{ "bcoid": "GLY_000355", "title": "HCV1a Protein Citations (UniProtKB)", "description": "The Hepatitis C virus (genotype 1a, isolate H) Protein Citations dataset contains publication information ...", "filename": "hcv1a_protein_citations_uniprotkb.csv", "filetype": "csv", "categories": { "species": [ "Hepatitis c virus (isolate h)" ], "molecule": [ "Protein" ], "tag": [ "Protein Citations" ], "file_type": [ "csv" ], "status": [ "Reviewed" ], "scope": [ "internal" ] }, "minitable": { "content": [ [ "P27958-1...", "Both NS3 and..." ], [ "P27958-1...", "Hepatitis C ..." ] ], "headers": [ "uniprotkb_ca...", "title..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "title" }, { "type": "string", "label": "journal_name" }, { "type": "string", "label": "publication_date" }, { "type": "string", "label": "authors" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "src_xref_key" }, { "type": "string", "label": "src_xref_id" } ], [ "P27958-1", "Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins.", "Journal of virology", "1994 Jun", "Failla C, Tomei L, De Francesco R", "protein_xref_pubmed", "8189513", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C Virus Modulates Solute carrier family 3 member 2 for Viral Propagation.", "Scientific reports", "2018-10-19", "Nguyen Ngan N T, Lim Yun-Sook, Nguyen Lap P, Tran Si C, Luong Trang T D, Nguyen Tram T T, Pham Hang T, Mai Han N, Choi Jae-Woong, Han Sang-Seop, Hwang Soon B", "protein_xref_pubmed", "30341327", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease.", "Journal of virology", "2011 Jul", "Romano KP, Laine JM, Deveau LM, Cao H, Massi F, Schiffer CA", "protein_xref_pubmed", "21507982", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Induction of FAS ligand expression in a human hepatoblastoma cell line by HCV core protein.", "Virus research", "2003-11", "Ruggieri A, Murdolo M, Rapicetta M", "protein_xref_pubmed", "14602201", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production.", "Journal of leukocyte biology", "2007-12", "Waggoner Stephen N, Hall Caroline H T, Hahn Young S", "protein_xref_pubmed", "17881511", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "RNA chaperoning and intrinsic disorder in the core proteins of Flaviviridae.", "Nucleic acids research", "2008-02", "Ivanyi-Nagy Roland, Lavergne Jean-Pierre, Gabus Caroline, Ficheux Damien, Darlix Jean-Luc", "protein_xref_pubmed", "18033802", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Mutations in the STAT1\u2011interacting domain of the hepatitis C virus core protein modulate the response to antiviral therapy.", "Molecular medicine reports", "2013-08", "Anjum Sadia, Afzal Muhammad Sohail, Ahmad Tahir, Aslam Baber, Waheed Yasir, Shafi Talha, Qadri Ishtiaq", "protein_xref_pubmed", "23799612", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation.", "The Journal of clinical investigation", "2000-11", "Kittlesen D J, Chianese-Bullock K A, Yao Z Q, Braciale T J, Hahn Y S", "protein_xref_pubmed", "11086025", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.", "Journal of virology", "2011-02", "Stapleford Kenneth A, Lindenbach Brett D", "protein_xref_pubmed", "21147927", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "A second hepatitis C virus-encoded proteinase.", "Proceedings of the National Academy of Sciences of the United States of America", "1993 Nov 15", "Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM", "protein_xref_pubmed", "8248148", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry.", "Hepatology (Baltimore, Md.)", "2014-03", "Douam Florian, Dao Thi Viet Loan, Maurin Guillemette, Fresquet Judith, Mompelat Dimitri, Zeisel Mirjam B, Baumert Thomas F, Cosset Fran\u00e7ois-Lo\u00efc, Lavillette Dimitri", "protein_xref_pubmed", "24038151", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Characterization of functional hepatitis C virus envelope glycoproteins.", "Journal of