{ "uniprot_canonical_ac": "A0A499JF18-1", "uniprot_ac": "A0A499JF18", "uniprot_id": "A0A499JF18_DROME", "mass": { "chemical_mass": 133714.0, "monoisotopic_mass": 133714.0 }, "refseq": { "ac": "NP_727173", "name": "uncharacterized protein, isoform I", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_727173" }, "gene_names": [ { "name": "Cph", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "id": "A0A499JF18" }, { "name": "Bcl11; Dmel\\CG9650", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572385", "id": "NP_572385" }, { "name": "CG9650", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572385", "id": "NP_572385" }, { "name": "CG9650", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "id": "A0A499JF18" }, { "name": "Dmel\\CG9650", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "id": "A0A499JF18" }, { "name": "Dmel_CG9650", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "id": "A0A499JF18" } ], "protein_names": [ { "name": "CG9650-PG", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096899", "id": "NP_001096899" }, { "name": "CG9650-PI", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_727173", "id": "NP_727173" }, { "name": "CG9650-PJ", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572385", "id": "NP_572385" }, { "name": "CG9650-PL", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096900", "id": "NP_001096900" }, { "name": "Uncharacterized protein, isoform K", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A499JF18" }, { "name": "uncharacterized protein, isoform G", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096899", "id": "NP_001096899" }, { "name": "uncharacterized protein, isoform I", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_727173", "id": "NP_727173" }, { "name": "uncharacterized protein, isoform J", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572385", "id": "NP_572385" }, { "name": "uncharacterized protein, isoform L", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096900", "id": "NP_001096900" } ], "function": [], "disease": [ { "disease_id": "DOID:0060041", "recommended_name": { "id": "DOID:0060041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior." }, "synonyms": [], "evidence": [ { "id": "0060041", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ] }, { "disease_id": "DOID:0111979", "recommended_name": { "id": "DOID:0111979", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111979", "name": "immunodeficiency 49", "description": "A T cell deficiency characterized by T cell lymphopenia, low T-cell receptor excision circles, impaired T-cell proliferative responses, dysmorphic facial features, hypotonia and severe global developmental delay that has_material_basis_in heterozygous mutation in the BCL11B gene on chromosome 14q32.2." }, "synonyms": [ { "id": "DOID:0111979", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111979", "name": "IMD49", "description": "" }, { "id": "DOID:0111979", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111979", "name": "severe combined immunodeficiency, T-cell negative, B-cell positive, NK cell positive, with intellectual disability, spasticity, and craniofacial abnormalities", "description": "" }, { "id": "DOID:0111979", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111979", "name": "SCID, T-cell negative, B-cell positive, NK cell positive, with intellectual disability, spasticity, and craniofacial abnormalities", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "immunodeficiency 49", "description": "Any primary immunodeficiency disease in which the cause of the disease is a mutation in the BCL11B gene." }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "BCL11B primary immunodeficiency disease", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "IMD49", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "immunodeficiency 49", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "immunodeficiency 49; IMD49", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "immunodeficiency type 49", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "primary immunodeficiency disease caused by mutation in BCL11B", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "SCID, T cell-Negative, B cell-Positive, Nk cell-Positive, with intellectual disability, spasticity, and craniofacial abnormalities", "description": "" }, { "id": "MONDO:0014981", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014981", "name": "severe combined immunodeficiency, T cell-Negative, B cell-Positive, Nk cell-Positive, with intellectual disability, spasticity, and craniofacial abnormalities", "description": "" }, { "id": "MIM:617237", "resource": "MIM", "url": "https://www.omim.org/entry/617237", "name": "Immunodeficiency 49", "description": "Immunodeficiency 49" } ], "evidence": [ { "id": "0111979", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0111979" } ] }, { "disease_id": "DOID:10923", "recommended_name": { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "sickle cell anemia", "description": "A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape." }, "synonyms": [ { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "Hb SC disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "Hb-S/Hb-C disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "Hb-SS disease without crisis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "Hemoglobin S disease without crisis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "Sickle-cell/Hb-C disease without crisis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "drepanocytosis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "haemoglobin SC disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "hemoglobin SC disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10923", "name": "sickle cell anaemia", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "sickle cell