{
    "uniprot_canonical_ac": "A0A8I5ZLP5-1",
    "uniprot_ac": "A0A8I5ZLP5",
    "uniprot_id": "A0A8I5ZLP5_RAT",
    "mass": {
        "chemical_mass": 68630.0,
        "monoisotopic_mass": 68630.0
    },
    "refseq": {
        "ac": "NP_001100562",
        "name": "IQ calmodulin-binding motif-containing protein 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100562"
    },
    "gene_names": [
        {
            "name": "Iqcb1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5",
            "id": "A0A8I5ZLP5"
        },
        {
            "name": "Iqcb1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248457",
            "id": "XP_006248457"
        },
        {
            "name": "NPHP5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248457",
            "id": "XP_006248457"
        }
    ],
    "protein_names": [
        {
            "name": "IQ calmodulin-binding motif containing 1; nephrocystin 5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100562",
            "id": "NP_001100562"
        },
        {
            "name": "IQ calmodulin-binding motif-containing protein 1 isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248457",
            "id": "XP_006248457"
        },
        {
            "name": "IQ calmodulin-binding motif-containing protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100562",
            "id": "NP_001100562"
        },
        {
            "name": "IQ motif containing B1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A8I5ZLP5"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050576",
            "recommended_name": {
                "id": "DOID:0050576",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050576",
                "name": "Senior-Loken syndrome",
                "description": "A syndrome characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease."
            },
            "synonyms": [
                {
                    "id": "DOID:0050576",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050576",
                    "name": "Loken Senior syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0050576",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050576",
                    "name": "renal-retinal syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "Senior-Loken syndrome 1",
                    "description": "Any Senior-Loken syndrome in which the cause of the disease is a mutation in the NPHP1 gene."
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "NPHP1 Senior-Loken syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "Senior-Loken syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "Senior-Loken syndrome caused by mutation in NPHP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "Senior-Loken syndrome type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "senior-loken syndrome-1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "Loken-Senior syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "SENIOR-Loken syndrome 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "SLSN1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "Senior-Loken syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "juvenile nephronophthisis with Leber amaurosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "renal dysplasia and retinal aplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009962",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009962",
                    "name": "renal-retinal syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "Senior-Loken syndrome 5",
                    "description": "Any Senior-Loken syndrome in which the cause of the disease is a mutation in the IQCB1 gene."
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "IQCB1 Senior-Loken syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "Senior-Loken syndrome 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "Senior-Loken syndrome caused by mutation in IQCB1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "Senior-Loken syndrome type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "SENIOR-Loken syndrome 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012225",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012225",
                    "name": "SLSN5",
                    "description": ""
                },
                {
                    "id": "MONDO:0011755",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011755",
                    "name": "senior-loken syndrome 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0011755",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011755",
                    "name": "SLSN3",
                    "description": ""
                },
                {
                    "id": "MONDO:0011755",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011755",
                    "name": "SENIOR-Loken syndrome 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "Senior-Loken syndrome 4",
                    "description": "Any Senior-Loken syndrome in which the cause of the disease is a mutation in the NPHP4 gene."
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "NPHP4 Senior-Loken syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "Senior-Loken syndrome 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "Senior-Loken syndrome caused by mutation in NPHP4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "Senior-Loken syndrome type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "SENIOR-Loken syndrome 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0011756",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011756",
                    "name": "SLSN4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "Senior-Loken syndrome 7",
                    "description": "Any Senior-Loken syndrome in which the cause of the disease is a mutation in the SDCCAG8 gene."
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "SDCCAG8 Senior-Loken syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "Senior-Loken syndrome 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "Senior-Loken syndrome caused by mutation in SDCCAG8",
                    "description": ""
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "Senior-Loken syndrome type 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "SENIOR-Loken syndrome 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0013326",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013326",
                    "name": "SLSN7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "Senior-Loken syndrome 6",
                    "description": "Any Senior-Loken syndrome in which the cause of the disease is a mutation in the CEP290 gene."
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "CEP290 Senior-Loken syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "Senior-Loken syndrome 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "Senior-Loken syndrome caused by mutation in CEP290",
                    "description": ""
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "Senior-Loken syndrome type 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "SENIOR-Loken syndrome 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012433",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012433",
                    "name": "SLSN6",
                    "description": ""
                },
                {
                    "id": "MIM:266900",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/266900",
                    "name": "Senior-Loken syndrome 1",
                    "description": "Senior-Loken syndrome 1"
                },
                {
                    "id": "MIM:609254",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/609254",
                    "name": "Senior-Loken syndrome 5",
                    "description": "Senior-Loken syndrome 5"
                },
                {
                    "id": "MIM:606996",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/606996",
                    "name": "Senior-Loken syndrome 4",
                    "description": "Senior-Loken syndrome 4"
                },
                {
                    "id": "MIM:613615",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613615",
                    "name": "Senior-Loken syndrome 7",
                    "description": "Senior-Loken syndrome 7"
                },
                {
                    "id": "MIM:610189",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/610189",
                    "name": "Senior-Loken syndrome 6",
                    "description": "Senior-Loken syndrome 6"
                }
            ],
            "evidence": [
                {
                    "id": "0050576",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050576"
                }
            ]
        },
        {
            "disease_id": "DOID:0110414",
            "recommended_name": {
                "id": "DOID:0110414",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110414",
                "name": "retinitis pigmentosa 3",
                "description": "A retinitis pigmentosa that has_material_basis_in mutation in the RPGR gene on chromosome Xp11."
            },
            "synonyms": [
                {
                    "id": "DOID:0110414",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110414",
                    "name": "RP3",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "retinitis pigmentosa 3",
                    "description": "Any retinitis pigmentosa in which the cause of the disease is a mutation in the RPGR gene."
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "RP3",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "RPGR retinitis pigmentosa",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "retinitis pigmentosa 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "retinitis pigmentosa caused by mutation in RPGR",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "retinitis pigmentosa type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "Choroidoretinal Degeneration with retinal reflex in heterozygous Women",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "cone-rod Degeneration, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010227",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010227",
                    "name": "retinitis pigmentosa 15",
                    "description": ""
                },
                {
                    "id": "MIM:300029",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/300029",
                    "name": "Retinitis pigmentosa 3",
                    "description": "Retinitis pigmentosa 3"
                }
            ],
            "evidence": [
                {
                    "id": "0110414",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110414"
                }
            ]
        },
        {
            "disease_id": "DOID:12712",
            "recommended_name": {
                "id": "DOID:12712",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:12712",
                "name": "nephronophthisis",
                "description": "A kidney disease that is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the second decade (juvenile form) or before the age of 5 years (infantile form) resulting from dysfunction of ciliary proteins (ciliopathy)."
            },
            "synonyms": [
                {
                    "id": "DOID:12712",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12712",
                    "name": "medullary cystic disease",
                    "description": ""
                },
                {
                    "id": "DOID:12712",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12712",
                    "name": "medullary cystic kidney",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "nephronophthisis 1",
                    "description": "Progressive tubulointerstitial nephritis inherited in an autosomal recessive manner. It is caused by mutations in the NPHP1 gene. Patients present with anemia, polyuria, and polydipsia during childhood. The progressive bilateral kidney damage results in renal failure."
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "NPH1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "NPHP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "NPHP1 nephronophthisis (disease)",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "familial juvenile nephronophthisis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "juvenile nephronophthisis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "juvenile nephronophthisis 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "nephronophthisis (disease) caused by mutation in NPHP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "nephronophthisis 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "nephronophthisis 1, juvenile",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "nephronophthisis type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "Nph1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009728",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009728",
                    "name": "nephronophthisis, familial juvenile",
                    "description": ""
                },
                {
                    "id": "MIM:256100",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/256100",
                    "name": "Nephronophthisis 1",
                    "description": "Nephronophthisis 1"
                }
            ],
            "evidence": [
                {
                    "id": "12712",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:12712"
                }
            ]
        },
        {
            "disease_id": "DOID:14791",
            "recommended_name": {
                "id": "DOID:14791",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:14791",
                "name": "Leber congenital amaurosis",
                "description": "A retinal disease that is characterized by nystagmus, sluggish or no pupillary responses, and severe vision loss or blindness."
            },
            "synonyms": [
                {
                    "id": "DOID:14791",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14791",
                    "name": "LCA",
                    "description": ""
                },
                {
                    "id": "DOID:14791",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14791",
                    "name": "Leber's amaurosis",
                    "description": ""
                },
                {
                    "id": "DOID:14791",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14791",
                    "name": "Leber's congenital amaurosis",
                    "description": ""
                },
                {
                    "id": "DOID:14791",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14791",
                    "name": "Leber's disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "Leber congenital amaurosis 1",
                    "description": "Any Leber congenital amaurosis in which the cause of the disease is a mutation in the GUCY2D gene."
