{
    "assessed_biomarker_entity": "Ground-glass opacity (GGO)",
    "assessed_entity_type": "image",
    "components": {
        "protein": [
            {
                "accession": "Q6P1J9-1",
                "name": "Parafibromin",
                "evidence": [
                    {
                        "id": "GLY_000625",
                        "database": "GlyGen",
                        "url": "https://data.glygen.org/GLY_000625"
                    },
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                        "id": "32161968",
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                        "url": "https://glygen.org/publication/PubMed/32161968"
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        ],
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    },
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        {
            "best_biomarker_type": "diagnostic",
            "status": "presence of",
            "notes": "Cartoid CTA scan|Apical ground-glass opacification",
            "literature_evidence": "The typical feature was multiple lobular ground-glass opacity  and subsegmental areas of consolidation in COVID-19 patients. CT scan may be a reliable test for screening COVID-19 cases. [PMID:32161968] We identified a simple, reliable, and accurate COVID-19 diagnostic and prognostic imaging biomarker obtained from CTA lung apices: the presence or absence of ground-glass opacification. [PMID: 32943416]",
            "loinc_code": "",
            "tissue": {
                "name": "lung",
                "namespace": "UBERON",
                "id": "0002048",
                "url": "http://purl.obolibrary.org/obo/UBERON_0002048"
            },
            "disease": {
                "disease_id": "DOID:0080600",
                "recommended_name": {
                    "id": "DOID:0080600",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080600",
                    "name": "COVID-19",
                    "description": "A Coronavirus infection that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2."
                },
                "synonyms": [
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "2019 Novel Coronavirus (2019-nCoV)",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "2019-nCoV infection",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "Wuhan coronavirus infection",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "Wuhan seafood market pneumonia virus infection",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "COVID19",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "SARS-CoV-2 infection",
                        "description": ""
                    }
                ]
            },
            "evidence": [
                {
                    "id": "GLY_000625",
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                    "url": "https://data.glygen.org/GLY_000625"
                },
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                    "id": "32161968",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32161968"
                },
                {
                    "id": "32943416",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32943416"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "A Comparative Study on the Clinical Features of Coronavirus 2019 (COVID-19) Pneumonia With Other Pneumonias.",
            "journal": "Clinical infectious diseases : an official publication of the Infectious Diseases Society of America",
            "authors": "Zhao D, Yao F, Wang L, Zheng L, Gao Y, Ye J, Guo F, Zhao H, Gao R",
            "date": "2020",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32161968",
                    "url": "https://glygen.org/publication/PubMed/32161968"
                }
            ],
            "evidence": [
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                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                }
            ]
        },
        {
            "title": "COVID-19 Stroke Apical Lung Examination Study: A Diagnostic and Prognostic Imaging Biomarker in Suspected Acute Stroke.",
            "journal": "AJNR. American journal of neuroradiology",
            "authors": "Siddiqui J, Bala F, Sciacca S, Falzon A M, Benger M, Matloob S A, Miller F N A C, Simister R J, Chatterjee I, Sztriha L K, Davagnanam I, Booth T C",
            "date": "2021-01",
            "reference": [
                {
                    "type": "PubMed",
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                }
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    ],
    "biomarker_id": "A0076",
    "aclist": [
        "Q6P1J9-1"
    ],
    "crossref": [],
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