{ "uniprot_canonical_ac": "A0A571BEE2-1", "uniprot_ac": "A0A571BEE2", "uniprot_id": "A0A571BEE2_MOUSE", "mass": { "chemical_mass": 70628.0, "monoisotopic_mass": 70628.0 }, "refseq": { "ac": "XP_017175914", "name": "cylicin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017175914" }, "gene_names": [ { "name": "Cylc2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A571BEE2", "id": "A0A571BEE2" }, { "name": "4930488P18Rik", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017175914", "id": "XP_017175914" }, { "name": "Cylc2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017175914", "id": "XP_017175914" } ], "protein_names": [ { "name": "Cylicin, basic protein of sperm head cytoskeleton 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A571BEE2" }, { "name": "cylicin-2 isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017175914", "id": "XP_017175914" }, { "name": "cylicin-2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156337", "id": "NP_001156337" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A571BEE2", "url": "https://www.uniprot.org/uniprot/A0A571BEE2" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Cylc2", "url": "https://www.uniprot.org/uniprot/A0A571BEE2", "locus": { "chromosome": "4", "start_pos": 51250622, "end_pos": 51216678, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000039555", "url": "https://www.ensembl.org/id/ENSMUSG00000039555" } ] } } ], "crossref": [ { "id": "ENSMUSG00000039555", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000039555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "74914", "url": "https://www.ncbi.nlm.nih.gov/gene/74914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:74914", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1922164", "url": "http://www.informatics.jax.org/marker/MGI:1922164", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "CVESFDE", "url": "https://omabrowser.org/oma/group/CVESFDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4607493at2759", "url": "http://www.orthodb.org/?query=4607493at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16742:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16742:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15241", "url": "http://pfam.xfam.org/family/PF15241", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_017175914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017175914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A571BEE2", "url": "https://www.uniprot.org/uniprot/A0A571BEE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A571BEE2-1", "url": "https://www.uniprot.org/uniprot/A0A571BEE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B1AWN8", "url": "https://www.uniprot.org/uniprot/B1AWN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B1AWN8-1", "url": "https://www.uniprot.org/uniprot/B1AWN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIPRFLKVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNTAPVIDEEKLGVHRPPLWMHRSLMRISERPSVYLAARKGLIPKPLHFGKGESKSVGTHKSLASEKTKKEVKMKKDGFEAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATESGGEKAGSKKEAKDDKKDATSSQETLLSTAADKDGKKKEEKPVKQSSKSKDTVKDSASEKGDEKKEDKKEGKKEKKKKDGEGKEGGKKEKKDKKDKKDKKDKKDKKDKKDKKEKDKKDKKDKKDKKDKKDKKDKKDKKDKKAK", "length": 665, "header": "tr|A0A571BEE2-1|A0A571BEE2_MOUSE Isoform 1 of Cylicin, basic protein of sperm head cytoskeleton 2 OS=Mus musculus OX=10090 GN=Cylc2 PE=1 SV=1 CANONICAL=A0A571BEE2-1" }, "isoforms": [ { "isoform_ac": "A0A571BEE2-1", "url": "", "sequence": { "sequence": "MSIPRFLKVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNTAPVIDEEKLGVHRPPLWMHRSLMRISERPSVYLAARKGLIPKPLHFGKGESKSVGTHKSLASEKTKKEVKMKKDGFEAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATESGGEKAGSKKEAKDDKKDATSSQETLLSTAADKDGKKKEEKPVKQSSKSKDTVKDSASEKGDEKKEDKKEGKKEKKKKDGEGKEGGKKEKKDKKDKKDKKDKKDKKDKKDKKEKDKKDKKDKKDKKDKKDKKDKKDKKDKKAK", "length": 665, "header": "tr|A0A571BEE2-1|A0A571BEE2_MOUSE Isoform 1 of Cylicin, basic protein of sperm head cytoskeleton 2 OS=Mus musculus OX=10090 GN=Cylc2 PE=1 SV=1 CANONICAL=A0A571BEE2-1" }, "locus": { "chromosome": "4", "start_pos": 51229925, "end_pos": 51216706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000156384.4", "url": "https://www.ensembl.org/id/ENSMUST00000156384.4" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000158665.2", "url": "https://www.ensembl.org/id/ENSMUSP00000158665.2" } ] } }, { "isoform_ac": "B1AWN8-1", "url": "", "sequence": { "sequence": "MSIPRFLKVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNTAPVIDEEKLGVHRPPLWMHRSLMRISERPSVYLAARKGLIPKPLHFGKGESKSVGTHKSLASEKTKKEVKMKKDGFEAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATESGGEKAGSKKEAKDDKKDATSSQETLLSTAADKDGKKKEEKPVKQSSKSKDTVKDSASEKGDEKKEDKKEGKKEKKKKDGEGKEGGKKEKKDKKDKKDKKDKKDKKDKKDKKEKDKKDKKDKKDKKDKKDKKDKKDKKDKKAK", "length": 422, "header": "tr|B1AWN8-1|A0A571BEE2_MOUSE Computationally mapped isoform of Cylicin, basic protein of sperm head cytoskeleton 2 OS=Mus musculus OX=10090 GN=Cylc2 PE=1 SV=2 CANONICAL=A0A571BEE2-1" }, "locus": { "chromosome": "4", "start_pos": 51229925, "end_pos": 51216706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000166749.2", "url": "https://www.ensembl.org/id/ENSMUST00000166749.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000125758.2", "url": "https://www.ensembl.org/id/ENSMUSP00000125758.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "mmu:74914", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74914", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ABA0-1", "protein_name": "Cylicin 2", "gene_name": "Cylc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIPRFLKVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNPAPVIDEQKLGIHKPPLWMHRSLMRISERPSVYLAARKSLPPKPPRFGKGEFKRAGTTKTLASEKSKKEVKLKKDECEAKEKKALKTEKEENLKPVDTKISKDSQKDKGKISSGSEGEKAGVKKDVTTSKKGTKGTDSASETGSDKPGVKKDIKTSKKGTKGTDSASESGNEKASGKKEAKTSKKGPKAKDSASETGSEKAGGKKEAKSSKKGLKAKESASDSGSEKAGGKKEAKSSKKGLKAKESASDSGSEKAGGKKGVKGSKKGLKAKESASDSGSEKAGGKKGVKGSKKGSKAKDSASETGSEKAGGKKDAKASKKVSKDKSSASESGGEKAGGKKEAKASKKVSKDKSSASESGGEKAGGKKEAKASKKVSKDKASPSESEVAKAGGKKEAKASKKVSKDKVSASESGGEKAGGKKEAKASKKVSKDKVSASESDGEKSGGKKEARASKKGSKDKASASESGGEKAGGKKEAKADKKSPKQSKETLVSKAVDKDVGKKEEKSVKQGSKGKDVVADSASEKGDAGKEAKKKEEKEKKKKGEGDAKEGSKKEKKDKKDKKDKKDKKDKKDKKDKKDKKEKKDKKEKKEKKAK", "length": 652 }, "evidence": [ { "id": "45240952", "url": "http://www.informatics.jax.org/homology/45240952", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14093-1", "protein_name": "Cylicin-2", "gene_name": "CYLC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLPRFQRVNFGPYDNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK", "length": 348 }, "evidence": [ { "id": "45240952", "url": "http://www.informatics.jax.org/homology/45240952", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A571BEE2", "url": "https://www.uniprot.org/uniprot/A0A571BEE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }