{
    "disease_id": "DOID:0111989",
    "recommended_name": {
        "id": "DOID:0111989",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:0111989",
        "name": "immunodeficiency 35",
        "description": "A primary immunodeficiency disease characterized by increased susceptibility to mycobacterial infection after BCG vaccination and impaired cellular responses to IL-12, IFN-alpha/beta, IL-23, and IL-10 that has_material_basis_in homozygous or compound heterozygous mutation in the TYK2 gene on chromosome 19p13.2."
    },
    "synonyms": [
        {
            "id": "DOID:0111989",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111989",
            "name": "IMD35",
            "description": ""
        },
        {
            "id": "DOID:0111989",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111989",
            "name": "TYK2 deficiency",
            "description": ""
        },
        {
            "id": "DOID:0111989",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111989",
            "name": "susceptibility to infection due to TYK2 deficiency",
            "description": ""
        },
        {
            "id": "DOID:0111989",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111989",
            "name": "tyrosine kinase 2 deficiency",
            "description": ""
        },
        {
            "id": "DOID:0111989",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111989",
            "name": "autosomal recessiv HIES with atypical mycobacteriosis",
            "description": ""
        },
        {
            "id": "DOID:0111989",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111989",
            "name": "autosomal recessive hyper-IgE syndrome with atypical mycobacteriosis",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "immunodeficiency 35",
            "description": "Any hereditary predisposition to infections in which the cause of the disease is a mutation in the TYK2 gene."
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "HIES with atypical Mycobacteriosis, autosomal recessive",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "IMD35",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "TYK2 autosomal recessive mendelian susceptibility to mycobacterial diseases due to a partial deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "TYK2 deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "autosomal recessive hyper-IgE syndrome due to TYK2 deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "autosomal recessive mendelian susceptibility to mycobacterial diseases due to a partial deficiency caused by mutation in TYK2",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "hyper-IgE syndrome with atypical Mycobacteriosis, autosomal recessive",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "immunodeficiency 35",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "immunodeficiency type 35",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "susceptibility to infection due to TYK2 deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012682",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012682",
            "name": "tyrosine kinase 2 deficiency",
            "description": ""
        },
        {
            "id": "MIM:611521",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/611521",
            "name": "Immunodeficiency 35",
            "description": "Immunodeficiency 35"
        }
    ]
}