{ "uniprot_canonical_ac": "A0A286ZP67-1", "uniprot_ac": "A0A286ZP67", "uniprot_id": "A0A286ZP67_PIG", "mass": { "chemical_mass": 89061.0, "monoisotopic_mass": 89061.0 }, "refseq": {}, "gene_names": [ { "name": "HNRNPU", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A286ZP67", "id": "A0A286ZP67" } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein U", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A286ZP67" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "common_name": "Pig" } ], "gene": [ { "name": "HNRNPU", "url": "https://www.uniprot.org/uniprot/A0A286ZP67", "locus": { "chromosome": "10", "start_pos": 17477902, "end_pos": 17497030, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010877", "url": "https://www.ensembl.org/id/ENSSSCG00000010877" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010877", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010877", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12884", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12884", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "F1S8L9", "url": "https://www.ebi.ac.uk/intact/interactors/id:F1S8L9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PHQFQQR", "url": "https://omabrowser.org/oma/group/PHQFQQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12381:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12381:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "http://pfam.xfam.org/family/PF00622", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "http://pfam.xfam.org/family/PF02037", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13671", "url": "http://pfam.xfam.org/family/PF13671", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-72203", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "A0A286ZJR3", "url": "https://www.uniprot.org/uniprot/A0A286ZJR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZJR3-1", "url": "https://www.uniprot.org/uniprot/A0A286ZJR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZP67-1", "url": "https://www.uniprot.org/uniprot/A0A286ZP67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVL0", "url": "https://www.uniprot.org/uniprot/A0A286ZVL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286ZVL0-1", "url": "https://www.uniprot.org/uniprot/A0A286ZVL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGD3", "url": "https://www.uniprot.org/uniprot/A0A5G2QGD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5G2QGD3-1", "url": "https://www.uniprot.org/uniprot/A0A5G2QGD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8L9", "url": "https://www.uniprot.org/uniprot/F1S8L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1S8L9-1", "url": "https://www.uniprot.org/uniprot/F1S8L9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAERSGAGLEQEAAAGGDEEEEEEEEEEEGIAALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGEEEEGAGDENGHGEQQPQPPAAPQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGIAFKISKEVLAERPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRGPVFPSRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY", "length": 806, "header": "tr|A0A286ZP67-1|A0A286ZP67_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein U OS=Sus scrofa OX=9823 GN=HNRNPU PE=1 SV=1 CANONICAL=A0A286ZP67-1" }, "isoforms": [ { "isoform_ac": "A0A286ZJR3-1", "url": "", "sequence": { "sequence": "MSSSPVNVKKLKAASEDENGDDQGFQEGEDELGEEEEGAGDENGHGEQQPQPPAAPQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGIAFKISKEVLAERPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRGPVFPSRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY", "length": 693, "header": "tr|A0A286ZJR3-1|A0A286ZJR3_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein U OS=Sus scrofa OX=9823 GN=HNRNPU PE=1 SV=2 CANONICAL=A0A286ZP67-1" }, "locus": { "chromosome": "10", "start_pos": 17496799, "end_pos": 17486279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000046854.3", "url": "https://www.ensembl.org/id/ENSSSCT00000046854.3" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000031714.2", "url": "https://www.ensembl.org/id/ENSSSCP00000031714.2" } ] } }, { "isoform_ac": "A0A286ZP67-1", "url": "", "sequence": { "sequence": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAERSGAGLEQEAAAGGDEEEEEEEEEEEGIAALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGEEEEGAGDENGHGEQQPQPPAAPQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGIAFKISKEVLAERPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRGPVFPSRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY", "length": 806, "header": "tr|A0A286ZP67-1|A0A286ZP67_PIG Isoform 1 of Heterogeneous nuclear ribonucleoprotein U OS=Sus scrofa OX=9823 GN=HNRNPU PE=1 SV=1 CANONICAL=A0A286ZP67-1" }, "locus": {} }, { "isoform_ac": "A0A286ZVL0-1", "url": "", "sequence": { "sequence": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAERSGAGLEQEAAAGGDEEEEEEEEEEEGIAALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGEEEEGAGDENGHGEQQPQPPAAPQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGDNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGIAFKISKEVLAERPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRGPVFPSRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY", "length": 744, "header": "tr|A0A286ZVL0-1|A0A286ZP67_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein U OS=Sus scrofa OX=9823 GN=HNRNPU PE=1 SV=2 CANONICAL=A0A286ZP67-1" }, "locus": {} }, { "isoform_ac": "A0A5G2QGD3-1", "url": "", "sequence": { "sequence": "KFILDMGKFAFDIIADNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGIAFKISKEVLAERPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRGPVFPSRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY", "length": 548, "header": "tr|A0A5G2QGD3-1|A0A5G2QGD3_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein U OS=Sus scrofa OX=9823 GN=HNRNPU PE=1 SV=1 CANONICAL=A0A286ZP67-1" }, "locus": {} }, { "isoform_ac": "F1S8L9-1", "url": "", "sequence": { "sequence": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAERSGAGLEQEAAAGGDEEEEEEEEEEEGIAALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGEEEEGAGDENGHGEQQPQPPAAPQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGIAFKISKEVLAERPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRGPVFPSRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGSVHVNVLCGRVKGPK", "length": 804, "header": "tr|F1S8L9-1|A0A286ZP67_PIG Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein U OS=Sus scrofa OX=9823 GN=HNRNPU PE=1 SV=3 CANONICAL=A0A286ZP67-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.", "journal": "PeerJ", "date": "2019", "authors": "Gilbert Donald G", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "reference": [ { "type": "PubMed", "id": "30723633", "url": "https://glygen.org/publication/PubMed/30723633" } ] } ], "pathway": [ { "id": "R-SSC-72163", "name": "mRNA Splicing - Major Pathway", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-SSC-72203", "name": "Processing of Capped Intron-Containing Pre-mRNA", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-72203", "resource": "Reactome", "description": "Processing of Capped Intron-Containing Pre-mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 20, "go_terms": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "snRNA binding", "id": "GO:0017069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017069", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "poly(G) binding", "id": "GO:0034046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034046", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "TFIIH-class transcription factor complex binding", "id": "GO:0001097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001097", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "poly(C) RNA binding", "id": "GO:0017130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017130", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain binding", "id": "GO:0099122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099122", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A286ZP67", "url": "https://www.uniprot.org/uniprot/A0A286ZP67" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": 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