{
    "uniprot_canonical_ac": "A0A8I5Y075-1",
    "uniprot_ac": "A0A8I5Y075",
    "uniprot_id": "A0A8I5Y075_RAT",
    "mass": {
        "chemical_mass": 50141.0,
        "monoisotopic_mass": 50141.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Ift52",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y075",
            "id": "A0A8I5Y075"
        }
    ],
    "protein_names": [
        {
            "name": "Intraflagellar transport 52",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A8I5Y075"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050592",
            "recommended_name": {
                "id": "DOID:0050592",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050592",
                "name": "asphyxiating thoracic dystrophy",
                "description": "A bone development disease characterized by skeletal abnormalities and resulting in difficulty in breathing caused by mutations that result in ciliopathy."
            },
            "synonyms": [
                {
                    "id": "DOID:0050592",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050592",
                    "name": "short-rib thoracic dysplasia with or without polydactyly",
                    "description": ""
                },
                {
                    "id": "DOID:0050592",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050592",
                    "name": "Jeune syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0050592",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050592",
                    "name": "thoracic pelvic phalangeal dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "asphyxiating thoracic dystrophy 1",
                    "description": "An asphyxiating thoracic dystrophy associated with variation in the region 15q13."
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "ATD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "SRTD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "asphyxiating thoracic dystrophy 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "asphyxiating thoracic dystrophy type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "short-rib thoracic dysplasia 1 with or without polydactyly",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "Jeune syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008831",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008831",
                    "name": "thoracic-pelvic-phalangeal dystrophy",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0050592",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050592"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8I5Y075",
                    "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Ift52",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y075",
            "locus": {
                "chromosome": "3",
                "start_pos": 151696980,
                "end_pos": 151672493,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000007692",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000007692"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000007692",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000007692",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "IPR019196",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019196",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039975",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039975",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NWNVEQN",
            "url": "https://omabrowser.org/oma/group/NWNVEQN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12969",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12969",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12969:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12969:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09822",
            "url": "http://pfam.xfam.org/family/PF09822",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5610787",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5610787",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5620924",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5620924",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1311004",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311004",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K177",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K177",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K177-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K177-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5Y075",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y075",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5Y075-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y075-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A5T7",
            "url": "https://www.uniprot.org/uniprot/D4A5T7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A5T7-1",
            "url": "https://www.uniprot.org/uniprot/D4A5T7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MPLWRPLGQPCGNPEVTMEKELRSTILFNAYKKEVFTTNTGYKSLQKRLRSNWKIQSLKDEITSEKLIGVKLWITAGPREKFTAAEFEVLKKYLDSGGDILVMLGEGGESRFDTNINFLLEEYGIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREISRAAGKAVPGVIDEENSGNNAQALTFVYPYGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENSKIMDVVFQWLTTGDIHLNQIDAEDPEISDYTMVPDTATLSEQLRVCLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPLPALQPAVFPPSFRELPPPPLELFDLDETFSSEKARLAQITNKCTDEDLEFYVRKCGDILGVTSKLPKDQQDAKHILEHIFFQVVEFKKLNQEAH",
        "length": 443,
        "header": "tr|A0A8I5Y075-1|A0A8I5Y075_RAT Isoform 1 of Intraflagellar transport 52  OS=Rattus norvegicus OX=10116 GN=Ift52 PE=4 SV=1 CANONICAL=A0A8I5Y075-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K177-1",
            "url": "",
            "sequence": {
                "sequence": "MEKELRSTILFNAYKKEVFTTNTGYKSLQKRLRSNWKIQSLKDEITSEKLIGVKLWITAGPREKFTAAEFEVLKKYLDSGGDILVMLGEGGESRFDTNINFLLEEYGIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREISRAAGKAVPGVIDEENSGNNAQALTFVYPYGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENSKIMISDYTMVPDTATLSEQLRVCLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPLPALQPAVFPPSFRELPPPPLELFDLDETFSSEKARLAQITNKCTDEDLEFYVRKCGDILGVTSKLPKDQQDAKHILEHIFFQVVEFKKLNQEAH",
