{
    "bcoid": "GLY_000841",
    "title": "Dicty Glycohydrolases",
    "description": "The Dicty Glycohydrolases dataset contains a list of dicty [taxid:44689] glycohydrolases derived from ...",
    "filename": "dicty_protein_glycohydrolase.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Dictyostelium discoideum"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
            "Glycohydrolases"
        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ]
    },
    "minitable": {
        "content": [
            [
                "P13723-1...",
                "Dictyosteliu..."
            ],
            [
                "P34098-1...",
                "Dictyosteliu..."
            ]
        ],
        "headers": [
            "uniprotkb_ca...",
            "species..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "uniprotkb_canonical_ac"
                },
                {
                    "type": "string",
                    "label": "species"
                },
                {
                    "type": "string",
                    "label": "status"
                },
                {
                    "type": "string",
                    "label": "gene_symbol"
                },
                {
                    "type": "string",
                    "label": "uniprotkb_protein_name"
                },
                {
                    "type": "string",
                    "label": "ec_number"
                },
                {
                    "type": "string",
                    "label": "brenda_ec_number"
                },
                {
                    "type": "string",
                    "label": "cazy_gt_family"
                },
                {
                    "type": "string",
                    "label": "interpro_id"
                },
                {
                    "type": "string",
                    "label": "pfam_ac"
                },
                {
                    "type": "string",
                    "label": "go_molecular_function"
                }
            ],
            [
                "P13723-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "hexa1",
                "Beta-hexosaminidase subunit A1 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit A1) (N-acetyl-beta-glucosaminidase subunit A1)",
                "3.2.1.52",
                "",
                "GH20",
                "IPR025705|IPR015883|IPR017853|IPR029018|IPR029019",
                "PF00728|PF14845",
                "beta-N-acetylhexosaminidase activity [GO:0004563]| N-acetyl-beta-D-galactosaminidase activity [GO:0102148]"
            ],
            [
                "P34098-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manA",
                "Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Alpha-mannosidase A) [Cleaved into: Alpha-mannosidase 60 kDa subunit; Alpha-mannosidase 58 kDa subunit]",
                "3.2.1.24",
                "",
                "GH38",
                "IPR011013|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780",
                "PF09261|PF07748|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q556R7-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "cf50-1; cf50-2",
                "Counting factor 50 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 1) (GH family 25 lysozyme 1)",
                "3.2.1.17",
                "",
                "",
                "IPR002053|IPR017853",
                "PF01183",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q8T1G4-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "alyA",
                "Lysozyme A (EC 3.2.1.n3) (1,4-beta-N-acetylmuramidase A)",
                "3.2.1.n3",
                "",
                "",
                "",
                "",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q94502-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "modA",
                "Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha) (Protein post-translational modification mutant A)",
                "3.2.1.207",
                "3.2.1.207",
                "GH31",
                "IPR011013|IPR000322|IPR030458|IPR025887|IPR013780|IPR017853",
                "PF13802|PF01055",
                "alpha-glucosidase activity [GO:0090599]| carbohydrate binding [GO:0030246]| glucan 1,3-alpha-glucosidase activity [GO:0033919]"
            ],
            [
                "P10901-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "alfA",
                "Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase)",
                "3.2.1.51",
                "3.2.1.51",
                "GH29",
                "IPR016286|IPR031919|IPR000933|IPR018526|IPR013780|IPR017853",
                "PF01120|PF16757",
                "1,6-alpha-L-fucosidase activity [GO:0033938]| alpha-L-fucosidase activity [GO:0004560]"
            ],
            [
                "P22699-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "celA",
