{
    "bcoid": "GLY_000035",
    "title": "Human Protein Citations (UniProtKB)",
    "description": "The Human Protein Citations dataset contains publication information for human [taxid:9606] UniProtKB ...",
    "filename": "human_protein_citations_uniprotkb.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Homo sapiens"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
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        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ]
    },
    "minitable": {
        "content": [
            [
                "P30613-1...",
                "Structure an..."
            ],
            [
                "P23919-1...",
                "Structures o..."
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        "headers": [
            "uniprotkb_ca...",
            "title..."
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            "20%"
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                "P30613-1",
                "Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia.",
                "The Journal of biological chemistry",
                "2002 Jun 28",
                "Valentini G, Chiarelli LR, Fortin R, Dolzan M, Galizzi A, Abraham DJ, Wang C, Bianchi P, Zanella A, Mattevi A",
                "protein_xref_pubmed",
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                "P30613"
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            [
                "P23919-1",
                "Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.",
                "Biochemistry",
                "2003-03-11",
                "Ostermann Nils, Segura-Pe\u00f1a Dario, Meier Chris, Veit Thomas, Monnerjahn Christian, Konrad Manfred, Lavie Arnon",
                "protein_xref_pubmed",
                "12614151",
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                "P23919"
            ],
            [
                "P23919-1",
                "Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth.",
                "DNA and cell biology",
                "1994 May",
                "Huang SH, Tang A, Drisco B, Zhang SQ, Seeger R, Li C, Jong A",
                "protein_xref_pubmed",
                "8024690",
                "protein_xref_uniprotkb",
                "P23919"
            ],
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                "P23919-1",
                "Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia.",
                "The Journal of biological chemistry",
                "1977 Aug 25",
                "Lee LS, Cheng Y",
                "protein_xref_pubmed",
                "18469",
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                "P23919"
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            [
                "P23919-1",
                "Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast.",
                "Nucleic acids research",
                "1991 Feb 25",
                "Su JY, Sclafani RA",
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                "2017365",
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                "P23919"
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            [
                "P23919-1",
                "DTYMK is essential for genome integrity and neuronal survival.",
                "Acta neuropathologica",
                "2022 Feb",
                "Vanoevelen JM, Bierau J, Grashorn JC, Lambrichs E, Kamsteeg EJ, Bok LA, Wevers RA, van der Knaap MS, Bugiani M, Frisk JH, Colnaghi R, O'Driscoll M, Hellebrekers DMEI, Rodenburg R, Ferreira CR, Brunner HG, van den Wijngaard A, Abdel-Salam GMH, Wang L, Stumpel CTRM",
                "protein_xref_pubmed",
                "34918187",
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                "P23919"
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                "Q8NHX9-1",
                "Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.",
                "Science (New York, N.Y.)",
                "2015 Feb 27",
                "Sakurai Y, Kolokoltsov AA, Chen CC, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA",
                "protein_xref_pubmed",
                "25722412",
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                "Q8NHX9"
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                "Q8NHX9-1",
                "Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV.",
                "Nature communications",
                "2020 Mar 27",
                "Ou X, Liu Y, Lei X, Li P, Mi D, Ren L, Guo L, Guo R, Chen T, Hu J, Xiang Z, Mu Z, Chen X, Chen J, Hu K, Jin Q, Wang J, Qian Z",
                "protein_xref_pubmed",
                "32221306",
                "protein_xref_uniprotkb",
                "Q8NHX9"
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                "Q8NHX9-1",
                "Two newly identified genetic determinants of pigmentation in Europeans.",
                "Nature genetics",
                "2008 Jul",
                "Sulem P, Gudbjartsson DF, Stacey SN, Helgason A, Rafnar T, Jakobsdottir M, Steinberg S, Gudjonsson SA, Palsson A, Thorleifsson G, Palsson S, Sigurgeirsson B, Thorisdottir K, Ragnarsson R, Benediktsdottir KR, Aben KK, Vermeulen SH, Goldstein AM, Tucker MA, Kiemeney LA, Olafsson JH, Gulcher J, Kong A, Thorsteinsdottir U, Stefansson K",
