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                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
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            ]
        },
        {
            "tissue": {
                "name": "Liver",
                "namespace": "UBERON",
                "id": "0002107",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107"
            },
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            "present": "ABSENT",
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                {
                    "database": "Bgee",
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                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
                }
            ]
        },
        {
            "tissue": {
                "name": "Prostate gland",
                "namespace": "UBERON",
                "id": "0002367",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367"
            },
            "score": "14.41",
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                {
                    "database": "Bgee",
                    "id": "ENSG00000182315",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
                }
            ]
        },
        {
            "tissue": {
                "name": "Thoracic mammary gland",
                "namespace": "UBERON",
                "id": "0005200",
                "url": "http://purl.obolibrary.org/obo/UBERON_0005200"
            },
            "score": "17.17",
            "present": "ABSENT",
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                {
                    "database": "Bgee",
                    "id": "ENSG00000182315",
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315"
                }
            ]
        }
    ],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A6NE82",
                    "url": "https://www.uniprot.org/uniprot/A6NE82"
                }
            ],
            "common_name": "Human"
        }
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            "name": "MBD3L3",
            "url": "https://www.uniprot.org/uniprot/A6NE82",
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                "evidence": [
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                        "database": "Ensembl Gene",
                        "id": "ENSG00000182315",
                        "url": "https://www.ensembl.org/id/ENSG00000182315"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000182315",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182315",
            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "MBD3L3",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=MBD3L3",
            "database": "GeneCards",
            "categories": [
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                "Organism-specific"
            ]
        },
        {
            "id": "653657",
            "url": "https://www.ncbi.nlm.nih.gov/gene/653657",
            "database": "GeneID",
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            ]
        },
        {
            "id": "37205",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=37205",
            "database": "HGNC",
            "categories": [
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            ]
        },
        {
            "id": "A6NE82",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A6NE82*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR025884",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR025884",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032343",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032343",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "hsa:653657",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:653657",
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            "categories": [
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            ]
        },
        {
            "id": "NX_A6NE82",
            "url": "https://www.nextprot.org/entry/NX_A6NE82",
            "database": "neXtProt",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "EVRYNQW",
            "url": "https://omabrowser.org/oma/group/EVRYNQW/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4849303at2759",
            "url": "http://www.orthodb.org/?query=4849303at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14048",
            "url": "http://pfam.xfam.org/family/PF14048",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF16564",
            "url": "http://pfam.xfam.org/family/PF16564",
            "database": "Pfam",
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                "Protein Classification"
            ]
        },
        {
            "id": "A6NE82",
            "url": "https://pharos.nih.gov/targets/A6NE82",
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            ]
        },
        {
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            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157897",
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            ]
        },
        {
            "id": "A6NE82",
            "url": "https://www.uniprot.org/uniprot/A6NE82",
            "database": "UniProtKB",
            "categories": [
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            ]
        },
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            "id": "A6NE82-1",
            "url": "https://www.uniprot.org/uniprot/A6NE82-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MGEPAFTSFPSPPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARQAEMLTCR",
        "length": 208,
        "header": "sp|A6NE82-1|MB3L3_HUMAN Isoform 1 of Putative methyl-CpG-binding domain protein 3-like 3  OS=Homo sapiens OX=9606 GN=MBD3L3 PE=5 SV=1 CANONICAL=A6NE82-1"
    },
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        {
            "isoform_ac": "A6NE82-1",
            "url": "",
            "sequence": {
                "sequence": "MGEPAFTSFPSPPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARQAEMLTCR",
                "length": 208,
                "header": "sp|A6NE82-1|MB3L3_HUMAN Isoform 1 of Putative methyl-CpG-binding domain protein 3-like 3  OS=Homo sapiens OX=9606 GN=MBD3L3 PE=5 SV=1 CANONICAL=A6NE82-1"
            },
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                "start_pos": 7058605,
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                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000333843.9",
                        "url": "https://www.ensembl.org/id/ENST00000333843.9"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000333183.4",
                        "url": "https://www.ensembl.org/id/ENSP00000333183.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "hsa:653657",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:653657",
            "resource": "KEGG Pathway"
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            "uniprot_canonical_ac": "A6NDZ8-1",
            "protein_name": "Putative methyl-CpG-binding domain protein 3-like 4",
            "gene_name": "MBD3L4",
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                "sequence": "MGEPAFTSFPSPPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRIPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARQAEMLTCR",
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            },
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                {
                    "id": "45934557",
                    "url": "http://www.informatics.jax.org/homology/45934557",
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                }
            ],
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        },
        {
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            "protein_name": "Putative methyl-CpG-binding domain protein 3-like 5",
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            "organism": "Homo sapiens",
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                "sequence": "MGEPAFTSFPSPPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRIPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARQAEMLTGG",
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            },
            "evidence": [
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                    "id": "45934557",
                    "url": "http://www.informatics.jax.org/homology/45934557",
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                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q3UXB0-1",
            "protein_name": "Methyl-CpG binding domain protein 3-like 2",
            "gene_name": "Mbd3l2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MEETSRNSVSSQPLIGSLTRSMILNKLQKRRETQIVPKKIKAKHRTGVTSKDSMRMTSCIFAKPVTTITSYPENETRYRREEDKLTKPKQLCALKRLKKHQVGENKQDLSCQLKLTNPVERIALGMRDETNDQSGVKGQLTPGEVTSVQTPCLEKNEQMAFQLSPFFSSPGVTMPVRLHLSPSYFIQEVTIADILSQIWKVKKARKRLEVALEADSLARQAENMGEQR",
                "length": 228
            },
            "evidence": [
                {
                    "id": "45934557",
                    "url": "http://www.informatics.jax.org/homology/45934557",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8NHZ7-1",
            "protein_name": "Methyl-CpG-binding domain protein 3-like 2",
            "gene_name": "MBD3L2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGEPAFTSFPSLPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARRAEMLTGG",
                "length": 208
            },
            "evidence": [
                {
                    "id": "45934557",
                    "url": "http://www.informatics.jax.org/homology/45934557",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "negative regulation of transcription by RNA polymerase II",
                        "id": "GO:0000122",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122",
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                                "database": "UniProtKB",
                                "id": "A6NE82",
                                "url": "https://www.uniprot.org/uniprot/A6NE82"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "DNA methylation-dependent heterochromatin formation",
                        "id": "GO:0006346",
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                            {
                                "database": "UniProtKB",
                                "id": "A6NE82",
                                "url": "https://www.uniprot.org/uniprot/A6NE82"
                            }
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                        "pmid": ""
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                ]
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            {
                "name": "Cellular Component",
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                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
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                                "id": "A6NE82",
                                "url": "https://www.uniprot.org/uniprot/A6NE82"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "methyl-CpG binding",
                        "id": "GO:0008327",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327",
                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "A6NE82",
                                "url": "https://www.uniprot.org/uniprot/A6NE82"
                            }
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                        "pmid": ""
                    }
                ]
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        ]
    },
    "pro_annotation": [],
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": []
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        {
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        {
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