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "GUCY2D Leber congenital amaurosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "LCA1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "Leber congenital amaurosis 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "Leber congenital amaurosis caused by mutation in GUCY2D",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "Leber congenital amaurosis type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "amaurosis congenita of Leber I",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "CRB",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "LCA",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "amaurosis congenita of Leber 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "amaurosis congenita of Leber, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008764",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008764",
                    "name": "retinal blindness, congenital",
                    "description": ""
                },
                {
                    "id": "MIM:204000",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/204000",
                    "name": "Leber congenital amaurosis 1",
                    "description": "Leber congenital amaurosis 1"
                }
            ],
            "evidence": [
                {
                    "id": "14791",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:14791"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5ZLP5",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Iqcb1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5",
            "locus": {
                "chromosome": "11",
                "start_pos": 63905590,
                "end_pos": 63960093,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000038868",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000038868"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000038868",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000038868",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "303915",
            "url": "https://www.ncbi.nlm.nih.gov/gene/303915",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000048",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027417",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028765",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028765",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:303915",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303915",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "IHGGWAT",
            "url": "https://omabrowser.org/oma/group/IHGGWAT/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3670690at2759",
            "url": "http://www.orthodb.org/?query=3670690at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15673",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15673",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR15673:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15673:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00612",
            "url": "http://pfam.xfam.org/family/PF00612",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5620912",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5620912",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006248457",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248457",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1310069",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310069",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I5ZLP5",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZLP5-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A6J0",
            "url": "https://www.uniprot.org/uniprot/D4A6J0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A6J0-1",
            "url": "https://www.uniprot.org/uniprot/D4A6J0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MKPAGTDPRILSLAAEVAKSPEQNVPVILLKLKEIINNTPLGSSELKKVKQDIYCYDLIQYCLLVLSQDSSRIQGGWSTISQLTQILSHCCVGLEPGEDGEEFYKELLPSAAENFLVLGRRLQTCFINATKGEEQDKLLHFFQIVTDSLFWLLGGHIQLIQNVLQSDHFLHLLQTDNVQIGATVMTLLQNILQINSGNLLKIEGKALHSILDEILFKLLSTPSPVIRSTATKLLLVLAESHQEILILLRLSACYKGLRSLLNKQETLTEFSRELRQLVDLLTPKIQQEVEEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRAKRTKMLLELNRQKEEEDLRLRLQLQKQRAMRLSRESRLSMLEIIHPGQVEKYNREIEEKSALTIQKHWRGYRERKNFRQQRPSLTEYKAAVTLQRAVLKFLAKCRKKKKLFASWHGLQELTDARRVELKQQVDDYVKRHPGSQMSDVASRELHAQAQERLQHYFMGRAIEERAQQHREALMAQISTNIEQLMKAPSLKEAEGKEPEQFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEEPGDEMDVPKDELSIDLGTLFIGGTKPP",
        "length": 598,
        "header": "tr|A0A8I5ZLP5-1|A0A8I5ZLP5_RAT Isoform 1 of IQ motif containing B1  OS=Rattus norvegicus OX=10116 GN=Iqcb1 PE=4 SV=1 CANONICAL=A0A8I5ZLP5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZLP5-1",
            "url": "",
            "sequence": {
                "sequence": "MKPAGTDPRILSLAAEVAKSPEQNVPVILLKLKEIINNTPLGSSELKKVKQDIYCYDLIQYCLLVLSQDSSRIQGGWSTISQLTQILSHCCVGLEPGEDGEEFYKELLPSAAENFLVLGRRLQTCFINATKGEEQDKLLHFFQIVTDSLFWLLGGHIQLIQNVLQSDHFLHLLQTDNVQIGATVMTLLQNILQINSGNLLKIEGKALHSILDEILFKLLSTPSPVIRSTATKLLLVLAESHQEILILLRLSACYKGLRSLLNKQETLTEFSRELRQLVDLLTPKIQQEVEEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRAKRTKMLLELNRQKEEEDLRLRLQLQKQRAMRLSRESRLSMLEIIHPGQVEKYNREIEEKSALTIQKHWRGYRERKNFRQQRPSLTEYKAAVTLQRAVLKFLAKCRKKKKLFASWHGLQELTDARRVELKQQVDDYVKRHPGSQMSDVASRELHAQAQERLQHYFMGRAIEERAQQHREALMAQISTNIEQLMKAPSLKEAEGKEPEQFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEEPGDEMDVPKDELSIDLGTLFIGGTKPP",
                "length": 598,
