{
    "assessed_biomarker_entity": "DNA mismatch repair protein Mlh1 (MLH1)",
    "assessed_entity_type": "protein",
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                "accession": "P40692-1",
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            "notes": "EDRN biomarker|Low MLH1 expression",
            "literature_evidence": "Low MLH1 expression was associated with improved prognosis and is a possible predictor of the chemosensitivity of ovarian cancer. [PMID:31570444]",
            "loinc_code": "81691-8",
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                "namespace": "UBERON",
                "id": "0000992",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000992"
            },
            "disease": {
                "disease_id": "DOID:2394",
                "recommended_name": {
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                    "resource": "Disease Ontology",
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                    "name": "ovarian cancer",
                    "description": "A female reproductive organ cancer that is located_in the ovary."
                },
                "synonyms": [
                    {
                        "id": "DOID:2394",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:2394",
                        "name": "malignant Ovarian tumor",
                        "description": ""
                    },
                    {
                        "id": "DOID:2394",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:2394",
                        "name": "malignant tumour of ovary",
                        "description": ""
                    },
                    {
                        "id": "DOID:2394",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:2394",
                        "name": "ovarian neoplasm",
                        "description": ""
                    },
                    {
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                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:2394",
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                        "description": ""
                    },
                    {
                        "id": "DOID:2394",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:2394",
                        "name": "primary ovarian cancer",
                        "description": ""
                    },
                    {
                        "id": "DOID:2394",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:2394",
                        "name": "tumor of the Ovary",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0011931",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0011931",
                        "name": "ovarian cancer, susceptibility to, 1",
                        "description": ""
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                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0011931",
                        "name": "OVCAS1",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0011931",
                        "resource": "MONDO",
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                        "name": "ovarian cancer, susceptibility to",
                        "description": ""
                    },
                    {
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                        "name": "ovarian cancer, susceptibility to, 1",
                        "description": ""
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                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
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                        "name": "ovarian cancer",
                        "description": "A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas."
                    },
                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "ovarian neoplasm",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "ovary neoplasm",
                        "description": ""
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                    {
                        "id": "MONDO:0008170",
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                        "name": "tumor of the ovary",
                        "description": ""
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                    {
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                        "name": "tumour of the ovary",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "cancer of ovary",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "description": ""
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                    {
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                    {
                        "id": "MONDO:0008170",
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                    {
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                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "malignant ovarian tumour",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "malignant ovary neoplasm",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
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                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "malignant tumour of the ovary",
                        "description": ""
                    },
                    {
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                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "ovarian cancer, somatic",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
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                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "ovarian malignant tumor",
                        "description": ""
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                    {
                        "id": "MONDO:0008170",
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                        "description": ""
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                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "ovary cancer",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "ovarian cancer, epithelial",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0008170",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0008170",
                        "name": "primary ovarian cancer",
                        "description": ""
                    },
                    {
                        "id": "MIM:167000",
                        "resource": "MIM",
                        "url": "https://www.omim.org/entry/167000",
                        "name": "Ovarian cancer",
                        "description": "Ovarian cancer"
                    }
                ]
            },
            "evidence": [
                {
                    "id": "GLY_000625",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                },
                {
                    "id": "31570444",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/31570444"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "MLH1 Is a Prognostic Biomarker for Serous Ovarian Cancer Treated With Platinum- and Taxane-based Chemotherapy.",
            "journal": "Anticancer research",
            "authors": "Kawashima N, Yoshida H, Miwa M, Fujiwara K",
            "date": "2019",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "31570444",
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                }
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            "database": "PubMed",
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    ],
    "biomarker_id": "A0274",
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    ],
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