{ "uniprot_canonical_ac": "A0A286ZZP4-1", "uniprot_ac": "A0A286ZZP4", "uniprot_id": "A0A286ZZP4_PIG", "mass": { "chemical_mass": 68807.0, "monoisotopic_mass": 68807.0 }, "refseq": {}, "gene_names": [ { "name": "GCKR", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4", "id": "A0A286ZZP4" } ], "protein_names": [ { "name": "Glucokinase regulator", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A286ZZP4" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "common_name": "Pig" } ], "gene": [ { "name": "GCKR", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4", "locus": { "chromosome": "KQ004350.1", "start_pos": 504443, "end_pos": 477123, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00005044101", "url": "https://www.ensembl.org/id/ENSSSCG00005044101" } ] } } ], "crossref": [ { "id": "ENSSSCG00000028672", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000028672", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "7403at2759", "url": "http://www.orthodb.org/?query=7403at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10088:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10088:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20741", "url": "http://pfam.xfam.org/family/PF20741", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZZP4-1", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L883", "url": "https://www.uniprot.org/uniprot/I3L883", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3L883-1", "url": "https://www.uniprot.org/uniprot/I3L883-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGTKRFQHVIETPEPGKWELSGYEAALPITEKSNPLTQDLDKADAKEIVRLLGQCDAEIFQEEGQVMPTYQRLYSESTLTTMVQVAGKVQEVLKEPEGGLVVLSGGGTSGRMAFLMSVSFNQLMRGLGQKPLYTYLIAGGDRNLHLNKHGGGDSDAHGPQAGLEYPPTPAPSPSSCPPLSSCHQAPFVAGQMDYCMDNPAVFLPVLVGFNPVSMARNDPIEDWSSTFRQIAERMQKLQEKQEAFVLNPAIGPEGLSGCSRLKGGSATKVLLETLLLAAHKTVDRGIEASPRCLLEILRTFERAHQVTYSQSAKIAALMKQASTSLEKKGRVHLVGWQTLGIIAIMDGVECIHSFGADFRDIRGFLIGDHSDMFNQKAELINQGSHFTFSQEDFLTSILPALTEVDTVVFIFTLDDNLAEVQTLVEQVKEKTSNIQALAHGTVGQSLPTPLKKLFPSIISITWPLLFFEYEGNFIQKFQHELSTKWVLNTVSTGAHVLLGKILQNHTLDLRIRNSKLFWRALSMLQRFSGQPKARCIESLLQAIHFPQPLSDDVRAAPISFHVQAADKKEQVIPIALLSLLFRCSIPEAQAHLAGAPSVCEAIRSALTGPGRKRNADALETLEPALP", "length": 627, "header": "tr|A0A286ZZP4-1|A0A286ZZP4_PIG Isoform 1 of Glucokinase regulator OS=Sus scrofa OX=9823 GN=GCKR PE=1 SV=2 CANONICAL=A0A286ZZP4-1" }, "isoforms": [ { "isoform_ac": "A0A286ZZP4-1", "url": "", "sequence": { "sequence": "MPGTKRFQHVIETPEPGKWELSGYEAALPITEKSNPLTQDLDKADAKEIVRLLGQCDAEIFQEEGQVMPTYQRLYSESTLTTMVQVAGKVQEVLKEPEGGLVVLSGGGTSGRMAFLMSVSFNQLMRGLGQKPLYTYLIAGGDRNLHLNKHGGGDSDAHGPQAGLEYPPTPAPSPSSCPPLSSCHQAPFVAGQMDYCMDNPAVFLPVLVGFNPVSMARNDPIEDWSSTFRQIAERMQKLQEKQEAFVLNPAIGPEGLSGCSRLKGGSATKVLLETLLLAAHKTVDRGIEASPRCLLEILRTFERAHQVTYSQSAKIAALMKQASTSLEKKGRVHLVGWQTLGIIAIMDGVECIHSFGADFRDIRGFLIGDHSDMFNQKAELINQGSHFTFSQEDFLTSILPALTEVDTVVFIFTLDDNLAEVQTLVEQVKEKTSNIQALAHGTVGQSLPTPLKKLFPSIISITWPLLFFEYEGNFIQKFQHELSTKWVLNTVSTGAHVLLGKILQNHTLDLRIRNSKLFWRALSMLQRFSGQPKARCIESLLQAIHFPQPLSDDVRAAPISFHVQAADKKEQVIPIALLSLLFRCSIPEAQAHLAGAPSVCEAIRSALTGPGRKRNADALETLEPALP", "length": 627, "header": "tr|A0A286ZZP4-1|A0A286ZZP4_PIG Isoform 1 of Glucokinase regulator OS=Sus scrofa OX=9823 GN=GCKR PE=1 SV=2 CANONICAL=A0A286ZZP4-1" }, "locus": { "chromosome": "3", "start_pos": 111676701, "end_pos": 111649801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000056390.3", "url": "https://www.ensembl.org/id/ENSSSCT00000056390.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000037171.2", "url": "https://www.ensembl.org/id/ENSSSCP00000037171.2" } ] } }, { "isoform_ac": "I3L883-1", "url": "", "sequence": { "sequence": "MPGTKRFQHVIETPEPGKWELSGYEAALPITEKSNPLTQDLDKADAKEIVRLLGQCDAEIFQEEGQVMPTYQRLYSESTLTTMVQVAGKVQEVLKEPEGGLVVLSGGGTSGRMAFLMSVSFNQLMRGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDYCMDNPAVFLPVLVGFNPVSMARNDPIEDWSSTFRQIAERMQKLQEKQEAFVLNPAIGDSPSSPNLPLGVIAPQPEGLSGCSRLKGGSATKVLLETLLLAAHKTVDRGIEASPRCLLEILRTFERAHQVTYSQSAKIAALMKQASTSLEKKGRVHLVGWQTLGIIAIMDGVECIHSFGADFRDIRGFLIGDHSDMFNQKAELINQGSHFTFSQEDFLTSILPALTEVDTVVFIFTLDDNLAEVQTLVEQVKEKTSNIQALAHGTVGQSLPTPLKKLFPSIISITWPLLFFEYEGNFIQKFQHELSTKWVLNTVSTGAHVLLGKILQNHTLDLRIRNSKLFWRALSMLQRFSGQPKARCIESLLQAIHFPQPLSDDVRAAPISFHVQAADKKEQVIPIALLSLLFRCSIPEAQAHLAGAPSVCEAIRSALTGPGRKRNADALETLEPALP", "length": 641, "header": "tr|I3L883-1|I3L883_PIG Computationally mapped isoform of Glucokinase regulator OS=Sus scrofa OX=9823 GN=GCKR PE=1 SV=3 CANONICAL=A0A286ZZP4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "fructose-6-phosphate binding", "id": "GO:0070095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070095", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "intracellular glucose homeostasis", "id": "GO:0001678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001678", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "response to fructose", "id": "GO:0009750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009750", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "carbohydrate derivative metabolic process", "id": "GO:1901135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901135", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZZP4", "url": "https://www.uniprot.org/uniprot/A0A286ZZP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 505, "end_pos": 507 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }