{
    "assessed_biomarker_entity": "Gamma-glutamyltransferase (GGT)",
    "assessed_entity_type": "protein",
    "components": {
        "protein": [
            {
                "accession": "P19440-1",
                "name": "Glutathione hydrolase 1 proenzyme",
                "evidence": [
                    {
                        "id": "GLY_000625",
                        "database": "GlyGen",
                        "url": "https://data.glygen.org/GLY_000625"
                    },
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                        "id": "27646551",
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                        "url": "https://glygen.org/publication/PubMed/27646551"
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        {
            "best_biomarker_type": "prognostic",
            "status": "increased GGT level",
            "notes": "",
            "literature_evidence": "Women with higher pre-treatment GGT serum levels showed impaired Overall Survival (OS) compared to women with normal low levels. Higher pre-treatment GGT serum levels were independently associated with unfavorable prognosis in women with ULMS. Thus, GGT seems to be a useful novel biomarker in ULMS. [PMID:27646551]",
            "loinc_code": "2324-2",
            "tissue": {
                "name": "blood",
                "namespace": "UBERON",
                "id": "0000178",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178"
            },
            "disease": {
                "disease_id": "DOID:363",
                "recommended_name": {
                    "id": "DOID:363",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:363",
                    "name": "uterine cancer",
                    "description": "A female reproductive organ cancer that is located_in the uterus."
                },
                "synonyms": [
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "CA - cancer of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "Tumour of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "malignant neoplasm of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "malignant uterine tumor",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "neoplasm of uterus",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "uterine tumor",
                        "description": ""
                    },
                    {
                        "id": "DOID:363",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:363",
                        "name": "uterus neoplasm",
                        "description": ""
                    }
                ]
            },
            "evidence": [
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                    "id": "GLY_000625",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                },
                {
                    "id": "27646551",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/27646551"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "Gamma-glutamyltransferase as novel biomarker in patients with uterine leiomyosarcoma.",
            "journal": "Scientific reports",
            "authors": "Schwameis R, Grimm C, Brodowicz T, Petru E, Hefler-Frischmuth K, Staudigl C, Reinthaller A, Heinze G, Polterauer S, Polterauer M",
            "date": "2016",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27646551",
                    "url": "https://glygen.org/publication/PubMed/27646551"
                }
            ],
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                    "url": "https://data.glygen.org/GLY_000625"
                }
            ]
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    ],
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        {
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        {
            "id": "27646551",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/27646551"
        }
    ],
    "biomarker_id": "A0347",
    "aclist": [
        "P19440-1"
    ],
    "crossref": [],
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