                "length": 403,
                "header": "tr|A0A0G2K177-1|A0A8I5Y075_RAT Computationally mapped isoform of Intraflagellar transport 52  OS=Rattus norvegicus OX=10116 GN=Ift52 PE=4 SV=2 CANONICAL=A0A8I5Y075-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 151696229,
                "end_pos": 151675835,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000078101.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000078101.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000071730.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000071730.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5Y075-1",
            "url": "",
            "sequence": {
                "sequence": "MPLWRPLGQPCGNPEVTMEKELRSTILFNAYKKEVFTTNTGYKSLQKRLRSNWKIQSLKDEITSEKLIGVKLWITAGPREKFTAAEFEVLKKYLDSGGDILVMLGEGGESRFDTNINFLLEEYGIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREISRAAGKAVPGVIDEENSGNNAQALTFVYPYGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENSKIMDVVFQWLTTGDIHLNQIDAEDPEISDYTMVPDTATLSEQLRVCLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPLPALQPAVFPPSFRELPPPPLELFDLDETFSSEKARLAQITNKCTDEDLEFYVRKCGDILGVTSKLPKDQQDAKHILEHIFFQVVEFKKLNQEAH",
                "length": 443,
                "header": "tr|A0A8I5Y075-1|A0A8I5Y075_RAT Isoform 1 of Intraflagellar transport 52  OS=Rattus norvegicus OX=10116 GN=Ift52 PE=4 SV=1 CANONICAL=A0A8I5Y075-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 151696229,
                "end_pos": 151672626,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000113137.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000113137.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000076599.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000076599.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A5T7-1",
            "url": "",
            "sequence": {
                "sequence": "MWMQTCNPNIWRQRQVTMEKELRSTILFNAYKKEVFTTNTGYKSLQKRLRSNWKIQSLKDEITSEKLIGVKLWITAGPREKFTAAEFEVLKKYLDSGGDILVMLGEGGESRFDTNINFLLEEYGIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREISRAAGKAVPGVIDEENSGNNAQALTFVYPYGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENSKIMDVVFQWLTTGDIHLNQIDAEDPEISDYTMVPDTATLSEQLRVCLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPLPALQPAVFPPSFRELPPPPLELFDLDETFSSEKARLAQITNKCTDEDLEFYVRKCGDILGVTSKLPKDQQDAKHILEHIFFQVVEFKKLNQEAH",
                "length": 443,
                "header": "tr|D4A5T7-1|D4A5T7_RAT Computationally mapped isoform of Intraflagellar transport 52  OS=Rattus norvegicus OX=10116 GN=Ift52 PE=4 SV=4 CANONICAL=A0A8I5Y075-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 151696229,
                "end_pos": 151675139,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000066260.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000066260.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000059169.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000059169.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-RNO-5610787",
            "name": "Hedgehog 'off' state",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5610787",
            "resource": "Reactome",
            "description": "Hedgehog 'off' state"
        },
        {
            "id": "R-RNO-5620924",
            "name": "Intraflagellar transport",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5620924",
            "resource": "Reactome",
            "description": "Intraflagellar transport"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 10,
                "go_terms": [
                    {
                        "name": "photoreceptor cell cilium",
                        "id": "GO:0097733",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097733",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "centrosome",
                        "id": "GO:0005813",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cilium",
                        "id": "GO:0005929",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "centriole",
                        "id": "GO:0005814",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ciliary basal body",
                        "id": "GO:0036064",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "photoreceptor connecting cilium",
                        "id": "GO:0032391",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ciliary base",
                        "id": "GO:0097546",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendrite terminus",
                        "id": "GO:0044292",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044292",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intraciliary transport particle B",
                        "id": "GO:0030992",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ciliary tip",
                        "id": "GO:0097542",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 13,
                "go_terms": [
                    {
                        "name": "cilium assembly",
                        "id": "GO:0060271",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of keratinocyte proliferation",
                        "id": "GO:0010839",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010839",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "determination of left/right symmetry",
                        "id": "GO:0007368",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heart looping",
                        "id": "GO:0001947",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dorsal/ventral pattern formation",
                        "id": "GO:0009953",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "embryonic digit morphogenesis",
                        "id": "GO:0042733",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "smoothened signaling pathway",
                        "id": "GO:0007224",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8I5Y075",
                                "url": "https://www.uniprot.org/uniprot/A0A8I5Y075"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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