                "header": "tr|A0A8I5ZLP5-1|A0A8I5ZLP5_RAT Isoform 1 of IQ motif containing B1  OS=Rattus norvegicus OX=10116 GN=Iqcb1 PE=4 SV=1 CANONICAL=A0A8I5ZLP5-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 63957082,
                "end_pos": 63905929,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000100750.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000100750.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000078884.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000078884.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A6J0-1",
            "url": "",
            "sequence": {
                "sequence": "MKPAGTDPRILSLAAEVAKSPEQNVPVILLKLKEIINNTPLGSSELKKVKQDIYCYDLIQYCLLVLSQDSSRIQGGWSTISQLTQILSHCCVGLEPGEDGEEFYKELLPSAAENFLVLGRRLQTCFINATKGEEQDKLLHFFQIVTDSLFWLLGGHIQLIQNVLQSDHFLHLLQTDNVQIGATVMTLLQNILQINSGNLLKIEGKALHSILDEILFKLLSTPSPVIRSTATKLLLVLAESHQEILILLRLSACYKGLRSLLNKQETLTEFSRELRQLVDLLTPKIQQEVEEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRAKRTKMLLELNRQKEEEDLRLRLQLQKQRAMRLSRESRLSMLEIIHPGQVEKYNREIEEKSALTIQKHWRGYRERKNFRQQRPSLTEYKAAVTLQRAVLKFLAKCRKKKKLFASWHGLQELTDARRVELKQQVDDYVKRHPGSQMSDVASRELHAQAQERLQHYFMGRAIEERAQQHREALMAQISTNIEQLMSMLYICLCFINGITHARDVASKIFRSATNSLYSSP",
                "length": 557,
                "header": "tr|D4A6J0-1|D4A6J0_RAT Computationally mapped isoform of IQ motif containing B1  OS=Rattus norvegicus OX=10116 GN=Iqcb1 PE=4 SV=1 CANONICAL=A0A8I5ZLP5-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 63957082,
                "end_pos": 63906661,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000066616.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000066616.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000061216.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000061216.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:303915",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303915",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-5620912",
            "name": "Anchoring of the basal body to the plasma membrane",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5620912",
            "resource": "Reactome",
            "description": "Anchoring of the basal body to the plasma membrane"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q15051-1",
            "protein_name": "IQ calmodulin-binding motif-containing protein 1",
            "gene_name": "IQCB1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQYCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGRQLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQIGSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP",
                "length": 598
            },
            "evidence": [
                {
                    "id": "45231024",
                    "url": "http://www.informatics.jax.org/homology/45231024",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8BP00-1",
            "protein_name": "IQ calmodulin-binding motif-containing protein 1",
            "gene_name": "Iqcb1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MKPAGTDPRILSLAAEVAKSPEQNVPVILLKLKEIINNTPLGSSELKKVKQDIYCYDLIQYCLLVLSQDSSRIQGGWSTISQLTQILSHCCVGLEPGEDGEEFYKELLPSAAENFLILGRRLQTCFINATKGEEQDKLLHFFQIVTDSLFWLLGGHVQLIQNVLQSDHFLHLLQTDNVQIGASVMTLLQNILQINSGNLLKIEGKALHSILDEILFKLLSTPSPVIRSTATKLLLVLAESHQEILILLRLSACYKGLRSLLNKQETLTEFSRELRQLVDLLTPKIHQEVEEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRTKMMLELNRQKEEEDLRLKLQLQRQRAMRLSRESRLNMLEIIHPGQVEKYNREMEEKSALTIQKHWRGYRERKNFRQQRPSLTEYKAAVTLQRAVLKFLAKCRKKKKLFASWHGLQELTDARRVELKQQVDDYVKRHPCSQMSEAASRELHAQAQERLQHYFMGRAIEERAQQHREALMAQISTNIEQLMKAPSLKEAEGKEPEQFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEEPGDEVDVPKDELSIDLGMLFIGGTKPP",
                "length": 598
            },
            "evidence": [
                {
                    "id": "45231024",
                    "url": "http://www.informatics.jax.org/homology/45231024",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "maintenance of animal organ identity",
                        "id": "GO:0048496",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048496",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "photoreceptor cell maintenance",
                        "id": "GO:0045494",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cilium assembly",
                        "id": "GO:0060271",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "calmodulin binding",
                        "id": "GO:0005516",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "enzyme binding",
                        "id": "GO:0019899",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 7,
                "go_terms": [
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "centrosome",
                        "id": "GO:0005813",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cilium",
                        "id": "GO:0005929",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intercellular bridge",
                        "id": "GO:0045171",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "photoreceptor connecting cilium",
                        "id": "GO:0032391",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "photoreceptor outer segment",
                        "id": "GO:0001750",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5ZLP5",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5ZLP5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitotic spindle",
                        "id": "GO:0072686",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686",
                        "evidence": [
                            {
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