                "Endoglucanase (EC 3.2.1.4) (Cellulase) (Endo-1,4-beta-glucanase) (Spore germination protein 270-6)",
                "3.2.1.4",
                "",
                "CBM8|GH9",
                "IPR008928|IPR012341|IPR001701|IPR033126|IPR018221",
                "PF00759",
                "cellulase activity [GO:0008810]| cellulose binding [GO:0030248]"
            ],
            [
                "Q23892-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "gluA",
                "Lysosomal beta glucosidase (EC 3.2.1.21)",
                "3.2.1.21",
                "",
                "GH3",
                "IPR026891|IPR002772|IPR036881|IPR001764|IPR036962|IPR017853|IPR013783",
                "PF14310|PF00933|PF01915",
                "beta-glucosidase activity [GO:0008422]| scopolin beta-glucosidase activity [GO:0102483]"
            ],
            [
                "Q1ZXI8-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manE",
                "Alpha-mannosidase E (EC 3.2.1.24)",
                "3.2.1.24",
                "",
                "",
                "IPR011013|IPR011330|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780",
                "PF09261|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q54BL8-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Probable GH family 25 lysozyme 5 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 5)",
                "3.2.1.17",
                "",
                "",
                "IPR002053|IPR017853",
                "PF01183",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q54BQ8-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Probable GH family 25 lysozyme 4 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 4)",
                "3.2.1.17",
                "",
                "",
                "IPR002053|IPR017853",
                "PF01183",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q54GE1-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "glb1",
                "Beta-galactosidase 1 (EC 3.2.1.23) (Acid beta-galactosidase 1) (Lactase 1)",
                "3.2.1.23",
                "",
                "",
                "IPR026283|IPR008979|IPR031330|IPR019801|IPR001944|IPR017853",
                "PF01301",
                "beta-galactosidase activity [GO:0004565]"
            ],
            [
                "Q54K55-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "hexb1",
                "Beta-hexosaminidase subunit B1 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit B1) (N-acetyl-beta-glucosaminidase subunit B1)",
                "3.2.1.52",
                "",
                "",
                "IPR025705|IPR015883|IPR017853|IPR029018|IPR029019",
                "PF00728|PF14845",
                "beta-N-acetylhexosaminidase activity [GO:0004563]| N-acetyl-beta-D-galactosaminidase activity [GO:0102148]"
            ],
            [
                "Q54K56-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "hexb2",
                "Beta-hexosaminidase subunit B2 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit B2) (N-acetyl-beta-glucosaminidase subunit B2)",
                "3.2.1.52",
                "",
                "",
                "IPR025705|IPR015883|IPR017853|IPR029018|IPR029019",
                "PF00728|PF14845",
                "beta-N-acetylhexosaminidase activity [GO:0004563]| N-acetyl-beta-D-galactosaminidase activity [GO:0102148]"
            ],
            [
                "Q54KN4-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manF",
                "Alpha-mannosidase F (EC 3.2.1.24)",
                "3.2.1.24",
                "",
                "",
                "IPR011013|IPR011330|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995",
                "PF09261|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q54KX5-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "pgghg",
                "Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1)",
                "3.2.1.107",
                "",
                "",
                "IPR008928|IPR012341|IPR005195",
                "PF03632",
                "hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]| protein-glucosylgalactosylhydroxylysine glucosidase activity [GO:0047402]"
            ],
            [
                "Q54SC9-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "hexa2",
                "Beta-hexosaminidase subunit A2 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit A2) (N-acetyl-beta-glucosaminidase subunit A2)",
                "3.2.1.52",
                "",
                "",
                "IPR025705|IPR015883|IPR017853|IPR029018|IPR029019",
                "PF00728|PF14845",
                "beta-N-acetylhexosaminidase activity [GO:0004563]| N-acetyl-beta-D-galactosaminidase activity [GO:0102148]"
            ],
            [
                "Q54YC4-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manD",
                "Alpha-mannosidase D (EC 3.2.1.24)",
                "3.2.1.24",
                "",
                "",