                "protein_xref_pubmed",
                "18488028",
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                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling.",
                "The Journal of cell biology",
                "2009 Jul 27",
                "Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S",
                "protein_xref_pubmed",
                "19620632",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "NAADP mobilizes calcium from acidic organelles through two-pore channels.",
                "Nature",
                "2009 May 28",
                "Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX",
                "protein_xref_pubmed",
                "19387438",
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                "Q8NHX9"
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            [
                "Q8NHX9-1",
                "mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.",
                "Cell",
                "2013-02-14",
                "Cang Chunlei, Zhou Yandong, Navarro Betsy, Seo Young-Jun, Aranda Kimberly, Shi Lucy, Battaglia-Hsu Shyuefang, Nissim Itzhak, Clapham David E, Ren Dejian",
                "protein_xref_pubmed",
                "23394946",
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                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "Structural mechanisms of phospholipid activation of the human TPC2 channel.",
                "eLife",
                "2019 Mar 12",
                "She J, Zeng W, Guo J, Chen Q, Bai XC, Jiang Y",
                "protein_xref_pubmed",
                "30860481",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.",
                "eLife",
                "2020 Mar 16",
                "Gerndt S, Chen CC, Chao YK, Yuan Y, Burgstaller S, Scotto Rosato A, Krogsaeter E, Urban N, Jacob K, Nguyen ONP, Miller MT, Keller M, Vollmar AM, Gudermann T, Zierler S, Schredelseker J, Schaefer M, Biel M, Malli R, Wahl-Schott C, Bracher F, Patel S, Grimm C",
                "protein_xref_pubmed",
                "32167471",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "Convergent regulation of the lysosomal two-pore channel-2 by Mg(2)(+), NAADP, PI(3,5)P(2) and multiple protein kinases.",
                "The EMBO journal",
                "2014 Mar 3",
                "Jha A, Ahuja M, Patel S, Brailoiu E, Muallem S",
                "protein_xref_pubmed",
                "24502975",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
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                "Q8NHX9-1",
                "TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes.",
                "Cell",
                "2012 Oct 12",
                "Wang X, Zhang X, Dong XP, Samie M, Li X, Cheng X, Goschka A, Shen D, Zhou Y, Harlow J, Zhu MX, Clapham DE, Ren D, Xu H",
                "protein_xref_pubmed",
                "23063126",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals.",
                "The Journal of biological chemistry",
                "2010 Dec 3",
                "Brailoiu E, Rahman T, Churamani D, Prole DL, Brailoiu GC, Hooper R, Taylor CW, Patel S",
                "protein_xref_pubmed",
                "20880839",
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                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "The voltage-gated sodium channel TPC1 confers endolysosomal excitability.",
                "Nature chemical biology",
                "2014 Jun",
                "Cang C, Bekele B, Ren D",
                "protein_xref_pubmed",
                "24776928",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "Agonist-specific voltage-dependent gating of lysosomal two-pore Na+ channels.",
                "eLife",
                "2019-12-11",
                "Zhang Xiaoli, Chen Wei, Li Ping, Calvo Raul, Southall Noel, Hu Xin, Bryant-Genevier Melanie, Feng Xinghua, Geng Qi, Gao Chenlang, Yang Meimei, Tang Kaiyuan, Ferrer Marc, Marugan Juan Jose, Xu Haoxing",
                "protein_xref_pubmed",
                "31825310",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "TPC2 controls pigmentation by regulating melanosome pH and size.",
                "Proceedings of the National Academy of Sciences of the United States of America",
                "2016-05-17",
                "Ambrosio Andrea L, Boyle Judith A, Aradi Al E, Christian Keith A, Di Pietro Santiago M",
                "protein_xref_pubmed",
                "27140606",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q8NHX9-1",
                "Targeting Two-Pore Channels: Current Progress and Future Challenges.",
                "Trends in pharmacological sciences",
                "2020-08",
                "Jin Xuhui, Zhang Yuxuan, Alharbi Abeer, Hanbashi Ali, Alhoshani Ali, Parrington John",
                "protein_xref_pubmed",
                "32679067",
                "protein_xref_uniprotkb",
                "Q8NHX9"
            ],
            [
                "Q9NXR8-1",
                "A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis.",
                "Oncogene",
                "2003 Jan 23",
                "Nagashima M, Shiseki M, Pedeux RM, Okamura S, Kitahama-Shiseki M, Miura K, Yokota J, Harris CC",
                "protein_xref_pubmed",
                "12545155",
                "protein_xref_uniprotkb",
                "Q9NXR8"
            ],
            [
                "Q9NXR8-1",
                "ANP32E is a histone chaperone that removes H2A.Z from chromatin.",
                "Nature",
                "2014 Jan 30",
                "Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C, Hamiche A",
                "protein_xref_pubmed",
                "24463511",
                "protein_xref_uniprotkb",
                "Q9NXR8"
            ],
            [
                "Q9NXR8-1",
                "Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.",
                "Molecular and cellular biology",
                "2004-03",
                "Doyon Yannick, Selleck William, Lane William S, Tan Song, C\u00f4t\u00e9 Jacques",
                "protein_xref_pubmed",
                "14966270",
                "protein_xref_uniprotkb",
                "Q9NXR8"
            ],
            [
                "Q9C0H2-1",
                "A novel human Cl(-) channel family related to Drosophila flightless locus.",
                "The Journal of biological chemistry",
                "2004 May 21",
                "Suzuki M, Mizuno A",
                "protein_xref_pubmed",
                "15010458",
                "protein_xref_uniprotkb",
                "Q9C0H2"
            ],
            [
                "Q9C0H9-5",
                "p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.",
                "The EMBO journal",
                "2007 Jun 20",
                "Di Stefano P, Damiano L, Cabodi S, Aramu S, Tordella L, Praduroux A, Piva R, Cavallo F, Forni G, Silengo L, Tarone G, Turco E, Defilippi P",
                "protein_xref_pubmed",
                "17525734",
                "protein_xref_uniprotkb",
                "Q9C0H9"
            ],
            [
                "Q9C0H9-5",
                "Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.",
                "Neuron",
                "2009 Jan 15",
                "Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC",
                "protein_xref_pubmed",
                "19146815",
                "protein_xref_uniprotkb",
                "Q9C0H9"
            ],
            [
                "Q9C0H9-5",
                "P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.",
                "Molecular biology of the cell",
                "2004 Feb",
                "Di Stefano P, Cabodi S, Boeri Erba E, Margaria V, Bergatto E, Giuffrida MG, Silengo L, Tarone G, Turco E, Defilippi P",
                "protein_xref_pubmed",
                "14657239",
                "protein_xref_uniprotkb",
                "Q9C0H9"
            ],
            [
                "Q9NXR1-2",
                "Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.",
                "Current biology : CB",
                "2007 Jul 3",
                "Vergnolle MA, Taylor SS",
                "protein_xref_pubmed",
                "17600710",
                "protein_xref_uniprotkb",
                "Q9NXR1"
            ],
            [
                "Q9NXR1-2",
                "The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.",
                "American journal of human genetics",
                "2011 May 13",
                "Bakircioglu M, Carvalho OP, Khurshid M, Cox JJ, Tuysuz B, Barak T, Yilmaz S, Caglayan O, Dincer A, Nicholas AK, Quarrell O, Springell K, Karbani G, Malik S, Gannon C, Sheridan E, Crosier M, Lisgo SN, Lindsay S, Bilguvar K, Gergely F, Gunel M, Woods CG",
                "protein_xref_pubmed",
                "21529752",
                "protein_xref_uniprotkb",
                "Q9NXR1"
            ],
            [
                "Q9NXR7-2",
                "NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.",
                "Genes &amp; development",
                "2009 Mar 15",
                "Wang B, Hurov K, Hofmann K, Elledge SJ",
                "protein_xref_pubmed",
                "19261749",
                "protein_xref_uniprotkb",
                "Q9NXR7"
            ],
            [
                "Q9NXR7-2",
                "MERIT40 facilitates BRCA1 localization and DNA damage repair.",
                "Genes &amp; development",
                "2009 Mar 15",
                "Feng L, Huang J, Chen J",
                "protein_xref_pubmed",
                "19261748",
                "protein_xref_uniprotkb",
                "Q9NXR7"
            ],
            [
                "Q9NXR7-2",
                "The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells.",
                "The Journal of cell biology",
                "2015 Jul 20",
                "Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, Lin M, Zhang S, He Q, Zheng D, Tang J, Yin Y, Shao G",
                "protein_xref_pubmed",
                "26195665",
                "protein_xref_uniprotkb",
                "Q9NXR7"
            ],
            [
                "Q9NXR7-2",
                "A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses.",
                "Cell reports",
                "2013 Oct 17",