anemia", "description": "Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur." }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Haemoglobin S disease without crisis", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Hb SC disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Hb-S/Hb-C disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Hb-SS disease without crisis", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Hemoglobin S disease without crisis", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "drepanocytosis", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "haemoglobin SC disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "hemoglobin SC disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "sickle cell anemia", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "sickle cell disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "sickle-cell/Hb-C disease without crisis", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "sickling disorder due to Haemoglobin S", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "sickling disorder due to Hemoglobin S", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Haemoglobin S disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "HbS disease", "description": "" }, { "id": "MONDO:0011382", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011382", "name": "Hemoglobin S disease", "description": "" }, { "id": "MIM:603903", "resource": "MIM", "url": "https://www.omim.org/entry/603903", "name": "Sickle cell disease", "description": "Sickle cell disease" } ], "evidence": [ { "id": "10923", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ] }, { "disease_id": "DOID:12241", "recommended_name": { "id": "DOID:12241", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:12241", "name": "beta thalassemia", "description": "A thalassemia characterized by the reduced or absent synthesis of the beta globin chains of hemoglobin." }, "synonyms": [ { "id": "MONDO:0013517", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013517", "name": "beta-thalassemia HBB/LCRB", "description": "Abnormal clinical manifestations of beta thalassemia that are as a result of the underlying genotype." }, { "id": "MONDO:0013517", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013517", "name": "thalassemia, beta", "description": "" }, { "id": "MONDO:0013517", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013517", "name": "thalassemia, hispanic gamma-delta-beta", "description": "" }, { "id": "MONDO:0013517", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013517", "name": "beta-thalassemia", "description": "" }, { "id": "MIM:613985", "resource": "MIM", "url": "https://www.omim.org/entry/613985", "name": "Beta-thalassemia", "description": "Beta-thalassemia" } ], "evidence": [ { "id": "12241", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:12241" } ] }, { "disease_id": "DOID:1289", "recommended_name": { "id": "DOID:1289", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." }, "synonyms": [ { "id": "DOID:1289", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1289", "name": "degenerative disease", "description": "" } ], "evidence": [ { "id": "1289", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "evidence": [ { "id": "3908", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:5419", "recommended_name": { "id": "DOID:5419", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." }, "synonyms": [ { "id": "DOID:5419", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5419", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizoaffective disorder", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia with or without an affective disorder", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia, susceptibility to", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "evidence": [ { "id": "5419", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "Niddm4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "noninsulin-dependent diabetes mellitus 4", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, non-insulin-dependent, susceptibility to", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, susceptibility to", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2, protection against", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2, susceptibility to", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II, susceptibility to", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "hypertension, insulin resistance-related, susceptibility to", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, susceptibility to", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "maturity-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus, susceptibility to", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "noninsulin-dependent diabetes mellitus 1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "noninsulin-dependent diabetes mellitus 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "noninsulin-dependent diabetes mellitus 3", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "evidence": [ { "id": "9352", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "common_name": "Fruit fly" } ], "gene": [ { "name": "Cph", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "locus": { "chromosome": "X", "start_pos": 7241932, "end_pos": 7137723, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029939", "url": "https://www.ensembl.org/id/FBgn0029939" } ] } } ], "crossref": [ { "id": "FBgn0029939", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029939", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029939", "url": "https://flybase.org/reports/FBgn0029939", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31660", "url": "https://www.ncbi.nlm.nih.gov/gene/31660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A8JV11", "url": "https://www.ebi.ac.uk/intact/interactors/id:A8JV11*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "A8JV12", "url": "https://www.ebi.ac.uk/intact/interactors/id:A8JV12*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9650", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG9650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TKCCEFC", "url": "https://omabrowser.org/oma/group/TKCCEFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5351439at2759", "url": "http://www.orthodb.org/?query=5351439at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "http://pfam.xfam.org/family/PF00096", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A023GPJ3", "url": "https://www.uniprot.org/uniprot/A0A023GPJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A023GPJ3-1", "url": "https://www.uniprot.org/uniprot/A0A023GPJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A499JF18-1", "url": "https://www.uniprot.org/uniprot/A0A499JF18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8JV11", "url": "https://www.uniprot.org/uniprot/A8JV11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8JV11-1", "url": "https://www.uniprot.org/uniprot/A8JV11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8JV12", "url": "https://www.uniprot.org/uniprot/A8JV12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8JV12-1", "url": "https://www.uniprot.org/uniprot/A8JV12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R9PY46", "url": "https://www.uniprot.org/uniprot/R9PY46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R9PY46-1", "url": "https://www.uniprot.org/uniprot/R9PY46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEAXLFSGFPVPLAPPPPLQQHQPHLQQPQQQQTSRSRIMSRIF", "length": 1254, "header": "tr|A0A499JF18-1|A0A499JF18_DROME Isoform 1 of Uncharacterized protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Cph PE=4 SV=1 CANONICAL=A0A499JF18-1" }, "isoforms": [ { "isoform_ac": "A0A023GPJ3-1", "url": "", "sequence": { "sequence": "MDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA", "length": 1140, "header": "tr|A0A023GPJ3-1|A0A499JF18_DROME Computationally mapped isoform of Uncharacterized protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Cph PE=4 SV=1 CANONICAL=A0A499JF18-1" }, "locus": { "chromosome": "X", "start_pos": 7239899, "end_pos": 7232528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0339815", "url": "https://www.ensembl.org/id/FBtr0339815" }, { "database": "Ensembl Peptide", "id": "FBpp0308848", "url": "https://www.ensembl.org/id/FBpp0308848" } ] } }, { "isoform_ac": "A0A499JF18-1", "url": "", "sequence": { "sequence": "MYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEAXLFSGFPVPLAPPPPLQQHQPHLQQPQQQQTSRSRIMSRIF", "length": 1254, "header": "tr|A0A499JF18-1|A0A499JF18_DROME Isoform 1 of Uncharacterized protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Cph PE=4 SV=1 CANONICAL=A0A499JF18-1" }, "locus": { "chromosome": "X", "start_pos": 7240022, "end_pos": 7226932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0474234", "url": "https://www.ensembl.org/id/FBtr0474234" }, { "database": "Ensembl Peptide", "id": "FBpp0423187", "url": "https://www.ensembl.org/id/FBpp0423187" } ] } }, { "isoform_ac": "A8JV11-1", "url": "", "sequence": { "sequence": "MYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA", "length": 1213, "header": "tr|A8JV11-1|A0A499JF18_DROME Computationally mapped isoform of Uncharacterized protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Cph PE=4 SV=3 CANONICAL=A0A499JF18-1" }, "locus": { "chromosome": "X", "start_pos": 7239899, "end_pos": 7226932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0474235", "url": "https://www.ensembl.org/id/FBtr0474235" }, { "database": "Ensembl Peptide", "id": "FBpp0423188", "url": "https://www.ensembl.org/id/FBpp0423188" } ] } }, { "isoform_ac": "A8JV12-1", "url": "", "sequence": { "sequence": "MFPGNMISPKVRGTNSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA", "length": 1209, "header": "tr|A8JV12-1|A0A499JF18_DROME Computationally mapped isoform of Uncharacterized protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Cph PE=4 SV=2 CANONICAL=A0A499JF18-1" }, "locus": { "chromosome": "X", "start_pos": 7239899, "end_pos": 7217846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0301240", "url": "https://www.ensembl.org/id/FBtr0301240" }, { "database": "Ensembl Peptide", "id": "FBpp0290458", "url": "https://www.ensembl.org/id/FBpp0290458" } ] } }, { "isoform_ac": "R9PY46-1", "url": "", "sequence": { "sequence": "MRIKMPAVRIAQDSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA", "length": 1207, "header": "tr|R9PY46-1|A0A499JF18_DROME Computationally mapped isoform of Uncharacterized protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Cph PE=4 SV=1 CANONICAL=A0A499JF18-1" }, "locus": { "chromosome": "X", "start_pos": 7239899, "end_pos": 7197309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0309030", "url": "https://www.ensembl.org/id/FBtr0309030" }, { "database": "Ensembl Peptide", "id": "FBpp0301059", "url": "https://www.ensembl.org/id/FBpp0301059" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dme:Dmel_CG9650", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG9650", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" }, { "name": "negative regulation of peptide hormone secretion", "id": "GO:0090278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090278", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" }, { "name": "neuroblast fate specification", "id": "GO:0014018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014018", "evidence": [ { "database": "UniProtKB", "id": "A0A499JF18", "url": "https://www.uniprot.org/uniprot/A0A499JF18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1027, "end_pos": 1029, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1042, "end_pos": 1044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1182, "end_pos": 1184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1196, "end_pos": 1198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }