{
    "uniprot_canonical_ac": "A0A8I5ZPL7-1",
    "uniprot_ac": "A0A8I5ZPL7",
    "uniprot_id": "A0A8I5ZPL7_RAT",
    "mass": {
        "chemical_mass": 55562.0,
        "monoisotopic_mass": 55562.0
    },
    "refseq": {
        "ac": "NP_001102505",
        "name": "protein spinster homolog 3",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102505"
    },
    "gene_names": [
        {
            "name": "Spns3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPL7",
            "id": "A0A8I5ZPL7"
        },
        {
            "name": "RGD1561884",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246848",
            "id": "XP_006246848"
        },
        {
            "name": "Spns3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246848",
            "id": "XP_006246848"
        }
    ],
    "protein_names": [
        {
            "name": "Sphingolipid transporter 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A8I5ZPL7"
        },
        {
            "name": "protein spinster homolog 3 isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246848",
            "id": "XP_006246848"
        },
        {
            "name": "protein spinster homolog 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102505",
            "id": "NP_001102505"
        },
        {
            "name": "spinster homolog 3; SPNS sphingolipid transporter 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102505",
            "id": "NP_001102505"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:14503",
            "recommended_name": {
                "id": "DOID:14503",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:14503",
                "name": "neuronal ceroid lipofuscinosis",
                "description": ""
            },
            "synonyms": [
                {
                    "id": "DOID:14503",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14503",
                    "name": "hereditary ceroid lipofuscinosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "neuronal ceroid lipofuscinosis 1",
                    "description": "A condition associated with mutation(s) in the PPT1 gene, encoding palmitoyl-protein thioesterase 1. The condition is one of a group of genetically heterogeneous neurodegenerative disorders, characterized by accumulation of intracellular lipopigments."
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "CLN1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "CLN1 disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "CLN1 variable age at onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "PPT1 neuronal ceroid lipofuscinosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "ceroid lipofuscinosis neuronal 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "ceroid lipofuscinosis, neuronal, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "ceroid lipofuscinosis, neuronal, 1, variable Age at onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "ceroid lipofuscinosis, neuronal, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "ceroid storage disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "neuronal ceroid lipofuscinosis 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "neuronal ceroid lipofuscinosis 1 variable age of onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "neuronal ceroid lipofuscinosis caused by mutation in PPT1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "neuronal ceroid lipofuscinosis type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "Santavuori disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "Santavuori-Haltia disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "adult CLN (type of CLN1)",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "classic late infantile CLN (type of CLN1)",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "infantile CLN (type of CLN1)",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "infantile neuronal ceroid lipofuscinosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "juvenile CLN (type of CLN1)",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "neuronal ceroid lipofuscinosis, infantile",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "congenital NCL",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "congenital neuronal ceroid lipofuscinosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009744",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009744",
                    "name": "lipofuscin storage disease",
                    "description": ""
                },
                {
                    "id": "MIM:256730",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/256730",
                    "name": "Ceroid lipofuscinosis, neuronal, 1",
                    "description": "Ceroid lipofuscinosis, neuronal, 1"
                }
            ],
            "evidence": [
                {
                    "id": "14503",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:14503"
                }
            ]
        },
        {
            "disease_id": "DOID:1927",
            "recommended_name": {
                "id": "DOID:1927",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1927",
                "name": "sphingolipidosis",
                "description": "A lipid storage disease characterized by functional deficiencies in the enzymes needed for lysosomal degradation of sphingolipid substrates."
            },
            "synonyms": [
                {
                    "id": "DOID:1927",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1927",
                    "name": "sphingolipidoses",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "1927",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1927"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5ZPL7",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5ZPL7"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Spns3",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPL7",
            "locus": {
                "chromosome": "10",
                "start_pos": 57114266,
                "end_pos": 57168951,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000015873",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000015873"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000015873",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000015873",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd17328",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17328",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "497946",
            "url": "https://www.ncbi.nlm.nih.gov/gene/497946",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR011701",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020846",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036259",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR044770",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR044770",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:497946",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:497946",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "HISDSHA",
            "url": "https://omabrowser.org/oma/group/HISDSHA/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4555119at2759",
            "url": "http://www.orthodb.org/?query=4555119at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23505",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23505",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23505:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23505:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07690",
            "url": "http://pfam.xfam.org/family/PF07690",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006246848",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006246848",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1561884",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1561884",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I5ZPL7",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPL7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZPL7-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZPL7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZCZ0",
            "url": "https://www.uniprot.org/uniprot/D3ZCZ0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZCZ0-1",
            "url": "https://www.uniprot.org/uniprot/D3ZCZ0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSRECIKPQTGGPQSQSLSPGGQYGALASGNCLPPSTSASWSLPRWRAYLAAAVLCYVNLLNYMNWFIIPGVLLDVQKYFHISDSHAGLLQTVFIGCLLVSAPVFGYLGDRYSRKAILSFGVLLWSGAGLSSSFISYQYSWLFFLSRGIVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRIMPCLDAVALALLILLVPDLPRGAAEKQGEVPVRAPRSSWYEDVRYLGRNWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEASRKYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPNSYLQHFLSLQHSFLCCAFAIVLGGGCFLLTALHLERDQARARQPGEETLDSKDIARRDTERQGLLSGTSTPTE",
        "length": 514,
        "header": "tr|A0A8I5ZPL7-1|A0A8I5ZPL7_RAT Isoform 1 of Sphingolipid transporter 3  OS=Rattus norvegicus OX=10116 GN=Spns3 PE=3 SV=1 CANONICAL=A0A8I5ZPL7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZPL7-1",
            "url": "",
            "sequence": {
                "sequence": "MSRECIKPQTGGPQSQSLSPGGQYGALASGNCLPPSTSASWSLPRWRAYLAAAVLCYVNLLNYMNWFIIPGVLLDVQKYFHISDSHAGLLQTVFIGCLLVSAPVFGYLGDRYSRKAILSFGVLLWSGAGLSSSFISYQYSWLFFLSRGIVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRIMPCLDAVALALLILLVPDLPRGAAEKQGEVPVRAPRSSWYEDVRYLGRNWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEASRKYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPNSYLQHFLSLQHSFLCCAFAIVLGGGCFLLTALHLERDQARARQPGEETLDSKDIARRDTERQGLLSGTSTPTE",
                "length": 514,
                "header": "tr|A0A8I5ZPL7-1|A0A8I5ZPL7_RAT Isoform 1 of Sphingolipid transporter 3  OS=Rattus norvegicus OX=10116 GN=Spns3 PE=3 SV=1 CANONICAL=A0A8I5ZPL7-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 57168669,
                "end_pos": 57114527,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000110777.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000110777.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000080396.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000080396.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZCZ0-1",
            "url": "",
            "sequence": {
                "sequence": "MSRECIKPQTGGPQSQSLSPGGQYGALASGNCLPPSTSASWSLPRWRAYLAAAVLCYVNLLNYMNWFIIPVFIGCLLVSAPVFGYLGDRYSRKAILSFGVLLWSGAGLSSSFISYQYSWLFFLSRGIVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRIMPCLDAVALALLILLVPDLPRGAAEKQGEVPVRAPRSSWYEDVRYLGRNWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEASRKYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPNSYLQHFLSLQHSFLCCAFAIVLGGGCFLLTALHLERDQARARQPGEETLDSKDIARRDTERQGLLSGTSTPTE",
                "length": 492,
                "header": "tr|D3ZCZ0-1|D3ZCZ0_RAT Computationally mapped isoform of Sphingolipid transporter 3  OS=Rattus norvegicus OX=10116 GN=Spns3 PE=3 SV=1 CANONICAL=A0A8I5ZPL7-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 57168669,
                "end_pos": 57114527,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000041886.3",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000041886.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000050332.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000050332.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:497946",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:497946",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6ZMD2-1",
            "protein_name": "Protein spinster homolog 3",
            "gene_name": "SPNS3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAGGMSAECPEPGPGGLQGQSPGPGRQCPPPITPTSWSLPPWRAYVAAAVLCYINLLNYMNWFIIAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFGILLWSGAGLSSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAVTMLTGNWRWALRVMPCLEAVALILLILLVPDPPRGAAETQGEGAVGGFRSSWCEDVRYLGKNWSFVWSTLGVTAMAFVTGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVIGVILGAEAARRYKKVIPGAEPLICASSLLATAPCLYLALVLAPTTLLASYVFLGLGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVGHILGDAGSPYLTGLISSVLRARRPDSYLQRFRSLQQSFLCCAFVIALGGGCFLLTALYLERDETRAWQPVTGTPDSNDVDSNDLERQGLLSGAGASTEEP",
                "length": 512
            },
            "evidence": [
                {
                    "id": "45229699",
                    "url": "http://www.informatics.jax.org/homology/45229699",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9D232-1",
            "protein_name": "Protein spinster homolog 3",
            "gene_name": "Spns3",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSTECLKPQTGGPQSQSLSQGGQYGALASGTCLPPSTPVPWSLPRWRAYLAAAVLCYINLLNYMNWFIIPGVLLDVQKYFHISDSHAGLLQTVFISCLLVSAPVFGYLGDRYNRKAILSFGILLWSGAGLSSSFISYQYSWLFFLSRGFVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRLMPCLDAMALALLILLVPDVPRGAAEKQGEVAVRAPRSSWCEDVRYLGRNWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEASRRYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPDSYLQHFLSLQHSFLCCAFAIVLGGGFFLLTALHLEKDQARARQPGKGTLDSKDIASRNTESQGLLSGTSTPTE",
                "length": 514
            },
            "evidence": [
                {
                    "id": "45229699",
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