{
    "uniprot_canonical_ac": "A0A2R8VHP3-1",
    "uniprot_ac": "A0A2R8VHP3",
    "uniprot_id": "A0A2R8VHP3_MOUSE",
    "mass": {
        "chemical_mass": 57920.0,
        "monoisotopic_mass": 57920.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Gm5478",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3",
            "id": "A0A2R8VHP3"
        },
        {
            "name": "Krt6a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3",
            "id": "A0A2R8VHP3"
        }
    ],
    "protein_names": [
        {
            "name": "Predicted pseudogene 5478",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A2R8VHP3"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050449",
            "recommended_name": {
                "id": "DOID:0050449",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050449",
                "name": "pachyonychia congenita",
                "description": "A syndrome that is characterized by hypertrophic nails and hyperkeratosis of the hands and feet and has_material_basis_in gene mutations that result in changes in keratin."
            },
            "synonyms": [
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "Jackson-Lawler Type Pachyonychia Congenita",
                    "description": ""
                },
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "Jadassohn-Lewandowsky Syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "PACHYONYCHIA CONGENITA, JADASSOHN-LEWANDOWSKY TYPE",
                    "description": ""
                },
                {
                    "id": "DOID:0050449",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050449",
                    "name": "Pachyonychia Congenita Type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita 1",
                    "description": "Any pachyonychia congenita in which the cause of the disease is a mutation in the KRT16 gene."
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "KRT16 pachyonychia congenita",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita caused by mutation in KRT16",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "Jadassohn-Lewandowsky syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "Jadassohn-Lewandowsky syndrome, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "PC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita, Jadassohn-Lewandowsky type",
                    "description": ""
                },
                {
                    "id": "MONDO:0008173",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008173",
                    "name": "pachyonychia congenita, Jadassohn-Lewandowsky type, formerly",
                    "description": ""
                },
                {
                    "id": "MIM:167200",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/167200",
                    "name": "Pachyonychia congenita 1",
                    "description": "Pachyonychia congenita 1"
                }
            ],
            "evidence": [
                {
                    "id": "0050449",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050449"
                }
            ]
        },
        {
            "disease_id": "DOID:0111710",
            "recommended_name": {
                "id": "DOID:0111710",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111710",
                "name": "focal or diffuse nonepidermolytic palmoplantar keratoderma",
                "description": "A nonepidermolytic palmoplantar keratoderma characterized by focal or diffuse palmoplantar keratodermas with minor or absent nail changes that has_material_basis_in heterozygous mutation in the KRT6C gene on chromosome 12q13.13."
            },
            "synonyms": [
                {
                    "id": "DOID:0111710",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111710",
                    "name": "PPKNEFD",
                    "description": ""
                },
                {
                    "id": "DOID:0111710",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111710",
                    "name": "autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "palmoplantar keratoderma, nonepidermolytic, focal or diffuse",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "palmoplantar keratoderma, nonepidermolytic, focal or diffuse",
                    "description": ""
                },
                {
                    "id": "MONDO:0014327",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014327",
                    "name": "PPKNEFD",
                    "description": ""
                },
                {
                    "id": "MIM:615735",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/615735",
                    "name": "Palmoplantar keratoderma, non-epidermolytic, focal or diffuse",
                    "description": "Palmoplantar keratoderma, non-epidermolytic, focal or diffuse"
                }
            ],
            "evidence": [
                {
                    "id": "0111710",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111710"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A2R8VHP3",
                    "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Gm5478",
            "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3",
            "locus": {
                "chromosome": "15",
                "start_pos": 101551455,
                "end_pos": 101555815,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000095241",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000095241"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000095241",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000095241",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "IPR003054",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032444",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039008",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3646318",
            "url": "http://www.informatics.jax.org/marker/MGI:3646318",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "PTHR45616",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45616:SF39",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF39",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00038",
            "url": "http://pfam.xfam.org/family/PF00038",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF16208",
