{
    "assessed_biomarker_entity": "Proteasome subunit beta type 9 (PSMB9)",
    "assessed_entity_type": "protein",
    "components": {
        "protein": [
            {
                "accession": "P28065-1",
                "name": "Proteasome subunit beta type-9",
                "evidence": [
                    {
                        "id": "GLY_000625",
                        "database": "GlyGen",
                        "url": "https://data.glygen.org/GLY_000625"
                    },
                    {
                        "id": "28482675",
                        "database": "PubMed",
                        "url": "https://glygen.org/publication/PubMed/28482675"
                    }
                ]
            }
        ],
        "glycan": []
    },
    "instances": [
        {
            "best_biomarker_type": "diagnostic",
            "status": "decreased PSMB9 level",
            "notes": "Uterine leiomyosarcoma tissue (UN:0000459)|Loss in expression of PSMB9/Beta1i",
            "literature_evidence": "The immunohistochemistry (IHC) experiments, performed separately at several medical facilities, revealed a serious loss in the ability to induce PSMB9/beta1i expression in human uterine LMS tissues in comparison with normal human myometrium tissues located in same tissue sections. [PMID:28482675]",
            "loinc_code": "",
            "tissue": {
                "name": "uterus",
                "namespace": "UBERON",
                "id": "0000995",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000995"
            },
            "disease": {
                "disease_id": "DOID:363",
                "recommended_name": {
                    "id": "DOID:363",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:363",
                    "name": "uterine cancer",
                    "description": "A female reproductive organ cancer that is located_in the uterus."
                },
                "synonyms": [
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "CA - cancer of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "Tumour of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "malignant neoplasm of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "malignant uterine tumor",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "neoplasm of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "uterine tumor",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "uterus neoplasm",
                        "description": ""
                    }
                ]
            },
            "evidence": [
                {
                    "id": "GLY_000625",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                },
                {
                    "id": "28482675",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/28482675"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "A novel diagnostic biomarker for human uterine leiomyosarcoma: PSMB9/beta1i.",
            "journal": "Chinese clinical oncology",
            "authors": "Hayashi T, Kawano M, Sano K, Ichimura T, Gur G, Yaish P, Zharhary D, Kanai Y, Tonegawa S, Shiozawa T, Yaegashi N, Konishi I",
            "date": "2017",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "28482675",
                    "url": "https://glygen.org/publication/PubMed/28482675"
                }
            ],
            "evidence": [
                {
                    "id": "GLY_000625",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                }
            ]
        }
    ],
    "evidence": [
        {
            "id": "GLY_000625",
            "database": "GlyGen",
            "url": "https://data.glygen.org/GLY_000625"
        },
        {
            "id": "28482675",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/28482675"
        }
    ],
    "biomarker_id": "A0348",
    "aclist": [
        "P28065-1"
    ],
    "crossref": [],
    "section_stats": [
        {
            "table_id": "instances",
            "table_stats": [
                {
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                    "count": 1
                }
            ],
            "sort_fields": [
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                "tissue.id",
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        },
        {
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}