                "Zheng H, Gupta V, Patterson-Fortin J, Bhattacharya S, Katlinski K, Wu J, Varghese B, Carbone CJ, Aressy B, Fuchs SY, Greenberg RA",
                "protein_xref_pubmed",
                "24075985",
                "protein_xref_uniprotkb",
                "Q9NXR7"
            ],
            [
                "Q9NXR7-2",
                "A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.",
                "The Journal of biological chemistry",
                "2004-12-10",
                "Li Qing, Ching Arthur Kar-Keung, Chan Ben Chung-Lap, Chow Stephanie Ka-Yee, Lim Pak-Leong, Ho Tony Cheong-Yip, Ip Wai-Ki, Wong Chun-Kwok, Lam Christopher Wai-Kei, Lee Kenneth Ka-Ho, Chan John Yeuk-Hon, Chui Yiu-Loon",
                "protein_xref_pubmed",
                "15465831",
                "protein_xref_uniprotkb",
                "Q9NXR7"
            ],
            [
                "Q9NXR7-2",
                "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.",
                "Molecular cell",
                "2003 Nov",
                "Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R",
                "protein_xref_pubmed",
                "14636569",
                "protein_xref_uniprotkb",
                "Q9NXR7"
            ],
            [
                "Q96J66-1",
                "A functional ABCC11 allele is essential in the biochemical formation of human axillary odor.",
                "The Journal of investigative dermatology",
                "2010 Feb",
                "Martin A, Saathoff M, Kuhn F, Max H, Terstegen L, Natsch A",
                "protein_xref_pubmed",
                "19710689",
                "protein_xref_uniprotkb",
                "Q96J66"
            ],
            [
                "Q96J66-1",
                "A SNP in the ABCC11 gene is the determinant of human earwax type.",
                "Nature genetics",
                "2006 Mar",
                "Yoshiura K, Kinoshita A, Ishida T, Ninokata A, Ishikawa T, Kaname T, Bannai M, Tokunaga K, Sonoda S, Komaki R, Ihara M, Saenko VA, Alipov GK, Sekine I, Komatsu K, Takahashi H, Nakashima M, Sosonkina N, Mapendano CK, Ghadami M, Nomura M, Liang DS, Miwa N, Kim DK, Garidkhuu A, Natsume N, Ohta T, Tomita H, Kaneko A, Kikuchi M, Russomando G, Hirayama K, Ishibashi M, Takahashi A, Saitou N, Murray JC, Saito S, Nakamura Y, Niikawa N",
                "protein_xref_pubmed",
                "16444273",
                "protein_xref_uniprotkb",
                "Q96J66"
            ],
            [
                "Q96J66-1",
                "Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).",
                "Molecular pharmacology",
                "2005-02",
                "Chen Zhe-Sheng, Guo Yanping, Belinsky Martin G, Kotova Elena, Kruh Gary D",
                "protein_xref_pubmed",
                "15537867",
                "protein_xref_uniprotkb",
                "Q96J66"
            ],
            [
                "Q96J66-1",
                "Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant.",
                "The pharmacogenomics journal",
                "2016 Apr",
                "Arlanov R, Lang T, Jedlitschky G, Schaeffeler E, Ishikawa T, Schwab M, Nies AT",
                "protein_xref_pubmed",
                "25896536",
                "protein_xref_uniprotkb",
                "Q96J66"
            ],
            [
                "Q96J66-1",
                "Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?",
                "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
                "2009 Jun",
                "Toyoda Y, Sakurai A, Mitani Y, Nakashima M, Yoshiura K, Nakagawa H, Sakai Y, Ota I, Lezhava A, Hayashizaki Y, Niikawa N, Ishikawa T",
                "protein_xref_pubmed",
                "19383836",
                "protein_xref_uniprotkb",
                "Q96J66"
            ],
            [
                "Q96J66-1",
                "MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.",
                "The Journal of biological chemistry",
                "2003-08-08",
                "Guo Yanping, Kotova Elena, Chen Zhe-Sheng, Lee Kun, Hopper-Borge Elizabeth, Belinsky Martin G, Kruh Gary D",
                "protein_xref_pubmed",
                "12764137",
                "protein_xref_uniprotkb",
                "Q96J66"
            ],
            [
                "Q96J65-1",
                "Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm.",
                "The Biochemical journal",
                "2007 Aug 15",
                "Ono N, Van der Heijden I, Scheffer GL, Van de Wetering K, Van Deemter E, De Haas M, Boerke A, Gadella BM, De Rooij DG, Neefjes JJ, Groothuis TA, Oomen L, Brocks L, Ishikawa T, Borst P",
                "protein_xref_pubmed",
                "17472575",
                "protein_xref_uniprotkb",
                "Q96J65"
            ],
            [
                "Q9NQ75-1",
                "A novel Cas family member, HEPL, regulates FAK and cell spreading.",
                "Molecular biology of the cell",
                "2008 Apr",
                "Singh MK, Dadke D, Nicolas E, Serebriiskii IG, Apostolou S, Canutescu A, Egleston BL, Golemis EA",
                "protein_xref_pubmed",
                "18256281",