            "url": "http://pfam.xfam.org/family/PF16208",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6805567",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6809371",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6809371",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A2R8VHP3",
            "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2R8VHP3-1",
            "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z6R0",
            "url": "https://www.uniprot.org/uniprot/D3Z6R0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z6R0-1",
            "url": "https://www.uniprot.org/uniprot/D3Z6R0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MCGGAGFGSRSLYGVGSSKRISIGGGSCGIGGGYGSRFGGAYGSRFGGSFGIGGGAGSGFGFGGGAGFGGGYGGAGFPVCPPGGIQEVTINQNLLTPLNVQIDPTIQWVRTEEREQIKTLNNKFASFIDKVQFLEQQNKVLDTKWALLQEQGTKNQRPDLETLFEQYISNLRRRLDSITGERGHLDSELRKMQDTAEDYKGKYEDEINKRTAAENEFVTVKKDVDAAYMTKVELQAKADSVADEINFLRVIFEAELSQVQTVVSDTTVVLSMDNNRSLDLDSIIAEVKAKYEDIVQRSRAEAETLYQTKYEELQVTAGRHGDNLRNTKQEIAEINRIIRRLKAEIDSVKKQLSKLQAEIDDAERRGEMALNDARGKMEGMEDALQKVKQDTARMLNEYQELMNAKLGLDVEIAAYRAILEGEEYRFSGEGAGPVNTSVKQQSTVSRAYGSTGGASSSLGPGRGSSHSYASVHGRYGFSAGSGRVIRGGLNSSVGNPSTISSNHQSLLWTPNSLAVMPCVQGHLLPASPPLLSAWV",
        "length": 535,
        "header": "tr|A0A2R8VHP3-1|A0A2R8VHP3_MOUSE Isoform 1 of Predicted pseudogene 5478  OS=Mus musculus OX=10090 GN=Gm5478 PE=1 SV=1 CANONICAL=A0A2R8VHP3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A2R8VHP3-1",
            "url": "",
            "sequence": {
                "sequence": "MCGGAGFGSRSLYGVGSSKRISIGGGSCGIGGGYGSRFGGAYGSRFGGSFGIGGGAGSGFGFGGGAGFGGGYGGAGFPVCPPGGIQEVTINQNLLTPLNVQIDPTIQWVRTEEREQIKTLNNKFASFIDKVQFLEQQNKVLDTKWALLQEQGTKNQRPDLETLFEQYISNLRRRLDSITGERGHLDSELRKMQDTAEDYKGKYEDEINKRTAAENEFVTVKKDVDAAYMTKVELQAKADSVADEINFLRVIFEAELSQVQTVVSDTTVVLSMDNNRSLDLDSIIAEVKAKYEDIVQRSRAEAETLYQTKYEELQVTAGRHGDNLRNTKQEIAEINRIIRRLKAEIDSVKKQLSKLQAEIDDAERRGEMALNDARGKMEGMEDALQKVKQDTARMLNEYQELMNAKLGLDVEIAAYRAILEGEEYRFSGEGAGPVNTSVKQQSTVSRAYGSTGGASSSLGPGRGSSHSYASVHGRYGFSAGSGRVIRGGLNSSVGNPSTISSNHQSLLWTPNSLAVMPCVQGHLLPASPPLLSAWV",
                "length": 535,
                "header": "tr|A0A2R8VHP3-1|A0A2R8VHP3_MOUSE Isoform 1 of Predicted pseudogene 5478  OS=Mus musculus OX=10090 GN=Gm5478 PE=1 SV=1 CANONICAL=A0A2R8VHP3-1"
            },
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                "chromosome": "15",
                "start_pos": 101555635,
                "end_pos": 101551828,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000229963.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000229963.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000155269.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000155269.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3Z6R0-1",
            "url": "",
            "sequence": {
                "sequence": "ELQVTAGRHGDNLRNTKQEIAEINRIIRRLKAEIDSVKKQLSKLQAEIDDAERRGEMALNDARGKMEGMEDALQKVKQDTARMLNEYQELMNAKLGLDVEIAAYRAILEGEEYRFSGEGAGPVNTSVKQQSTVSRAYGSTGGASSSLGPGRGSSHSYAS",
                "length": 159,
                "header": "tr|D3Z6R0-1|A0A2R8VHP3_MOUSE Computationally mapped isoform of Predicted pseudogene 5478  OS=Mus musculus OX=10090 GN=Gm5478 PE=1 SV=2 CANONICAL=A0A2R8VHP3-1"
            },
            "locus": {
                "chromosome": "15",
                "start_pos": 101553137,
                "end_pos": 101552023,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000100184.4",
                        "url": "https://www.ensembl.org/id/ENSMUST00000100184.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000097759.4",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000097759.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-MMU-6805567",
            "name": "Keratinization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "resource": "Reactome",
            "description": "Keratinization"
        },
        {
            "id": "R-MMU-6809371",
            "name": "Formation of the cornified envelope",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6809371",
            "resource": "Reactome",
            "description": "Formation of the cornified envelope"
        }
    ],
    "orthologs": [],
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        "categories": [
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
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                        "id": "GO:0031424",
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                                "id": "A0A2R8VHP3",
                                "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3"
                            }
                        ],
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                    },
                    {
                        "name": "intermediate filament organization",
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                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A2R8VHP3",
                                "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
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                "name": "Cellular Component",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095",
                        "evidence": [
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                                "database": "UniProtKB",
                                "id": "A0A2R8VHP3",
                                "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "structural constituent of skin epidermis",
                        "id": "GO:0030280",
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                                "database": "UniProtKB",
                                "id": "A0A2R8VHP3",
                                "url": "https://www.uniprot.org/uniprot/A0A2R8VHP3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
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            "annotation": "n_glycosylation_sequon"
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            "start_pos": 490,
            "end_pos": 492,
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    "ptm_annotation": [],
    "interactions": [],
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    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
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