{
    "uniprot_canonical_ac": "A0A804C8T0-1",
    "uniprot_ac": "A0A804C8T0",
    "uniprot_id": "HAPR2_MOUSE",
    "mass": {
        "chemical_mass": 30096.0,
        "monoisotopic_mass": 30096.0
    },
    "refseq": {
        "ac": "NP_001258477",
        "name": "HUWE1-associated protein modifying stress responses 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258477"
    },
    "gene_names": [
        {
            "name": "Hapstr2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A804C8T0",
            "id": "A0A804C8T0"
        },
        {
            "name": "Gm715",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258477",
            "id": "NP_001258477"
        },
        {
            "name": "Gm715",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A804C8T0",
            "id": "A0A804C8T0"
        },
        {
            "name": "Hapstr2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258477",
            "id": "NP_001258477"
        }
    ],
    "protein_names": [
        {
            "name": "HUWE1-associated protein modifying stress responses 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A804C8T0"
        },
        {
            "name": "HUWE1-associated protein modifying stress responses 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258477",
            "id": "NP_001258477"
        },
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            "name": "predicted pseudogene 715",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258477",
            "id": "NP_001258477"
        }
    ],
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        {
            "annotation": "Together with HAPSTR1 plays a central regulatory role in the cellular response to molecular stressors, such as DNA damage, nutrient scarcity, and protein misfolding. Regulates these multiple stress response signaling pathways by stabilizing HAPSTR1, but also independently of HAPSTR1.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A804C8T0",
                    "url": "https://www.uniprot.org/uniprot/A0A804C8T0#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A7P0TBJ1",
                    "url": "https://www.uniprot.org/uniprot/A0A7P0TBJ1#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
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                    "id": "A0A804C8T0",
                    "url": "https://www.uniprot.org/uniprot/A0A804C8T0"
                }
            ],
            "common_name": "Mouse"
        }
    ],
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        {
            "name": "Hapstr2",
            "url": "https://www.uniprot.org/uniprot/A0A804C8T0",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000082226",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000082226",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "279618",
            "url": "https://www.ncbi.nlm.nih.gov/gene/279618",
            "database": "GeneID",
            "categories": [
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            ]
        },
        {
            "id": "IPR029196",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029196",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR040308",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040308",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:279618",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:279618",
            "database": "KEGG Pathway",
            "categories": [
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        },
        {
            "id": "2685561",
            "url": "http://www.informatics.jax.org/marker/MGI:2685561",
            "database": "MGI",
            "categories": [
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        },
        {
            "id": "PGLSMWD",
            "url": "https://omabrowser.org/oma/group/PGLSMWD/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR31624",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31624",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR31624:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31624:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF15251",
            "url": "http://pfam.xfam.org/family/PF15251",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001258477",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258477",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
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            "id": "A0A804C8T0",
            "url": "https://www.uniprot.org/uniprot/A0A804C8T0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A804C8T0-1",
            "url": "https://www.uniprot.org/uniprot/A0A804C8T0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MEDQPKDREAEVAGPWFSKWERQCLAEAEQAEQLSPELQEEAAADAAGLKIERQRLWHLFQISATAVAQLYKDSGCQQPGLSMWDPFQNAAMAVTSLYKESGDAYQRSFELGVQVGYQRRVRDVLEWVKKGRSIIRREDLISFLCGKVPPTPQPPRTPRMSPRPPAAASTQAAATESGTPVGVDLQPFHEAIALHGLSGAMASISMRSGPPGSSSQDGGIASSGRWKSSFLENDPNSLSSEELTLLLDSGGVRKRTSAQFGDGSADSPLHKRNRMV",
        "length": 276,
        "header": "sp|A0A804C8T0-1|HAPR2_MOUSE Isoform 1 of HUWE1-associated protein modifying stress responses 2  OS=Mus musculus OX=10090 GN=Hapstr2 PE=3 SV=1 CANONICAL=A0A804C8T0-1"
    },
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        {
            "isoform_ac": "A0A804C8T0-1",
            "url": "",
            "sequence": {
                "sequence": "MEDQPKDREAEVAGPWFSKWERQCLAEAEQAEQLSPELQEEAAADAAGLKIERQRLWHLFQISATAVAQLYKDSGCQQPGLSMWDPFQNAAMAVTSLYKESGDAYQRSFELGVQVGYQRRVRDVLEWVKKGRSIIRREDLISFLCGKVPPTPQPPRTPRMSPRPPAAASTQAAATESGTPVGVDLQPFHEAIALHGLSGAMASISMRSGPPGSSSQDGGIASSGRWKSSFLENDPNSLSSEELTLLLDSGGVRKRTSAQFGDGSADSPLHKRNRMV",
                "length": 276,
                "header": "sp|A0A804C8T0-1|HAPR2_MOUSE Isoform 1 of HUWE1-associated protein modifying stress responses 2  OS=Mus musculus OX=10090 GN=Hapstr2 PE=3 SV=1 CANONICAL=A0A804C8T0-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 59592452,
                "end_pos": 59591625,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000117865",
                        "url": "https://www.ensembl.org/id/ENSMUST00000117865"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00001091660",
                        "url": "https://www.ensembl.org/id/ENSMUSP00001091660"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:279618",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:279618",
            "resource": "KEGG Pathway"
        }
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    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
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                                "database": "UniProtKB",
                                "id": "A0A804C8T0",
                                "url": "https://www.uniprot.org/uniprot/A0A804C8T0"
                            }
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                        "pmid": ""
                    }
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            {
                "name": "Molecular Function",
                "total": 1,
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                    {
                        "name": "ubiquitin protein ligase binding",
                        "id": "GO:0031625",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625",
                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "A0A804C8T0",
                                "url": "https://www.uniprot.org/uniprot/A0A804C8T0"
                            }
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                        "pmid": ""
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            {
                "name": "Biological Process",
                "total": 1,
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                    {
                        "name": "protein stabilization",
                        "id": "GO:0050821",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821",
                        "evidence": [
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                                "id": "A0A804C8T0",
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                            }
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                        "pmid": ""
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    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
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    "cluster_types": [],
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