                "protein_xref_uniprotkb",
                "Q9NQ75"
            ],
            [
                "P40424-1",
                "Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene.",
                "Blood",
                "2003-06-15",
                "Okada Yoshiaki, Nagai Ryohei, Sato Takahiro, Matsuura Eri, Minami Takashi, Morita Ikuo, Doi Takefumi",
                "protein_xref_pubmed",
                "12609849",
                "protein_xref_uniprotkb",
                "P40424"
            ],
            [
                "P40424-1",
                "Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.",
                "Molecular and cellular biology",
                "1995-07",
                "Lu Q, Knoepfler P S, Scheele J, Wright D D, Kamps M P",
                "protein_xref_pubmed",
                "7791786",
                "protein_xref_uniprotkb",
                "P40424"
            ],
            [
                "P40424-1",
                "Cooperative transcriptional activation by Klf4, Meis2, and Pbx1.",
                "Molecular and cellular biology",
                "2011 Sep",
                "Bjerke GA, Hyman-Walsh C, Wotton D",
                "protein_xref_pubmed",
                "21746878",
                "protein_xref_uniprotkb",
                "P40424"
            ],
            [
                "P40424-1",
                "The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements.",
                "Oncogene",
                "1997-05-29",
                "Knoepfler P S, Kamps M P",
                "protein_xref_pubmed",
                "9191052",
                "protein_xref_uniprotkb",
                "P40424"
            ],
            [
                "P40424-1",
                "Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.",
                "Proceedings of the National Academy of Sciences of the United States of America",
                "1993-07-01",
                "Van Dijk M A, Voorhoeve P M, Murre C",
                "protein_xref_pubmed",
                "8327485",
                "protein_xref_uniprotkb",
                "P40424"
            ],
            [
                "P40425-1",
                "Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene.",
                "Blood",
                "2003-06-15",
                "Okada Yoshiaki, Nagai Ryohei, Sato Takahiro, Matsuura Eri, Minami Takashi, Morita Ikuo, Doi Takefumi",
                "protein_xref_pubmed",
                "12609849",
                "protein_xref_uniprotkb",
                "P40425"
            ],
            [
                "P40429-1",
                "Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation.",
                "RNA (New York, N.Y.)",
                "2007-12",
                "Chaudhuri Sujan, Vyas Keyur, Kapasi Purvi, Komar Anton A, Dinman Jonathan D, Barik Sailen, Mazumder Barsanjit",
                "protein_xref_pubmed",
                "17921318",
                "protein_xref_uniprotkb",
                "P40429"
            ],
            [
                "P40429-1",
                "L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational control.",
                "Molecular cell",
                "2007-01-12",
                "Kapasi Purvi, Chaudhuri Sujan, Vyas Keyur, Baus Diane, Komar Anton A, Fox Paul L, Merrick William C, Mazumder Barsanjit",
                "protein_xref_pubmed",
                "17218275",
                "protein_xref_uniprotkb",
                "P40429"
            ],
            [
                "P40429-1",
                "Structures of the human and Drosophila 80S ribosome.",
                "Nature",
                "2013 May 2",
                "Anger AM, Armache JP, Berninghausen O, Habeck M, Subklewe M, Wilson DN, Beckmann R",
                "protein_xref_pubmed",
                "23636399",
                "protein_xref_uniprotkb",
                "P40429"
            ],
            [
                "P40429-1",
                "Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.",
                "Nature communications",
                "2020-07-15",
                "Liang Xiaomeng, Zuo Mei-Qing, Zhang Yunyang, Li Ningning, Ma Chengying, Dong Meng-Qiu, Gao Ning",
                "protein_xref_pubmed",
                "32669547",
                "protein_xref_uniprotkb",
                "P40429"
            ],
            [
                "P40429-1",
                "Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control.",
                "Cell",
                "2003 Oct 17",
                "Mazumder B, Sampath P, Seshadri V, Maitra RK, DiCorleto PE, Fox PL",
                "protein_xref_pubmed",
                "14567916",
                "protein_xref_uniprotkb",
                "P40429"
            ],
            [
                "P40429-1",
                "Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.",
                "Molecular and cellular biology",
                "2012 Dec",
                "Arif A, Chatterjee P, Moodt RA, Fox PL",
                "protein_xref_pubmed",
                "23071094",
                "protein_xref_uniprotkb",
                "P40429"
            ],
            [
                "Q9H2I8-1",
                "Mutations in c10orf11, a melanocyte-differentiation gene, cause autosomal-recessive albinism.",
