{ "uniprot_canonical_ac": "A0A1D5RLD8-1", "uniprot_ac": "A0A1D5RLD8", "uniprot_id": "A0A1D5RLD8_MOUSE", "mass": { "chemical_mass": 35812.0, "monoisotopic_mass": 35812.0 }, "refseq": {}, "gene_names": [ { "name": "Gm10358", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8", "id": "A0A1D5RLD8" } ], "protein_names": [ { "name": "Glyceraldehyde-3-phosphate dehydrogenase", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A0A1D5RLD8" }, { "name": "1.2.1.12", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A1D5RLD8" } ], "function": [], "disease": [ { "disease_id": "DOID:0050827", "recommended_name": { "id": "DOID:0050827", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050827", "name": "rheumatic heart disease", "description": "A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords." }, "synonyms": [ { "id": "DOID:0050827", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050827", "name": "rheumatic carditis", "description": "" } ], "evidence": [ { "id": "0050827", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0050827" } ] }, { "disease_id": "DOID:0050866", "recommended_name": { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells." }, "synonyms": [ { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050866", "name": "mouth squamous cell carcinoma", "description": "" } ], "evidence": [ { "id": "0050866", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ] }, { "disease_id": "DOID:0060108", "recommended_name": { "id": "DOID:0060108", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060108", "name": "brain glioma", "description": "A brain cancer that has_material_basis_in glial cells." }, "synonyms": [ { "id": "DOID:0060108", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060108", "name": "lower grade glioma", "description": "" } ], "evidence": [ { "id": "0060108", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060108" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "evidence": [ { "id": "10652", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:1826", "recommended_name": { "id": "DOID:1826", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions." }, "synonyms": [ { "id": "DOID:1826", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1826", "name": "epilepsy syndrome", "description": "" }, { "id": "DOID:1826", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1826", "name": "epileptic syndrome", "description": "" } ], "evidence": [ { "id": "1826", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ] }, { "disease_id": "DOID:3319", "recommended_name": { "id": "DOID:3319", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3319", "name": "lymphangioleiomyomatosis", "description": "A lung disease that is characterized by progressive cystic destruction of the lung and lymphatic abnormalities, frequently associated with renal angiomyolipomas." }, "synonyms": [ { "id": "DOID:3319", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3319", "name": "lung lymphangioleiomyomatosis", "description": "" }, { "id": "DOID:3319", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3319", "name": "lymphangiomyomatosis", "description": "" }, { "id": "DOID:3319", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3319", "name": "pulmonary lymphangioleiomyomatosis", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "lymphangioleiomyomatosis", "description": "A multifocal neoplasm with perivascular epithelioid cell differentiation affecting almost exclusively females of child-bearing age. It is characterized by the presence of smooth muscle and epithelioid cells and by the proliferation of lymphatic vessels. Sites of involvement include the lungs, mediastinum, and the retroperitoneum. It usually presents with chylous pleural effusion or ascites." }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "lymphangioleiomyomatosis", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "lymphangioleiomyomatosis, somatic", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "lymphangiomyomatosis", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "lung lymphangioleiomyomatosis", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "pulmonary lymphangioleiomyomatosis", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "LAM", "description": "" }, { "id": "MONDO:0011705", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011705", "name": "lymphangio-myomatosis", "description": "" }, { "id": "MIM:606690", "resource": "MIM", "url": "https://www.omim.org/entry/606690", "name": "Lymphangioleiomyomatosis", "description": "Lymphangioleiomyomatosis" } ], "evidence": [ { "id": "3319", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:3319" } ] }, { "disease_id": "DOID:3525", "recommended_name": { "id": "DOID:3525", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:3525", "name": "middle cerebral artery infarction", "description": "" }, "synonyms": [], "evidence": [ { "id": "3525", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ] }, { "disease_id": "DOID:8947", "recommended_name": { "id": "DOID:8947", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8947", "name": "diabetic retinopathy", "description": "" }, "synonyms": [ { "id": "DOID:8947", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:8947", "name": "Retinal abnormality - diabetes-related", "description": "" } ], "evidence": [ { "id": "8947", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, mild, early-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": 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{ "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "3708786", "url": "http://www.informatics.jax.org/marker/MGI:3708786", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "YVQITTI", "url": "https://omabrowser.org/oma/group/YVQITTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10836", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10836", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10836:SF111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10836:SF111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00044", "url": "http://pfam.xfam.org/family/PF00044", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF02800", "url": "http://pfam.xfam.org/family/PF02800", "database": "Pfam", "categories": [ 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Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus OX=10090 GN=Gm10358 PE=1 SV=1 CANONICAL=A0A1D5RLD8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5RLD8-1", "url": "", "sequence": { "sequence": "MVKVGVNGFGRIGRLVTRAATCSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSIVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE", "length": 333, "header": "tr|A0A1D5RLD8-1|A0A1D5RLD8_MOUSE Isoform 1 of Glyceraldehyde-3-phosphate dehydrogenase OS=Mus musculus OX=10090 GN=Gm10358 PE=1 SV=1 CANONICAL=A0A1D5RLD8-1" }, "locus": { "chromosome": "8", "start_pos": 76133147, "end_pos": 76132149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000212864.2", "url": "https://www.ensembl.org/id/ENSMUST00000212864.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000148326.2", "url": "https://www.ensembl.org/id/ENSMUSP00000148326.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" }, { "name": "glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "id": "GO:0004365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004365", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" }, { "name": "peptidyl-cysteine S-nitrosylase activity", "id": "GO:0035605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035605", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" }, { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5RLD8", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10300", "name": "", "equation": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04797-1", "F1LUV3-1", "Q9ESV6-1", "A0A0G2K7M1-1", "E9PTV9-1", "E9PTN6-1", "M0R660-1", "O14556-1", "P04406-1", "P16858-1", "Q64467-1", "A0A1D5RLD8-1", "S4R1W1-1", "P00358-1", "P00359-1", "P00360-1", "Q94469-1", "P07486-1", "P07487-1", "Q7JY07-1" ], "evidence": [ { "id": "10300", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10300" } ] }, { "id": "66684", "name": "", "equation": "L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[GAPDH] = L-cysteinyl-[GAPDH] + S-nitroso-L-cysteinyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A0G2K7M1-1", "E9PTV9-1", "F1LUV3-1", "E9PTN6-1", "M0R660-1", "Q9ESV6-1", "P04797-1", "P04406-1", "P16858-1", "A0A1D5RLD8-1", "S4R1W1-1", "Q64467-1" ], "evidence": [ { "id": "66684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0G2K7M1", "gene_name": "AABR07030729.1", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "A0A0G2K7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K7M1" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "A0A0G2K7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K7M1" } ] } ] }, { "uniprot_ac": "A0A1D5RLD8", "gene_name": "Gm10358", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "A0A1D5RLD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "A0A1D5RLD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5RLD8" } ] } ] }, { "uniprot_ac": "E9PTN6", "gene_name": "LOC108352348", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "E9PTN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTN6" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "E9PTN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTN6" } ] } ] }, { "uniprot_ac": "E9PTV9", "gene_name": "AABR07032392.1", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "E9PTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTV9" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "E9PTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PTV9" } ] } ] }, { "uniprot_ac": "F1LUV3", "gene_name": "ENSRNOG00000066746", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "F1LUV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUV3" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "F1LUV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LUV3" } ] } ] }, { "uniprot_ac": "M0R660", "gene_name": "AABR07070043.1", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "M0R660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R660" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "M0R660", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0R660" } ] } ] }, { "uniprot_ac": "O14556", "gene_name": "GAPDHS", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "O14556", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14556" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "O14556", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14556" } ] } ] }, { "uniprot_ac": "P00358", "gene_name": "TDH2", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P00358", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00358" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P00358", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00358" } ] } ] }, { "uniprot_ac": "P00359", "gene_name": "TDH3", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P00359", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00359" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P00359", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00359" } ] } ] }, { "uniprot_ac": "P00360", "gene_name": "TDH1", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P00360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00360" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P00360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P00360" } ] } ] }, { "uniprot_ac": "P04406", "gene_name": "GAPDH", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P04406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04406" } ] }, { "ec_number": "2.6.99.-", "activity": "", "evidence": [ { "id": "P04406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04406" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P04406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04406" } ] } ] }, { "uniprot_ac": "P04797", "gene_name": "Gapdh", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P04797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04797" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P04797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04797" } ] }, { "ec_number": "2.6.99.-", "activity": "", "evidence": [ { "id": "P04797", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04797" } ] } ] }, { "uniprot_ac": "P07486", "gene_name": "Gapdh1", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P07486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07486" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P07486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07486" } ] } ] }, { "uniprot_ac": "P07487", "gene_name": "Gapdh2", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P07487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07487" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P07487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P07487" } ] } ] }, { "uniprot_ac": "P16858", "gene_name": "Gapdh", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "P16858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16858" } ] }, { "ec_number": "2.6.99.-", "activity": "", "evidence": [ { "id": "P16858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16858" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "P16858", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P16858" } ] } ] }, { "uniprot_ac": "Q64467", "gene_name": "Gapdhs", "activity": [ { "ec_number": "1.2.1.12", "activity": "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH.", "evidence": [ { "id": "Q64467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64467" } ] }, { "ec_number": "1.2.1.12", "activity": "", "evidence": [ { "id": "Q64467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64467" } ] } ] }, { "uniprot_ac": 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