                "IPR011013|IPR011330|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780",
                "PF09261|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q54YF7-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manB",
                "Alpha-mannosidase B (EC 3.2.1.24)",
                "3.2.1.24",
                "",
                "",
                "IPR011013|IPR041147|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780",
                "PF09261|PF17677|PF07748|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q556Y7-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "alyD-1; alyD-2",
                "Lysozyme D (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase D)",
                "3.2.1.17",
                "",
                "",
                "",
                "",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q55ER0-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manC",
                "Alpha-mannosidase C (EC 3.2.1.24)",
                "3.2.1.24",
                "",
                "",
                "IPR011013|IPR011330|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780",
                "PF09261|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q7KWM9-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "iunH",
                "Probable ribonucleoside hydrolase (EC 3.2.2.1) (EC 3.2.2.8)",
                "3.2.2.1|3.2.2.8",
                "",
                "",
                "IPR001910|IPR023186|IPR036452",
                "PF01156",
                "hydrolase activity, acting on glycosyl bonds [GO:0016798]| metal ion binding [GO:0046872]| purine nucleosidase activity [GO:0008477]| ribosylpyrimidine nucleosidase activity [GO:0050263]"
            ],
            [
                "Q7KWW8-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "ctbs1",
                "Probable di-N-acetylchitobiase 1 (EC 3.2.1.-)",
                "3.2.1.-",
                "",
                "",
                "IPR011583|IPR029070|IPR047898|IPR001223|IPR017853",
                "PF00704",
                "chitin binding [GO:0008061]| hydrolase activity, acting on glycosyl bonds [GO:0016798]"
            ],
            [
                "Q86KC1-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Probable GH family 25 lysozyme 2 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 2)",
                "3.2.1.17",
                "",
                "",
                "IPR002053|IPR017853",
                "PF01183",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q8T1G5-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "alyC",
                "Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C)",
                "3.2.1.17",
                "",
                "",
                "",
                "",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q8T1G6-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "alyB",
                "Lysozyme B (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase B)",
                "3.2.1.17",
                "",
                "",
                "",
                "",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q8T293-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "ctbs2",
                "Probable di-N-acetylchitobiase 2 (EC 3.2.1.-)",
                "3.2.1.-",
                "",
                "GH18",
                "IPR011583|IPR029070|IPR047898|IPR001223|IPR017853",
                "PF00704",
                "chitin binding [GO:0008061]| hydrolase activity, acting on glycosyl bonds [GO:0016798]"
            ],
            [
                "Q8T2I5-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Probable GH family 25 lysozyme 3 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 3)",
                "3.2.1.17",
                "",
                "",
                "IPR002053|IPR017853",
                "PF01183",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q54K67-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "manG",
                "Alpha-mannosidase G (EC 3.2.1.24)",
                "3.2.1.24",
                "",
                "",
                "IPR011013|IPR041147|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995",
                "PF09261|PF17677|PF07748|PF01074",
                "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]"
            ],
            [
                "Q54KF6-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Protein DDB_G0287365",
                "",
                "",
                "",
                "IPR019316",
                "PF10162",
                "hydrolase activity, acting on glycosyl bonds [GO:0016798]"
            ],
            [
                "Q54MV6-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "glb2",
                "Probable beta-galactosidase 2 (Lactase 2) (EC 3.2.1.23)",
                "3.2.1.23",
                "",
                "",
                "IPR008979|IPR031330|IPR019801|IPR001944|IPR017853",
                "PF01301",
                "beta-galactosidase activity [GO:0004565]"
            ],
            [
                "Q54QZ5-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "treh",
                "Trehalase (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase)",
                "3.2.1.28",
                "",
                "",
                "IPR008928|IPR012341|IPR001661",
                "PF01204",
                "alpha,alpha-trehalase activity [GO:0004555]"
            ],
            [
                "Q556F2-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Probable T4-type lysozyme 1 (EC 3.2.1.17) (Muramidase)",
                "3.2.1.17",
                "",
                "GH24",
                "IPR002196|IPR023346|IPR023347|IPR001165",
                "PF00959",
                "lysozyme activity [GO:0003796]"
            ],
            [
                "Q55B10-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "melA",
                "Probable alpha-galactosidase (EC 3.2.1.22) (Alpha-D-galactoside galactohydrolase) (Melibiase)",
                "3.2.1.22",
                "",
                "",
                "IPR013785|IPR002241|IPR013780|IPR017853|IPR041233",
                "PF16499|PF17801",
                "alpha-galactosidase activity [GO:0004557]"
            ],
            [
                "Q86AA1-1",
                "Dictyostelium discoideum (Social amoeba)",
                "reviewed",
                "",
                "Probable T4-type lysozyme 2 (EC 3.2.1.17) (Muramidase)",
                "3.2.1.17",
                "",
                "GH24",
                "IPR002196|IPR023346|IPR023347|IPR001165",
                "PF00959",
                "lysozyme activity [GO:0003796]"
            ]
        ]
    },
    "readme": "Name\n   - Dicty Glycohydrolases\n\nVersion\n   - v-2.4.1\n\nCreated on\n  - \n\nModified on\n   - 2024-01-09T04:38:49\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Luke Johnson [luke.johnson@email.gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Cyrus Au-Yeung [cyruschauyeung@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n   - \n\nChecksum\n   - \n\nUsability Domain\n   - The Dicty Glycohydrolases dataset contains a list of dicty [taxid:44689] glycohydrolases derived from UniProtKB database using advanced search and other databases including CAZy, InterPro and Pfam. . If you use this dataset please provide proper attribution to UniProtKB and GlyGen\n\nDescription Domain\n   Keywords\n   - glycohydrolase\n   - glycosidase\n   - EC Number\n   - CAZy\n\n   Pipeline Steps\n   - Step-1: The script maps and replaces the UniProtKb accession to the UniProtKB canonical accession\n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: dicty_protein_glycohydrolase.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/compiled/dicty_protein_glycohydrolase.csv\n      Name: dicty_protein_masterlist.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/dicty_protein_masterlist.csv\n   Output Subdomain\n      Name: dicty_protein_glycohydrolase.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/dicty_protein_glycohydrolase.csv\n      Name: dicty_protein_glycohydrolase.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/dicty_protein_glycohydrolase.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\n     Description: \"\"\n      Unique Values: \"35\"\n      Name: \"species\"\n     Description: \"Species of the protein.\"\n      Unique Values: \"1\"\n      Name: \"status\"\n     Description: \"Status of the protein record in UniProtKB database that can be reviewed for UniProtKB/Swiss-Prot entry or unreviewed for UniProtKB/TrEMBL entry\"\n      Unique Values: \"1\"\n      Name: \"gene_symbol\"\n     Description: \"\"Official gene name/symbol assigned to the gene. Human gene names/symbols are approved by the HUGO Gene Nomenclature Committee (HGNC)\"\n      Unique Values: \"29\"\n      Name: \"uniprotkb_protein_name\"\n     Description: \"Name of the protein in UniProtKB database\"\n      Unique Values: \"35\"\n      Name: \"ec_number\"\n     Description: \"Enzyme Commision number assigned to an enzyme by Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB)\"\n      Unique Values: \"15\"\n      Name: \"brenda_ec_number\"\n     Description: \"Enzyme Commission (EC) number assigned to enzyme in BRENDA database\"\n      Unique Values: \"3\"\n      Name: \"cazy_gt_family\"\n     Description: \"The Family assigned to glycosyltransferase in the CAZy (Carbohydrate-Active enZYmes) database\"\n      Unique Values: \"9\"\n      Name: \"interpro_id\"\n     Description: \"InterPro Identifier\"\n      Unique Values: \"21\"\n      Name: \"pfam_ac\"\n     Description: \"Accession assigned to the protein family in the Pfam database\"\n      Unique Values: \"18\"\n      Name: \"go_molecular_function\"\n     Description: \"\"The elemental activities of a gene product at the molecular level\"\n      Unique Values: \"14\"",
    "downloadurl": "/ln2data/releases/data/v-2.4.1/reviewed/dicty_protein_glycohydrolase.csv"
}