                "American journal of human genetics",
                "2013 Mar 7",
                "Gronskov K, Dooley CM, Ostergaard E, Kelsh RN, Hansen L, Levesque MP, Vilhelmsen K, Mollgard K, Stemple DL, Rosenberg T",
                "protein_xref_pubmed",
                "23395477",
                "protein_xref_uniprotkb",
                "Q9H2I8"
            ],
            [
                "P08842-1",
                "Novel point mutations in the steroid sulfatase gene in patients with X-linked ichthyosis: transfection analysis using the mutated genes.",
                "The Journal of investigative dermatology",
                "2000 Jun",
                "Oyama N, Satoh M, Iwatsuki K, Kaneko F",
                "protein_xref_pubmed",
                "10844566",
                "protein_xref_uniprotkb",
                "P08842"
            ],
            [
                "P08842-1",
                "Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein.",
                "The Journal of biological chemistry",
                "1997 Aug 15",
                "Alperin ES, Shapiro LJ",
                "protein_xref_pubmed",
                "9252398",
                "protein_xref_uniprotkb",
                "P08842"
            ],
            [
                "P08842-1",
                "Functional characterization of seven single-nucleotide polymorphisms of the steroid sulfatase gene found in a Japanese population.",
                "Journal of human genetics",
                "2013 May",
                "Matsumoto J, Ariyoshi N, Ishii I, Kitada M",
                "protein_xref_pubmed",
                "23466819",
                "protein_xref_uniprotkb",
                "P08842"
            ],
            [
                "P03891-1",
                "Mutated ND2 impairs mitochondrial complex I assembly and leads to Leigh syndrome.",
                "Molecular genetics and metabolism",
                "2007 Jan",
                "Ugalde C, Hinttala R, Timal S, Smeets R, Rodenburg RJ, Uusimaa J, van Heuvel LP, Nijtmans LG, Majamaa K, Smeitink JA",
                "protein_xref_pubmed",
                "16996290",
                "protein_xref_uniprotkb",
                "P03891"
            ],
            [
                "P03897-1",
                "Rapid identification of a novel complex I MT-ND3 m.10134C>A mutation in a Leigh syndrome patient.",
                "PloS one",
                "2014",
                "Miller DK, Menezes MJ, Simons C, Riley LG, Cooper ST, Grimmond SM, Thorburn DR, Christodoulou J, Taft RJ",
                "protein_xref_pubmed",
                "25118196",
                "protein_xref_uniprotkb",
                "P03897"
            ],
            [
                "P02760-1",
                "The cysteine 34 residue of A1M/alpha1-microglobulin is essential for protection of irradiated cell cultures and reduction of carbonyl groups.",
                "Free radical research",
                "2013 Jul",
                "Rutardottir S, Nilsson EJ, Pallon J, Gram M, Akerstrom B",
                "protein_xref_pubmed",
                "23642167",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Processing of the lipocalin alpha(1)-microglobulin by hemoglobin induces heme-binding and heme-degradation properties.",
                "Blood",
                "2002 Mar 15",
                "Allhorn M, Berggard T, Nordberg J, Olsson ML, Akerstrom B",
                "protein_xref_pubmed",
                "11877257",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Redox properties of the lipocalin alpha1-microglobulin: reduction of cytochrome c, hemoglobin, and free iron.",
                "Free radical biology & medicine",
                "2005 Mar 1",
                "Allhorn M, Klapyta A, Akerstrom B",
                "protein_xref_pubmed",
                "15683711",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "A1M/alpha1-microglobulin is proteolytically activated by myeloperoxidase, binds its heme group and inhibits low density lipoprotein oxidation.",
                "Frontiers in physiology",
                "2015",
                "Cederlund M, Deronic A, Pallon J, Sorensen OE, Akerstrom B",
                "protein_xref_pubmed",
                "25698971",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function.",
                "Antioxidants & redox signaling",
                "2013-06-01",
                "Olsson Magnus G, Rosenl\u00f6f Lena W, Kotarsky Heike, Olofsson Tor, Leanderson Tomas, M\u00f6rgelin Matthias, Fellman Vineta, \u00c5kerstr\u00f6m Bo",
                "protein_xref_pubmed",
                "23157686",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Up-regulation of A1M/\u03b11-microglobulin in skin by heme and reactive oxygen species gives protection from oxidative damage.",
                "PloS one",
                "2011",
                "Olsson Magnus G, Allhorn Maria, Larsson J\u00f6rgen, Cederlund Martin, Lundqvist Katarina, Schmidtchen Artur, S\u00f8rensen Ole E, M\u00f6rgelin Matthias, Akerstr\u00f6m Bo",
                "protein_xref_pubmed",
                "22096585",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "\u03b11-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro.",
                "International journal of molecular sciences",
                "2020-08-13",
                "Kristiansson Amanda, Davidsson Sara, Johansson Maria E, Piel Sarah, Elm\u00e9r Eskil, Hansson Magnus J, \u00c5kerstr\u00f6m Bo, Gram Magnus",
                "protein_xref_pubmed",
                "32823731",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Human radical scavenger alpha1-microglobulin protects against hemolysis in vitro and alpha1-microglobulin knockout mice exhibit a macrocytic anemia phenotype.",
                "Free radical biology & medicine",
                "2021 Jan",
                "Kristiansson A, Bergwik J, Alattar AG, Flygare J, Gram M, Hansson SR, Olsson ML, Storry JR, Allhorn M, Akerstrom B",
                "protein_xref_pubmed",
                "32092412",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by \u03b11-microglobulin.",
                "Placenta",
                "2011-04",
                "May K, Rosenl\u00f6f L, Olsson M G, Centlow M, M\u00f6rgelin M, Larsson I, Cederlund M, Rutardottir S, Siegmund W, Schneider H, Akerstr\u00f6m B, Hansson S R",
                "protein_xref_pubmed",
                "21356557",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.",
                "The Journal of biological chemistry",
                "2014 Nov 21",
                "Pendlebury D, Wang R, Henin RD, Hockla A, Soares AS, Madden BJ, Kazanov MD, Radisky ES",
                "protein_xref_pubmed",
                "25301953",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release.",
                "American journal of respiratory cell and molecular biology",
                "2007-01",
                "Forteza Rosanna, Casalino-Matsuda Susana M, Monzon Maria Elena, Fries Erik, Rugg Marilyn S, Milner Caroline M, Day Anthony J",
                "protein_xref_pubmed",
                "16873769",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments.",
                "The Journal of biological chemistry",
                "2005 Jul 22",
                "Mahoney DJ, Mulloy B, Forster MJ, Blundell CD, Fries E, Milner CM, Day AJ",
                "protein_xref_pubmed",
                "15917224",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Characterization of uronic-acid-rich inhibitor of calcium oxalate crystallization isolated from rat urine.",
                "Urological research",
                "1995",
                "Atmani F, Khan S R",
                "protein_xref_pubmed",
                "7676539",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "The TSG-6/HC2-mediated transfer is a dynamic process shuffling heavy chains between glycosaminoglycans.",
                "The Journal of biological chemistry",
                "2010-07-16",
                "Sanggaard Kristian W, Scavenius Carsten, Rasmussen Anna Julie, Wisniewski Hans-Georg, Th\u00f8gersen Ida B, Enghild Jan J",
                "protein_xref_pubmed",
                "20463016",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02760-1",
                "Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma.",
                "The Journal of biological chemistry",
                "1999-09-17",
                "Wilharm E, Parry M A, Friebel R, Tschesche H, Matschiner G, Sommerhoff C P, Jenne D E",
                "protein_xref_pubmed",
                "10480954",
                "protein_xref_uniprotkb",
                "P02760"
            ],
            [
                "P02766-1",
                "Transthyretin: a choroid plexus-specific transport protein in human brain. The 1986 S. Weir Mitchell award.",
                "Neurology",
                "1986 Jul",
                "Herbert J, Wilcox JN, Pham KT, Fremeau RT Jr, Zeviani M, Dwork A, Soprano DR, Makover A, Goodman DS, Zimmerman EA, et al.",
                "protein_xref_pubmed",
                "3714052",
                "protein_xref_uniprotkb",
                "P02766"
            ],
            [
                "P39023-1",
                "Structures of the human and Drosophila 80S ribosome.",
                "Nature",
                "2013 May 2",
                "Anger AM, Armache JP, Berninghausen O, Habeck M, Subklewe M, Wilson DN, Beckmann R",
                "protein_xref_pubmed",
                "23636399",
                "protein_xref_uniprotkb",
                "P39023"
            ],
            [
                "P39023-1",
                "Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.",
                "Nature communications",
                "2020-07-15",
                "Liang Xiaomeng, Zuo Mei-Qing, Zhang Yunyang, Li Ningning, Ma Chengying, Dong Meng-Qiu, Gao Ning",
                "protein_xref_pubmed",
                "32669547",
                "protein_xref_uniprotkb",
                "P39023"
            ],
            [
                "P39023-1",
                "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing.",
                "Journal of protein chemistry",
                "2003 Apr",
                "Odintsova TI, Muller EC, Ivanov AV, Egorov TA, Bienert R, Vladimirov SN, Kostka S, Otto A, Wittmann-Liebold B, Karpova GG",
                "protein_xref_pubmed",
                "12962325",
                "protein_xref_uniprotkb",
                "P39023"
            ],
            [
                "H0YL14-1",
                "Host cell protein C9orf69 promotes viral proliferation via interaction with HSV-1 UL25 protein.",
                "Virologica Sinica",
                "2011 Jun",
                "Zhang Y, Li YM, Liu LD, Jiang L, Ji M, Jiang RJ, Guo L, Liao Y, Li QH",
                "protein_xref_pubmed",
                "21667337",
                "protein_xref_uniprotkb",
                "H0YL14"
            ],
            [
                "Q9BXR3-1",
                "Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.",
                "Proceedings of the National Academy of Sciences of the United States of America",
                "2003-10-28",
                "Blaise Sandra, de Parseval Nathalie, B\u00e9nit Laurence, Heidmann Thierry",
                "protein_xref_pubmed",
                "14557543",
                "protein_xref_uniprotkb",
                "Q9BXR3"
            ],
            [
                "Q9BXR3-1",
                "An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein.",
                "Proceedings of the National Academy of Sciences of the United States of America",
                "1999 Nov 9",
                "Yang J, Bogerd HP, Peng S, Wiegand H, Truant R, Cullen BR",
                "protein_xref_pubmed",
                "10557333",
                "protein_xref_uniprotkb",
                "Q9BXR3"
            ]
        ]
    },
    "readme": "Name\n   - Human Protein Citations (UniProtKB)\n\nVersion\n   - v-2.4.1\n\nCreated on\n  - 2019-01-23T17:21:05.902655\n\nModified on\n   - 2022-09-26T08:48:18.842206\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Luke Johnson [luke.johnson@email.gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Cyrus Au-Yeung [cyruschauyeung@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n   - Maria Martin [martin@ebi.ac.uk], Preethi Vasudev [pvasudev@ebi.ac.uk]\n\nChecksum\n   - \n\nUsability Domain\n   - The Human Protein Citations dataset contains publication information for human [taxid:9606] UniProtKB accessions that includes PMID, journal name, date and author and title. Publications of large scale studies, and high frequency publications pertaining to genome sequencing, cDNA, chromosomes have been filtered out as per https://data.glygen.org/ln2data/releases/data/v-1.12.3/compiled/human_protein_blacklisted_pmids_uniprotkb.csv. The dataset is derived from 2019-09 UniProt release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen\n\nDescription Domain\n   Keywords\n   - publications\n   - PMID\n   - journal\n   - citations\n   - authors\n   - UniProtKB\n   - PubMed\n\n   Pipeline Steps\n   - Step-1: The script loads the UniProtKB publication data from the triplestore containing triples from nt file to retrieve the publication information associated with the UniProtKB accession and maps it to the UniProtKB canonical accessions. The script also filters out publications of large scale studies, and high frequency publications pertaining to DNA sequencing, cDNA, chromosomes using blacklisted PMIDs file.\n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: human_protein_blacklisted_pmids_uniprotkb.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/compiled/human_protein_blacklisted_pmids_uniprotkb.csv\n      Name: human_protein_function_uniprotkb.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/human_protein_function_uniprotkb.csv\n      Name: human_protein_ptm_annotation_uniprotkb.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/human_protein_ptm_annotation_uniprotkb.csv\n      Name: human_protein_site_annotation_uniprotkb.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/human_protein_site_annotation_uniprotkb.csv\n      Name: uniprot-proteome-homo-sapiens.nt\n      URI: https:/data.glygen.org/ln2downloads/ebi/2024_02_19/uniprot-proteome-homo-sapiens.nt\n   Output Subdomain\n      Name: human_protein_citations_uniprotkb.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/human_protein_citations_uniprotkb.csv\n      Name: human_protein_citations_uniprotkb.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.4.1/reviewed/human_protein_citations_uniprotkb.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\n     Description: \"\"\n      Unique Values: \"14602\"\n      Name: \"title\"\n     Description: \"Title of the published article in the journal\"\n      Unique Values: \"85202\"\n      Name: \"journal_name\"\n     Description: \"The name of the journal in which the article is published\"\n      Unique Values: \"2696\"\n      Name: \"publication_date\"\n     Description: \"Contains the full date on which the issue of the journal was published. Sourced from MEDLINE/PubMed data element(fields) description.\"\n      Unique Values: \"11052\"\n      Name: \"authors\"\n     Description: \"NA\"\n      Unique Values: \"84596\"\n      Name: \"xref_key\"\n     Description: \"Source key associated to the  xref_id\"\n      Unique Values: \"1\"\n      Name: \"xref_id\"\n     Description: \"ID of the X-ref\"\n      Unique Values: \"85232\"\n      Name: \"src_xref_key\"\n     Description: \"Source Xref  key\"\n      Unique Values: \"1\"\n      Name: \"src_xref_id\"\n     Description: \"Source X-ref ID\"\n      Unique Values: \"14820\"",
    "downloadurl": "/ln2data/releases/data/v-2.4.1/reviewed/human_protein_citations_uniprotkb.csv"
}