virology", "2004 Mar", "Op De Beeck A, Voisset C, Bartosch B, Ciczora Y, Cocquerel L, Keck Z, Foung S, Cosset FL, Dubuisson J", "protein_xref_pubmed", "14990718", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Entry of hepatitis C virus pseudotypes into primary human hepatocytes by clathrin-dependent endocytosis.", "The Journal of general virology", "2006-09", "Codran Audrey, Royer Cathy, Jaeck Daniel, Bastien-Valle Mich\u00e8le, Baumert Thomas F, Kieny Marie Paule, Pereira Carlos Augusto, Martin Jean-Pierre", "protein_xref_pubmed", "16894197", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The association of hepatitis C virus glycoproteins with apolipoproteins E and B early in assembly is conserved in lipoviral particles.", "The Journal of biological chemistry", "2014-07-04", "Boyer Audrey, Dumans Am\u00e9lie, Beaumont Elodie, Etienne Lo\u00efc, Roingeard Philippe, Meunier Jean-Christophe", "protein_xref_pubmed", "24838241", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Human occludin is a hepatitis C virus entry factor required for infection of mouse cells.", "Nature", "2009-02-12", "Ploss Alexander, Evans Matthew J, Gaysinskaya Valeriya A, Panis Maryline, You Hana, de Jong Ype P, Rice Charles M", "protein_xref_pubmed", "19182773", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor.", "The Journal of biological chemistry", "2003-10-24", "Bartosch Birke, Vitelli Alessandra, Granier Christelle, Goujon Caroline, Dubuisson Jean, Pascale Simona, Scarselli Elisa, Cortese Riccardo, Nicosia Alfredo, Cosset Fran\u00e7ois-Lo\u00efc", "protein_xref_pubmed", "12913001", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.", "PLoS pathogens", "2018-03", "Douam Florian, Fusil Floriane, Enguehard Margot, Dib Linda, Nadalin Francesca, Schwaller Lo\u00efc, Hrebikova Gabriela, Mancip Jimmy, Mailly Laurent, Montserret Roland, Ding Qiang, Maisse Carine, Carlot Emilie, Xu Ke, Verhoeyen Els, Baumert Thomas F, Ploss Alexander, Carbone Alessandra, Cosset Fran\u00e7ois-Lo\u00efc, Lavillette Dimitri", "protein_xref_pubmed", "29505618", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Regulation of Apolipoprotein E Trafficking by Hepatitis C Virus-Induced Autophagy.", "Journal of virology", "2018-07-15", "Kim Ja Yeon, Ou Jing-Hsiung James", "protein_xref_pubmed", "29695434", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus.", "Proceedings of the National Academy of Sciences of the United States of America", "2004-09-28", "Cormier Emmanuel G, Durso Robert J, Tsamis Fotini, Boussemart Lise, Manix Catherine, Olson William C, Gardner Jason P, Dragic Tatjana", "protein_xref_pubmed", "15371595", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission.", "Journal of virology", "2017-07-01", "Fan Huahao, Qiao Luhua, Kang Kyung-Don, Fan Junfen, Wei Wensheng, Luo Guangxiang", "protein_xref_pubmed", "28404852", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Apolipoprotein E likely contributes to a maturation step of infectious hepatitis C virus particles and interacts with viral envelope glycoproteins.", "Journal of virology", "2014-11", "Lee Ji-Young, Acosta Eliana G, Stoeck Ina Karen, Long Gang, Hiet Marie-Sophie, Mueller Birthe, Fackler Oliver T, Kallis Stephanie, Bartenschlager Ralf", "protein_xref_pubmed", "25122793", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry.", "Journal of virology", "2012-10", "Diao Jingyu, Pantua Homer, Ngu Hai, Komuves Laszlo, Diehl Lauri, Schaefer Gabriele, Kapadia Sharookh B", "protein_xref_pubmed", "22855500", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.", "The EMBO journal", "2002-10-01", "Scarselli Elisa, Ansuini Helenia, Cerino Raffaele, Roccasecca Rosa Maria, Acali Stefano, Filocamo Gessica, Traboni Cinzia, Nicosia Alfredo, Cortese Riccardo, Vitelli Alessandra", "protein_xref_pubmed", "12356718", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The membrane-active regions of the hepatitis C virus E1 and E2 envelope glycoproteins.", "Biochemistry", "2006-03-21", "P\u00e9rez-Berna Ana J, Moreno Miguel R, Guill\u00e9n Jaime, Bernabeu Angela, Villala\u00edn Jos\u00e9", "protein_xref_pubmed", "16533059", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Fusogenic properties of the ectodomains of hepatitis C virus envelope proteins.", "The FEBS journal", "2014-06", "Tello Daniel, Rodr\u00edguez-Rodr\u00edguez Mar, Ortega Sara, Lombana Laura, Y\u00e9lamos Bel\u00e9n, G\u00f3mez-Guti\u00e9rrez Juli\u00e1n, Peterson Darrell L, Gavilanes Francisco", "protein_xref_pubmed", "24698129", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.", "The Journal of biological chemistry", "2012 Sep 7", "Dao Thi VL, Granier C, Zeisel MB, Guerin M, Mancip J, Granio O, Penin F, Lavillette D, Bartenschlager R, Baumert TF, Cosset FL, Dreux M", "protein_xref_pubmed", "22767607", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "CD81-dependent binding of hepatitis C virus E1E2 heterodimers.", "Journal of virology", "2003-10", "Cocquerel Laurence, Kuo Chiung-Chi, Dubuisson Jean, Levy Shoshana", "protein_xref_pubmed", "12970454", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Claudin association with CD81 defines hepatitis C virus entry.", "The Journal of biological chemistry", "2010 Jul 2", "Harris HJ, Davis C, Mullins JG, Hu K, Goodall M, Farquhar MJ, Mee CJ, McCaffrey K, Young S, Drummer H, Balfe P, McKeating JA", "protein_xref_pubmed", "20375010", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride.", "FEBS letters", "2004-01-16", "Premkumar A, Wilson L, Ewart G D, Gage P W", "protein_xref_pubmed", "14741348", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production.", "PLoS pathogens", "2010-09-02", "Wozniak Ann L, Griffin Stephen, Rowlands David, Harris Mark, Yi MinKyung, Lemon Stanley M, Weinman Steven A", "protein_xref_pubmed", "20824094", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus induces interleukin-1\u03b2 (IL-1\u03b2)/IL-18 in circulatory and resident liver macrophages.", "Journal of virology", "2013-11", "Shrivastava Shubham, Mukherjee Anupam, Ray Ranjit, Ray Ratna B", "protein_xref_pubmed", "24006444", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus p7 induces mitochondrial depolarization of isolated liver mitochondria.", "Molecular medicine reports", "2017-12", "You Deok-Gyun, Lee Hye-Ra, Kim Won-Ki, Kim Hyung Jung, Lee Gi Young, Yoo Young Do", "protein_xref_pubmed", "29039530", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus p7 mediates membrane-to-membrane adhesion.", "Biochimica et biophysica acta", "2016-09", "Lee Gi Young, Lee Sora, Lee Hye-Ra, Yoo Young Do", "protein_xref_pubmed", "27320856", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives.", "Proceedings of the National Academy of Sciences of the United States of America", "2003-05-13", "Pavlovi\u0107 Davor, Neville David C A, Argaud Olivier, Blumberg Baruch, Dwek Raymond A, Fischer Wolfgang B, Zitzmann Nicole", "protein_xref_pubmed", "12719519", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.", "Journal of virology", "2020 Feb 14", "Nguyen LP, Tran SC, Suetsugu S, Lim YS, Hwang SB", "protein_xref_pubmed", "31801866", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis.", "The Journal of biological chemistry", "2010-10-22", "Harrus D\u00e9borah, Ahmed-El-Sayed Neveen, Simister Philip C, Miller Steve, Triconnet Martine, Hagedorn Curt H, Mahias Kathleen, Rey F\u00e9lix A, Astier-Gin Th\u00e9r\u00e8se, Bressanelli St\u00e9phane", "protein_xref_pubmed", "20729191", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.", "Nature", "2023-07", "Sherwood Anna V, Rivera-Rangel Lizandro R, Ryberg Line A, Larsen Helena S, Anker Klara M, Costa Rui, V\u00e5gb\u00f8 Cathrine B, Jakljevi\u010d Eva, Pham Long V, Fernandez-Antunez Carlota, Indrisiunaite Gabriele, Podolska-Charlery Agnieszka, Grothen Julius E R, Langvad Nicklas W, Fossat Nicolas, Offersgaard Anna, Al-Chaer Amal, Nielsen Louise, Ku\u015bnierczyk Anna, S\u00f8lund Christina, Weis Nina, Gottwein Judith M, Holmbeck Kenn, Bottaro Sandro, Ramirez Santseharay, Bukh Jens, Scheel Troels K H, Vinther Jeppe", "protein_xref_pubmed", "37407817", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Interferon alpha (IFN\u03b1)-induced TRIM22 interrupts HCV replication by ubiquitinating NS5A.", "Cellular & molecular immunology", "2016-01", "Yang Chen, Zhao Xinhao, Sun Dakang, Yang Leilei, Chong Chang, Pan Yu, Chi Xiumei, Gao Yanhang, Wang Moli, Shi Xiaodong, Sun Haibo, Lv Juan, Gao Yuanda, Zhong Jin, Niu Junqi, Sun Bing", "protein_xref_pubmed", "25683609", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity.", "Gastroenterology", "2006-03", "Nanda Santosh K, Herion David, Liang T Jake", "protein_xref_pubmed", "16530520", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins.", "Journal of virology", "2010-12", "Hwang Jungwook, Huang Luyun, Cordek Daniel G, Vaughan Robert, Reynolds Shelley L, Kihara George, Raney Kevin D, Kao C Cheng, Cameron Craig E", "protein_xref_pubmed", "20926572", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C Virus Exploits Death Receptor 6-mediated Signaling Pathway to Facilitate Viral Propagation.", "Scientific reports", "2017 Jul 25", "Luong TTD, Tran GVQ, Shin DJ, Lim YS, Hwang SB", "protein_xref_pubmed", "28743875", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Molecular and structural characterization of the domain 2 of hepatitis C virus non-structural protein 5A.", "Molecules and cells", "2006-08-31", "Liang Yu, Kang Cong Bao, Yoon Ho Sup", "protein_xref_pubmed", "16951545", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein.", "Scientific reports", "2016-08-31", "Wang Shanshan, Chen Yongzhi, Li Chunfeng, Wu Yaoxing, Guo Lei, Peng Changwei, Huang Yueping, Cheng Genhong, Qin F Xiao-Feng", "protein_xref_pubmed", "27578425", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity.", "Journal of hepatology", "2013-07", "Ding Qiang, Cao Xuezhi, Lu Jie, Huang Bing, Liu Yong-Jun, Kato Nobuyuki, Shu Hong-Bing, Zhong Jin", "protein_xref_pubmed", "23542348", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Palmitoylation and polymerization of hepatitis C virus NS4B protein.", "Journal of virology", "2006 Jun", "Yu GY, Lee KJ, Gao L, Lai MM", "protein_xref_pubmed", "16731940", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway.", "PLoS pathogens", "2018-05", "Liang Yisha, Cao Xuezhi, Ding Qiang, Zhao Yanan, He Zhenliang, Zhong Jin", "protein_xref_pubmed", "29782532", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex.", "Journal of virology", "2002-06", "Egger Denise, W\u00f6lk Benno, Gosert Rainer, Bianchi Leonardo, Blum Hubert E, Moradpour Darius, Bienz Kurt", "protein_xref_pubmed", "12021330", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Kinetic and structural analyses of hepatitis C virus polyprotein processing.", "Journal of virology", "1994 Aug", "Bartenschlager R, Ahlborn-Laake L, Mous J, Jacobsen H", "protein_xref_pubmed", "8035505", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.", "Nature", "2005 Oct 20", "Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J", "protein_xref_pubmed", "16177806", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Periodic cycles of RNA unwinding and pausing by hepatitis C virus NS3 helicase.", "Nature", "2004-07-22", "Serebrov Victor, Pyle Anna Marie", "protein_xref_pubmed", "15269774", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Single-base pair unwinding and asynchronous RNA release by the hepatitis C virus NS3 helicase.", "Science (New York, N.Y.)", "2011-09-23", "Cheng Wei, Arunajadai Srikesh G, Moffitt Jeffrey R, Tinoco Ignacio, Bustamante Carlos", "protein_xref_pubmed", "21940894", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites.", "Journal of virology", "1993 May", "Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM", "protein_xref_pubmed", "8386278", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF.", "Proceedings of the National Academy of Sciences of the United States of America", "2005 Feb 22", "Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr, Lemon SM", "protein_xref_pubmed", "15710891", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.", "Proceedings of the National Academy of Sciences of the United States of America", "2005 Dec 6", "Li XD, Sun L, Seth RB, Pineda G, Chen ZJ", "protein_xref_pubmed", "16301520", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "pH-dependent conformational changes in the HCV NS3 protein modulate its ATPase and helicase activities.", "PloS one", "2014", "Ventura Gustavo Tavares, Costa Emmerson Corr\u00eaa Brasil da, Capaccia Anne Miranda, Mohana-Borges Ronaldo", "protein_xref_pubmed", "25551442", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway.", "Journal of virology", "2016 Aug 1", "Xue B, Yang D, Wang J, Xu Y, Wang X, Qin Y, Tian R, Chen S, Xie Q, Liu N, Zhu H", "protein_xref_pubmed", "27194766", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylation.", "The Journal of biological chemistry", "2004 Nov 26", "Kim SJ, Kim JH, Kim YG, Lim HS, Oh JW", "protein_xref_pubmed", "15364941", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Mass spectrometric characterization of glycosylation of hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans.", "Journal of the American Society for Mass Spectrometry", "2008 Mar", "Iacob RE, Perdivara I, Przybylski M, Tomer KB", "protein_xref_pubmed", "18187336", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Palmitoylation of Hepatitis C Virus NS2 Regulates Its Subcellular Localization and NS2-NS3 Autocleavage.", "Journal of virology", "2019 Dec 12", "Wu MJ, Shanmugam S, Welsch C, Yi M", "protein_xref_pubmed", "31597774", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Analysis of the processing and transmembrane topology of the E2p7 protein of hepatitis C virus.", "The Journal of general virology", "2005 Mar", "Isherwood BJ, Patel AH", "protein_xref_pubmed", "15722527", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Regulation of hepatitis C virus polyprotein processing by signal peptidase involves structural determinants at the p7 sequence junctions.", "The Journal of biological chemistry", "2004 Oct 1", "Carrere-Kremer S, Montpellier C, Lorenzo L, Brulin B, Cocquerel L, Belouzard S, Penin F, Dubuisson J", "protein_xref_pubmed", "15247249", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Expression and identification of hepatitis C virus polyprotein cleavage products.", "Journal of virology", "1993 Mar", "Grakoui A, Wychowski C, Lin C, Feinstone SM, Rice CM", "protein_xref_pubmed", "7679746", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.", "Cell", "1996 Oct 18", "Kim JL, Morgenstern KA, Lin C, Fox T, Dwyer MD, Landro JA, Chambers SP, Markland W, Lepre CA, O'Malley ET, Harbeson SL, Rice CM, Murcko MA, Caron PR, Thomson JA", "protein_xref_pubmed", "8861917", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.", "Nature", "2006 Aug 17", "Lorenz IC, Marcotrigiano J, Dentzer TG, Rice CM", "protein_xref_pubmed", "16862121", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus E2 envelope glycoprotein core structure.", "Science (New York, N.Y.)", "2013 Nov 29", "Kong L, Giang E, Nieusma T, Kadam RU, Cogburn KE, Hua Y, Dai X, Stanfield RL, Burton DR, Ward AB, Wilson IA, Law M", "protein_xref_pubmed", "24288331", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Analysis of the glycosylation sites of hepatitis C virus (HCV) glycoprotein E1 and the influence of E1 glycans on the formation of the HCV glycoprotein complex.", "The Journal of general virology", "1999 Apr", "Meunier JC, Fournillier A, Choukhi A, Cahour A, Cocquerel L, Dubuisson J, Wychowski C", "protein_xref_pubmed", "10211957", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Identification of the major phosphorylation site of the hepatitis C virus H strain NS5A protein as serine 2321.", "The Journal of biological chemistry", "1999 Sep 24", "Reed KE, Rice CM", "protein_xref_pubmed", "10488152", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Role of conserved cysteine residues in hepatitis C virus glycoprotein e2 folding and function.", "Journal of virology", "2012 Apr", "McCaffrey K, Boo I, Tewierek K, Edmunds ML, Poumbourios P, Drummer HE", "protein_xref_pubmed", "22278231", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences.", "Proceedings of the National Academy of Sciences of the United States of America", "2003 Sep 30", "Sakai A, Claire MS, Faulk K, Govindarajan S, Emerson SU, Purcell RH, Bukh J", "protein_xref_pubmed", "14504405", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation.", "PLoS ONE", "2019", "Wang M, Wang Y, Liu Y, Wang H, Xin X, Li J, Hao Y, Han L, Yu F, Zheng C, Shen C", "protein_xref_pubmed", "31344133", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein.", "Science", "1999", "Taylor D R, Shi S T, Romano P R, Barber G N, Lai M M", "protein_xref_pubmed", "10390359", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylation.", "J. Biol. Chem.", "2004", "Kim SJ, Kim JH, Kim YG, Lim HS, Oh JW", "protein_xref_pubmed", "15364941", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity.", "Proc. Natl. Acad. Sci. U.S.A.", "2005", "Li XD, Sun L, Seth RB, Pineda G, Chen ZJ", "protein_xref_pubmed", "16301520", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus NS5A protein modulates transcription through a novel cellular transcription factor SRCAP.", "J. Biol. Chem.", "2000", "Ghosh AK, Majumder M, Steele R, Yaciuk P, Chrivia J, Ray R, Ray RB", "protein_xref_pubmed", "10702287", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Identification of a novel protein binding to hepatitis C virus core protein.", "J. Gastroenterol. Hepatol.", "2009", "Chen YR, Chen TY, Zhang SL, Lin SM, Zhao YR, Ye F, Zhang X, Shi L, Dang SS, Liu M", "protein_xref_pubmed", "19486448", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Apolipoprotein E likely contributes to a maturation step of infectious hepatitis C virus particles and interacts with viral envelope glycoproteins.", "J. Virol.", "2014", "Lee Ji-Young, Acosta Eliana G, Stoeck Ina Karen, Long Gang, Hiet Marie-Sophie, Mueller Birthe, Fackler Oliver T, Kallis Stephanie, Bartenschlager Ralf", "protein_xref_pubmed", "25122793", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.", "Nature", "2005", "Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J", "protein_xref_pubmed", "16177806", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.", "EMBO J.", "2002", "Scarselli Elisa, Ansuini Helenia, Cerino Raffaele, Roccasecca Rosa Maria, Acali Stefano, Filocamo Gessica, Traboni Cinzia, Nicosia Alfredo, Cortese Riccardo, Vitelli Alessandra", "protein_xref_pubmed", "12356718", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity.", "J. Hepatol.", "2013", "Ding Qiang, Cao Xuezhi, Lu Jie, Huang Bing, Liu Yong-Jun, Kato Nobuyuki, Shu Hong-Bing, Zhong Jin", "protein_xref_pubmed", "23542348", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication.", "J. Virol.", "2007", "Kim Chon Saeng, Seol Su Kyoung, Song Ok-Kyu, Park Ji Hoon, Jang Sung Key", "protein_xref_pubmed", "17229681", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation.", "J. Clin. Invest.", "2000", "Kittlesen D J, Chianese-Bullock K A, Yao Z Q, Braciale T J, Hahn Y S", "protein_xref_pubmed", "11086025", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "The SH3 binding motif of HCV NS5A protein interacts with Bin1 and is important for apoptosis and infectivity.", "Gastroenterology", "2006", "Nanda Santosh K, Herion David, Liang T Jake", "protein_xref_pubmed", "16530520", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production.", "J. Leukoc. Biol.", "2007", "Waggoner Stephen N, Hall Caroline H T, Hahn Young S", "protein_xref_pubmed", "17881511", "protein_xref_uniprotkb", "P27958" ], [ "P27958-1", "Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.", "J. Virol.", "2005", "Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y", "protein_xref_pubmed", "16227268", "protein_xref_uniprotkb", "P27958" ] ] }, "readme": "Name\n - HCV1a Protein Citations (UniProtKB)\n\nVersion\n - v-2.4.1\n\nCreated on\n - 2020-03-13T11:25:59.634509\n\nModified on\n - 2022-09-26T09:05:27.741145\n\nCreated by\n - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Luke Johnson [luke.johnson@email.gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Cyrus Au-Yeung [cyruschauyeung@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n - Maria Martin [martin@ebi.ac.uk], Preethi Vasudev [pvasudev@ebi.ac.uk]\n\nChecksum\n - \n\nUsability Domain\n - The Hepatitis C virus (genotype 1a, isolate H) Protein Citations dataset contains publication information for hcv1a [taxid:11108] UniProtKB accessions that includes PMID, journal name, date and author and title. Publications of large scale studies, and high frequency publications pertaining to genome sequencing, cDNA, chromosomes have been filtered out as per https://data.glygen.org/ln2data/releases/data/v-1.12.3/compiled/hcv1a_protein_blacklisted_pmids_uniprotkb.csv. The dataset is derived from 2019-05 UniProt release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen\n\nDescription Domain\n Keywords\n - publications\n - PMID\n - journal\n - citations\n - authors\n - UniProtKB\n - PubMed\n\n Pipeline Steps\n - Step-1: The script loads the UniProtKB publication data from the triplestore containing triples from nt file to retrieve the publication information associated with the UniProtKB accession and maps it to the UniProtKB canonical accessions. The script also filters out publications of large scale studies, and high frequency publications pertaining to DNA sequencing, cDNA, chromosomes using blacklisted PMIDs file.\n\nExecution Domain\n Scripts - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: hcv1a_protein_function_uniprotkb.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/hcv1a_protein_function_uniprotkb.csv\n Name: hcv1a_protein_ptm_annotation_uniprotkb.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/hcv1a_protein_ptm_annotation_uniprotkb.csv\n Name: hcv1a_protein_site_annotation_uniprotkb.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/hcv1a_protein_site_annotation_uniprotkb.csv\n Name: uniprot-proteome-hepatitis-c-virus-1a.nt\n URI: https:/data.glygen.org/ln2downloads/ebi/2024_02_19/uniprot-proteome-hepatitis-c-virus-1a.nt\n Output Subdomain\n Name: hcv1a_protein_citations_uniprotkb.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/hcv1a_protein_citations_uniprotkb.csv\n Name: hcv1a_protein_citations_uniprotkb.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/hcv1a_protein_citations_uniprotkb.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"title\"\n Description: \"Title of the published article in the journal\"\n Unique Values: \"118\"\n Name: \"journal_name\"\n Description: \"The name of the journal in which the article is published\"\n Unique Values: \"50\"\n Name: \"publication_date\"\n Description: \"Contains the full date on which the issue of the journal was published. Sourced from MEDLINE/PubMed data element(fields) description.\"\n Unique Values: \"90\"\n Name: \"authors\"\n Description: \"NA\"\n Unique Values: \"117\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"1\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"118\"\n Name: \"src_xref_key\"\n Description: \"Source Xref key\"\n Unique Values: \"1\"\n Name: \"src_xref_id\"\n Description: \"Source X-ref ID\"\n Unique Values: \"1\"", "downloadurl": "/ln2data/releases/data/v-2.4.1/reviewed/hcv1a_protein_citations_uniprotkb.csv" }